American Chemical Suppliers

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Product
AGI-6780 AGI-6780 is an IDH2 inhibitor that potently and selectively inhibits the tumor-associated mutant IDH2/R140Q with IC50 of 23±1.7 nM. AGI-6780 is less potent against IDH2WT with IC50of 190±8.1 nM. Synonyms: AGI6780; AGI 6780; AGI-6780. CAS No. 1432660-47-3. Molecular formula: C21H18F3N3O3S2. Mole weight: 481.508. BOC Sciences 2
AGI-B4 AGI-B4 is a substance produced by Aspergillus sp. Y80118 that inhibits the growth of endothelial cells. It inhibits the proliferation of human umbilical vein endothelial cells (HUVECs) induced by vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF) and endothelial cell growth factor (ECGS) with IC50 of 1.4 μmol/ L, 2.8 μmol/L and 6.2 μmol/L. Synonyms: (7R,8R)-AGI-B4. CAS No. 1313588-44-1. Molecular formula: C16H14O7. Mole weight: 318.28. BOC Sciences
Agigenin Agigenin. Group: Biochemicals. Alternative Names: (2R, 2aS, 2'R, 4R, 5R, 5'R, 6aR, 6bS, 8aS, 8bR, 9S, 11aS, 12aS, 12bR) -5', 6a, 8a, 9-Tetra methyl docosahydrospiro [naphtho [2', 1': 4, 5] indeno [2, 1-b] furan-10, 2'-pyran] -2, 4, 5-triol. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 3
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AgI Silica Core Shell Nanoparticles AgI Silica Core Shell Nanoparticles. Group: Core shell nanoparticles. 99.9%. Alfa Chemistry Materials 3
AgI Silica Core Shell Nanoparticles AgI Silica Core Shell Nanoparticles. Group: Core shell nanoparticles. CAS No. 67762-90-7. 99.9%. Alfa Chemistry Materials 3
Agistatin B ((2R,4S,4aR,5R,6R,8aR)-6-Ethyloctahydro-2H-2,5-epoxy-chromene-4,4a-diol) Tricyclic analog of agistatin A. Cholesterol biosynthesis inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 144096-46-8. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. USBiological 4
Worldwide
Agistatin D ((4aS,5R,6R)-6-Ethyl-4a,5-dihydroxy-4a,5,6,7-tetrahydro-4H-chromen-4-one) Analog of agistatin A. Cholesterol biosynthesis inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 144096-47-9. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 4
Worldwide
Agistatin E Agistatin E is a novel pyranacetal isolated from fungus FH-A 6239. It has been used as a cholesterol biosynthesis inhibitor. Mycotoxin. Synonyms: Agistatin E; 144096-48-0; (1S,3S,6R,7R,8R)-6-ethyl-3,8-dihydroxy-2,11-dioxatricyclo[5.3.1.03,8]undecan-9-one; HY-N10232; CS-0109121; J-007915. Grades: ≥98%. CAS No. 144096-48-0. Molecular formula: C11H16O5. Mole weight: 228.24. BOC Sciences
Agistatin E ((2S,4aR,5S,8R,8aR)-8-Ethyl-4a,5-dihydroxy-hexahydro-2H-2,5-epoxychromen-4(3H)-one) Tricyclic analog of agistatin A. Cholesterol biosynthesis inhibitor. Mycotoxin. Group: Biochemicals. Grades: Highly Purified. CAS No. 144096-48-0. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. USBiological 4
Worldwide
Agitoxin 2 Agitoxin 2. Group: Biochemicals. Grades: Purified. CAS No. 168147-41-9. Pack Sizes: 10ug. US Biological Life Sciences. USBiological 5
Worldwide
Agitoxin 2 Agitoxin-2 is a potent and selective blocker of the Shaker type voltage-gated Kv1.3 and Kv1.1 channels. Agitoxin-2 inhibits Kv1.3 with an IC50 value of around 200 pM and Kv1.1 with an IC50 value of around 140 pM. Synonyms: AGTX2; H-Gly-Val-Pro-Ile-Asn-Val-Ser-Cys(1)-Thr-Gly-Ser-Pro-Gln-Cys(2)-Ile-Lys-Pro-Cys(3)-Lys-Asp-Ala-Gly-Met-Arg-Phe-Gly-Lys-Cys(1)-Met-Asn-Arg-Lys-Cys(2)-His-Cys(3)-Thr-Pro-Lys-OH; glycyl-L-valyl-L-prolyl-L-isoleucyl-L-asparagyl-L-valyl-L-seryl-L-cysteinyl-L-threonyl-glycyl-L-seryl-L-prolyl-L-glutaminyl-L-cysteinyl-L-isoleucyl-L-lysyl-L-prolyl-L-cysteinyl-L-lysyl-L-alpha-aspartyl-L-alanyl-glycyl-L-methionyl-L-arginyl-L-phenylalanyl-glycyl-L-lysyl-L-cysteinyl-L-methionyl-L-asparagyl-L-arginyl-L-lysyl-L-cysteinyl-L-histidyl-L-cysteinyl-L-threonyl-L-prolyl-L-lysine (8->28),(14->33),(18->35)-tris(disulfide). Grades: >98%. CAS No. 168147-41-9. Molecular formula: C169H278N54O48S8. Mole weight: 4090.87. BOC Sciences
AGK2 AGK2 is a potent, and selective SIRT2 inhibitor with IC50 of 3.5 μM. Synonyms: AGK-2; AGK 2; 2-cyano-3-(5-(2,5-dichlorophenyl)furan-2-yl)-N-(quinolin-5-yl)acrylamide. Grades: >98%. CAS No. 304896-28-4. Molecular formula: C23H13Cl2N3O2. Mole weight: 434.27. BOC Sciences 2
AGK 2 AGK 2. Group: Biochemicals. Grades: Purified. CAS No. 304896-28-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
AGK7 AGK2 is a cell-permeable, selective inhibitor of SIRT2 (IC50 = 3.5 μM) that minimally affects either SIRT1 or SIRT3 at 10-fold higher levels. AGK7 is an inactive control to be used in experiments with AGK2. Synonyms: SIRT2 Inhibitor (Inactive Control); 2-cyano-3-[5-(2,5-dichlorophenyl)furan-2-yl]-N-quinolin-8-ylprop-2-enamide. Grades: ≥95%. CAS No. 304896-21-7. Molecular formula: C23H13Cl2N3O2. Mole weight: 434.3. BOC Sciences 2
AGL 2263 AGL 2263 is an inhibitor of the insulin-like growth factor 1 receptor (IGF-1R; IC50 = 0.43 μM). Synonyms: (E)-2-(3,4-dihydroxybenzoyl)-3-(2-oxo-3H-1,3-benzoxazol-5-yl)prop-2-enenitrile. Grades: ≥98%. CAS No. 638213-98-6. Molecular formula: C17H10N2O5. Mole weight: 322.3. BOC Sciences 2
Aglafoline Aglafoline, isolated from Aglaia elliptifolia Merr, is a selective PAF-induced platelet aggregation inhibitor. And studies have shown that because aglafoline blocked the high-K+-induced contraction of rat thoracic aorta, it may also possess Ca+- channel b. Synonyms: methyl (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate Aglafoline Methyl rocaglate AGLAFOLIN CHEBI:65374 CMLDBU00002646 143901-35-3 methyl (1R,2R,3S,3aR,8bS)-1,8b-dihydr. CAS No. 143901-35-3. Molecular formula: C28H28O8. Mole weight: 492.52. BOC Sciences 2
Aglepristone Aglepristone is used as a treatment to induce parturition in ewes and their newborns. A competitive progesterone antagonist for treatment of various progesterone-dependent physiology and pathology conditions, and effective means of terminating pregnancy in most species. Also, it prevents sperm progression toward the oviducts and fertilization in inseminated females. Group: Biochemicals. Grades: Highly Purified. CAS No. 124478-60-0. Pack Sizes: 500mg, 1g. Molecular Formula: C29H37NO2, Molecular Weight: 431.61. US Biological Life Sciences. USBiological 5
Worldwide
a-Glucametacin a-Glucametacin, the acclaimed anti-inflammatory wonder, showcases its unparalleled efficacy in combating a myriad of inflammatory afflictions, notably arthritis, while effectively tackling postoperative discomfort. By impeding the production of prostaglandins and leukotrienes, this remarkable drug alleviates pain and curtails inflammation. Synonyms: 2-[[[1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl]amino]-2-deoxy-a-D-glucopyranose a-Glucametacine a-Glucamethacin. CAS No. 871014-84-5. Molecular formula: C25H27ClN2O8. Mole weight: 518.94. BOC Sciences
a-Glucan oligosaccharide a-Glucan oligosaccharide, derived from yeast cell walls, is a polysaccharide with remarkable capacity in fortifying the immune system and serving as a prebiotic, fostering the proliferation of symbiotic microorganisms within the gastrointestinal tract. This natural compound finding valuable application in the biomedical realm, facilitating the development of functional nutraceuticals and alimentary addenda aimed at ameliorating gut wellbeing and augmenting the organism's resilience against pathogenic intruders. Synonyms: a-oligoglucan. CAS No. 27707-45-5. BOC Sciences
a-Glucosylrutin a-Glucosylrutin is a naturally occurring flavonoid compound extracted from diverse plant origins, exhibiting a multitude of advantageous traits within the biomedical field owing to its formidable antioxidant prowess and remarkable anti-inflammatory attributes. Synonyms: 4(G)-alpha-Glucopyranosyl-rutin; 130603-71-3; 2-(3,4-dihydroxyphenyl)-3-[(2S,3R,4R,5S,6R)-3,4-dihydroxy-5-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxy-5,7-dihydroxychromen-4-one; Glu-rutin; alphaG-rutin; alpha G-Rutin; alpha-glucosylrutin; SCHEMBL1566365; DTXSID20156634; EC 424-170-4; 3-((O-6-Deoxy-alpha-L-mannopyranosyl-(1-6)-O-(alpha-D-glucopyranosyl-(1-4))-beta-D-glucopyranosyl)oxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one; 3-(6-O-(6-Desoxy-alpha-L-mannopyranosyl-O-(alpha-D-glucopyranosyl)-(beta-D-glucopyranosyl)oxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one, 3-((O-6-deoxy-alpha-L-mannopyranosyl-(1-6)-O-(alpha-D-glucopyranosyl-(1-4))-beta-D-glucopyranosyl)oxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-. CAS No. 130603-71-3. Molecular formula: C33H40O21. Mole weight: 772.66. BOC Sciences
agmatidine Agmatidine is a compound, finding application in the biomedical realm for studying assorted ailments comprising cancer and inflammation. Its exceptional attributes encompass anti-inflammatory and anti-carcinogenic effects, rendering it a propitious contender for pharmaceutical development. Synonyms: Agmatidine; agm(2)C; N-(4-carbamimidamidobutyl)-4-imino-1-(beta-D-ribofuranosyl)-1,4-dihydropyrimidin-2-amine; 1221169-70-5; RD252EB5W3; CHEBI:64329; DTXSID701029783; Q4692957; N-(4-Carbamimidamidobutyl)-4-imino-1-(beta-D-ribofuranosyl)-1,4-dihydro-2-pyrimidinamine; GUANIDINE, N-(4-((1,4-DIHYDRO-4-IMINO-1-.BETA.-D-RIBOFURANOSYL-2-PYRIMIDINYL)AMINO)BUTYL)-; N-(4-((1,4-DIHYDRO-4-IMINO-1-.BETA.-D-RIBOFURANOSYL-2-PYRIMIDINYL)AMINO)BUTYL)GUANIDINE. Molecular formula: C14H22N7O4. Mole weight: 356.4. BOC Sciences
agmatinase This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. The systematic name of this enzyme class is agmatine amidinohydrolase. Other names in common use include agmatine ureohydrolase, and SpeB. This enzyme participates in urea cycle and metabolism of amino groups. Group: Enzymes. Synonyms: agmatine ureohydrolase; SpeB. Enzyme Commission Number: EC 3.5.3.11. CAS No. 37289-16-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4513; agmatinase; EC 3.5.3.11; 37289-16-0; agmatine ureohydrolase; SpeB. Cat No: EXWM-4513. Creative Enzymes
agmatine deiminase The plant enzyme also catalyses the reactions of EC 2.1.3.3 (ornithine carbamoyltransferase), EC 2.1.3.6 (putrescine carbamoyltransferase) and EC 2.7.2.2 (carbamate kinase), thus functioning as a putrescine synthase, converting agmatine and ornithine into putrescine and citrulline, respectively. Group: Enzymes. Synonyms: agmatine amidinohydrolase. Enzyme Commission Number: EC 3.5.3.12. CAS No. 37289-17-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4514; agmatine deiminase; EC 3.5.3.12; 37289-17-1; agmatine amidinohydrolase. Cat No: EXWM-4514. Creative Enzymes
agmatine kinase L-Arginine can act as acceptor, but more slowly. Group: Enzymes. Synonyms: phosphagen phosphokinase; ATP:agmatine 4-N-phosphotransferase. Enzyme Commission Number: EC 2.7.3.10. CAS No. 9076-75-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3181; agmatine kinase; EC 2.7.3.10; 9076-75-9; phosphagen phosphokinase; ATP:agmatine 4-N-phosphotransferase. Cat No: EXWM-3181. Creative Enzymes
agmatine N4-coumaroyltransferase This enzyme belongs to the family of transferases, to be specific those acyltransferases transferring groups other than aminoacyl groups. Group: Enzymes. Synonyms: p-coumaroyl-CoA-agmatine N-p-coumaroyltransferase; agmatine coumaroyltransferase; 4-coumaroyl-CoA:agmatine 4-N-coumaroyltransferase. Enzyme Commission Number: EC 2.3.1.64. CAS No. 85030-72-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2244; agmatine N4-coumaroyltransferase; EC 2.3.1.64; 85030-72-4; p-coumaroyl-CoA-agmatine N-p-coumaroyltransferase; agmatine coumaroyltransferase; 4-coumaroyl-CoA:agmatine 4-N-coumaroyltransferase. Cat No: EXWM-2244. Creative Enzymes
Agmatine sulfate Agmatine sulfate exerts modulatory action at multiple molecular targets, such as neurotransmitter systems, ion channels and nitric oxide synthesis. It is an endogenous agonist at imidazoline receptor and a NO synthase inhibitor. Uses: Scientific research. Group: Natural products. CAS No. 2482-00-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-101238. MedChemExpress MCE
Agmatine sulfate [1-Amino-4-guanidinobutane.sulfate. CAS No. 2482-00-0. Product ID: 8-01456. Molecular formula: C5H14N4.H2SO4. Mole weight: 228.27. CarboMer Inc
Agmatine Sulfate Agmatine Sulfate. Group: Biochemicals. Alternative Names: N-(4-aminobutyl)guanidine Sulfate; NIH 11035. Grades: Highly Purified. CAS No. 2482-00-0. Pack Sizes: 1g. Molecular Formula: C5H16N4O4S, Molecular Weight: 228.27. US Biological Life Sciences. USBiological 3
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Agmatine Sulfate Agmatine Sulfate. Categories: agmatine sulfate; 2482-00-0. Pharma Resources International LLC
CA, FL & NJ
Agmatine Sulfate-[d8] A labelled analogue of Agmatine sulfate salt. Agmatine sulfate, the sulfate preparation of Agmatine, is an endogenous agonist at imidazoline receptor and a NO synthase inhibitor. Agmatine displaces clonidine at α2-adrenergic and at imidazoline receptors and produces blockade of the NMDA-receptor associated cation channels. Synonyms: 4-Aminobutyl-d8 Guanidine Sulfate; (4-Aminobutyl-d8)guanidine Sulfate; 1-Amino-4-guanidinobutane-d8 Sulfate; 4-Guanidino-1-butanamine-d8 Sulfate; N-(4-Aminobutyl)guanidine-d8 Sulfate; NSC 56332-d8 Sulfate. Grades: > 98%. CAS No. 909556-32-7. Molecular formula: C5H8D8N4O4S. Mole weight: 236.32. BOC Sciences
Agmatine sulfate endogenous agonist at Agmatine sulfate endogenous agonist at. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AGMATINE SULFATE ENDOGENOUS AGONIST AT;1-(4-aminobutyl)guanidine;2-(4-aminobutyl)guanidine;(4-Aminobutyl) guanidine;N1-(4-Aminobutyl)guanidine;2-(4-azanylbutyl)guanidine;4-Guanidino-1-butanamine;N-(4-Aminobutyl)guanidine. Product Category: Heterocyclic Organic Compound. CAS No. 306-60-5. Molecular formula: C5H14N4. Mole weight: 130.19146. Density: 1.2. Product ID: ACM306605. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 3
Agmatine Sulfate ≥93% (HPLC) Agmatine Sulfate ≥93% (HPLC). Group: Biochemicals. Alternative Names: N-(4-aminobutyl)guanidine Sulfate; NIH 11035. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g. US Biological Life Sciences. USBiological 4
Worldwide
Agmatine sulfate salt Agmatine sulfate, the sulfate preparation of Agmatine, is an endogenous agonist at imidazoline receptor and a NO synthase inhibitor. Agmatine displaces clonidine at α2-adrenergic and at imidazoline receptors and produces blockade of the NMDA-receptor associated cation channels. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: 2-(4-aminobutyl)guanidine;sulfuric acid. Grades: ≥ 93 % (HPLC). CAS No. 2482-00-0. Molecular formula: C5H16N4O4S. Mole weight: 228.27. BOC Sciences
AGN 192403 hydrochloride The hydrochloride salt form of AGN 192403, which has been found to show high affinity to imidazoline I1 receptor. Synonyms: AGN-192403 hydrochloride, AGN192403 hydrochloride, AGN 192403 hydrochloride, AGN-192403 HCl; (±)-2-endo-Amino-3-exo-isopropylbicyclo[2.2.1]heptane hydrochloride. Grades: ≥95% by HPLC. CAS No. 1021868-90-5. Molecular formula: C10H19N.HCl. Mole weight: 189.73. BOC Sciences
AGN 192403 hydrochloride AGN 192403 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1021868-90-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
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Agn 193109 Agn 193109. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-[2-[5,6-Dihydro-5,5-dimethyl-8-(4-methylphenyl)-2-naphthalenyl]ethynyl]benzoic Acid; CD 3106. Product Category: Heterocyclic Organic Compound. Appearance: Off-White Solid. CAS No. 171746-21-7. Molecular formula: C28H24O2. Mole weight: 392.49. Purity: 0.96. IUPACName: 4-[2-[5,5-dimethyl-8-(4-methylphenyl)-6H-naphthalen-2-yl]ethynyl]benzoic acid. Density: 1.21 g/cm³. Product ID: ACM171746217. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 3
AGN 193109 AGN 193109 is a retinoid analog, and acts as a specific and highly effective antagonist of retinoic acid receptors (RARs) , with K d s of 2 nM, 2 nM, and 3 nM for RARα , RARβ , and RARγ , respectively. AGN 193109 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. AGN 193109 is the antidote for retinoic acidosis, that ameliorates the skin and mucosal toxicity. Uses: Scientific research. Group: Signaling pathways. CAS No. 171746-21-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00449. MedChemExpress MCE
AGN 193109 AGN 193109 has been found to be a pan-retinoic acid receptor (RAR) antagonist. Synonyms: AGN 193109; AGN193109; AGN-193109; 4-[2-[5,6-Dihydro-5,5-dimethyl-8-(4-methylphenyl)-2-naphthalenyl]ethynyl]benzoic acid. Grades: ≥97% by HPLC. CAS No. 171746-21-7. Molecular formula: C28H24O2. Mole weight: 392.49. BOC Sciences 2
AGN 193109-d7 A labeled retinoic acid receptor (RAR) antagonist used for treating chemotherapy and radiation therapy side effects. Group: Biochemicals. Alternative Names: 4- [2- [5, 6-Dihydro-5, 5-dimethyl-8- (4-methylphenyl-d7) -2-naphthalenyl] ethynyl] benzoic Acid; CD 3106-d7. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 1
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AGN 193109-d7 Ethyl Ester Precursor to labeled AGN 193109. Group: Biochemicals. Alternative Names: 4- [2- [5, 6-Dihydro-5, 5-dimethyl-8- (4-methylphenyl-d7) -2-naphthalenyl] ethynyl] benzoic Acid Ethyl Ester. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 1
Worldwide
Agn 193109 ethyl ester Agn 193109 ethyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-[2-[5,6-Dihydro-5,5-dimethyl-8-(4-methylphenyl)-2-naphthalenyl]ethynyl]benzoic Acid Ethyl Ester. Product Category: Heterocyclic Organic Compound. Appearance: Pale Yellow Solid. CAS No. 171568-43-7. Molecular formula: C30H28O2. Mole weight: 420.54. Purity: 0.96. IUPACName: ethyl 4-[2-[5,5-dimethyl-8-(4-methylphenyl)-6H-naphthalen-2-yl]ethynyl]benzoate. Product ID: ACM171568437. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 3
AGN 193109 Ethyl Ester Precursor to AGN 193109. Group: Biochemicals. Alternative Names: 4- [2- [5, 6-Dihydro-5, 5-dimethyl-8- (4-methylphenyl) -2-naphthalenyl] ethynyl] benzoic Acid Ethyl Ester. Grades: Highly Purified. CAS No. 171568-43-7. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 1
Worldwide
AGN 193109 Sodium Salt A retinoic acid receptor (RAR) antagonist used for treating chemotherapy and radiation therapy side effects. Group: Biochemicals. Alternative Names: 4- [2- [5, 6-Dihydro-5, 5-dimethyl-8- (4-methylphenyl) -2-naphthalenyl] ethynyl] benzoic Acid Sodium Salt; CD 3106 Sodium Salt. Grades: Highly Purified. CAS No. 171746-21-7(freebase). Pack Sizes: 1mg. US Biological Life Sciences. USBiological 1
Worldwide
AGN 193109 Sodium Salt AGN 193109 is a potent antagonist of retinoic acid receptors (RARs, Kd = 2, 2, and 3 nM for RARα, β, and γ, respectively). Synonyms: 4-[2-[5,6-dihydro-5,5-dimethyl-8-(4-methylphenyl)-2-naphthalenyl]ethynyl]-benzoic acid monosodium salt; CD 3106 Sodium Salt; Benzoic acid, 4-[2-[5,6-dihydro-5,5-dimethyl-8-(4-methylphenyl)-2-naphthalenyl]ethynyl]-, sodium salt (1:1); sodium 4-((5,5-dimethyl-8-(p-tolyl)-5,6-dihydronaphthalen-2-yl)ethynyl)benzoate. Grades: 95%. Molecular formula: C28H23NaO2. Mole weight: 414.47. BOC Sciences
AGN 194310 A high affinity pan-RAR antagonist (AGN194310, K(d) for binding to RARs=2-5 nM) inhibited colony formation (by 50%) by all three lines at 16-34 nM, and led to a transient accumulation of flask-cultured cells in G1 followed by apoptosis. AGN194310 is 12-22 fold more potent than all-trans retinoic acid (ATRA) against cell lines and also more potent in inhibiting the growth of primary prostate carcinoma cells. The administration of all-trans retinoic acid to VAD mice resulted in a transient reduction in NF-kappaB activity and, conversely, a single dose of the RAR-pan-antagonist, AGN 194310, administered to control mice, led to a marked, transient induction of whole-body luminescence. Mice were treated with AGN194310, a synthetic retinoid that antagonises the physiological function of the three RAR isotypes (alpha, beta, gamma) but does not interact with RXRs. Analyses of the granulocytic lineage using Gr-1, c-Kit and CD11b antibodies, demonstrated that granulocyte numbers were strikingly increased across haemopoietic compartments in all AGN194310-treated mice. A significant increase in the frequency of progenitor cells containing granulocytes was observed in the bone marrow of mice following treatment with AGN194310. Synonyms: AGN194310; AGN-194310; VTP194310; VTP 194310; VTP-194310. Grades: >98%. CAS No. 229961-45-9. Molecular formula: C28H24O2S. Mole weight: 424.55. BOC Sciences 2
AGN 195183 RX-195183 is an RARα agonist (Kd=3 nM) with potential antineoplastic activity, modulating the transcription of genes responsible for cell differentiation and proliferation. Uses: Rarα agonist. Synonyms: IRX5183; IRX-5183; IRX 5183; NRX195183; NRX-195183; NRX 195183; VTP-195183; VTP195183; VTP 195183; AGN-195183; AGN195183; AGN195183.; 4-[(4-chloro-3-hydroxy-5,5,8,8-tetramethyl-6,7-dihydronaphthalene-2-carbonyl)amino]-2,6-difluorobenzoic acid. Grades: ≥98%. CAS No. 367273-07-2. Molecular formula: C22H22ClF2NO4. Mole weight: 437.87. BOC Sciences 2
AGN 196996 AGN 196996 is a potent and selective antagonist of RAR&alpha. It has been reported to selectively bind to RARs (retinoic acid receptors) for RARα, RARβ and RAR&gamma. It can inhibit the gene transcription activity which induced by ATRA and other RAR agonists. It shows no activity in transactivation assays, but instead block the gene transcriptional activity induced by ATRA and other RAR agonists. Grades: >98%. CAS No. 958295-17-5. Molecular formula: C24H20BrNO5. Mole weight: 482.32. BOC Sciences 2
AGN 203818 AGN 203818 is an α2-adrenergic receptor antagonist that can be used to treat fibromyalgia-associated pain. Synonyms: 2H-Imidazole-2-thione, 4-[1-(2,3-dimethylphenyl)ethyl]-1,3-dihydro-, hydrochloride (1:1); 4-[1-(2,3-Dimethylphenyl)ethyl]-1,3-dihydro-2H-imidazole-2-thione hydrochloride (1:1); AGN203818; AGN-203818; AGN 203818 hydrochloride. Grades: ≥95%. CAS No. 1021954-16-4. Molecular formula: C13H16N2S.HCl. Mole weight: 268.81. BOC Sciences 2
AGN 205728 AGN 205728 is a potent and selective RARγ antagonist and has no inhibiton on RARα and RAR&beta. Synonyms: AGN 205728; AGN205728; AGN-205728. Grades: >98%. CAS No. 859498-05-8. Molecular formula: C29H27NO3. Mole weight: 437.53. BOC Sciences 2
Agnuside Agnuside. Group: Biochemicals. Alternative Names: Agnoside; Buddlejoside A. Grades: Plant Grade. CAS No. 11027-63-7. Pack Sizes: 10mg. Molecular Formula: C22H26O11, Molecular Weight: 466.435. US Biological Life Sciences. USBiological 8
Worldwide
Agnuside Agnuside is used in the study of asthma, inflammation, and angiogenic diseases. Agnuside is an orally active compound that can be extracted from Vitex negundo [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Agnoside. CAS No. 11027-63-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N2518. MedChemExpress MCE
Agomelatine Agomelatine. Group: Biochemicals. Alternative Names: N-[2-(7-Methoxynaphth-1-yl)ethyl]acetamide; S20098. Grades: Highly Purified. CAS No. 138112-76-2. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C15H17NO2. US Biological Life Sciences. USBiological 6
Worldwide
Agomelatine Agomelatine (S-20098) is a specific agonist of MT1 and MT2 receptors with K i s of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively [1]. Agomelatine is a selective 5-HT2C receptor antagonist with pK i s of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively [2]. Uses: Scientific research. Group: Natural products. Alternative Names: S-20098. CAS No. 138112-76-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17038. MedChemExpress MCE
Agomelatine Agomelatine is a melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression. Agomelatine (S20098) displayed pKi values of 6.4 and 6.2 at native (porcine) and cloned, human (h)5-hydroxytryptamine (5-HT)2C receptors, respectively. Synonyms: AGO 178; AGO-178; AGO178; N-(2-(7-methoxy-1-naphthyl)ethyl)acetamide; S 20098; S-20098; S20098. trade names: Valdoxan, Melitor, Thymanax. Grades: 0.99. CAS No. 138112-76-2. Molecular formula: C15H17NO2. Mole weight: 243.31. BOC Sciences
Agomelatine 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C15H17NO2. CAS No. 138112-76-2. Prepack ID 54855684-1g. Molecular Weight 243.3. See USA prepack pricing. Molekula Americas
Agomelatine N-(2-(7-Methoxy-1-naphthalenyl)ethyl)acetamide. CAS No. 138112-76-2. Product ID: 8-04503. Molecular formula: C15H17NO2. Mole weight: 243.31. Purity: 0.99. Source : Protein kinase inhibitor. CarboMer Inc
Agomelatine-[d3] Agomelatine-[d3] is the labelled analogue of Agomelatin, which is a melatoninergic agonist and selective 5-HT2C receptor antagonist. It is used as an atypical antidepressant in the treatment of major depressive disorder. Synonyms: Agomelatine-D3 (acetamide-2,2,2-D3); Valdoxan-d3; Thymanax-d3; N-(2-(7-Methoxynaphthalen-1-yl)ethyl)acetamide-d3; Melitor-d3. Grades: 95% by HPLC; 98% atom D. CAS No. 1079389-38-0. Molecular formula: C15H14D3NO2. Mole weight: 246.32. BOC Sciences
Agomelatine-d6 Agomelatine-d6 is labelled Agomelatine (A430000) which is a melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression. Agomelatine (S20098) displayed pKi values of 6.4 and 6.2 at native (porcine) and cloned, human (h)5-hydroxytryptamine (5-HT)2C receptors, respectively. Group: Biochemicals. Grades: Highly Purified. CAS No. 1079389-42-6. Pack Sizes: 1mg. Molecular Formula: C15H11D6NO2, Molecular Weight: 249.34. US Biological Life Sciences. USBiological 4
Worldwide
Agomelatine hydrochloride The hydrochloride salt form of Agomelatine that is an antidepressant agent for acting as an antagonism of the 5-HT2C receptor. It is also an antagonist of 5-HT2B receptors. IC50: 6.2 and 6.6 for 5-HT2c and 5-HT2b respectively (pKi ). Uses: The hydrochloride salt form of agomelatine that is an antidepressant agent for acting as an antagonism of the 5-ht2c receptor. Synonyms: Valdoxan hydrochloride; S-20098 hydrochloride; S 20098 hydrochloride; S20098 hydrochloride. Grades: 98%. CAS No. 1176316-99-6. Molecular formula: C15H18ClNO2. Mole weight: 279.76. BOC Sciences
Agomelatine hydrochloride Agomelatine hydrochloride (S-20098 hydrochloride) is a specific agonist of MT1 and MT2 receptors with K i s of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively [1]. Agomelatine hydrochloride is a selective 5-HT2C receptor antagonist with pK i s of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively [2]. Uses: Scientific research. Group: Natural products. Alternative Names: S-20098 hydrochloride. CAS No. 1176316-99-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17038A. MedChemExpress MCE
Agomelatine Impurity 1 An analogue of Agomelatine. Synonyms: N-[2-(7-methoxy-3,4-dihydro-naphthalen-1-yl)ethyl]. Grades: > 95%. CAS No. 1352139-51-5. Molecular formula: C15H19NO2. Mole weight: 245.32. BOC Sciences
Agomelatine Impurity 1 Agomelatine Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (E)-2-(7-methoxy-3,4-dihydronaphthalen-1(2H)-ylidene)acetonitrile. CAS No. 178676-65-8. Molecular Formula: C13H13NO. Mole Weight: 199.25. Catalog: APB178676658. Alfa Chemistry Analytical Products
Agomelatine impurity 10 Agomelatine impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N,N-bis(2-(7-methoxynaphthalen-1-yl)ethyl)acetamide. CAS No. 1385018-58-5. Molecular Formula: C28H29NO3. Mole Weight: 427.53. Catalog: APB1385018585. Alfa Chemistry Analytical Products 2
Agomelatine impurity 11 Agomelatine impurity 11. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: bis(2-(7-methoxynaphthalen-1-yl)ethyl)amine. CAS No. 1385018-57-4. Molecular Formula: C26H27NO2. Mole Weight: 385.50. Catalog: APB1385018574. Alfa Chemistry Analytical Products 2
Agomelatine impurity 12 Agomelatine impurity 12. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(7-methoxynaphthalen-1-yl)acetonitrile. CAS No. 138113-08-3. Molecular Formula: C13H11NO. Mole Weight: 197.23. Catalog: APB138113083. Alfa Chemistry Analytical Products 2
Agomelatine impurity 13 Agomelatine impurity 13. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(7-methoxynaphthalen-1-yl)ethan-1-aminehydrochloride. CAS No. 139525-77-2. Molecular Formula: C13H15NO. Mole Weight: 201.26. Catalog: APB139525772. Alfa Chemistry Analytical Products
Agomelatine Impurity 14 Agomelatine Impurity 14. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N,N-bis(2-(7-methoxynaphthalen-1-yl)ethyl)nitrous amide. Molecular Formula: C26H26N2O3. Mole Weight: 414.50. Catalog: APB02531. Alfa Chemistry Analytical Products 3
Agomelatine Impurity 15 Agomelatine Impurity 15. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(2-(7-hydroxynaphthalen-1-yl)ethyl)acetamide. CAS No. 152302-45-9. Molecular Formula: C14H15NO2. Mole Weight: 229.27. Catalog: APB152302459. Alfa Chemistry Analytical Products
Agomelatine Impurity 16 Agomelatine Impurity 16. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(2-(7-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)ethyl)acetamide. CAS No. 178677-49-1. Molecular Formula: C15H21NO2. Mole Weight: 247.33. Catalog: APB178677491. Alfa Chemistry Analytical Products
Agomelatine Impurity 17 Agomelatine Impurity 17. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-acetyl-N-(2-(7-methoxynaphthalen-1-yl)ethyl)acetamide. CAS No. 1379005-34-1. Molecular Formula: C17H19NO3. Mole Weight: 285.34. Catalog: APB1379005341. Alfa Chemistry Analytical Products 2

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