A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Norethindrone derivative. Might be a human carcinogen. Group: Biochemicals. Alternative Names: (17α)-17-[(Trimethylsilyl)oxy]-19-norpregn-4-en-20-yn-3-one; 17-(Trimethylsiloxy)-19-nor-17α-pregn-4-en-20-yn-3-one. Grades: Highly Purified. CAS No. 28426-43-9. Pack Sizes: 100mg. US Biological Life Sciences.
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17-O-Trimethylsilyl Norethindrone
17-O-Trimethylsilyl Norethindrone is a derivative of Norethindrone, which is an oral contraceptive involved in the inhibition of cytosolic sulfotransferases. Synonyms: (17α)-17-[(Trimethylsilyl)oxy]-19-norpregn-4-en-20-yn-3-one; 17-(Trimethylsiloxy)-19-nor-17α-pregn-4-en-20-yn-3-one. Grades: 98%. CAS No. 28426-43-9. Molecular formula: C23H34O2Si. Mole weight: 370.60.
17-O-Trimethylsilyl Prednisolone 22-O-Acetate
17-O-Trimethylsilyl Prednisolone 22-O-Acetate is an intermediate in synthesizing 17-Dehydroxy Prednisolone (D230025), used in the synthesis of a novel anti-inflammatory steroid acid ester. Also used in the synthesis of corticosteroids. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C26H38O6Si. US Biological Life Sciences.
Worldwide
17-O-Trimethylsilyl Prednisolone 22-O-Acetate
17-O-Trimethylsilyl Prednisolone 22-O-Acetate is an intermediate in the synthesis of Prednisolone, which is a glucocorticoid and an anti-inflammatory drug used to treat central nervous system disorders. Synonyms: [2-[(8S,9S,10R,11S,13S,14S,17R)-11-hydroxy-10,13-dimethyl-3-oxo-17-trimethylsilyloxy-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate. Molecular formula: C26H38O6Si. Mole weight: 474.66.
17-Oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-docosahexaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DHA that is produced endogenously by aspirin-enhanced COX-2 activity. Synonyms: EFOX; 17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-DHA; 17-oxo-DHA; (4Z,7Z,10Z,13Z,15E,19Z)-17-Oxodocosahexaenoic acid. Grades: ≥90%. CAS No. 1233715-28-0. Molecular formula: C22H30O3. Mole weight: 342.5.
Docosapentaenoic acid (DPA) is a ω-3 fatty acid found in fish oils. 17-Oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DPA that is produced endogenously by aspirin-enhanced COX-2 activity. Synonyms: EFOX; 17-oxo-DPA; 17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-DPA; 17-keto-(7Z,10Z,13Z,15E,19Z)-docosapentaenoic acid. Grades: ≥95%. CAS No. 1233715-33-7. Molecular formula: C22H32O3. Mole weight: 344.5.
17-Oxo Betamethasone
A metabolite of Betamethasone. Group: Biochemicals. Alternative Names: (11 β,16 β)- 9-Fluoro-11-hydroxy-16-methyl-androsta-1,4-diene-3,17-dione; 9α-Fluoro-11 β-hydroxy-16 β-methyl-1,4-androstadiene-3,17-dione; NSC 52437. Grades: Highly Purified. CAS No. 3109-1-1. Pack Sizes: 1mg. US Biological Life Sciences.
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17-Oxo dexamethasone
17-Oxo dexamethasone. Group: Biochemicals. Alternative Names: 9-Fluoro-11-hydroxy-16-methyl-(11b,16a ) androsta-1,4-diene-3,17-dione; 9-Fluoro-11b-hydroxy-16a-methyl androsta-1,4-diene-3,17-dione; NSC 50909. Grades: Highly Purified. CAS No. 1880-61-1. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C20H25FO3. US Biological Life Sciences.
Worldwide
17-Oxo Dexamethasone
. Uses: A metabolite of dexamethasone. Synonyms: 9-Fluoro-11-hydroxy-16-methyl-(11β,16α ) Androsta-1,4-diene-3,17-dione; 9-Fluoro-11β-hydroxy-16α-methyl Androsta-1,4-diene-3,17-dione; NSC 50909. CAS No. 1880-61-1. Molecular formula: C20H25FO3. Mole weight: 332.41.
17-Oxospartein
17-Oxospartein. Group: Biochemicals. Grades: Highly Purified. CAS No. 489-72-5. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C15H24N2O. US Biological Life Sciences.
Worldwide
17-PA
17-PA is an antagonist of neurosteroid GABA potentiation. It can selectively reduce the effects of 5α-reduced steroids compared to 5β-reduced steroids. Synonyms: 17-PA; 17 PA; 17PA; 17-Phenyl-(3α,5α)-androst-16-en-3-ol. Grades: ≥99% by HPLC. CAS No. 694438-95-4. Molecular formula: C25H34O. Mole weight: 350.54.
17-PA
Selective antagonist of neurosteroid potentiation and direct gating of GABAA receptors. Selectively reduces the effects of 5α-reduced steroids compared to 5 β-reduced steroids and displays no effect on potentiation evoked by barbiturates and benzodiazepines. Attenuates 3α,5α-THP-induced loss of righting reflex and total sleep time following i.c.v administration in rats. Group: Biochemicals. Grades: Highly Purified. CAS No. 694438-95-4. Pack Sizes: 10mg, 50mg. Molecular Formula: C25H34O. US Biological Life Sciences.
Worldwide
17-Phenoxy trinor prostaglandin F2α
17-Phenoxy trinor prostaglandin F2α (17-phenoxy trinor PGF2α) is a novel analog of PGF2&alpha. Synonyms: 17-phenoxy trinor PGF2&alpha. Grades: >98%. Molecular formula: C23H32O6. Mole weight: 404.5.
17-Phenyl-18,19,20-trinor-PGF2α 1,15-Lactone
17-Phenyl-18,19,20-trinor-PGF2α 1,15-Lactone is an impurity of Bimatoprost (B386800), which is an antiglaucoma agent. Bimatoprost is an synthetic prostamide; structurally related to prostaglandin F2α. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C23H30O4, Molecular Weight: 370.48. US Biological Life Sciences.
Worldwide
17-Phenyl-18,19,20-trinor-PGF2α 1,15-Lactone
17-Phenyl-18,19,20-trinor-PGF2α 1,15-Lactone is one of bimatoprost impurities. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Synonyms: Bimatoprost 1,15-Lactone; 17-Phenyl-18,19,20-trinor-prostaglandin F2-alpha 1,15-lactone; 5H-Cyclopent(e)oxacyclotridecin-5-one, 3,6,7,8,11,11a,12,13,14,14a-decahydro-12,14-dihydroxy-3-(2-phenylethyl)-, (3S-(1E,3R*,9Z,11aS*,12R*,14S*,14aS*))-; Bimatoprost Impurity 4. CAS No. 62411-15-8. Molecular formula: C23H30O4. Mole weight: 370.48.
17-Phenyl trinor PGF2α isopropyl ester
17-phenyl trinor PGF2α N-ethyl amide is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name Bimatoprost.1 The N-ethyl amide prostaglandin prodrugs are converted to the active free acid more slowly than the analogous prostaglandin ester prodrugs such as latanoprost.2 This product is the isopropyl ester of the free acid prostaglandin which corresponds to Bimatoprost. The free acid, 17-phenyl trinor PGF2α, is a potent FP receptor agonist.3 In human and animal models of glaucoma, FP receptor agonist activity corresponds very closely with intraocular hypotensive activity. The 17-phenyl trinor PGF2α isopropyl ester derivative is examined for IOP-lowering activity during the development of latanoprost.4 At the dose of 3 μg/eye in the monkey, 17-phenyl trinor PGF2α isopropyl ester is the most potent analog tested in reducing IOP, lowering the IOP 1.3 mm Hg below the level achieved by latanoprost. However, this derivative is also significantly more irritating to the eye than latanoprost. Uses: Scientific research. Group: Signaling pathways. CAS No. 130209-76-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116161A.
17-Phenyl trinor prostaglandin E2
17-Phenyl trinor PGE2 is a synthetic analog of PGE2. It is an EP1 and EP3 receptor agonist. Synonyms: 17-phenyl trinor PGE2; 17-phenyl-trinor-prostaglandin E2. Grades: ≥98%. CAS No. 38315-43-4. Molecular formula: C23H30O5. Mole weight: 386.5.
17-Phenyl-trinor-prostaglandin E2
17-Phenyl-trinor-prostaglandin E2 is a synthetic analog of PGE2 and an agonist at the EP1 and EP3 receptor (1). Prostaglandin E2(PGE2) regulates neuroinflammatory responses and is upregulated in brain injury by cyclooxygenase 2 (COX-?2) and membrane-bound PGE synthase. 17-Phenyl-trinor-prostaglandin E2 can be used to investigate inflammatory signaling pathways (2). Group: Biochemicals. Grades: Highly Purified. CAS No. 38315-43-4. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C23H30O5, Molecular Weight: 386.48. US Biological Life Sciences.
Worldwide
17-Phenyl trinor prostaglandin E2 ethyl amide
17-Phenyl trinor PGE2 ethyl amide is derived from 17-phenyl trinor PGE2, a synthetic analog of PGE2 that acts as an agonist of EP1 and EP3 receptors in mice (Ki = 14 and 3.7 nM, respectively) and EP1, EP3, and EP4 in rats (Ki = 25, 4.3, and 54 nM, respectively). Synonyms: 17-phenyl trinor PGE2 ethyl amide; (Z)-N-ethyl-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]-5-oxocyclopentyl]hept-5-enamide. Grades: ≥98%. CAS No. 1219032-20-8. Molecular formula: C25H35NO4. Mole weight: 413.6.
17-Phenyl trinor prostaglandin F2α 1,15-lactone
17-Phenyl trinor prostaglandin F2α 1,15-lactone is a metabolically stable analog of PGF2α with potent FP receptor agonist activity and well known intraocular pressure-reducing effects. Synonyms: 17-phenyl trinor PGF2α 1,15-lactone. Grades: ≥98%. Molecular formula: C23H30O4. Mole weight: 370.5.
17-Phenyl Trinor Prostaglandin F2α Methyl Amide
17-Phenyl Trinor Prostaglandin F2α-Methyl Amide is an analog of Bimatoprost, an antiglaucoma agent. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-methyl-5-heptenamide; [1R-[1α(Z), 2β(1E, 3S*), 3α, 5α]]-7-[3, 5-zdihydroxy-2-(3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl]-N-methyl-5-heptenamide; Bimatoprost Impurity 5. Grades: > 98%. CAS No. 155206-01-2. Molecular formula: C24H35NO4. Mole weight: 401.54.
17-Phenyl Trinor Prostaglandin F2α Methyl Amide
17-Phenyl Trinor Prostaglandin F2α Methyl Amide. Group: Biochemicals. Alternative Names: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-methyl-5-heptenamide; (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-pentenyl]cyclopentyl]-N-methyl-5-heptenamide; [1R-[1α(Z),2 β(1E, 3S*), 3α, 5α]]-7-[3, 5-zdihydroxy-2-(3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl]-N-methyl-5-heptenamide. Grades: Highly Purified. CAS No. 155206-01-2. Pack Sizes: 2.5mg. Molecular Formula: C24H35NO4, Molecular Weight: 401.54. US Biological Life Sciences.
17-HETE is a cytochrome P450 (CYP450) metabolite of arachidonic acid that has stereospecific effects on sodium transport in the kidney. Synonyms: (5Z,8Z,11Z,14Z,17R)-17-hydroxyicosa-5,8,11,14-tetraenoic acid. Grades: ≥98%. CAS No. 183509-24-2. Molecular formula: C20H32O3. Mole weight: 320.5.
17(R)-Resolvin D1
17(R)-Resolvin D1 is an exhibitor of a dose-dependent reduction in leukocyte infiltration. Group: Biochemicals. Grades: Highly Purified. CAS No. 528583-91-7. Pack Sizes: 10ug, 25ug. Molecular Formula: C22H32O5, Molecular Weight: 376.49. US Biological Life Sciences.
Worldwide
17(S)-HETE
17(S)-HETE is a cytochrome P450 (CYP450) metabolite of arachidonic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 183509-25-3. Pack Sizes: 25ug, 50ug. Molecular Formula: C20H32O3, Molecular Weight: 320.47. US Biological Life Sciences.
Worldwide
17(S)-HETE
17-HETE is a cytochrome P450 (CYP450) metabolite of arachidonic acid that has stereospecific effects on sodium transport in the kidney.17(S)-HETE inhibits proximal tubule ATPase activity by as much as 70% at a concentration of 2 μM. Synonyms: 17-hydroxyicosa-5,8,11,14-tetraenoic acid. Grades: ≥98%. CAS No. 183509-25-3. Molecular formula: C20H32O3. Mole weight: 320.5.
A metabolite of Dexamethasone. Group: Biochemicals. Alternative Names: 9-Fluoro-17-(formyloxy)-11-hydroxy-16-methyl-3-oxo--(11ß, 16a, 17a )-androsta-1,4- diene-17-carboxylic Acid. Grades: Highly Purified. CAS No. 473273-04-0. Pack Sizes: 5mg. US Biological Life Sciences.
17-Trifluoromethylphenyl trinor PGF2α bears an aromatic ring which is reminiscent of the trifluoromethyl-phenoxy ring of travoprost ((+)-fluprostenol isopropyl ester). As an ocular hypotensive agent, it would be expected that 17-trifluoromethylphenyl trinor PGF2α would act very much like the free acid of travoprost. Synonyms: 17-trifluoromethylphenyl trinor PGF2α; (2R,3S,4R)-2-Ethyl-4-hydroxy-3-{(3S)-3-hydroxy-5-[3-(trifluoromethyl)phenyl]pent-1-en-1-yl}cyclopentyl. Grades: ≥98%. CAS No. 221246-34-0. Molecular formula: C24H31O5F3. Mole weight: 456.5.
17- ( (Trimethylsilyl) ethynyl) -17- ( (trimethylsilyl) oxy) -2-isopropanol Gestodene is an intermediate in the synthesis of 2-Isopropanol Gestodene which is an impurity of Gestodene (G368250), an orally active steroid that exhibits progesterone (P755900) -like profile of activity. Gestodene have been used in combination with estrogen as an oral contraceptive. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C30H48O3Si2. US Biological Life Sciences.
17- ( (Trimethylsilyl) ethynyl) -17- ( (trimethylsilyl) oxy) Gestodene is an intermediate in the synthesis of 2-Isopropanol Gestodene which is an impurity of Gestodene (G368250), an orally active steroid that exhibits progesterone (P755900) -like profile of activity. Gestodene have been used in combination with estrogen as an oral contraceptive. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 50mg. Molecular Formula: C27H42O2Si2. US Biological Life Sciences.
18:0,18:1 PS sodium is a lipid component of synaptic vesicles and cholesterol, which can be used for metabolic research [1]. Uses: Scientific research. Group: Natural products. CAS No. 321883-23-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148978.
1-stearoyl-2-docosahexaenoyl-sn-glycerol In biochemical signaling, diacylglycerol (DAG) functions as a second messenger signaling lipid and is a product of the hydrolysis of the phospholipid PIP2(phosphatidylinositol bisphosphate) by the enzyme phospholipase C (PLC) (a membrane-bound enzyme) that, through the same reaction, produces inositol trisphosphate (IP3). Group: Neutral lipids. Alternative Names: 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol DG(18:0/22:6(4Z, 7Z, 10Z, 13Z, 16Z, 19Z)/0:0). CAS No. 65886-80-8. Molecular formula: C43H72O5. Mole weight: 669.029. Purity: >99%. Catalog: ACM65886808.
The biomedical product, 18:0(2R-OH) Sulfo GalCer Ammonium salt, is a potent agent in the fight against cancer. Specifically designed as an activator in immunotherapy, this mighty compound provides a means to target and treat a range of cancers including melanoma, leukemia, and lymphoma. With a molecular conformation that allows for binding to natural killer T cells, clinical research has demonstrated a positive immune response against cancer cells. Synonyms: 3-O-sulfo-D-galactosyl-β-1,1'-N-[2''(R)-hydroxystearoyl]-D-erythro-sphingosine (ammonium salt); Ammonium (2S,3R,4E)-3-hydroxy-2-{[(2R)-2-hydroxyoctadecanoyl]amino}-4-octadecen-1-yl 3-O-sulfonato-β-D-threo-hexopyranoside. Grades: >99%. CAS No. 2260670-26-4. Molecular formula: C42H84N2O12S. Mole weight: 841.19.
18:0(2S-OH) Sulfo GalCer Ammonium salt, a synthetic compound employed in biomedical research, has the capacity to serve as a potent therapeutic agent for the treatment of various malignancies- specifically leukemia and lymphoma. Boasting versatile therapeutic potential, it has been shown to exhibit anti-inflammatory properties, and has exciting potential for the treatment of autoimmune diseases like multiple sclerosis. With its staggering attributes as a sulfo glycolipid, this intriguing compound holds tremendous promise and warrants thorough exploration in the realm of drug development. Synonyms: 3-O-sulfo-D-galactosyl-β-1,1'-N-[2''(S)-hydroxystearoyl]-D-erythro-sphingosine (ammonium salt); Ammonium (2S,3R,4E)-3-hydroxy-2-{[(2S)-2-hydroxyoctadecanoyl]amino}-4-octadecen-1-yl 3-O-sulfonato-β-D-threo-hexopyranoside; Octadecanamide, 2-hydroxy-N-[(1S,2R,3E)-2-hydroxy-1-[[(3-O-sulfo-β-D-threo-hexopyranosyl)oxy]methyl]-3-heptadecen-1-yl]-, ammonium salt, (2S)-. Grades: >99%. CAS No. 2260670-28-6. Molecular formula: C42H84N2O12S. Mole weight: 841.19.
18:0 mPEG2000 PE sodium can be used for the preparation of stabilized nucleic acid-lipid particllipid particles (SNALPs). SNALPs represent some of the earliest and best functional siRNA-ABC nanoparticles described [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: DSPE-mPEG2000 sodium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] sodium. CAS No. 247925-28-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112760.
DSPA (1,2-distearoyl-sn-glycero-3-phosphate) is a phospholipid containing a phosphatidic acid head group and 18:0 fatty acids at the sn-1 and sn-2 positions of the glycerol backbone. DSPA has been used to study the dynamics of model lipid bilayers via its negative charge. Uses: The study of lipid bilayers' dynamics. Synonyms: 1,2-distearoyl-sn-glycero-3-phosphate (sodium salt); DSPA-Na; Sodium (R)-2,3-bis(stearoyloxy)propyl hydrogenphosphate. Grades: ≥98%. CAS No. 108321-18-2. Molecular formula: C39H76NaO8P. Mole weight: 726.98.
An analogue of Buprenorphine (B689570) which displays high affinity and selectivity for μ-opioid receptors. It acts as an antinociceptive agent and potent analgesic. Group: Biochemicals. Grades: Highly Purified. CAS No. 155203-05-7. Pack Sizes: 250ug, 1mg. Molecular Formula: C29H39NO4. US Biological Life Sciences.