A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Aggregation-induced emission luminogens (AIEgen) were tailored to detect biological thiols. Maleimide is attached to the TPE core, giving TPE-Thiol.16. The reaction is inspired by the fast and efficient thiolene click reaction between maleimide and thiols, TPE-Thiol is not emissive in both solution and aggregated states, due to the photo-induced electron transfer from TPE to maleimide. However, reaction with thiol groups can interrupt the electron transfer process and turn-on the emission of TPE. TPE-Thiol can be used for labelling of protein carrying cysteine residues in the physiological media and poly(acrylamide) gel electrophoresis assays. Uses: Tpe-thiol is an aggregation-induced emission (aie) material for the "click" chemistry, with alkene and thio group detection. Group: Bioelectronic materials organic light-emitting diode (oled) materials other materials. Alternative Names: TPE-Thiol. CAS No. 1245606-71-6. Pack Sizes: 25 mg in glass insert. Molecular formula: 441.52. CC (C=C1)=CC=C1/C (C2=CC=CC=C2)=C (C3=CC=CC=C3)/C4=CC=C (N5C (C=CC5=O)=O)C=C4. 1S/C31H23NO2/c1-22-12-14-25 (15-13-22)30 (23-8-4-2-5-9-23)31 (24-10-6-3-7-11-24)26-16-18-27 (19-17-26)32-28 (33)20-21-29 (32)34/h2-21H, 1H3/b31-30+, CIMVFJJQFXGASK-NVQSTNCTSA-N. CIMVFJJQFXGASK-NVQSTNCTSA-N.
Aggregation-induced emission luminogens (AIEgen) were tailored to detect biological thiols. Maleimide is attached to the TPE core, giving TPE-Thiol.16. The reaction is inspired by the fast and efficient thiolene click reaction between maleimide and thiols, TPE-Thiol is not emissive in both solution and aggregated states, due to the photo-induced electron transfer from TPE to maleimide. However, reaction with thiol groups can interrupt the electron transfer process and turn-on the emission of TPE. TPE-Thiol can be used for labelling of protein carrying cysteine residues in the physiological media and poly(acrylamide) gel electrophoresis assays. Uses: Tpe-thiol is an aggregation-induced emission (aie) material for the "click" chemistry, with alkene and thio group detection. Group: Bioelectronic materialsorganic light-emitting diode (oled) materialsother materials. Alternative Names: TPE-Thiol. CAS No. 1245606-71-6. Mole weight: 441.52. Canonical SMILES: CC (C=C1)=CC=C1/C (C2=CC=CC=C2)=C (C3=CC=CC=C3)/C4=CC=C (N5C (C=CC5=O)=O)C=C4. Catalog: ACM1245606716.
1- (4- (1, 3, 4-Oxadiazol-2-yl) phenyl) -3- ( (5- (2, 2, 2-trifluoroacetyl) thiophene-2-carbonyl) oxy) guanidine is an intermediate in the synthesis of potential class II human histone deacetylase inhibitors. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 10mg. Molecular Formula: C16H10F3N5O4S. US Biological Life Sciences.
14,15 β-dihydroxyklaineanone. Group: Biochemicals. Grades: Plant Grade. CAS No. 137359-82-1. Pack Sizes: 5mg. Molecular Formula: C20H28O8, Molecular Weight: 396.17. US Biological Life Sciences.
Worldwide
14,15-Dehydro-21-acetyl Fluocinolone Acetonide
14,15-Dehydro-21-acetyl Fluocinolone Acetonide is an intermediate in the synthesis of 14,15-Dehydro Fluocinolone Acetonide (D230135); an impurity of Fluocinolone Acetonide (F455800) which is a glucocorticoid and anti-inflammatory agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C26H30F2O7, Molecular Weight: 492.51. US Biological Life Sciences.
A derivative of Triamcinolone acetonide. A corticosteroid. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
14,15-Dehydro budesonide
14,15-Dehydro budesonide. Group: Biochemicals. Alternative Names: (11b,16a)-16,17-[Butylidenebis(oxy)]-11,21-dihydroxypregna-1,4,14-triene-3,20-dione. Grades: Highly Purified. CAS No. 131918-64-4. Pack Sizes: 10mg, 20mg, 50mg, 100mg, 250mg. Molecular Formula: C25H32O6. US Biological Life Sciences.
Worldwide
14,15-Dehydro Fluocinolone Acetonide
14,15-Dehydro Fluocinolone Acetonide. Uses: For analytical and research use. Group: Impurity standards. Catalog: APS00222. Format: Neat.
14,15-Dehydro Fluocinolone Acetonide
14,15-Dehydro Fluocinolone Acetonide is an impurity of Fluocinolone Acetonide (F455800); a glucocorticoid and anti-inflammatory agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2mg. Molecular Formula: C24H28F2O6, Molecular Weight: 450.47. US Biological Life Sciences.
Worldwide
14,15-Dehydro Flurandrenolide
14,15-Dehydro Flurandrenolide is an impurity of Flurandrenolide (F598650), a glucocorticoid; antipsoriatic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C24H31FO6, Molecular Weight: 434.5. US Biological Life Sciences.
Worldwide
14,15-dehydro Leukotriene B4
14,15-dehydro Leukotriene B4 is an LTB4 receptor antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 114616-11-4. Pack Sizes: 25ug, 50ug. Molecular Formula: C20H32O4, Molecular Weight: 336.47. US Biological Life Sciences.
Worldwide
14,15-Dehydro leukotriene b4
Heterocyclic Organic Compound. Alternative Names: 14,15-DEHYDRO LEUKOTRIENE B4;5S,12R-DIHYDROXY-6Z,8E,10E-EICOSATRIEN-14-YNOIC ACID. CAS No. 114616-11-4. Molecular formula: C20H30O4. Mole weight: 336.47. Catalog: ACM114616114.
14,15-Dehydro leukotriene B4
14,15-Dehydro leukotriene B4 is a dihydroxy fatty acid derived from arachidonic acid through the 5-lipoxygenase pathway. Synonyms: 14,15-dehydro LTB4; 5S,12R-dihydroxy-6Z,8E,10E-eicosatrien-14-ynoic acid. Grades: ≥97%. CAS No. 114616-11-4. Molecular formula: C20H30O4. Mole weight: 334.5.
14,15-Dehydro Triamcinolone Acetonide
Cas No. 1260149-96-9.
14,15-Dehydro Triamcinolone Acetonide
14,15-Dehydro Triamcinolone Acetonide is a derivative of Triamcinolone acetonide. A corticosteroid. Group: Biochemicals. Grades: Highly Purified. CAS No. 1260149-96-9. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
14,15-Epoxyeicosatrienoic Acid (±14,15-EET)
Epoxyeicosatrienoic Acid (EET) has antihypertensive and anti-inflammatory properties and play a role in the maintenance of renal vascular function. N,?N'-?dicyclohexylurea (DCU) increased release of 14,15-EET when the cells were stimulated with a calcium ionophore. Also, it is derived from Arachidonic Acid, which is an essential fatty acid and a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. Arachidonic Acid occurs in liver, brain, glandular organs, and depot fats of animals, in small amounts in human depot fats, and Arachidonic Acid is also a constituent of animal phosphatides. Group: Biochemicals. Alternative Names: (5Z,8Z,11Z)-13-(3-Pentyl-2-oxiranyl)-5,8,11-tridecatrienoic Acid; 14(15)-EET; 14(15)-Epoxy-5Z,8Z,11Z-eicosatrienoic Acid; (±)14,15-EET; (±)14,15-EpETrE; (all-Z)-13-(3-Pentyloxiranyl)-5,8,11-tridecatrienoic Acid. Grades: Highly Purified. CAS No. 197508-62-6. Pack Sizes: 50ug, 100ug, 500ug. Molecular Formula: C??H??O?, Molecular Weight: 320.47. US Biological Life Sciences.
Worldwide
14,15-Leukotriene C4
14,15-Leukotriene C4 is an acute inflammatory mediator. Group: Biochemicals. Grades: Highly Purified. CAS No. 75290-60-7. Pack Sizes: 25ug, 50ug. Molecular Formula: C30H47N3O9S, Molecular Weight: 625.77. US Biological Life Sciences.
Worldwide
14,15-Leukotriene e4
Heterocyclic Organic Compound. Alternative Names: 14,15-Leukotriene E4, CTK8E7650, 1000852-57-2. CAS No. 1000852-57-2. Molecular formula: C23H37NO5S. Mole weight: 439.6. Appearance: A solution in methanol. Purity: 0.96. IUPACName: (15S)-14-(2-amino-2-carboxyethyl)sulfanyl-15-hydroxyicosa-5,8,10,12-tetraenoic acid. Canonical SMILES: CCCCCC (C (C=CC=CC=CCC=CCCCC (=O)O)SCC (C (=O)O)N)O. Catalog: ACM1000852572.
14,15-Leukotriene E4
14,15-Leukotriene E4 is a Leukotriene that increases vascular permeability of human endothelial cell monolayers. Group: Biochemicals. Grades: Highly Purified. CAS No. 1000852-57-2. Pack Sizes: 25ug, 50ug. Molecular Formula: C23H37NO5S, Molecular Weight: 439.61. US Biological Life Sciences.
1-[4-[2-[ (2, 4-Dimethylphenyl) thio]phenyl]-1-piperazinyl]ethanone is a useful chemical reagent. It is an impurity of Vortioxetine which is a multimodal serotonergic agent that inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT (1,2,3). Group: Biochemicals. Grades: Highly Purified. CAS No. 1801352-86-2. Pack Sizes: 10mg, 50mg. Molecular Formula: C20H24N2OS, Molecular Weight: 340.48. US Biological Life Sciences.
1-[4- (2, 4-Difluorobenzoyl) piperidin-1-yl]ethanone is a chemical reagent used in the synthesis of antiproliferative agents as well as for piperidines displaying 5-HT2 antagonist activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 84162-82-3. Pack Sizes: 250mg, 1g. Molecular Formula: C14H15F2NO2, Molecular Weight: 267.27. US Biological Life Sciences.
1-[4-(2-(Azepan-1-yl)ethoxy)benzyl]-5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indole-d4 is an intermediate in the synthesis of Bazedoxifene-d4 (B129247). Bazedoxifene-d4 is a labeled nonsteroidal selective estrogen receptor modulator (SERM). Bazedoxifene is used as an antiosteoporotic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C44H42D4N2O3. US Biological Life Sciences.
An intermediate in the syntheis of a metabolite of the anti-cancer drug Tamoxifen. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
1- (4- (2-Hydroxy-3- (isopropylamino) propoxy) phenyl) -2-methoxyethanone has been used as a reactant in the synthesis of metoprolol (M338790) metabolites. Group: Biochemicals. Grades: Highly Purified. CAS No. 73723-85-0. Pack Sizes: 10mg, 100mg. Molecular Formula: C15H23NO4. US Biological Life Sciences.
An impurity of Olmesartan, which is a specific angiotensin II type 1 (AT1) receptor antagonist with antihypertensive effect. Synonyms: 1-(4-(2-Hydroxypropan-2-yl)-2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazol-5-yl)ethanone; 1227626-50-7; 1-[5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(1-trityltetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]ethanone. CAS No. 1227626-50-7. Molecular formula: C44H42N6O2. Mole weight: 686.84.
An impurity of Metoprolol, a β1 selective aryloxypropanolamine andrenergic antagonist. It is used in the treatment of a variety of cardiovascular disorder. Synonyms: Metoprolol Impurity 16. Grades: ≥95%. CAS No. 1416440-64-6. Molecular formula: C15H22O5. Mole weight: 282.33.
1-(4-(2-Methoxyphenyl)thiazol-2-yl)guanidine Hydrobromide is used in the preparation of antiulcer agents, specifically 4-Substituted 2-guanidinothiazoles, which are reversible, competitive, and selective inhibitors of gastric H+,K+-ATPase. It is also used in the preparation of guanidinothiazole derivatives as Maillard reaction inhibitors and antioxidants. Group: Biochemicals. Grades: Highly Purified. CAS No. 123310-81-6. Pack Sizes: 500mg, 1g. Molecular Formula: C11H12N4OS; HBr, Molecular Weight: 248.31. US Biological Life Sciences.
1-(4-(2-methyl-6-oxopiperidin-1-yl)phenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one is an impurity of Apixaban, a direct factor Xa inhibitor used as an anticoagulant for the prevention of venous thromboembolism and stroke in atrial fibrillation. Synonyms: 1-[4-(2-Methyl-6-oxo-1-piperidinyl)phenyl]-3-(4-morpholinyl)-5,6-dihydro-2(1H)-pyridinone; 2(1H)-Pyridinone, 5,6-dihydro-1-[4-(2-methyl-6-oxo-1-piperidinyl)phenyl]-3-(4-morpholinyl)-. CAS No. 2098457-93-1. Molecular formula: C21H27N3O3. Mole weight: 369.46.
1-(4-(((2R,4S)-2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-4-(4-(4H-1,2,4-triazol-4-yl)phenyl)piperazine is an intermediate in the synthesis of Deoxo Anhydro Itraconazole Bromide (D231675). Deoxo Anhydro Itraconazole Bromide is an impurity of Itraconazole (I937500), which is orally active antimycotic drug structurally related to Ketoconazole (K186000). Antifungal. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C31H30Cl2N8O3. US Biological Life Sciences.
1-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-(4-nitrophenyl)piperazine is an intermediate in the synthesis of derivatives of Itraconazole (I937500), an orally active antimycotic and antifungal compound. Group: Biochemicals. Grades: Highly Purified. CAS No. 1437468-92-2. Pack Sizes: 10mg, 100mg. Molecular Formula: C29H28Cl2N6O5. US Biological Life Sciences.
14-3-3 Antagonist I, 2-5 ( (S) -2- (2- (4-Azidobenzamido) acetamido) -3- ( (4-hydroxyphenethyl) amino) -3-oxopropyl-dihydrogen Phosphate)
A cell-permeable dipeptidyl-phosphoserine compound that effectively disrupts 14-3-3 interaction with its ligands (IC50=2.6uM against TMR-GG-RLSHpSSLPG binding to human 14-3-3 sigma), including Raf-1 and p53. Shown to induce caspase-3 activation and apoptotic cell death in human lung adenocarcinoma A549 cultures (100uM) in a time-dependent manner. Group: Biochemicals. Grades: Purified. Pack Sizes: 5mg. Molecular Formula: C??H??N?O?P, Molecular Weight: 506.4. US Biological Life Sciences.
Worldwide
14-3-3η Protein inhibitor 1
14-3-3η Protein inhibitor 1 (Compound C11) is a 14-3-3η protein inhibitor with a K D of 35 μM. 14-3-3η Protein inhibitor 1 shows inhibitory activities against several typical human liver cancer cell lines. 14-3-3η Protein inhibitor 1 induces cell apoptosis and G1-S cell cycle arrest with good metabolic stability [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2770842-10-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-146302.
1-[4-[3- (4-Acetyl-2-methoxyphenoxy) propoxy]-3-ethoxyphenyl]ethanone is an impurity of Iloperidone (I267200); an atypical antipsychotic drug used in the treatment of schizophrenia. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 250mg. Molecular Formula: C22H26O6, Molecular Weight: 386.44. US Biological Life Sciences.
1-[4-[3- (4-Acetyl-2-methoxyphenoxy) propoxy]-3-ethoxyphenyl]ethanone-d3 is the isotope labelled analog of 1-[4-[3- (4-Acetyl-2-methoxyphenoxy) propoxy]-3-ethoxyphenyl]ethanone (A186535); an impurity of Iloperidone (I267200) which is an atypical antipsychotic drug used in the treatment of schizophrenia. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C22H23D3O6, Molecular Weight: 389.46. US Biological Life Sciences.
Worldwide
1,4:3,6-Dianhydro-2,5-di-O-ethyl-D-glucitol
Cas No. 30915-81-2.
1,4:3,6-Dianhydro-2,5-di-O-methyl-D-glucitol
1,4:3,6-Dianhydro-2,5-di-O-methyl-D-glucitol is a man-made entity applied in the research of kidney dysfunctions, ocular ailments, and cerebral edema alike. Synonyms: 1,4:3,6-Dianhydrosorbitol 2,5-dimethyl ether; 2,5-Di-O-methyl-1,4:3,6-dianhydro-D-glucitol; Isosorbide dimethyl ether; Dimethyl isosorbide. CAS No. 5306-85-4. Molecular formula: C8H14O4. Mole weight: 174.19.
1,4:3,6-Dianhydro-2,5-di-O-methyl-D-Iditol
1,4:3,6-Dianhydro-2,5-di-O-methyl-D-Iditol, a widely utilized chemical compound in the synthesis of insulin and several other medicinal compounds, possesses anti-diabetic and anti-inflammatory properties. Scientific research has explored its potential in managing diabetes and associated pathologies. Molecular formula: C8H14O4. Mole weight: 174.19.