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| Product | Description | |
|---|---|---|
| AG-09/1 | AG-09/1. Synonyms: 2-[(6-methoxy-1H-benzimidazol-2-yl)thio]-N-(4-nitrophenyl)-acetamide. CAS No. 356776-32-4. Molecular formula: C16H14N4O4S. Mole weight: 358.37. |  |
| AG-1024 | AG-1024 is also called Tyrphostin, is a selective inhibitor of IGF-1R. AG-1024 was used to evaluate effects on proliferation, radiosensitivity, and radiation-induced cell apoptosis in a human breast cancer cell line MCF-7. Exposure to Tyrphostin AG 1024 inhibited proliferation and induced apoptosis in a time-dependent manner, and the degree of growth inhibition for IC20 plus irradiation (4 Gy) was up to 50% compared to the control. Synonyms: AG1024; AG-1024; AG 1024. Tyrphostin. Grade: >98%. CAS No. 65678-07-1. Molecular formula: C21H27N7O. Mole weight: 393.23. | |
| AG 1024 - CAS 65678-07-1 | A cell-permeable, reversible, substrate competitive, and specific inhibitor of insulin-like growth factor-1 (IGF-1) and insulin receptor tyrosine kinase activity. Group: Fluorescence/luminescence spectroscopy. |  |
| AG 126 | Tyrphostins are protein tyrosine kinase inhibitors developed to inhibit cell growth through blocking the activity of certain GFRK (growth factor receptor kinases). AG 126 selectively inhibits the phosphorylation of ERK1 and ERK2 at 25-50 μM. It also inhibits the production of TNF-α (tumor necrosis factor-α), attenuating signaling through NF-κB, the induced expression of COX-2 and iNOS, and the inflammatory response in animal models. AG 126 is a poor inhibitor of epidermal GFRK with IC50 of 450 μM and platelet-derived GFRK with IC50 > 100 μM. AG 126 may represent a new approach for the therapy of inflammation. Uses: Anti- inflammation. Synonyms: AG126; AG-126; Tyrphostin AG 126; UNII-7YA4AMD1JC; Tyrphostin A 10; alpha-Cyano-(3-hydroxy-4-nitro)cinnamonitrile. Grade: 95%. CAS No. 118409-62-4. Molecular formula: C10H5N3O3. Mole weight: 215.16. | |
| AG 126 - CAS 118409-62-4 | A cell-permeable inhibitor of lipopolysaccharide (LPS)-induced synthesis of tumor necrosis factor-? and nitric oxide in murine peritoneal macrophages. Group: Fluorescence/luminescence spectroscopy. | |
| AG1295 | Tyrphostin AG 1295 is a selective inhibitor of PDGFR (platelet-derived growth factor receptor) protein tyrosine kinase (PDGF-receptor PTK)(IC50 = 500 nM) and PDGF-dependent DNA synthesis (IC50 = 2.5 μM) in Swiss/3T3 cells. Synonyms: AG1295; AG 1295; AG 1295; NSC 380341; NSC380341; NSC-380341; Tyrphostin AG 1295. Grade: >98%. CAS No. 71897-07-9. Molecular formula: C16H14N2. Mole weight: 234.30. | |
| AG-1295 | AG-1295. Group: Biochemicals. Alternative Names: 6,7-Dimethyl-2-phenyl-quinoxaline; 2-Phenyl-6,7-dimethylquinoxaline; 6,7-Dimethyl-2-phenylquinoxaline; AG 1295; NSC 380341; Tyrphostin AG 1295. Grades: Highly Purified. CAS No. 71897-07-9. Pack Sizes: 10mg. Molecular Formula: C16H14N2, Molecular Weight: 234.3. US Biological Life Sciences. |  Worldwide |
| AG 1295 - CAS 71897-07-9 | A cell-permeable, reversible, ATP-competitive, and selective inhibitor of platelet-derived growth factor (PDGF) receptor kinase (IC?? = 500 nM) and PDGF-dependent DNA synthesis (IC?? = 2.5 μM) in Swiss/3T3 cells. Group: Fluorescence/luminescence spectroscopy. | |
| AG 1296 - CAS 146535-11-7 | A cell-permeable, reversible, and ATP-competitive, inhibitor of PDGF receptor kinase and blocks signaling of human PDGF ?-receptors and ?-receptors. Group: Fluorescence/luminescence spectroscopy. | |
| AG 13958 | AG 13958 is a VEGFR tyrosine kinase inhibitor used for treatment of age-related macular degeneration (AMD). Synonyms: AG-13958; AG13958. CAS No. 319460-94-1. Molecular formula: C26H22FN7O. Mole weight: 467.50. | |
| AG 1406 | AG 1406 is an inhibitor of tyrosine phosphorylation. Synonyms: 2-[[4-hydroxy-3,5-di(propan-2-yl)phenyl]methylidene]propanedinitrile; Propanedinitrile, [[4-hydroxy-3,5-bis(1-methylethyl)phenyl]methylene]-; CTK2G2659; AG1406; CTK2G 2659; AG 1406; CTK2G-2659; AG-1406. CAS No. 71308-34-4. Molecular formula: C16H18N2O. Mole weight: 254.333. | |
| AG-14361 | AG14361 is a PARP-1 inhibitor with Ki < 5 nmol/L. AG14361 is at least 1000-fold more potent than the benzamides. The IC50 for AG14361 is 29 nM in permeabilized SW620 cells and 14 nM in intact SW620 cells. Synonyms: AG14361; AG-14361; AG 14361. Grade:>98%. CAS No. 328543-09-5. Molecular formula: C19H20N4O. Mole weight: 320.39. | |
| AG-1478 | AG-1478 (Tyrphostin AG-1478) is a selective EGFR tyrosine kinase inhibitor with IC 50 of 3 nM. AG-1478 has antiviral effects against HCV and encephalomyocarditis virus (EMCV). Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tyrphostin AG-1478; NSC 693255. CAS No. 153436-53-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13524. |  |
| AG-1478 | AG-1478 (NSC 693255) is a selective EGFR inhibitor with IC50 of 3 nM; almost no activity on HER2-Neu, PDGFR, Trk, Bcr-Abl and InsR. Uses: Enzyme inhibitors. Synonyms: Tyrphostin AG-1478; AG-1478; AG1478; AG 1478. Grade: >98%. CAS No. 153436-53-4. Molecular formula: C16H14ClN3O2. Mole weight: 315.75. | |
| AG 1478 - CAS 175178-82-2 | A cell-permeable, reversible, ATP-competitive, highly potent and selective inhibitor of epidermal growth factor receptor kinase versus HER2-neu and platelet-derived growth factor receptor kinase. Group: Fluorescence/luminescence spectroscopy. | |
| AG 1478 hydrochloride | The hydrochloride salt form of AG 1478, which has been found to be an epidermal growth factor receptor tyrosine kinase inhibitor. Synonyms: AG 1478 hydrochloride; AG1478 hydrochloride; AG-1478 hydrochloride; N-(3-Chlorophenyl)-6,7-dimethoxy-4-quinazolinanine hydrochloride. Grade: ≥98% by HPLC. CAS No. 170449-18-0. Molecular formula: C16H14ClN3O2.HCl. Mole weight: 352.22. | |
| AG-1557 | AG-1557 is an inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase. Synonyms: AG-1557; AG 1557; AG1557; N-(3-Iodophenyl)-6,7-dimethoxyquinazolin-4-amine. CAS No. 189290-58-2. Molecular formula: C16H14IN3O2. Mole weight: 407.211. | |
| AG-1557 hydrochloride | AG-1557 hydrochloride is a specific and ATP competitive inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase. Synonyms: AG 1557 hydrochloride; AG1557 hydrochloride. Molecular formula: C16H15ClIN3O2. Mole weight: 443.66. | |
| AG-17724 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| AG 17 - CAS 10537-47-0 | Anti-proliferative agent that acts as a selective inhibitor of the platelet-derived growth factor receptor tyrosine kinase (IC?? = 500 nM). Group: Fluorescence/luminescence spectroscopy. | |
| AG 18 | AG 18. Group: Biochemicals. Grades: Purified. CAS No. 118409-57-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AG-18 | AG 18 (10 μM) inhibits EGF-induced proliferation of GH3 cells. Synonyms: RG-50810; RG 50810; RG50810; Tyrphostin A23; AG-18; AG 18; AG18; TX 825; Tyrphostin A23; Tyrphostin AG-18. Grade: >98%. CAS No. 118409-57-7. Molecular formula: C10H6N2O2. Mole weight: 186.17. | |
| AG-1801 | AG-1801is a bio-active chemical for treatment of cell proliferative diseases. Synonyms: (E)-N-benzyl-2-cyano-3-(4-nitrophenyl)prop-2-enamide; UNII-WYN000A4MH; STK361572; AG-1801; AG1801; AG 1801. Grade: >98%. CAS No. 204010-55-9. Molecular formula: C17H13N3O3. Mole weight: 307.3. | |
| AG 1812 | This active molecular is a bio-active chemical and detailed information has not been published yet. Synonyms: AG 1812; AG1812; AG-1812; 2-[2-[[[1-(1H-benzimidazol-2-yl)-3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-1-ium-2-yl]methyldisulfanyl]methyl]-3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-1-ium-1-yl]-1H-benzimidazole; dichloride. Grade: 98%. CAS No. 114559-57-8. Molecular formula: C32H28Cl2F6N6O2S2. Mole weight: 777.63. | |
| AG-1812 Free base | AG-1812 is a Lansoprazole disulfide active metabolite. Synonyms: AG-1812; AG 1812; AG1812; 2,2'-(dithiobis(methylene))bis(1-(1H-benzimidazol-2-yl)-3-methyl-4-(2,2,2-trifluoroethoxy)-Pyridinium; Lansoprazole disulfide active metabolite; UNII-6RI44GB0V9; AC1MIZB6; HE078804. Grade: 98%. CAS No. 700341-80-6. Molecular formula: C32H28F6N6O2S22+. Mole weight: 706.73. | |
| AG-183 | AG-183 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 0.8 μM in the human epidermoid carcinoma cell line A431. Synonyms: Tyrphostin 51; Tyrphostin AG 183. Grade: ≥98%. CAS No. 122520-90-5. Molecular formula: C13H8N4O3. Mole weight: 268.2. | |
| AG 18 - CAS 118409-57-7 | A broad-spectrum protein tyrosine kinase inhibitor. Group: Fluorescence/luminescence spectroscopy. | |
| AG 1-X2 ion exchange resin 200-400 acetate | AG 1-X2 ion exchange resin 200-400 acetate. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| AG2000 Free Base | AG2000 Free Base is a bio-active chemical compound. It is also a lansoprazole sulfenamide active metabolite. Synonyms: AG-2000 Free Base; AG2000 Free Base; 4-Methyl-3-(2,2,2-trifluoroethoxy)-5H-pyrido[1',2':4,5][1,2,4]thiadiazino[2,3-a]benzimidazol-13-ium; AG-2000 free base; Lansoprazole sulfenamide active metabolite. Grade: >98%. CAS No. 111712-15-3. Molecular formula: C16H13F3N3OS+. Mole weight: 352.35. | |
| AG 205 | AG 205 is a progesterone receptor membrane component 1 (Pgrmc1) ligand. It inhibits cell cycle progression and cell viability in cancer cell lines. It inhibits progesterone induced cytosolic Ca2+ increases in GnRH neurons in vitro. Synonyms: Cis-2-[[1-(4-Chlorophenyl)-1H-tetrazol-5-yl]thio]-1-(1,2,3,4,4a,9b-hexahydro-2,8-dimethyl-5H-pyrido[4,3-b]indol-5-yl)-ethanone. Grade: ≥98%. CAS No. 442656-02-2. Molecular formula: C22H23ClN6OS. Mole weight: 454.98. | |
| AG-213 | AG-213 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 2.4 μM in the human epidermoid carcinoma cell line A431. Uses: Enzyme inhibitors. Synonyms: Tyrphostin AG-213; Tyrphostin 47; (E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enethioamide. Grade: ≥97%. CAS No. 122520-86-9. Molecular formula: C10H8N2O2S. Mole weight: 220.2. | |
| AG-270 | AG-270 is an allosteric, noncompetitive, first-in-class, reversible and orally active MAT2A inhibitor, with an IC50 of 14 nM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2201056-66-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138630. | |
| AG28262 | AG28262 is a bio-active chemical compound. It is a VEFG-r2 inhibitor and could cause an increase in serum ALT, due in part to both gene up-regulation. Synonyms: AG-28262; AG 28262; AG28262; Benzo(b)thiophene-3-carboxamide, N,2-dimethyl-6-((2-(1-methyl-1H-imidazol-2-yl)thieno(3,2-b)pyridin-7-yl)oxy)-; N,2-dimethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxy-1-benzothiophene-3-carboxamide. Grade: 98%. CAS No. 638216-89-4. Molecular formula: C22H18N4O2S2. Mole weight: 434.53. | |
| AG-348 sulfate hydrate | AG-348 sulfate hydrate is an orally active pyruvate kinase allosteric activator. Synonyms: Mitapivat hemisulfate sesquihydrate; AG-348 hemisulfate sesquihydrate; Pyrukynd; 8-Quinolinesulfonamide, N-(4-((4-(cyclopropylmethyl)-1-piperazinyl)carbonyl)phenyl)-, sulfate, hydrate (2:1:3). CAS No. 2151847-10-6. Molecular formula: C48H60N8O13S3. Mole weight: 1053.23. | |
| AG-370 | AG-370 is a selective inhibitor of PDGF receptor kinase with an IC50 value of 20 μM in human bone marrow fibroblasts. It displays comparatively weak inhibition of the EGF receptor (IC50 = 820 μM). Synonyms: NSC 651712; 2-pentenetricarbonitrile, 3-amino-4-(1h-indol-5-ylmethylene)-. Grade: ≥95%. CAS No. 134036-53-6. Molecular formula: C15H9N5. Mole weight: 259.3. | |
| AG490 | AG490 (Tyrphostin AG490) is a tyrosine kinase inhibitor that inhibits EGFR, Stat-3 and JAK2/3. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tyrphostin AG490; Tyrphostin B42. CAS No. 133550-30-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-12000. | |
| AG 490 | AG 490. Group: Biochemicals. Grades: Purified. CAS No. 133550-30-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AG-490 | Tyrphostin AG490 is a JAK-2 specific inhibitor, which inhibits phosphorylation of EGFR and signal transducer and activator of transcription 3 [STAT-3], and subsequently reduce invasion and adhesion potential of malignant cells. Uses: Antineoplastic agents. Synonyms: Tyrphostin AG 490; AG-490; AG490. Grade: 0.98. CAS No. 133550-30-8. Molecular formula: C17H14N2O3. Mole weight: 294.31. | |
| AG-490 | AG-490. Group: Biochemicals. Alternative Names: 2-Cyano-3-(3,4-dihydroxyphenyl)-N-(phenylmethyl)-2-propenamide; Tyrphostin B 42. Grades: Highly Purified. CAS No. 134036-52-5. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C17H14N2O3. US Biological Life Sciences. | Worldwide |
| AG 490 - CAS 133550-30-8 | A cell-permeable, reversible, substrate competitive, and potent inhibitor of epidermal growth factor receptor kinase autophosphorylation (IC?? = 100 nM). Group: Fluorescence/luminescence spectroscopy. | |
| AG 490, m-CF? - CAS 581797-29-7 | A cell-permeable, reversible, substrate competitive, m-trifluoromethyl derivative of AG 490 that displays apoptotic and antiproliferative properties. Group: Fluorescence/luminescence spectroscopy. | |
| AG 490 (Tyrphostin B42, N-benzyl-3, 4-dihydroxy-benzylidene cyanoacetamide) | Specific and potent JAK2 protein tyrosine kinase inhibitor. Also, inhibits EGF receptor autophosphorylation, with IC50 of 100nM. Inhibits DNA synthesis and cell growth; induces apoptosis. Blocks growth of leukemic cells in vitro and in vivo. Group: Biochemicals. Alternative Names: Tyrphostin B42. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| AG 494 | AG 494. Group: Biochemicals. Grades: Purified. CAS No. 133550-35-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AG 494 | AG-494 is a EGFR (epidermal growth factor receptor) kinase inhibitor with IC50 value of 0.7 μM. It is selective over ErbB2, PDGFR and insulin receptor kinase (IC50 values are 42, 6 and > 100 μM respectively). AG-494 tyrphostin also can block Cdk2 activation. Synonyms: alpha-Cyano-(3,4-dihydroxy)-N-phenylcinnamide; Tyrphostin AG-494; Tyrphostin B48. Grade: 98%. CAS No. 139087-53-9. Molecular formula: C16H12N2O3. Mole weight: 280.28. | |
| AG 538 | AG 538 is a potent, competitive inhibitor of IGF-1 receptor kinase, with an IC 50 of 400 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 133550-18-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135436. | |
| AG 538 - CAS 133550-18-2 | A potent, cell-premeable, reversible, and competitive inhibitor of IGF-1 receptor kinase (IC?? = 400 nM). Group: Fluorescence/luminescence spectroscopy. | |
| AG-5507 | AG-5507 is a bio-active chemical howerver, its detailed information has not been published. Uses: A bio-active chemical. Synonyms: AG-5507; AG5507; AG 5507; UNII-I518B5DK9I; (7R,11S)-2-(3,5-dimethoxyphenyl)-12-(2-(3,5-dimethoxyphenyl)-2-oxoacetyl)-8,9,10,11-tetrahydro-2H-7,11-epiminopyrazino[1,2-a]azocine-3,6(4H,7H)-dione. Grade: ≥95%. CAS No. 294865-05-7. Molecular formula: C28H29N3O8. Mole weight: 535.19. | |
| AG 555 | AG 555 is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (IC50 = 0.7 μM) with 50-fold and >140-fold selectivity over ErbB2 and insulin receptor kinase respectively. Synonyms: AG 555; AG-555; AG555; (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)prop-2-enamide; AG 555; AG-555; alpha-cyano-(3,4-dihydroxy)-N-(3-phenylpropyl)cinnamide; N-(3'-Phenylpropyl)-3,4-dihydroxybenzylidenecyanoacetamide; N-(3-phenylpropyl)-3,4-dihydroxybenzylidene cyanoacetamide; tyrphostin AG 555; tyrphostin AG-555; tyrphostin B46. Grade: ≥98% (HPLC). CAS No. 133550-34-2. Molecular formula: C19H18N2O3. Mole weight: 322.36. | |
| AG 555 | AG 555. Group: Biochemicals. Grades: Purified. CAS No. 133550-34-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AG 556 | AG 556. Group: Biochemicals. Grades: Purified. CAS No. 133550-41-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AG 556 | AG 556, a dihydroxyphen derivative, has been found to be a EGFR kinase inhibitor that could probably be effective in the study of myocardial infarct and hemodynamic deterioration. IC50: 1.1 μM. Synonyms: AG556; AG-556; CHEMBL440298; (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-phenylbutyl)prop-2-enamide. Grade: 98%. CAS No. 133550-41-1. Molecular formula: C20H20N2O3. Mole weight: 336.38. | |
| AG-636 | AG-636 is an orally available inhibitor of dihydroorotate dehydrogenase (DHODH) with strong in vitro and in vivo anti-tumor activity. AG-636 has benn identified as a drug candidate for the treatment of patients with advanced lymphoma. Synonyms: AG 636; AG636. CAS No. 1623416-31-8. Molecular formula: C21H17N3O2. Mole weight: 343.38. | |
| AG-7404 | AG-7404 is an inhibitor of picornaviral 3C protease against a large panel of programmatically important poliovirus strains. AG-7404 was fully active against all V-073-resistant variants with EC50 values ranging from 0.218 to 0.819 μM. Synonyms: AG-7404; 343565-99-1; VQ1AN3OO42; imocitrelvir; UNII-VQ1AN3OO42; V-7404; AG7404; AG 7404; ethyl (E,4S)-4-[[(2S)-2-[3-[(5-methyl-1,2-oxazole-3-carbonyl)amino]-2-oxopyridin-1-yl]pent-4-ynoyl]amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate; (S,E)-ethyl 4-((S)-2-(3-(5-methylisoxazole-3-carboxamido)-2-oxopyridin-1(2H)-yl)pent-4-ynamido)-5-((S)-2-oxopyrrolidin-3-yl)pent-2-enoate; imocitrelvir [INN]; C. Grade: 98% by HPLC. CAS No. 343565-99-1. Molecular formula: C12H11FN5Na4O12P3. Mole weight: 621.12. | |
| AG-7404 | AG-7404 is a potent protease inhibitor with Anti-poliovirus activity. AG-7404 was active against all virus with EC50 values ranging from 0.080 to 0.674 μM. AG-7404 was fully active against all V-073-resistant variants, with EC50 values ranging from 0.218 to 0.819 μM, compared to values of 0.202-0.407 μM for the V-073-susceptible parental strains. In vitro drug combination experiments demonstrated synergy between AG-7404 and either V-073 or BTA798, whereas the combination of the two capsid inhibitors acted additively. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AG-7404; AG 7404; AG7404; V 7404; V-7404; V7404. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 343565-99-1. Molecular formula: C26H29N5O7. Mole weight: 523.55. Purity: >98%. IUPACName: (S,E)-ethyl 4-((S)-2-(3-(5-methylisoxazole-3-carboxamido)-2-oxopyridin-1(2H)-yl)pent-4-ynamido)-5-((S)-2-oxopyrrolidin-3-yl)pent-2-enoate. Canonical SMILES: O=C(OCC)/C=C/[C@@H](NC([C@@H](N1C=CC=C(NC(C2=NOC(C)=C2)=O)C1=O)CC#C)=O)C[C@H]3C(NCC3)=O. Product ID: ACM343565991. Alfa Chemistry ISO 9001:2015 Certified. |  |
| AG-82 | AG-82 is an inhibitor of epidermal growth factor receptor kinase with an IC50 value of 3 μM in the human epidermoid carcinoma cell line A431. Uses: Antineoplastic agents. Synonyms: NSC 676484; RG-50875; Tyrphostin 25; Tyrphostin AG-82. Grade: ≥95%. CAS No. 118409-58-8. Molecular formula: C10H6N2O3. Mole weight: 202.2. | |
| AG 825 | AG 825, a selective ErbB2 (Neu) inhibitor, could probably show activities in triggerring p38 MAP kinase-dependent apoptosis at some extent. Synonyms: AG 825; AG825; AG-825; (E)-3-[3-[2-Benzothiazolythio)methyl]-4-hydroxy-5-methoxyphenyl]-2-cyano-2-propenamide. Grade: ≥95% by HPLC. CAS No. 149092-50-2. Molecular formula: C19H15N3O3S2. Mole weight: 397.47. | |
| AG 825 | AG 825. Group: Biochemicals. Grades: Purified. CAS No. 149092-50-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AG 825 - CAS 149092-50-2 | A potent, cell-premeable, reversible, substrate competitive, and selective inhibitor of HER2 (neu/ErbB2; IC?? = 0.35 μM) relative to HER1 (IC??= 19 μM) autophosphorylation. Group: Fluorescence/luminescence spectroscopy. | |
| AG 82 - CAS 118409-58-8 | A cell-permeable, reversible, and competitive inhibitor of substrate binding on protein tyrosine kinases. Group: Fluorescence/luminescence spectroscopy. | |
| AG 879 | AG 879. Group: Biochemicals. Grades: Purified. CAS No. 148741-30-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| AG-879 | AG-879, a tyrphostin compound, is a dual EGFR/HER2 inhibitor that was administered together with androgen withdrawal therapy. It inhibits nerve growth factor (NGF)-dependent TrkA tyrosine phosphorylation in PC-12 cells (IC50 = ~40 μM), HER2-ErbB2 kinase in several breast and ovarian cancer cell lines (IC50 = ~0.5 μM), and the VEGF receptor FLK1 (IC50 = ~1 μM). Synonyms: α-Cyano-(3,5-di-t-butyl-4-hydroxy)thiocinnamide. CAS No. 148741-30-4. Molecular formula: C18H24N2OS. Mole weight: 316.5. | |
| AG 879 - CAS 148741-30-4 | A cell-permeable, reversible, and substrate competitive inhibitor of nerve growth factor (NGF)-dependent p140c-trk tyrosine phosphorylation (EC?? = 10 μM) as well as NGF-induced phospholipase C-?1 phosphorylation. Group: Fluorescence/luminescence spectroscopy. | |
| AG957 | AG957 is commonly used to study Bcr-Abl signaling in the CML K562 cell line. AG957 is also used to study signaling through c-Abl. Synonyms: NSC 654705; Tyrphostin AG957; Benzoic acid, 4-[[(2,5-dihydroxyphenyl)methyl]amino]-, methyl ester. Grade: ≥95%. CAS No. 140674-76-6. Molecular formula: C15H15NO4. Mole weight: 273.3. | |
| AG 99 | AG 99, an EGF receptor tyrosine kinase inhibitor, has been found to show activities in diagnosis, prevention and treatment of cancer. Synonyms: AG 99; AG-99; AG99; (E)-2-Cyano-3-(3,4-dihydroxyphenyl)-2-propenamide. Grade: ≥99% by HPLC. CAS No. 122520-85-8. Molecular formula: C10H8N2O3. Mole weight: 204.18. | |
| AG 99 | AG 99. Group: Biochemicals. Grades: Purified. CAS No. 122520-85-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AGA-(C8R) HNG17, Humanin derivative | AGA-(C8R) HNG17, Humanin derivative, a powerful humanin (HN) derivative, completely inhibits neuronal cell death through Alzheimer's disease-associated insults. Synonyms: Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro. Grade: ≥95%. CAS No. 875910-01-3. Molecular formula: C78H134N20O24. Mole weight: 1736.02. | |
| Ag Ag2Se Core-Shell Nanoparticles | Ag Ag2Se Core-Shell Nanoparticles. Group: Core shell nanoparticles. CAS No. 1302-09-6. Molecular formula: 294.6964 g/mol. 99.9%. |  |
| a-Galactosyl-3-(t-butyldimethylsilyl)-erythro-sphingosine | Galactosylceramides play an important roles in promoting th. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| a-Galactosyl-C16-ceramide (GalCer) | Galactosylceramides play an important roles in promoting th. Group: Biochemicals. Alternative Names: GalCer. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| a-Galactosyl-C18-ceramide | Galactosylceramides play an important roles in promoting th. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
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