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The enzyme is involved in the synthesis of the aklavinone aglycone, a common precursor for several anthracycline antibiotics including aclacinomycins, daunorubicin and doxorubicin. The enzyme from the Gram-negative bacterium Streptomyces sp. C5 produces daunomycin. Group: Enzymes. Synonyms: dauE (gene name); aknU (gene name). Enzyme Commission Number: EC 1.1.1.362. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0279; aklaviketone reductase; EC 1.1.1.362; dauE (gene name); aknU (gene name). Cat No: EXWM-0279.
Aklavin
It is produced by the strain of Streptomyces galilaeus. It has the activity of resisting gram positive bacterium, negative bacterium, candida and ringworm. Synonyms: Aclacinomycin T; 1-Deoxypyrromycin; Aclacinomycin; Doxypyrromycin; NSC 100290; CHEBI:74351; 1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-4-((2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexapyranosyl)oxy)-, methyl ester, (1R-(1-alpha,2-beta,4-beta))-; aklavine. CAS No. 60504-57-6. Molecular formula: C30H35NO10. Mole weight: 569.60.
Aklavinone
Aklavinone is an anthracycline drug with an antitumor effect. CAS No. 16234-96-1. Molecular formula: C22H20O8. Mole weight: 412.39.
aklavinone 12-hydroxylase
The enzymes from the Gram-positive bacteria Streptomyces peucetius and Streptomyces purpurascens participate in the biosynthesis of daunorubicin, doxorubicin and rhodomycins. The enzyme from Streptomyces purpurascens is an FAD monooxygenase. Group: Enzymes. Synonyms: DnrF; RdmE; aklavinone 11-hydroxylase (incorrect). Enzyme Commission Number: EC 1.14.13.180. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0779; aklavinone 12-hydroxylase; EC 1.14.13.180; DnrF; RdmE; aklavinone 11-hydroxylase (incorrect). Cat No: EXWM-0779.
aklavinone 7-L-rhodosaminyltransferase
Isolated from the bacterium Streptomyces galilaeus. Forms a complex with its accessory protein AknT, and has very low activity in its absence. The enzyme can also use dTDP-2-deoxy-β-L-fucose. Involved in the biosynthesis of other aclacinomycins. Group: Enzymes. Synonyms: AknS/AknT; aklavinone 7-β-L-rhodosaminyltransferase; dTDP-β-L-rhodosamine:aklavinone 7-α-L-rhodosaminyltransferase. Enzyme Commission Number: EC 2.4.1.326. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2563; aklavinone 7-L-rhodosaminyltransferase; EC 2.4.1.326; AknS/AknT; aklavinone 7-β-L-rhodosaminyltransferase; dTDP-β-L-rhodosamine:aklavinone 7-α-L-rhodosaminyltransferase. Cat No: EXWM-2563.
Aklomide
Aklomide is antiprotozoal agent against coccidiosis. Synonyms: 2-chloro-4-nitrobenzamide 2-Chloro-4-nitrobenzamide aklomide 3011-89-0 Aklomix Clomide Alkomide Benzamide, 2-chloro-4-nitro- component of Aklomix component of Novastat-W. CAS No. 3011-89-0. Molecular formula: C7H5ClN2O3. Mole weight: 200.58.
AKN-028
AKN-028, the FLT3/KIT kinase inhibitor, is an orally bioavailable protein tyrosine kinase inhibitor for FMS-related tyrosine kinase 3 (FLT3; STK1) and stem cell factor receptor (SCFR; KIT), with potential antineoplastic activity. FLT3/KIT kinase inhibitor AKN-028 binds to and inhibits both the wild-type and mutated forms of FLT3 and SCFR. This may result in an inhibition of tumor cell proliferation in cancer cell types that overexpress these receptor tyrosine kinases. Synonyms: AKN 028; AKN028; N2-(1H-Indol-5-yl)-6-(pyridin-4-yl)pyrazine-2,3-diamine; 2,3-Pyrazinediamine, N3-1H-indol-5-yl-5-(4-pyridinyl)-; N3-(1H-Indol-5-yl)-5-(4-pyridinyl)-2,3-pyrazinediamine. Grades: ≥95%. CAS No. 1175017-90-9. Molecular formula: C17H14N6. Mole weight: 302.33.
AKOS 90779
AKOS 90779. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS 90779;4,5-DICHLORO-2-PYRIDIN-2-YL-2H-PYRIDAZIN-3-ONE;AKOS BBV-017632;UKRORGSYN-BB BBV-017632. Product Category: Heterocyclic Organic Compound. CAS No. 78389-19-2. Molecular formula: C9H5Cl2N3O. Mole weight: 242.064. Purity: 0.96. IUPACName: 4,5-dichloro-2-pyridin-2-ylpyridazin-3-one. Canonical SMILES: C1=CC=NC(=C1)N2C(=O)C(=C(C=N2)Cl)Cl. Density: 1.546g/cm³. Product ID: ACM78389192. Alfa Chemistry ISO 9001:2015 Certified.
Akos akm00654
Akos akm00654. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MolPort-001-797-479, NSC164165, AKM00654, CID295009, STK413020, ZINC00112699, 1-(4-chlorophenyl)-3-naphthalen-1-ylurea, 13257-14-2. Product Category: Heterocyclic Organic Compound. CAS No. 13257-14-2. Molecular formula: C17H13ClN2O. Mole weight: 296.751. Purity: 0.96. IUPACName: 1-(4-chlorophenyl)-3-naphthalen-1-ylurea. Canonical SMILES: C1=CC=C2C(=C1)C=CC=C2NC(=O)NC3=CC=C(C=C3)Cl. Density: 1.374g/cm³. Product ID: ACM13257142. Alfa Chemistry ISO 9001:2015 Certified.
Akos b004665
Akos b004665. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS B004665;CHEMBRDG-BB 7381871;2-CHLORO-4-FORMYL-6-METHOXYPHENYL ACETATE;ACETIC ACID2-CHLORO-4-FORMYL-6-METHOXY-PHENYL ESTER;ART-CHEM-BB B004665;VITAS-BB TBB008051. Product Category: Heterocyclic Organic Compound. CAS No. 63055-10-7. Molecular formula: C10H9ClO4. Product ID: ACM63055107. Alfa Chemistry ISO 9001:2015 Certified.
Akos b004827
Akos b004827. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS B004827;ASISCHEM R44478;CHEMBRDG-BB 6439485;(2-BROMO-4-FORMYL-6-METHOXYPHENOXY)ACETIC ACID;ART-CHEM-BB B004827;VITAS-BB TBB001423. Product Category: Heterocyclic Organic Compound. CAS No. 677012-43-0. Molecular formula: C10H9BrO5. Mole weight: 289.08. Product ID: ACM677012430. Alfa Chemistry ISO 9001:2015 Certified.
Akos b013860
Akos b013860. Uses: Designed for use in research and industrial production. Additional or Alternative Names: TIMTEC-BB SBB009318;AKOS B013860;CHEMBRDG-BB 3013860;ART-CHEM-BB B013860;2-(2-Isopropylphenoxy)propanoic acid. Product Category: Heterocyclic Organic Compound. CAS No. 161790-37-0. Molecular formula: C12H16O3. Mole weight: 208.25. Product ID: ACM161790370. Alfa Chemistry ISO 9001:2015 Certified.
Akos b013910
Akos b013910. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CHEMBRDG-BB 3013910;ART-CHEM-BB B013910;AKOS B013910;2-(2-Chloro-5-methylphenoxy)-2-methylpropanoic acid. Product Category: Heterocyclic Organic Compound. CAS No. 588692-86-8. Molecular formula: C11H13ClO3. Mole weight: 228.67. Product ID: ACM588692868. Alfa Chemistry ISO 9001:2015 Certified.
Akos b015243
Akos b015243. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CHEMBRDG-BB 3015243;ART-CHEM-BB B015243;AKOS B015243;2-(4-Methyl-2-nitrophenoxy)propanohydrazide. Product Category: Heterocyclic Organic Compound. CAS No. 588678-31-3. Molecular formula: C10H13N3O4. Mole weight: 239.23. Product ID: ACM588678313. Alfa Chemistry ISO 9001:2015 Certified.
Akos b017986
Akos b017986. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BUTTPARK 83\07-41;CHEMBRDG-BB 3017986;ART-CHEM-BB B017986;AKOS B017986;5-(5-Chloro-2-methoxyphenyl)-4-methyl-4H-1,2,4-triazole-3-thiol;Albb-003285. Product Category: Heterocyclic Organic Compound. CAS No. 370855-34-8. Molecular formula: C10H10ClN3OS. Mole weight: 255.72. Product ID: ACM370855348. Alfa Chemistry ISO 9001:2015 Certified.
AKOS B018304
AKOS B018304 is a potent inhibitor of chikungunya virus with low micromolar activity. Synonyms: (E)-2-Mercapto-5-(2-Nitrobenzylidene)Thiazol-4(5H)-One; O-Nitrobenzalrhodanin. Grades: 98%. CAS No. 6308-22-1. Molecular formula: C10H6N2O3S2. Mole weight: 266.3.
Akos b023208
Akos b023208. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS B023208;ART-CHEM-BB B023208;CHEMBRDG-BB 5524838;2-(4-METHOXYPHENYL)-N-(1-NAPHTHYLMETHYL)ETHANAMINE. Product Category: Heterocyclic Organic Compound. CAS No. 416889-35-5. Molecular formula: C20H21NO. Mole weight: 291.39. Product ID: ACM416889355. Alfa Chemistry ISO 9001:2015 Certified.
Akos b023217
Akos b023217. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ART-CHEM-BB B023217;CHEMBRDG-BB 5572794;AKOS B023217;TIMTEC-BB SBB009636;(1,3-BENZODIOXOL-5-YLMETHYL)ISOPROPYLAMINE;BENZO[1,3]DIOXOL-5-YLMETHYL-ISOPROPYL-AMINE;UKRORGSYN-BB BBV-164851. Product Category: Heterocyclic Organic Compound. CAS No. 68291-92-9. Molecular formula: C11H15NO2. Mole weight: 193.24. Product ID: ACM68291929. Alfa Chemistry ISO 9001:2015 Certified.
Akos b023249
Akos b023249. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS B023249;ART-CHEM-BB B023249;CHEMBRDG-BB 5535937;TIMTEC-BB SBB009642;(2,4-DIMETHOXYBENZYL)[2-(4-FLUOROPHENYL)ETHYL]AMINE. Product Category: Heterocyclic Organic Compound. CAS No. 355382-64-8. Molecular formula: C17H20FNO2. Mole weight: 289.34. Product ID: ACM355382648. Alfa Chemistry ISO 9001:2015 Certified. Categories: N-(2,4-Dimethoxybenzyl)-2-(4-fluorophenyl)ethanamine hydrochloride.
Akos b023256
Akos b023256. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CHEMBRDG-BB 5549545;ART-CHEM-BB B023256;AKOS B023256;TIMTEC-BB SBB009643;(4-BROMOBENZYL)[2-(3,4-DIMETHOXYPHENYL)ETHYL]AMINE. Product Category: Heterocyclic Organic Compound. CAS No. 133344-77-1. Molecular formula: C17H20BrNO2. Mole weight: 350.25. Product ID: ACM133344771. Alfa Chemistry ISO 9001:2015 Certified.
AKOS B028903
AKOS B028903 (CAS# 692275-23-3 ) is a useful research chemical. Synonyms: AKOS B028903; CHEMBRDG-BB 7420349; 2-CHLORO-5-ETHOXY-4-PROPOXY-BENZALDEHYDE; ART-CHEM-BB B028903; VITAS-BB TBB009798. Grades: 95 %. CAS No. 692275-23-3. Molecular formula: C12H15ClO3. Mole weight: 242.70.
Akos b028906
Akos b028906. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS B028906;CHEMBRDG-BB 7389354;2-CHLORO-5-ETHOXY-4-ISOPROPOXY-BENZALDEHYDE;ART-CHEM-BB B028906;VITAS-BB TBB009799. Product Category: Heterocyclic Organic Compound. CAS No. 692267-55-3. Molecular formula: C12H15ClO3. Mole weight: 242.701. Product ID: ACM692267553. Alfa Chemistry ISO 9001:2015 Certified. Categories: 2-CHLORO-5-ETHOXY-4-ISOPROPOXYBENZALDEHYDE.
AKOS B028906
AKOS B028906 (CAS# 692267-55-3 ) is a useful research chemical. Synonyms: AKOS B028906; CHEMBRDG-BB 7389354; 2-CHLORO-5-ETHOXY-4-ISOPROPOXY-BENZALDEHYDE; ART-CHEM-BB B028906; VITAS-BB TBB009799. Grades: 95 %. CAS No. 692267-55-3. Molecular formula: C12H15ClO3. Mole weight: 242.70.
Akos b029140
Akos b029140. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CHEMBRDG-BB 7745536;AKOS B029140;3-(5-OXO-3-PROPYL-4,5-DIHYDRO-1H-PYRAZOL-1-YL)BENZOIC ACID;3-(5-OXO-3-PROPYL-4,5-DIHYDRO-PYRAZOL-1-YL)-BENZOIC ACID;ART-CHEM-BB B029140;VITAS-BB TBB009862. Product Category: Heterocyclic Organic Compound. CAS No. 701221-57-0. Molecular formula: C13H14N2O3. Product ID: ACM701221570. Alfa Chemistry ISO 9001:2015 Certified.
AKOS B029152
AKOS B029152 (CAS# 700849-61-2 ) is a useful research chemical. Synonyms: AKOS B029152; CHEMBRDG-BB 7726699; 4-(5-OXO-3-PROPYL-2,5-DIHYDRO-1H-PYRAZOL-1-YL)BENZOIC ACID; 4-(5-OXO-3-PROPYL-2,5-DIHYDRO-PYRAZOL-1-YL)-BENZOIC ACID; ART-CHEM-BB B029152; VITAS-BB TBB009868. Grades: 95 %. CAS No. 700849-61-2. Molecular formula: C13H14N2O3. Mole weight: 246.26.
Akos b029363
Akos b029363. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS B029363;CHEMBRDG-BB 7454605;5-CHLORO-2-ISOPROPOXY-3-METHOXY-BENZALDEHYDE;ART-CHEM-BB B029363. Product Category: Heterocyclic Organic Compound. CAS No. 827593-20-4. Molecular formula: C11H13ClO3. Mole weight: 228.674. Product ID: ACM827593204. Alfa Chemistry ISO 9001:2015 Certified. Categories: 5-CHLORO-2-ISOPROPOXY-3-METHOXYBENZALDEHYDE.
AKOS B029817
AKOS B029817 (CAS# 590376-72-0 ) is a useful research chemical. Synonyms: AKOS B029817; CHEMBRDG-BB 7763392; 2-(4-CHLORO-2-FORMYLPHENOXY)ACETAMIDE; ART-CHEM-BB B029817; VITAS-BB TBB002769. Grades: 95 %. CAS No. 590376-72-0. Molecular formula: C9H8ClNO3. Mole weight: 213.62.
Akos b033181
Akos b033181. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS B033181;AKOS BC-0108;TIMTEC-BB SBB011152;2-(2-(PYRROLIDIN-1-YL)ETHOXY)ANILINE;2-(2-PYRROLIDIN-1-YL-ETHOXY)-PHENYLAMINE;ART-CHEM-BB B033181;ART-CHEM-BB B037560;VITAS-BB TBB001496. Product Category: Heterocyclic Organic Compound. CAS No. 878733-59-6. Molecular formula: C12H18N2O. Mole weight: 206.284120 [g/mol]. Purity: 0.96. IUPACName: 2-(2-pyrrolidin-1-ylethoxy)aniline. Canonical SMILES: C1CCN(C1)CCOC2=CC=CC=C2N. Product ID: ACM878733596. Alfa Chemistry ISO 9001:2015 Certified.
Akos bb-2983
Akos bb-2983. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS BB-2983;CHEMBRDG-BB 6698389;[4-(3-FORMYL-2,5-DIMETHYL-1H-PYRROL-1-YL)PHENOXY]ACETIC ACID. Product Category: Heterocyclic Organic Compound. CAS No. 662154-28-1. Molecular formula: C15H15NO4. Mole weight: 273.28. Product ID: ACM662154281. Alfa Chemistry ISO 9001:2015 Certified.
Akos bb-3561
Akos bb-3561. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CHEMBRDG-BB 6491933;AKOS BB-3561;1-[4-(DIMETHYLAMINO)PHENYL]-2,5-DIMETHYL-1H-PYRROLE-3-CARBALDEHYDE. Product Category: Heterocyclic Organic Compound. CAS No. 32570-93-7. Molecular formula: C15H18N2O. Mole weight: 242.32. Product ID: ACM32570937. Alfa Chemistry ISO 9001:2015 Certified.
Akos bb-3568
Akos bb-3568. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CHEMBRDG-BB 9003047;AKOS BB-3568;4-(3-ACETYL-2,5-DIMETHYL-1H-PYRROL-1-YL)BENZOIC ACID. Product Category: Heterocyclic Organic Compound. CAS No. 870540-39-9. Molecular formula: C15H15NO3. Product ID: ACM870540399. Alfa Chemistry ISO 9001:2015 Certified.
Akos bb-9394
Akos bb-9394. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS BB-9394;TIMTEC-BB SBB011112;2-((PYRROLIDIN-1-YL)METHYL)BENZOIC ACID;OTAVA-BB 7020661509. Product Category: Heterocyclic Organic Compound. CAS No. 876717-98-5. Molecular formula: C12H15NO2. Mole weight: 205.253000 [g/mol]. Purity: 0.96. IUPACName: 2-(pyrrolidin-1-ylmethyl)benzoic acid. Canonical SMILES: C1CCN(C1)CC2=CC=CC=C2C(=O)O. Product ID: ACM876717985. Alfa Chemistry ISO 9001:2015 Certified.
Akos bb-9805
Akos bb-9805. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-ethyl-2-pyrrolidin-1-ylethanamine, N-ethyl-2-(1-pyrrolidinyl)ethanamine, ST088030, 138356-55-5, ethyl(2-pyrrolidinylethyl)amine, AGN-PC-003SQO, SureCN5430626, CTK4C1222, MolPort-004-947-147, 1-Pyrrolidineethanamine, N-ethyl-, SBB007481, AKOS004120645, ethyl[2-(pyrrolidin-1-yl)ethyl]amine, AG-D-77613, MCULE-2763787370, KB-58188, KB-258727, FT-0683213, I05-1155. Product Category: Heterocyclic Organic Compound. CAS No. 138356-55-5. Molecular formula: C8H18N2. Mole weight: 142.241920 [g/mol]. Purity: 0.96. IUPACName: N-ethyl-2-pyrrolidin-1-ylethanamine. Canonical SMILES: CCNCCN1CCCC1. Density: 0.894g/cm³. Product ID: ACM138356555. Alfa Chemistry ISO 9001:2015 Certified.
AKOS BBS-00000303
AKOS BBS-00000303. Uses: Designed for use in research and industrial production. Additional or Alternative Names: IFLAB-BB F1420-0302;AKOS BBS-00000303;2-AMINO-BENZOTHIAZOLE-6-SULFONIC ACID METHYLAMIDE. Product Category: Heterocyclic Organic Compound. CAS No. 18101-53-6. Molecular formula: C8H9N3O2S2. Mole weight: 243.31. Product ID: ACM18101536. Alfa Chemistry ISO 9001:2015 Certified.
AKOS BBS-00000304
AKOS BBS-00000304. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS BBS-00000304;IFLAB-BB F1420-0612;2-AMINO-BENZOTHIAZOLE-6-SULFONIC ACID DIMETHYLAMIDE. Product Category: Heterocyclic Organic Compound. CAS No. 17901-13-2. Molecular formula: C9H11N3O2S2. Mole weight: 257.33. Product ID: ACM17901132. Alfa Chemistry ISO 9001:2015 Certified.
AKOS BBS-00000987
AKOS BBS-00000987. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS BBS-00000987;IFLAB-BB F1990-0009;4-((3,5-DIMETHYL-1H-PYRAZOL-4-YL)SULFONYL)MORPHOLINE. Product Category: Heterocyclic Organic Compound. CAS No. 80466-86-0. Molecular formula: C9H15N3O3S. Mole weight: 245.3. Product ID: ACM80466860. Alfa Chemistry ISO 9001:2015 Certified. Categories: 4-[(3,5-dimethyl-1H-pyrazol-4-yl)sulfonyl]morpholine.
Akos bbs-00000988
Akos bbs-00000988. Uses: Designed for use in research and industrial production. Additional or Alternative Names: IFLAB-BB F0918-6658;AKOS BBS-00000988;1-(3,5-DIMETHYL-1H-PYRAZOLE-4-SULFONYL)-PIPERIDINE. Product Category: Heterocyclic Organic Compound. CAS No. 91141-46-7. Molecular formula: C10H17N3O2S. Mole weight: 243.33. Product ID: ACM91141467. Alfa Chemistry ISO 9001:2015 Certified.
Akos bbs-00001550
Akos bbs-00001550. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ethyl 7-methoxy-2-methylquinoline-3-carboxylate, SBB039122, 86210-91-5, 7-Methoxy-2-methylquinoline-3-carboxylic acid ethyl ester, ZINC08253055, AC1NHA95, SureCN1574317, MolPort-000-499-443, STL227739, AKOS000267314, AB23714, MCULE-5971957867, KB-250011, ST45174704, T5559039, 7-METHOXY-2-METHYL-3-QUINOLINECARBOXYLIC ACID ETHYL ESTER. Product Category: Heterocyclic Organic Compound. CAS No. 86210-91-5. Molecular formula: C14H15NO3. Mole weight: 245.27. Purity: 0.96. IUPACName: ethyl 7-methoxy-2-methylquinoline-3-carboxylate. Canonical SMILES: CCOC(=O)C1=C(N=C2C=C(C=CC2=C1)OC)C. Density: 1.159g/cm³. Product ID: ACM86210915. Alfa Chemistry ISO 9001:2015 Certified.
Akos bbs-00001917
Akos bbs-00001917. Uses: Designed for use in research and industrial production. Additional or Alternative Names: IFLAB-BB F2124-0038;CHEMBRDG-BB 9025926;AKOS BBS-00001917;(5-ETHYL-1-BENZOFURAN-3-YL)ACETIC ACID;AKOS A0602-0443;OTAVA-BB 7118560541. Product Category: Heterocyclic Organic Compound. CAS No. 882248-24-0. Molecular formula: C12H12O3. Mole weight: 204.22. Product ID: ACM882248240. Alfa Chemistry ISO 9001:2015 Certified.
Akos bbs-00005383
Akos bbs-00005383. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS BBS-00005383;ASISCHEM C33117;1H-[1,2]DITHIOLO[3,4-C]QUINOLINE-1-THIONE, 5-(CHLOROACETYL)-4,5-DIHYDRO-4,4,7,8-TETRAMETHYL-;5-(CHLOROACETYL)-4,5-DIHYDRO-4,4,7,8-TETRAMETHYL-1H-[1,2]DITHIOLO[3,4-C]QUINOLINE-1-THIONE. Product Category: Heterocyclic Organic Compound. CAS No. 352016-99-0. Molecular formula: C16H16ClNOS3. Mole weight: 369.95. Product ID: ACM352016990. Alfa Chemistry ISO 9001:2015 Certified.
Akos bbs-00005387
Akos bbs-00005387. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ASISCHEM U52582;CHEMBRDG-BB 5101452;AKOS BBS-00005387;6-CHLORO-N,N'-DIPHENYL-1,3,5-TRIAZINE-2,4-DIAMINE;[4-(anilino)-6-chloro-s-triazin-2-yl]-phenyl-amine;6-chloro-2-N,4-N-di(phenyl)-1,3,5-triazine-2,4-diamine;6-chloro-N2,N4-di(phenyl)-1,3,5-triazine-2,4. Product Category: Heterocyclic Organic Compound. CAS No. 1973-9-7. Molecular formula: C15H12ClN5. Mole weight: 297.74. Product ID: ACM1973097. Alfa Chemistry ISO 9001:2015 Certified. Categories: NSC 76482.
Akos bbs-00005437
Akos bbs-00005437. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ASISCHEM C34560;AKOS BBS-00005437;1H-[1,2]DITHIOLO[3,4-C]QUINOLINE-1-THIONE, 5-(2-CHLORO-1-OXOPROPYL)-4,5-DIHYDRO-4,4,8-TRIMETHYL-;5-(2-CHLORO-1-OXOPROPYL)-4,5-DIHYDRO-4,4,8-TRIMETHYL-1H-[1,2]DITHIOLO[3,4-C]QUINOLINE-1-THIONE. Product Category: Heterocyclic Organic Compound. CAS No. 375360-52-4. Molecular formula: C16H16ClNOS3. Mole weight: 369.95. Product ID: ACM375360524. Alfa Chemistry ISO 9001:2015 Certified.
Akos bbs-00005522
Akos bbs-00005522. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS BBS-00005522;ASISCHEM C37647;2-QUINAZOLINAMINE, 4-METHYL-N-[1,4,5,6-TETRAHYDRO-5-(2-PHENYLETHYL)-1,3,5-TRIAZIN-2-YL]-;4-METHYL-N-[1,4,5,6-TETRAHYDRO-5-(2-PHENYLETHYL)-1,3,5-TRIAZIN-2-YL]-2-QUINAZOLINAMINE. Product Category: Heterocyclic Organic Compound. CAS No. 672338-32-8. Molecular formula: C20H22N6. Mole weight: 346.43. Product ID: ACM672338328. Alfa Chemistry ISO 9001:2015 Certified.
Akos bbs-00006061
Akos bbs-00006061. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CHEMBRDG-BB 7113032;AKOS BBS-00006061;3-(4-BROMOPHENYL)-7-HYDROXY-2-METHYL-4H-CHROMEN-4-ONE. Product Category: Heterocyclic Organic Compound. CAS No. 610758-58-2. Molecular formula: C16H11BrO3. Mole weight: 331.16. Product ID: ACM610758582. Alfa Chemistry ISO 9001:2015 Certified.
Akos bbs-00008052
Akos bbs-00008052. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS BBS-00008052;CHEMBRDG-BB 5363606;(2E)-3-(2-CHLOROPHENYL)-N-(3-HYDROXYPHENYL)ACRYLAMIDE;AKOS A1230-3081. Product Category: Heterocyclic Organic Compound. CAS No. 300825-48-3. Molecular formula: C15H12ClNO2. Mole weight: 273.71. Product ID: ACM300825483. Alfa Chemistry ISO 9001:2015 Certified. Categories: (2E)-3-(2-chlorophenyl)-N-(3-hydroxyphenyl)prop-2-enamide.
Akos bbs-00008199
Akos bbs-00008199. Uses: Designed for use in research and industrial production. Additional or Alternative Names: OTAVA-BB BB7015500288;AKOS BBS-00008199;AKOS A1230-7211;OTAVA-BB 7015500288. Product Category: Heterocyclic Organic Compound. CAS No. 91153-72-9. Molecular formula: C14H15NO4. Mole weight: 261.27. Product ID: ACM91153729. Alfa Chemistry ISO 9001:2015 Certified.
Akos bc-1738
Akos bc-1738. Uses: Designed for use in research and industrial production. Additional or Alternative Names: TOSLAB 97274;AKOS BC-1738;CHEMBRDG-BB 6034708;2-[2-(4-BROMOPHENYL)-2-OXOETHOXY]BENZAMIDE. Product Category: Heterocyclic Organic Compound. CAS No. 337925-74-3. Molecular formula: C15H12BrNO3. Mole weight: 334.16. Product ID: ACM337925743. Alfa Chemistry ISO 9001:2015 Certified.
Akos bc-1945
Akos bc-1945. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS BC-1945;CHEMBRDG-BB 9071388;3-(3,4-DIMETHYLPHENOXY)-N-METHYL-1-PROPANAMINE;UKRORGSYN-BB BBV-182444. Product Category: Heterocyclic Organic Compound. CAS No. 915923-36-3. Molecular formula: C12H19NO. Mole weight: 193.288. Product ID: ACM915923363. Alfa Chemistry ISO 9001:2015 Certified.
Akos bc-1949
Akos bc-1949. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS BC-1949;CHEMBRDG-BB 9070580;N-METHYL-3-(4-METHYLPHENOXY)-1-PROPANAMINE;UKRORGSYN-BB BBV-253231. Product Category: Heterocyclic Organic Compound. CAS No. 915923-08-9. Molecular formula: C11H17NO. Mole weight: 179.261. Product ID: ACM915923089. Alfa Chemistry ISO 9001:2015 Certified.
Akos bc-3058
Akos bc-3058. Uses: Designed for use in research and industrial production. Additional or Alternative Names: IFLAB-BB F0898-0214;AKOS BC-3058;N-[1-AMINO-1-PHENYL-METH-(Z)-YLIDENE]-BENZENESULFONAMIDE. Product Category: Heterocyclic Organic Compound. CAS No. 14067-77-7. Molecular formula: C13H12N2O2S. Mole weight: 260.31. Product ID: ACM14067777. Alfa Chemistry ISO 9001:2015 Certified.
Akos pao-0857
Akos pao-0857. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS PAO-0857;CHEMBRDG-BB 4002917;3-(1-METHYL-1H-PYRAZOL-4-YL)PROPAN-1-OL. Product Category: Heterocyclic Organic Compound. CAS No. 192661-38-4. Molecular formula: C7H12N2O. Mole weight: 140.18. Product ID: ACM192661384. Alfa Chemistry ISO 9001:2015 Certified.
Akos pao-1153
Akos pao-1153. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS PAO-1153;3-Isobutyl-1H-pyrazole. Product Category: Heterocyclic Organic Compound. CAS No. 98816-40-1. Molecular formula: C7H12N2. Product ID: ACM98816401. Alfa Chemistry ISO 9001:2015 Certified.
AKR1C1 Inhibitor, 5-PBSA
A cell-permeable salicylic acid compound that acts as a highly potent, active-site directed and substrate competitive AKR1C1 inhibitor (Ki=4nM) with moderate to excellent selectivity over AKR1C2, AKR1C3 and AKR1C4 (Ki=0.087, 4.2 and 18.2uM, respectively). Shown to inhibit the metabolism of progesterone by AKR1C1 (IC50=460nM in AKR1C1 overexpressing BAECs).CAS No.4906-68-7. Group: Biochemicals. Alternative Names: Aldo-Keto Reductase family 1 member C1 Inhibitor, 5-PBSA, 3-Bromo-5-phenylsalicylic acid, 20α-Hydroxysteroid Dehydrogenase Inhibitor, 5-PBSA. Grades: Highly Purified. CAS No. 4906-68-7. Pack Sizes: 25mg. Molecular Formula: C??H?BrO?. US Biological Life Sciences.
A cell-permeable 3-phenyl-aminobenzoate compound that acts as a potent, competitive, reversible, active-site targeting inhibitor of aldo-keto reductase 1C3 (AKR1C3; type 5 17b-hydroxysteroid dehydrogenase) (IC50 = 60nM) with excellent selectivity over other closely related human AKR isoforms (IC50 = 22.7, 15.4, 62.7, >50, and >50uM for and AKR1C1, AKR1C2, AKR1C4, AKR1B1 and AKR1B10, respectively. Exhibits a weak inhibitory effect on cyclooxygenase 1 and 2 (IC50 = 100uM). Shown to efficiently block the AKR1C3-mediated production of testosterone in LNCaP-AKR1C3 cells (~10uM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Akrobomycin
It is produced by the strain of Actinomadura reseoviolacea 129-AVI. It has anti-gram-negative bacteria, ringworm and tumor activity. Synonyms: 9,10-Anhydro-13-deoxocarminomycin; 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-8-ethyl-9,10-dihydro-1,6,11-trihydroxy-, (S)-; DTXSID601008673; LS-94000; 3-Ethyl-5,10,12-trihydroxy-6,11-dioxo-1,2,6,11-tetrahydrotetracen-1-yl 3-amino-2,3,6-trideoxyhexopyranoside; Akrobomycin; Rubomycin Q1. CAS No. 89156-94-5. Molecular formula: C26H27NO8. Mole weight: 481.49.
Akt1 and Akt2-IN-1
Akt1 and Akt2-IN-1 is an allosteric inhibitor of Akt1 and Akt2 with the IC50 of 3.5 nM and 42 nM respectively. It has potent and balanced activity. It is dependent on the PH-domain for Akt inhibition. It is selective for Akt1/2 over Akt3 and is highly selective over other members of the AGC family of kinases in vitro. It has potent inhibitory activity against Akt1 and Akt 2 in vivo in a mouse lung and efficacy in a tumor xenograft model. It has moderate activity in an hERG binding assay and is a substrate for human P-glycoprotein. It also shows good physical properties with a human plasma protein binding. Uses: Akt1 and akt2-in-1 has potent inhibitory activity against akt1 and akt 2 and efficacy in a tumor xenograft model. Synonyms: Akt Inhibitor 17; Akti_2008; Akti 2008; Akti2008; Akti-2008; Akt Inhibitor 17; Akt-Inhibitor-17; AktInhibitor17; 3-Phenyl-2-[4-[[4-[5-(2-pyridinyl)-1H-1,2,4-triazol-3-yl]-1-piperidinyl]methyl]phenyl]-1,6-Naphthyridin-5(6H)-one;Akti_2008;3-phenyl-2-[4-[[4-(3-pyridin-2-yl-1H-1,2,4-triazol-5-yl)piperidin-1-yl]methyl]phenyl]-6H-1,6-naphthyridin-5-one. Grades: >98%. CAS No. 893422-47-4. Molecular formula: C33H29N7O. Mole weight: 539.63.
Akt Activator II, SC79 (Ethyl-2-amino-6-chloro-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate)
A cell-permeable and blood-brain barrier permeant HA14-1 analog that interacts with Akt PH domain PtdIns(3,4,5)P3- (PIP3) binding pocket, rendering Akt in a conformation susceptible to phosphorylation by upstream kinases. Shown to enhance both basal and receptor-mediated Akt phosphorylation (Thr308 and Ser473; 2 to 4ug/ml) with concomitant inhibition Akt membrane translocation in various cell cultures. Efficiently reduces glutamate-induced neurotoxicity both in primary neuron cultures (EC50 = 4ug/ml) in vitro and in a murine MCAO model (40mg/kg, i.p.) in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 305834-79-1. Pack Sizes: 25mg. Molecular Formula: C??H??ClN?O?. US Biological Life Sciences.
Worldwide
Akt Control Cell Extracts (Rac PKa, PKBa)
Akt Control Cell Extracts (Rac PKa, PKBa). Group: Biologicals. Grades: Lysate. Pack Sizes: 10Blots. US Biological Life Sciences.
Worldwide
Akt, dephosphorylated Positive Control (Ser473) (Rac PKa, PKBa)
Positive control for A1124-02D. Group: Molecular Biology. Pack Sizes: 200ul. US Biological Life Sciences.
Worldwide
Akti-1/2
Akti-1/2. Group: Biochemicals. Alternative Names: 1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]4-piperidinyl]-2H-benzimidazol-2-one. Grades: Highly Purified. CAS No. 612847-09-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C34H29N7O. US Biological Life Sciences.
Allosteric Akt (PKB) inhibitors used in synergistic combination therapy for the treatment of cancer. Group: Biochemicals. Alternative Names: 1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]guinoxalin-7-yl)phenyl]methyl]4-piperidinyl]-2H-benzimidazol-2-one. Grades: Highly Purified. CAS No. 612847-09-3. Pack Sizes: 2mg. US Biological Life Sciences.
Worldwide
Akt-I-1,2 HCl
Akt-I-1,2 is a selective, non-ATP-competitive Akt1 and Akt2 inhibitor. Synonyms: Akt I 1,2 HCl; AktI1,2 HCl; Benzenemethanamine, alpha,alpha-dimethyl-4-(3-phenyl-2-quinoxalinyl)-, hydrochloride (1:1). CAS No. 473382-50-2. Molecular formula: C23H22ClN3. Mole weight: 375.90.
AKTide-2T
AKTide-2T, a peptide substrate for Akt/PKB, has been found to act as an inhibitor and mimics the optimal phosphorylation sequence of Akt. Synonyms: AKTide-2T; 324029-01-8; ARKRERTYSFGHHA; AKOS024457090; PD079315. Grades: ≥95% by HPLC. CAS No. 324029-01-8. Molecular formula: C74H114N28O20. Mole weight: 1715.89.
AKTide-2T
AKTide-2T. Group: Biochemicals. Grades: Purified. CAS No. 324029-01-8. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
AKT-IN-23
AKT-IN-23 is an AKT inhibitor. AKT-IN-23 can be used in cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1226801-23-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-161704.
Cell-permeable. A potent and selective inhibitor of Akt1/Akt2 activity (IC?? = 58nM (Akt1), 210nM (Akt2) and 2.12uM (Akt3) in in vitro kinase assays). The inhibition appears to be pleckstrin homology (PH) domain-dependent. It does not exhibit any inhibitory effect against PH domain-lacking Akts, or other closely related AGC family kinases, PKA, PKC, and SGK, even at concentrations (50uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 612847-09-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Akt Inhibitor IV
Akt inhibitor IV is an inhibitor of Akt activation that inhibits Akt-mediated nuclear export of Forkhead box class O transcription factor 1a (FOXO1a; IC50 = 625 nM) and reduces phosphorylation of Akt at Ser473 and Thr308 in a dose-dependent manner. Synonyms: 5-(2-Benzothiazolyl)-3-ethyl-2-[2-(methylphenylamino)ethenyl]-1-phenyl-1H-benzimidazolium iodide. Grades: ≥95%. CAS No. 681281-88-9. Molecular formula: C31H27N4S·I. Mole weight: 614.6.
AKT inhibitor IV
Akt inhibitor-IV (AKTIV) acts as a PI3K-Akt inhibitor at the E isomer (HY-14971), with potent cytotoxicity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AKTIV. CAS No. 681281-88-9. Pack Sizes: 1 mg. Product ID: HY-14971A.
AKT inhibitor VIII
Akt Inhibitor VIII is a cell-permeable quinoxaline compound that has been shown to potently, selectively, allosterically, and reversibly inhibit Akt1, Akt2, and Akt3 activity. It does not exhibit any inhibitory effect against pleckstrin homology (PH) domain-lacking Akts, AGC family kinases, PKA, PKC or SGK. It also prevails over Akt1/Akt2-mediated resistance to chemotherapeutics in tumor cells and has been shown to block basal and stimulated phosphorylation/activation of Akt1/Akt2 in cultured cells and in mice. Synonyms: AKT inhibitor VIII; AKT-inhibitor-VIII; AKT inhibitor-8; AKT-inhibitor-8; Akt-I 1,2; Akti-1/2. Sigma-A6730. 2H-Benzimidazol-2-one, 1,3-dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]-4-piperidinyl]-. Grades: >98%. CAS No. 612847-09-3. Molecular formula: C34H29N7O. Mole weight: 551.64.
A cell-permeable, reversible, potent, and selective inhibitor of Akt1/Akt2 activity (IC50=58nM, 210nM, and 2.12uM for Akt1, Akt2, and Akt3, respectively, in in vitro kinase assays). The inhibition is reported to be pleckstrin homology (PH) domain-dependent. It does not exhibit any inhibitory effect against PH domain-lacking Akts, or other closely related AGC family kinases, PKA, PKC, and SGK, even at concentrations as high as 50uM. Overcomes Akt1/Akt2-mediated resistance to chemotherapeutics in tumor cells and is shown to block basal and stimulated phosphorylation / activation of Akt1/Akt2 both in cultured cells in vitro and in mice in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 612847-09-3. Pack Sizes: 1mg, 5mg. US Biological Life Sciences.