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| Product | Description | |
|---|---|---|
| Afelimomab | Afelimomab (MAK 195F) is an anti-tumor necrosis factor F(ab')2 monoclonal antibody fragment. Afelimomab can be used for the research of sepsis [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MAK 195F. CAS No. 156227-98-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99425. |  |
| AFG206 | AFG206 is the novel first-generation "type II" FLT3 inhibitor. Synonyms: AFG-206; AFG 206. Grades: >98%. CAS No. 630122-37-1. Molecular formula: C20H19N3O2. Mole weight: 333.38. |  |
| AFG210 | AFG210 is a novel first-generation "type II" FLT3 inhibitor. Synonyms: AFG 210; AFG-210; 1-(3-(trifluoromethyl)phenyl)-3-(4-(pyridin-4-yloxy)phenyl)urea. Grades: >98%. CAS No. 228400-22-4. Molecular formula: C19H14F3N3O2. Mole weight: 373.33. | |
| Aficamten | Aficamten, also known as CK-3773274 and CK-274, is a Next-Generation Cardiac Myosin Inhibitor for the Treatment of Hypertrophic Cardiomyopathy. Aficamten was designed to provide a predicted human half-life (t1/2) appropriate for once a day (qd) dosing, to reach steady state within two weeks, to have no substantial cytochrome P450 induction or inhibition, and to have a wide therapeutic window in vivo with a clear pharmacokinetic/pharmacodynamic relationship. In a phase I clinical trial, aficamten demonstrated a human t1/2 similar to predictions and was able to reach steady state concentration within the desired two-week window. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CK-3773274; CK3773274; CK 3773274; CK-274; CK274; CK 274. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2364554-48-1. Molecular formula: C18H19N5O2. Mole weight: 337.38. Purity: >98%. IUPACName: N-[(1R)-5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl]-1-methyl-1H-pyrazole-4-carboxamide. Canonical SMILES: O=C(C1=CN(C)N=C1)N[C@@H]2CCC3=C2C=CC(C4=NOC(CC)=N4)=C3. Product ID: ACM2364554481. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Aficamten | Aficamten (CK-274) is a potent cardiac myosin inhibitor with an IC 50 of 1.4 μM. Aficamten can be used for the research of hypertrophic cardiomyopathy (HCM) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CK-274; CK-3773274. CAS No. 2364554-48-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139465. | |
| Afimetoran | Afimetoran (BMS-986256) is an orally active, selective, and highly bioavailable TLR7/8 antagonist. Afimetoran (BMS-986256) can inhibit TLR7/8 activation of the NF-κB pathway and reverse TLR7 mediated resistance to steroid induced apoptosis in plasma cell like dendritic cells (pDCs). Afimetoran (BMS-986256) can be used for research on inflammation and autoimmune diseases (systemic lupus erythematosus) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-986256. CAS No. 2171019-55-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139567. | |
| Afimoxifene | Afimoxifene (4-hydroxytamoxifen) is a selective estrogen receptor modulator which is the active metabolite of tamoxifen. Afimoxifene is a transdermal gel formulation and is being developed by Ascend Therapeutics, Inc. under the trademark TamoGel. Afimoxifene has completed a phase II clinical trial for the treatment of cyclical mastalgia. Uses: Estrogen antagonists. Synonyms: (E/Z)-4-Hydroxytamoxifen; 4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol; TamoGel; Phenol, 4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-. Grades: ≥95%. CAS No. 68392-35-8. Molecular formula: C26H29NO2. Mole weight: 387.51. | |
| Aflastatin A | It is produced by the strain of Streptomyces sp. MRI 142. Aflatoxin A has anti-Gram-positive bacteria, Pyricularia oryzae and yeast activity (MIC is 0.19-0.39 μg/mL), and inhibits the growth of adenocarcinoma 755 (1.0 mg/kg reduces tumor growth by 75% the above). Synonyms: 2,4-Pyrrolidinedione, 1, 5-dimethyl-3-(1, 8, 9, 11, 13, 15, 17, 19, 21, 23, 25, 27, 28, 29, 30, 31-hexadecahydroxy-2, 4, 6, 10, 12, 14, 18, 20-octamethyl-32-(tetrahydro-3, 4, 5, 6-tetrahydroxy-6-(2-hydroxyundecyl)-2H-pyran-2-yl)-2-dotriacontenylidene)-; LS-137668. Grades: ≥ 95%. CAS No. 179729-59-0. Molecular formula: C62H115NO24. Mole weight: 1258.56. | |
| Aflatoxicol | The 2 ppm acetonitrile solution of aflatoxicol, a metabolite of aflatoxin, could be commonly used as a standard solution. Uses: Only to be used as a reference standard in analytical laboratories. Synonyms: Aflatoxin Ro; (1S-(1alpha, 6abeta, 9abeta))-2, 3, 6a, 9a-Tetrahydro-1-hydroxy-4-methoxycyclopenta(c)furo(3', 2':4, 5)furo(2, 3-h)(1)benzopyran-11(1H)-one; Cyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-11(1H)-one, 2,3,6a,9a-tetrahydro-1-hydroxy-4-methoxy-, (1S,6aR,9aS)-; AFL. Grades: ≥98%. CAS No. 29611-03-8. Molecular formula: C17H14O6. Mole weight: 314.29. | |
| Aflatoxicol | Aflatoxin (Aflatoxin R0) is a metabolite of aflatoxin B1 produced from Rhizopus spp [1] , and is mutagenic and carcinogenic mycotoxin [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Aflatoxin R0. CAS No. 29611-03-8. Pack Sizes: 1 mg. Product ID: HY-N6695. | |
| AFLATOXICOL I NATURAL ISOMER VACUUM DRIED | AFLATOXICOL I NATURAL ISOMER VACUUM DRIED. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (1R,6aS,9aS)-1-Hydroxy-4-methoxy-2,3,6a,9a-tetrahydrocyclopenta[c]furo[3,2:4,5]furo[2,3-h]chromen-11(1H)-one. Product Category: Heterocyclic Organic Compound. CAS No. 29611-03-8. Molecular formula: C17H14O6. Mole weight: 314.289. Purity: 0.96. IUPACName: Aflatoxicol A. Density: 1.56g/cm³. Product ID: ACM29611038. Alfa Chemistry ISO 9001:2015 Certified. | |
| Aflatoxin B1-[13C17] | Aflatoxin B1-[13C17] is the labelled analogue of Aflatoxin B1, which is an aflatoxin produced by Aspergillus flavus and A. parasiticus. Synonyms: Aflatoxin B1-13C17. Grades: 95% atom 13C. CAS No. 1217449-45-0. Molecular formula: [13C]17H12O6. Mole weight: 329.15. | |
| Aflatoxin B1 aldehyde reductase member 2 from Human, Recombinant | Aflatoxin B1 aldehyde reductase member 2 catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Has NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2-nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). Can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro). Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen. Group: Enzymes. Synonyms: AFB1 aldehyde reductase 1; AFB1-AR 1; Aldoketoreductase 7; Succinic semialdehyde reductase. Enzyme Commission Number: EC 1.1.1.n11. AKR7A2. Mole weight: 39588.9 Da. Source: Human. AFB1 aldehyde reductase 1; AFB1-AR 1; Aldoketoreductase 7; Succinic semialdehyde reductase; EC 1.1.1.n11; AKR7A2; Aflatoxin B1 aldehyde reductase member 2. Cat No: NATE-1196. |  |
| Aflatoxin B2 | Aflatoxins B1, B2, G1, G2 as secondary metabolites of fungal species such as Aspergillus flavus or Aspergillus parasiticus growing on a variety of foods (peanuts, nuts, spices, cereals). Aflatoxins are a group of very carcinogenic mycotoxins with hepatotoxic effects. Group: Biochemicals. Alternative Names: (6aR, 9aS) -2, 3, 6a, 8, 9, 9a-Hexahydro-4-methoxycyclopenta [c]furo [3, 2: 4, 5]furo [2, 3-h] [1]benzopyran-1, 11-dione; Dihydroaflatoxin B1; Dihydroaflatoxine B1. Grades: Highly Purified. CAS No. 7220-81-7. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences. |  Worldwide |
| Aflatoxin (BSA) | Aflatoxins belong to the class of mycotoxins. Toxic fungal metabolite and carcinogen. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| aflatoxin B synthase | A heme-thiolate (P-450) enzyme. Isolated from the mold Aspergillus parasiticus. Group: Enzymes. Synonyms: ordA (gene name); 8-O-methylsterigmatocystin,NADPH:O2 oxidoreductase (aflatoxin-B forming). Enzyme Commission Number: EC 1.14.13.175. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0773; aflatoxin B synthase; EC 1.14.13.175; ordA (gene name); 8-O-methylsterigmatocystin,NADPH:O2 oxidoreductase (aflatoxin-B forming). Cat No: EXWM-0773. | |
| Aflatoxin G1 | Aflatoxin G1 is the major analogue of the green fluorescent family of bisfuranocoumarin mycotoxins produced by Aspergillus flavus and related species. Alfatoxins are one of the most potent mycotoxins known but are in fact "pre-toxins" requiring metabolic activation to the toxic principle. Aflatoxins are found widely in nature in trace amounts particularly grains and nuts. The toxicity of these metabolites was first recognised in the 1950s and their structures elucidated in 1963. Aflatoxins have been extensively reviewed. Source:Aflatoxin G1 from Aspergillus flavus. Group: Biochemicals. Alternative Names: (7aR, 10aS)-3, 4, 7a, 10a-Tetrahydro-5-methoxy-1H, 12H-furo[3, 2:4, 5]furo[2, 3-h]pyrano[3, 4-c][1]benzopyran-1, 12-dione. Grades: Highly Purified. CAS No. 1165-39-5. Pack Sizes: 1mg, 5mg. Molecular Formula: C17H12O7, Molecular Weight: ~328.3. US Biological Life Sciences. | Worldwide |
| Aflatoxin G2 | Aflatoxins B1, B2, G1, G2 as secondary metabolites of fungal species such as Aspergillus flavus or Aspergillus parasiticus growing on a variety of foods (peanuts, nuts, spices, cereals). Aflatoxins are a group of very carcinogenic mycotoxins with hepatotoxic effects. Group: Biochemicals. Alternative Names: (7aR, 10aS)-3, 4, 7a, 9, 10, 10a-Hexahydro-5-methoxy-1H, 12H-furo[3', 2':4, 5]furo[2, 3-h]pyrano[3, 4-c][1]benzopyran-1, 12-dione. Grades: Highly Purified. CAS No. 7241-98-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Aflatoxin M1 | An Aspergillus flavus metabolite. Aflatoxin M1 in milk as a secondary metabolite of the Aflatoxin B1 formed in moldy forages. It is cancerogenic, hepatotoxic, and immunosuppressive in animals and man. Group: Biochemicals. Alternative Names: (6aR, 9aR)-2, 3, 6a, 9a-Tetrahydro-9a-hydroxy-4-methoxy-cyclopenta[c]furo[3, 2:4, 5]furo[2, 3-h][1]benzopyran-1, 11-dione; AFM1. Grades: Highly Purified. CAS No. 6795-23-9. Pack Sizes: 250ug. US Biological Life Sciences. | Worldwide |
| Aflatoxin M1 | It is produced by the strain of Aspergillus flavus, Asp. parasiticus. The compound of aflatoxin has the activity of anti-gram-positive bacteria, inhibits cell mitosis, has the effect of liver necrosis and carcinogenesis, and is a mycotoxin which contaminates food. Synonyms: AFLATOXIN M1; 4-Hydroxyaflatoxin B1; 3020O28I3; CCRIS 15; (6aR, 9aR)-9a-hydroxy-4-methoxy-2, 3, 6a, 9a-tetrahydrocyclopenta[c]furo[3', 2':4, 5]furo[2, 3-h]chromene-1, 11-dione; (6aR-cis)-2, 3, 6a, 9a-tetrahydro-9a-hydroxy-4-methoxycyclopenta[c]furo[3', 2':4, 5]furo[2, 3-h][1]benzopyran-1, 11-dione; CHEBI:78576; Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione,2,3,6a,9a-tetrahydro-9a-hydroxy-4-methoxy-,(6ar,9ar)-. Grades: ≥95%. CAS No. 6795-23-9. Molecular formula: C17H12O7. Mole weight: 328.27. | |
| Aflatoxin Q1 | Aflatoxin Q1 is a metabolite of Aflatoxin B1. It is created in human body as a in-vivo detoxification process of Aflatoxin B1. Uses: A metabolite of aflatoxin b1; a hepatocarcinogen in many animal models and probably a human carcinogen. it is produced by the predominant forms of cytochrome p 450 enzymes responsible for the biotransformation of afb1. it shows potential predictive value. Synonyms: Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-3-hydroxy-4-methoxy-, (3S,6aR,9aS)-; Cyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-3-hydroxy-4-methoxy-, (3S-(3-alpha,6a-alpha,9a-alpha))-; (3S, 6aR, 9aS)-3-hydroxy-4-methoxy-2, 3, 6a, 9a-tetrahydrocyclopenta[c]furo[3', 2':4, 5]furo[2, 3-h]chromene-1, 11-dione. Grades: ≥98%. CAS No. 52819-96-2. Molecular formula: C17H12O7. Mole weight: 328.27. | |
| Aflatrem | Aflatrem is the secondary metabolite of Aspergillus flavus. It is able to induce degeneration of neuronal processes in hippocampal neurotransmitter systems at low dose. It potentiates the gamma-aminobutyric acid (GABA)-induced chloride current. It is a tremorgenic mycotoxin with acute neurotoxic effect. Synonyms: 4H-3,15a-Epoxy-1-benzoxepino[6',7':6,7]indeno[1,2-b]indol-4-one, 9-(1,1-dimethyl-2-propenyl)-2,3,5b,6,7,7a,8,13,13b,13c,14,15-dodecahydro-5b-hydroxy-2,2,13b,13c-tetramethyl-, (3R,5bS,7aS,13bS,13cR,15aS)-; 9-(1, 1-Dimethyl-2-propenyl)-2, 3, 5b, 6, 7, 7aα, 8, 13, 13b, 13c, 14, 15-dodecahydro-5bβ-hydroxy-2, 2, 13bβ, 13cα-tetramethyl-4H-3β, 15aβ-epoxy-1-benzoxepino[6', 7':6, 7]indeno[1, 2-b]indol-4-one; α,α-dimethylallylpaspalinine. Grades: 98.0%. CAS No. 70553-75-2. Molecular formula: C32H39NO4. Mole weight: 501.66. | |
| Aflavarin | Aflavarin is a metabolite of the Sclerotia of Aspergillus flavus displaying anti-insectan activity against the fungivorous beetle Carpopbilus bemipterus. Synonyms: (3,8'-Bi-2H-1-benzopyran)-2,2'-dione, 5-(hydroxymethyl)-4,4',7,7'-tetramethoxy-5'-methyl-, (-)-; (-)-5-(Hydroxymethyl)-4,4',7,7'-tetramethoxy-5'-methyl[3,8'-bi-2H-1-benzopyran]-2,2'-dione. Grades: 98.0%. CAS No. 144429-67-4. Molecular formula: C24H22O9. Mole weight: 454.43. | |
| Aflavazole | Aflavazole is a metabolite of the sclerotia of Aspergillus flavus. It shows antifeedant activity against the fungivorous beetle Carpophilus hemipterus remarkably. Synonyms: (1R,4S,4aS,13dS,14R,16R,16aS)-1,2,3,4,5,6,9,13d,14,15,16,16a-Dodecahydro-1,7,14,16a-tetramethylphenanthro[2,1-c]carbazole-4,16-diol; (+)-Aflavazole; Benzo(4a,5)naphtho(2,1-c)carbazole-4,16-diol, 1,2,3,4,5,6,9,13d,14,15,16,16a-dodecahydro-1,7,14,16a-tetramethyl-, (1alpha, 4alpha, 4aS*, 13dbeta, 14alpha, 16beta, 16aalpha)-(+)-; Benzo(4a,5)naphtho(2,1-c)carbazole-4,16-diol,1,2,3,4,5,6,9,13d,14,15,16,16a-dodecahydro-1,7,16a-tetramethyl-, (1R,4S,4aS,13dS,14R,16R,16aS)-rel-(+)-. Grades: 97.5%. CAS No. 2043963-70-6. Molecular formula: C28H35NO2. Mole weight: 417.58. | |
| Aflibercept | Aflibercept is a recombinant fusion protein and acts as a VEGF inhibitor. Aflibercept is used for the treatment of wet macular degeneration and metastatic colorectal cancer. Synonyms: Eylea. CAS No. 862111-32-8. Molecular formula: C4318H6788N1164O1304S32. Mole weight: 96898.57. | |
| Aflibercept | Aflibercept (VEGF Trap) is a soluble decoy VEGFR constructed by fusing the Ig domains of VEGFR 1 and VEGFR 2 with the Fc region of human IgG1. Aflibercept inhibits VEGF signaling by reducing VEGF-regulated processes. Aflibercept can be used for thr research of age-related macular degeneration (AMD) and cardiovascular disease [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: VEGF Trap; VEGF-TRAPR1R2; VEGF-trapR1. CAS No. 862111-32-8. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-108801. | |
| Aflibercept (VEGF Trap) | Aflibercept (VEGF Trap) is a soluble decoy VEGFR constructed by fusing the Ig domains of VEGFR 1 and VEGFR 2 with the Fc region of human IgG1. Aflibercept inhibits VEGF signaling by reducing VEGF-regulated processes. Aflibercept can be used for thr research of age-related macular degeneration (AMD) and cardiovascular disease [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 862111-32-8. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-108801A. | |
| Afloqualone | Afloqualone is a agonist of GABA receptor has sedative and muscle-relaxant effects. Uses: A agonist of gaba receptor. Synonyms: HQ-495; HQ495; HQ 495. Afloqualone; 6-amino-2-(fluoromethyl)-3-(2-methylphenyl)quinazolin-4-one. Grades: ≥98%. CAS No. 56287-74-2. Molecular formula: C16H14FN3O. Mole weight: 283.3. | |
| Afloqualone | Afloqualone (HQ-495) is an orally active central muscle relaxant and antivertiginous agent that can increase the sensitivity of GABA receptors in neurons of the lateral vestibular nucleus. Afloqualone (HQ-495) can be used in the research of low back pain and neck-arm-shoulder syndrome [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HQ-495. CAS No. 56287-74-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1833. | |
| Afloqualone Impurity 1 | Afloqualone Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 136426-54-5. Molecular Formula: C16H8Cl2FN5O. Mole Weight: 376.17. Catalog: APB136426545. |  |
| a-Fluoro-b-alanine | a-Fluoro-b-alanine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| a-Fluoro-b-alanine-13C3 ((2R)-3-Amino-2-fluoropropanoic Acid-13C3) | A stable isotope analogue of the catabolism of the anti-cancer drug 5-Flurouracil. Group: Biochemicals. Alternative Names: (2R)-3-Amino-2-fluoropropanoic Acid-13C3. Grades: Highly Purified. CAS No. 1246819-54-4. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| a-Fluorophenylacetonitrile | a-Fluorophenylacetonitrile. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-FLUOROBENZYL CYANIDE 97%;Jrd-0527. Product Category: Heterocyclic Organic Compound. CAS No. 10036-43-8. Molecular formula: C8H6NF. Mole weight: 135.14. Product ID: ACM10036438. Alfa Chemistry ISO 9001:2015 Certified. Categories: 501-00-8. | |
| a-Fmoc-L-Lys((+)-Biotinyl-e-aminocaproyl)-OH 99+% | a-Fmoc-L-Lys((+)-Biotinyl-e-aminocaproyl)-OH 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| AFN-1252 | AFN-1252 is an enoyl-(acyl-carrier protein) reductase fabl inhibitor, inhibited all clinical isolates of Staphylococcus aureus and Staphylococcus epidermidis at concentrations of ≤0.12 μg/ml. Uses: Antibacterial. Synonyms: AFN-1252; AFN 1252; AFN1252; AFN-12520000; API-1252; Debio-1452; AFN12520000; API1252; Debio1452. (E)-N-methyl-N-[(3-methyl-1-benzofuran-2-yl)methyl]-3-(7-oxo-6,8-dihydro-5H-1,8-naphthyridin-3-yl)prop-2-enamide. Grades: ≥95%. CAS No. 620175-39-5. Molecular formula: C22H21N3O3. Mole weight: 375.43. | |
| AFN-1252 | AFN-1252, also known as AFN-12520000; API-1252; Debio-1452, is FASII Inhibitor which is potentially for the treatment of acute bacterial skin. AFN-1252 exhibits typical MIC(90) values of ≤0·015 μg/ml against diverse clinical isolates of S. aureus, oral absorption, long elimination half-live and efficacy in animal models. AFN-1252 efficiently blocked daptomycin-induced phospholipid decoy production, even in the case of isolates resistant to AFN-1252, which prevented the inactivation of daptomycin and resulted in sustained bacterial killing. In turn, daptomycin prevented the fatty acid-dependent emergence of AFN-1252-resistant isolates in vitro. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AFN-1252; AFN 1252; AFN1252; API-1252; API1252; API 1252; AFN12520000; AFN 12520000; AFN12520000; Debio1452; Debio 1452; Debio1452. Product Category: Inhibitors. Appearance: White to off-white solid powder. CAS No. 620175-39-5. Molecular formula: C22H21N3O3. Mole weight: 375.43. Purity: >98%. IUPACName: (E)-N-methyl-N-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide. Canonical SMILES: O=C(N(C)CC1=C(C)C2=CC=CC=C2O1)/C=C/C3=CC(CC4)=C(N=C3)NC4=O. Product ID: ACM620175395. Alfa Chemistry ISO 9001:2015 Certified. | |
| AFN39186 | AFN39186, also known as RAD51-IN-1, is a derivative of B02 and a potent inhibitor of RAD51. AFN39186 was first reported in Bioorg Med Chem Lett. 2017 Jul 15;27(14):3096-3100. This product has no formal name at the moment. Uses: Designed for use in research and industrial production. Additional or Alternative Names: RAD51-IN-1; AFN39186; AFN-39186; AFN 39186. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2101739-18-6. Molecular formula: C22H16ClN3O. Mole weight: 373.84. Purity: >98%. IUPACName: (E)-3-(4-chlorobenzyl)-2-(2-(pyridin-3-yl)vinyl)quinazolin-4(3H)-one. Canonical SMILES: O=C1N(CC2=CC=C(Cl)C=C2)C(/C=C/C3=CC=CN=C3)=NC4=C1C=CC=C4. Product ID: ACM2101739186. Alfa Chemistry ISO 9001:2015 Certified. | |
| Afobazole | Fabomotizole (brand name Afobazole) is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Fabomotizole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Clinical trials have shown fabomotizole to be well tolerated and reasonably effective for the treatment of anxiety. Experiments of mice have showed antimutagenic and antiteratogenic properties. Synonyms: CM346; Afobazol; Fabomotizole; CM 346; CM-346. Grades: >98%. CAS No. 173352-21-1. Molecular formula: C15H21N3O2S. Mole weight: 307.41. | |
| Afobazole hydrochloride | Fabomotizole (brand name Afobazole) is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Fabomotizole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Clinical trials have shown fabomotizole to be well tolerated and reasonably effective for the treatment of anxiety. Experiments of mice have showed antimutagenic and antiteratogenic properties. Synonyms: CM346 hydrochloride; Afobazol hydrochloride; Fabomotizole hydrochloride; CM 346 hydrochloride; CM-346 hydrochloride. Grades: >98%. CAS No. 173352-39-1. Molecular formula: C15H22ClN3O2S. Mole weight: 343.87. | |
| Afoxolaner | Afoxolaner is an orally active isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect γ-aminobutyric acid receptor (GABA) and glutamate receptors , inhibiting GABA & glutamate-regulated uptake of chloride ions , resulting in excess neuronal stimulation and death of the arthropod [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1093861-60-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16974. | |
| Afoxolaner | Afoxolaner is an insecticide and acaricide used in dogs to treat and prevent flea infestations. Used to treat specifically the Sarcoptes scabiei var. canis species. Group: Biochemicals. Grades: Highly Purified. CAS No. 1093861-60-9. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C26H17ClF9N3O3, Molecular Weight: 625.87. US Biological Life Sciences. | Worldwide |
| Afoxolaner | Afoxolaner is a potent isoxazoline insecticide and acaricide against Ixodes scapularis in dogs. It is indicated for the treatment and prevention of flea infestations, and the treatment and control of tick infestations in dogs and puppies. It is administered orally in meat-flavoured tablets, and poisons fleas once they start feeding. It is used either alone or as a combination treatment with milbemycin oxime. Synonyms: 4-[5-[3-Chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-1-naphthalenecarboxamide; 4-[5-[3-Chloro-5- (trifluoromethyl) phenyl]-5- (trifluoromethyl) -4H-1, 2-oxazol-3-yl]-N-[2-oxo-2- (2, 2, 2-trifluoroethylamino) ethyl]naphthalene-1-carboxamide. Grades: >98%. CAS No. 1093861-60-9. Molecular formula: C26H17ClF9N3O3. Mole weight: 625.87. | |
| afoxolaner Impurity 1 | afoxolaner Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C26H19ClF9N3O4. Mole Weight: 643.89. Catalog: APB12362. | |
| afoxolaner Impurity 2 | afoxolaner Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C26H15ClF9N3O2. Mole Weight: 607.86. Catalog: APB12363. | |
| afoxolaner Impurity 3 | afoxolaner Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C26H18ClF9N2O4. Mole Weight: 628.88. Catalog: APB12364. | |
| afoxolaner Impurity 4 | afoxolaner Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C24H15ClF6N2O4. Mole Weight: 544.83. Catalog: APB12365. | |
| afoxolaner Impurity 5 | afoxolaner Impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1308362-48-2. Molecular Formula: C22H12ClF6NO3. Mole Weight: 487.78. Catalog: APB1308362482. | |
| AFP 07 | AFP 07 is a 7,7-difluoroprostacyclin derivative that acts as a selective and highly potent agonist for the IP receptor. Synonyms: (5Z)-5-[(3aR,4R,5R,6aS)-3,3-difluoro-5-hydroxy-4-[(E,3S,4S)-3-hydroxy-4-methylnon-1-en-6-ynyl]-4,5,6,6a-tetrahydro-3aH-cyclopenta[b]furan-2-ylidene]pentanoic acid. Grades: ≥98%. CAS No. 788799-13-3. Molecular formula: C22H30F2O5. Mole weight: 412.5. | |
| AFP-464 | AFP-464 is a synthetic lysyl prodrug of the amino-substituted flavone derivate aminoflavone with antiproliferative and antineoplastic activities. AFP464 is rapidly converted to aminoflavone in plasma. Aminoflavone activates the aryl hydrocarbon receptor (AhR) signaling pathway leading to an increase in cytochrome P450 1A1 (CYP1A1) and cytochrome P450 1A2 (CYP1A2) expression and, to a lesser extent, an increase in cytochrome P450 1B1 (CYP1B1) expression. Synonyms: AFP464; AFP 464; Hexanamide, 2,6-diamino-N-(4-(5-amino-6,8-difluoro-7-methyl-4-oxo-4H-1-benzopyran-2-yl)-2-fluorophenyl)-, (2S)-. CAS No. 468719-52-0. Molecular formula: C23H27F3N4O6S. Mole weight: 448.44. | |
| Afragilimycin A | It is produced by the strain of Streptomyces neohygroscopicus sub-sp, afragilimycetius 19255. It has anti-gram-positive bacteria and anti-gram-negative bacteria including anaerobic bacteria activity. Synonyms: Afrigilimycin A; (2S)-4-[(2E,4E,6R)-6-[(1S,2S,3R,5S,6R)-2,5-dimethylspiro[4,9-dioxabicyclo[3.3.1]non-7-ene-6,2'-oxirane]-3-yl]-4-methylhepta-2,4-dienoyl]-1-[(5S,6S)-5-hydroxy-6-methyloxan-2-yl]-2-[(2S)-1-(methylamino)-1-oxopropan-2-yl]-3-oxo-2H-pyrrol-5-olate. CAS No. 76559-69-8. Molecular formula: C32H43N2O9-. Mole weight: 599.69. | |
| African Mango Seed Extract | African Mango Seed Extract. Applications: Used for health care products, dietary supplements, weight loss, reducing blood lipids. Group: Others. Synonyms: African Mango Seed Extract; 9005-80-5; Irvingia GabonensisSeed. CAS No. 9005-80-5. Purity: 20% Phytoprotein By KJELDAHL, 10:1 By TLC. Appearance: Light yellow fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Seed. Species: Irvingia GabonensisSeed. African Mango Seed Extract; 9005-80-5; Irvingia GabonensisSeed; plant extract. Pack: 20KG-25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-103. | |
| African Mango Seed P.E. 10:1 | African Mango Seed P.E. 10:1 (Irvingia Gabonensis). |  CA, FL & NJ |
| Afromosin | Afromosin is an isoflavone, that can be isolated from Millettia dielsiana Harms. Afromosin exhibits remarkable tumor inhibitory effects [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 550-79-8. Pack Sizes: 1 mg. Product ID: HY-119846. | |
| Afrormosin | Afrormosin is found in the herbs of Mucuna macrocarpa Wallich. Synonyms: Afrormosine. Grades: > 95%. CAS No. 550-79-8. Molecular formula: C17H14O5. Mole weight: 298.29. | |
| Aftin-4 (N6-Methyl-(R)-roscovitine, Amyloid-beta Forty-Two Inducer 4) | Roscovitine-related purine with no activity on CDKs (used as control for roscovitine). Selectively and potently increases production of extracellular Abeta42 and decreases production of extracellular Abeta38 in cultured cells. Extracellular Abeta40 levels remain stable. Intracellular levels of these amyloids appear to remain stable. Alzheimer's Disease (AD) accelerator that interacts with VDAC1, prohibitin and mitofilin, possibly interfering with subcellular compartmentalization and lipid rafts properties, shifting gamma-secretase activity toward Abeta42 generation. Induces a reversible mitochondrial phenotype reminiscent of the one observed in AD brains. Tool to detect inhibitors of Aftin-induced actions (potential anti-AD compounds). Binds pyridoxal kinase. Group: Biochemicals. Grades: Highly Purified. CAS No. 866893-90-5. Pack Sizes: 1mg, 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| Aftin-5 ((2R)-2-[[9-Isopropyl-6-(N-methylanilino)purin-2-yl]amino]butan-1-ol, Amyloidbeta Forty-Two Inducer 5) | Roscovitine-related purine with no activity on CDKs (used as control for roscovitine). Selectively and potently increases production of extracellular Ab42 and decreases production of extracellular Ab38 in cultured cells. Extracellular Ab40 levels remain stable. Intracellular levels of these amyloids appear to remain stable. Alzheimer's Disease (AD) accelerator that interacts with VDAC1, prohibitin and mitofilin, possibly interfering with subcellular compartmentalization and lipid rafts properties, shifting gamma-secretase activity toward Ab42 generation. Induces a reversible mitochondrial phenotype reminiscent of the one observed in AD brains. Tool to detect inhibitors of Aftin-induced actions (potential anti-AD compounds). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| Aftobetin Hydrochloride | Aftobetin, also known as ANCA11 and NCE-11, is a novel amyloid-binding compound applied topically in the form of an ophthalmic ointment. Aftobetin may be of useful as an aid in the diagnosis Alzheimer's disease. Synonyms: Aftobetin Hydrochloride; NCE-11; Aftobetin Hydrochloride [USAN]; UNII-A1FCZ940WA; 1353222-83-9; A1FCZ940WA; 11-HCl; 2-Propenoic acid, 2-cyano-3-(6-(1-piperidinyl)-2-naphthalenyl)-, 2-(2-(2-methoxyethoxy)ethoxy)ethyl ester, hydrochloride (1:1), (2E)-; Aftobetin hydrochloride (USAN); 2-(2-(2-Methoxyethoxy)ethoxy)ethyl (2E)-2-cyano-3-(6-(piperidin-1-yl)naphthalen-2-yl)prop-2-enoate monohydrochloride; Aftobetin HCl; 2-[2-(2-Methoxyethoxy)ethoxy]ethyl (2E)-2-cyano-3-[6-(piperidin-1-yl)naphthalen-2-yl]prop-2-enoate monohydrochloride; aftobetin-hydrochloride; ANCA-11 HYDROCHLORIDE; CHEMBL2364602; DTXSID90159314; AKOS040750170; AFTOBETIN HYDROCHLORIDE [WHO-DD]; D10607; Q27273497. CAS No. 1353222-83-9. Molecular formula: C26H33ClN2O5. Mole weight: 489.009. | |
| Afuresertib | Afuresertib, also known as GSK2110183, is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor GSK2110183 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signaling may contribute to tumor resistance to a variety of antineoplastic agents. Synonyms: GSK-2110183; GSK 2110183; GSK2110183; GSK-2110183B; GSK 2110183B; GSK2110183B; Afuresertib. CAS No. 1047644-62-1. Molecular formula: C18H17Cl2FN4OS. Mole weight: 427.32. | |
| Afuresertib | Afuresertib (GSK2110183) is an orally bioavailable, selective, ATP-competitive and potent pan-Akt kinase inhibitor with K i s of 0.08/2/2.6 nM for Akt1/Akt2/Akt3, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK2110183; LAE002. CAS No. 1047644-62-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15727. | |
| Afuresertib HCl | Afuresertib HCl is a potent pan-AKT inhibitor. Synonyms: N-((S)-1-amino-3-(3-fluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide hydrochloride; GSK2110183; GSK 2110183; GSK-2110183; GSK2110183B; GSK 2110183B; GSK2110183B; Afuresertib. Grades: >98%. CAS No. 1047645-82-8. Molecular formula: C18H18Cl3FN4OS. Mole weight: 463.78. | |
| Afuresertib hydrochloride | Afuresertib hydrochloride (GSK 2110183 hydrochloride) is an orally bioavailable, selective, ATP-competitive and potent pan-Akt kinase inhibitor with K i s of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK2110183 hydrochloride; LAE002 hydrochloride. CAS No. 1047645-82-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15727A. | |
| Afutuzumab | Afutuzumab. Uses: Designed for use in research and industrial production. Additional or Alternative Names: afutuzumab;Ga 101;Humab(cd20);Ro 5072759;Ro5072759. Product Category: Heterocyclic Organic Compound. CAS No. 949142-50-1. Product ID: ACM949142501. Alfa Chemistry ISO 9001:2015 Certified. | |
| Afuzosin EP Impurity A | Afuzosin EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-[3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)methylamino]propyl]furan-2-carboxamide. Molecular Formula: C19H23N5O4. Mole Weight: 385.42. Catalog: APB03232. | |
| Afuzosin EP Impurity D | Afuzosin EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N2-(3-aminopropyl)-6,7-dimethoxy-N2-methylquinazolin-2,4-diamine. Molecular Formula: C14H21N5O2. Mole Weight: 291.35. Catalog: APB03229. | |
| Afuzosin EP Impurity E | Afuzosin EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-[3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)methylamino]propyl]formamide. Molecular Formula: C15H21N5O3. Mole Weight: 319.36. Catalog: APB03228. | |
| Afuzosin EP Impurity F | Afuzosin EP Impurity F. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6,7-dimethoxy-N2,N2-dimethylquinazoline-2,4-diamine. Molecular Formula: C12H16N4O2. Mole Weight: 248.28. Catalog: APB03227. | |
| Afuzosin EP Impurity G | Afuzosin EP Impurity G. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N2-[3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)amino]propyl]-6,7-dimethoxy-N2-methylquinazoline-2,4-diamine. Molecular Formula: C24H30N8O4. Mole Weight: 494.55. Catalog: APB03226. | |
| Afuzosin hydrochloride | Afuzosin hydrochloride. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2RS)-N-[3-[(4-Amino-6,7-dimethoxyquinazolin-2-yl)methylamino]propyl]oxolan-2-carboxamide hydrochloride. Molecular Formula: C19H27N5O4. Mole Weight: 389.45. Catalog: APB03234. | |
| Afzelin | Afzelin. Group: Biochemicals. CAS No. 482-39-3. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Ag | Ag. Group: Elements nanoparticles. 99.9%. |  |
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