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Z-Gly-Pro-AMC is a fluorogenic substrate. Z-Gly-Pro-AMC is hydrolyzed by prolyl endopeptidase to generate highly fluorescent 7-amido-4-methylcoumarin (HY-D0027). (?ex=380 nm, ?em=465 nm)[1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 68542-93-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-D1670.
Z-GLY-PRO-AMC
It is a fluorogenic substrate used for post-proline cleaving enzyme prolyl endopeptidase. Synonyms: N-Carbobenzoxyglycyl-prolyl-4-methylcoumarinyl amide; Z-Gly-pro-NH-Mec; 7-(N-Benzyloxycarbonyl-glycyl-prolyl-amido)-4-methylcoumarin; (S)-benzyl 2-(2-(4-methyl-2-oxo-2H-chromen-7-ylcarbamoyl)pyrrolidin-1-yl)-2-oxoethylcarbamate. CAS No. 68542-93-8. Molecular formula: C25H25N3O6. Mole weight: 463.48.
Z-GLY-PRO-ARG-4MBNA COH
Z-GLY-PRO-ARG-4MBNA COH is a thrombin substrate which has been modeled after a thrombin cleavage site in human fibrinogen. It can be used for a sensitive assay of antithrombin III activity. Synonyms: Z-Gly-Pro-Arg-MNA; Z-Gly-Pro-Arg-4-methoxy-2-naphthylamide; Z-Gly-Pro-Arg-4MβNA. CAS No. 66647-41-4. Molecular formula: C32H39N7O6. Mole weight: 617.71.
Z-Gly-Pro-Arg 4-methoxy-2-naphthylamide trifluoroacetate salt
Z-Gly-Pro-Arg-AMC hydrochloride a fluorescent trypsin and cathepsin K substrate. Z-Gly-Pro-Arg-AMC hydrochloride can be used to determine trypsin and cathepsin K activity [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 201928-42-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4217.
Z-Gly-Pro-Arg-Mca Hydrochloride
Z-GPR-AMC is a fluorogenic substrate for cathepsin K, granzyme A, and thrombin. Synonyms: Z-Gly-Pro-Arg-AMC HCl; L-Argininamide, N-[(phenylmethoxy)carbonyl]glycyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-,monohydrochloride(9ci). CAS No. 201928-42-9. Molecular formula: C31H38ClN7O7. Mole weight: 656.13.
Z-Gly-Pro-OH. Synonyms: Z-L-glycyl-L-proline; N-Cbz-glycyl-L-proline; (2S)-1-(2-{[(benzyloxy)carbonyl]amino}acetyl)pyrrolidine-2-carboxylic acid; Z Gly Pro OH. Grade: 99%. CAS No. 1160-54-9. Molecular formula: C15H18N2O5. Mole weight: 306.32.
Z-Gly-Pro-OH 99+%
Z-Gly-Pro-OH 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g. US Biological Life Sciences.
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z-Gly-pro-osu
z-Gly-pro-osu. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Z-GLY-PRO-OSU;Z-GLYCYL-L-PROLINE HYDROXYSUCCINIMIDE ESTER;Z-GLYCYL-L-PROLINE HYDROXYSUCCINIMIDESTER. Product Category: Heterocyclic Organic Compound. CAS No. 38417-02-6. Molecular formula: C19H21N3O7. Mole weight: 403.39. Purity: 0.96. IUPACName: (2,5-dioxopyrrolidin-1-yl)(2S)-1-[2-(phenylmethoxycarbonylamino)acetyl]pyrrolidine-2-carboxylate. Canonical SMILES: C1CC(N(C1)C(=O)CNC(=O)OCC2=CC=CC=C2)C(=O)ON3C(=O)CCC3=O. Product ID: ACM38417026. Alfa Chemistry ISO 9001:2015 Certified.
Z-Gly-Pro-pNA
Z-Gly-Pro-pNA is a substrate for measuring prolyl endopeptidase (PEP) inhibitory activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 65022-15-3. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-137220.
Z-Gly-Pro-pNA
Substrate for the post proline cleaving enzyme. Synonyms: N-CBZ-Glycyl-L-proline 4-nitroanilide; (S)-benzyl 2-(2-(4-nitrophenylcarbamoyl)pyrrolidin-1-yl)-2-oxoethylcarbamate; Z Gly Pro pNA. Grade: ≥ 99.0% (HPLC). CAS No. 65022-15-3. Molecular formula: C21H22N4O6. Mole weight: 426.43.
Z-Gly-Sar-OH
Z-Gly-Sar-OH. Synonyms: N-(((benzyloxy)carbonyl)glycyl)-N-methylglycine; 2-(2-(benzyloxycarbonylamino)-N-methylacetamido)acetic acid; 2-[methyl-(2-phenylmethoxycarbonylaminoacetyl)amino]acetic acid; Z Gly Sar OH. Grade: ≥ 99% (HPLC). CAS No. 7801-91-4. Molecular formula: C13H16N2O5. Mole weight: 280.28.
Z-Gly-Sar-OH
Z-Gly-Sar-OH. Group: Biochemicals. Grades: Highly Purified. CAS No. 7801-91-4. Pack Sizes: 250mg, 500mg, 1g. US Biological Life Sciences.
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Z-Gly-Sar-OH 99+%
Z-Gly-Sar-OH 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g. US Biological Life Sciences.
Worldwide
Z-Gly-Tyr-NH2
Z-Gly-Tyr-NH2. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 2.5g. US Biological Life Sciences.
Z-Guggulsterone. Group: Biochemicals. Alternative Names: (17Z)-Pregna-4,17(20)-diene-3,16-dione; (17Z)-Guggulsterone; 4,17(20)-cis-Pregnadiene-3,6-dione; cis-Guggulsterone. Grades: Highly Purified. CAS No. 39025-23-5. Pack Sizes: 5mg. Molecular Formula: C21H28O2, Molecular Weight: 312.45. US Biological Life Sciences.
Worldwide
Z-Guggulsterone
Z-Guggulsterone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Guggulsterone. Appearance: Off-White to Light Yellow powder. CAS No. 39025-23-5. Molecular formula: C21H28O2. Mole weight: 312.45. Purity: 0.95. Product ID: ACM39025235. Alfa Chemistry ISO 9001:2015 Certified.
z-His-4-nitro-phe-phe-ome
z-His-4-nitro-phe-phe-ome. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Z-HIS-P-NITRO-PHE-PHE-OME;Z-HIS-4-NITRO-PHE-PHE-OME. Product Category: Heterocyclic Organic Compound. CAS No. 15574-28-4. Molecular formula: C33H34N6O8. Mole weight: 642.66. Product ID: ACM15574284. Alfa Chemistry ISO 9001:2015 Certified.
z-His-ala-oh
z-His-ala-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Z-L-HISTIDYL-L-ALANINE;Z-HIS-ALA-OH. Product Category: Heterocyclic Organic Compound. CAS No. 13056-38-7. Molecular formula: C17H20N4O5. Mole weight: 360.36. Product ID: ACM13056387. Alfa Chemistry ISO 9001:2015 Certified.
Z-His-Glu-Lys-MCA is a peptide substrate for Lys-Gingipain (Kgp) that can be used in the assays of the Kgp activity. Synonyms: Z-His-Glu-Lys-AMC; Cbz-His-Glu-Lys-MCA; Cbz-His-Glu-Lys-AMC; Z-HEK-AMC; Benzyloxycarbonyl-L-histidyl-L-glutamyl-L-lysine 4-methylcoumaryl-7-amide. CAS No. 327182-05-8. Molecular formula: C35H41N7O9. Mole weight: 703.74.
Z-His-NH·NH2. Group: Biochemicals. Alternative Names: Z-L-histidine hydrazide. Grades: Highly Purified. CAS No. 49706-31-2. Pack Sizes: 10g. US Biological Life Sciences.
Worldwide
z-His-tyr-tyr-oet
z-His-tyr-tyr-oet. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-ALPHA-CARBOBENZOXY-L-HISTIDYL-L-TYROSYL-L-TYROSINE ETHYL ESTER;Z-HIS-TYR-TYR-OET;CBZ-HIS-TYR-TYR-ETHYL ESTER. Product Category: Heterocyclic Organic Compound. CAS No. 13053-63-9. Molecular formula: C34H37N5O8. Mole weight: 643.69. Product ID: ACM13053639. Alfa Chemistry ISO 9001:2015 Certified.
Z-Hyp(tBu)-OMe. CAS No. 146951-99-7. Molecular formula: C18H25O5N1. Mole weight: 335.4.
Zibotentan
Zibotentan (ZD4054) is a potent, selective and orally active endothelin A (ET A ) receptor antagonist with a K i of 13 nM. Zibotentan has no inhibitory effect on ETB. Zibotentan has anticancer effects and can be used for castration-resistant prostate cancer (CRPC) research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZD4054. CAS No. 186497-07-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10088.
Ziconotide acetate. Group: Biochemicals. Alternative Names: ω-Conotoxin M VIIA acetate; ω-Conopeptide MVIIA acetate; Prialt acetate. Grades: Highly Purified. CAS No. 914454-03-8. Pack Sizes: 1mg, 2mg. Molecular Formula: C104H176N36O34S7. US Biological Life Sciences.
Worldwide
Ziconotide acetate
Ziconotide acetate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ω-Conotoxin M VIIA Acetate; ω-Conopeptide MVIIA Acetate; Prialt Acetate; SNX 111. Product Category: Heterocyclic Organic Compound. CAS No. 914454-03-8. Molecular formula: C104H176N36O34S7. Mole weight: 2699.19. Purity: 0.96. Product ID: ACM914454038. Alfa Chemistry ISO 9001:2015 Certified.
Ziconotide acetate
Ziconotide acetate (SNX-111 acetate), a peptide, is a potent and selective block of N-type calcium channels antagonist. Ziconotide acetate reduces synaptic transmission, and can be used for chronic pain research [1]. Uses: Scientific research. Group: Peptides. Alternative Names: SNX-111 acetate. CAS No. 914454-03-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0062B.
Ziconotide Polyacetate
Α selective antagonist of N-type voltage sensitive calcium channels (VSCC). Blocks neurotransmitter release by preventing depolarization-induced calcium influx. Used as a ligand for binding studies of voltage sensitive calcium channels. Analgesic; neuroprotective. Group: Biochemicals. Alternative Names: ω-Conotoxin M VIIA Acetate; ω-Conopeptide MVIIA Acetate; Prialt Acetate; SNX 111. Grades: Highly Purified. Pack Sizes: 250ug. US Biological Life Sciences.
Worldwide
Zidapamide
Zidapamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ZIDAPUMIDE;Zidapamide;4-Chloro-N-(1-methyl-1,3-dihydroisoindol-2-yl)-3-sulfamoylbenzamide;3-(Aminosulfonyl)-4-chloro-N-(1,3-dihydro-1-methyl-2H-isoindol-2-yl)benzamide;4-Chloro-N-(1,3-dihydro-1-methyl-2H-isoindol-2-yl)-3-sulfamoylbenzamide;Isodapamide. Product Category: Heterocyclic Organic Compound. CAS No. 75820-08-5. Molecular formula: C16H16ClN3O3S. Mole weight: 365.83. Product ID: ACM75820085. Alfa Chemistry ISO 9001:2015 Certified.
Zidebactam
Zidebactam (WCK-5107) is a potent β-lactamase inhibitor [1]. Zidebactam also is a penicillin-binding protein2 (PBP2) inhibitor with an IC 50 of 0.26 μg/mL [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WCK-5107. CAS No. 1436861-97-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120859.
Zidesamtinib
Zidesamtinib (NVL-520) is a potent, selective, orally active and brain-penetrant inhibitor of diverse ROS1 fusions and resistance mutations, with IC50s of 0.7 and 7.9 nM for wild-type ROS1 and ROS1 G2032R, respectively, and spares TRK inhibition. Zidesamtinib can be used for the research of cancer[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NVL-520; NUV-520. CAS No. 2739829-00-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-152292.
Zidovudine
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardsbritish pharmacopoeiaeuropean pharmacopoeia (ph. eur.)pharmacopoeial standards. Alternative Names: Zidovudine, BP Zidovudine and Lamivudine Impurity Standard, 1-(3-Azido-2,3-dideoxy-?-d-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione, Zidovudine (GR 63367X).
Zidovudine
Zidovudine is a nucleoside reverse transcriptase inhibitor ( NRTI ), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Azidothymidine; AZT; ZDV. CAS No. 30516-87-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-17413.
Zidovudine
Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-AZIDO-3-DEOXYTHYMIDINE;1-(4-azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1h-pyrimidine-2,4-dione;1-((2R,4S,5S)-4-AZIDO-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-2-YL)-5-METHYL-1H-PYRIMIDINE-2,4-DIONE;AZT;AZIDOTHYMIDINE;ZIDOVUDINE;3'-azido-3'-deoxy-thymidin;bwa509u. Product Category: Inhibitors. CAS No. 30516-87-1. Molecular formula: C10H13N5O5. Mole weight: 283.24. Purity: 0.9993. Product ID: ACM30516871. Alfa Chemistry ISO 9001:2015 Certified.
Zidovudine
Zidovudine is a nucleoside reverse transcriptase inhibitor that, following triphosphorylation by thymidine kinase, potently blocks replication of HIV (EC50 = 3 nM) with low cytotoxicity (CC50 > 5 μM). It is commonly used in combination therapy to slow the replication of HIV in vivo. Uses: Anti-hiv agents; antimetabolites; antimetabolites, antineoplastic; reverse transcriptase inhibitors. Synonyms: 3'-Azido-3-deoxythymidine; AZT; BWA509U; BWA 509U; BWA-509U; ZDV; Azidothymidine; Retrovir; Timazid; NSC 602670; 3'-Azido-2',3'-dideoxythymidine; 1-(3-Azido-2,3-dideoxy-β-D-glycero-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione; 1-[(2R,4S,5S)-4-Azido-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methylpyrimidin-2,4(1H,3H)-dione; 1-(3-Azido-2,3-dideoxy-β-D-ribofuranosyl)thymine. Grade: ≥95%. CAS No. 30516-87-1. Molecular formula: C10H13N5O4. Mole weight: 267.24.
Zidovudine Glucuronide-[13C6]
One of the isotopic labelled impurities of Zidovudine, which is a reverse transcriptase inhibitor and could restrain the HIV-1 replication. Synonyms: (2S,3S,4S,5R)-6-[[(2S)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid-13C6. Molecular formula: C10[13C]6H21N5O10. Mole weight: 449.30.
Zidovudine Related Compound B
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Zidovudine Related Compound C
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Zidovudine Related Compound D
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Z-IETD-FMK
Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a selective and cell permeable caspase-8 inhibitor[1]. Z-IETD-FMK is also a granzyme B inhibitor[5]. Uses: Scientific research. Group: Peptides. Alternative Names: Z-IE(OMe)TD(OMe)-FMK. CAS No. 210344-98-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101297.
Z-IETD-FMK
Z-IETD-FMK is a selective and cell permeable caspase 8 inhibitor. Z-IETD-FMK inhibits T cell proliferation induced by PHA or anti-CD3 plus anti-CD28 without toxicity of resting T cells. Synonyms: caspase-8 inhibitor; Z-IE(OMe)TD(OMe)-FMK; Z-Ile-Glu(OMe)-Thr-Asp(OMe)-CH2F; Z-Ile-Glu(OMe)-Thr-Asp(OMe) fluoromethylketone; N-benzyloxycarbonyl-Ile-Glu(OMe)-Thr-Asp(OMe)-fluoromethylketone; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone. Grade: ≥95%. CAS No. 210344-98-2. Molecular formula: C30H43FN4O11. Mole weight: 654.69.
Z-Ile-Glu(OMe)-Thr-DL-Asp(OMe)-fluoromethylketone is a cell permeable inhibitor of caspase-8 and granzyme B. The bis-methyl ester of Z-Ile-Glu(OMe)-Thr-DL-Asp(OMe)-fluoromethylketone blocks CD95-induced apoptosis. Synonyms: Z-IETD-FMK; Z-IE(OMe)TD(OMe)-FMK; Methyl (5S,8S,11S)-5-[(2S)-2-butanyl]-14-(fluoroacetyl)-11-[(1R)-1-hydroxyethyl]-8-(3-methoxy-3-oxopropyl)-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oate. Grade: ≥95%. CAS No. 1926163-59-8. Molecular formula: C30H43FN4O11. Mole weight: 654.69.
PSI is a drug that blocks the action of proteasomes, protein complexes that degrade unneeded and damaged proteins. It causes dopaminergic cell death in vitro and prevents activation of NF-κB in response to TNF-α and okadaic acid by inhibiting IκB-α degradation. Uses: Cysteine proteinase inhibitors. Synonyms: Proteasome Inhibitor I; PSI peptide; L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-isoleucyl-L-alpha-glutamyl-N-[(1S)-1-formyl-3-methylbutyl]-, 1,1-dimethylethyl ester. Grade: ≥ 90 % by HPLC. CAS No. 158442-41-2. Molecular formula: C32H50N4O8. Mole weight: 618.76.
Z-Ile-Leu-aldehyde ia a cell-permeable and reversible inhibitor that inhibits γ-secretase and Notch signaling. It induces apoptosis of murine MOPC315.BM myeloma cells with high Notch activity in vitro. It has potent anti-MM activity and reduces osteolytic lesions in vivo. Uses: Gamma secretase inhibitors and modulators. Synonyms: Z-IL-CHO; GSI-XII; Z-Ile-Leu-al; Z Ile Leu al; Z IL CHO; Gamma-secretase inhibitor XII; [(1S,2S)-1-((S)-1-Formyl-3-methyl-butylcarbamoyl)-2-methyl-butyl]-carbamic acid benzyl ester; Benzyl ((2S,3S)-3-methyl-1-(((S)-4-methyl-1-oxopentan-2-yl)amino)-1-oxopentan-2-yl)carbamate; N-benzyloxycarbonyl-L-isoleucyl-L-leucinal. Grade: ≥95%. CAS No. 161710-10-7. Molecular formula: C20H30N2O4. Mole weight: 362.46.
Zileuton is a potent and selective inhibitor of 5-lipoxygenase with antiasthmatic properties. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (±)-N-hydroxy-N-(1-benzo[b]thien-2-ylethyl)urea. Product Category: Inhibitors. Appearance: A Crystalline Solid. CAS No. 111406-87-2. Molecular formula: C11H12N2O2S. Mole weight: 236.29. Purity: 0.99. Product ID: ACM111406872. Alfa Chemistry ISO 9001:2015 Certified.
Zileuton
Zileuton is a potent and selective inhibitor of 5-lipoxygenase with antiasthmatic properties. Uses: Scientific research. Group: Signaling pathways. Alternative Names: A 64077; Abbott 64077. CAS No. 111406-87-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14164.
Zileuton
Zileuton is an orally active inhibitor of 5-lipoxygenase, and thus inhibits leukotrienes (LTB4, LTC4, LTD4, and LTE4) formation, used to decrease the symptoms of asthma. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: A-64077; A64077; A 64077; Zileuton; trade name ZYFLO; ZYFLO CR. Grade: >98%. CAS No. 111406-87-2. Molecular formula: C11H12N2O2S. Mole weight: 236.29.
Zileuton
Zileuton. Group: Biochemicals. Grades: Highly Purified. CAS No. 111406-87-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Zileuton β-D-Glucuronide
A metabolite of Zileuton. Group: Biochemicals. Alternative Names: 1-O-[(Aminocarbonyl)(1-benzo[b]thien-2-ylethyl)amino]- β-D-glucopyranuronic Acid. Grades: Highly Purified. CAS No. 141056-63-5. Pack Sizes: 2.5mg. US Biological Life Sciences.