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| Product | Description | |
|---|---|---|
| Akos bc-1945 | Akos bc-1945. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS BC-1945;CHEMBRDG-BB 9071388;3-(3,4-DIMETHYLPHENOXY)-N-METHYL-1-PROPANAMINE;UKRORGSYN-BB BBV-182444. Product Category: Heterocyclic Organic Compound. CAS No. 915923-36-3. Molecular formula: C12H19NO. Mole weight: 193.288. Product ID: ACM915923363. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Akos bc-1949 | Akos bc-1949. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS BC-1949;CHEMBRDG-BB 9070580;N-METHYL-3-(4-METHYLPHENOXY)-1-PROPANAMINE;UKRORGSYN-BB BBV-253231. Product Category: Heterocyclic Organic Compound. CAS No. 915923-08-9. Molecular formula: C11H17NO. Mole weight: 179.261. Product ID: ACM915923089. Alfa Chemistry ISO 9001:2015 Certified. | |
| Akos bc-3058 | Akos bc-3058. Uses: Designed for use in research and industrial production. Additional or Alternative Names: IFLAB-BB F0898-0214;AKOS BC-3058;N-[1-AMINO-1-PHENYL-METH-(Z)-YLIDENE]-BENZENESULFONAMIDE. Product Category: Heterocyclic Organic Compound. CAS No. 14067-77-7. Molecular formula: C13H12N2O2S. Mole weight: 260.31. Product ID: ACM14067777. Alfa Chemistry ISO 9001:2015 Certified. | |
| Akos pao-0857 | Akos pao-0857. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS PAO-0857;CHEMBRDG-BB 4002917;3-(1-METHYL-1H-PYRAZOL-4-YL)PROPAN-1-OL. Product Category: Heterocyclic Organic Compound. CAS No. 192661-38-4. Molecular formula: C7H12N2O. Mole weight: 140.18. Product ID: ACM192661384. Alfa Chemistry ISO 9001:2015 Certified. | |
| Akos pao-1153 | Akos pao-1153. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS PAO-1153;3-Isobutyl-1H-pyrazole. Product Category: Heterocyclic Organic Compound. CAS No. 98816-40-1. Molecular formula: C7H12N2. Product ID: ACM98816401. Alfa Chemistry ISO 9001:2015 Certified. | |
| AKR1C1-IN-1 | AKR1C1-IN-1 is a potent and selective inhibitor of human 20?-hydroxysteroid dehydrogenase (AKR1C1), with a Ki value of 4 nM for AKR1C1[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4906-68-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114009. |  |
| AKR1C1 Inhibitor, 5-PBSA | A cell-permeable salicylic acid compound that acts as a highly potent, active-site directed and substrate competitive AKR1C1 inhibitor (Ki=4nM) with moderate to excellent selectivity over AKR1C2, AKR1C3 and AKR1C4 (Ki=0.087, 4.2 and 18.2uM, respectively). Shown to inhibit the metabolism of progesterone by AKR1C1 (IC50=460nM in AKR1C1 overexpressing BAECs).CAS No.4906-68-7. Group: Biochemicals. Alternative Names: Aldo-Keto Reductase family 1 member C1 Inhibitor, 5-PBSA, 3-Bromo-5-phenylsalicylic acid, 20α-Hydroxysteroid Dehydrogenase Inhibitor, 5-PBSA. Grades: Highly Purified. CAS No. 4906-68-7. Pack Sizes: 25mg. Molecular Formula: C??H?BrO?. US Biological Life Sciences. |  Worldwide |
| AKR1C3 Inhibitor (3- (4- (Trifluoromethyl) phenylamino) benzoic Acid) | A cell-permeable 3-phenyl-aminobenzoate compound that acts as a potent, competitive, reversible, active-site targeting inhibitor of aldo-keto reductase 1C3 (AKR1C3; type 5 17b-hydroxysteroid dehydrogenase) (IC50 = 60nM) with excellent selectivity over other closely related human AKR isoforms (IC50 = 22.7, 15.4, 62.7, >50, and >50uM for and AKR1C1, AKR1C2, AKR1C4, AKR1B1 and AKR1B10, respectively. Exhibits a weak inhibitory effect on cyclooxygenase 1 and 2 (IC50 = 100uM). Shown to efficiently block the AKR1C3-mediated production of testosterone in LNCaP-AKR1C3 cells (~10uM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Akrobomycin | It is produced by the strain of Actinomadura reseoviolacea 129-AVI. It has anti-gram-negative bacteria, ringworm and tumor activity. Synonyms: 9,10-Anhydro-13-deoxocarminomycin; 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-8-ethyl-9,10-dihydro-1,6,11-trihydroxy-, (S)-; DTXSID601008673; LS-94000; 3-Ethyl-5,10,12-trihydroxy-6,11-dioxo-1,2,6,11-tetrahydrotetracen-1-yl 3-amino-2,3,6-trideoxyhexopyranoside; Akrobomycin; Rubomycin Q1. CAS No. 89156-94-5. Molecular formula: C26H27NO8. Mole weight: 481.49. |  |
| Akt1/2 kinase inhibitor | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| AKT1, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Akt1 active human | recombinant, expressed in baculovirus infected Sf9 cells, ?75% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| Akt1 and Akt2-IN-1 | Akt1 and Akt2-IN-1 is an allosteric inhibitor of Akt1 and Akt2 with the IC50 of 3.5 nM and 42 nM respectively. It has potent and balanced activity. It is dependent on the PH-domain for Akt inhibition. It is selective for Akt1/2 over Akt3 and is highly selective over other members of the AGC family of kinases in vitro. It has potent inhibitory activity against Akt1 and Akt 2 in vivo in a mouse lung and efficacy in a tumor xenograft model. It has moderate activity in an hERG binding assay and is a substrate for human P-glycoprotein. It also shows good physical properties with a human plasma protein binding. Uses: Akt1 and akt2-in-1 has potent inhibitory activity against akt1 and akt 2 and efficacy in a tumor xenograft model. Synonyms: Akt Inhibitor 17; Akti_2008; Akti 2008; Akti2008; Akti-2008; Akt Inhibitor 17; Akt-Inhibitor-17; AktInhibitor17; 3-Phenyl-2-[4-[[4-[5-(2-pyridinyl)-1H-1,2,4-triazol-3-yl]-1-piperidinyl]methyl]phenyl]-1,6-Naphthyridin-5(6H)-one; Akti_2008; 3-phenyl-2-[4-[[4-(3-pyridin-2-yl-1H-1,2,4-triazol-5-yl)piperidin-1-yl]methyl]phenyl]-6H-1,6-naphthyridin-5-one. Grade: >98%. CAS No. 893422-47-4. Molecular formula: C33H29N7O. Mole weight: 539.63. | |
| AKT2, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| AKT2, active, His tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| AKT3, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Akt3 active human | recombinant, expressed in baculovirus infected Sf9 cells, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| Akt Activator II, SC79 (Ethyl-2-amino-6-chloro-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate) | A cell-permeable and blood-brain barrier permeant HA14-1 analog that interacts with Akt PH domain PtdIns(3,4,5)P3- (PIP3) binding pocket, rendering Akt in a conformation susceptible to phosphorylation by upstream kinases. Shown to enhance both basal and receptor-mediated Akt phosphorylation (Thr308 and Ser473; 2 to 4ug/ml) with concomitant inhibition Akt membrane translocation in various cell cultures. Efficiently reduces glutamate-induced neurotoxicity both in primary neuron cultures (EC50 = 4ug/ml) in vitro and in a murine MCAO model (40mg/kg, i.p.) in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 305834-79-1. Pack Sizes: 25mg. Molecular Formula: C??H??ClN?O?. US Biological Life Sciences. | Worldwide |
| Akt Control Cell Extracts (Rac PKa, PKBa) | Akt Control Cell Extracts (Rac PKa, PKBa). Group: Biologicals. Grades: Lysate. Pack Sizes: 10Blots. US Biological Life Sciences. | Worldwide |
| Akt, dephosphorylated Positive Control (Ser473) (Rac PKa, PKBa) | Positive control for A1124-02D. Group: Molecular Biology. Pack Sizes: 200ul. US Biological Life Sciences. | Worldwide |
| Akt-I-1 | AKT-I-1 is a selective and reversible inhibitor of Akt1. Synonyms: Akt-I-1 compound; AktI 1; N3-(7-Cyclobutyl-3-phenyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-N1,N1,2,2-tetramethyl-1,3-propanediamine. CAS No. 473382-39-7. Molecular formula: C22H30N6. Mole weight: 378.51. | |
| Akti-1/2 | Akti-1/2. Group: Biochemicals. Alternative Names: 1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]4-piperidinyl]-2H-benzimidazol-2-one. Grades: Highly Purified. CAS No. 612847-09-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C34H29N7O. US Biological Life Sciences. | Worldwide |
| Akti-1/2 (1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]guinoxalin-7-yl)phenyl]methyl]4-piperidinyl]-2H-benzimidazol-2-one) | Allosteric Akt (PKB) inhibitors used in synergistic combination therapy for the treatment of cancer. Group: Biochemicals. Alternative Names: 1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]guinoxalin-7-yl)phenyl]methyl]4-piperidinyl]-2H-benzimidazol-2-one. Grades: Highly Purified. CAS No. 612847-09-3. Pack Sizes: 2mg. US Biological Life Sciences. | Worldwide |
| Akt-I-1,2 HCl | Akt-I-1,2 is a selective, non-ATP-competitive Akt1 and Akt2 inhibitor. Synonyms: Akt I 1,2 HCl; AktI1,2 HCl; Benzenemethanamine, alpha,alpha-dimethyl-4-(3-phenyl-2-quinoxalinyl)-, hydrochloride (1:1). CAS No. 473382-50-2. Molecular formula: C23H22ClN3. Mole weight: 375.90. | |
| AKTide-2T | AKTide-2T. Group: Biochemicals. Grades: Purified. CAS No. 324029-01-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| AKTide-2T | AKTide-2T, a peptide substrate for Akt/PKB, has been found to act as an inhibitor and mimics the optimal phosphorylation sequence of Akt. Synonyms: AKTide-2T; 324029-01-8; ARKRERTYSFGHHA; AKOS024457090; PD079315. Grade: ≥95% by HPLC. CAS No. 324029-01-8. Molecular formula: C74H114N28O20. Mole weight: 1715.89. | |
| AKTide-2T TFA | AKTide-2T is a peptide substrate for Akt/PKB. It acts as an inhibitor and mimics the optimal phosphorylation sequence of Akt. Molecular formula: C76H115F3N28O22. Mole weight: 1829.89. | |
| AKT-IN-11 | AKT-IN-11 is one of the most effective antibacterial agents against human hepatoma BEL-7402 cell line with an IC50 of 1.15 μM. Synonyms: (7R)-5-chloro-3-((1E,3E)-3,5-dimethylhepta-1,3-dien-1-yl)-7-hydroxy-7-methyl-2-(4-(trifluoromethoxy)benzyl)isoquinoline-6,8(2H,7H)-dione. Molecular formula: C27H27ClF3NO4. Mole weight: 521.96. | |
| AKT-IN-2 | AKT-IN-2 is a selective and orally bioavailable AKT inhibitor (IC50 = 5 nM for AKT1). Synonyms: AKT-IN-2; CHEMBL4129379; SCHEMBL1662401; QRULDXBXPXGMQS-QGZVFWFLSA-N; QRULDXBXPXGMQS-QGZVFWFLSA-O; BDBM50271964; AKOS040732404; HY-112148; CS-0043488; (R)-5-methyl-4-(4-(1-(2-(pyrrolidin-1-yl)ethyl)-4-(3,3,3-trifluoropropyl)-1H-imidazol-2-yl)piperidin-1-yl)-5,6-dihydropyrido[2,3-d]pyrimidin-7(8H)-one; 1295514-91-8. CAS No. 1295514-91-8. Molecular formula: C25H34F3N7O. Mole weight: 505.58. | |
| AKT-IN-23 | AKT-IN-23 is an AKT inhibitor. AKT-IN-23 can be used in cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1226801-23-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-161704. | |
| AKT-IN-3 | AKT-IN-3 is a potent and orally active low hERG blocking Akt inhibitor, with 1.4 nM, 1.2 nM and 1.7 nM for Akt1, Akt2 and Akt3, respectively. AKT-IN-3 also shows good inhibitory activity against other AGC family kinases, such as PKA, PKC, ROCK1, RSK1, P70S6K, and SGK. Synonyms: 2-Piperidineacetamide, 5-[[[5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-furanyl]carbonyl]amino]-4-(3,4-difluorophenyl)-N-methyl-, (2S,4S,5S)-. CAS No. 2374740-21-1. Molecular formula: C23H23Cl2F2N5O3. Mole weight: 526.36. | |
| AKT-IN-5 | AKT-IN-5 is an inhibitor of Akt1 and Akt2 with IC50s of 450 nM and 400 nM, respectively. CAS No. 1402608-05-2. Molecular formula: C23H20N4O2. Mole weight: 384.43. | |
| Akt Inhibitor | The Akt Inhibitor controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| Akt Inhibitor II | The Akt Inhibitor II controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| Akt Inhibitor III | The Akt Inhibitor III controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| Akt Inhibitor, Isozyme-selective (1,3-Dihydro-1-(1-((4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one; Akti-1/2) | Cell-permeable. A potent and selective inhibitor of Akt1/Akt2 activity (IC?? = 58nM (Akt1), 210nM (Akt2) and 2.12uM (Akt3) in in vitro kinase assays). The inhibition appears to be pleckstrin homology (PH) domain-dependent. It does not exhibit any inhibitory effect against PH domain-lacking Akts, or other closely related AGC family kinases, PKA, PKC, and SGK, even at concentrations (50uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 612847-09-3. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Akt Inhibitor IV | Akt inhibitor IV is an inhibitor of Akt activation that inhibits Akt-mediated nuclear export of Forkhead box class O transcription factor 1a (FOXO1a; IC50 = 625 nM) and reduces phosphorylation of Akt at Ser473 and Thr308 in a dose-dependent manner. Synonyms: 5-(2-Benzothiazolyl)-3-ethyl-2-[2-(methylphenylamino)ethenyl]-1-phenyl-1H-benzimidazolium iodide. Grade: ≥95%. CAS No. 681281-88-9. Molecular formula: C31H27N4S·I. Mole weight: 614.6. | |
| AKT inhibitor IV | Akt inhibitor-IV (AKTIV) acts as a PI3K-Akt inhibitor at the E isomer (HY-14971), with potent cytotoxicity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AKTIV. CAS No. 681281-88-9. Pack Sizes: 1 mg. Product ID: HY-14971A. | |
| Akt Inhibitor IV - CAS 681281-88-9 | The Akt Inhibitor IV, also referenced under CAS 681281-88-9, controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| Akt Inhibitor VI, Akt-in | The Akt Inhibitor VI, Akt-in controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| AKT inhibitor VIII | AKT inhibitor VIII (AKTi-1/2) is a cell-permeable quinoxaline compound that has been shown to potently, selectively, allosterically, and reversibly inhibit Akt1, Akt2, and Akt3 activity with IC50s of 58 nM, 210 nM, and 2119 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AKTi-1/2. CAS No. 612847-09-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10355. | |
| AKT inhibitor VIII | Akt Inhibitor VIII is a cell-permeable quinoxaline compound that has been shown to potently, selectively, allosterically, and reversibly inhibit Akt1, Akt2, and Akt3 activity. It does not exhibit any inhibitory effect against pleckstrin homology (PH) domain-lacking Akts, AGC family kinases, PKA, PKC or SGK. It also prevails over Akt1/Akt2-mediated resistance to chemotherapeutics in tumor cells and has been shown to block basal and stimulated phosphorylation/activation of Akt1/Akt2 in cultured cells and in mice. Synonyms: AKT inhibitor VIII; AKT-inhibitor-VIII; AKT inhibitor-8; AKT-inhibitor-8; Akt-I 1,2; Akti-1/2. Sigma-A6730. 2H-Benzimidazol-2-one, 1,3-dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]-4-piperidinyl]-. Grade: >98%. CAS No. 612847-09-3. Molecular formula: C34H29N7O. Mole weight: 551.64. | |
| Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2 (1,3-Dihydro-1-(1-((4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one, Akti-1/2) | A cell-permeable, reversible, potent, and selective inhibitor of Akt1/Akt2 activity (IC50=58nM, 210nM, and 2.12uM for Akt1, Akt2, and Akt3, respectively, in in vitro kinase assays). The inhibition is reported to be pleckstrin homology (PH) domain-dependent. It does not exhibit any inhibitory effect against PH domain-lacking Akts, or other closely related AGC family kinases, PKA, PKC, and SGK, even at concentrations as high as 50uM. Overcomes Akt1/Akt2-mediated resistance to chemotherapeutics in tumor cells and is shown to block basal and stimulated phosphorylation / activation of Akt1/Akt2 both in cultured cells in vitro and in mice in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 612847-09-3. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2 - CAS 612847-09-3 | Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2, CAS 612847-09-3, is a cell-permeable, reversible inhibitor of Akt1/Akt2 (IC?? = 58 nM, 210 nM, & 2.12 μM for Akt1, Akt2, and Akt3, respectively). Group: Fluorescence/luminescence spectroscopy. | |
| Akt Inhibitor VII, TAT-Akt-in | The Akt Inhibitor VII, TAT-Akt-in controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| Akt Inhibitor X - CAS 925681-41-0 | The Akt Inhibitor X, also referenced under CAS 925681-41-0, controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| Akt Inhibitor XIII, Isozyme-Selective, Akti2-1/2 | The Akt Inhibitor XIII, Isozyme-Selective, Akti2-1/2 controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| Akt Inhibitor XII, Isozyme-Selective, Akti-2 | The Akt Inhibitor XII, Isozyme-Selective, Akti-2 controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| Akt Inhibitor XIV - CAS 1191951-57-1 | The Akt Inhibitor XIV, also referenced under CAS 1191951-57-1, controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| Akt Inhibitor XIX, 3CAI (2-Chloro-1-(1H-indol-3-yl)-ethanone, 3-Chloroacetyl-indole) | A cell-permeable chloroacetyl-indole compound that inhibits Akt1 and Akt2 kinase activity (IC50 <1uM) by directly targeting Akt PH domain, exhibiting little or much reduced activity against a panel of 84 other kinases. Effectively inhibits Akt-mediated downstream effector proteins phosphorylation in a time-dependent manner, resulting in effective apoptosis induction in HCT116 and HT29 cultures (by 55% and 60%, respectively; 4uM for 4 days). Reported to retard HCT116-derived tumor growth in mice (EC50=30mg/kg; 5 times/wk for 3 wks via p.o.) in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 28755-03-5. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Akt Inhibitor XIX, 3CAI - CAS 28755-03-5 | The Akt Inhibitor XIX, 3CAI, also referenced under CAS 28755-03-5, controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| Akt Inhibitor XVI, AT7867 (p70S6K Inhibitor III, 4-(4-Chlorophenyl)-4-(4-(1H-pyrazol-4-yl)-phenyl)-piperidine, PKA Inhibitor XIV, Chlorophenyl-pyrazolyl-phenyl-piperidine, S6K1 Inhibitor III) | A cell-permeable pyrazolo compound that acts as a potent inhibitor against Akt (IC50 = 32, 17, and 47nM against Akt1, Akt2, and Akt3, respectively), PKA (IC50 = 20nM), and p70S6K (IC50 = 85nM) in an ATP-competitive manner (Ki = 18nM using AKT2), with much reduced potency toward RSK1 (IC50 >100nM) and a panel of 13 other cellular kinases (IC50 >1uM). Shown to reduce cellular phosphorylation of GSK-3beta (IC50 range from 2.08 to 4.45uM), S6R, FKHRL1, and inhibit the proliferation of cancer cells exhibiting constitutive Akt pathway activation both in vitro (IC50 range from 0.94 to 11.86uM) and in mice in vivo (20mg/kg via i.p. or 90mg/kg via p.o.). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??ClN?. US Biological Life Sciences. | Worldwide |
| Akt Inhibitor XVIII, SC66 | The Akt Inhibitor XVIII, SC66 controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| Akt Inhibitor XV, Isozyme-Selective | The Akt Inhibitor XV, Isozyme-Selective controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| Aktinolith | Aktinolith. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Asbestos, actinolite;Asbestos actinolite fibers/cc or ml;actinolite, nonasbestiform. Product Category: Heterocyclic Organic Compound. CAS No. 77536-66-4. Product ID: ACM77536664. Alfa Chemistry ISO 9001:2015 Certified. | |
| AKT Kinase Inhibitor | AKT Kinase Inhibitor is an Akt kinase inhibitor with anti-tumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 842148-40-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-10249A. | |
| AKT Kinase Inhibitor | AKT Kinase Inhibitor is a Akt Kinase Inhibitor. Synonyms: 2-Propyn-1-ol, 3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-. Grade: >98%. CAS No. 842148-40-7. Molecular formula: C16H19N7O3. Mole weight: 357.37. | |
| AKT Kinase Inhibitor hydrochloride | AKT Kinase Inhibitor hydrochloride is an Akt kinase inhibitor with anti-tumor activity [1]. AKT Kinase Inhibitor (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 3026697-00-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10249D. | |
| AK-toxin I | It is produced by the strain of Alternaria kikuchiana AS-1223. It's a plant toxin (especially for pear trees). Synonyms: CTK3E8898; (2E,4E,6E)-8-(2-acetamido-3-phenyl-butanoyl)oxy-8-(2-methyloxiran-2-yl)octa-2,4,6-trienoic Acid. Grade: 95%. CAS No. 85146-09-4. Molecular formula: C23H27NO6. Mole weight: 413.46. | |
| AK-toxin ll | It is produced by the strain of Alternaria kikuchiana AS-1223. It's a plant toxin (especially for pear trees). Synonyms: L-Phenylalanine, N-acetyl-, 7-carboxy-1-(2-methyloxiranyl)-2,4,6-heptatrienyl ester, (2S-(2R*(1S*,2E,4Z,6E)))-. Grade: 95%. CAS No. 85146-10-7. Molecular formula: C22H25NO6. Mole weight: 399.44. | |
| Akt/SKG Substrate Peptide | Akt/SKG Substrate Peptide is a synthetic peptide and used as a substrate for Akt/PKB. It could not be phosphorylated by MAP kinase or p70 S6 kinase activated protein kinase-1. Synonyms: N5-(Diaminomethylene)-L-ornithyl-L-prolyl-N5-(diaminomethylene)-L-ornithyl-L-alanyl-L-alanyl-L-threonyl-L-phenylalanine. CAS No. 276680-69-4. Molecular formula: C36H59N13O9. Mole weight: 817.95. | |
| Akt/SKG Substrate Peptide | Akt/SKG Substrate Peptide. Group: Biochemicals. Grades: Purified. CAS No. 276680-69-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| AL-034 | AL-034 is a Toll-like receptor 7 (TLR7) agonist in a phase I clinical trial for the treatment of HBV infections. Uses: The potential treatment of hbv infections. Synonyms: AL-034; AL 034; AL034. | |
| AL-072 | AL072 is an antibiotic against Legionella produced by Strepyomyces sp. AL91. It has strong anti-legionella pneumophila activity. CAS No. 168482-44-8. Molecular formula: C41H76O5. Mole weight: 649.04. | |
| AL 082D06 | AL 082D06, also called as D-06, is a selective nonsteroidal antagonist of glucocorticoid receptor (GR) (Ki= 210 nM) without significant activity on AR, PR, MR and ER(Ki > 10 uM). AL 082D06 binds competitively with steroids, likely occupying a similar site. Synonyms: AL082D06; AL-082D06; AL 082D06; D-06. CAS No. 256925-03-8. Molecular formula: C23H24ClN3O2. Mole weight: 409.91. | |
| Al2O3 Alumina Spherical Powder / Aluminum Oxide Spherical Powder | Al2O3 Alumina Spherical Powder / Aluminum Oxide Spherical Powder. Group: Oxides nanoparticles. CAS No. 1344-28-1. Molecular formula: 101.96 g/mol. 99.9%. |  |
| AL-3152 | AL-3152 is a aldehyde reductase inhibitors originated by Alcon. But clinical trials was discontinued for the treatment of Diabetic nephropathies, Diabetic neuropathies and Diabetic retinopathy. Uses: Diabetic nephropathies; diabetic neuropathies; diabetic retinopathy. Synonyms: AL-3152; AL 3152; AL3152; 2,7-difluoro-4-methoxy-Spiro(9H-fluorene-9,4'-imidazolidine)-2',5'-dione. Grade: 98%. CAS No. 126048-33-7. Molecular formula: C16H10F2N2O3. Mole weight: 316.62. | |
| AL-321 | AL-321 is a bio-active chemical, but no detailed information has been published yet. Synonyms: AL-321; AL321; AL 321; 5-((4-(2-methyl-2-phenylpropoxy)phenyl)methyl)- 2,4-Thiazolidinedione. Grade: 98%. CAS No. 74772-68-2. Molecular formula: C20H21NO3S. Mole weight: 355.45. | |
| AL 34662 | AL 34662 is a potent 5-HT2 receptor agonist with ocular hypotensive activity. Uses: Serotonin 5-ht2 receptor agonists. Synonyms: AL 34497; 1-((S)-2-aminopropyl)-1H-indazol-6-ol; 1H-Indazol-6-ol, 1-[(2S)-2-aminopropyl]-. Grade: ≥98%. CAS No. 210580-75-9. Molecular formula: C10H13N3O. Mole weight: 191.2. | |
| AL-3803 | AL-3803, a spiro derivative, has been found to have some extent of biological activity in drug researches. Synonyms: AL-3803; AL 3803; AL3803; (-)-AL03152; AC1MIXPX; (-)-AL03152; Spiro(9H-fluorene-9,4'-imidazolidine)-2',5'-dione, 2,7-difluoro-4-methoxy-, (S)-; (9S)-2,7-difluoro-4-methoxyspiro[fluorene-9,5'-imidazolidine]-2',4'-dione. Grade: 98%. CAS No. 145555-03-9. Molecular formula: C16H10F2N2O3. Mole weight: 316.26. | |
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