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Amlodipine Impurity 22 (Z-Isomer) is an impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain. Synonyms: (Z)-2-[(2-Chlorophenyl)methylene]-4-[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]-3-oxobutanoic Acid Ethyl Ester. Molecular formula: C23H20ClNO6. Mole weight: 441.86.
(E)-4-Hydroxy Toremifene-d6 (~10% Z-isomer)
Labeled (E)-4-Hydroxytoremifene. (E)-4-Hydroxytoremifene is the inactive (E)-isomer of 4-Hydroxy Toremifene. Group: Biochemicals. Alternative Names: (E) -4-[4-Chloro-1-[4-[2-[ (dimethyl-d6) amino]ethoxy]phenyl]-2-phenyl-1-butenyl]phenol; (E)-4-Hydroxytoremifene-d6. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Triprolidine hydrochloride Z-Isomer
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
1-Z-4-Hydroxy methyl piperidine. Group: Biochemicals. Alternative Names: Benzyl 4- (hydroxymethyl) tetrahydro-1 (2H) pyridinecarboxylate; 4-Hydroxymethyl-piperidine-1-carboxylic acid benzyl ester; Z-isonipecotinol. Grades: Highly Purified. CAS No. 122860-33-7. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences.
Worldwide
Cefprozil Monohydrate EP Impurity D
An impurity of Cefprozil, which is a cephalosporin antibiotic used to treat a variety of bacterial infections. Synonyms: Cefprozil USP Related Compound D; 7-Amino-3-propenylcephalosporanic acid (Z-isomer). Grade: 90%. CAS No. 106447-44-3. Molecular formula: C10H12N2O3S. Mole weight: 240.28.
Cefprozil Monohydrate EP Impurity H
Cefprozil EP impurity H is an impurity of Cefprozil, which is a semisynthetic, broad-spectrum, second-generation cephalosporin with antibacterial activity. Synonyms: Cefprozil related compound H (Z)-isomer; N-Acyl cefprozil (Z-isomer); (Z)-N-((2R)-2-amino-2-(4-hydroxyphenyl)acetyl) cefprozil; (6R,7R)-7-{(R)-2-[(R)-2-Amino-2-(4-hydroxyphenyl)acetamido]-2-(4-hydroxyphenyl)acetamido}-8-oxo-3-[(Z)-prop-1-enyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. Grade: ≥95%. Molecular formula: C26H26N4O7S. Mole weight: 538.57.
Cinnarizine Impurity B
(Z)-Cinnarizine is the Z-isomer of Cinnarizine. Synonyms: (Z)-Cinnarizine; 1-(Diphenylmethyl)-4-[(2Z)-3-phenyl-2-propen-1-yl]piperazine; (Z)-1-(Diphenylmethyl)- 4-(3-phenyl-2-propenyl)piperazine; cis-Cinnarizine. Grade: > 95%. CAS No. 750512-44-8. Molecular formula: C26H28N2. Mole weight: 368.51.
cis-Lacidipine
Z-Isomer of Lacidipine; a dihydropyridine calcium channel blocker. Antihypertensive. Synonyms: (Z)-4-[2-[3-(1,1-Dimethylethoxy)-3-oxo-1-propenyl]phenyl]-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic Acid Diethyl Ester. Grade: > 95%. CAS No. 103890-79-5. Molecular formula: C26H33NO6. Mole weight: 455.55.
Damascenone
Damascenone ((E/Z)-Damascenone) is an active compound of Epipremnum pinnatum with anti-inflammatory activity [1]. Damascenone is a mixture complex of E-isomer-Damascenone and Z-isomer Damascenone. Uses: Scientific research. Group: Natural products. Alternative Names: (E/Z)-Damascenone. CAS No. 23696-85-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N2543.
Endoxifen E-isomer hydrochloride
Endoxifen E-isomer hydrochloride (E-Endoxifen hydrochloride), an E-isomer of Endoxifen, is an impurity in Endoxifen Z-isomer agent substance. Endoxifen E-isomer hydrochloride exhibits antiestrogenic effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E-Endoxifen hydrochloride. CAS No. 1197194-61-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-18719C.
(Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile
An impurity of Rilpivirine. Rilpivirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV-1 infections by binding to and inhibiting the activity of the viral reverse transcriptase, thereby preventing the transcription of viral RNA into DNA. Synonyms: Rilpivirine Z-Nitrile Impurity; (2Z)-3-(4-Amino-3,5-dimethylphenyl)-2-propenenitrile; 2-Propenenitrile, 3-(4-amino-3,5-dimethylphenyl)-, (2Z)-; Rilpivirine Nitrile Z-isomer. Grade: ≥95%. CAS No. 661489-22-1. Molecular formula: C11H12N2. Mole weight: 172.23.
An impurity of Azelastine. Azelastine is a selective histamine H1 receptor antagonist used primarily for the treatment of allergic rhinitis and perennial rhinitis, including the relief of nasal congestion, runny nose, sneezing and itchy nose. Synonyms: Azelastine EP Impurity E (Z-Isomer); (3Z)-3-[(4-Chlorophenyl)methylene]-1(3H)-isobenzofuranone; (Z)-3-[(4-Chlorophenyl)methylene]-1(3H)-isobenzofuranone; (Z)-Azelastine hydrochloride impurity E; (Z)-3-(4-Chlorobenzal)phthalide; Azelastine Hydrochloride Imp. E (EP) Z-Isomer; Azelastine Imp. E (EP) Z-Isomer; Azelastine Impurity E (Z-Isomer). Grade: ≥95%. CAS No. 105279-16-1. Molecular formula: C15H9ClO2. Mole weight: 256.68.
(Z)-4EGI-1
(Z)-4EGI-1, the Z-isomer of 4EGI-1, is an inhibitor of eIF4E/eIF4G interaction and translation initiation and has anticancer activity. It effectively binds to eIF4E with an IC50 of 43.5 μM and a Kd of 8.74 μM. Synonyms: (2Z)-2-{[4-(3,4-Dichlorophenyl)-1,3-thiazol-2-yl]hydrazono}-3-(2-nitrophenyl)propanoic acid; Benzenepropanoic acid, α-[2-[4-(3,4-dichlorophenyl)-2-thiazolyl]hydrazinylidene]-2-nitro-, (αZ)-. Grade: ≥98%. CAS No. 901787-88-0. Molecular formula: C18H12Cl2N4O4S. Mole weight: 451.28.
(Z)-Cinnarizine-d8
(Z)-Cinnarizine-d8 is the labelled Z-isomer of Cinnarizine. Cinnarizine is an anti-histamine agent used to treat balance disorders. Synonyms: 1-(Diphenylmethyl)-4-[(2Z)-3-phenyl-2-propen-1-yl]piperazine-d8; (Z)-1-(Diphenylmethyl)-4-(3-phenyl-2-propenyl)piperazine-d8; cis-Cinnarizine-d8. Grade: > 95%. Molecular formula: C26H20D8N2. Mole weight: 376.56.
(Z)?-Desethyl methyl tamoxifen
An impurity of Tamoxifen. Tamoxifen is a selective estrogen receptor modulator (SERM) widely used in breast cancer treatment and prevention, particularly for estrogen receptor-positive (ER+) tumors. It works by competitively blocking estrogen receptors in breast tissue, inhibiting cancer cell growth. Synonyms: (Z)-2-(4-(1,2-Diphenylprop-1-en-1-yl)phenoxy)-N,N-dimethylethan-1-amine; (Z)?-2-[4-(1,?2-Diphenyl-1-propenyl)?phenoxy]?-N,?N-dimethylethanamine; (Z)-2-[p-(1,2-Diphenylpropenyl)phenoxy]-N,N-dimethylethylamine; Tamoxifen Citrate EP Impurity D (Z-Isomer); Tamoxifen EP Impurity D (Z-Isomer); Tamoxifen Impurity D (Z-Isomer). Grade: ≥95%. CAS No. 15917-50-7. Molecular formula: C25H27NO. Mole weight: 357.49.
(Z)-Eltanexor
(Z)-Eltanexor is the less active isomer of KPT-8602, which is an orally bioavailable XPO1 (also known as CRM1) inhibitor. Synonyms: KPT-8602 (Z-isomer); Eltanexor Z-isomer; (2Z)-3-(3-(3,5-Bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-2-(pyrimidin-5-yl)prop-2-enamide; (Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-2-(pyrimidin-5-yl)acrylamide; 5-Pyrimidineacetamide, α-[[3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]methylene]-, (αZ)-. Grade: ≥95%. CAS No. 1642300-78-4. Molecular formula: C17H10F6N6O. Mole weight: 428.29.
ζ-carotene isomerase
The enzyme catalyses the cis-trans isomerization of the 15-15' carbon-carbon double bond in 9,15,9'-tricis-ζ-carotene, which is required for biosynthesis of all plant carotenoids. Requires heme b. Group: Enzymes. Synonyms: Z-ISO; 15-cis-ζ-carotene isomerase. Enzyme Commission Number: EC 5.2.1.12. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5443; ζ-carotene isomerase; EC 5.2.1.12; Z-ISO; 15-cis-ζ-carotene isomerase. Cat No: EXWM-5443.
An impurity of Loratadine, which is a histamine H1 receptor antagonist used to treat allergies. Synonyms: 1(2H)-Pyridinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-3,4-dihydro-, ethyl ester, (4Z)-; Dehydro Loratadine Isomer A (Z-isomer); Ethyl (4Z)-4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-3,4-dihydro-1(2H)-pyridinecarboxylate; Ethyl (Z)-4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-3,4-dihydropyridine-1(2H)-carboxylate. Grade: >95%. CAS No. 2482644-44-8. Molecular formula: C22H21ClN2O2. Mole weight: 380.87.
(Z)-JIB-04
(Z)-JIB-04 is a Z-isomer of JIB-04, which is a small-molecule histone demethylase inhibitor with antitumor activity. JIB-04 selectively inhibits tumor growth via targeting various tumorigenic signaling pathways. Synonyms: 5-Chloro-2-(2-(phenyl(pyridin-2-yl)methylene)hydrazinyl)pyridine; JIB-04 Z-isomer. CAS No. 199596-24-2. Molecular formula: C17H13ClN4. Mole weight: 308.769.
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