A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
A cyclic nucleotides with protein kinase and phosphodiesterase activity. Group: Biochemicals. Alternative Names: 5-Aminoimidazole-4-carboxamide-1- β-D-ribofuranosyl 3:5-cyclic-monophosphate;5-Amino-1-(3,5-O-phosphinico- β-D-ribofuranosyl)-1H-imidazole-4-carboxamide; NSC 371796. Grades: Highly Purified. CAS No. 35908-14-6. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
AICAR-5'-MP / ZMP
AICAR-5'-MP is an analogue of AICA-riboside, an alternative of 5'-AMP. AICAR-5'-MP is a purine precursor with antineoplastic activity and can be used in the study of type 2 diabetes. It can activate AMP-activated protein kinase. Synonyms: 1H-Imidazole-4-carboxamide, 5-amino-1-(5-O-phosphono-β-D-ribofuranosyl)-; 5-Amino-1-(5-O-phosphono-β-D-ribofuranosyl)-1H-imidazole-4-carboxamide; Imidazole-4-carboxamide, 5-amino-1-β-D-ribofuranosyl-, 5'-(dihydrogen phosphate); Imidazole-4-carboxamide, 5-amino-1-β-D-ribofuranosyl-, 5'-phosphate; 5-Amino-1-(5'-phosphofuranoribosyl)-4-imidazolecarboxamide; 5-Amino-1β-D-ribofuranosylimidazole-4-carboxamide 5'-phosphate; 5-Amino-4-imidazolecarboxamide ribonucleoside 5'-monophosphate; 5-Amino-4-imidazolecarboxamide ribonucleotide; 5-Amino-4-imidazolecarboxamide riboside 5'-monophosphate; 5-Amino-4-imidazolecarboxamide ribotide; 5-Aminoimidazole-4-carboxamide ribonucleotide; 5'-Phospho-β-D-ribosyl-5-amino-4-imidazolecarboxamide; 5'-Phosphoribosyl-5-amino-4-imidazolecarboxamide; Acadesine 5'-monophosphate; AICA Ribotide; AICA-Ribonucleotide; AICAR; AICAR monophosphate; AICAR (5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 5'-monophosphate); Aminoimidazolecarboxamide ribonucleotide; NSC 283955; NSC 292227; ZMP; ZMP (alarmone). Grades: ≥95%. CAS No. 3031-94-5. Molecular formula: C9H15N4O8P. Mole weight: 338.21.
AICA-Riboside, 5?-Phosphate - CAS 3031-94-5
A 5'-phosphorylated analog of membrane permeable AICA-Riboside that mimics AMP and acts as an activator of AMPK (AMP-activated protein kinase). Group: Fluorescence/luminescence spectroscopy.
AICAR phosphate
AICAR phosphate (Acadesine phosphate) is an adenosine analog and a AMPK activator. AICAR phosphate regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR phosphate is also an autophagy , YAP and mitophagy inhibitor [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Acadesine phosphate; AICA Riboside phosphate. CAS No. 681006-28-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13417A.
AICAR phosphate
AICAR phosphate, is an AMP-activated protein kinase activator, which is used for the treatment of acute lymphoblastic leukemia and may have applications in treating other disorders such as diabetes. It stimulates glucose uptake and increases the activity of p38 mitogen-activated protein kinases α and β in skeletal muscle tissue, as well as suppressing apoptosis by reducing production of reactive oxygen compounds inside the cell. Synonyms: Acadesine phosphate; AICA Riboside phosphate. Grades: >98%. CAS No. 681006-28-0. Molecular formula: C9H17N4O9P. Mole weight: 356.23.
AIDA
AIDA is a selective group I mGluR agonist and could show centrally active following systemic administration in vivo. Uses: Excitatory amino acid antagonists. Synonyms: (RS)-1-Aminoindan-1,5-dicarboxylic acid. Grades: ≥98% by HPLC. CAS No. 168560-79-0. Molecular formula: C11H11NO4. Mole weight: 221.21.
A relatively potent and selective antagonist for group I mGlu receptor subtype 1 (pKB = 3.4 for mGlu1a). Complete absence of interacting with on group II or III mGluRs, or ionotropic glutamate receptors. Widely used in studying neural plasticity, learning and memory, and fear conditioning. Centrally active following systemic administration in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 168560-79-0. Pack Sizes: 5mg. Molecular Formula: C??H??NO?. US Biological Life Sciences.
Ailanthone (Δ13-Dehydrochaparrinone) is a potent inhibitor of both full-length androgen receptor (AR) ( IC 50 =69?nM) and constitutively active truncated AR splice variants (AR 1-651 IC 50 =309?nM). Uses: Scientific research. Group: Natural products. Alternative Names: Δ13-Dehydrochaparrinone. CAS No. 981-15-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1943.
Ailanthone
Botanical Source: Group: Biochemicals. Grades: Plant Grade. CAS No. 981-15-7. Pack Sizes: 10mg. US Biological Life Sciences.
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AIM 100
AIM 100. Group: Biochemicals. Grades: Purified. CAS No. 873305-35-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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AIM-100
AIM-100 is a potent and selective Ack1 tyrosine kinase with IC50 value of 24 nM. AIM-100, not only inhibited Ack1 activation but also able to suppress pTyr267-AR phosphorylation, binding of AR to PSA, NKX3.1, and TMPRSS2 promoters, and inhibit AR transcription activity. Ack1 tyrosine kinase activation correlates with pancreatic cancer progression. Ack1 inhibitors hold promise for therapeutic intervention to inhibit pancreatic tumor growth. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AIM-100; AIM 100; AIM100. Product Category: Others. Appearance: Solid powder. CAS No. 873305-35-2. Molecular formula: C23H21N3O2. Mole weight: 371.44. Purity: >98%. IUPACName: N-[[(2S)-oxolan-2-yl]methyl]-5,6-diphenylfuro[2,3-d]pyrimidin-4-amine. Canonical SMILES: C12=NC=NC(NC[C@H]3OCCC3)=C1C(C4=CC=CC=C4)=C(C5=CC=CC=C5)O2. Product ID: ACM873305352. Alfa Chemistry ISO 9001:2015 Certified.
AIM-100
AIM-100 is a small molecule inhibitor of Ack1. It not only inhibited Ack1 activation but also suppressed AKT tyrosine phosphorylation, leading to cell cycle arrest in the G1 phase. It could suppress AR Tyr(267) phosphorylation and its recruitment to the ATM enhancer and suppress pTyr267-AR phosphorylation, binding of AR to PSA, NKX3.1, and TMPRSS2 promoters, and inhibit AR transcription activity. Synonyms: AIM-100; AIM 100; AIM100. Grades: >98%. CAS No. 873305-35-2. Molecular formula: C23H21N3O2. Mole weight: 371.43.
a-Ionone
a-Ionone. Group: Biochemicals. Alternative Names: (3E)-4-(2,6,6-Trimethyl-2-cyclohexen-1-yl)3-buten-2-one; (5E)-Ionone; (E)-4-(2,6,6-Trimethyl-2-cyclohexen-1-yl)-3-buten-2-one. Grades: Highly Purified. CAS No. 127-41-3. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C13H20O. US Biological Life Sciences.
Worldwide
AITRL human
AITRL, a cytokine belonging to the tumor necrosis factor (TNF) ligand superfamily, is expressed in endothelial cells, and signals through the AITR receptor. AITRL regulates T-cell proliferation and survival, and effectuates the interaction between T lymphocytes and endothelial cells. AITRL is a ligand for receptor TNFRSF18/AITR/GITR. GITR/AITRL interaction plays a role in the pathogenesis of tumors, inflammation, and autoimmune diseases. In addition, AITRL is involved in endothelial cell (EC) activation and increases STAT-1 phosphorylation and the expression of adhesion molecules (VCAM-1, ICAM-1). Synonyms: Activation-induced TNFR member Ligand; TNFSF18; rHuActivation-inducible TNF-related Ligand/AITRL; GITRL; TL-6; Tumor necrosis factor ligand superfamily member 18; rHuAITRL; GITR Ligand. Grades: ≥98% by HPLC. Mole weight: ~14.3 kDa.
AITRL human
recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
AJ2-30
AJ2-30 is a SLCl5A4 inhibitor. AJ2-30 inhibits endolysosomal TLR7-9-mediated mTOR activation. AJ2-30 blocks endogenous NOD signaling. AJ2-30 can be used in inflammation studies[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2700322-79-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-155864.
AJI-9561
AJI-9561 is a benzoxazole derivative produced by Streptomyces sp. AJ9561. It has cytotoxic activity with IC50 of 0.88 μmol/L and 1.63 μmol/L for Jorkat and P388 cells, respectively. Its mechanism of action is the same as that of UK-1, which can inhibit DNA topoisomerase U. Synonyms: (2,4'-Bibenzoxazole)-4-carboxylic acid, 2'-(2-hydroxy-6-methylphenyl)-. CAS No. 339300-34-4. Molecular formula: C22H14N2O5. Mole weight: 386.36.
Ajmalicine
Ajmalicine (Raubasine) is a potent adrenolytic agent which preferentially blocks α 1 -adrenoceptor. Ajmalicine is an reversible but non-competitive nicotine receptor full inhibitor, with an IC 50 of 72.3 μM. Ajmalicine also can be used as anti-hypertensive, and serpentine, with sedative activity [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Raubasine. CAS No. 483-04-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N1919.
Ajmaline is an alkaloid which could be extracted from Rauwolfia serpentina. It is an antiarrhythmic agent, acting through changing the shreshold and the shape of cardiac action potentials. Synonyms: Cardiorythmine; Ajmalin; Gilurytmal; Raugalline. Grades: >95%. CAS No. 4360-12-7. Molecular formula: C20H26N2O2. Mole weight: 326.43.
Ajmaline
An antiarrhythmic agent isolated from Rauwolfia serpentina. Group: Biochemicals. Alternative Names: (17R,21α-Ajmalan-17,21-diol; (+)-Ajmaline; Cardiorythmine; Gilurytmal; Ignazin; Merabitol; NSC 15627; Raugalline; Rauwolfin; Rauwolfine; Rhytmaton; Ritmos; Rytmalin; Siddiqui; Tachmalin; Takycor. Grades: Highly Purified. CAS No. 4360-12-7. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Ajmaline
Ajmaline (Cardiorythmine) is a sodium channel blocking, class 1A anti-arrhythmic agent. Ajmaline blocks HERG currents with an IC 50 of 1 μM in HEK cells and 42.3 μM in Xenopus oocytes. Ajmaline can be used for the research of the ventricular tachyarrhythmia [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Cardiorythmine; (+)-Ajmaline. CAS No. 4360-12-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1167.
Ajn I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 55°C in a total reaction volume of 50 μl. Applications: 10 mm tris-hcl (ph 7.5); 100 mm nacl; 0.1 mm edta; 7 mm 2-mercaptoethanol; 200 μg/ml bsa; 50% glycerol. Group: Restriction Enzymes. Purity: 200U; 1000U. ↑CCWGG GGWCC&darr. Activity: 500-3000u.a./ml. Appearance: 10 X SE-buffer Y, BSA. Storage: -20°C. Form: Liquid. Source: Acinetobacter johnsonii R2. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: RE-1017EN.
Ajoene
Ajoene, a garlic-derived compound, is an antithrombotic and antifungal agent. Ajoene inhibits proliferation and induces apoptosis of human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-I. Anticancer activities [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 92285-01-3. Pack Sizes: 1 mg (21.33 mM * 200 μL in Ethyl acetate). Product ID: HY-106784.
AJS75
AJS75, the most adjuvant-active fraction of AJSt, could improve antigen-specific both cellular and humoral immune responses and simultaneously elicit a Th1/Th2 response by inducing cytokine and chemokine at the site of injection.
Ajugasterone C
Ajugasterone C. Group: Biochemicals. Grades: Plant Grade. CAS No. 23044-80-6. Pack Sizes: 10mg. Molecular Formula: C27H44O7, Molecular Weight: 480.63. US Biological Life Sciences.
Worldwide
Ajugasterone C
Ajugasterone C is a steroid found in the herbs of Ajuga ciliata Bunge. Grades: >98%. CAS No. 23044-80-6. Molecular formula: C27H44O7. Mole weight: 480.642.
Ajuga Turkestancia P.E. 10% Turkesterone HPLC
Ajuga Turkestancia P.E. 10% Turkesterone HPLC.
CA, FL & NJ
Ajugol
Ajugol is an iridiod glucoside isolated from the roots of Rehmannia glutinosa. Uses: An iridiod glucoside. Synonyms: (2S,3S,4R,5R,6S)-2-(hydroxymethyl)-6-{[(4aS,7S,7aR)-7-hydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-1-yl]oxy}tetrahydro-2H-pyran-2,3,4,5-tetrol. Grades: >98%. CAS No. 52949-83-4. Molecular formula: C15H24O9. Mole weight: 348.35.
Ajugol (Leonuride )
Ajugol (Leonuride ). Group: Biochemicals. Alternative Names: Ajugol; Leonuride. Grades: Plant Grade. CAS No. 52949-83-4. Pack Sizes: 20mg. Molecular Formula: C15H24O9, Molecular Weight: 348.346. US Biological Life Sciences.
AK-1 is a potent, specific and cell-permeable SIRT2 inhibitor, with an IC 50 of 12.5 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 330461-64-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101465.
AK-1
AK-1 is a potent, specific and cell-permeable SIRT2 inhibitor (IC50 = 12.5 μM) with excellent selectivity against SIRT1 and SIRT3 (IC50 >50 μM, and >50 μM for SIRT1 and SIRT3 respectively). Synonyms: AK-1; AK 1; AK1; DA-42784; KB-120200; Y1899; J-018989; DA42784; KB120200; J018989; DA 42784; KB 120200; J 018989; 3-(azepan-1-ylsulfonyl)-N-(3-nitrophenyl)benzamide; SIRT2 Inhibitor II, AK-1; SIRT2 Inhibitor II; CHEMBL1797749; 3-(azepan-1-ylsulfonyl)-N-(3-nitrophenyl)benzamide. CAS No. 330461-64-8. Molecular formula: C19H21N3O5S. Mole weight: 403.45.
AK-1690
AK-1690 is a potent and selective STAT6 PROTAC degrader. AK-1690 reduces the levels of STAT6 protein in cells (DC50=1 nM) and depletes STAT6 protein in mouse tissues. AK-1690 can be used for the research of cancer. (Pink: ligand for target protein STAT6 (HY-169182); Black: linker (HY-W459522); Blue: ligand for E3 ligase (HY-131318)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2984505-88-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-169179.
AK-2292
AK-2292 is a potent and selective STAT5 PROTAC degrader, with a DC50 of 0.10 ?M. AK-2292 induces degradation of STAT5A/B proteins in vitro and in vivo. AK-2292 can induce tumor regression in acute myeloid leukemia and chronic myeloid leukemia xenograft mouse models[1][2]. AK-2292 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2984506-77-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148813.
AK 7
AK 7. Group: Biochemicals. Grades: Purified. CAS No. 420831-40-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
AK-7 is a selective cell- and brain-permeable SIRT2 inhibitor, with an IC 50 of 15.5 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 420831-40-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16691.
AK-7
AK-7 is a selective and brain-permeable SIRT2 inhibitor, which displays no effect on SIRT1 or SIRT3. It could decrease neuronal cholesterol levels and improve motor function and ameliorates brain atrophy in a mouse model of Huntington's disease. Synonyms: AK-7; CS-3223; GL-8955; AK7; CS3223; GL8955; AK 7; CS 3223; GL 8955. Grades: >98%. CAS No. 420831-40-9. Molecular formula: C19H21BrN2O3S. Mole weight: 437.35.
AK-7
Brain-permeable SIRT2 (sirtuin 2) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 420831-40-9. Pack Sizes: 5mg, 25mg. Molecular Formula: C19H21BrN2O3S. US Biological Life Sciences.
Worldwide
AK-778-XXMU
AK-778-XXMU is a potent inhibitor of DNA Binding 2 (ID2) antagonist with a KD of 129 nM. AK-778-XXMU can inhibit cell migration and invasion of glioma cell lines, induce apoptosis, and more importantly, slow down the tumor growth[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1227045-76-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144707.
AK 7 (N-(3-Bromophenyl)-3-[(hexahydro-1H- azepin-1-yl)sulfonyl]benzamide)
Selective SIRT2 inhibitor (IC50 = 15.5um); displays no effect on SIRT1 or SIRT3. Decreases neuronal cholesterol levels; improves motor function and ameliorates brain atrophy in a mouse model of Huntington's disease. Brain penetrant. Group: Biochemicals. Grades: Highly Purified. CAS No. 420831-40-9. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
AkaLumine hydrochloride
AkaLumine hydrochloride is a D-luciferin (HY-12591A) analogue with a Km of 2.06 ?M for recombinant firefly luciferase (Fluc) protein. AkaLumine hydrochloride emits near-infrared (NIR) light (?max=677?nm) in reactions with native Fluc. AkaLumine hydrochloride has high tissue-penetration and increases detection sensitivity from deep-tissue targets[1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 2558205-28-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112641A.
Akardit II
Akardit II. Group: Biochemicals. Grades: Highly Purified. CAS No. 13114-72-2. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences.
Worldwide
Akarkara P.E. 10:1 (Anacyclus Pyrethrum)
Akarkara P.E. 10:1 (Anacyclus Pyrethrum).
CA, FL & NJ
AKB48-d11
AKB48-d11. Group: Biochemicals. Alternative Names: 1-Pentyl-N-tricyclo[3.3.1.13, 7]dec-1-yl-1H-indazole-3-carboxamide-d11. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C23H20D11N3O, Molecular Weight: 376.58. US Biological Life Sciences.
Worldwide
AKB48 N-Pentanoic Acid
AKB48 N-Pentanoic Acid. Group: Biochemicals. Alternative Names: APINACA N-Pentanoic Acid; 5-(3-((3s,5s,7s)-Adamantan-1-ylcarbamoyl)-1H-indazol-1-yl)pentanoic Acid. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C23H29N3O3, Molecular Weight: 395.49. US Biological Life Sciences.
Worldwide
AKBA
AKBA (Acetyl-11-keto-β-boswellic acid) is an active triterpenoid compound from the extract of Boswellia serrate and a novel Nrf2 activator. Uses: Scientific research. Group: Natural products. Alternative Names: Acetyl-11-keto-β-boswellic acid. CAS No. 67416-61-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N0892.
AKBA (Standard)
AKBA (Standard) is the analytical standard of AKBA. This product is intended for research and analytical applications. AKBA (Acetyl-11-keto-β-boswellic acid) is an active triterpenoid compound from the extract of Boswellia serrate and a novel Nrf2 activator. Uses: Scientific research. Group: Natural products. CAS No. 67416-61-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0892R.
Akebia saponin D
Asperosaponin VI ususlly comes from the root of Dipsacus asperoides C. Y. Cheng et T. M. Ai. Except for its antioxidant activity, treatment of U937 cells with akebia saponin D (ASD) induced apoptosis in a dose dependent manner. ASD exerted strong cytotoxicity against human and murine leukemia cells. ASD may exert apoptosis-inducing activity via induction of apoptosis through activation chiefly via the nitric oxide and apoptosis-related p53 and Bax gene expression. Uses: Antioxidant. Synonyms: Akebia saponin D; Hederagenin 3-O-alpha-L-arabinopyranosyl-28-beta-D-glucopyranosyl(1?6)-beta-D-glucopyranoside; Asperosaponin ?; Akebia saponin D(Asperosaponin VI); Dipsacaceae saponin. Grades: >98%. CAS No. 39524-08-8. Molecular formula: C47H76O18. Mole weight: 929.1.
a-Ketobutyric acid sodium salt 99+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 2013-26-5. Pack Sizes: 5g, 25g, 100g. US Biological Life Sciences.
Worldwide
a-Ketoglutaric acid disodium salt
a-Ketoglutaric acid disodium salt. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100g, 250g, 25g, 1Kg, 5Kg. US Biological Life Sciences.
Worldwide
a-Ketoglutaric Acid Disodium Salt Dihydrate
a-Ketoglutaric Acid Disodium Salt Dihydrate. Group: Biochemicals. Alternative Names: 2-Oxoglutaric acid disodium salt; Disodium 2-ketoglutarate. Grades: Highly Purified. CAS No. 305-72-6. Pack Sizes: 50g, 100g, 250g, 500g, 1Kg. Molecular Formula: C5H4Na2O5·2H2O, Molecular Weight: 226.09. US Biological Life Sciences.
Worldwide
a-Ketoglutaric acid disodium salt dihydrate 99+%
a-Ketoglutaric acid disodium salt dihydrate 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 25g, 100g, 250g, 1Kg, 5Kg. US Biological Life Sciences.
Worldwide
a-Ketoglutaric acid potassium salt
a-Ketoglutaric acid potassium salt. Group: Biochemicals. Alternative Names: 2-Oxopentanedioic acid potassium salt; Potassium hydrogen 2-ketoglutarate. Grades: Highly Purified. CAS No. 997-43-3. Pack Sizes: 25g, 50g, 100g. Molecular Formula: C?H?O?K, Molecular Weight: 184.19. US Biological Life Sciences.
Worldwide
AKI-001
AKI-001 is a potent Aurora kinase inhibitor, which exhibits low nanomolar potency against both Aurora A and Aurora B enzymes, excellent cellular potency (IC50 < 100 nM), and good oral bioavailability. Synonyms: AKI-001; AKI 001; AKI001. Grades:>98%. CAS No. 925218-37-7. Molecular formula: C21H24N4O. Mole weight: 348.45.
AKI603
AKI603 is an inhibitor of Aurora kinase A (AurA) with IC50 of 12.3 nM. It can induce senescence in chronic myeloid leukemia cells carrying the T315I mutation. AKI603 shows strong anti-proliferative activity in leukemia cells. Synonyms: AKI-603. Grades: 98%. CAS No. 1432515-73-5. Molecular formula: C19H23N9O2. Mole weight: 409.4.
A-kinase anchor protein 9 (1398-1407)
A-kinase anchor protein 9 (1398-1407) is amino acids 1398 to 1407 fragment of A-kinase anchor protein 9. AKAP-9 is a scaffolding protein that assembles several protein kinases and phosphatases on the centrosome and Golgi apparatus. Synonyms: AKAP-9 (1398-1407).
aklanonic acid methyl ester cyclase
The enzyme is involved in the biosynthesis of aklaviketone, an intermediate in the biosynthetic pathways leading to formation of several anthracycline antibiotics, including aclacinomycin, daunorubicin and doxorubicin. Group: Enzymes. Synonyms: dauD (gene name); aknH (gene name); dnrD (gene name); methyl aklanonate cyclase; methyl aklanonate-aklaviketone isomerase (cyclizing); aklaviketone lyase (decyclizing). Enzyme Commission Number: EC 5.5.1.23. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5624; aklanonic acid methyl ester cyclase; EC 5.5.1.23; dauD (gene name); aknH (gene name); dnrD (gene name); methyl aklanonate cyclase; methyl aklanonate-aklaviketone isomerase (cyclizing); aklaviketone lyase (decyclizing). Cat No: EXWM-5624.
aklanonic acid methyltransferase
The enzyme from the Gram-positive bacterium Streptomyces sp. C5 is involved in the biosynthesis of the anthracycline daunorubicin. Group: Enzymes. Synonyms: DauC; AAMT. Enzyme Commission Number: EC 2.1.1.288. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1895; aklanonic acid methyltransferase; EC 2.1.1.288; DauC; AAMT. Cat No: EXWM-1895.
aklaviketone reductase
The enzyme is involved in the synthesis of the aklavinone aglycone, a common precursor for several anthracycline antibiotics including aclacinomycins, daunorubicin and doxorubicin. The enzyme from the Gram-negative bacterium Streptomyces sp. C5 produces daunomycin. Group: Enzymes. Synonyms: dauE (gene name); aknU (gene name). Enzyme Commission Number: EC 1.1.1.362. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0279; aklaviketone reductase; EC 1.1.1.362; dauE (gene name); aknU (gene name). Cat No: EXWM-0279.
Aklavin
It is produced by the strain of Streptomyces galilaeus. It has the activity of resisting gram positive bacterium, negative bacterium, candida and ringworm. Synonyms: Aclacinomycin T; 1-Deoxypyrromycin; Aclacinomycin; Doxypyrromycin; NSC 100290; CHEBI:74351; 1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-4-((2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexapyranosyl)oxy)-, methyl ester, (1R-(1-alpha,2-beta,4-beta))-; aklavine. CAS No. 60504-57-6. Molecular formula: C30H35NO10. Mole weight: 569.60.
Aklavinone
Aklavinone is an anthracycline drug with an antitumor effect. CAS No. 16234-96-1. Molecular formula: C22H20O8. Mole weight: 412.39.
aklavinone 12-hydroxylase
The enzymes from the Gram-positive bacteria Streptomyces peucetius and Streptomyces purpurascens participate in the biosynthesis of daunorubicin, doxorubicin and rhodomycins. The enzyme from Streptomyces purpurascens is an FAD monooxygenase. Group: Enzymes. Synonyms: DnrF; RdmE; aklavinone 11-hydroxylase (incorrect). Enzyme Commission Number: EC 1.14.13.180. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0779; aklavinone 12-hydroxylase; EC 1.14.13.180; DnrF; RdmE; aklavinone 11-hydroxylase (incorrect). Cat No: EXWM-0779.
aklavinone 7-L-rhodosaminyltransferase
Isolated from the bacterium Streptomyces galilaeus. Forms a complex with its accessory protein AknT, and has very low activity in its absence. The enzyme can also use dTDP-2-deoxy-β-L-fucose. Involved in the biosynthesis of other aclacinomycins. Group: Enzymes. Synonyms: AknS/AknT; aklavinone 7-β-L-rhodosaminyltransferase; dTDP-β-L-rhodosamine:aklavinone 7-α-L-rhodosaminyltransferase. Enzyme Commission Number: EC 2.4.1.326. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2563; aklavinone 7-L-rhodosaminyltransferase; EC 2.4.1.326; AknS/AknT; aklavinone 7-β-L-rhodosaminyltransferase; dTDP-β-L-rhodosamine:aklavinone 7-α-L-rhodosaminyltransferase. Cat No: EXWM-2563.
Aklomide
Aklomide is antiprotozoal agent against coccidiosis. Synonyms: 2-chloro-4-nitrobenzamide 2-Chloro-4-nitrobenzamide aklomide 3011-89-0 Aklomix Clomide Alkomide Benzamide, 2-chloro-4-nitro- component of Aklomix component of Novastat-W. CAS No. 3011-89-0. Molecular formula: C7H5ClN2O3. Mole weight: 200.58.