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Zileuton. Group: Biochemicals. Grades: Highly Purified. CAS No. 111406-87-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Zileuton
Zileuton is a potent and selective inhibitor of 5-lipoxygenase with antiasthmatic properties. Group: Inhibitors. Alternative Names: (±)-N-hydroxy-N-(1-benzo[b]thien-2-ylethyl)urea. CAS No. 111406-87-2. Molecular formula: C11H12N2O2S. Mole weight: 236.29. Appearance: A Crystalline Solid. Purity: 0.99. Catalog: ACM111406872.
Zileuton
Zileuton is a potent and selective inhibitor of 5-lipoxygenase with antiasthmatic properties. Uses: Scientific research. Group: Signaling pathways. Alternative Names: A 64077; Abbott 64077. CAS No. 111406-87-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14164.
Zileuton β-D-Glucuronide
A metabolite of Zileuton. Group: Biochemicals. Alternative Names: 1-O-[(Aminocarbonyl)(1-benzo[b]thien-2-ylethyl)amino]- β-D-glucopyranuronic Acid. Grades: Highly Purified. CAS No. 141056-63-5. Pack Sizes: 2.5mg. US Biological Life Sciences.
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Zileuton-d4
Zileuton-d4 is the deuterium labeled Zileuton. Zileuton (A 64077) is a potent and selective inhibitor of 5-lipoxygenase with antiasthmatic properties. Group: Inhibitors. Alternative Names: N-(1-Benzo[b]thien-2-yl-ethyl)-N-hydroxyurea-d4; A-64077-d4; Abbott 64077-d4; Leutrol-d4; Zyflo-d4. CAS No. 1189878-76-9. Molecular formula: C11H8D4N2O2S. Mole weight: 240.31. Appearance: White Solid. Purity: 0.96. IUPACName: 1-[1-(1-benzothiophen-2-yl)-1,2,2,2-tetradeuterioethyl]-1-hydroxyurea. Canonical SMILES: CC(C1=CC2=CC=CC=C2S1)N(C(=O)N)O. Catalog: ACM1189878769.
Zileuton-d4 (major)
An inhibitor of 5-lipoxygenase, the initial enzyme in the biosynthesis of leukotrienes from Arachidonic Acid. Used as an antiasthmatic. Group: Biochemicals. Alternative Names: N-(1-Benzo[b]thien-2-yl-ethyl)-N-hydroxyurea-d4;A-64077-d4; Abbott 64077-d4; Leutrol-d4; Zyflo-d4. Grades: Highly Purified. CAS No. 1189878-76-9. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Zileuton Glucuronide
One of the impurities of Zileuton, which is a 5-lipoxygenase inhibitor and could be used as an antiasthmatic agent. Molecular formula: C17H20N2O8S. Mole weight: 412.42.
Zileuton Impurity 1
One of the impurities of Zileuton, which is a 5-lipoxygenase inhibitor and could be used as an antiasthmatic agent. Synonyms: 1-(Benzo[b]thien-2-yl)ethanol; 2-(1-Hydroxyethyl)benzothiophene; 2-(1-Hydroxyethyl)thianaphthene; α-Methyl-2-benzo[b]thiophenemethanol; α-Methylbenzo[b]thiophene-2-methanol. CAS No. 51868-95-2. Molecular formula: C10H10OS. Mole weight: 178.25.
Zileuton Impurity 2
One of the impurities of Zileuton, which is a 5-lipoxygenase inhibitor and could be used as an antiasthmatic agent. Synonyms: N-(1-Benzo[b]thien-2-yl-ethyl)-N-hydroxy O-phenyl Carbamate; Phenyl (1-(Benzo[b]thiophen-2-yl)ethyl)(hydroxy)carbamate. CAS No. 1026256-93-8. Molecular formula: C17H15NO3S. Mole weight: 313.38.
An inhibitor of 5-lipoxygenase, the initial enzyme in the biosynthesis of leukotrienes from Arachidonic Acid. Used as an antiasthmatic. Group: Biochemicals. Alternative Names: N-(1-Benzo[b]thien-2-yl-ethyl)-N-hydroxyurea;A-64077; Abbott 64077; Leutrol; Zyflo. Grades: Highly Purified. CAS No. 111406-87-2. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Zileuton Related Compound A
One of the impurities of Zileuton, which is a 5-lipoxygenase inhibitor and could be used as an antiasthmatic agent. Synonyms: N-Dehydroxyzileuton; N-(1-Benzo[b]thien-2-ylethyl)urea; (1-Benzo[b]thien-2-ylethyl)urea; A 66193; Abbott 66193. CAS No. 171370-49-3. Molecular formula: C11H12N2OS. Mole weight: 220.29.
Zileuton sodium
Zileuton sodium (A 64077 sodium) is a potent and selective inhibitor of 5-lipoxygenase , exhibiting inflammatory activities. Uses: Scientific research. Group: Signaling pathways. Alternative Names: A 64077 sodium; Abbott 64077 sodium. CAS No. 118569-21-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14164A.
Zileuton sodium
Zileuton sodium is an inhibitor of 5-lipoxygenase, and thus inhibits leukotrienes(LTB4, LTC4, LTD4 and LTE4) formation with an IC50 value of 0.5μM. Zileuton sodium has been reported to concentration-dependently inhibit the 5-lipoxygenase activity with an IC50 value of 0.5μM in RBL-1cell lysate. In addition, Zileuton sodium has been found to be a potent inhibitor of LTB formation with an IC50 value of 0.6μM. Furthermore, stimulated with A23187, Zileuton sodium has shown a dose-dependent reduction in LTB4 and 5-HETE generation in rat leukocyte with IC50 values of 0.38μM and 0.31μM, respectively. About 40-fold higher concentrations of Zileuton sodium also reduced the production of PGE2 with a IC50 of 16μM. Synonyms: Zyflo sodium. Grades: >98%. CAS No. 118569-21-4. Molecular formula: C11H11N2NaO2S. Mole weight: 258.27.
A metabolite of Zileuton. Group: Biochemicals. Alternative Names: N-Hydroxy-N-[1-(1-oxidobenzo[b]thien-2-yl)ethyl]urea. Grades: Highly Purified. CAS No. 1147524-83-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Zileuton Sulfoxide
One of the impurities of Zileuton, which is a 5-lipoxygenase inhibitor and could be used as an antiasthmatic agent. Synonyms: N-Hydroxy-N-[1-(1-oxidobenzo[b]thien-2-yl)ethyl]urea. CAS No. 1147524-83-1. Molecular formula: C11H12N2O3S. Mole weight: 252.29.
1-(Benzo[b]thien-2-yl)ethanol
1-(Benzo[b]thien-2-yl)ethanol is an intermediate used to prepare amino sugar and related sugar derivatives of indolopyrrolocarbazole s as antitumors. It is also an impurity of Zileuton (Z420000), an inhibitor of 5-lipoxygenase, the initial enzyme in the biosynthesis of leukotrienes from Arachidonic Acid. Zileuton is used as an antiasthmatic. Group: Biochemicals. Grades: Highly Purified. CAS No. 51868-95-2. Pack Sizes: 5mg, 25mg. Molecular Formula: C10H10OS, Molecular Weight: 178.25. US Biological Life Sciences.
Worldwide
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