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Vortioxetine (Lu AA 21004) is an antagonist of 5-HT 3A and 5-HT 7 receptors ( K i : 3.7 nM, 19 nM) and an inhibitor of serotonin transporter ( SERT ) ( K i : 1.6 nM), as well as a 5-HT 1A agonist and a partial agonist of 5-HT 1B ( K i : 15 nM, 33 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lu AA 21004. CAS No. 508233-74-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15414.
Vortioxetine-[d8]
One of the isotopic labelled form of Vortioxetine,which is a 5-HT receptor inhibitor as well as a serotonin transporter, and has been found to be an atypical antidepressant. Synonyms: 1-[2-[(2,4-Dimethylphenyl)thio]phenyl]piperazine-d8; 1-[2-(2,4-Dimethylphenylsulfanyl)phenyl]piperazine-d8. Grade: ≥90%. CAS No. 2140316-62-5. Molecular formula: C18H14D8N2S. Mole weight: 306.50.
Vortioxetine-[d8] HCl
An isotope labelled derivative of Vortioxetine. Vortioxetine is an antidepressant medication that is prescribed to treat depression. Synonyms: 1-[2-[[2,4-Di(methyl)phenyl]thio]phenyl]piperazine-2,2,3,3,5,5,6,6-d8. Grade: 95% by HPLC; 98% atom D. Molecular formula: C18H15D8ClN2S. Mole weight: 342.91.
Vortioxetine Glucose Adduct
Vortioxetine Glucose Adduct. Uses: For analytical and research use. Group: Impurity standards. Pack Sizes: 10MG. Catalog: APS013742. Format: Neat. Shipping: Room Temperature.
Vortioxetine hydrobromide
Vortioxetine (Lu AA 21004) hydrobromide is an antagonist of 5-HT 3A and 5-HT 7 receptors (K i : 3.7 nM, 19 nM) and an inhibitor of 5-hydroxytryptamine transporter (SERT) (K i : 1.6 nM), as well as a 5-HT 1A agonist and a partial 5-HT 1B agonist (K i : 15 nM, 33 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lu AA21004 hydrobromide. CAS No. 960203-27-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15414A.
Vortioxetine Impurity 14
Vortioxetine Impurity 14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1240670-85-2. Molecular formula: C28H34N4S. Mole weight: 458.67. Catalog: APB1240670852.
Vortioxetine Impurity 16
Vortioxetine Impurity 16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 16704-47-5. Molecular formula: C14H14S. Mole weight: 214.33. Catalog: APB16704475.
Vortioxetine Impurity 29
Vortioxetine Impurity 29. Uses: For analytical and research use. Group: Impurity standards. CAS No. 10468-16-3. Molecular formula: C6H6ClNO. Mole weight: 143.57. Catalog: APB10468163.
Vortioxetine Impurity 33
Vortioxetine Impurity 33. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1019453-85-0. Molecular formula: C14H15NS. Mole weight: 229.34. Catalog: APB1019453850.
Vortioxetine Impurity 59
Vortioxetine Impurity 59. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1025895-66-2. Molecular formula: C17H19NS. Mole weight: 269.41. Catalog: APB1025895662.
Vortioxetine Impurity 61
Vortioxetine Impurity 61. Uses: For analytical and research use. Group: Impurity standards. CAS No. 107832-66-6. Molecular formula: C10H14S. Mole weight: 166.28. Catalog: APB107832666.
Vortioxetine Lactose Adduct
Vortioxetine Lactose Adduct. Uses: For analytical and research use. Group: Impurity standards. Catalog: APS003497. Format: Neat.
3-Bromo-vortioxetine Hydrobromide
3-Bromo-vortioxetine Hydrobromide is an impurity of the drug Vortioxetine (V766000), which is a multimodal serotonergic agent. It inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptors and SERT. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C18H21BrN2S; HBr, Molecular Weight: 377.348091. US Biological Life Sciences.
Worldwide
3-Bromo Vortioxetine Hydrobromide
An impurity of Vortioxetine. Vortioxetine is a novel antidepressant medication used primarily to treat major depressive disorder (MDD) in adults. It works by modulating serotonin (5-HT) levels and activity in the brain through multiple mechanisms, including inhibition of serotonin reuptake, antagonism of 5-HT3, 5-HT7, and 5-HT1D receptors, partial agonism of 5-HT1B receptors, and agonism of 5-HT1A receptors. Synonyms: Vortioxetine Bromo Impurity HBr; 3-Bromo-vortioxetine Hydrobromide; Piperazine, 1-[2-[(3-bromo-2,4-dimethylphenyl)thio]phenyl]-, hydrobromide (1:1); 1-(2-((3-Bromo-2,4-dimethylphenyl)thio)phenyl)piperazine hydrobromide. Grade: ≥95%. CAS No. 2725536-51-4. Molecular formula: C18H21BrN2S.HBr. Mole weight: 458.25.
3-Chloro-Vortioxetine Hydrobromide
3-Chloro-Vortioxetine Hydrobromide. Uses: For analytical and research use. Group: Impurity standards. Pack Sizes: 5MG. Catalog: APS004543. Format: Neat. Shipping: Room Temperature.
5-Chloro-Vortioxetine Hydrobromide
5-Chloro-Vortioxetine Hydrobromide. Uses: For analytical and research use. Group: Impurity standards. Catalog: APS00536. Format: Neat.
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well as a Serotonin transporter, has been found to be an atypical antidepressant. Synonyms: Piperazine, 1-[2-[(2,4-dimethylphenyl)sulfonyl]phenyl]-; Vortioxetine Sulfone; Vonoprazan Impurity 10. CAS No. 1639263-80-1. Molecular formula: C18H22N2O2S. Mole weight: 330.44.
1-(2-((2,5-Dimethylphenyl)thio)phenyl)piperazine
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well as a Serotonin transporter, has been found to be an atypical antidepressant. Synonyms: Piperazine, 1-[2-[(2,5-dimethylphenyl)thio]phenyl]-; Vortioxetine Impurity 04. CAS No. 508233-77-0. Molecular formula: C18H22N2S. Mole weight: 298.45.
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well as a Serotonin transporter, has been found to be an atypical antidepressant. Synonyms: 4-Desmethyl 6-Methyl Vortioxetine. CAS No. 508233-76-9. Molecular formula: C18H22N2S. Mole weight: 298.45.
One of the impurities of Vortioxetine, which is a 5-HT receptor inhibitor as well as a serotonin transporter. Vortioxetine has been found to be an atypical antidepressant. Synonyms: Vortioxetine Impurity 1 HBr salt; Piperazine, 1-[2-[(2-methylphenyl)thio]phenyl]-, hydrobromide (1:1). Grade: 95%. CAS No. 1293343-91-5. Molecular formula: C17H21BrN2S. Mole weight: 365.33.
One of the impurities of Vortioxetine, which is a 5-HT receptor inhibitor as well as an Serotonin transporter, and has been found to be an atypical antidepressant. Synonyms: Piperazine, 1-[2-[(3-chloro-2,4-dimethylphenyl)thio]phenyl]-. Grade: 95%. CAS No. 2425618-51-3. Molecular formula: C18H21ClN2S. Mole weight: 332.89.
One of the impurities of Vortioxetine, which is a 5-HT receptor inhibitor as well as an Serotonin transporter, and has been found to be an atypical antidepressant. Synonyms: Piperazine, 1-[2-[(3-methylphenyl)thio]phenyl]-, hydrochloride. Grade: 95%. CAS No. 1293342-89-8. Molecular formula: C17H20N2S.HCl. Mole weight: 320.88.
1-[2-[ (4-Chloro-2, 5-dimethylphenyl) thio]phenyl]-piperazine is an intermediate in the synthesis of 3-Chloro-Vortioxetine which is an impurity of Vortioxetine (V766000), a multimodal serotonergic agent. Vortioxetine inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C18H21ClN2S. US Biological Life Sciences.
One of the impurities of Vortioxetine, which is a 5-HT receptor inhibitor as well as an Serotonin transporter, and has been found to be an atypical antidepressant. Grade: 95%. CAS No. 1240670-87-4. Molecular formula: C18H21ClN2S. Mole weight: 332.89.
1-(2-(o-tolylthio)phenyl)piperazine hydrochloride
One of the impurities of Vortioxetine, which is a 5-HT receptor inhibitor as well as a serotonin transporter. Vortioxetine has been found to be an atypical antidepressant. Synonyms: Vortioxetine Impurity 1 HCl salt; 1-[2-(2-Methylphenylsulfanyl)phenyl]piperazine hydrochloride; Piperazine, 1-[2-[(2-methylphenyl)thio]phenyl]-, hydrochloride (1:1). Grade: 95%. CAS No. 1293342-91-2. Molecular formula: C17H21ClN2S. Mole weight: 320.88.
1-(3-((2,4-dimethylphenyl)thio)phenyl)piperazine
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well as a Serotonin transporter, has been found to be an atypical antidepressant. Synonyms: Piperazine, 1-[3-[(2,4-dimethylphenyl)thio]phenyl]-; Vortioxetine Impurity J; Vortioxetine Impurity 07. CAS No. 2137588-68-0. Molecular formula: C18H22N2S. Mole weight: 298.45.
1-[4-[2-[ (2, 4-Dimethylphenyl) thio]phenyl]-1-piperazinyl]ethanone is a useful chemical reagent. It is an impurity of Vortioxetine which is a multimodal serotonergic agent that inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT (1,2,3). Group: Biochemicals. Grades: Highly Purified. CAS No. 1801352-86-2. Pack Sizes: 10mg, 50mg. Molecular Formula: C20H24N2OS, Molecular Weight: 340.48. US Biological Life Sciences.
Worldwide
1-(4-((2,4-dimethylphenyl)thio)phenyl)piperazine
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well as a Serotonin transporter, has been found to be an atypical antidepressant. Synonyms: Vortioxetine impurity S; Piperazine, 1-[4-[(2,4-dimethylphenyl)thio]phenyl]-; Vonoprazan Impurity 08. CAS No. 1815608-51-5. Molecular formula: C18H22N2S. Mole weight: 298.45.
One of the impurities of Vortioxetine which is a 5-HT receptor inhibitor as well as a Serotonin transporter, has been found to be an atypical antidepressant. Synonyms: Piperazine, 1,4-bis[2-[(2,4-dimethylphenyl)thio]phenyl]-; Vortioxetine Impurity 02. CAS No. 2243045-82-9. Molecular formula: C32H34N2S2. Mole weight: 510.76.
1-O-(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)- β-D-glucopyranuronic Acid 2,3,4-Triacetate Methyl Ester is an intermediate in synthesizing N-Hydroxy Vortioxetine O- β-D-Glucuronide Sodium Salt (H996005), which is a metabolite of Vortioxetine (V766000, HBr); a multimodal serotonergic agent which inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT. Group: Biochemicals. Grades: Highly Purified. CAS No. 319926-19-7. Pack Sizes: 1g, 2.5g. Molecular Formula: C21H21NO12. US Biological Life Sciences.
1-O-(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)-β-D-glucopyranuronic Acid 2,3,4-Triacetate Methyl Ester is an intermediate in synthesizing N-Hydroxy Vortioxetine O-β-D-Glucuronide Sodium Salt, which is a metabolite of Vortioxetine; a multimodal serotonergic agent which inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT. Synonyms: (2S,3R,4S,5S,6S)-2-((1,3-Dioxoisoindolin-2-yl)oxy)-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl Triacetate; β-D-Glucopyranuronic acid, 1-O-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-, methyl ester, 2,3,4-triacetate. CAS No. 319926-19-7. Molecular formula: C21H21NO12. Mole weight: 479.39.
1-O-Acetamido- β-D-glucopyranuronic Acid 3,4-Diacetate Methyl Ester is an intermediate in synthesizing N-Hydroxy Vortioxetine O- β-D-Glucuronide Sodium Salt (H996005), which is a metabolite of Vortioxetine (V766000, HBr); a multimodal serotonergic agent which inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C13H19NO10. US Biological Life Sciences.
1-O-Acetamido-β-D-glucopyranuronic Acid 3,4-Diacetate Methyl Ester is an intermediate in synthesizing N-Hydroxy Vortioxetine O-β-D-Glucuronide Sodium Salt, which is a metabolite of Vortioxetine, a multimodal serotonergic agent which inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT. Synonyms: (2S,3S,4R,5R,6S)-6-(Acetamidooxy)-5-hydroxy-2-(methoxycarbonyl)tetrahydro-2H-pyran-3,4-diyl Diacetate. Molecular formula: C13H19NO10. Mole weight: 349.29.
1-O-Amino- β-D-glucopyranuronic Acid 2,3,4-Triacetate Methyl Ester is an intermediate in synthesizing N-Hydroxy Vortioxetine O- β-D-Glucuronide Sodium Salt (H996005), which is a metabolite of Vortioxetine (V766000, HBr); a multimodal serotonergic agent which inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT. Group: Biochemicals. Grades: Highly Purified. CAS No. 319926-20-0. Pack Sizes: 500mg, 1g. Molecular Formula: C13H19NO10. US Biological Life Sciences.
1-O-Amino-β-D-glucopyranuronic Acid 2,3,4-Triacetate Methyl Ester is an intermediate in synthesizing N-Hydroxy Vortioxetine O-β-D-Glucuronide Sodium Salt, which is a metabolite of Vortioxetine, a multimodal serotonergic agent which inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT. Synonyms: (2S,3R,4S,5S,6S)-2-(Aminooxy)-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl Triacetate; β-D-Glucopyranuronic acid, 1-O-amino-, methyl ester, 2,3,4-triacetate. CAS No. 319926-20-0. Molecular formula: C13H19NO10. Mole weight: 349.29.
2, 2'-[[2-[ (2, 4-Dimethylphenyl) thio]phenyl]imino]bis-ethanol is an intermediate in synthesizing N-Hydroxy Vortioxetine O- β-D-Glucuronide Sodium Salt (H996005), which is a metabolite of Vortioxetine (V766000, HBr); a multimodal serotonergic agent which inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT. Group: Biochemicals. Grades: Highly Purified. CAS No. 1818381-14-4. Pack Sizes: 25mg, 50mg. Molecular Formula: C18H23NO2S. US Biological Life Sciences.
Worldwide
2-[ (2, 4-Dimethylphenyl) sulfanyl]aniline
2-[ (2, 4-Dimethylphenyl) sulfanyl]aniline is used in the study of N-O-glucuronide metabolites of Lu AA21004 (Vortioxetine [V766000]), an antidepressant. Group: Biochemicals. Grades: Highly Purified. CAS No. 1019453-85-0. Pack Sizes: 50mg, 250mg. Molecular Formula: C14H15NS. US Biological Life Sciences.
(2S,3R,4S,5S,6S)-2-(((2-((2-((2,4-Dimethylphenyl)thio)phenyl)(2-hydroxyethyl)amino)ethyl)amino)oxy)-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl Triacetate is an intermediate in synthesizing N-Hydroxy Vortioxetine O-β-D-Glucuronide Sodium Salt, which is a metabolite of Vortioxetine; a multimodal serotonergic agent which inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT. Molecular formula: C31H40N2O11S. Mole weight: 648.72.
(2S,3R,4S,5S,6S)-2-(((2-((2-Bromoethyl)(2-((2,4-dimethylphenyl)thio)phenyl)amino)ethyl)amino)oxy)-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl Triacetate is an intermediate in synthesizing N-Hydroxy Vortioxetine O-β-D-Glucuronide Sodium Salt, which is a metabolite of Vortioxetine; a multimodal serotonergic agent which inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT. Molecular formula: C31H39BrN2O10S. Mole weight: 711.62.
(2S,3S,4R,5R,6S)-6-(((2-((2-((2,4-Dimethylphenyl)thio)phenyl)(2-hydroxyethyl)amino)ethyl)amino)oxy)-5-hydroxy-2-(methoxycarbonyl)tetrahydro-2H-pyran-3,4-diyl Diacetate is an intermediate in the synthesis of N-Hydroxy Vortioxetine O-β-D-Glucuronide Sodium Salt, which is a metabolite of Vortioxetine; a multimodal serotonergic agent which inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT. Molecular formula: C29H38N2O10S. Mole weight: 606.68.
3-Chloro-2,4-dimethyl-benzenesulfonyl Chloride
3-Chloro-2,4-dimethyl-benzenesulfonyl Chloride is an intermediate in the synthesis of 3-Chloro-Vortioxetine (C424140) which is an impurity of Vortioxetine (V766000), a multimodal serotonergic agent. Vortioxetine inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT. Group: Biochemicals. Grades: Highly Purified. CAS No. 1783755-80-5. Pack Sizes: 2.5g, 5g. Molecular Formula: C8H8Cl2O2S. US Biological Life Sciences.
4-[2-[(2,4-Dimethylphenyl)thio]phenyl]-morpholinyl-2-N-1-O-amino-β-D-glucopyranuronic Acid 2,3,4-Triacetate Methyl Ester is an intermediate in synthesizing N-Hydroxy Vortioxetine O-β-D-Glucuronide Sodium Salt, which is a metabolite of Vortioxetine; a multimodal serotonergic agent which inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT. Synonyms: (2S,3R,4S,5S,6S)-2-(((4-(2-((2,4-Dimethylphenyl)thio)phenyl)morpholin-2-yl)amino)oxy)-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl Triacetate. Molecular formula: C31H38N2O11S. Mole weight: 646.71.
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