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| Product | Description | |
|---|---|---|
| Aflatoxin M1 | An Aspergillus flavus metabolite. Aflatoxin M1 in milk as a secondary metabolite of the Aflatoxin B1 formed in moldy forages. It is cancerogenic, hepatotoxic, and immunosuppressive in animals and man. Group: Biochemicals. Alternative Names: (6aR, 9aR)-2, 3, 6a, 9a-Tetrahydro-9a-hydroxy-4-methoxy-cyclopenta[c]furo[3, 2:4, 5]furo[2, 3-h][1]benzopyran-1, 11-dione; AFM1. Grades: Highly Purified. CAS No. 6795-23-9. Pack Sizes: 250ug. US Biological Life Sciences. |  Worldwide |
| Aflatoxin M1 | It is produced by the strain of Aspergillus flavus, Asp. parasiticus. The compound of aflatoxin has the activity of anti-gram-positive bacteria, inhibits cell mitosis, has the effect of liver necrosis and carcinogenesis, and is a mycotoxin which contaminates food. Synonyms: AFLATOXIN M1; 4-Hydroxyaflatoxin B1; 3020O28I3; CCRIS 15; (6aR, 9aR)-9a-hydroxy-4-methoxy-2, 3, 6a, 9a-tetrahydrocyclopenta[c]furo[3', 2':4, 5]furo[2, 3-h]chromene-1, 11-dione; (6aR-cis)-2, 3, 6a, 9a-tetrahydro-9a-hydroxy-4-methoxycyclopenta[c]furo[3', 2':4, 5]furo[2, 3-h][1]benzopyran-1, 11-dione; CHEBI:78576; Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione,2,3,6a,9a-tetrahydro-9a-hydroxy-4-methoxy-,(6ar,9ar)-. Grades: ≥95%. CAS No. 6795-23-9. Molecular formula: C17H12O7. Mole weight: 328.27. |  |
| Aflatoxin Q1 | Aflatoxin Q1 is a metabolite of Aflatoxin B1. It is created in human body as a in-vivo detoxification process of Aflatoxin B1. Uses: A metabolite of aflatoxin b1; a hepatocarcinogen in many animal models and probably a human carcinogen. it is produced by the predominant forms of cytochrome p 450 enzymes responsible for the biotransformation of afb1. it shows potential predictive value. Synonyms: Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-3-hydroxy-4-methoxy-, (3S,6aR,9aS)-; Cyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-3-hydroxy-4-methoxy-, (3S-(3-alpha,6a-alpha,9a-alpha))-; (3S, 6aR, 9aS)-3-hydroxy-4-methoxy-2, 3, 6a, 9a-tetrahydrocyclopenta[c]furo[3', 2':4, 5]furo[2, 3-h]chromene-1, 11-dione. Grades: ≥98%. CAS No. 52819-96-2. Molecular formula: C17H12O7. Mole weight: 328.27. | |
| Aflatrem | Aflatrem is the secondary metabolite of Aspergillus flavus. It is able to induce degeneration of neuronal processes in hippocampal neurotransmitter systems at low dose. It potentiates the gamma-aminobutyric acid (GABA)-induced chloride current. It is a tremorgenic mycotoxin with acute neurotoxic effect. Synonyms: 4H-3,15a-Epoxy-1-benzoxepino[6',7':6,7]indeno[1,2-b]indol-4-one, 9-(1,1-dimethyl-2-propenyl)-2,3,5b,6,7,7a,8,13,13b,13c,14,15-dodecahydro-5b-hydroxy-2,2,13b,13c-tetramethyl-, (3R,5bS,7aS,13bS,13cR,15aS)-; 9-(1, 1-Dimethyl-2-propenyl)-2, 3, 5b, 6, 7, 7aα, 8, 13, 13b, 13c, 14, 15-dodecahydro-5bβ-hydroxy-2, 2, 13bβ, 13cα-tetramethyl-4H-3β, 15aβ-epoxy-1-benzoxepino[6', 7':6, 7]indeno[1, 2-b]indol-4-one; α,α-dimethylallylpaspalinine. Grades: 98.0%. CAS No. 70553-75-2. Molecular formula: C32H39NO4. Mole weight: 501.66. | |
| Aflavarin | Aflavarin is a metabolite of the Sclerotia of Aspergillus flavus displaying anti-insectan activity against the fungivorous beetle Carpopbilus bemipterus. Synonyms: (3,8'-Bi-2H-1-benzopyran)-2,2'-dione, 5-(hydroxymethyl)-4,4',7,7'-tetramethoxy-5'-methyl-, (-)-; (-)-5-(Hydroxymethyl)-4,4',7,7'-tetramethoxy-5'-methyl[3,8'-bi-2H-1-benzopyran]-2,2'-dione. Grades: 98.0%. CAS No. 144429-67-4. Molecular formula: C24H22O9. Mole weight: 454.43. | |
| Aflavazole | Aflavazole is a metabolite of the sclerotia of Aspergillus flavus. It shows antifeedant activity against the fungivorous beetle Carpophilus hemipterus remarkably. Synonyms: (1R,4S,4aS,13dS,14R,16R,16aS)-1,2,3,4,5,6,9,13d,14,15,16,16a-Dodecahydro-1,7,14,16a-tetramethylphenanthro[2,1-c]carbazole-4,16-diol; (+)-Aflavazole; Benzo(4a,5)naphtho(2,1-c)carbazole-4,16-diol, 1,2,3,4,5,6,9,13d,14,15,16,16a-dodecahydro-1,7,14,16a-tetramethyl-, (1alpha, 4alpha, 4aS*, 13dbeta, 14alpha, 16beta, 16aalpha)-(+)-; Benzo(4a,5)naphtho(2,1-c)carbazole-4,16-diol,1,2,3,4,5,6,9,13d,14,15,16,16a-dodecahydro-1,7,16a-tetramethyl-, (1R,4S,4aS,13dS,14R,16R,16aS)-rel-(+)-. Grades: 97.5%. CAS No. 2043963-70-6. Molecular formula: C28H35NO2. Mole weight: 417.58. | |
| Aflibercept | Aflibercept is a recombinant fusion protein and acts as a VEGF inhibitor. Aflibercept is used for the treatment of wet macular degeneration and metastatic colorectal cancer. Synonyms: Eylea. CAS No. 862111-32-8. Molecular formula: C4318H6788N1164O1304S32. Mole weight: 96898.57. | |
| Aflibercept | Aflibercept (VEGF Trap) is a soluble decoy VEGFR constructed by fusing the Ig domains of VEGFR 1 and VEGFR 2 with the Fc region of human IgG1. Aflibercept inhibits VEGF signaling by reducing VEGF-regulated processes. Aflibercept can be used for thr research of age-related macular degeneration (AMD) and cardiovascular disease [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: VEGF Trap; VEGF-TRAPR1R2; VEGF-trapR1. CAS No. 862111-32-8. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-108801. |  |
| Aflibercept (VEGF Trap) | Aflibercept (VEGF Trap) is a soluble decoy VEGFR constructed by fusing the Ig domains of VEGFR 1 and VEGFR 2 with the Fc region of human IgG1. Aflibercept inhibits VEGF signaling by reducing VEGF-regulated processes. Aflibercept can be used for thr research of age-related macular degeneration (AMD) and cardiovascular disease [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 862111-32-8. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-108801A. | |
| Afloqualone | Afloqualone (HQ-495) is an orally active central muscle relaxant and antivertiginous agent that can increase the sensitivity of GABA receptors in neurons of the lateral vestibular nucleus. Afloqualone (HQ-495) can be used in the research of low back pain and neck-arm-shoulder syndrome [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HQ-495. CAS No. 56287-74-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1833. | |
| Afloqualone | Afloqualone is a agonist of GABA receptor has sedative and muscle-relaxant effects. Uses: A agonist of gaba receptor. Synonyms: HQ-495; HQ495; HQ 495. Afloqualone; 6-amino-2-(fluoromethyl)-3-(2-methylphenyl)quinazolin-4-one. Grades: ≥98%. CAS No. 56287-74-2. Molecular formula: C16H14FN3O. Mole weight: 283.3. | |
| a-Fluoro-b-alanine | a-Fluoro-b-alanine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| a-Fluoro-b-alanine-13C3 ((2R)-3-Amino-2-fluoropropanoic Acid-13C3) | A stable isotope analogue of the catabolism of the anti-cancer drug 5-Flurouracil. Group: Biochemicals. Alternative Names: (2R)-3-Amino-2-fluoropropanoic Acid-13C3. Grades: Highly Purified. CAS No. 1246819-54-4. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| a-Fluorophenylacetonitrile | a-Fluorophenylacetonitrile. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-FLUOROBENZYL CYANIDE 97%;Jrd-0527. Product Category: Heterocyclic Organic Compound. CAS No. 10036-43-8. Molecular formula: C8H6NF. Mole weight: 135.14. Product ID: ACM10036438. Alfa Chemistry ISO 9001:2015 Certified. Categories: 501-00-8. |  |
| a-Fmoc-L-Lys((+)-Biotinyl-e-aminocaproyl)-OH 99+% | a-Fmoc-L-Lys((+)-Biotinyl-e-aminocaproyl)-OH 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| AFN-1252 | AFN-1252 is an enoyl-(acyl-carrier protein) reductase fabl inhibitor, inhibited all clinical isolates of Staphylococcus aureus and Staphylococcus epidermidis at concentrations of ≤0.12 μg/ml. Uses: Antibacterial. Synonyms: AFN-1252; AFN 1252; AFN1252; AFN-12520000; API-1252; Debio-1452; AFN12520000; API1252; Debio1452. (E)-N-methyl-N-[(3-methyl-1-benzofuran-2-yl)methyl]-3-(7-oxo-6,8-dihydro-5H-1,8-naphthyridin-3-yl)prop-2-enamide. Grades: ≥95%. CAS No. 620175-39-5. Molecular formula: C22H21N3O3. Mole weight: 375.43. | |
| AFN-1252 | AFN-1252, also known as AFN-12520000; API-1252; Debio-1452, is FASII Inhibitor which is potentially for the treatment of acute bacterial skin. AFN-1252 exhibits typical MIC(90) values of ≤0·015 μg/ml against diverse clinical isolates of S. aureus, oral absorption, long elimination half-live and efficacy in animal models. AFN-1252 efficiently blocked daptomycin-induced phospholipid decoy production, even in the case of isolates resistant to AFN-1252, which prevented the inactivation of daptomycin and resulted in sustained bacterial killing. In turn, daptomycin prevented the fatty acid-dependent emergence of AFN-1252-resistant isolates in vitro. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AFN-1252; AFN 1252; AFN1252; API-1252; API1252; API 1252; AFN12520000; AFN 12520000; AFN12520000; Debio1452; Debio 1452; Debio1452. Product Category: Inhibitors. Appearance: White to off-white solid powder. CAS No. 620175-39-5. Molecular formula: C22H21N3O3. Mole weight: 375.43. Purity: >98%. IUPACName: (E)-N-methyl-N-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide. Canonical SMILES: O=C(N(C)CC1=C(C)C2=CC=CC=C2O1)/C=C/C3=CC(CC4)=C(N=C3)NC4=O. Product ID: ACM620175395. Alfa Chemistry ISO 9001:2015 Certified. | |
| AFN39186 | AFN39186, also known as RAD51-IN-1, is a derivative of B02 and a potent inhibitor of RAD51. AFN39186 was first reported in Bioorg Med Chem Lett. 2017 Jul 15;27(14):3096-3100. This product has no formal name at the moment. Uses: Designed for use in research and industrial production. Additional or Alternative Names: RAD51-IN-1; AFN39186; AFN-39186; AFN 39186. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2101739-18-6. Molecular formula: C22H16ClN3O. Mole weight: 373.84. Purity: >98%. IUPACName: (E)-3-(4-chlorobenzyl)-2-(2-(pyridin-3-yl)vinyl)quinazolin-4(3H)-one. Canonical SMILES: O=C1N(CC2=CC=C(Cl)C=C2)C(/C=C/C3=CC=CN=C3)=NC4=C1C=CC=C4. Product ID: ACM2101739186. Alfa Chemistry ISO 9001:2015 Certified. | |
| Afobazole | Fabomotizole (brand name Afobazole) is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Fabomotizole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Clinical trials have shown fabomotizole to be well tolerated and reasonably effective for the treatment of anxiety. Experiments of mice have showed antimutagenic and antiteratogenic properties. Synonyms: CM346; Afobazol; Fabomotizole; CM 346; CM-346. Grades: >98%. CAS No. 173352-21-1. Molecular formula: C15H21N3O2S. Mole weight: 307.41. | |
| Afobazole hydrochloride | Fabomotizole (brand name Afobazole) is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Fabomotizole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Clinical trials have shown fabomotizole to be well tolerated and reasonably effective for the treatment of anxiety. Experiments of mice have showed antimutagenic and antiteratogenic properties. Synonyms: CM346 hydrochloride; Afobazol hydrochloride; Fabomotizole hydrochloride; CM 346 hydrochloride; CM-346 hydrochloride. Grades: >98%. CAS No. 173352-39-1. Molecular formula: C15H22ClN3O2S. Mole weight: 343.87. | |
| Afoxolaner | Afoxolaner is a potent isoxazoline insecticide and acaricide against Ixodes scapularis in dogs. It is indicated for the treatment and prevention of flea infestations, and the treatment and control of tick infestations in dogs and puppies. It is administered orally in meat-flavoured tablets, and poisons fleas once they start feeding. It is used either alone or as a combination treatment with milbemycin oxime. Synonyms: 4-[5-[3-Chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-1-naphthalenecarboxamide; 4-[5-[3-Chloro-5- (trifluoromethyl) phenyl]-5- (trifluoromethyl) -4H-1, 2-oxazol-3-yl]-N-[2-oxo-2- (2, 2, 2-trifluoroethylamino) ethyl]naphthalene-1-carboxamide. Grades: >98%. CAS No. 1093861-60-9. Molecular formula: C26H17ClF9N3O3. Mole weight: 625.87. | |
| Afoxolaner | Afoxolaner is an insecticide and acaricide used in dogs to treat and prevent flea infestations. Used to treat specifically the Sarcoptes scabiei var. canis species. Group: Biochemicals. Grades: Highly Purified. CAS No. 1093861-60-9. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C26H17ClF9N3O3, Molecular Weight: 625.87. US Biological Life Sciences. | Worldwide |
| Afoxolaner | Afoxolaner is an orally active isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect γ-aminobutyric acid receptor (GABA) and glutamate receptors , inhibiting GABA & glutamate-regulated uptake of chloride ions , resulting in excess neuronal stimulation and death of the arthropod [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1093861-60-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16974. | |
| AFP 07 | AFP 07 is a 7,7-difluoroprostacyclin derivative that acts as a selective and highly potent agonist for the IP receptor. Synonyms: (5Z)-5-[(3aR,4R,5R,6aS)-3,3-difluoro-5-hydroxy-4-[(E,3S,4S)-3-hydroxy-4-methylnon-1-en-6-ynyl]-4,5,6,6a-tetrahydro-3aH-cyclopenta[b]furan-2-ylidene]pentanoic acid. Grades: ≥98%. CAS No. 788799-13-3. Molecular formula: C22H30F2O5. Mole weight: 412.5. | |
| AFP-464 | AFP-464 is a synthetic lysyl prodrug of the amino-substituted flavone derivate aminoflavone with antiproliferative and antineoplastic activities. AFP464 is rapidly converted to aminoflavone in plasma. Aminoflavone activates the aryl hydrocarbon receptor (AhR) signaling pathway leading to an increase in cytochrome P450 1A1 (CYP1A1) and cytochrome P450 1A2 (CYP1A2) expression and, to a lesser extent, an increase in cytochrome P450 1B1 (CYP1B1) expression. Synonyms: AFP464; AFP 464; Hexanamide, 2,6-diamino-N-(4-(5-amino-6,8-difluoro-7-methyl-4-oxo-4H-1-benzopyran-2-yl)-2-fluorophenyl)-, (2S)-. CAS No. 468719-52-0. Molecular formula: C23H27F3N4O6S. Mole weight: 448.44. | |
| Afragilimycin A | It is produced by the strain of Streptomyces neohygroscopicus sub-sp, afragilimycetius 19255. It has anti-gram-positive bacteria and anti-gram-negative bacteria including anaerobic bacteria activity. Synonyms: Afrigilimycin A; (2S)-4-[(2E,4E,6R)-6-[(1S,2S,3R,5S,6R)-2,5-dimethylspiro[4,9-dioxabicyclo[3.3.1]non-7-ene-6,2'-oxirane]-3-yl]-4-methylhepta-2,4-dienoyl]-1-[(5S,6S)-5-hydroxy-6-methyloxan-2-yl]-2-[(2S)-1-(methylamino)-1-oxopropan-2-yl]-3-oxo-2H-pyrrol-5-olate. CAS No. 76559-69-8. Molecular formula: C32H43N2O9-. Mole weight: 599.69. | |
| African Mango Seed Extract | African Mango Seed Extract. Applications: Used for health care products, dietary supplements, weight loss, reducing blood lipids. Group: Others. Synonyms: African Mango Seed Extract; 9005-80-5; Irvingia GabonensisSeed. CAS No. 9005-80-5. Purity: 20% Phytoprotein By KJELDAHL, 10:1 By TLC. Appearance: Light yellow fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Seed. Species: Irvingia GabonensisSeed. African Mango Seed Extract; 9005-80-5; Irvingia GabonensisSeed; plant extract. Pack: 20KG-25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-103. |  |
| African Mango Seed P.E. 10:1 | African Mango Seed P.E. 10:1 (Irvingia Gabonensis). |  CA, FL & NJ |
| Afromosin | Afromosin is an isoflavone, that can be isolated from Millettia dielsiana Harms. Afromosin exhibits remarkable tumor inhibitory effects [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 550-79-8. Pack Sizes: 1 mg. Product ID: HY-119846. | |
| Afrormosin | Afrormosin is found in the herbs of Mucuna macrocarpa Wallich. Synonyms: Afrormosine. Grades: > 95%. CAS No. 550-79-8. Molecular formula: C17H14O5. Mole weight: 298.29. | |
| Aftin-4 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Aftin-4 (N6-Methyl-(R)-roscovitine, Amyloid-beta Forty-Two Inducer 4) | Roscovitine-related purine with no activity on CDKs (used as control for roscovitine). Selectively and potently increases production of extracellular Abeta42 and decreases production of extracellular Abeta38 in cultured cells. Extracellular Abeta40 levels remain stable. Intracellular levels of these amyloids appear to remain stable. Alzheimer's Disease (AD) accelerator that interacts with VDAC1, prohibitin and mitofilin, possibly interfering with subcellular compartmentalization and lipid rafts properties, shifting gamma-secretase activity toward Abeta42 generation. Induces a reversible mitochondrial phenotype reminiscent of the one observed in AD brains. Tool to detect inhibitors of Aftin-induced actions (potential anti-AD compounds). Binds pyridoxal kinase. Group: Biochemicals. Grades: Highly Purified. CAS No. 866893-90-5. Pack Sizes: 1mg, 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| Aftin-5 ((2R)-2-[[9-Isopropyl-6-(N-methylanilino)purin-2-yl]amino]butan-1-ol, Amyloidbeta Forty-Two Inducer 5) | Roscovitine-related purine with no activity on CDKs (used as control for roscovitine). Selectively and potently increases production of extracellular Ab42 and decreases production of extracellular Ab38 in cultured cells. Extracellular Ab40 levels remain stable. Intracellular levels of these amyloids appear to remain stable. Alzheimer's Disease (AD) accelerator that interacts with VDAC1, prohibitin and mitofilin, possibly interfering with subcellular compartmentalization and lipid rafts properties, shifting gamma-secretase activity toward Ab42 generation. Induces a reversible mitochondrial phenotype reminiscent of the one observed in AD brains. Tool to detect inhibitors of Aftin-induced actions (potential anti-AD compounds). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| Aftobetin Hydrochloride | Aftobetin, also known as ANCA11 and NCE-11, is a novel amyloid-binding compound applied topically in the form of an ophthalmic ointment. Aftobetin may be of useful as an aid in the diagnosis Alzheimer's disease. Synonyms: Aftobetin Hydrochloride; NCE-11; Aftobetin Hydrochloride [USAN]; UNII-A1FCZ940WA; 1353222-83-9; A1FCZ940WA; 11-HCl; 2-Propenoic acid, 2-cyano-3-(6-(1-piperidinyl)-2-naphthalenyl)-, 2-(2-(2-methoxyethoxy)ethoxy)ethyl ester, hydrochloride (1:1), (2E)-; Aftobetin hydrochloride (USAN); 2-(2-(2-Methoxyethoxy)ethoxy)ethyl (2E)-2-cyano-3-(6-(piperidin-1-yl)naphthalen-2-yl)prop-2-enoate monohydrochloride; Aftobetin HCl; 2-[2-(2-Methoxyethoxy)ethoxy]ethyl (2E)-2-cyano-3-[6-(piperidin-1-yl)naphthalen-2-yl]prop-2-enoate monohydrochloride; aftobetin-hydrochloride; ANCA-11 HYDROCHLORIDE; CHEMBL2364602; DTXSID90159314; AKOS040750170; AFTOBETIN HYDROCHLORIDE [WHO-DD]; D10607; Q27273497. CAS No. 1353222-83-9. Molecular formula: C26H33ClN2O5. Mole weight: 489.009. | |
| Afuresertib | Afuresertib, also known as GSK2110183, is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor GSK2110183 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signaling may contribute to tumor resistance to a variety of antineoplastic agents. Synonyms: GSK-2110183; GSK 2110183; GSK2110183; GSK-2110183B; GSK 2110183B; GSK2110183B; Afuresertib. CAS No. 1047644-62-1. Molecular formula: C18H17Cl2FN4OS. Mole weight: 427.32. | |
| Afuresertib | Afuresertib (GSK2110183) is an orally bioavailable, selective, ATP-competitive and potent pan-Akt kinase inhibitor with K i s of 0.08/2/2.6 nM for Akt1/Akt2/Akt3, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK2110183; LAE002. CAS No. 1047644-62-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15727. | |
| Afuresertib HCl | Afuresertib HCl is a potent pan-AKT inhibitor. Synonyms: N-((S)-1-amino-3-(3-fluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide hydrochloride; GSK2110183; GSK 2110183; GSK-2110183; GSK2110183B; GSK 2110183B; GSK2110183B; Afuresertib. Grades: >98%. CAS No. 1047645-82-8. Molecular formula: C18H18Cl3FN4OS. Mole weight: 463.78. | |
| Afuresertib hydrochloride | Afuresertib hydrochloride (GSK 2110183 hydrochloride) is an orally bioavailable, selective, ATP-competitive and potent pan-Akt kinase inhibitor with K i s of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK2110183 hydrochloride; LAE002 hydrochloride. CAS No. 1047645-82-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15727A. | |
| Afutuzumab | Afutuzumab. Uses: Designed for use in research and industrial production. Additional or Alternative Names: afutuzumab;Ga 101;Humab(cd20);Ro 5072759;Ro5072759. Product Category: Heterocyclic Organic Compound. CAS No. 949142-50-1. Product ID: ACM949142501. Alfa Chemistry ISO 9001:2015 Certified. | |
| Afzelin | Afzelin. Group: Biochemicals. CAS No. 482-39-3. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Ag | Ag. Group: Elements nanoparticles. 99.9%. |  |
| AG-012917 | AG-012917 is a broad spectrum cyclin-dependent kinase inhibitor with potential anticancer activity. Synonyms: AG 012917; AG012917; (S)-4-((4-amino-5-(2,6-difluorobenzoyl)thiazol-2-yl)amino)-N-((1-methylpyrrolidin-2-yl)methyl)benzamide. Grades: >98%. CAS No. 486414-16-8. Molecular formula: C23H23F2N5O2S. Mole weight: 471.52. | |
| AG-012986 | AG-012986 is a multitargeted cyclin-dependent kinase (CDK) inhibitor active against CDK1, CDK2, CDK4/6, CDK5, and CDK9, with selectivity over a diverse panel of non-CDK kinases. AG-012986 showed antiproliferative activities in vitro with IC(50)s of <100 nmol/L in 14 of 18 tumor cell lines. In vivo, significant antitumor efficacy induced by AG-012986 was seen (tumor growth inhibition,>83.1%) in 10 of 11 human xenograft tumor models. AG-012986 also showed dose-dependent retinoblastoma Ser(795) hypophosphorylation, cell cycle arrest, decreased Ki-67 tumor staining, and apoptosis in conjunction with antitumor activity. Synonyms: AG 012986; AG012986; Benzamide, 4-((4-amino-5-(2,6-difluorobenzoyl)-2-thiazolyl)amino)-N-((1R)-2-(dimethylamino)-1-methylethyl)-. Grades: >98%. CAS No. 486414-35-1. Molecular formula: C22H23F2N5O2S. Mole weight: 459.51. | |
| AG013736 (AxitinibAxitinib) | Axitinib (also known as AG013736) is a small molecule tyrosine kinase inhibitor under development by Pfizer. It inhibits multiple targets, including VEGFR-1, VEGFR-2, VEGFR-3, platelet derived growth factor receptor (PDGFR), and cKIT (CD117). It has been shown to significantly inhibit growth of breast cancer in xenograft models [1] and has been successful in trials with renal cell carcinoma (RCC) [2] and several other tumor types [3]. Group: Biochemicals. Alternative Names: N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide; AG 013736. Grades: Purified. CAS No. 319460-85-0. Pack Sizes: 50mg, 100mg. US Biological Life Sciences. | Worldwide |
| AG-024104 | AG-024104 is a broad spectrum cyclin-dependent kinase inhibitor with potential anticancer activity. Synonyms: AG 024104; AG024104. Grades: >98%. CAS No. 750575-23-6. Molecular formula: C24H28F2N6O4S2. Mole weight: 566.64. | |
| AG-024322 | AG-24322 is a second generation CDK inhibitor. AG-024322 is a potent inhibitor of CDK1, CDK2, and CDK4 that produces cell-cycle arrest and antitumor activity in preclinical models. Synonyms: AG-24322; AG 24322; AG24322. Grades: 98%. CAS No. 837364-57-5. Molecular formula: C23H20F2N6. Mole weight: 418.44. | |
| AG-041R | AG-041R is a potent gastrin/CCK2 receptor antagonist that exhibits selective binding for CCK2 compared to CCK1. Synonyms: 1H-Indole-3-acetamide, 1-(2,2-diethoxyethyl)-2,3-dihydro-N-(4-methylphenyl)-3-[[[(4-methylphenyl)amino]carbonyl]amino]-2-oxo-, (+)-; (+)-1-(2,2-Diethoxyethyl)-2,3-dihydro-N-(4-methylphenyl)-3-[[[(4-methylphenyl)amino]carbonyl]amino]-2-oxo-1H-indole-3-acetamide; (+)-AG 041R; AG 041R; (R)-2-(1-(2,2-diethoxyethyl)-2-oxo-3-(3-(p-tolyl)ureido)indolin-3-yl)-N-(p-tolyl)acetamide. Grades: ≥98%. CAS No. 159883-95-1. Molecular formula: C31H36N4O5. Mole weight: 544.64. | |
| AG 045572 | AG 045572, a nonpeptidic GnRH antagonist, could probably be used in the treatment for sex hormone-dependent diseases and infertility. Synonyms: AG 045572; AG045572; AG-045572; 5-[5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl-methyl]-N-(2,4,6-trimethoxyphenyl)-2-furancarboxamide. Grades: ≥97% by HPLC. CAS No. 263847-55-8. Molecular formula: C30H37NO5. Mole weight: 491.62. | |
| AG 045572 | AG 045572. Group: Biochemicals. Grades: Purified. CAS No. 263847-55-8. Pack Sizes: 1mg, 10mg. US Biological Life Sciences. | Worldwide |
| AG-09/1 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| AG-1024 | AG-1024 is also called Tyrphostin, is a selective inhibitor of IGF-1R. AG-1024 was used to evaluate effects on proliferation, radiosensitivity, and radiation-induced cell apoptosis in a human breast cancer cell line MCF-7. Exposure to Tyrphostin AG 1024 inhibited proliferation and induced apoptosis in a time-dependent manner, and the degree of growth inhibition for IC20 plus irradiation (4 Gy) was up to 50% compared to the control. Synonyms: AG1024; AG-1024; AG 1024. Tyrphostin. Grades: >98%. CAS No. 65678-07-1. Molecular formula: C21H27N7O. Mole weight: 393.23. | |
| AG 1024 - CAS 65678-07-1 | A cell-permeable, reversible, substrate competitive, and specific inhibitor of insulin-like growth factor-1 (IGF-1) and insulin receptor tyrosine kinase activity. Group: Fluorescence/luminescence spectroscopy. | |
| AG-120 | AG-120 is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity. Synonyms: (2S)-N-(1-(2-chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)-1-(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide; AG-120 (racemic); AG120; AG 120; AG-120; RG-120 (racemic); RG-120, RG 120; Ivosidenib (racemic). Grades: 98%. CAS No. 1448346-63-1. Molecular formula: C28H22ClF3N6O3. Mole weight: 582.97. | |
| AG 126 | Tyrphostins are protein tyrosine kinase inhibitors developed to inhibit cell growth through blocking the activity of certain GFRK (growth factor receptor kinases). AG 126 selectively inhibits the phosphorylation of ERK1 and ERK2 at 25-50 μM. It also inhibits the production of TNF-α (tumor necrosis factor-α), attenuating signaling through NF-κB, the induced expression of COX-2 and iNOS, and the inflammatory response in animal models. AG 126 is a poor inhibitor of epidermal GFRK with IC50 of 450 μM and platelet-derived GFRK with IC50 > 100 μM. AG 126 may represent a new approach for the therapy of inflammation. Uses: Anti- inflammation. Synonyms: AG126; AG-126; Tyrphostin AG 126; UNII-7YA4AMD1JC; Tyrphostin A 10; alpha-Cyano-(3-hydroxy-4-nitro)cinnamonitrile. Grades: 95%. CAS No. 118409-62-4. Molecular formula: C10H5N3O3. Mole weight: 215.16. | |
| AG 126 - CAS 118409-62-4 | A cell-permeable inhibitor of lipopolysaccharide (LPS)-induced synthesis of tumor necrosis factor-? and nitric oxide in murine peritoneal macrophages. Group: Fluorescence/luminescence spectroscopy. | |
| AG1295 | Tyrphostin AG 1295 is a selective inhibitor of PDGFR (platelet-derived growth factor receptor) protein tyrosine kinase (PDGF-receptor PTK)(IC50 = 500 nM) and PDGF-dependent DNA synthesis (IC50 = 2.5 μM) in Swiss/3T3 cells. Synonyms: AG1295; AG 1295; AG 1295; NSC 380341; NSC380341; NSC-380341; Tyrphostin AG 1295. Grades: >98%. CAS No. 71897-07-9. Molecular formula: C16H14N2. Mole weight: 234.30. | |
| AG-1295 | AG-1295. Group: Biochemicals. Alternative Names: 6,7-Dimethyl-2-phenyl-quinoxaline; 2-Phenyl-6,7-dimethylquinoxaline; 6,7-Dimethyl-2-phenylquinoxaline; AG 1295; NSC 380341; Tyrphostin AG 1295. Grades: Highly Purified. CAS No. 71897-07-9. Pack Sizes: 10mg. Molecular Formula: C16H14N2, Molecular Weight: 234.3. US Biological Life Sciences. | Worldwide |
| AG 1295 - CAS 71897-07-9 | A cell-permeable, reversible, ATP-competitive, and selective inhibitor of platelet-derived growth factor (PDGF) receptor kinase (IC?? = 500 nM) and PDGF-dependent DNA synthesis (IC?? = 2.5 μM) in Swiss/3T3 cells. Group: Fluorescence/luminescence spectroscopy. | |
| AG 1296 - CAS 146535-11-7 | A cell-permeable, reversible, and ATP-competitive, inhibitor of PDGF receptor kinase and blocks signaling of human PDGF ?-receptors and ?-receptors. Group: Fluorescence/luminescence spectroscopy. | |
| AG 1406 | AG 1406 is an inhibitor of tyrosine phosphorylation. Synonyms: 2-[[4-hydroxy-3, 5-di (propan-2-yl) phenyl]methylidene]propanedinitrile; Propanedinitrile, [[4-hydroxy-3,5-bis(1-methylethyl)phenyl]methylene]-; CTK2G2659; AG1406; CTK2G 2659; AG 1406; CTK2G-2659; AG-1406. CAS No. 71308-34-4. Molecular formula: C16H18N2O. Mole weight: 254.333. | |
| AG-14361 | AG14361 is a PARP-1 inhibitor with Ki < 5 nmol/L. AG14361 is at least 1000-fold more potent than the benzamides. The IC50 for AG14361 is 29 nM in permeabilized SW620 cells and 14 nM in intact SW620 cells. Synonyms: AG14361; AG-14361; AG 14361. Grades:>98%. CAS No. 328543-09-5. Molecular formula: C19H20N4O. Mole weight: 320.39. | |
| AG-1478 | AG-1478 (NSC 693255) is a selective EGFR inhibitor with IC50 of 3 nM; almost no activity on HER2-Neu, PDGFR, Trk, Bcr-Abl and InsR. Uses: Enzyme inhibitors. Synonyms: Tyrphostin AG-1478; AG-1478; AG1478; AG 1478. Grades: >98%. CAS No. 153436-53-4. Molecular formula: C16H14ClN3O2. Mole weight: 315.75. | |
| AG-1478 | AG-1478 (Tyrphostin AG-1478) is a selective EGFR tyrosine kinase inhibitor with IC 50 of 3 nM. AG-1478 has antiviral effects against HCV and encephalomyocarditis virus (EMCV). Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tyrphostin AG-1478; NSC 693255. CAS No. 153436-53-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13524. | |
| AG 1478 - CAS 175178-82-2 | A cell-permeable, reversible, ATP-competitive, highly potent and selective inhibitor of epidermal growth factor receptor kinase versus HER2-neu and platelet-derived growth factor receptor kinase. Group: Fluorescence/luminescence spectroscopy. | |
| AG 1478 hydrochloride | The hydrochloride salt form of AG 1478, which has been found to be an epidermal growth factor receptor tyrosine kinase inhibitor. Synonyms: AG 1478 hydrochloride; AG1478 hydrochloride; AG-1478 hydrochloride; N-(3-Chlorophenyl)-6,7-dimethoxy-4-quinazolinanine hydrochloride. Grades: ≥98% by HPLC. CAS No. 170449-18-0. Molecular formula: C16H14ClN3O2.HCl. Mole weight: 352.22. | |
| AG-1557 | AG-1557 is an inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase. Synonyms: AG-1557; AG 1557; AG1557; N-(3-Iodophenyl)-6,7-dimethoxyquinazolin-4-amine. CAS No. 189290-58-2. Molecular formula: C16H14IN3O2. Mole weight: 407.211. | |
| AG-1557 hydrochloride | AG-1557 hydrochloride is a specific and ATP competitive inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase. Synonyms: AG 1557 hydrochloride; AG1557 hydrochloride. Molecular formula: C16H15ClIN3O2. Mole weight: 443.66. | |
| AG-17724 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| AG 17 - CAS 10537-47-0 | Anti-proliferative agent that acts as a selective inhibitor of the platelet-derived growth factor receptor tyrosine kinase (IC?? = 500 nM). Group: Fluorescence/luminescence spectroscopy. | |
| AG 18 | AG 18. Group: Biochemicals. Grades: Purified. CAS No. 118409-57-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
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