A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
recombinant, expressed in E. coli, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
AHD-[2,4,5-13C3]
AHD-[2,4,5-13C3] is the labelled analogue of AHD, which is a metabolite of Nitrofuran. Synonyms: 1-Amino-imidazolidin-2,4-dione-[2,4,5-13C3]; AHD-13C3; 1-Amino-2,4-imidazolidinedione-13C3; 1-Aminoimidazolidin-2,4-dione-13C3; AHD-13C3; 1-Amino Hydantoin-13C3. Grade: 95% by HPLC; 98% atom 13C. CAS No. 957509-31-8. Molecular formula: [13C]3H5N3O2. Mole weight: 118.07.
AHK-Cu
AHK-Cu. CAS No. 682809-81-0. Product ID: CDC10-0607. Molecular formula: C15H24ClCuN6O4. Category: Cosmetic Active Peptide. Product Keywords: Cosmetic Ingredients; Active Ingredients; Cosmetic active peptide; AHK-Cu; CDC10-0607; Cosmetic active peptide; C15H24ClCuN6O4; Cosmetic Peptide; 682809-81-0. Appearance: Blue powder. Purity: 98%/99%. Application: Anti-Wrinkle and anti-aging.
AHK-Cu(1:1)
AHK-Cu(1:1). CAS No. 682809-81-0. Product ID: CDC10-0667. Category: Cosmetic Active Peptide. Product Keywords: Cosmetic Ingredients; Active Ingredients; Cosmetic Active Peptide; ; CDC10-0667; AHK-Cu(1:1); Cosmetic Active Peptide; ; 682809-81-0. Purity: 98%/99%. Applications: Anti-Wrinkle and anti-aging.
AHK Tripeptide-3
AHK Tripeptide-3 is a 3-amino acid that exhibits activity in hair growth, healing wounds and wound regeneration. Synonyms: Ala-His-Lys; L-alanyl-L-histidyl-L-lysine; alanylhistidyllysine. Grade: 98%. CAS No. 126828-32-8. Molecular formula: C15H26N6O4. Mole weight: 354.41.
Ahl I
One unit of the enzyme is the amount required to hydrolyze 1 μg of T7 DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme more than 90% of t7 dna fragments can be ligated and recut. Group: Restriction Enzymes. A↑CTAGT TGATC↓A. Appearance: 10 X SE-buffer B, BSA. Storage: -20°C. Form: Liquid. Source: Alteromonas haloplanktis SP. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: RE-1016EN.
a-Homonojirimycin
a-Homonojirimycin is a inhibitor of the enzymatic compound called glucosidase used for studying lysosomal storage diseases like Gaucher disease and Pompe disease. Synonyms: α-HNJ; (2R,3R,4R,5S,6R)-2,6-β(dihydroxymethyl)piperidine-3,4,5-triol; α-Homonojirimycin; 3,4,5-Piperidinetriol, 2,6-bis(hydroxymethyl)-, [2R-(2α,3α,4β,5α,6β)]-; (2R,3R,4R,5S,6R)-2,6-Bis(hydroxymethyl)-3,4,5-piperidinetriol; 2,6-Dideoxy-2,6-imino-D-glycero-L-gulo-heptitol; Homonojirimycin; 3,4,5-Piperidinetriol, 2,6-bis(hydroxymethyl)-, (2α,3α,4β,5α,6β)-. Grade: ≥98%. CAS No. 119557-99-2. Molecular formula: C7H15NO5. Mole weight: 193.20.
AHR-1911
AHR-1911 (10-Undecen-1-yl-Thiopseudourea Iodide;Isothiuronium) is a thiourea-based anti-inflammatory and anti-tumor agent that has an improving effect on burned skin. AHR-1911 produces histamine-like effects when injected intradermally and may reduce arterial pressure in anesthetized dogs. AHR-1911 inhibits tumor growth and reduces microsomal and C-polysome protein synthesis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 10-Undecen-1-yl-thiopseudourea iodide. CAS No. 22584-04-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-107063.
AhR Agonist V, VAF347
A cell-permeable pyrimidinylphenylamine compound that directly and reversibly targets aryl hydrocarbon receptor (AhR) with high-affinity, and induces AhR signaling. Reported to act as an immunomodulator with anti-inflammatory properties. Potently suppresses IgE secretion in B-cells with an IC50 of ~2nM, and inhibits dendritic cells-mediated T-cell proliferation and cytokine production. Further, decreases lung eosinophilia in B-cell-deficient mice, and allergic inflammation. Downregulates PU.1 transcription factor, and impairs human monocytes and Langerhans dendritic cells differentiation. Group: Biochemicals. Alternative Names: ((4-(3-Chloro-phenyl)-pyrimidin-2-yl)-(4-trifluoromethyl-phenyl)-amine). Grades: Highly Purified. CAS No. 574759-62-9. Pack Sizes: 10mg. Molecular Formula: C??H??ClF?N?, Molecular Weight: 349.7. US Biological Life Sciences.
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AhR Agonist V, VAF347
The AhR Agonist V, VAF347 controls the biological activity of AhR. This small molecule/inhibitor is primarily used for Biochemicals applications. Group: Fluorescence/luminescence spectroscopy.
AHR antagonist 2
AHR antagonist 2 is a potent aryl hydrocarbon receptor (AHR) antagonist, extracted from patent WO2019101641A1, compound example 1. Synonyms: AHR antagonist 2; 2338747-54-7; SCHEMBL21001701; CSSGBPKFVJOAIZ-LBPRGKRZSA-N; AKOS040732400; MS-27306; HY-135831; CS-0114332; N-[(2S)-1-hydroxypropan-2-yl]-2-pyridin-3-yl-6-[4-(trifluoromethoxy)phenyl]pyrimidine-4-carboxamide. Grade: 99%. CAS No. 2338747-54-7. Molecular formula: C20H17F3N4O3. Mole weight: 418.37.
AHR antagonist 4
AHR antagonist 4 is a potent aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1 (example 293; IC50 = 82.2 nM). It has anti-cancer effects. CAS No. 2242465-58-1. Molecular formula: C20H14F6N4O4. Mole weight: 488.34.
AHR Antagonist 5
AHR Antagonist 5, an effective and orally active aromatic hydrocarbon receptor (AHR) antagonist with IC50 of less than 0.5 μM. It can significantly inhibit tumor growth in combination with the checkpoint inhibitor anti-PD-1. Synonyms: BCP33104; HY-136220; CS-0120848; (R)-N-(2-(5-Fluoropyridin-3-Yl)-8-Isopropylpyrazolo[1,5-A][1,3,5]Triazin-4-Yl)-2,3,4,9-Tetrahydro-1H-Carbazol-3-Amine Trihydrochloride. Grade: ≥98% by HPLC. CAS No. 2247953-39-3. Molecular formula: C25H27Cl3FN7. Mole weight: 550.9.
AHR antagonist 5 free base
AHR antagonist 5 free base, a selective and orally active aryl hydrocarbon receptor (AHR) inhibitor, effectively blocks AHR from translocating from the cytoplasm to the nucleus. AHR antagonist 5 free base is highly selective for AHR over other receptors, transporters, and kinases. CAS No. 2247950-42-9. Molecular formula: C25H24FN7. Mole weight: 441.50.
AHR antagonist 5 hemimaleate
AHR antagonist 5 hemimaleate is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist with an IC50 of < 0.5 μΜ. AHR antagonist 5 hemimaleate significantly inhibits tumor growth combined with checkpoint inhibitor anti-PD-1. Molecular formula: C29H28FN7O4. Mole weight: 499.55.
AhR Antagonist III, GNF351
AhR Antagonist III, GNF351, is a cell-permeable, high-affinity aryl hydrocarbon receptor (AhR) antagonist (IC50 = 62 nM in mouse liver cytosol expressing humanized AhR). Group: Fluorescence/luminescence spectroscopy.
AhR Antagonist III, GNF351 (N-(2-(3H-Indol-3-yl)ethyl)-9-isopropyl-2-(5-methyl-3-pyridyl)-7H-purin-6-amine, N-(2-(1H-Indol-3-yl)ethyl)-9-isopropyl-2-(5-methylpyridin-3-yl)-9H-purin-6-amine)
A cell-permeable purine compound that acts as a high-affinity aryl hydrocarbon receptor (AhR) antagonist (IC50 = 62nM in mouse liver cytosol expressing humanized AhR) and lacks any agonist activity even at higher doses. Reportedly binds with high affinity to the ligand-binding pocket of AhR and blocks the binding of an array of exogenous and endogenous ligands. Shown to non-covalently interact with Ser317, His291, and Ser365 in human and with Ser311, His285, and Ser359 in mouse AhR. Represses AhR transcriptional activity via the dioxin response element (DRE)-dependent and independent mediated responses in human and mouse cells (IC50 = 8.5nM in HepG2 40/6 cells). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
AhR modulator-1
AhR modulator-1 is a selective and orally active aryl hydrocarbon receptor (AhR) modulator with anti-estrogenic properties in rat uterus. It inhibits metastasis in part by inhibiting prostatic VEGF production prior to tumor formation. Synonyms: 6-Methyl-1,3,8-trichlorodibenzofuran; MCDF; 6-MCDF; Dibenzofuran, 6-methyl-1,3,8-trichloro-; 1,3,8-Trichloro-6-methyldibenzo[b,d]furan. Grade: ≥90%. CAS No. 118174-38-2. Molecular formula: C13H7Cl3O. Mole weight: 285.55.
AHU-377 hemicalcium salt
LCZ696 is a novel single molecule comprising molecular moieties of valsartan and NEP inhibitor prodrug AHU377 (1:1 ratio). Oral administration of LCZ696 caused dose-dependent increases in atrial natriuretic peptide immunoreactivity (due to NEP inhibition) in Sprague-Dawley rats and provided sustained, dose-dependent blood pressure reductions in hypertensive double-transgenic rats. In healthy participants, a randomized, double-blind, placebo-controlled study (n = 80) of single-dose (200-1200 mg) and multiple-dose (50-900 mg once daily for 14 days) oral administration of LCZ696 showed that peak plasma concentrations were reached rapidly for valsartan (1.6-4.9 hours), AHU377 (0.5-1.1 hours), and its active moiety, LBQ657 (1.8-3.5 hours). LCZ696 is superior to valsartan alone in reducing blood pressure. Preliminary results from a Phase II trial showed that LCZ696 reduced NT-proBNP to a greater extent than valsartan alone, and in addition LCZ696 had beneficial effects on symptoms. Synonyms: calcium 4-(((2S,4R)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoate; AHU337; AHU-337; AHU 337; LCZ696; LCZ 696; LCZ696; Sacubitril. Grade: >98%. CAS No. 1369773-39-6. Molecular formula: C24H28NO5-. Mole weight: 410.48.
a-Hydroxyisobutyric acid 98+% (GC)
a-Hydroxyisobutyric acid 98+% (GC). Group: Biochemicals. Grades: GC. Pack Sizes: 25g, 100g, 250g, 1Kg, 5Kg. US Biological Life Sciences.
A metabolite of the chemotherapeutic drug tamoxifen. Exhibits a more potent estrogen agonist/antagonist activity than the parent drug. Also active as an intramembranous inhibitor of lipid peroxidation. Group: Biochemicals. Alternative Names: trans- (Z) -1-[4-[2- (Dimethylamino) ethoxy]phenyl]-1, 2-diphenyl-1-butene-3-ol. Grades: Highly Purified. CAS No. 97151-02-5Mol. Formula: »C26H29 NO2MoreDetails»Order». Pack Sizes: 10mg. US Biological Life Sciences.
AI-10-104 is an inhibitor for runt-related transcription factor (RUNX), which enhances the cytotoxicity in myeloma cells[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1881276-00-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122657.
AI-10-49
AI-10-49 is an inhibitor of leukemic oncoprotein CBF?-SMHHC. AI-10-49 inhibits the binding of CBF?-SMMHCto the RUNX1 Runt domain with IC50 value of 0.26 ?M. AI-10-49 can be used for the research of leukemia[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1256094-72-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16786.
AI-10-49
AI-10-49 is a protein-protein interaction inhibitor that selectively binds to CBFβ-SMMHC and disrupts its binding to RUNX1 with a FRET IC50 of 0.26 uM. Synonyms: AI-10-49; AI 10-49; AI10-49; AI-1049; AI 1049; AI1049. Grade: >98%. CAS No. 1256094-72-0. Molecular formula: C30H22F6N6O5. Mole weight: 660.52.
AI-3
AI-3 is an antioxidant response element activator and could probably be useful in studies of oxidative stress related diseases. Synonyms: AI-3; AI 3; AI3; 1-Chloro-6,7-dihydro-6,6-dimethyl-3-(methylsulfonyl)-benzo[c]thiophen-4(5H)-one. Grade: ≥98% by HPLC. CAS No. 882288-28-0. Molecular formula: C11H13ClO3S2. Mole weight: 292.80.
AI-3
AI-3. Group: Biochemicals. Grades: Purified. CAS No. 882288-28-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Aiap
Aiap. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (S)-(+)-AMINO-5-IODOACETAMIDOPENTANOIC ACID;(2S)-(+)-AMINO-5-IODOACETAMIDOPENTANOIC ACID;AIAP;(+)-s-2-amino-6-iodoacetamidohexanoicacid;2-aiha;2-amino-5-iodoacetamidopentanoicacid;n(sup5)-(iodoacetyl)-l-ornithin;n(sup5)-(iodoacetyl)-l-ornithine. Product Category: Heterocyclic Organic Compound. Appearance: White solid. CAS No. 35748-65-3. Molecular formula: C7H13IN2O3. Mole weight: 300.09. Purity: 0.96. IUPACName: (2S)-2-amino-5-[(2-iodoacetyl)amino]pentanoic acid. Density: 1.791g/cm³. Product ID: ACM35748653. Alfa Chemistry ISO 9001:2015 Certified. Categories: Aiapæc.
Aib18, Exendin-4
Exendin-4 (Exenatide), an agonist of glucagon-like peptide 1 (GLP-1) receptor, induces release of insulin after food intake. Synonyms: His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Aib-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2. Molecular formula: C189H291N51O61S. Mole weight: 4285.97.
Exendin-4 (Exenatide), an agonist of glucagon-like peptide 1 (GLP-1) receptor, induces release of insulin after food intake. Synonyms: His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2. Molecular formula: C186H286N50O60S. Mole weight: 4214.89.
Aibellin
It is produced by the strain of Vertocimonos poriurn ellipticum D1528. Alberin can enhance ruminant stomach fermentation, increase propionate production and reduce methane production caused by microorganisms in the stomach. Synonyms: AlamethicinI,2-L-alanine-9-L-phenylalanine-12-(2-methylalanine)-19-[N-[1-[[(2-hydroxyethyl)amino]methyl]-2-phenylethyl]-L-a-glutamine]-; L-a-Glutamine,N-acetyl-2-methylalanyl-L-alanyl-2-methylalanyl-L-alanyl-2-methylalanyl-L-alanyl-L-glutaminyl-2-methylalanyl-L-phenylalanyl-2-methylalanylglycyl-2-methylalanyl-2-methylalanyl-L-prolyl-L-valyl-2-methylalanyl-2-methylalanyl-L-a-glutamyl-N-[1-[[(2-hydroxyethyl)amino]methyl]-2-phenylethyl]-,(S)-. CAS No. 151036-29-2. Molecular formula: C94H147N21O27. Mole weight: 2003.29.
AICAR
AICAR (Acadesine) is an adenosine analog and a AMPK activator. AICAR regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR is also an autophagy , YAP and mitophagy inhibitor [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Acadesine; AICA Riboside. CAS No. 2627-69-2. Pack Sizes: 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13417.
AICAR
Cell permeable AMP-activated protein kinase (AMPK) activator. Insulin mimetic. Adipocyte differentiation inhibitor. Apoptosis inducer. PPARalpha inhibitor. mTOR inhibitor. P70S6K inhibitor. LPS-induced TNFalpha production inhibitor. TORC2 phosphorylation inducer. Anti-inflammatory. Anti-tumor compound. Autophagy inhibitor. HSP90 inhibitor. Group: Biochemicals. Alternative Names: 5-Aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside. Grades: Highly Purified. CAS No. 2627-69-2. Pack Sizes: 10mg, 50mg, 100mg. Molecular Formula: C9H14N4O5. US Biological Life Sciences.
Worldwide
AICAR 3',5'-cyclic phosphate
AICAR 3',5'-cyclic phosphate. Group: Biochemicals. Alternative Names: 5-Aminoimidazole-4-carboxamide-1-b-D-ribofuranosyl 3':5'-cyclic-monophosphate; 5-Amino-1-(3,5-O-phosphinico-b-D-ribofuranosyl)-1H-imidazole-4-carboxamide; NSC 371796. Grades: Highly Purified. CAS No. 35908-14-6. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C9H13N4O7P. US Biological Life Sciences.
Worldwide
AICAR 3',5'-Cyclic Phosphate
A cyclic nucleotide with protein kinase and phosphodiesterase activity. Synonyms: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 3':5'-cyclic-monophosphate; 5-Amino-1-(3,5-O-phosphinico-β-D-ribofuranosyl)-1H-imidazole-4-carboxamide; NSC 371796. Grade: 94%. CAS No. 35908-14-6. Molecular formula: C9H13N4O7P. Mole weight: 320.2.
AICAR 3,5-Cyclic Phosphate
A cyclic nucleotides with protein kinase and phosphodiesterase activity. Group: Biochemicals. Alternative Names: 5-Aminoimidazole-4-carboxamide-1- β-D-ribofuranosyl 3:5-cyclic-monophosphate;5-Amino-1-(3,5-O-phosphinico- β-D-ribofuranosyl)-1H-imidazole-4-carboxamide; NSC 371796. Grades: Highly Purified. CAS No. 35908-14-6. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
AICAR-5'-MP / ZMP
AICAR-5'-MP is an analogue of AICA-riboside, an alternative of 5'-AMP. AICAR-5'-MP is a purine precursor with antineoplastic activity and can be used in the study of type 2 diabetes. It can activate AMP-activated protein kinase. Synonyms: 1H-Imidazole-4-carboxamide, 5-amino-1-(5-O-phosphono-β-D-ribofuranosyl)-; 5-Amino-1-(5-O-phosphono-β-D-ribofuranosyl)-1H-imidazole-4-carboxamide; Imidazole-4-carboxamide, 5-amino-1-β-D-ribofuranosyl-, 5'-(dihydrogen phosphate); Imidazole-4-carboxamide, 5-amino-1-β-D-ribofuranosyl-, 5'-phosphate; 5-Amino-1-(5'-phosphofuranoribosyl)-4-imidazolecarboxamide; 5-Amino-1β-D-ribofuranosylimidazole-4-carboxamide 5'-phosphate; 5-Amino-4-imidazolecarboxamide ribonucleoside 5'-monophosphate; 5-Amino-4-imidazolecarboxamide ribonucleotide; 5-Amino-4-imidazolecarboxamide riboside 5'-monophosphate; 5-Amino-4-imidazolecarboxamide ribotide; 5-Aminoimidazole-4-carboxamide ribonucleotide; 5'-Phospho-β-D-ribosyl-5-amino-4-imidazolecarboxamide; 5'-Phosphoribosyl-5-amino-4-imidazolecarboxamide; Acadesine 5'-monophosphate; AICA Ribotide; AICA-Ribonucleotide; AICAR; AICAR monophosphate; AICAR (5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 5'-monophosphate); Aminoimidazolecarboxamide ribonucleotide; NSC 283955; NSC 292227; ZMP; ZMP (alarmone). Grade: ≥95%. CAS No. 3031-94-5. Molecular formula: C9H15N4O8P. Mole weight: 338.21.
AICA-Riboside, 5?-Phosphate - CAS 3031-94-5
A 5'-phosphorylated analog of membrane permeable AICA-Riboside that mimics AMP and acts as an activator of AMPK (AMP-activated protein kinase). Group: Fluorescence/luminescence spectroscopy.
AICAR phosphate
AICAR phosphate, is an AMP-activated protein kinase activator, which is used for the treatment of acute lymphoblastic leukemia and may have applications in treating other disorders such as diabetes. It stimulates glucose uptake and increases the activity of p38 mitogen-activated protein kinases α and β in skeletal muscle tissue, as well as suppressing apoptosis by reducing production of reactive oxygen compounds inside the cell. Synonyms: Acadesine phosphate; AICA Riboside phosphate. Grade: >98%. CAS No. 681006-28-0. Molecular formula: C9H17N4O9P. Mole weight: 356.23.
AICAR phosphate
AICAR phosphate (Acadesine phosphate) is an adenosine analog and a AMPK activator. AICAR phosphate regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR phosphate is also an autophagy , YAP and mitophagy inhibitor [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Acadesine phosphate; AICA Riboside phosphate. CAS No. 681006-28-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13417A.
AIDA
AIDA. Group: Biochemicals. Grades: Purified. CAS No. 168560-79-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
AIDA
AIDA is a selective group I mGluR agonist and could show centrally active following systemic administration in vivo. Uses: Excitatory amino acid antagonists. Synonyms: (RS)-1-Aminoindan-1,5-dicarboxylic acid. Grade: ≥98% by HPLC. CAS No. 168560-79-0. Molecular formula: C11H11NO4. Mole weight: 221.21.
A relatively potent and selective antagonist for group I mGlu receptor subtype 1 (pKB = 3.4 for mGlu1a). Complete absence of interacting with on group II or III mGluRs, or ionotropic glutamate receptors. Widely used in studying neural plasticity, learning and memory, and fear conditioning. Centrally active following systemic administration in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 168560-79-0. Pack Sizes: 5mg. Molecular Formula: C??H??NO?. US Biological Life Sciences.
Ailanthone (Δ13-Dehydrochaparrinone) is a potent inhibitor of both full-length androgen receptor (AR) ( IC 50 =69?nM) and constitutively active truncated AR splice variants (AR 1-651 IC 50 =309?nM). Uses: Scientific research. Group: Natural products. Alternative Names: Δ13-Dehydrochaparrinone. CAS No. 981-15-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1943.
Ailanthone
Botanical Source: Group: Biochemicals. Grades: Plant Grade. CAS No. 981-15-7. Pack Sizes: 10mg. US Biological Life Sciences.
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AIM 100
AIM 100. Group: Biochemicals. Grades: Purified. CAS No. 873305-35-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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AIM-100
AIM-100 is a small molecule inhibitor of Ack1. It not only inhibited Ack1 activation but also suppressed AKT tyrosine phosphorylation, leading to cell cycle arrest in the G1 phase. It could suppress AR Tyr(267) phosphorylation and its recruitment to the ATM enhancer and suppress pTyr267-AR phosphorylation, binding of AR to PSA, NKX3.1, and TMPRSS2 promoters, and inhibit AR transcription activity. Synonyms: AIM-100; AIM 100; AIM100. Grade: >98%. CAS No. 873305-35-2. Molecular formula: C23H21N3O2. Mole weight: 371.43.
AIM-100
AIM-100 is a potent and selective Ack1 tyrosine kinase with IC50 value of 24 nM. AIM-100, not only inhibited Ack1 activation but also able to suppress pTyr267-AR phosphorylation, binding of AR to PSA, NKX3.1, and TMPRSS2 promoters, and inhibit AR transcription activity. Ack1 tyrosine kinase activation correlates with pancreatic cancer progression. Ack1 inhibitors hold promise for therapeutic intervention to inhibit pancreatic tumor growth. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AIM-100; AIM 100; AIM100. Product Category: Others. Appearance: Solid powder. CAS No. 873305-35-2. Molecular formula: C23H21N3O2. Mole weight: 371.44. Purity: >98%. IUPACName: N-[[(2S)-oxolan-2-yl]methyl]-5,6-diphenylfuro[2,3-d]pyrimidin-4-amine. Canonical SMILES: C12=NC=NC(NC[C@H]3OCCC3)=C1C(C4=CC=CC=C4)=C(C5=CC=CC=C5)O2. Product ID: ACM873305352. Alfa Chemistry ISO 9001:2015 Certified.
a-Ionone
a-Ionone. Group: Biochemicals. Alternative Names: (3E)-4-(2,6,6-Trimethyl-2-cyclohexen-1-yl)3-buten-2-one; (5E)-Ionone; (E)-4-(2,6,6-Trimethyl-2-cyclohexen-1-yl)-3-buten-2-one. Grades: Highly Purified. CAS No. 127-41-3. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C13H20O. US Biological Life Sciences.
Worldwide
AITRL human
recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
AJ2-30
AJ2-30 is a SLCl5A4 inhibitor. AJ2-30 inhibits endolysosomal TLR7-9-mediated mTOR activation. AJ2-30 blocks endogenous NOD signaling. AJ2-30 can be used in inflammation studies[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2700322-79-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-155864.
AJI-9561
AJI-9561 is a benzoxazole derivative produced by Streptomyces sp. AJ9561. It has cytotoxic activity with IC50 of 0.88 μmol/L and 1.63 μmol/L for Jorkat and P388 cells, respectively. Its mechanism of action is the same as that of UK-1, which can inhibit DNA topoisomerase U. Synonyms: (2,4'-Bibenzoxazole)-4-carboxylic acid, 2'-(2-hydroxy-6-methylphenyl)-. CAS No. 339300-34-4. Molecular formula: C22H14N2O5. Mole weight: 386.36.
Ajmalicine
Ajmalicine (Raubasine) is a potent adrenolytic agent which preferentially blocks α 1 -adrenoceptor. Ajmalicine is an reversible but non-competitive nicotine receptor full inhibitor, with an IC 50 of 72.3 μM. Ajmalicine also can be used as anti-hypertensive, and serpentine, with sedative activity [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Raubasine. CAS No. 483-04-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N1919.
An antiarrhythmic agent isolated from Rauwolfia serpentina. Group: Biochemicals. Alternative Names: (17R,21α-Ajmalan-17,21-diol; (+)-Ajmaline; Cardiorythmine; Gilurytmal; Ignazin; Merabitol; NSC 15627; Raugalline; Rauwolfin; Rauwolfine; Rhytmaton; Ritmos; Rytmalin; Siddiqui; Tachmalin; Takycor. Grades: Highly Purified. CAS No. 4360-12-7. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Ajmaline
Ajmaline (Cardiorythmine) is a sodium channel blocking, class 1A anti-arrhythmic agent. Ajmaline blocks HERG currents with an IC 50 of 1 μM in HEK cells and 42.3 μM in Xenopus oocytes. Ajmaline can be used for the research of the ventricular tachyarrhythmia [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Cardiorythmine; (+)-Ajmaline. CAS No. 4360-12-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1167.
Ajn I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 55°C in a total reaction volume of 50 μl. Applications: 10 mm tris-hcl (ph 7.5); 100 mm nacl; 0.1 mm edta; 7 mm 2-mercaptoethanol; 200 μg/ml bsa; 50% glycerol. Group: Restriction Enzymes. Purity: 200U; 1000U. ↑CCWGG GGWCC&darr. Activity: 500-3000u.a./ml. Appearance: 10 X SE-buffer Y, BSA. Storage: -20°C. Form: Liquid. Source: Acinetobacter johnsonii R2. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: RE-1017EN.
Ajoene
Ajoene is a disulfide that has been found in A. sativum and has antitumor and antiplatelet activities. Ajoene inhibits proliferation and induces apoptosis of human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-I. Uses: Antiviral agents. Synonyms: (E)-Ajoene; 2-Propenyl-3-(2-propenylsulfinyl)-1-propenyl disulfide. CAS No. 92285-01-3. Molecular formula: C9H14OS3. Mole weight: 234.4.
Ajoene
Ajoene, a garlic-derived compound, is an antithrombotic and antifungal agent. Ajoene inhibits proliferation and induces apoptosis of human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-I. Anticancer activities [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 92285-01-3. Pack Sizes: 1 mg (21.33 mM * 200 μL in Ethyl acetate). Product ID: HY-106784.
Ajugasterone C
Ajugasterone C. Group: Biochemicals. Grades: Plant Grade. CAS No. 23044-80-6. Pack Sizes: 10mg. Molecular Formula: C27H44O7, Molecular Weight: 480.63. US Biological Life Sciences.
Worldwide
Ajuga Turkestancia P.E. 10% Turkesterone HPLC
Ajuga Turkestancia P.E. 10% Turkesterone HPLC.
CA, FL & NJ
Ajugol (Leonuride )
Ajugol (Leonuride ). Group: Biochemicals. Alternative Names: Ajugol; Leonuride. Grades: Plant Grade. CAS No. 52949-83-4. Pack Sizes: 20mg. Molecular Formula: C15H24O9, Molecular Weight: 348.346. US Biological Life Sciences.
Worldwide
AK-1
AK-1 is a potent, specific and cell-permeable SIRT2 inhibitor (IC50 = 12.5 μM) with excellent selectivity against SIRT1 and SIRT3 (IC50 >50 μM, and >50 μM for SIRT1 and SIRT3 respectively). Synonyms: AK-1; AK 1; AK1; DA-42784; KB-120200; Y1899; J-018989; DA42784; KB120200; J018989; DA 42784; KB 120200; J 018989; 3-(azepan-1-ylsulfonyl)-N-(3-nitrophenyl)benzamide; SIRT2 Inhibitor II, AK-1; SIRT2 Inhibitor II; CHEMBL1797749; 3-(azepan-1-ylsulfonyl)-N-(3-nitrophenyl)benzamide. CAS No. 330461-64-8. Molecular formula: C19H21N3O5S. Mole weight: 403.45.
AK-1 is a potent, specific and cell-permeable SIRT2 inhibitor, with an IC 50 of 12.5 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 330461-64-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101465.
AK-1690
AK-1690 is a potent and selective STAT6 PROTAC degrader. AK-1690 reduces the levels of STAT6 protein in cells (DC50=1 nM) and depletes STAT6 protein in mouse tissues. AK-1690 can be used for the research of cancer. (Pink: ligand for target protein STAT6 (HY-169182); Black: linker (HY-W459522); Blue: ligand for E3 ligase (HY-131318)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2984505-88-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-169179.