A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Acid Yellow 3, C.I. Group: Biochemicals. Grades: Highly Purified. CAS No. 8004-92-0. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C18H9NNa2O8S2. US Biological Life Sciences.
Worldwide
ACID YELLOW 40
ACID YELLOW 40. Uses: Designed for use in research and industrial production. Additional or Alternative Names: acidyellow40(c.i.18950);benzenesulfonicacid,5-chloro-2-[4,5-dihydro-3-methyl-4-[[4-[[(4-methylphenyl);POLAR YELLOW;ACID YELLOW 40;CI 18950;Acid Yellow 40 (C.I.);C.I. Acid Yellow 40;sodium 5-chloro-2-(5-hydroxy-3-methyl-4-(4-((4-methylphenyl)sulphonyloxy). Product Category: Acid Dyes. CAS No. 6372-96-9. Molecular formula: C23H18ClN4NaO7S2. Mole weight: 584.98. Product ID: ACM6372969. Alfa Chemistry ISO 9001:2015 Certified. Categories: DTXSID70884278.
Acid Yellow 42
Acid Yellow 42. Uses: Designed for use in research and industrial production. Product Category: Acid Dyes. CAS No. 6375-55-9. Product ID: ACM6375559. Alfa Chemistry ISO 9001:2015 Certified. Categories: Acid Yellow 23.
Acid Yellow 44
Acid Yellow 44. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ACID YELLOW 44;CI ACID YELLOW 44;Disodium 5-[[1,3-dioxo-1-(phenylamino)butan-2-yl]azo]-2-[4-[[1,3-dioxo-1-(phenylamino)butan-2-yl]azo]-5-methyl-2-sulfonatophenyl]-4-methylbenzenesulfonate;Acid Yellow 6G;disodium 5,5'-dimethyl-4,4'-bis[[2-oxo-1-[(phenylam. Product Category: Acid Dyes. CAS No. 2429-76-7. Molecular formula: C34H30N6Na2O10S2. Mole weight: 792.75. Density: g/cm³. Product ID: ACM2429767. Alfa Chemistry ISO 9001:2015 Certified.
Acid Yellow 49
C.I. Acid Yellow 49, also known as C.I. 47005, is an azo dye with a bright yellow color. It is used as a dye in various industries, such as the food and textile industries, and has been used in scientific research to study various biochemical and physiological effects. Uses: C.i. acid yellow 49 acid yellow 49 has been used in scientific research to study a variety of biochemical and physiological effects. for example, it has been used to study the effects of oxidative stress on cells, as well as the effects of various drugs on cells. it has also been used to study the effects of environmental contaminants on cells, including the effects of heavy metals and organic pollutants. Additional or Alternative Names: C.I. Acid Yellow 49;Benzenesulfonic acid, 4-((5-amino-3-methyl-1-phenyl-1H-pyrazol-4-yl)azo)-2,5-dichloro-. Product Category: Acid Dyes. Appearance: Powder. CAS No. 12239-15-5. Molecular formula: C16H13Cl2N5O3S. Mole weight: 426.28. IUPACName: 4-[(5-amino-3-methyl-1-phenylpyrazol-4-yl)diazenyl]-2,5-dichlorobenzenesulfonic acid. Canonical SMILES: CC1=NN(C(=C1N=NC2=CC(=C(C=C2Cl)S(=O)(=O)O)Cl)N)C3=CC=CC=C3. Density: 1.6±0.1 g/mL. ECNumber: 235-473-4. Product ID: ACM12239155-2. Alfa Chemistry ISO 9001:2015 Certified. Categories: 4-[(5-amino-3-methyl-1-phenyl-1h-pyrazol-4-yl)azo]-2,5-dichlorobenzenesulphonic acid.
Acid Yellow 4R
Acid Yellow 4R. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Acid Yellow 4R;dihydrogen bis[2-[[5-(aminosulphonyl)-2-hydroxyphenyl]azo]-3-oxo-N-phenylbutyramidato(2-)]cobaltate(2-);AcidyellowNW;Cobaltate(2-), bis2-5-(aminosulfonyl)-2-(hydroxy-.kappa.O)phenylazo-.kappa.N1-3-(oxo-.kappa.O)-N-phenylbutanamidato(2-)-. Product Category: Acid Dyes. CAS No. 12715-61-6. Molecular formula: C16H16N4O5S. Mole weight: 376.38. Density: g/cm³. Product ID: ACM12715616. Alfa Chemistry ISO 9001:2015 Certified.
Acid Yellow 61
Acid Yellow 61. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Acid Yellow 61;sodium 2,5-dichloro-4-[4-[[2-[(ethylphenylamino)sulphonyl]phenyl]azo]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]benzenesulphonate;Benzenesulfonic acid, 2,5-dichloro-4-4-2-(ethylphenylamino)sulfonylphenylazo-4,5-dihydro-3-methyl-5-oxo-1H-. Product Category: Acid Dyes. CAS No. 12217-38-8. Molecular formula: C24H20Cl2N5NaO6S2. Mole weight: 632.46. Product ID: ACM12217388. Alfa Chemistry ISO 9001:2015 Certified.
Acid yellow 65
Acid yellow 65. Uses: Designed for use in research and industrial production. Additional or Alternative Names: EINECS 229-071-8; ACID YELLOW 65. Product Category: Heterocyclic Organic Compound. Appearance: Brown Powder. CAS No. 6408-90-8. Molecular formula: C25H19N4NaO8S2. Mole weight: 590.56. Purity: 0.96. IUPACName: sodium 2-[4-[4-(benzenesulfonyloxy)-3-methylphenyl]diazenylanilino]-5-nitrobenzenesulfonate. Canonical SMILES: CC1=C(C=CC(=C1)N=NC2=CC=C(C=C2)NC3=C(C=C(C=C3)[N+](=O)[O-])S(=O)(=O)[O-])OS(=O)(=O)C4=CC=CC=C4.[Na+]. ECNumber: 229-071-8. Product ID: ACM6408908. Alfa Chemistry ISO 9001:2015 Certified. Categories: DTXSID30884299.
Acid Yellow 72
Acid Yellow 72. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Acid Yellow 72;sodium 2,5-dichloro-4-[4-[(4-dodecylphenyl)azo]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]benzenesulphonate;Benzenesulfonic acid, 2,5-dichloro-4-[4-[(4-dodecylphenyl)azo]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]-, sodium salt;Benzenes. Product Category: Acid Dyes. CAS No. 52584-47-1. Molecular formula: C28H35Cl2N4NaO4S. Mole weight: 617.56. Density: g/cm³. Product ID: ACM52584471. Alfa Chemistry ISO 9001:2015 Certified. Categories: Acid Yellow 23.
Acid Yellow 79
Acid Yellow 79. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Acid Yellow 79;C.I. Acid yellow 79;Acid Yellow 4GL;Best Acid Milling Yellow 4GL;Everacid Yellow 4G;Kenamide Yellow K4G;Levaderm Lemon;Polar Yellow 4G. Product Category: Acid Dyes. CAS No. 12220-70-1. Molecular formula: C47H40N10Na2O12S4. Mole weight: 1111.11. Product ID: ACM12220701. Alfa Chemistry ISO 9001:2015 Certified. Categories: Acid Yellow 73.
Acid Yellow 99
Acid Yellow 99. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Acid complex yellow GR. Appearance: Yellow to brown powder. CAS No. 10343-58-5. Molecular formula: C16H13CrN4NaO8S. Mole weight: 496.35. Purity: 0.4. Product ID: ACM10343585. Alfa Chemistry ISO 9001:2015 Certified.
Ac-IEPD-AFC
Ac-IEPD-AFC. Group: Biochemicals. Grades: Purified. CAS No. 1135417-31-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Ac-IEPD-AFC
Ac-IEPD-AFC is a peptide whose sequence is preferred recognition motif for the serine protease granzyme B. It is a fluorogenic substrate. Synonyms: IEPD; N-Acetyl-Ile-Glu-Pro-Asp-(7-amino-4-trifluoromethylcoumarin); Ac-Ile-Glu-Pro-Asp-7-Amino-4-trifluoromethylcoumarin. Grades: ≥95%. CAS No. 1135417-31-0. Molecular formula: C32H38F3N5O11. Mole weight: 725.67.
Ac-IETD-AFC
Ac-IETD-AFC is a fluorogenic substrate for caspase-8 and caspase-3. Caspase activity can be quantified by fluorescent detection of free AFC (7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm. Synonyms: N-Acetyl-Ile-Glu-Thr-Asp-7-amino-4-Trifluoromethylcoumarin; N-acetyl-L-isoleucyl-L-α-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine. Grades: ≥95%. CAS No. 211990-57-7. Molecular formula: C31H38F3N5O12. Mole weight: 729.7.
Ac-IETD-CHO trifluoroacetate salt
Ac-IETD-CHO is an inhibitor of caspase-8 (IC50 = 5 nM). It inhibits fluticasone propionate-induced increases in apoptosis in peripheral blood T-cells isolated from patients with asthma when used at a concentration 60 μM. Synonyms: Ac-Ile-Glu-Thr-Asp-CHO; Caspase-8 Inhibitor. Grades: ≥95%. CAS No. 191338-86-0. Molecular formula: C21H34N4O10·xCF3COOH. Mole weight: 502.52.
Acifluorfen
Acifluorfen, a protoporphyrinogen oxidase (PROTOX) inhibitor herbicide, promotes the accumulation of protoporphyrin IX (PPIX), and induces tumors in the rodent liver. Acifluorfen causes strong photooxidative destruction of pigments and lipids in sensitive plant species [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 50594-66-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-128075.
Acifluorfen Methyl Ester
Acifluorfen Methyl Ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: methylacifluorfen;ACIFLUORFEN METHYL ESTER STANDARD;MC-10108. Product Category: Heterocyclic Organic Compound. CAS No. 50594-67-7. Molecular formula: C15H9ClF3NO5. Mole weight: 375.685. Product ID: ACM50594677. Alfa Chemistry ISO 9001:2015 Certified.
Acifran
Acifran is a nicotinic acid receptor agonist with hypolipidemic effects, which shows higher potency than nicotinic acid and clofibrate. It is a potent and full agonist at the human orphan GPCR HM74A/GPR109A and GPR109B. It reduces circulating LDL-cholesterol and serum triglycerides in vivo without affecting liver enzymes or liver weight. Synonyms: AY 25712; AY-25712; AY25712; 4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid; (±)-Acifran; Reductol. Grades: ≥99% by HPLC. CAS No. 72420-38-3. Molecular formula: C12H10O4. Mole weight: 218.21.
Acifran
Acifran (AY 25712), an antihyperlipidemic agent, is an orally active agonist of GPR109A (HM74A) and GPR109B, the high and low affinity receptors for Niacin [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AY 25712. CAS No. 72420-38-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-107579.
Acifran
Acifran. Group: Biochemicals. Grades: Purified. CAS No. 72420-38-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Ac-ile-tyr(po3h2)-gly-glu-phe-nh2
Ac-ile-tyr(po3h2)-gly-glu-phe-nh2. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AC-ILE-TYR(PO3H2)-GLY-GLU-PHE-NH2;AC-IY(PO3H2)GEF-NH2;AC-IPYGEF-NH2;P60C-SRC SUBSTRATE II, PHOSPHORYLATED;SRC SUBSTRATE II, PHOSPHORYLATED. Product Category: Heterocyclic Organic Compound. CAS No. 284660-72-6. Molecular formula: C30H41N6O10P. Mole weight: 676.65. Product ID: ACM284660726. Alfa Chemistry ISO 9001:2015 Certified.
Acipimox
Acipimox (K-9321), a nicotinic acid analogue, is an antilipolytic compound. Acipimox stimulates leptin releas, inhibits lipolysis and suppresses systemic levels of free fatty acids (FFAs) and improves insulin sensitivity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: K-9321. CAS No. 51037-30-0. Pack Sizes: 50 mg; 100 mg. Product ID: HY-B0283.
Acipimox
Acipimox (trade name Olbetam in Europe) is a niacin derivative used as a hypolipidemic agent. It is used in low doses and may have less marked adverse effects, although it is unclear whether the recommended dose is as effective as are standard doses of nicotinic acid. Acipimox inhibits the production of triglycerides by the liver and the secretion ofVLDL cholesterol, which leads indirectly to a modest reduction in LDL and increase in HDL cholesterol. Synonyms: Acipimox; K-9321; K9321; K 9321; Olbemox; Olbetam. Grades: >98%. CAS No. 51037-30-0. Molecular formula: C6H6N2O3. Mole weight: 154.12.
Acipimox
Antilipemic. Group: Biochemicals. Alternative Names: 5-Methyl-2-pyrazinecarboxylic Acid 4-Oxide; 5- methyl pyrazinecarboxylic Acid 4-Oxide; K 9321; Olbemox; Olbetam. Grades: Highly Purified. CAS No. 51037-30-0. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Acipimox-[13C2,15N2]
Acipimox-[13C2,15N2] is the labelled analogue of Acipimox, which is a niacin derivative used as a hypolipidemic agent. Synonyms: Acipimox-13C2,15N2; 5-Methyl-2-pyrazinecarboxylic Acid 4-Oxide-13C2,15N2; 5-Methylpyrazinecarboxylic Acid 4-Oxide-13C2,15N2; Olbemox-13C2,15N2; Olbetam-13C2,15N2. Grades: 95% by HPLC; 98% atom 13C, 98% atom 15N. Molecular formula: C4[13C]2H6[15N]2O3. Mole weight: 158.10.
acireductone dioxygenase [iron(II)-requiring]
Requires iron(II). If Ni2+ is bound instead of iron(II), the reaction catalysed by EC 1.13.11.53, acireductone dioxygenase (Ni2+-requiring), occurs instead. The enzyme from the bacterium Klebsiella oxytoca (formerly Klebsiella pneumoniae) ATCC strain 8724 is involved in the methionine salvage pathway. Group: Enzymes. Synonyms: ARD'; 2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase (ambiguous); acireductone dioxygenase (ambiguous); E-2'; E-3 dioxygenase. Enzyme Commission Number: EC 1.13.11.54. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0573; acireductone dioxygenase [iron(II)-requiring]; EC 1.13.11.54; ARD'; 2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase (ambiguous); acireductone dioxygenase (ambiguous); E-2'; E-3 dioxygenase. Cat No: EXWM-0573.
acireductone dioxygenase (Ni2+-requiring)
Requires Ni2+. If iron(II) is bound instead of Ni2+, the reaction catalysed by EC 1.13.11.54, acireductone dioxygenase [iron(II)-requiring], occurs instead. The enzyme from the bacterium Klebsiella oxytoca (formerly Klebsiella pneumoniae) ATCC strain 8724 is involved in the methionine salvage pathway. Group: Enzymes. Synonyms: ARD; 2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase (ambiguous); acireductone dioxygenase (ambiguous); E-2. Enzyme Commission Number: EC 1.13.11.53. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0572; acireductone dioxygenase (Ni2+-requiring); EC 1.13.11.53; ARD; 2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase (ambiguous); acireductone dioxygenase (ambiguous); E-2. Cat No: EXWM-0572.
acireductone synthase
This bifunctional enzyme first enolizes the substrate to form the intermediate 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate, which is then dephosphorylated to form the acireductone 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one. The acireductone represents a branch point in the methione-salvage pathway as it is used in the formation of formate, CO and 3-(methylthio)propanoate by EC 1.13.11.53 [acireductone dioxygenase (Ni2+-requiring)] and of formate and 4-methylthio-2-oxobutanoate either by a spontaneous reaction under aerobic conditions or by EC 1.13.11.54 {acireductone dioxygenase [iron(II)-requiring]}. Group: Enzymes. Synonyms: E1; E-1 enolase-phosphatase. Enzyme Commission Number: EC 3.1.3.77. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3682; acireductone synthase; EC 3.1.3.77; E1; E-1 enolase-phosphatase. Cat No: EXWM-3682.
Acitretin
Acitretin is a second generation retinoid used for psoriasis. Synonyms: Ro 10-1670; Ro-10-1670; Ro10-1670; Ro 10-1670/000; U0279; Acitretin; Soriatane; Etretin; Neotigason. Grades: >98%. CAS No. 55079-83-9. Molecular formula: C21H26O3. Mole weight: 326.43.
Acitretin
Acitretin. Group: Biochemicals. Alternative Names: 9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid. Grades: Highly Purified. CAS No. 55079-83-9. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C21H26O3. US Biological Life Sciences.
Worldwide
Acitretin
Acitretin (Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis. Acitretin also can be used for the research of Alzheimers disease [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 10-1670. CAS No. 55079-83-9. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-B0107.
A synthetic retinoid which is the major metabolite of etretinate. Group: Biochemicals. Alternative Names: (all-E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic Acid; Neotigason, Soriatane. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Acitretin Related Compound A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Acitretin sodium
Acitretin sodium is a second-generation, systemic retinoid that has been used in the treatment of psoriasis. It can be considered one of the treatments of choice for pustular and erythrodermic psoriasis. However, the efficacy of acitretin sodium as a monotherapy for plaque psoriasis is less, although it is often used in combination therapy with other systemic psoriasis therapies, especially ultraviolet B or psoralen plus ultraviolet A phototherapy, to increase efficacy. Such combination treatments may potentially minimise toxicity by using lower doses of each of the two agent. Synonyms: Ro 10-1670 sodium; Soriatane sodium. Grades: >98%. CAS No. 925701-88-8. Molecular formula: C21H25NaO3. Mole weight: 348.41.
Acivicin
Acivicin is an isoxazole antibiotic isolated from Streptomyces. sviceus. Acivicin is a glutamine analog that irreversibly inhibits glutamine-dependent amidotransferases involved in nucleotide and amino acid biosynthesis (Kis = 10 and 560 μM for anthranilate synthase and glutamate synthase, respectively) as a potent antitumor antibiotic that induces apoptosis in human lymphoblastoid cells. Acivicin is an inhibitor of GGT used for solid tumor research. Uses: Protease inhibitor. Synonyms: (S-(R*,R*))-4,5-Dihydro-alpha-amino-3-chloro-5-isoxazoleacetic acid; (alpha-S,5S)-alpha-Amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid; (alphaS,5S)-alpha-Amino-3-chlor-4,5-dihydro-5-isoxazolylessigsaeure. Grades: ≥98% by HPLC. CAS No. 42228-92-2. Molecular formula: C5H7ClN2O3. Mole weight: 178.57.
Acivicin
Acivicin (AT-125), a natural product produced by Streptomyces sviceus is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin can across the blood-brain barrier and has anti-cancer, anti-parasitic properties. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (alpha-s,5s)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleaceticacid;(s-(r*,r*))-4,5-dihydro-alpha-amino-3-chloro-5-isoxazoleaceticacid;4,5-dihydro-alpha-amino-3-chloro-,(s-(r*,r*))-5-isoxazoleaceticaci;acivicine;antibioticat125;nsc-163501;AT-125;ALPHA-AMINO-3-CHLORO-4,5-DIHYDRO-5-ISOXAZOLEACETIC ACID. Product Category: Inhibitors. Appearance: Solid. CAS No. 42228-92-2. Molecular formula: C5H7ClN2O3. Mole weight: 178.57. Canonical SMILES: ClC1=NO[C@@]([C@H](N)C(O)=O)([H])C1. Product ID: ACM42228922. Alfa Chemistry ISO 9001:2015 Certified.
Acivicin
Acivicin (AT-125), a natural product produced by Streptomyces sviceus is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin can across the blood-brain barrier and has anti-cancer, anti-parasitic properties [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: AT-125; U-42126. CAS No. 42228-92-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W016586.
Acivicin
Azaserine and Acivicin are classical and irreversible inhibitors of γ -Glutamyl transpeptidase. Group: Biochemicals. Alternative Names: (αS,5S)-. Grades: Highly Purified. CAS No. 42228-92-2. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Acivicin hydrochloride
Acivicin hydrochloride (AT-125 hydrochloride), a natural product produced by Streptomyces sviceus , is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin hydrochloride can across the blood-brain barrier and has anti-cancer, anti-parasitic properties [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: AT-125 hydrochloride; U-42126 hydrochloride. CAS No. 161922-40-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W016586A.
A cell-permeable furopyrimidine that acts as a potent, ATP-binding site-targeting, Ack1-selective inhibitor (IC50 = 22nM) and effectively prevents receptor-mediated Ack1 activation (by >90% in MEF & LAPC4 cultures; 16h 800nM), while exhibiting much reduced potency against Lyn, Lck, Abl1 and BTK (IC50 ≥346.7nM) and no inhibitory activity toward 25 other kinases. Shown to completely inhibit EGF-induced, but not androgen DHT- (dihydrotestosterone) stimulated, AR transcription activity in serum- and androgen-deprived prostate cancer LAPC4 cutlures. Effectively inhibits androgen-independent LNCaP prostate cancer growth both in vitro (by 60%; 72h 8uM) and in castrated mice in vivo (4mg/kg/96h injections on day 7/11/15/19/23/27 post tumor transplant). Group: Biochemicals. Grades: Highly Purified. CAS No. 873305-35-2. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Aclacinomycin A
Aclacinomycin A (Aclarubicin) is an orally active and potent anthracycline antitumor antibiotic. Aclacinomycin A is an inhibitor of topoisomerase I and II. Aclacinomycin A inhibits synthesis of nucleic acid, especially RNA. Aclacinomycin A might inhibit the 26S protease complex as well as the ubiquitin-ATP-dependent proteolysis [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Aclarubicin. CAS No. 57576-44-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N2306.
aclacinomycin-A oxidase
A flavoprotein (FAD). This bifunctional enzyme is a secreted flavin-dependent enzyme that is involved in the modification of the terminal sugar residues in the biosynthesis of aclacinomycins. The enzyme utilizes the same active site to catalyse the oxidation of the rhodinose moiety of aclacinomycin N to the cinerulose A moiety of aclacinomycin A (cf. EC 1.1.3.45) and the oxidation of the latter to the L-aculose moiety of aclacinomycin Y. Group: Enzymes. Synonyms: AknOx (ambiguous); aclacinomycin oxidoreductase (ambiguous). Enzyme Commission Number: EC 1.3.3.14. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1375; aclacinomycin-A oxidase; EC 1.3.3.14; AknOx (ambiguous); aclacinomycin oxidoreductase (ambiguous). Cat No: EXWM-1375.
Aclacinomycin B
Aclacinomycin B is an anthrone antitumor antibiotic isolated from Streptomyces galilaeus. Synonyms: Antibiotic MA 144B1; Aclarubicin B. CAS No. 57596-79-9. Molecular formula: C42H51NO15. Mole weight: 809.85.
Aclacinomycin HCl
Aclacinomycin HCl. Group: Biochemicals. Alternative Names: Aclarubicin HCl. Grades: Highly Purified. CAS No. 75443-99-1. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C42H53NO15·HCl. US Biological Life Sciences.
Worldwide
aclacinomycin methylesterase
The enzyme is involved in the modification of the aklavinone skeleton in the biosynthesis of anthracyclines in Streptomyces species. Group: Enzymes. Synonyms: RdmC; aclacinomycin methyl esterase. Enzyme Commission Number: EC 3.1.1.95. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3524; aclacinomycin methylesterase; EC 3.1.1.95; RdmC; aclacinomycin methyl esterase. Cat No: EXWM-3524.
aclacinomycin-N oxidase
A flavoprotein (FAD). This bifunctional enzyme is a secreted flavin-dependent enzyme that is involved in the modification of the terminal sugar residues in the biosynthesis of aclacinomycins. The enzyme utilizes the same active site to catalyse the oxidation of the rhodinose moiety of aclacinomycin N to the cinerulose A moiety of aclacinomycin A and the oxidation of the latter to the L-aculose moiety of aclacinomycin Y (cf. EC 1.3.3.14, aclacinomycin A oxidase). Group: Enzymes. Synonyms: AknOx (ambiguous); aclacinomycin oxidoreductase (ambiguous). Enzyme Commission Number: EC 1.1.3.45. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0418; aclacinomycin-N oxidase; EC 1.1.3.45; AknOx (ambiguous); aclacinomycin oxidoreductase (ambiguous). Cat No: EXWM-0418.
aclacinomycin-T 2-deoxy-L-fucose transferase
The enzyme, isolated from the bacterium Streptomyces galilaeus, is involved in the biosynthesis of other aclacinomycins. Also acts on idarubicin. It will slowly add a second 2-deoxy-L-fucose unit to aclacinomycin S in vitro. Group: Enzymes. Synonyms: AknK. Enzyme Commission Number: EC 2.4.1.327. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2564; aclacinomycin-T 2-deoxy-L-fucose transferase; EC 2.4.1.327; AknK. Cat No: EXWM-2564.
Aclacinomycin Y
Aclacinomycin Y is an anthrone antitumor antibiotic isolated from Streptomyces galilaeus. CAS No. 66789-14-8. Molecular formula: C42H51NO15. Mole weight: 809.85.
Aclame
Aclame is an intense sweetener that is about 2000 times sweeter than sucrose. Synonyms: L-α-Aspartyl-N-(2,2,4,4-tetramethyl-3-thietanyl)-D-alaninamide; Alitame; L-aspartyl-D-alanine-N-(2,2,4,4-tetramethylthietan-3-yl)amide; 3-(L-aspartyl-D-alaninamido)-2,2,4,4-tetramethylthietane; (S)-3-Amino-4-oxo-4-(((R)-1-oxo-1-((2,2,4,4-tetramethylthietan-3-yl)amino)propan-2-yl)amino)butanoic acid; (S)-3-((R)-1-(2,2,4,4-Tetramethylthietan-3-ylcarbamoyl)ethylcarbamoyl)-3-aminopropanoic acid. Grades: 95%. CAS No. 80863-62-3. Molecular formula: C14H25N3O4S. Mole weight: 331.43.
Aclarubicin A
Aclarubicin is an oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces galilaeus. It intercalates into DNA and interacts with topoisomerases I and II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. It is antagonistic to other agents that inhibit topoisomerase II, such as etoposide, teniposide and amsacrine. It has potent antineoplastic activity. It is used in the treatment of cancer. It can induce histone eviction from chromatin upon intercalation. It has been listed. Uses: Aclarubicin has potent antineoplastic activity. it is used in the treatment of cancer. it can induce histone eviction from chromatin upon intercalation. Synonyms: 11-Dioxo-4-((2,3,6-trideoxy-4-o-(2,6-dideoxy-4-o-((2r-trans)-tetrahydro-6-met;1-naphthacenecarboxylicacid,2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6;(1R,2R,4S)-methyl 4-(((2R,5S,6S)-4-(dimethylamino)-5-(((2S,4S,5S,6S)-4-hydroxy-6-methyl-5-(((2R,6S). Grades: ≥95%. CAS No. 57576-44-0. Molecular formula: C42H53NO15. Mole weight: 811.88.
Aclarubicin hydrochloride
Aclarubicin is an oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces galilaeus. Aclarubicin intercalates into DNA and interacts with topoisomerases I and II, thereby inhibiting replication and repair of DNA and RNA, and protein synthesis. Aclarubicin is antagonistic to other agents that inhibit topoisomerase II, such as etoposide, teniposide and amsacrine. This agent is less cardiotoxic than doxorubicin and daunorubicin. Uses: Antibiotics, antineoplastic. Synonyms: Aclacinon; Aclaplastin; Aclacinomycin A Hydrochloride; Aclarubicin HCl; Aclarubicina Clorhidrato [Spanish]. Grades: >98%. CAS No. 75443-99-1. Molecular formula: C42H54ClNO15. Mole weight: 848.33.
Ac-LEHD-AFC
Ac-LEHD-AFC is a fluorogenic substrate for caspase-4, 5 and 9. Synonyms: N-acetyl-L-leucyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine; N-Acetyl-Leu-Glu-His-Asp-7-amino-4-Trifluoromethylcoumarin; Caspase-9 substrate; L-α-Asparagine, N-acetyl-L-leucyl-L-α-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-; (4S,7S,10S,13S)-10-((1H-imidazol-5-yl)methyl)-7-(2-carboxyethyl)-4-isobutyl-2,5,8,11-tetraoxo-13-((2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl)carbamoyl)-3,6,9,12-tetraazapentadecan-15-oic acid. Grades: ≥95%. CAS No. 210345-03-2. Molecular formula: C33H38F3N7O11. Mole weight: 765.69.
Ac-LEHD-AFC
Ac-LEHD-AFC. Group: Biochemicals. Grades: Purified. CAS No. 210345-03-2. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Ac-LEHD-AMC
Ac-LEHD-AMC is a fluorogenic substrate for caspase-9. Ac-LEHD-AMC is cleaved by caspase-9 to release the fluorescent moiety AMC, which can be used to quantify caspase-9 activity. Synonyms: N-acetyl-L-leucyl-L-α-glutamyl-L-histidyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine. Grades: ≥95%. CAS No. 292633-16-0. Molecular formula: C33H41N7O11. Mole weight: 711.7.
Aclerastide
Aclerastide is an angiotensin receptor agonist, potentially used to treat tissue regeneration in diabetic ulcers and scars. Synonyms: Norleu3-a(1-7); UNII-YYD6UT8T47; Asp-arg-nle-tyr-ile-his-pro; DSC127; DSC-127; USB-001. Grades: ≥98% by HPLC. CAS No. 227803-63-6. Molecular formula: C42H64N12O11. Mole weight: 913.0406.
Ac-LETD-AFC
Ac-LETD-AFC is a fluorogenic substrate for caspase-8. Caspase activity can be quantified by fluorescent detection of free AFC (7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm. Synonyms: N-Acetyl-Leu-Glu-Thr-Asp-7-amino-4-Trifluoromethylcoumarin; N-acetyl-L-leucyl-L-α-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine. Grades: ≥95%. CAS No. 210345-02-1. Molecular formula: C31H38F3N5O12. Mole weight: 729.7.
Ac-Leu-Arg-AMC
Ac-Leu-Arg-AMC is a fluorogenic peptide substrate. Synonyms: L-Argininamide, N-acetyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-. Grades: ≥95%. CAS No. 929621-79-4. Molecular formula: C24H34N6O5. Mole weight: 486.56.
Ac-leu-glu-thr-asp-afc
Ac-leu-glu-thr-asp-afc. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AC-LEU-GLU-THR-ASP-7-AMINO-4-TRIFLUORO-METHYLCOUMARIN;AC-LEU-GLU-THR-ASP-AFC;AC-LETD-AFC;N-ACETYL-LEU-GLU-THR-ASP 7-AMIDO-4-TRIFLUOROMETHYLCOUMARIN. Product Category: Heterocyclic Organic Compound. CAS No. 210345-02-1. Molecular formula: C31H38F3N5O12. Mole weight: 729.65. Product ID: ACM210345021. Alfa Chemistry ISO 9001:2015 Certified.
Ac-LEVD-CHO trifluoroacetate salt
Ac-LEVD-CHO is a caspase-4 inhibitor. It inhibits IL-1α expression and secretion and caspase-4 activation induced by the T. denticola periodontal pathogen surface protein Td92 in human gingival fibroblasts when used at a concentration of 30 μM. Synonyms: Ac-Leu-Glu-Val-Asp-CHO; Caspase-4 Inhibitor I. Grades: ≥95%. CAS No. 402832-01-3. Molecular formula: C22H36N4O9·xCF3COOH. Mole weight: 500.5.
Acl I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 2-fold overdigestion with enzyme 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U. AA↑CGTT TTGC↓AA. Activity: 3000-5000u.a./ml. Appearance: 10 X SE-buffer Y, BSA. Storage: -20°C. Form: Liquid. Source: Acinetobacter calcoaceticus. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 0.05% Triton X-100; 50% glycerol. Cat No: RE-1009EN.
Aclidinium Bromide
Aclidinium Bromide(LAS 34273; LAS-W 330) is a long-acting, inhaled muscarinic antagonist as a maintenance treatment for chronic obstructive pulmonary disease (COPD). Synonyms: trade name: Eklira Genuair; Tudorza Genuair; Bretaris Genuair. Grades: 0.98. CAS No. 320345-99-1. Molecular formula: C26H30BrNO4S2. Mole weight: 564.553.
Aclidinium Bromide
Aclidinium Bromide is a novel long-acting antimuscarinic bronchodilator in phase II clinical trials for the treatment of chronic obstructive pulmonary disease. Group: Biochemicals. Alternative Names: (3R)-3-[(2-Hydroxy-2, 2-di-2-thienylacetyl)oxy]-1-(3-phenoxypropyl)-1-azoniabicyclo[2. 2. 2]octane Bromide; (3R)-(2-Hydroxy-2, 2-dithien-2-ylacetoxy)-1-(3-phenoxypropyl)-1-azoniabicyclo[2. 2. 2]octane Bromide; Aclidinium Bromide; Genuair; LAS 34273; LAS-W 330. Grades: Highly Purified. CAS No. 320345-99-1. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Aclidinium Bromide
Aclidinium Bromide (LAS 34273; LAS-W 330) is a long-acting, inhaled muscarinic antagonist. Aclidinium Bromide has the potential for chronic obstructive pulmonary disease (COPD) research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LAS 34273; LAS-W 330. CAS No. 320345-99-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14144.
Aclidinium-d5 Bromide
Aclidinium-d5 Bromide. Group: Biochemicals. Alternative Names: (3R)-3-[(2-Hydroxy-2, 2-di-2-thienylacetyl)oxy]-1-(3-phenoxypropyl)-1-azoniabicyclo[2. 2. 2]octane-d5 Bromide; (3R)-(2-Hydroxy-2, 2-dithien-2-ylacetoxy)-1-(3-phenoxypropyl)-1-azoniabicyclo[2. 2. 2]octane-d5 Bromide; Aclidinium-d5 Bromide; Genuair-d5; LAS 34273-d5; LAS-W 330-d5. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C26H25D5BrNO4S2, Molecular Weight: 569.59. US Biological Life Sciences.
Worldwide
Aclidinomycin A
Aclidinomycin A is a nalidixin antibiotic isolated from the Streptomyces halstedi. Aclidinomycin has anti-gram-positive bacteria and tumor activity. Molecular formula: C21H25N3O6. Mole weight: 415.44.
Aclidinomycin B
Aclidinomycin B is a nalidixin antibiotic isolated from the Streptomyces halstedi. Aclidinomycin has anti-gram-positive bacteria and tumor activity. Molecular formula: C21H25N3O7. Mole weight: 431.44.
Ac-Linaclotide
Ac-Linaclotide is an impurity of Linaclotide, which is a peptide agonist of guanylate cyclase 2C used for the treatment of abdominal pain in patients with irritable bowel syndrome (IBS) associated with constipation. Synonyms: Ac-L-cysteinyl-L-cysteinyl-L-alpha-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-aspargenyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonyl-glycyl-L-cysteinyl-L-tyrosine (1-6),(2-10),(5-13)-tris(disulfide); Ac-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr-OH (disulfide bridges between 1-6, 2-10 and 5-13 Cysteines); N-Acetyl-linaclotide; L-Tyrosine, N-acetyl-L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyclic (1?6),(2?10),(5?13)-tris(disulfide). CAS No. 1422389-17-0. Molecular formula: C61H81N15O22S6. Mole weight: 1568.76.
Aclonifen
Aclonifen. Group: Biochemicals. Alternative Names: 2-Chloro-6-nitro-3-phenoxyaniline; 2-Chloro-6-nitro-3-phenoxybenzenamine; Bandren; Bandur; CME 127; KUB 3359. Grades: Highly Purified. CAS No. 74070-46-5. Pack Sizes: 1g. Molecular Formula: C12H9ClN2O3, Molecular Weight: 264.66. US Biological Life Sciences.
Worldwide
Aclonifen-d5
Aclonifen-d5. Group: Biochemicals. Alternative Names: 2-Chloro-6-nitro-3-phenoxybenzenamine; 2-Chloro-6-nitro-3-phenoxyaniline; Bandren; Bandur; CME 127; KUB 3359. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C12H4D5ClN2O3, Molecular Weight: 269.7. US Biological Life Sciences.