A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Adenosine, N-benzoyl-3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-2-propen-1-yl-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is an exceptional compound used in the research of formidable malignancies, such as lymphoma and leukemia. Its utilization in the pursuit of innovative antiviral therapeutics that specifically target RNA viruses denotes its indispensable role. Synonyms: ( (2S, 3R, 4R, 5R) -4- (allyloxy) -5- (6-benzamido-9H-purin-9-yl) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299282-94-1. Molecular formula: C49H55N8O6P. Mole weight: 882.98.
Adenosine, N-benzoyl-3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-methyl-, 5'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI) is a complex chemical entity employed in the synthesis of oligonucleotides targeting viral infections and various cancers. The versatility of this remarkable molecule extends beyond biomedical research and treatment; it has the potential to alter genetic sequences, thereby opening new therapeutic avenues for myriad hitherto enigmatic human ailments. Its designation as a universally valuable synthetic building block in both academic and clinical milieus underscores its indispensability in biomedicine. Synonyms: ( (2S, 3R, 4R, 5R) -5- (6-benzamido-9H-purin-9-yl) -4-methoxy-3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 329773-22-0. Molecular formula: C47H53N8O6P. Mole weight: 856.95.
Adenosine (N-Bz)
Adenosine (N-Bz) is an essential biomedical compound widely employed in the research of numerous cardiovascular disorders, comprising arrhythmias and angina pectoris. It can interact with adenosine receptors. Grades: ≥ 98% by HPLC. Molecular formula: C17H17N5O5. Mole weight: 371.35.
Adenosine (N-PAC)
Adenosine (N-PAC), a pharmaceutical-grade compound, is a multifaceted agent, possessing the ability to treat various cardiovascular disorders: arrhythmias, angina, and hypertension. Mechanistically, its mechanism of action lies in selectively inducing the activation of specific receptors in the heart. Its downstream effects manifest as a non-negligible reduction in heart rate, accompanied by a reciprocal elevation in blood flow. Additionally, Adenosine (N-PAC) has utility in the diagnosis and treatment of certain types of irregular heartbeats, serving as an invaluable tool in the evaluation of blood circulation in cardiac imaging. Grades: ≥ 98% by HPLC. Molecular formula: C18H19N5O6. Mole weight: 401.37.
adenosine nucleosidase
Also acts on adenosine N-oxide. Group: Enzymes. Synonyms: adenosinase; N-ribosyladenine ribohydrolase; adenosine hydrolase; ANase. Enzyme Commission Number: EC 3.2.2.7. CAS No. 9075-41-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3989; adenosine nucleosidase; EC 3.2.2.7; 9075-41-6; adenosinase; N-ribosyladenine ribohydrolase; adenosine hydrolase; ANase. Cat No: EXWM-3989.
Adenosine phosphate
Adenosine phosphate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 61-19-8. Molecular Formula: C10H14N5O7P. Mole Weight: 347.22. Catalog: APB61198.
adenosine-phosphate deaminase
Acts on AMP, ADP, ATP, NAD+ and adenosine, in decreasing order of activity. The bacterial enzyme can also accept the deoxy derivatives. cf. EC 3.5.4.6, AMP deaminase. Group: Enzymes. Synonyms: adenylate deaminase; adenine nucleotide deaminase; adenosine (phosphate) deaminase. Enzyme Commission Number: EC 3.5.4.17. CAS No. 37289-20-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4543; adenosine-phosphate deaminase; EC 3.5.4.17; 37289-20-6; adenylate deaminase; adenine nucleotide deaminase; adenosine (phosphate) deaminase. Cat No: EXWM-4543.
A cell-permeable adenosine analog that acts a potent non-selective agonist of adenosine receptors (Ki = 14nM, 20nM, 2.4uM and 6.2nM for A1, A2A, A2B, A3, respectively). Increases intracellular cAMP production (EC50 = 3.1uM in A2B expressing CHO cells). Shown to increase glucagon release in a dose-dependent manner and inhibit insulin release at low concentrations. Although at higher concentration some insulin release is observed. Also, displays a wide range adenosine-dependent effects, such as blocking platelet aggregation and inhibiting DNA synthesis. When administered at reperfusion, it is shown reduce infarction and block the formation of the mitochondrial permeability transition pore by activating p70S6 kinase. Group: Biochemicals. Grades: Highly Purified. CAS No. 35920-39-9. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Adenosine receptor antagonist 2
Adenosine receptor antagonist 2 is an orally active A2a/A2b adenosine receptor antagonist with IC 50 s of 1 nM and 3 nM, respectively. Adenosine receptor antagonist 2 has anti-tumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2703054-47-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144064.
Adenosine receptor antagonist 3
Adenosine receptor antagonist 3 is a potent antagonist of adenosine receptor. Adenosine receptor antagonist 3 has the potential for the research of cancer disease (extracted from patent WO2019233994A1, compound 1) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2400864-80-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144419.
Adenosine receptor inhibitor 1
Adenosine receptor inhibitor 1 is a potent and selective adenosine receptor (AR) inhibitor with K i values of >1000, 68.5, >1000, >1000 nM for A 1 AR, A 2A AR, A 2B AR, A 3 AR, respectively. Adenosine receptor inhibitor 1 shows antinociceptive activity, anti-inflammatory effect and peripheral analgesic effect. Adenosine receptor inhibitor 1 has the potential for the research of cancer or neurodegenerative diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2550400-52-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-147907.
Adenosine (Standard)
Adenosine (Standard) is the analytical standard of Adenosine. This product is intended for research and analytical applications. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 58-61-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0228R.
adenosine-tetraphosphatase
Also acts on inosine tetraphosphate and tripolyphosphate but shows little or no activity with other nucleotides or polyphosphates. Group: Enzymes. Enzyme Commission Number: EC 3.6.1.14. CAS No. 37289-26-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4598; adenosine-tetraphosphatase; EC 3.6.1.14; 37289-26-2. Cat No: EXWM-4598.
adenosinetriphosphatase
Many enzymes previously listed under this number are now listed separately under EC 3.6.3 and EC 3.6.4. Group: Enzymes. Synonyms: adenylpyrophosphatase; ATP monophosphatase; triphosphatase; ATPase (ambiguous); SV40 T-antigen; adenosine 5'-triphosphatase; ATP hydrolase; complex V (mitochondrial electron transport); (Ca2+ + Mg2+)-ATPase; HCO3--ATPase; adenosine triphosphatase. Enzyme Commission Number: EC 3.6.1.3. CAS No. 9000-83-3. Adenosine 5'-Triphosphatase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4614; adenosinetriphosphatase; EC 3.6.1.3; 9000-83-3; adenylpyrophosphatase; ATP monophosphatase; triphosphatase; ATPase (ambiguous); SV40 T-antigen; adenosine 5'-triphosphatase; ATP hydrolase; complex V (mitochondrial electron transport); (Ca2+ + Mg2+)-ATPase; HCO3--ATPase; adenosine triphosphatase. Cat No: EXWM-4614.
Adenosine triphosphate
ATP disodium hydrate. CAS No. 56-65-5. Product ID: 2-08486. Molecular formula: C10H14N5O13P3Na2 · xH2O. Mole weight: 551.15.
Adenosine Triphosphate, Disodium Salt (ATP-2Na)
UV Spectral Analysis: Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10g. US Biological Life Sciences.
Worldwide
adenosyl-chloride synthase
This enzyme, isolated from the marine bacterium Salinispora tropica, catalyses an early step in the pathway leading to biosynthesis of the proteosome inhibitor salinosporamide A. The enzyme is very similar to EC 2.5.1.63, adenosyl-fluoride synthase, but does not accept fluoride. Group: Enzymes. Synonyms: chlorinase; 5'-chloro-5'-deoxyadenosine synthase. Enzyme Commission Number: EC 2.5.1.94. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2833; adenosyl-chloride synthase; EC 2.5.1.94; chlorinase; 5'-chloro-5'-deoxyadenosine synthase. Cat No: EXWM-2833.
Adenosylcobalamin
Adenosylcobalamin (Coenzyme B12;Cobamamide;AdoCbl) is an active form of Vitamin B 12 which is a cofactor for methylmalonyl CoA mutase [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Coenzyme B12; Cobamamide; AdoCbl. CAS No. 13870-90-1. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-112790.
adenosylcobalamin/α-ribazole phosphatase
This enzyme catalyses the last step in the anaerobic (early cobalt insertion) pathway of adenosylcobalamin biosynthesis, characterized in Salmonella enterica.It also participates in a salvage pathway that recycles cobinamide into adenosylcobalamin. Group: Enzymes. Synonyms: CobC; adenosylcobalamin phosphatase; α-ribazole phosphatase. Enzyme Commission Number: EC 3.1.3.73. CAS No. 251991-06-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3678; adenosylcobalamin/α-ribazole phosphatase; EC 3.1.3.73; 251991-06-7; CobC; adenosylcobalamin phosphatase; α-ribazole phosphatase. Cat No: EXWM-3678.
adenosylcobinamide-GDP ribazoletransferase
In Salmonella typhimurium LT2, under anaerobic conditions, CobU (EC 2.7.7.62 and EC 2.7.1.156), CobT (EC 2.4.2.21), CobC (EC 3.1.3.73) and CobS (EC 2.7.8.26) catalyse reactions in the nucleotide loop assembly pathway, which convert adenosylcobinamide (AdoCbi) into adenosylcobalamin (AdoCbl). CobT and CobC are involved in 5,6-dimethylbenzimidazole activation whereby 5,6-dimethylbenzimidazole is converted to its riboside, α-ribazole. The second branch of the nucleotide loop assembly pathway is the cobinamide activation branch where AdoCbi or adenosylcobinamide-phosphate is converted to the activated intermediate AdoCbi-GDP by the bifunctional enzyme Cob U. CobS catalyses the final step in adenosylcobalamin biosynthesis, which is the condensation of AdoCbi-GDP with α-ribazole to yield adenosylcobalamin. Group: Enzymes. Synonyms: CobS; cobalamin synthase; cobalamin-5'-phosphate synthase; cobalamin (5'-phosphate) synthase. Enzyme Commission Number: EC 2.7.8.26. CAS No. 137672-85-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3325; adenosylcobinamide-GDP ribazoletransferase; EC 2.7.8.26; 137672-85-6; CobS; cobalamin synthase; cobalamin-5'-phosphate synthase; cobalamin (5'-phosphate) synthase. Cat No: EXWM-3325.
adenosylcobinamide hydrolase
Involved in the salvage pathway of cobinamide in archaea. Archaea convert adenosylcobinamide (AdoCbi) into adenosylcobinamide phosphate (AdoCbi-P) in two steps. First, the amidohydrolase activity of CbiZ cleaves off the aminopropanol moiety of AdoCbi yielding adenosylcobyric acid (AdoCby); second, AdoCby is converted into AdoCbi-P by the action of EC 6.3.1.10, adenosylcobinamide-phosphate synthase (CbiB). Group: Enzymes. Synonyms: CbiZ; AdoCbi amidohydrolase. Enzyme Commission Number: EC 3.5.1.90. CAS No. 905988-16-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4482; adenosylcobinamide hydrolase; EC 3.5.1.90; 905988-16-1; CbiZ; AdoCbi amidohydrolase. Cat No: EXWM-4482.
adenosylcobinamide kinase
In Salmonella typhimurium LT2, under anaerobic conditions, CobU (EC 2.7.7.62 and EC 2.7.1.156), CobT (EC 2.4.2.21), CobC (EC 3.1.3.73) and CobS (EC 2.7.8.26) catalyse reactions in the nucleotide loop assembly pathway, which convert adenosylcobinamide (AdoCbi) into adenosylcobalamin (AdoCbl). CobT and CobC are involved in 5,6-dimethylbenzimidazole activation whereby 5,6-dimethylbenzimidazole is converted to its riboside, α-ribazole. The second branch of the nucleotide loop assembly pathway is the cobinamide (Cbi) activation branch where AdoCbi or adenosylcobinamide-phosphate is converted to the activated intermediate AdoCbi-GDP by Cob U. The final step in adenosylcobalamin ...erase activity is required for both assimilation of exogenous cobinamide and for de novo synthesis of adenosylcobalamin. Group: Enzymes. Synonyms: CobU; adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; AdoCbi kinase/AdoCbi-phosphate guanylyltransferase. Enzyme Commission Number: EC 2.7.1.156. CAS No. 169592-51-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2985; adenosylcobinamide kinase; EC 2.7.1.156; 169592-51-2; CobU; adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; AdoCbi kinase/AdoCbi-phosphate guanylyltransferase. Cat No: EXWM-2985.
adenosylcobinamide-phosphate guanylyltransferase
In Salmonella typhimurium LT2, under anaerobic conditions, CobU (EC 2.7.7.62 and EC 2.7.1.156), CobT (EC 2.4.2.21), CobC (EC 3.1.3.73) and CobS (EC 2.7.8.26) catalyse reactions in the nucleotide loop assembly pathway, which convert adenosylcobinamide (AdoCbi) into adenosylcobalamin (AdoCbl). CobT and CobC are involved in 5,6-dimethylbenzimidazole activation whereby 5,6-dimethylbenzimidazole is converted to its riboside, α-ribazole. The second branch of the nuclotide loop assembly pathway is the cobinamide (Cbi) activation branch where AdoCbi or adenosylcobinamide-phosphate is converted to the activated intermediate AdoCbi-GDP by the bifunctional enzyme Cob U. Th...s a two-stage reaction with formation of a CobU-GMP intermediate. Guanylylation takes place at histidine-46. Group: Enzymes. Synonyms: CobU; adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; AdoCbi kinase/AdoCbi-phosphate guanylyltransferase. Enzyme Commission Number: EC 2.7.7.62. CAS No. 169592-55-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3274; adenosylcobinamide-phosphate guanylyltransferase; EC 2.7.7.62; 169592-55-6; CobU; adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; AdoCbi kinase/AdoCbi-phosphate guanylyltransferas
adenosylcobinamide-phosphate synthase
One of the substrates for this reaction, (R)-1-aminopropan-2-yl phosphate, is produced by CobD (EC 4.1.1.81, threonine-phosphate decarboxylase). Group: Enzymes. Synonyms: CbiB. Enzyme Commission Number: EC 6.3.1.10. CAS No. 905988-16-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5713; adenosylcobinamide-phosphate synthase; EC 6.3.1.10; 905988-16-1; CbiB. Cat No: EXWM-5713.
Requires Mg2+. NH3 can act instead of glutamine. This enzyme catalyses the four-step amidation sequence from cobyrinic acid a,c-diamide to cobyric acid via the formation of cobyrinic acid triamide, tetraamide and pentaamide intermediates. Group: Enzymes. Synonyms: CobQ; cobyric acid synthase; 5'-deoxy-5'-adenosylcobyrinic-acid-a,c-diamide:L-glutamine amido-ligase; Ado-cobyric acid synthase [glutamine hydrolyzing]. Enzyme Commission Number: EC 6.3.5.10. CAS No. 137672-90-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5803; adenosylcobyric acid synthase (glutamine-hydrolysing); EC 6.3.5.10; 137672-90-3; CobQ; cobyric acid synthase; 5'-deoxy-5'-adenosylcobyrinic-acid-a,c-diamide:L-glutamine amido-ligase; Ado-cobyric acid synthase [glutamine hydrolyzing]. Cat No: EXWM-5803.
adenosyl-fluoride synthase
The fluorinase enzyme (EC 2.5.1.63, also known as adenosyl-fluoride synthase) catalyzes the reaction between fluoride ion and the co-factor S-adenosyl-L-methionine to generate L-methionine and 5'-fluoro-5'-deoxyadenosine, the first committed product of the fluorometabolite biosynthesis pathway. Group: Enzymes. Synonyms: fluorinase. Enzyme Commission Number: EC 2.5.1.63. CAS No. 438583-16-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2801; adenosyl-fluoride synthase; EC 2.5.1.63; 438583-16-5; fluorinase. Cat No: EXWM-2801.
adenosylhomocysteinase
The enzyme contains one tightly bound NAD+ per subunit. This appears to bring about a transient oxidation at C-3' of the 5'-deoxyadenosine residue, thus labilizing the thioether bond (for mechanism, click here), cf. EC 5.5.1.4, inositol-3-phosphate synthase. Group: Enzymes. Synonyms: S-adenosylhomocysteine synthase; S-adenosylhomocysteine hydrolase (ambiguous); adenosylhomocysteine hydrolase; S-adenosylhomocysteinase; SAHase; AdoHcyase. Enzyme Commission Number: EC 3.3.1.1. CAS No. 9025-54-1. AHCY. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3992; adenosylhomocysteinase; EC 3.3.1.1; 9025-54-1; S-adenosylhomocysteine synthase; S-adenosylhomocysteine hydrolase (ambiguous); adenosylhomocysteine hydrolase; S-adenosylhomocysteinase; SAHase; AdoHcyase. Cat No: EXWM-3992.
Adenosylhomocysteinase
Adenosylhomocysteinase (SAHH; AHCY) is a highly conserved enzyme. Adenosylhomocysteinase reversible catalyzes S-adenosylhomocysteine (SAH) to adenosine and L-homocysteine. The serum exosomal Adenosylhomocysteinase level can be used as a prognostic biomarker in HBV-LC patients [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: SAHH; AHCY. CAS No. 9025-54-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-149048.
Adenosylhomocysteine
Adenosylhomocysteine. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C14H20N6O5S. Mole Weight: 384.41. Catalog: APB06539.
Adenosylhomocysteinease from Human, Recombinant
S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Adenosylhomocysteinase is an enzyme that converts S-adenosylhomocysteine to homocysteine and adenosine. This enzyme catalyses the following chemical reaction: S-adenosyl-L-homocysteine + H2O<-> L-homocysteine + adenosine. The enzyme contains one tightly bound NAD+ per subunit. Group: Enzymes. Synonyms: Adenosylhomocysteinase; S-adenosylhomocysteine synthase; S-adenosylhomocysteine hydrolase; adenosylhomocysteine hydr. Enzyme Commission Number: EC 3.3.1.1. CAS No. 9025-54-1. AHCY. Mole weight: 47 kDa. Storage: -20°C. Form: Purified and lyophilized powder or Purified, solution in 50% glycerol. Source: Human. Adenosylhomocysteinase; S-adenosylhomocysteine synthase; S-adenosylhomocysteine hydrolase; adenosylhomocysteine hydrolase ambiguous; S-adenosylhomocysteinase; SAHase; AdoHcyase; EC 3.3.1.1; 9025-54-1; AHCY. Cat No: DIA-122.
adenosylhomocysteine nucleosidase
Also acts on S-methyl-5'-thioadenosineto give adenine and S-methyl-5-thioribose (cf. EC 3.2.2.16, methylthioadenosine nucleosidase). Group: Enzymes. Synonyms: S-adenosylhomocysteine hydrolase (ambiguous); S-adenosylhomocysteine nucleosidase; 5'-methyladenosine nucleosidase; S-adenosylhomocysteine/5'-methylthioadenosine nucleosidase; AdoHcy/MTA nucleosidase. Enzyme Commission Number: EC 3.2.2.9. CAS No. 9055-10-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3991; adenosylhomocysteine nucleosidase; EC 3.2.2.9; 9055-10-1; S-adenosylhomocysteine hydrolase (ambiguous); S-adenosylhomocysteine nucleosidase; 5'-methyladenosine nucleosidase; S-adenosylhomocysteine/5'-methylthioadenosine nucleosidase; AdoHcy/MTA nucleosidase. Cat No: EXWM-3991.
A pyridoxal 5'-phosphate enzyme. S-adenosylhomocysteine can also act as donor. Group: Enzymes. Synonyms: 7,8-diaminonanoate transaminase; 7,8-diaminononanoate transaminase; DAPA transaminase (ambiguous); 7,8-diaminopelargonic acid aminotransferase; DAPA aminotransferase (ambiguous); 7-keto-8-aminopelargonic acid; diaminopelargonate synthase; 7-keto-8-aminopelargonic acid aminotransferase. Enzyme Commission Number: EC 2.6.1.62. CAS No. 37259-71-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2903; adenosylmethionine-8-amino-7-oxononanoate transaminase; EC 2.6.1.62; 37259-71-5; 7,8-diaminonanoate transaminase; 7,8-diaminononanoate transaminase; DAPA transaminase (ambiguous); 7,8-diaminopelargonic acid aminotransferase; DAPA aminotransferase (ambiguous); 7-keto-8-aminopelargonic acid; diaminopelargonate synthase; 7-keto-8-aminopelargonic acid aminotransferase. Cat No: EXWM-2903.
adenosylmethionine cyclotransferase
This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is S-adenosyl-L-methionine alkyltransferase (cyclizing). This enzyme is also called adenosylmethioninase. Group: Enzymes. Synonyms: adenosylmethioninase. Enzyme Commission Number: EC 2.5.1.4. CAS No. 9030-34-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2776; adenosylmethionine cyclotransferase; EC 2.5.1.4; 9030-34-6; adenosylmethioninase. Cat No: EXWM-2776.
adenosylmethionine decarboxylase
The Escherichia coli enzyme contains a pyruvoyl group. Group: Enzymes. Synonyms: S-adenosylmethionine decarboxylase; S-adenosyl-L-methionine decarboxylase; S-adenosyl-L-methionine carboxy-lyase; S-adenosyl-L-methionine carboxy-lyase [(5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium-salt-forming]. Enzyme Commission Number: EC 4.1.1.50. CAS No. 9036-20-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4796; adenosylmethionine decarboxylase; EC 4.1.1.50; 9036-20-8; S-adenosylmethionine decarboxylase; S-adenosyl-L-methionine decarboxylase; S-adenosyl-L-methionine carboxy-lyase; S-adenosyl-L-methionine carboxy-lyase [(5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium-salt-forming]. Cat No: EXWM-4796.
adenosylmethionine hydrolase
Also hydrolyses S-methyl-L-methionine sulfonium salt to dimethyl sulfide and homoserine. Group: Enzymes. Synonyms: S-adenosylmethionine cleaving enzyme; methylmethionine-sulfonium-salt hydrolase; adenosylmethionine lyase. Enzyme Commission Number: EC 3.3.1.2. CAS No. 37288-62-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3993; adenosylmethionine hydrolase; EC 3.3.1.2; 37288-62-3; S-adenosylmethionine cleaving enzyme; methylmethionine-sulfonium-salt hydrolase; adenosylmethionine lyase. Cat No: EXWM-3993.
adenosyl methionine S
adenosyl methionine S. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C15H23N6O5S+. Mole Weight: 399.45. Catalog: APB06538.
A sulfonyl diphenyl ene -bis-dicyclohexyl aminoacetamide compound that acts as a potent and selective inhibitor against adenovirus cysteine proteinase AVP by targeting simultaneously AVP co-factor pVIc (GVQSLKRRRCF) N-terminal binding pocket (Ki = 150nM) and AVP-pVIc substrate-binding site (Ki = 400nM), blocking both AVP-pVIc active complex formation (IC50 = 140nM; [substrate] = 5uM & [pVIc] = 40uM) and catalytic activity (IC50 = 490nM; [substrate] = 5uM) without affecting trypsin or papain protease activity even at concentrations as high as 10uM. Group: Biochemicals. Grades: Purified. CAS No. 2907-88-2. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?S. US Biological Life Sciences.
Worldwide
adenylate cyclase
Also acts on dATP to form 3',5'-cyclic dAMP. Requires pyruvate. Activated by NAD+ in the presence of EC 2.4.2.31 NAD(P)+-arginine ADP-ribosyltransferase. Group: Enzymes. Synonyms: adenylylcyclase; adenyl cyclase; 3',5'-cyclic AMP synthetase; ATP diphosphate-lyase (cyclizing). Enzyme Commission Number: EC 4.6.1.1. CAS No. 9012-42-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5348; adenylate cyclase; EC 4.6.1.1; 9012-42-4; adenylylcyclase; adenyl cyclase; 3',5'-cyclic AMP synthetase; ATP diphosphate-lyase (cyclizing). Cat No: EXWM-5348.
adenylate dimethylallyltransferase
Involved in the biosynthesis of cytokinins in plants. Some isoforms from the plant Arabidopsis thaliana are specific for AMP while others also have the activity of EC 2.5.1.112, adenylate dimethylallyltransferase (ADP/ATP-dependent). Group: Enzymes. Synonyms: cytokinin synthase (ambiguous); isopentenyltransferase (ambiguous); 2-isopentenyl-diphosphate:AMP Δ2-isopentenyltransferase; adenylate isopentenyltransferase (ambiguous); IPT. Enzyme Commission Number: EC 2.5.1.27. CAS No. 72840-95-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2764; adenylate dimethylallyltransferase; EC 2.5.1.27; 72840-95-0; cytokinin synthase (ambiguous); isopentenyltransferase (ambiguous); 2-isopentenyl-diphosphate:AMP Δ2-isopentenyltransferase; adenylate isopentenyltransferase (ambiguous); IPT. Cat No: EXWM-2764.
Involved in the biosynthesis of cytokinins in plants. The IPT4 isoform from the plant Arabidopsis thaliana is specific for ADP and ATP. Other isoforms, such as IPT1 from Arabidopsis thaliana and the enzyme from the common hop, Humulus lupulus, also have a lower activity with AMP (cf. EC 2.5.1.27, adenylate dimethylallyltransferase). Group: Enzymes. Synonyms: cytokinin synthase (ambiguous); isopentenyltransferase (ambiguous); 2-isopentenyl-diphosphate:ADP/ATP Δ2-isopentenyltransferase; adenylate isopentenyltransferase (ambiguous); dimethylallyl diphosphate:ATP/ADP isopentenyltransferase: IPT. Enzyme Commission Number: EC 2.5.1.112. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2728; adenylate dimethylallyltransferase (ADP/ATP-dependent); EC 2.5.1.112; cytokinin synthase (ambiguous); isopentenyltransferase (ambiguous); 2-isopentenyl-diphosphate:ADP/ATP Δ2-isopentenyltransferase; adenylate isopentenyltransferase (ambiguous); dimethylallyl diphosphate:ATP/ADP isopentenyltransferase: IPT. Cat No: EXWM-2728.
adenylate kinase
Inorganic triphosphate can also act as donor. Group: Enzymes. Synonyms: myokinase; 5'-AMP-kinase; adenylic kinase; adenylokinase. Enzyme Commission Number: EC 2.7.4.3. CAS No. 9013-2-9. Myokinase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3212; adenylate kinase; EC 2.7.4.3; 9013-02-9; myokinase; 5'-AMP-kinase; adenylic kinase; adenylokinase. Cat No: EXWM-3212.
adenylosuccinate lyase
Also acts on 1-(5-phosphoribosyl)-4-(N-succinocarboxamide)-5-aminoimidazole. Group: Enzymes. Synonyms: adenylosuccinase; succino AMP-lyase; 6-N-(1,2-dicarboxyethyl)AMP AMP-lyase; 6-N-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming). Enzyme Commission Number: EC 4.3.2.2. CAS No. 9027-81-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5297; adenylosuccinate lyase; EC 4.3.2.2; 9027-81-0; adenylosuccinase; succino AMP-lyase; 6-N-(1,2-dicarboxyethyl)AMP AMP-lyase; 6-N-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming). Cat No: EXWM-5297.
adenylosuccinate synthase
In molecular biology, Adenylosuccinate synthase (EC 6.3.4.4.) is an enzyme that plays an important role in purine biosynthesis, by catalysing the guanosine triphosphate (GTP)-dependent conversion of inosine monophosphate (IMP) and aspartic acid to guanosine diphosphate (GDP), phosphate and N(6)-(1,2-dicarboxyethyl)-AMP. Group: Enzymes. Synonyms: IMP-aspartate ligase; adenylosuccinate synthetase; succinoadenylic kinosynthetase; succino-AMP synthetase. Enzyme Commission Number: EC 6.3.4.4. CAS No. 9023-57-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5796; adenylosuccinate synthase; EC 6.3.4.4; 9023-57-8; IMP-aspartate ligase; adenylosuccinate synthetase; succinoadenylic kinosynthetase; succino-AMP synthetase. Cat No: EXWM-5796.
Adenylosuccinic acid
Adenylosuccinic acid (Adenylosuccinate; Aspartyl adenylate) is a purine ribonucleoside monophosphate and plays a role in nucleotide cycle metabolite. Adenylosuccinic acid can be converted into fumaric acid through adenylosuccinate lyase. Adenylosuccinic acid has the potential for the study of duchenne muscular dystrophy(DMD) [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Adenylosuccinate; Aspartyl adenylate. CAS No. 19046-78-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-127137.
Adenylosuccinic acid
Adenylosuccinic acid is a vital compound in the biomedical industry used primarily in the research of inherited metabolic disorders, such as adenylosuccinate lyase deficiency. Synonyms: Adenylosuccinic acid; 19046-78-7; Aspartyl adenylate; adenylosuccinate; Succinyl AMP; X1B4ZJ0IIV; Succinyladenosine 5'-monophosphate; N6-(1,2-dicarboxyethyl)-AMP; L-Aspartic acid, N-[9-(5-O-phosphono-beta-D-ribofuranosyl)-9H-purin-6-yl]-; 2-[9-(3,4-DIHYDROXY-5-PHOSPHONOOXYMETHYL-TETRAHYDRO-FURAN-2-YL)-9H-PURIN-6-YLAMINO]-SUCCINIC ACID; Succinyladenosine monophosphoric acid; L-Aspartic acid, N-(9-(5-O-phosphono-beta-D-ribofuranosyl)-9H-purin-6-yl)-; N (6)- (1, 2-dicarboxyethyl)AMP; (2S)-2-[ (9-{ (2R, 3R, 4S, 5R)-3, 4-dihydroxy-5-[ (phosphonooxy)methyl]tetrahydrofuran-2-yl}-9H-purin-6-yl)amino]butanedioic acid (non-preferred name). Grades: 95%. CAS No. 19046-78-7. Molecular formula: C14H18N5O11P. Mole weight: 463.29.
Adenylyl-(3'-5')-adenosine
Adenylyl-(3'-5')-adenosine is a pivotal biomolecule with extensive applications in studying signaling pathways, particularly cAMP-dependent processes. It aids in understanding cyclic nucleotide metabolism and exploring associated afflictions encompassing cancer, diabetes and cardiovascular disorders. Synonyms: ApA RNA Dinucleotide (5'-3'). CAS No. 2391-46-0. Molecular formula: C20H25N10O10P. Mole weight: 596.40.
Adenylyl-3'-5'-adenosine ammonium salt
Adenylyl-3'-5'-adenosine ammonium salt, a paramount substance utilized in the realm of biomedicine, assumes a pivotal function in the amelioration of diverse maladies encompassing cancer, cardiovascular afflictions, and metabolic irregularities. By adeptly modulating intracellular signaling cascades, this groundbreaking agent efficaciously facilitates the inception of precisely tailored remedies targeted at combating these ailments. Synonyms: Adenosine, adenylyl-(3'.5')-, ammonium salt; 21027-46-3; EINECS 244-153-3; azanium; [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] phosphate. CAS No. 21027-46-3. Molecular formula: C20H25N10O10P. Mole weight: 596.45.
Adenylyl-(3'-5')-adenosine monoammonia salt
Adenylyl-(3'-5')-adenosine monoammonia salt is a vital compound utilized in biomedical research. It is commonly employed for studying intracellular signaling pathways and second messengers, including cAMP (cyclic adenosine monophosphate). This product plays a crucial role in investigating the activation and regulation of various enzymes, receptors, and ion channels involved in multiple diseases, such as cancer, cardiovascular disorders, and neurological conditions. Its high purity and quality ensure accurate and reliable experimental results. Synonyms: ADENYLYL(3'-5')ADENOSINE; APA. Grades: 95%. CAS No. 102029-96-9. Molecular formula: C20H25N10O10P.NH3. Mole weight: 613.48.
Adenylyl-3'-5'-cytidine
Adenylyl-3'-5'-cytidine is a highly effective and specialized adenylyl cyclase activator, holding applications in biomedical research for investigating the cyclic adenosine monophosphate (cAMP) signaling pathways. Uses: Enzyme inhibitors. Synonyms: Adenylyl-3'-5'-D-cytidine. Grades: 98%. CAS No. 2382-66-3. Molecular formula: C19H25N8O11P. Mole weight: 572.42.
Adenylyl-3'-5'-cytidine
Adenylyl-3'-5'-cytidine. Group: Biochemicals. Grades: Highly Purified. CAS No. 2382-66-3. Pack Sizes: 500ug, 1mg, 2mg, 5mg. Molecular Formula: C19H25N8O11P. US Biological Life Sciences.
Worldwide
ADENYLYL-(3'-5')-GUANOSINE
ADENYLYL-(3'-5')-GUANOSINE, a fundamental molecule in cellular signaling pathways, is an indispensable regulator of intracellular communication. It assumes a pivotal position in the control of diverse biological phenomena encompassing DNA synthesis and repair, cell growth, as well as immune responses. In the realm of biomedicine, ADENYLYL-(3'-5')-GUANOSINE finds utility in the investigation of second messenger signaling, cyclic nucleotide regulation, and the therapeutic management of afflictions including cancer, cardiovascular disorders, and neurodegenerative conditions. Synonyms: Guanosine, adenylyl-(3'?5')-; 3'-Adenylic acid, 5'-ester with guanosine; Adenylyl-(3'?5')-guanosine; A-G; Adenosine, guanylyl-(5'?3')-; NSC 91554; ((2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl ((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl) hydrogen phosphate; 3'-O-(5'-Guanylyl)adenosine. Grades: ≥95%. CAS No. 3352-23-6. Molecular formula: C20H25N10O11P. Mole weight: 612.45.
Adenylyl-(3'-5')-uridine
Adenylyl-(3'-5')-uridine, a vital nucleotide and second messenger molecule, plays a crucial role in various physiological processes like regulating insulin secretion, platelet aggregation, smooth muscle relaxation, and memory consolidation. Synonyms: ApU RNA Dinucleotide (5'-3'). Molecular formula: C19H24N7O12P. Mole weight: 573.40.
Adenylyl-(3'->5')uridine 3'-Monophosphate
Adenylyl(3'->5')uridine 3'-Monophosphate is a nucleic acid sequence which may be used in the development of pharmaceuticals. Synonyms: (2R, 3S, 4R, 5R)-2- ( ( ( ( ( (2R, 3S, 4R, 5R)-5- (6-Amino-9H-purin-9-yl)-4-hydroxy-2- (hydroxymethyl)tetrahydrofuran-3-yl)oxy) (hydroxy)phosphoryl)oxy)methyl)-5- (2, 4-dioxo-3, 4-dihydropyrimidin-1 (2H)-yl)-4-hydroxytetrahydrofuran-3-yl Dihydrogen Phosphate. Molecular formula: C19H25N7O15P2. Mole weight: 653.39.
Adenylyl-3'-5'-uridine ammonium salt
Adenylyl-3'-5'-uridine ammonium salt is a versatile biochemical reagent utilized in several applications, including substrates for adenylyl cyclase, and researching cyclic nucleotide signaling. Its potential as a therapeutic agent is apparent in its integral role within the development of antiviral drugs against Hepatitis C Virus (HCV) infection. Molecular formula: C19H24N7O12P. Mole weight: 573.41.
Adenylyl-3'-5'-uridine ammonium salt
Adenylyl-3'-5'-uridine ammonium salt. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences.
Worldwide
Adenylyl-imidodiphosphate,tetralithium salt
Adenylyl-imidodiphosphate,tetralithium salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AMP-PNP, Adenylyl imidodiphosphate tetralithium salt, AGN-PC-015JO6, 5-ADENYLYL-beta,gamma-IMIDODIPHOSPHATE, beta,beta-Imidoadenosine 5-triphosphate tetralithium salt, 72957-42-7, tetralithium;[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-(phosphonatoamino)phosphinate, tetraLithoTab ({[5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonato}oxyphosphinato)aminophosphonate. Product Category: Heterocyclic Organic Compound. CAS No. 72957-42-7. Molecular formula: C10H13Li4N6O12P3. Mole weight: 529.93. Purity: 0.96. IUPACName: tetralithium;[[5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-(phosphonatoamino)phosphinate. Canonical SMILES: [Li+].[Li+].[Li+].[Li+].C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)([O-])OP(=O)(NP(=O)([O-])[O-])[O-])O)O. ECNumber: 277-127-5. Product ID: ACM72957427. Alfa Chemistry ISO 9001:2015 Certified.
adenylylsulfatase
This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in sulfonyl-containing anhydrides. The systematic name of this enzyme class is adenylyl-sulfate sulfohydrolase. Other names in common use include adenosine 5-phosphosulfate sulfohydrolase, and adenylylsulfate sulfohydrolase. This enzyme participates in sulfur metabolism. Group: Enzymes. Synonyms: adenosine 5-phosphosulfate sulfohydrolase; adenylylsulfate sulfohydrolase. Enzyme Commission Number: EC 3.6.2.1. CAS No. 37289-36-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4644; adenylylsulfatase; EC 3.6.2.1; 37289-36-4; adenosine 5-phosphosulfate sulfohydrolase; adenylylsulfate sulfohydrolase. Cat No: EXWM-4644.
adenylylsulfate-ammonia adenylyltransferase
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). Group: Enzymes. Synonyms: APSAT; adenylylsulfate:ammonia adenylyltransferase. Enzyme Commission Number: EC 2.7.7.51. CAS No. 79121-94-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3264; adenylylsulfate-ammonia adenylyltransferase; EC 2.7.7.51; 79121-94-1; APSAT; adenylylsulfate:ammonia adenylyltransferase. Cat No: EXWM-3264.
adenylyl-sulfate kinase
The human phosphoadenosine-phosphosulfate synthase (PAPSS) system is a bifunctional enzyme (fusion product of two catalytic activities). In a first step, sulfate adenylyltransferase catalyses the formation of adenosine 5'-phosphosulfate (APS) from ATP and inorganic sulfate. The second step is catalysed by the adenylylsulfate kinase portion of 3'-phosphoadenosine 5'-phosphosulfate (PAPS) synthase, which involves the formation of PAPS from enzyme-bound APS and ATP. In contrast, in bacteria, yeast, fungi and plants, the formation of PAPS is carried out by two individual polypeptides, sulfate adenylyltransferase (EC 2.7.7.4) and adenylyl-sulfate kinase (EC 2.7.1.25). Group: Enzymes. Synonyms: adenylylsulfate kinase (phosphorylating); 5'-phosphoadenosine sulfate kinase; adenosine 5'-phosphosulfate kinase; adenosine phosphosulfate kinase; adenosine phosphosulfokinase; . Enzyme Commission Number: EC 2.7.1.25. CAS No. 9012-38-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3055; adenylyl-sulfate kinase; EC 2.7.1.25; 9012-38-8; adenylylsulfate kinase (phosphorylating); 5'-phosphoadenosine sulfate kinase; adenosine 5'-phosphosulfate kinase; adenosine phosphosulfate kinase; adenosine phosphosulfokinase; adenosine-5'-phosphosulfate-3'-phosphokinase; APS kinase. Cat No: EXWM-3055.
adenylyl-sulfate reductase
An iron flavoprotein (FAD). Methyl viologen can act as acceptor. Group: Enzymes. Synonyms: adenosine phosphosulfate reductase; adenosine 5'-phosphosulfate reductase; APS-reductase; APS reductase; AMP, sulfite:(acceptor) oxidoreductase (adenosine-5'-phosphosulfate-forming). Enzyme Commission Number: EC 1.8.99.2. CAS No. 9027-75-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1685; adenylyl-sulfate reductase; EC 1.8.99.2; 9027-75-2; adenosine phosphosulfate reductase; adenosine 5'-phosphosulfate reductase; APS-reductase; APS reductase; AMP, sulfite:(acceptor) oxidoreductase (adenosine-5'-phosphosulfate-forming). Cat No: EXWM-1685.
adenylyl-sulfate reductase (glutathione)
This enzyme differs from EC 1.8.99.2, adenylyl-sulfate reductase, in using glutathione as the reductant. Glutathione can be replaced by γ-glutamylcysteine or dithiothreitol, but not by thioredoxin, glutaredoxin or mercaptoethanol. The enzyme from the mouseear cress, Arabidopsis thaliana, contains a glutaredoxin-like domain. The enzyme is also found in other photosynthetic eukaryotes, e.g., the Madagascar periwinkle, Catharanthus roseus and the hollow green seaweed, Enteromorpha intestinalis. Group: Enzymes. Synonyms: 5'-adenylylsulfate reductase (also used for EC 1.8.99.2); AMP,sulfite:oxidized-glutathione oxidoreductase (adenosine-5'-phosphosulfate-forming); plant-type 5'-adenylylsulfate reductase. Enzyme Commission Number: EC 1.8.4.9. CAS No. 355840-27-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1675; adenylyl-sulfate reductase (glutathione); EC 1.8.4.9; 355840-27-6; 5'-adenylylsulfate reductase (also used for EC 1.8.99.2); AMP,sulfite:oxidized-glutathione oxidoreductase (adenosine-5'-phosphosulfate-forming); plant-type 5'-adenylylsulfate reductase. Cat No: EXWM-1675.
adenylyl-sulfate reductase (thioredoxin)
Uses adenylyl sulfate, not phosphoadenylyl sulfate, distinguishing this enzyme from EC 1.8.4.8, phosphoadenylyl-sulfate reductase (thioredoxin). Uses thioredoxin as electron donor, not glutathione or other donors, distinguishing it from EC 1.8.4.9 [adenylyl-sulfate reductase (glutathione)] and EC 1.8.99.2 (adenylyl-sulfate reductase). Group: Enzymes. Synonyms: thioredoxin-dependent 5'-adenylylsulfate reductase. Enzyme Commission Number: EC 1.8.4.10. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1665; adenylyl-sulfate reductase (thioredoxin); EC 1.8.4.10; thioredoxin-dependent 5'-adenylylsulfate reductase. Cat No: EXWM-1665.
Adepantin-1
Adepantin-1 is an antimicrobial peptide produced by Synthetic construct. It has antibacterial activity against Gram-negative bacteria. It has hemolytic activity. Synonyms: Automatically Designed Peptide antibacterial 1; Gly-Ile-Gly-Lys-His-Val-Gly-Lys-Ala-Leu-Lys-Gly-Leu-Lys-Gly-Leu-Leu-Lys-Gly-Leu-Gly-Glu-Ser-NH2. Grades: 97%. Molecular formula: C102H183N31O26. Mole weight: 2259.78.
Aderbasib
Aderbasib is a azaspiro[2. 5]octanehydroxamide derivative as inhibitor of metalloproteases for the treatment of disorders such as cancer, arthritis, cardiovascular or skin disorders. Aderbasib, also known as INCB007839, is a sheddase inhibitor, is also an orally bioavailable inhibitor of the ADAM (A Disintegrin And Metalloprotease) family of multifunctional membrane-bound proteins with potential antineoplastic activity. Aderbasib represses the metalloproteinase "sheddase" activities of ADAM10 and ADAM17, which may result in the inhibition of tumor cell proliferation. The metalloproteinase domains of ADAMs cleave cell surface proteins at extracellular sites proximal to the cell membrane, releasing or "shedding" soluble protein etcodomains from the cell surface; the disintegrin domains of these multifunctional proteins interact with various components of the extracellular matrix (ECM). Group: Biochemicals. Alternative Names: (6S, 7S) -7-[ (Hydroxyamino) carbonyl]-6-[ (4-phenyl-1-piperazinyl) carbonyl]-5-azaspiro[2. 5]octane-5-carboxylic Acid Methyl Ester; INCB 007839. Grades: Highly Purified. CAS No. 791828-58-5. Pack Sizes: 1mg, 5mg. Molecular Formula: C??H??N?O?, Molecular Weight: 416.47. US Biological Life Sciences.
Worldwide
Aderbasib
Aderbasib is a sheddase inhibitor, is also an orally bioavailable inhibitor of the ADAM (A Disintegrin And Metalloprotease) family of multifunctional membrane-bound proteins with potential antineoplastic activity. Aderbasib represses the metalloproteinase "sheddase" activities of ADAM10 and ADAM17, which may result in the inhibition of tumor cell proliferation. Synonyms: INCB7839; INCB 7839; INCB-7839; INCB007839; INCB 007839; INCB-007839. CAS No. 791828-58-5. Molecular formula: C21H28N4O5. Mole weight: 416.48.