A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
AI-10-104 is an inhibitor for runt-related transcription factor (RUNX), which enhances the cytotoxicity in myeloma cells[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1881276-00-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122657.
AI-10-49
AI-10-49 is an inhibitor of leukemic oncoprotein CBF?-SMHHC. AI-10-49 inhibits the binding of CBF?-SMMHCto the RUNX1 Runt domain with IC50 value of 0.26 ?M. AI-10-49 can be used for the research of leukemia[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1256094-72-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16786.
AI-10-49
AI-10-49 is a protein-protein interaction inhibitor that selectively binds to CBFβ-SMMHC and disrupts its binding to RUNX1 with a FRET IC50 of 0.26 uM. Synonyms: AI-10-49; AI 10-49; AI10-49; AI-1049; AI 1049; AI1049. Grade: >98%. CAS No. 1256094-72-0. Molecular formula: C30H22F6N6O5. Mole weight: 660.52.
AI-3
AI-3 is an antioxidant response element activator and could probably be useful in studies of oxidative stress related diseases. Synonyms: AI-3; AI 3; AI3; 1-Chloro-6,7-dihydro-6,6-dimethyl-3-(methylsulfonyl)-benzo[c]thiophen-4(5H)-one. Grade: ≥98% by HPLC. CAS No. 882288-28-0. Molecular formula: C11H13ClO3S2. Mole weight: 292.80.
AI-3
AI-3. Group: Biochemicals. Grades: Purified. CAS No. 882288-28-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Aiap
Aiap. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (S)-(+)-AMINO-5-IODOACETAMIDOPENTANOIC ACID;(2S)-(+)-AMINO-5-IODOACETAMIDOPENTANOIC ACID;AIAP;(+)-s-2-amino-6-iodoacetamidohexanoicacid;2-aiha;2-amino-5-iodoacetamidopentanoicacid;n(sup5)-(iodoacetyl)-l-ornithin;n(sup5)-(iodoacetyl)-l-ornithine. Product Category: Heterocyclic Organic Compound. Appearance: White solid. CAS No. 35748-65-3. Molecular formula: C7H13IN2O3. Mole weight: 300.09. Purity: 0.96. IUPACName: (2S)-2-amino-5-[(2-iodoacetyl)amino]pentanoic acid. Density: 1.791g/cm³. Product ID: ACM35748653. Alfa Chemistry ISO 9001:2015 Certified. Categories: Aiapæc.
Aib18, Exendin-4
Exendin-4 (Exenatide), an agonist of glucagon-like peptide 1 (GLP-1) receptor, induces release of insulin after food intake. Synonyms: His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Aib-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2. Molecular formula: C189H291N51O61S. Mole weight: 4285.97.
Exendin-4 (Exenatide), an agonist of glucagon-like peptide 1 (GLP-1) receptor, induces release of insulin after food intake. Synonyms: His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2. Molecular formula: C186H286N50O60S. Mole weight: 4214.89.
Aibellin
It is produced by the strain of Vertocimonos poriurn ellipticum D1528. Alberin can enhance ruminant stomach fermentation, increase propionate production and reduce methane production caused by microorganisms in the stomach. Synonyms: AlamethicinI,2-L-alanine-9-L-phenylalanine-12-(2-methylalanine)-19-[N-[1-[[(2-hydroxyethyl)amino]methyl]-2-phenylethyl]-L-a-glutamine]-; L-a-Glutamine,N-acetyl-2-methylalanyl-L-alanyl-2-methylalanyl-L-alanyl-2-methylalanyl-L-alanyl-L-glutaminyl-2-methylalanyl-L-phenylalanyl-2-methylalanylglycyl-2-methylalanyl-2-methylalanyl-L-prolyl-L-valyl-2-methylalanyl-2-methylalanyl-L-a-glutamyl-N-[1-[[(2-hydroxyethyl)amino]methyl]-2-phenylethyl]-,(S)-. CAS No. 151036-29-2. Molecular formula: C94H147N21O27. Mole weight: 2003.29.
AICAR
AICAR (Acadesine) is an adenosine analog and a AMPK activator. AICAR regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR is also an autophagy , YAP and mitophagy inhibitor [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Acadesine; AICA Riboside. CAS No. 2627-69-2. Pack Sizes: 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13417.
AICAR
Cell permeable AMP-activated protein kinase (AMPK) activator. Insulin mimetic. Adipocyte differentiation inhibitor. Apoptosis inducer. PPARalpha inhibitor. mTOR inhibitor. P70S6K inhibitor. LPS-induced TNFalpha production inhibitor. TORC2 phosphorylation inducer. Anti-inflammatory. Anti-tumor compound. Autophagy inhibitor. HSP90 inhibitor. Group: Biochemicals. Alternative Names: 5-Aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside. Grades: Highly Purified. CAS No. 2627-69-2. Pack Sizes: 10mg, 50mg, 100mg. Molecular Formula: C9H14N4O5. US Biological Life Sciences.
Worldwide
AICAR 3',5'-cyclic phosphate
AICAR 3',5'-cyclic phosphate. Group: Biochemicals. Alternative Names: 5-Aminoimidazole-4-carboxamide-1-b-D-ribofuranosyl 3':5'-cyclic-monophosphate; 5-Amino-1-(3,5-O-phosphinico-b-D-ribofuranosyl)-1H-imidazole-4-carboxamide; NSC 371796. Grades: Highly Purified. CAS No. 35908-14-6. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C9H13N4O7P. US Biological Life Sciences.
Worldwide
AICAR 3',5'-Cyclic Phosphate
A cyclic nucleotide with protein kinase and phosphodiesterase activity. Synonyms: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 3':5'-cyclic-monophosphate; 5-Amino-1-(3,5-O-phosphinico-β-D-ribofuranosyl)-1H-imidazole-4-carboxamide; NSC 371796. Grade: 94%. CAS No. 35908-14-6. Molecular formula: C9H13N4O7P. Mole weight: 320.2.
AICAR 3,5-Cyclic Phosphate
A cyclic nucleotides with protein kinase and phosphodiesterase activity. Group: Biochemicals. Alternative Names: 5-Aminoimidazole-4-carboxamide-1- β-D-ribofuranosyl 3:5-cyclic-monophosphate;5-Amino-1-(3,5-O-phosphinico- β-D-ribofuranosyl)-1H-imidazole-4-carboxamide; NSC 371796. Grades: Highly Purified. CAS No. 35908-14-6. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
AICAR-5'-MP / ZMP
AICAR-5'-MP is an analogue of AICA-riboside, an alternative of 5'-AMP. AICAR-5'-MP is a purine precursor with antineoplastic activity and can be used in the study of type 2 diabetes. It can activate AMP-activated protein kinase. Synonyms: 1H-Imidazole-4-carboxamide, 5-amino-1-(5-O-phosphono-β-D-ribofuranosyl)-; 5-Amino-1-(5-O-phosphono-β-D-ribofuranosyl)-1H-imidazole-4-carboxamide; Imidazole-4-carboxamide, 5-amino-1-β-D-ribofuranosyl-, 5'-(dihydrogen phosphate); Imidazole-4-carboxamide, 5-amino-1-β-D-ribofuranosyl-, 5'-phosphate; 5-Amino-1-(5'-phosphofuranoribosyl)-4-imidazolecarboxamide; 5-Amino-1β-D-ribofuranosylimidazole-4-carboxamide 5'-phosphate; 5-Amino-4-imidazolecarboxamide ribonucleoside 5'-monophosphate; 5-Amino-4-imidazolecarboxamide ribonucleotide; 5-Amino-4-imidazolecarboxamide riboside 5'-monophosphate; 5-Amino-4-imidazolecarboxamide ribotide; 5-Aminoimidazole-4-carboxamide ribonucleotide; 5'-Phospho-β-D-ribosyl-5-amino-4-imidazolecarboxamide; 5'-Phosphoribosyl-5-amino-4-imidazolecarboxamide; Acadesine 5'-monophosphate; AICA Ribotide; AICA-Ribonucleotide; AICAR; AICAR monophosphate; AICAR (5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 5'-monophosphate); Aminoimidazolecarboxamide ribonucleotide; NSC 283955; NSC 292227; ZMP; ZMP (alarmone). Grade: ≥95%. CAS No. 3031-94-5. Molecular formula: C9H15N4O8P. Mole weight: 338.21.
AICA-Riboside, 5?-Phosphate - CAS 3031-94-5
A 5'-phosphorylated analog of membrane permeable AICA-Riboside that mimics AMP and acts as an activator of AMPK (AMP-activated protein kinase). Group: Fluorescence/luminescence spectroscopy.
AICAR phosphate
AICAR phosphate (Acadesine phosphate) is an adenosine analog and a AMPK activator. AICAR phosphate regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR phosphate is also an autophagy , YAP and mitophagy inhibitor [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Acadesine phosphate; AICA Riboside phosphate. CAS No. 681006-28-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13417A.
AICAR phosphate
AICAR phosphate, is an AMP-activated protein kinase activator, which is used for the treatment of acute lymphoblastic leukemia and may have applications in treating other disorders such as diabetes. It stimulates glucose uptake and increases the activity of p38 mitogen-activated protein kinases α and β in skeletal muscle tissue, as well as suppressing apoptosis by reducing production of reactive oxygen compounds inside the cell. Synonyms: Acadesine phosphate; AICA Riboside phosphate. Grade: >98%. CAS No. 681006-28-0. Molecular formula: C9H17N4O9P. Mole weight: 356.23.
AIDA
AIDA is a selective group I mGluR agonist and could show centrally active following systemic administration in vivo. Uses: Excitatory amino acid antagonists. Synonyms: (RS)-1-Aminoindan-1,5-dicarboxylic acid. Grade: ≥98% by HPLC. CAS No. 168560-79-0. Molecular formula: C11H11NO4. Mole weight: 221.21.
AIDA
AIDA. Group: Biochemicals. Grades: Purified. CAS No. 168560-79-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
A relatively potent and selective antagonist for group I mGlu receptor subtype 1 (pKB = 3.4 for mGlu1a). Complete absence of interacting with on group II or III mGluRs, or ionotropic glutamate receptors. Widely used in studying neural plasticity, learning and memory, and fear conditioning. Centrally active following systemic administration in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 168560-79-0. Pack Sizes: 5mg. Molecular Formula: C??H??NO?. US Biological Life Sciences.
Ailanthone (Δ13-Dehydrochaparrinone) is a potent inhibitor of both full-length androgen receptor (AR) ( IC 50 =69?nM) and constitutively active truncated AR splice variants (AR 1-651 IC 50 =309?nM). Uses: Scientific research. Group: Natural products. Alternative Names: Δ13-Dehydrochaparrinone. CAS No. 981-15-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1943.
Ailanthone
Botanical Source: Group: Biochemicals. Grades: Plant Grade. CAS No. 981-15-7. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
AIM 100
AIM 100. Group: Biochemicals. Grades: Purified. CAS No. 873305-35-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
AIM-100
AIM-100 is a small molecule inhibitor of Ack1. It not only inhibited Ack1 activation but also suppressed AKT tyrosine phosphorylation, leading to cell cycle arrest in the G1 phase. It could suppress AR Tyr(267) phosphorylation and its recruitment to the ATM enhancer and suppress pTyr267-AR phosphorylation, binding of AR to PSA, NKX3.1, and TMPRSS2 promoters, and inhibit AR transcription activity. Synonyms: AIM-100; AIM 100; AIM100. Grade: >98%. CAS No. 873305-35-2. Molecular formula: C23H21N3O2. Mole weight: 371.43.
AIM-100
AIM-100 is a potent and selective Ack1 tyrosine kinase with IC50 value of 24 nM. AIM-100, not only inhibited Ack1 activation but also able to suppress pTyr267-AR phosphorylation, binding of AR to PSA, NKX3.1, and TMPRSS2 promoters, and inhibit AR transcription activity. Ack1 tyrosine kinase activation correlates with pancreatic cancer progression. Ack1 inhibitors hold promise for therapeutic intervention to inhibit pancreatic tumor growth. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AIM-100; AIM 100; AIM100. Product Category: Others. Appearance: Solid powder. CAS No. 873305-35-2. Molecular formula: C23H21N3O2. Mole weight: 371.44. Purity: >98%. IUPACName: N-[[(2S)-oxolan-2-yl]methyl]-5,6-diphenylfuro[2,3-d]pyrimidin-4-amine. Canonical SMILES: C12=NC=NC(NC[C@H]3OCCC3)=C1C(C4=CC=CC=C4)=C(C5=CC=CC=C5)O2. Product ID: ACM873305352. Alfa Chemistry ISO 9001:2015 Certified.
a-Ionone
a-Ionone. Group: Biochemicals. Alternative Names: (3E)-4-(2,6,6-Trimethyl-2-cyclohexen-1-yl)3-buten-2-one; (5E)-Ionone; (E)-4-(2,6,6-Trimethyl-2-cyclohexen-1-yl)-3-buten-2-one. Grades: Highly Purified. CAS No. 127-41-3. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C13H20O. US Biological Life Sciences.
Worldwide
AITRL human
recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
AJ2-30
AJ2-30 is a SLCl5A4 inhibitor. AJ2-30 inhibits endolysosomal TLR7-9-mediated mTOR activation. AJ2-30 blocks endogenous NOD signaling. AJ2-30 can be used in inflammation studies[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2700322-79-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-155864.
AJI-9561
AJI-9561 is a benzoxazole derivative produced by Streptomyces sp. AJ9561. It has cytotoxic activity with IC50 of 0.88 μmol/L and 1.63 μmol/L for Jorkat and P388 cells, respectively. Its mechanism of action is the same as that of UK-1, which can inhibit DNA topoisomerase U. Synonyms: (2,4'-Bibenzoxazole)-4-carboxylic acid, 2'-(2-hydroxy-6-methylphenyl)-. CAS No. 339300-34-4. Molecular formula: C22H14N2O5. Mole weight: 386.36.
Ajmalicine (Raubasine) is a potent adrenolytic agent which preferentially blocks α 1 -adrenoceptor. Ajmalicine is an reversible but non-competitive nicotine receptor full inhibitor, with an IC 50 of 72.3 μM. Ajmalicine also can be used as anti-hypertensive, and serpentine, with sedative activity [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Raubasine. CAS No. 483-04-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N1919.
Ajmaline
Ajmaline (Cardiorythmine) is a sodium channel blocking, class 1A anti-arrhythmic agent. Ajmaline blocks HERG currents with an IC 50 of 1 μM in HEK cells and 42.3 μM in Xenopus oocytes. Ajmaline can be used for the research of the ventricular tachyarrhythmia [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Cardiorythmine; (+)-Ajmaline. CAS No. 4360-12-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1167.
Ajmaline
An antiarrhythmic agent isolated from Rauwolfia serpentina. Group: Biochemicals. Alternative Names: (17R,21α-Ajmalan-17,21-diol; (+)-Ajmaline; Cardiorythmine; Gilurytmal; Ignazin; Merabitol; NSC 15627; Raugalline; Rauwolfin; Rauwolfine; Rhytmaton; Ritmos; Rytmalin; Siddiqui; Tachmalin; Takycor. Grades: Highly Purified. CAS No. 4360-12-7. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Ajn I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 55°C in a total reaction volume of 50 μl. Applications: 10 mm tris-hcl (ph 7.5); 100 mm nacl; 0.1 mm edta; 7 mm 2-mercaptoethanol; 200 μg/ml bsa; 50% glycerol. Group: Restriction Enzymes. Purity: 200U; 1000U. ↑CCWGG GGWCC&darr. Activity: 500-3000u.a./ml. Appearance: 10 X SE-buffer Y, BSA. Storage: -20°C. Form: Liquid. Source: Acinetobacter johnsonii R2. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: RE-1017EN.
Ajoene
Ajoene, a garlic-derived compound, is an antithrombotic and antifungal agent. Ajoene inhibits proliferation and induces apoptosis of human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-I. Anticancer activities [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 92285-01-3. Pack Sizes: 1 mg (21.33 mM * 200 μL in Ethyl acetate). Product ID: HY-106784.
Ajoene
Ajoene is a disulfide that has been found in A. sativum and has antitumor and antiplatelet activities. Ajoene inhibits proliferation and induces apoptosis of human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-I. Uses: Antiviral agents. Synonyms: (E)-Ajoene; 2-Propenyl-3-(2-propenylsulfinyl)-1-propenyl disulfide. CAS No. 92285-01-3. Molecular formula: C9H14OS3. Mole weight: 234.4.
Ajugasterone C
Ajugasterone C. Group: Biochemicals. Grades: Plant Grade. CAS No. 23044-80-6. Pack Sizes: 10mg. Molecular Formula: C27H44O7, Molecular Weight: 480.63. US Biological Life Sciences.
Worldwide
Ajuga Turkestancia P.E. 10% Turkesterone HPLC
Ajuga Turkestancia P.E. 10% Turkesterone HPLC.
CA, FL & NJ
Ajugol (Leonuride )
Ajugol (Leonuride ). Group: Biochemicals. Alternative Names: Ajugol; Leonuride. Grades: Plant Grade. CAS No. 52949-83-4. Pack Sizes: 20mg. Molecular Formula: C15H24O9, Molecular Weight: 348.346. US Biological Life Sciences.
AK-1 is a potent, specific and cell-permeable SIRT2 inhibitor, with an IC 50 of 12.5 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 330461-64-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101465.
AK-1
AK-1 is a potent, specific and cell-permeable SIRT2 inhibitor (IC50 = 12.5 μM) with excellent selectivity against SIRT1 and SIRT3 (IC50 >50 μM, and >50 μM for SIRT1 and SIRT3 respectively). Synonyms: AK-1; AK 1; AK1; DA-42784; KB-120200; Y1899; J-018989; DA42784; KB120200; J018989; DA 42784; KB 120200; J 018989; 3-(azepan-1-ylsulfonyl)-N-(3-nitrophenyl)benzamide; SIRT2 Inhibitor II, AK-1; SIRT2 Inhibitor II; CHEMBL1797749; 3-(azepan-1-ylsulfonyl)-N-(3-nitrophenyl)benzamide. CAS No. 330461-64-8. Molecular formula: C19H21N3O5S. Mole weight: 403.45.
AK-1690
AK-1690 is a potent and selective STAT6 PROTAC degrader. AK-1690 reduces the levels of STAT6 protein in cells (DC50=1 nM) and depletes STAT6 protein in mouse tissues. AK-1690 can be used for the research of cancer. (Pink: ligand for target protein STAT6 (HY-169182); Black: linker (HY-W459522); Blue: ligand for E3 ligase (HY-131318)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2984505-88-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-169179.
AK-2292
AK-2292 is a potent and selective STAT5 PROTAC degrader, with a DC50 of 0.10 ?M. AK-2292 induces degradation of STAT5A/B proteins in vitro and in vivo. AK-2292 can induce tumor regression in acute myeloid leukemia and chronic myeloid leukemia xenograft mouse models[1][2]. AK-2292 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2984506-77-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148813.
AK 7
AK 7. Group: Biochemicals. Grades: Purified. CAS No. 420831-40-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
AK-7
Brain-permeable SIRT2 (sirtuin 2) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 420831-40-9. Pack Sizes: 5mg, 25mg. Molecular Formula: C19H21BrN2O3S. US Biological Life Sciences.
Worldwide
AK-7
AK-7 is a selective and brain-permeable SIRT2 inhibitor, which displays no effect on SIRT1 or SIRT3. It could decrease neuronal cholesterol levels and improve motor function and ameliorates brain atrophy in a mouse model of Huntington's disease. Synonyms: AK-7; CS-3223; GL-8955; AK7; CS3223; GL8955; AK 7; CS 3223; GL 8955. Grade: >98%. CAS No. 420831-40-9. Molecular formula: C19H21BrN2O3S. Mole weight: 437.35.
AK-7
AK-7 is a selective cell- and brain-permeable SIRT2 inhibitor, with an IC 50 of 15.5 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 420831-40-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16691.
AK-778-XXMU is a potent inhibitor of DNA Binding 2 (ID2) antagonist with a KD of 129 nM. AK-778-XXMU can inhibit cell migration and invasion of glioma cell lines, induce apoptosis, and more importantly, slow down the tumor growth[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1227045-76-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144707.
AK 7 (N-(3-Bromophenyl)-3-[(hexahydro-1H- azepin-1-yl)sulfonyl]benzamide)
Selective SIRT2 inhibitor (IC50 = 15.5um); displays no effect on SIRT1 or SIRT3. Decreases neuronal cholesterol levels; improves motor function and ameliorates brain atrophy in a mouse model of Huntington's disease. Brain penetrant. Group: Biochemicals. Grades: Highly Purified. CAS No. 420831-40-9. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
AkaLumine hydrochloride
AkaLumine hydrochloride is a D-luciferin (HY-12591A) analogue with a Km of 2.06 ?M for recombinant firefly luciferase (Fluc) protein. AkaLumine hydrochloride emits near-infrared (NIR) light (?max=677?nm) in reactions with native Fluc. AkaLumine hydrochloride has high tissue-penetration and increases detection sensitivity from deep-tissue targets[1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 2558205-28-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112641A.
Akardit II
Akardit II. Group: Biochemicals. Grades: Highly Purified. CAS No. 13114-72-2. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences.
Worldwide
Akarkara P.E. 10:1 (Anacyclus Pyrethrum)
Akarkara P.E. 10:1 (Anacyclus Pyrethrum).
CA, FL & NJ
AKB48-d11
AKB48-d11. Group: Biochemicals. Alternative Names: 1-Pentyl-N-tricyclo[3.3.1.13, 7]dec-1-yl-1H-indazole-3-carboxamide-d11. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C23H20D11N3O, Molecular Weight: 376.58. US Biological Life Sciences.
Worldwide
AKB48 N-Pentanoic Acid
AKB48 N-Pentanoic Acid. Group: Biochemicals. Alternative Names: APINACA N-Pentanoic Acid; 5-(3-((3s,5s,7s)-Adamantan-1-ylcarbamoyl)-1H-indazol-1-yl)pentanoic Acid. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C23H29N3O3, Molecular Weight: 395.49. US Biological Life Sciences.
Worldwide
AKBA
AKBA (Acetyl-11-keto-β-boswellic acid) is an active triterpenoid compound from the extract of Boswellia serrate and a novel Nrf2 activator. Uses: Scientific research. Group: Natural products. Alternative Names: Acetyl-11-keto-β-boswellic acid. CAS No. 67416-61-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N0892.
AKBA (Standard)
AKBA (Standard) is the analytical standard of AKBA. This product is intended for research and analytical applications. AKBA (Acetyl-11-keto-β-boswellic acid) is an active triterpenoid compound from the extract of Boswellia serrate and a novel Nrf2 activator. Uses: Scientific research. Group: Natural products. CAS No. 67416-61-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0892R.
a-Ketobutyric acid sodium salt 99+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 2013-26-5. Pack Sizes: 5g, 25g, 100g. US Biological Life Sciences.
Worldwide
a-Ketoglutaric acid disodium salt
a-Ketoglutaric acid disodium salt. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100g, 250g, 25g, 1Kg, 5Kg. US Biological Life Sciences.
Worldwide
a-Ketoglutaric Acid Disodium Salt Dihydrate
a-Ketoglutaric Acid Disodium Salt Dihydrate. Group: Biochemicals. Alternative Names: 2-Oxoglutaric acid disodium salt; Disodium 2-ketoglutarate. Grades: Highly Purified. CAS No. 305-72-6. Pack Sizes: 50g, 100g, 250g, 500g, 1Kg. Molecular Formula: C5H4Na2O5·2H2O, Molecular Weight: 226.09. US Biological Life Sciences.
Worldwide
a-Ketoglutaric acid disodium salt dihydrate 99+%
a-Ketoglutaric acid disodium salt dihydrate 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 25g, 100g, 250g, 1Kg, 5Kg. US Biological Life Sciences.
Worldwide
a-Ketoglutaric acid potassium salt
a-Ketoglutaric acid potassium salt. Group: Biochemicals. Alternative Names: 2-Oxopentanedioic acid potassium salt; Potassium hydrogen 2-ketoglutarate. Grades: Highly Purified. CAS No. 997-43-3. Pack Sizes: 25g, 50g, 100g. Molecular Formula: C?H?O?K, Molecular Weight: 184.19. US Biological Life Sciences.
Worldwide
AKI-001
AKI-001 is a potent Aurora kinase inhibitor, which exhibits low nanomolar potency against both Aurora A and Aurora B enzymes, excellent cellular potency (IC50 < 100 nM), and good oral bioavailability. Synonyms: AKI-001; AKI 001; AKI001. Grade:>98%. CAS No. 925218-37-7. Molecular formula: C21H24N4O. Mole weight: 348.45.
AKI603
AKI603 is an inhibitor of Aurora kinase A (AurA) with IC50 of 12.3 nM. It can induce senescence in chronic myeloid leukemia cells carrying the T315I mutation. AKI603 shows strong anti-proliferative activity in leukemia cells. Synonyms: AKI-603. Grade: 98%. CAS No. 1432515-73-5. Molecular formula: C19H23N9O2. Mole weight: 409.4.