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Afatinib Impurity 52 is an impurity of Afatinib, a drug used to treat non-small cell lung cancer (NSCLC). Synonyms: (S)-diethyl 2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamino)-2-oxoethylphosphonate; Diethyl {[4-(3-Chloro-4-Fluoro-Phenylamino)-7-((S)-Tetrahydrofuran-3-Yloxy)-Quinazolin-6-Ylcarbamoyl]-Methyl}-Phosphonate. Grades: 95%. CAS No. 618061-76-0. Molecular formula: C24H27ClFN4O6P. Mole weight: 552.92.
Afatinib impurity 69
Afatinib impurity 69. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-4-chloro-3-hydroxybutanoic acid. CAS No. 106941-19-9. Molecular formula: C4H7ClO3. Mole weight: 138.55. Catalog: APB106941199.
Afatinib Impurity A
An analogue of Afatinib. Synonyms: 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)?-6-nitro-7-[[(3R)?-tetrahydro-3-furanyl]?oxy]?-. Grades: > 95%. CAS No. 402855-07-6. Molecular formula: C18H14ClFN4O4. Mole weight: 404.79.
Afatinib Impurity AFT-8
An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: Afatinib Impurity QJJ; N-[4-((3-Chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)-3-hydroxybutenamide; Butanamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-3-hydroxy-. Grades: ≥95%. CAS No. 2323570-72-3. Molecular formula: C24H27ClFN5O4. Mole weight: 503.95.
Afatinib Impurity B
An analogue of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: Afatinib-des(4-dimethylamino-2-en-1-oxo)butyl; N4-(3-Chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]-4,6-quinazolinediamine; (S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine. Grades: > 95%. CAS No. 314771-76-1. Molecular formula: C18H16ClFN4O2. Mole weight: 374.81.
Afatinib Impurity C
An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)?amino]?-7-[[(3R)?-tetrahydro-3-furanyl]?oxy]?-6-quinazolinyl]?-4-(dimethylamino)?-, (2E)?-. Grades: > 95%. CAS No. 945553-91-3. Molecular formula: C24H25ClFN5O3. Mole weight: 485.95.
Afatinib Impurity CSEJXA
An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: (S)-N1-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-N2,N2-dimethyloxalamide (Afatinib Impurity; (S)-N1-(4-((3-CHLORO-4-FLUOROPHENYL)AMINO)-7-((TETRAHYDROFURAN-3-YL)OXY)QUINAZOLIN-6-YL)-N2,N2-DIMETHYLOXALAMIDE; Afatinib Impurity CSEJXA; CS-0164258; E82032; (S)-N1-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-N2,N2-dimethyloxalamide (Afatinib Impurity pound(c). Grades: ≥95%. CAS No. 2223677-66-3. Molecular formula: C22H21ClFN5O4. Mole weight: 473.88.
Afatinib Impurity CSZ
An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Grades: ≥95%. Molecular formula: C22H20ClFN4O5. Mole weight: 474.87.
Afatinib impurity D
Afatinib impurity D. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S,Z)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide; Z-Afatinib. CAS No. 1680184-59-1. Molecular formula: C24H25ClFN5O3. Mole weight: 485.94. Catalog: APB1680184591.
Afatinib Impurity D
An analogue of Afatinib, a medication indicated for the treatment of non-small cell lung carcinoma (NSCLC). Synonyms: (2Z)-Afatinib; Z-Afatinib; (S,Z)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide. Grades: > 95%. CAS No. 1680184-59-1. Molecular formula: C24H25ClFN5O3. Mole weight: 485.95.
Afatinib Impurity ESS
An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Grades: ≥95%. Molecular formula: C30H34ClFN6O4. Mole weight: 597.09.
Afatinib Impurity I
An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: Bromo-Afatinib; (S,E)-4-bromo-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide. Grades: ≥95%. CAS No. 1637254-93-3. Molecular formula: C22H19BrClFN4O3. Mole weight: 521.78.
Afatinib Impurity J
An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: (2E)-N-[3,4-Dihydro-4-oxo-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide; (S,E)-4-(DIMETHYLAMINO)-N-(4-HYDROXY-7-((TETRAHYDROFURAN-3-YL)OXY)QUINAZOLIN-6-YL)BUT-2-ENAMIDE; (S,e)-4-(dimethylamino)-N-(4-oxo-7-((tetrahydrofuran-3-yl)oxy)-3,4-dihydroquinazolin-6-yl)but-2-enamide; Afatinib Impurity J; SCHEMBL17352060; SCHEMBL17352063; GSUSIQVMAQBROU-PCAWENJQSA-N; CS-0164268; E82037; (S,E)-4-(Dimethylamino)-N-(4-hydroxy-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide (Afatinib Impurity). Grades: > 95%. CAS No. 1456696-14-2. Molecular formula: C18H22N4O4. Mole weight: 358.4.
Afatinib Impurity JXH
An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]formamide; Des(N,N-Dimethylprop-2-enyl-1-Amine) Afatinib. Grades: ≥95%. CAS No. 2223677-60-7. Molecular formula: C19H16ClFN4O3. Mole weight: 402.81.
Afatinib Impurity N-Oxide
An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: (S,E)-4-((4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)amino)-N,N-dimethyl-4-oxobut-2-en-1-amine oxide. Grades: ≥95%. CAS No. 2413212-11-8. Molecular formula: C24H25ClFN5O4. Mole weight: 501.94.
Afatinib Impurity O
An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: (S,E)-4-broMo-N-(4-((3-chloro-4-fluorophenyl)aMino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enaMide; (E)-4-bromo-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]but-2-enamide; Bromo-Afatinib; C22H19BrClFN4O3; AFATINIB IMPURITY O; SCHEMBL16398947; SCHEMBL16398952; IQJWAIKYBNTYPG-YUKKFKLSSA-N; CS-0164267; (2E)-4-Bromo-N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-2-butenamide; (S,E)-4-Bromo-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide (Afatinib Impurity). Grades: ≥95%. Molecular formula: C18H15FN4O4. Mole weight: 370.34.
Afatinib Impurity Q
An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Grades: ≥95%. Molecular formula: C14H7ClF2N4O2. Mole weight: 336.68.
Afatinib Impurity QA
An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Grades: ≥95%. Molecular formula: C18H16ClFN4O3. Mole weight: 390.80.
Afatinib Impurity SCl
An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: (S,E)-N-(4-((3,4-Dichlorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide. Grades: ≥95%. CAS No. 2223677-63-0. Molecular formula: C24H25Cl2N5O3. Mole weight: 502.39.
Afatinib Impurity SM2A
An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: 2-Butenamide, 4-(dimethylamino)-N,N-dimethyl-. Grades: ≥95%. CAS No. 1862246-17-0. Molecular formula: C8H16N2O. Mole weight: 156.23.
Afatinib Impurity WZYGNH2
An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Grades: ≥95%. Molecular formula: C18H16ClFN4O2. Mole weight: 370.80.
Afatinib Impurity WZYGNO2
An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Grades: ≥95%. Molecular formula: C18H14ClFN4O4. Mole weight: 404.78.
AFB-guanine
AFB-guanine. Group: Biochemicals. Alternative Names: (6aS, 8R, 9R, 9aR)-8-(2-Amino-1, 6-dihydro-6-oxo-7H-purin-7-yl)-2, 3, 6a, 8, 9, 9a-hexahydro-9-hydroxy-4-methoxy-cyclopenta[c]furo[3', 2':4, 5]furo[2, 3-h][1]benzopyran-1, 11-dione. Grades: Highly Purified. CAS No. 63425-04-7. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C22H17N5O8. US Biological Life Sciences.
Worldwide
AFB-Guanine Acetic Acid Salt
Acetic acid of a guanine adduct of Aflatoxin B1. Synonyms: (6aS,8R,9R,9aR)-8-(2-Amino-1,6-dihydro-6-oxo-7H-purin-7-yl)-2,3,6a,8,9,9a-hexahydro-9-hydroxy-4-methoxy-cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione Acetic Acid. Grades: 95%. Molecular formula: C24H21N5O10. Mole weight: 539.45.
AFC
AFC. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7-Amino-4-trifluoromethylcoumarin. Product Category: Other Fluorophores. CAS No. 53518-15-3. Molecular formula: C10H6F3NO2. Mole weight: 229.15. Product ID: ACM53518153. Alfa Chemistry ISO 9001:2015 Certified.
AF-DX 116
AF-DX 116 has been found to be a selective mAChR M2 antagonist. Synonyms: Otenzepad; AF-DX 116; AF-DX-116; AF-DX116; 11-[[2-[(Diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one. Grades: ≥98% by HPLC. CAS No. 102394-31-0. Molecular formula: C24H31N5O2. Mole weight: 421.54.
Selective presynaptic muscarinic receptor M2 antagonist with cardioselectivity. Exhibits antiarrhythmic effects in vivo, also shown to reverse the memory impairment effect of insulin in a mouse model. Group: Biochemicals. Grades: Highly Purified. CAS No. 102394-31-0. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences.
Worldwide
AF-DX 384
AF-DX 384. Group: Biochemicals. Grades: Purified. CAS No. 118290-26-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
AF-DX 384
AF-DX 384 is a selective antagonist of M2 and M4 muscarinic acetylcholine receptors ( K i s =6.03 and 10 nM, respectively) [1]. AF-DX 384 reverses deficits in novel object recognition and passive avoidance in aged rats, as well as in young rats with impairments induced by scopolamine [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 118290-26-9. Pack Sizes: 5 mg. Product ID: HY-107652.
AF-DX 384
AF-DX 384 has been found to be a mAChR M2/M4 selective antagonist. Uses: Parasympatholytics. Synonyms: N-[2-[2-[(Dipropylamino)methyl]-1-piperidinyl]ethyl]-5,6-dihydro-6-oxo-11H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide. Grades: ≥98% by HPLC. CAS No. 118290-26-9. Molecular formula: C27H38N6O2. Mole weight: 478.64.
Afegostat is a pharmacological chaperone, which specifically and reversibly binds acid-β-glucosidase ( GCase ) in the endoplasmic reticulum (ER) with high affinity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: D-Isofagomine; Isofagomine. CAS No. 169105-89-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-14829.
Afegostat D-Tartrate
Afegostat D-Tartrate is a pharmacological chaperone, which specifically and reversibly binds acid-β-glucosidase ( GCase ) in the endoplasmic reticulum (ER) with high affinity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: D-Isofagomine D-Tartrate; Isofagomine D-Tartrate. CAS No. 957230-65-8. Pack Sizes: 1 mg. Product ID: HY-14829E.
Afe I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA (BamHI-digest) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme more than 80% of dna pbr322 fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. AGC↑GCT TCG↓CGA. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer B, BSA. Storage: -20°C. Form: Liquid. Source: An E.coli strain that carries the cloned Afe I gene from Alcaligenes faecalis T2774. Pack: 10 mM Tris-HCl (pH 7.6); 50 mM NaCl; 0.1 mM EDTA; 1 mM DTT; 200 μg/ml BSA; 50% glycerol. Cat No: RE-1014EN.
Afelimomab
Afelimomab (MAK 195F) is an anti-tumor necrosis factor F(ab')2 monoclonal antibody fragment. Afelimomab can be used for the research of sepsis [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MAK 195F. CAS No. 156227-98-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99425.
AFG206
AFG206 is the novel first-generation "type II" FLT3 inhibitor. Synonyms: AFG-206; AFG 206. Grades: >98%. CAS No. 630122-37-1. Molecular formula: C20H19N3O2. Mole weight: 333.38.
AFG210
AFG210 is a novel first-generation "type II" FLT3 inhibitor. Synonyms: AFG 210; AFG-210; 1-(3-(trifluoromethyl)phenyl)-3-(4-(pyridin-4-yloxy)phenyl)urea. Grades: >98%. CAS No. 228400-22-4. Molecular formula: C19H14F3N3O2. Mole weight: 373.33.
Aficamten
Aficamten (CK-274) is a potent cardiac myosin inhibitor with an IC 50 of 1.4 μM. Aficamten can be used for the research of hypertrophic cardiomyopathy (HCM) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CK-274; CK-3773274. CAS No. 2364554-48-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139465.
Aficamten
Aficamten, also known as CK-3773274 and CK-274, is a Next-Generation Cardiac Myosin Inhibitor for the Treatment of Hypertrophic Cardiomyopathy. Aficamten was designed to provide a predicted human half-life (t1/2) appropriate for once a day (qd) dosing, to reach steady state within two weeks, to have no substantial cytochrome P450 induction or inhibition, and to have a wide therapeutic window in vivo with a clear pharmacokinetic/pharmacodynamic relationship. In a phase I clinical trial, aficamten demonstrated a human t1/2 similar to predictions and was able to reach steady state concentration within the desired two-week window. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CK-3773274; CK3773274; CK 3773274; CK-274; CK274; CK 274. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2364554-48-1. Molecular formula: C18H19N5O2. Mole weight: 337.38. Purity: >98%. IUPACName: N-[(1R)-5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl]-1-methyl-1H-pyrazole-4-carboxamide. Canonical SMILES: O=C(C1=CN(C)N=C1)N[C@@H]2CCC3=C2C=CC(C4=NOC(CC)=N4)=C3. Product ID: ACM2364554481. Alfa Chemistry ISO 9001:2015 Certified.
Afimetoran
Afimetoran (BMS-986256) is an orally active, selective, and highly bioavailable TLR7/8 antagonist. Afimetoran (BMS-986256) can inhibit TLR7/8 activation of the NF-κB pathway and reverse TLR7 mediated resistance to steroid induced apoptosis in plasma cell like dendritic cells (pDCs). Afimetoran (BMS-986256) can be used for research on inflammation and autoimmune diseases (systemic lupus erythematosus) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-986256. CAS No. 2171019-55-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139567.
Afimkibart
Afimkibart (PF-06480605) is a human IgG1 monoclonal antibody targeting tumor necrosis factor-like ligand 1A (TL1A). Afimkibart can be used in the research of inflammatory bowel disease[1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: PF-06480605; RVT-3101. CAS No. 2911580-96-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990876.
Afimoxifene
Afimoxifene (4-hydroxytamoxifen) is a selective estrogen receptor modulator which is the active metabolite of tamoxifen. Afimoxifene is a transdermal gel formulation and is being developed by Ascend Therapeutics, Inc. under the trademark TamoGel. Afimoxifene has completed a phase II clinical trial for the treatment of cyclical mastalgia. Uses: Estrogen antagonists. Synonyms: (E/Z)-4-Hydroxytamoxifen; 4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol; TamoGel; Phenol, 4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-. Grades: ≥95%. CAS No. 68392-35-8. Molecular formula: C26H29NO2. Mole weight: 387.51.
Aflastatin A
It is produced by the strain of Streptomyces sp. MRI 142. Aflatoxin A has anti-Gram-positive bacteria, Pyricularia oryzae and yeast activity (MIC is 0.19-0.39 μg/mL), and inhibits the growth of adenocarcinoma 755 (1.0 mg/kg reduces tumor growth by 75% the above). Synonyms: 2,4-Pyrrolidinedione, 1, 5-dimethyl-3-(1, 8, 9, 11, 13, 15, 17, 19, 21, 23, 25, 27, 28, 29, 30, 31-hexadecahydroxy-2, 4, 6, 10, 12, 14, 18, 20-octamethyl-32-(tetrahydro-3, 4, 5, 6-tetrahydroxy-6-(2-hydroxyundecyl)-2H-pyran-2-yl)-2-dotriacontenylidene)-; LS-137668. Grades: ≥ 95%. CAS No. 179729-59-0. Molecular formula: C62H115NO24. Mole weight: 1258.56.
Aflatoxicol
Aflatoxin (Aflatoxin R0) is a metabolite of aflatoxin B1 produced from Rhizopus spp [1] , and is mutagenic and carcinogenic mycotoxin [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Aflatoxin R0. CAS No. 29611-03-8. Pack Sizes: 1 mg. Product ID: HY-N6695.
Aflatoxicol
The 2 ppm acetonitrile solution of aflatoxicol, a metabolite of aflatoxin, could be commonly used as a standard solution. Uses: Only to be used as a reference standard in analytical laboratories. Synonyms: Aflatoxin Ro; (1S-(1alpha, 6abeta, 9abeta))-2, 3, 6a, 9a-Tetrahydro-1-hydroxy-4-methoxycyclopenta(c)furo(3', 2':4, 5)furo(2, 3-h)(1)benzopyran-11(1H)-one; Cyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-11(1H)-one, 2,3,6a,9a-tetrahydro-1-hydroxy-4-methoxy-, (1S,6aR,9aS)-; AFL. Grades: ≥98%. CAS No. 29611-03-8. Molecular formula: C17H14O6. Mole weight: 314.29.
AFLATOXICOL I NATURAL ISOMER VACUUM DRIED
AFLATOXICOL I NATURAL ISOMER VACUUM DRIED. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (1R,6aS,9aS)-1-Hydroxy-4-methoxy-2,3,6a,9a-tetrahydrocyclopenta[c]furo[3,2:4,5]furo[2,3-h]chromen-11(1H)-one. Product Category: Heterocyclic Organic Compound. CAS No. 29611-03-8. Molecular formula: C17H14O6. Mole weight: 314.289. Purity: 0.96. IUPACName: Aflatoxicol A. Density: 1.56g/cm³. Product ID: ACM29611038. Alfa Chemistry ISO 9001:2015 Certified.
Aflatoxin B1-[13C17]
Aflatoxin B1-[13C17] is the labelled analogue of Aflatoxin B1, which is an aflatoxin produced by Aspergillus flavus and A. parasiticus. Synonyms: Aflatoxin B1-13C17. Grades: 95% atom 13C. CAS No. 1217449-45-0. Molecular formula: [13C]17H12O6. Mole weight: 329.15.
Aflatoxin B1 aldehyde reductase member 2 from Human, Recombinant
Aflatoxin B1 aldehyde reductase member 2 catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Has NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2-nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). Can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro). Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen. Group: Enzymes. Synonyms: AFB1 aldehyde reductase 1; AFB1-AR 1; Aldoketoreductase 7; Succinic semialdehyde reductase. Enzyme Commission Number: EC 1.1.1.n11. AKR7A2. Mole weight: 39588.9 Da. Source: Human. AFB1 aldehyde reductase 1; AFB1-AR 1; Aldoketoreductase 7; Succinic semialdehyde reductase; EC 1.1.1.n11; AKR7A2; Aflatoxin B1 aldehyde reductase member 2. Cat No: NATE-1196.
Aflatoxin B2
Aflatoxins B1, B2, G1, G2 as secondary metabolites of fungal species such as Aspergillus flavus or Aspergillus parasiticus growing on a variety of foods (peanuts, nuts, spices, cereals). Aflatoxins are a group of very carcinogenic mycotoxins with hepatotoxic effects. Group: Biochemicals. Alternative Names: (6aR, 9aS) -2, 3, 6a, 8, 9, 9a-Hexahydro-4-methoxycyclopenta [c]furo [3, 2: 4, 5]furo [2, 3-h] [1]benzopyran-1, 11-dione; Dihydroaflatoxin B1; Dihydroaflatoxine B1. Grades: Highly Purified. CAS No. 7220-81-7. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences.
Worldwide
Aflatoxin (BSA)
Aflatoxins belong to the class of mycotoxins. Toxic fungal metabolite and carcinogen. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
aflatoxin B synthase
A heme-thiolate (P-450) enzyme. Isolated from the mold Aspergillus parasiticus. Group: Enzymes. Synonyms: ordA (gene name); 8-O-methylsterigmatocystin,NADPH:O2 oxidoreductase (aflatoxin-B forming). Enzyme Commission Number: EC 1.14.13.175. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0773; aflatoxin B synthase; EC 1.14.13.175; ordA (gene name); 8-O-methylsterigmatocystin,NADPH:O2 oxidoreductase (aflatoxin-B forming). Cat No: EXWM-0773.
Aflatoxin G1
Aflatoxin G1 is the major analogue of the green fluorescent family of bisfuranocoumarin mycotoxins produced by Aspergillus flavus and related species. Alfatoxins are one of the most potent mycotoxins known but are in fact "pre-toxins" requiring metabolic activation to the toxic principle. Aflatoxins are found widely in nature in trace amounts particularly grains and nuts. The toxicity of these metabolites was first recognised in the 1950s and their structures elucidated in 1963. Aflatoxins have been extensively reviewed. Source:Aflatoxin G1 from Aspergillus flavus. Group: Biochemicals. Alternative Names: (7aR, 10aS)-3, 4, 7a, 10a-Tetrahydro-5-methoxy-1H, 12H-furo[3, 2:4, 5]furo[2, 3-h]pyrano[3, 4-c][1]benzopyran-1, 12-dione. Grades: Highly Purified. CAS No. 1165-39-5. Pack Sizes: 1mg, 5mg. Molecular Formula: C17H12O7, Molecular Weight: ~328.3. US Biological Life Sciences.
Worldwide
Aflatoxin G1
from Aspergillus flavus. Group: Fluorescence/luminescence spectroscopymycotoxinsmycotoxinschiral molecules. Alternative Names: 1H,12H-Furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c][1]benzopyran-1,12-dione, 3,4,7a,10a-tetrahydro-5-methoxy-, (7aR-cis)-, (7aR,10aS)-3,4,7a,10a-Tetrahydro-5-methoxy-1H,12H-furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c][1]benzopyran-1,12-dione, Aflatoxin G1 (7CI),1H,12H-Furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c][1]benzopyran-1,12-dione, 3,4,7a,10a-tetrahydro-5-methoxy-, (7aR,10aS)-.
Aflatoxin G2
Aflatoxins B1, B2, G1, G2 as secondary metabolites of fungal species such as Aspergillus flavus or Aspergillus parasiticus growing on a variety of foods (peanuts, nuts, spices, cereals). Aflatoxins are a group of very carcinogenic mycotoxins with hepatotoxic effects. Group: Biochemicals. Alternative Names: (7aR, 10aS)-3, 4, 7a, 9, 10, 10a-Hexahydro-5-methoxy-1H, 12H-furo[3', 2':4, 5]furo[2, 3-h]pyrano[3, 4-c][1]benzopyran-1, 12-dione. Grades: Highly Purified. CAS No. 7241-98-7. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Aflatoxin M1
An Aspergillus flavus metabolite. Aflatoxin M1 in milk as a secondary metabolite of the Aflatoxin B1 formed in moldy forages. It is cancerogenic, hepatotoxic, and immunosuppressive in animals and man. Group: Biochemicals. Alternative Names: (6aR, 9aR)-2, 3, 6a, 9a-Tetrahydro-9a-hydroxy-4-methoxy-cyclopenta[c]furo[3, 2:4, 5]furo[2, 3-h][1]benzopyran-1, 11-dione; AFM1. Grades: Highly Purified. CAS No. 6795-23-9. Pack Sizes: 250ug. US Biological Life Sciences.
Worldwide
Aflatoxin M1
It is produced by the strain of Aspergillus flavus, Asp. parasiticus. The compound of aflatoxin has the activity of anti-gram-positive bacteria, inhibits cell mitosis, has the effect of liver necrosis and carcinogenesis, and is a mycotoxin which contaminates food. Synonyms: AFLATOXIN M1; 4-Hydroxyaflatoxin B1; 3020O28I3; CCRIS 15; (6aR, 9aR)-9a-hydroxy-4-methoxy-2, 3, 6a, 9a-tetrahydrocyclopenta[c]furo[3', 2':4, 5]furo[2, 3-h]chromene-1, 11-dione; (6aR-cis)-2, 3, 6a, 9a-tetrahydro-9a-hydroxy-4-methoxycyclopenta[c]furo[3', 2':4, 5]furo[2, 3-h][1]benzopyran-1, 11-dione; CHEBI:78576; Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione,2,3,6a,9a-tetrahydro-9a-hydroxy-4-methoxy-,(6ar,9ar)-. Grades: ≥95%. CAS No. 6795-23-9. Molecular formula: C17H12O7. Mole weight: 328.27.
Aflatoxin Q1
Aflatoxin Q1 is a metabolite of Aflatoxin B1. It is created in human body as a in-vivo detoxification process of Aflatoxin B1. Uses: A metabolite of aflatoxin b1; a hepatocarcinogen in many animal models and probably a human carcinogen. it is produced by the predominant forms of cytochrome p 450 enzymes responsible for the biotransformation of afb1. it shows potential predictive value. Synonyms: Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-3-hydroxy-4-methoxy-, (3S,6aR,9aS)-; Cyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-3-hydroxy-4-methoxy-, (3S-(3-alpha,6a-alpha,9a-alpha))-; (3S, 6aR, 9aS)-3-hydroxy-4-methoxy-2, 3, 6a, 9a-tetrahydrocyclopenta[c]furo[3', 2':4, 5]furo[2, 3-h]chromene-1, 11-dione. Grades: ≥98%. CAS No. 52819-96-2. Molecular formula: C17H12O7. Mole weight: 328.27.
Aflatrem
Aflatrem is the secondary metabolite of Aspergillus flavus. It is able to induce degeneration of neuronal processes in hippocampal neurotransmitter systems at low dose. It potentiates the gamma-aminobutyric acid (GABA)-induced chloride current. It is a tremorgenic mycotoxin with acute neurotoxic effect. Synonyms: 4H-3,15a-Epoxy-1-benzoxepino[6',7':6,7]indeno[1,2-b]indol-4-one, 9-(1,1-dimethyl-2-propenyl)-2,3,5b,6,7,7a,8,13,13b,13c,14,15-dodecahydro-5b-hydroxy-2,2,13b,13c-tetramethyl-, (3R,5bS,7aS,13bS,13cR,15aS)-; 9-(1, 1-Dimethyl-2-propenyl)-2, 3, 5b, 6, 7, 7aα, 8, 13, 13b, 13c, 14, 15-dodecahydro-5bβ-hydroxy-2, 2, 13bβ, 13cα-tetramethyl-4H-3β, 15aβ-epoxy-1-benzoxepino[6', 7':6, 7]indeno[1, 2-b]indol-4-one; α,α-dimethylallylpaspalinine. Grades: 98.0%. CAS No. 70553-75-2. Molecular formula: C32H39NO4. Mole weight: 501.66.
Aflavarin
Aflavarin is a metabolite of the Sclerotia of Aspergillus flavus displaying anti-insectan activity against the fungivorous beetle Carpopbilus bemipterus. Synonyms: (3,8'-Bi-2H-1-benzopyran)-2,2'-dione, 5-(hydroxymethyl)-4,4',7,7'-tetramethoxy-5'-methyl-, (-)-; (-)-5-(Hydroxymethyl)-4,4',7,7'-tetramethoxy-5'-methyl[3,8'-bi-2H-1-benzopyran]-2,2'-dione. Grades: 98.0%. CAS No. 144429-67-4. Molecular formula: C24H22O9. Mole weight: 454.43.
Aflavazole
Aflavazole is a metabolite of the sclerotia of Aspergillus flavus. It shows antifeedant activity against the fungivorous beetle Carpophilus hemipterus remarkably. Synonyms: (1R,4S,4aS,13dS,14R,16R,16aS)-1,2,3,4,5,6,9,13d,14,15,16,16a-Dodecahydro-1,7,14,16a-tetramethylphenanthro[2,1-c]carbazole-4,16-diol; (+)-Aflavazole; Benzo(4a,5)naphtho(2,1-c)carbazole-4,16-diol, 1,2,3,4,5,6,9,13d,14,15,16,16a-dodecahydro-1,7,14,16a-tetramethyl-, (1alpha, 4alpha, 4aS*, 13dbeta, 14alpha, 16beta, 16aalpha)-(+)-; Benzo(4a,5)naphtho(2,1-c)carbazole-4,16-diol,1,2,3,4,5,6,9,13d,14,15,16,16a-dodecahydro-1,7,16a-tetramethyl-, (1R,4S,4aS,13dS,14R,16R,16aS)-rel-(+)-. Grades: 97.5%. CAS No. 2043963-70-6. Molecular formula: C28H35NO2. Mole weight: 417.58.
Aflibercept
Aflibercept is a recombinant fusion protein and acts as a VEGF inhibitor. Aflibercept is used for the treatment of wet macular degeneration and metastatic colorectal cancer. Synonyms: Eylea. CAS No. 862111-32-8. Molecular formula: C4318H6788N1164O1304S32. Mole weight: 96898.57.
Aflibercept
Aflibercept (VEGF Trap) is a soluble decoy VEGFR constructed by fusing the Ig domains of VEGFR 1 and VEGFR 2 with the Fc region of human IgG1. Aflibercept inhibits VEGF signaling by reducing VEGF-regulated processes. Aflibercept can be used for thr research of age-related macular degeneration (AMD) and cardiovascular disease [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: VEGF Trap; VEGF-TRAPR1R2; VEGF-trapR1. CAS No. 862111-32-8. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-108801.
Aflibercept (VEGF Trap)
Aflibercept (VEGF Trap) is a soluble decoy VEGFR constructed by fusing the Ig domains of VEGFR 1 and VEGFR 2 with the Fc region of human IgG1. Aflibercept inhibits VEGF signaling by reducing VEGF-regulated processes. Aflibercept can be used for thr research of age-related macular degeneration (AMD) and cardiovascular disease [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 862111-32-8. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-108801A.
Afloqualone
Afloqualone is a agonist of GABA receptor has sedative and muscle-relaxant effects. Uses: A agonist of gaba receptor. Synonyms: HQ-495; HQ495; HQ 495. Afloqualone; 6-amino-2-(fluoromethyl)-3-(2-methylphenyl)quinazolin-4-one. Grades: ≥98%. CAS No. 56287-74-2. Molecular formula: C16H14FN3O. Mole weight: 283.3.
Afloqualone
Afloqualone (HQ-495) is an orally active central muscle relaxant and antivertiginous agent that can increase the sensitivity of GABA receptors in neurons of the lateral vestibular nucleus. Afloqualone (HQ-495) can be used in the research of low back pain and neck-arm-shoulder syndrome [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HQ-495. CAS No. 56287-74-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1833.
a-Fluoro-b-alanine
a-Fluoro-b-alanine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
A stable isotope analogue of the catabolism of the anti-cancer drug 5-Flurouracil. Group: Biochemicals. Alternative Names: (2R)-3-Amino-2-fluoropropanoic Acid-13C3. Grades: Highly Purified. CAS No. 1246819-54-4. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
a-Fluorophenylacetonitrile
a-Fluorophenylacetonitrile. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-FLUOROBENZYL CYANIDE 97%;Jrd-0527. Product Category: Heterocyclic Organic Compound. CAS No. 10036-43-8. Molecular formula: C8H6NF. Mole weight: 135.14. Product ID: ACM10036438. Alfa Chemistry ISO 9001:2015 Certified. Categories: 501-00-8.
AFM24
AFM24 is a bispecific antibody with a TandAb structure expressed in CHO, targeting EGFR&Fc-gamma-RIIIA. AFM24 contains a huIgG1-SCFV heavy chain and a ? light chain, with a predicted molecular weight (MW) of 74.5 kDa. The isotype control for AFM24 can refer to Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990314.