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| Product | Description | |
|---|---|---|
| AF430 NHS ester | AF430 is a dye. The fluorophore is hydrophilic. It is used in flow cytometry and other applications.,The NHS ester functional group allows to conjugate the fluorophore efficiently with primary and secondary amine groups in both aqueous buffers and anhydrous conditions. Grades: NMR 1H, HPLC-MS (95%). CAS No. 467233-94-9. Molecular formula: C32H42N3F3O9S. Mole weight: 701.75. |  |
| AF488 azide | AF488 is a fluorescent dye. AF488 is a fluorophore pH-insensitive over a broad pH range (from 4 to 10). It has an absorption maximum at 495 nm and an emission maximum at 519 nm in the green spectrum region. The dye is hydrophilic and can be used to introduce the fluorescent label into various molecules, including proteins and antibodies. Conjugates of molecules with AF488 have high brightness and photostability and are commonly used in flow cytometry and microscopy. This allows the detection of biological objects with high sensitivity at a longer imaging time.,AF488 azide interacts with alkynyl derivatives of biomolecules in Click Chemistry reactions either in the presence of copper (I) catalyst (with terminal alkynes) or without catalyst (with cyclooctynes), leading to the formation of stable adducts. Grades: NMR 1H, HPLC-MS (95%). CAS No. 1679326-36-3 (with azidohexyl group). Molecular formula: C36H56N8O10S2. Mole weight: 825.01. | |
| AF594 activated ester, 5-isomer | AF594 is a bright water-soluble dye that is not sensitive to pH changes within the range from 4 to 10. This red-fluorescent dye is the best alternative to Texas Red, so it is commonly used for flow cytometry and fluorescent microscopy.,AF594 activated ester is used for labeling proteins, peptides, antibodies, and any molecules containing an -NH2 group (such as amino-modified oligonucleotides); it results in the formation of stable amide bonds between the dye and the target molecule. The best result in conjugation reaction achieved at pH from 7 to 9.,AF594 can be used for protein labeling with a high molar dye-to-protein ratio. The resulting conjugates with a high degree of labeling (DOL) do not exhibit significant fluorescence quenching. In contrast, the conjugates have brighter fluorescence, which allows increasing the lowest limit of detection of the labeled product. Grades: NMR 1H, HPLC-MS (95%). CAS No. 1638544-48-5. Molecular formula: C51H67N5O13S2. Mole weight: 1022.23. | |
| Afabicin | Afabicin (formerly Debio 1450, AFN-1720) is a prodrug of afabicin desphosphono, an enoyl-acyl carrier protein reductase (FabI) inhibitor, and is a first-in-class antibiotic with a novel mode of action to specifically target fatty acid synthesis in Staphylococcus spp. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Afabicin; Debio 1450; Debio-1450; Debio1450; AFN-1720; AFN 1720; AFN1720. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1518800-35-5. Molecular formula: C23H24N3O7P. Mole weight: 485.43. Purity: >98%. IUPACName: (E)-(6-(3-(methyl((3-methylbenzofuran-2-yl)methyl)amino)-3-oxoprop-1-en-1-yl)-2-oxo-3,4-dihydro-1,8-naphthyridin-1(2H)-yl)methyl dihydrogen phosphate. Canonical SMILES: O=P(O)(OCN1C(CCC2=CC(/C=C/C(N(C)CC(O3)=C(C)C4=C3C=CC=C4)=O)=CN=C12)=O)O. Product ID: ACM1518800355. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Afabicin | Afabicin (Debio 1450) is the proagent of Debio1452, specifically targeting staphylococci without significant activity against other Gram-positive or Gram-negative species. Debio1452 is an inhibitor FabI , an enzyme critical to fatty acid biosynthesis in staphylococci. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Debio 1450; AFN-1720. CAS No. 1518800-35-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-109000. |  |
| Afacifenacin | Afacifenacin acts as a sodium/calcium exchanger inhibitor used in the prevention of reperfusion injury associated with restoration of coronary blood flow via surgery. Synonyms: (S)-(+)-3-[1-[3-(Trifluoromethoxy)benzyl]piperidin-4-yl]-4-phenyl-3,4-dihydro-1H-quinazolin-2-one. Grades: > 95%. CAS No. 877606-63-8. Molecular formula: C27H26F3N3O2. Mole weight: 481.52. | |
| A-factor | It is produced by the strain of streptomyces griseus. It can not only promote the formation of spores and air hyphae by streptomycin, but also restore the ability of non-production mutants to produce streptomycin, which is the so-called Autoregulator. Synonyms: 2-Isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone; Q27144309; SCHEMBL6026457; DTXSID00965600; 4-(HYDROXYMETHYL)-3-(6-METHYLHEPTANOYL)OXOLAN-2-ONE; 2(3H)-Furanone, dihydro-4-(hydroxymethyl)-3-(6-methyl-1-oxoheptyl)-, (4R)-; (-)-A factor; (R)-4-Hydroxymethyl-3-(6-methyl-heptanoyl)-dihydro-furan-2-one. CAS No. 51311-41-2. Molecular formula: C13H22O4. Mole weight: 242.31. | |
| Afatinib | Afatinib irreversibly inhibits EGFR/HER2 including EGFR, EGFR(L858R), EGFR(L858R/T790M) and HER2. It is 100-fold more active against Gefitinib-resistant L858R-T790M EGFR mutant. Uses: Antineoplastic agents. Synonyms: 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-, (2E)-; (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide; BIBW 2992; Gilotrif; Giotrif; Tovok; (S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide. Grades: >98%. CAS No. 850140-72-6. Molecular formula: C24H25ClFN5O3. Mole weight: 485.94. | |
| Afatinib | Afatinib (BIBW 2992) is an orally active, potent and irreversible dual specificity inhibitor of ErbB family ( EGFR and HER2 ), with IC 50 values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFR wt , EGFR L858R , EGFR L858R/T790M and HER2, respectively. Afatinib can be used for the research of esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC) and gastric cancer [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BIBW 2992. CAS No. 850140-72-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10261. | |
| Afatinib-[d6] | Afatinib-[d6] is the labelled analogue of Afatinib. Afatinib is a medication approved for the treatment of metastatic non-small cell lung cancer (NSCLC) that has certain EGFR mutations. It acts via inhibiting EGFR and HER2. Synonyms: Afatinib-d6; (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide-d6; BIBW 2992-d6; Tovok-d6; Tomtovok-d6. Grades: 97%; ≥99% atom D. CAS No. 1313874-96-2. Molecular formula: C24H19D6ClFN5O3. Mole weight: 491.98. | |
| Afatinib-des(4-dimethylamino-2-en-1-oxo)butyl (Contained ~8.5% Ethanol) | Afatinib-des(4-dimethylamino-2-en-1-oxo)butyl is a reactant in the synthesis of Afatinib (A355300), an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder. Group: Biochemicals. Grades: Highly Purified. CAS No. 314771-76-1. Pack Sizes: 100mg, 1g. Molecular Formula: C18H16ClFN4O2. US Biological Life Sciences. |  Worldwide |
| Afatinib dimaleate | Afatinib (BIBW 2992) dimaleate is an orally active, potent and irreversible dual specificity inhibitor of ErbB family ( EGFR and HER2 ), with IC 50 values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFR wt , EGFR L858R , EGFR L858R/T790M and HER2, respectively. Afatinib dimaleate can be used for the research of esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC) and gastric cancer [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BIBW 2992MA2. CAS No. 850140-73-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10261A. | |
| Afatinib Impurity 2 | An analogue of Afatinib. Synonyms: 7-Quinazolinol, 4-[(3-chloro-4-fluorophenyl)?amino]?-6-nitro-. Grades: > 95%. CAS No. 1449430-45-8. Molecular formula: C14H8ClFN4O3. Mole weight: 334.7. | |
| Afatinib impurity 20 | Afatinib impurity 20. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1027929-81-2. Molecular formula: C8H4FN3O3. Mole weight: 209.14. Catalog: APB1027929812. |  |
| Afatinib Impurity 2F3Cl-1 | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: 4-Quinazolinamine, N-(3-chloro-2-fluorophenyl)-7-fluoro-6-nitro-. Grades: ≥95%. CAS No. 936558-43-9. Molecular formula: C14H7ClF2N4O2. Mole weight: 336.68. | |
| Afatinib Impurity 5 | An analogue of Afatinib. Synonyms: 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)?-7-methoxy-6-nitro-. Grades: > 95%. CAS No. 179552-74-0. Molecular formula: C15H10ClFN4O3. Mole weight: 348.72. | |
| Afatinib Impurity 52 | Afatinib Impurity 52 is an impurity of Afatinib, a drug used to treat non-small cell lung cancer (NSCLC). Synonyms: (S)-diethyl 2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamino)-2-oxoethylphosphonate; Diethyl {[4-(3-Chloro-4-Fluoro-Phenylamino)-7-((S)-Tetrahydrofuran-3-Yloxy)-Quinazolin-6-Ylcarbamoyl]-Methyl}-Phosphonate. Grades: 95%. CAS No. 618061-76-0. Molecular formula: C24H27ClFN4O6P. Mole weight: 552.92. | |
| Afatinib impurity 69 | Afatinib impurity 69. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-4-chloro-3-hydroxybutanoic acid. CAS No. 106941-19-9. Molecular formula: C4H7ClO3. Mole weight: 138.55. Catalog: APB106941199. | |
| Afatinib Impurity A | An analogue of Afatinib. Synonyms: 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)?-6-nitro-7-[[(3R)?-tetrahydro-3-furanyl]?oxy]?-. Grades: > 95%. CAS No. 402855-07-6. Molecular formula: C18H14ClFN4O4. Mole weight: 404.79. | |
| Afatinib Impurity AFT-8 | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: Afatinib Impurity QJJ; N-[4-((3-Chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)-3-hydroxybutenamide; Butanamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-3-hydroxy-. Grades: ≥95%. CAS No. 2323570-72-3. Molecular formula: C24H27ClFN5O4. Mole weight: 503.95. | |
| Afatinib Impurity B | An analogue of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: Afatinib-des(4-dimethylamino-2-en-1-oxo)butyl; N4-(3-Chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]-4,6-quinazolinediamine; (S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine. Grades: > 95%. CAS No. 314771-76-1. Molecular formula: C18H16ClFN4O2. Mole weight: 374.81. | |
| Afatinib Impurity C | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)?amino]?-7-[[(3R)?-tetrahydro-3-furanyl]?oxy]?-6-quinazolinyl]?-4-(dimethylamino)?-, (2E)?-. Grades: > 95%. CAS No. 945553-91-3. Molecular formula: C24H25ClFN5O3. Mole weight: 485.95. | |
| Afatinib Impurity CSEJXA | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: (S)-N1-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-N2,N2-dimethyloxalamide (Afatinib Impurity; (S)-N1-(4-((3-CHLORO-4-FLUOROPHENYL)AMINO)-7-((TETRAHYDROFURAN-3-YL)OXY)QUINAZOLIN-6-YL)-N2,N2-DIMETHYLOXALAMIDE; Afatinib Impurity CSEJXA; CS-0164258; E82032; (S)-N1-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-N2,N2-dimethyloxalamide (Afatinib Impurity pound(c). Grades: ≥95%. CAS No. 2223677-66-3. Molecular formula: C22H21ClFN5O4. Mole weight: 473.88. | |
| Afatinib Impurity CSZ | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Grades: ≥95%. Molecular formula: C22H20ClFN4O5. Mole weight: 474.87. | |
| Afatinib impurity D | Afatinib impurity D. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S,Z)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide; Z-Afatinib. CAS No. 1680184-59-1. Molecular formula: C24H25ClFN5O3. Mole weight: 485.94. Catalog: APB1680184591. | |
| Afatinib Impurity D | An analogue of Afatinib, a medication indicated for the treatment of non-small cell lung carcinoma (NSCLC). Synonyms: (2Z)-Afatinib; Z-Afatinib; (S,Z)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide. Grades: > 95%. CAS No. 1680184-59-1. Molecular formula: C24H25ClFN5O3. Mole weight: 485.95. | |
| Afatinib Impurity ESS | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Grades: ≥95%. Molecular formula: C30H34ClFN6O4. Mole weight: 597.09. | |
| Afatinib Impurity I | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: Bromo-Afatinib; (S,E)-4-bromo-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide. Grades: ≥95%. CAS No. 1637254-93-3. Molecular formula: C22H19BrClFN4O3. Mole weight: 521.78. | |
| Afatinib Impurity J | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: (2E)-N-[3,4-Dihydro-4-oxo-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide; (S,E)-4-(DIMETHYLAMINO)-N-(4-HYDROXY-7-((TETRAHYDROFURAN-3-YL)OXY)QUINAZOLIN-6-YL)BUT-2-ENAMIDE; (S,e)-4-(dimethylamino)-N-(4-oxo-7-((tetrahydrofuran-3-yl)oxy)-3,4-dihydroquinazolin-6-yl)but-2-enamide; Afatinib Impurity J; SCHEMBL17352060; SCHEMBL17352063; GSUSIQVMAQBROU-PCAWENJQSA-N; CS-0164268; E82037; (S,E)-4-(Dimethylamino)-N-(4-hydroxy-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide (Afatinib Impurity). Grades: > 95%. CAS No. 1456696-14-2. Molecular formula: C18H22N4O4. Mole weight: 358.4. | |
| Afatinib Impurity JXH | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]formamide; Des(N,N-Dimethylprop-2-enyl-1-Amine) Afatinib. Grades: ≥95%. CAS No. 2223677-60-7. Molecular formula: C19H16ClFN4O3. Mole weight: 402.81. | |
| Afatinib Impurity N-Oxide | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: (S,E)-4-((4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)amino)-N,N-dimethyl-4-oxobut-2-en-1-amine oxide. Grades: ≥95%. CAS No. 2413212-11-8. Molecular formula: C24H25ClFN5O4. Mole weight: 501.94. | |
| Afatinib Impurity O | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: (S,E)-4-broMo-N-(4-((3-chloro-4-fluorophenyl)aMino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enaMide; (E)-4-bromo-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]but-2-enamide; Bromo-Afatinib; C22H19BrClFN4O3; AFATINIB IMPURITY O; SCHEMBL16398947; SCHEMBL16398952; IQJWAIKYBNTYPG-YUKKFKLSSA-N; CS-0164267; (2E)-4-Bromo-N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-2-butenamide; (S,E)-4-Bromo-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide (Afatinib Impurity). Grades: ≥95%. Molecular formula: C18H15FN4O4. Mole weight: 370.34. | |
| Afatinib Impurity Q | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Grades: ≥95%. Molecular formula: C14H7ClF2N4O2. Mole weight: 336.68. | |
| Afatinib Impurity QA | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Grades: ≥95%. Molecular formula: C18H16ClFN4O3. Mole weight: 390.80. | |
| Afatinib Impurity SCl | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: (S,E)-N-(4-((3,4-Dichlorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide. Grades: ≥95%. CAS No. 2223677-63-0. Molecular formula: C24H25Cl2N5O3. Mole weight: 502.39. | |
| Afatinib Impurity SM2A | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: 2-Butenamide, 4-(dimethylamino)-N,N-dimethyl-. Grades: ≥95%. CAS No. 1862246-17-0. Molecular formula: C8H16N2O. Mole weight: 156.23. | |
| Afatinib Impurity WZYGNH2 | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Grades: ≥95%. Molecular formula: C18H16ClFN4O2. Mole weight: 370.80. | |
| Afatinib Impurity WZYGNO2 | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Grades: ≥95%. Molecular formula: C18H14ClFN4O4. Mole weight: 404.78. | |
| AFB-guanine | AFB-guanine. Group: Biochemicals. Alternative Names: (6aS, 8R, 9R, 9aR)-8-(2-Amino-1, 6-dihydro-6-oxo-7H-purin-7-yl)-2, 3, 6a, 8, 9, 9a-hexahydro-9-hydroxy-4-methoxy-cyclopenta[c]furo[3', 2':4, 5]furo[2, 3-h][1]benzopyran-1, 11-dione. Grades: Highly Purified. CAS No. 63425-04-7. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C22H17N5O8. US Biological Life Sciences. | Worldwide |
| AFB-Guanine Acetic Acid Salt | Acetic acid of a guanine adduct of Aflatoxin B1. Synonyms: (6aS,8R,9R,9aR)-8-(2-Amino-1,6-dihydro-6-oxo-7H-purin-7-yl)-2,3,6a,8,9,9a-hexahydro-9-hydroxy-4-methoxy-cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione Acetic Acid. Grades: 95%. Molecular formula: C24H21N5O10. Mole weight: 539.45. | |
| AFC | AFC. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7-Amino-4-trifluoromethylcoumarin. Product Category: Other Fluorophores. CAS No. 53518-15-3. Molecular formula: C10H6F3NO2. Mole weight: 229.15. Product ID: ACM53518153. Alfa Chemistry ISO 9001:2015 Certified. | |
| AF-DX 116 | AF-DX 116 has been found to be a selective mAChR M2 antagonist. Synonyms: Otenzepad; AF-DX 116; AF-DX-116; AF-DX116; 11-[[2-[(Diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one. Grades: ≥98% by HPLC. CAS No. 102394-31-0. Molecular formula: C24H31N5O2. Mole weight: 421.54. | |
| AF-DX 116 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| AF-DX 116 (Muscarinic Receptor (mAChR) M2 Antagonist, AF-DX 116, Otenzepad, AF-DX116, AF-DX-116, AFDX116) | Selective presynaptic muscarinic receptor M2 antagonist with cardioselectivity. Exhibits antiarrhythmic effects in vivo, also shown to reverse the memory impairment effect of insulin in a mouse model. Group: Biochemicals. Grades: Highly Purified. CAS No. 102394-31-0. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences. | Worldwide |
| AF-DX 384 | AF-DX 384 is a selective antagonist of M2 and M4 muscarinic acetylcholine receptors ( K i s =6.03 and 10 nM, respectively) [1]. AF-DX 384 reverses deficits in novel object recognition and passive avoidance in aged rats, as well as in young rats with impairments induced by scopolamine [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 118290-26-9. Pack Sizes: 5 mg. Product ID: HY-107652. | |
| AF-DX 384 | AF-DX 384 has been found to be a mAChR M2/M4 selective antagonist. Uses: Parasympatholytics. Synonyms: N-[2-[2-[(Dipropylamino)methyl]-1-piperidinyl]ethyl]-5,6-dihydro-6-oxo-11H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide. Grades: ≥98% by HPLC. CAS No. 118290-26-9. Molecular formula: C27H38N6O2. Mole weight: 478.64. | |
| AF-DX 384 | AF-DX 384. Group: Biochemicals. Grades: Purified. CAS No. 118290-26-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AF-DX 384 Free Base | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Afegostat | Afegostat is a pharmacological chaperone, which specifically and reversibly binds acid-β-glucosidase ( GCase ) in the endoplasmic reticulum (ER) with high affinity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: D-Isofagomine; Isofagomine. CAS No. 169105-89-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-14829. | |
| Afegostat D-Tartrate | Afegostat D-Tartrate is a pharmacological chaperone, which specifically and reversibly binds acid-β-glucosidase ( GCase ) in the endoplasmic reticulum (ER) with high affinity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: D-Isofagomine D-Tartrate; Isofagomine D-Tartrate. CAS No. 957230-65-8. Pack Sizes: 1 mg. Product ID: HY-14829E. | |
| Afe I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA (BamHI-digest) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme more than 80% of dna pbr322 fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. AGC↑GCT TCG↓CGA. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer B, BSA. Storage: -20°C. Form: Liquid. Source: An E.coli strain that carries the cloned Afe I gene from Alcaligenes faecalis T2774. Pack: 10 mM Tris-HCl (pH 7.6); 50 mM NaCl; 0.1 mM EDTA; 1 mM DTT; 200 μg/ml BSA; 50% glycerol. Cat No: RE-1014EN. |  |
| Afelimomab | Afelimomab (MAK 195F) is an anti-tumor necrosis factor F(ab')2 monoclonal antibody fragment. Afelimomab can be used for the research of sepsis [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MAK 195F. CAS No. 156227-98-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99425. | |
| AFG206 | AFG206 is the novel first-generation "type II" FLT3 inhibitor. Synonyms: AFG-206; AFG 206. Grades: >98%. CAS No. 630122-37-1. Molecular formula: C20H19N3O2. Mole weight: 333.38. | |
| AFG210 | AFG210 is a novel first-generation "type II" FLT3 inhibitor. Synonyms: AFG 210; AFG-210; 1-(3-(trifluoromethyl)phenyl)-3-(4-(pyridin-4-yloxy)phenyl)urea. Grades: >98%. CAS No. 228400-22-4. Molecular formula: C19H14F3N3O2. Mole weight: 373.33. | |
| Aficamten | Aficamten, also known as CK-3773274 and CK-274, is a Next-Generation Cardiac Myosin Inhibitor for the Treatment of Hypertrophic Cardiomyopathy. Aficamten was designed to provide a predicted human half-life (t1/2) appropriate for once a day (qd) dosing, to reach steady state within two weeks, to have no substantial cytochrome P450 induction or inhibition, and to have a wide therapeutic window in vivo with a clear pharmacokinetic/pharmacodynamic relationship. In a phase I clinical trial, aficamten demonstrated a human t1/2 similar to predictions and was able to reach steady state concentration within the desired two-week window. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CK-3773274; CK3773274; CK 3773274; CK-274; CK274; CK 274. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2364554-48-1. Molecular formula: C18H19N5O2. Mole weight: 337.38. Purity: >98%. IUPACName: N-[(1R)-5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl]-1-methyl-1H-pyrazole-4-carboxamide. Canonical SMILES: O=C(C1=CN(C)N=C1)N[C@@H]2CCC3=C2C=CC(C4=NOC(CC)=N4)=C3. Product ID: ACM2364554481. Alfa Chemistry ISO 9001:2015 Certified. | |
| Aficamten | Aficamten (CK-274) is a potent cardiac myosin inhibitor with an IC 50 of 1.4 μM. Aficamten can be used for the research of hypertrophic cardiomyopathy (HCM) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CK-274; CK-3773274. CAS No. 2364554-48-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139465. | |
| Afimetoran | Afimetoran (BMS-986256) is an orally active, selective, and highly bioavailable TLR7/8 antagonist. Afimetoran (BMS-986256) can inhibit TLR7/8 activation of the NF-κB pathway and reverse TLR7 mediated resistance to steroid induced apoptosis in plasma cell like dendritic cells (pDCs). Afimetoran (BMS-986256) can be used for research on inflammation and autoimmune diseases (systemic lupus erythematosus) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-986256. CAS No. 2171019-55-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139567. | |
| Afimoxifene | Afimoxifene (4-hydroxytamoxifen) is a selective estrogen receptor modulator which is the active metabolite of tamoxifen. Afimoxifene is a transdermal gel formulation and is being developed by Ascend Therapeutics, Inc. under the trademark TamoGel. Afimoxifene has completed a phase II clinical trial for the treatment of cyclical mastalgia. Uses: Estrogen antagonists. Synonyms: (E/Z)-4-Hydroxytamoxifen; 4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol; TamoGel; Phenol, 4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-. Grades: ≥95%. CAS No. 68392-35-8. Molecular formula: C26H29NO2. Mole weight: 387.51. | |
| Aflastatin A | It is produced by the strain of Streptomyces sp. MRI 142. Aflatoxin A has anti-Gram-positive bacteria, Pyricularia oryzae and yeast activity (MIC is 0.19-0.39 μg/mL), and inhibits the growth of adenocarcinoma 755 (1.0 mg/kg reduces tumor growth by 75% the above). Synonyms: 2,4-Pyrrolidinedione, 1, 5-dimethyl-3-(1, 8, 9, 11, 13, 15, 17, 19, 21, 23, 25, 27, 28, 29, 30, 31-hexadecahydroxy-2, 4, 6, 10, 12, 14, 18, 20-octamethyl-32-(tetrahydro-3, 4, 5, 6-tetrahydroxy-6-(2-hydroxyundecyl)-2H-pyran-2-yl)-2-dotriacontenylidene)-; LS-137668. Grades: ≥ 95%. CAS No. 179729-59-0. Molecular formula: C62H115NO24. Mole weight: 1258.56. | |
| Aflatoxicol | The 2 ppm acetonitrile solution of aflatoxicol, a metabolite of aflatoxin, could be commonly used as a standard solution. Uses: Only to be used as a reference standard in analytical laboratories. Synonyms: Aflatoxin Ro; (1S-(1alpha, 6abeta, 9abeta))-2, 3, 6a, 9a-Tetrahydro-1-hydroxy-4-methoxycyclopenta(c)furo(3', 2':4, 5)furo(2, 3-h)(1)benzopyran-11(1H)-one; Cyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-11(1H)-one, 2,3,6a,9a-tetrahydro-1-hydroxy-4-methoxy-, (1S,6aR,9aS)-; AFL. Grades: ≥98%. CAS No. 29611-03-8. Molecular formula: C17H14O6. Mole weight: 314.29. | |
| Aflatoxicol | Aflatoxin (Aflatoxin R0) is a metabolite of aflatoxin B1 produced from Rhizopus spp [1] , and is mutagenic and carcinogenic mycotoxin [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Aflatoxin R0. CAS No. 29611-03-8. Pack Sizes: 1 mg. Product ID: HY-N6695. | |
| AFLATOXICOL I NATURAL ISOMER VACUUM DRIED | AFLATOXICOL I NATURAL ISOMER VACUUM DRIED. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (1R,6aS,9aS)-1-Hydroxy-4-methoxy-2,3,6a,9a-tetrahydrocyclopenta[c]furo[3,2:4,5]furo[2,3-h]chromen-11(1H)-one. Product Category: Heterocyclic Organic Compound. CAS No. 29611-03-8. Molecular formula: C17H14O6. Mole weight: 314.289. Purity: 0.96. IUPACName: Aflatoxicol A. Density: 1.56g/cm³. Product ID: ACM29611038. Alfa Chemistry ISO 9001:2015 Certified. | |
| Aflatoxin B1-[13C17] | Aflatoxin B1-[13C17] is the labelled analogue of Aflatoxin B1, which is an aflatoxin produced by Aspergillus flavus and A. parasiticus. Synonyms: Aflatoxin B1-13C17. Grades: 95% atom 13C. CAS No. 1217449-45-0. Molecular formula: [13C]17H12O6. Mole weight: 329.15. | |
| Aflatoxin B1 aldehyde reductase member 2 from Human, Recombinant | Aflatoxin B1 aldehyde reductase member 2 catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Has NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2-nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). Can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro). Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen. Group: Enzymes. Synonyms: AFB1 aldehyde reductase 1; AFB1-AR 1; Aldoketoreductase 7; Succinic semialdehyde reductase. Enzyme Commission Number: EC 1.1.1.n11. AKR7A2. Mole weight: 39588.9 Da. Source: Human. AFB1 aldehyde reductase 1; AFB1-AR 1; Aldoketoreductase 7; Succinic semialdehyde reductase; EC 1.1.1.n11; AKR7A2; Aflatoxin B1 aldehyde reductase member 2. Cat No: NATE-1196. | |
| Aflatoxin B2 | Aflatoxins B1, B2, G1, G2 as secondary metabolites of fungal species such as Aspergillus flavus or Aspergillus parasiticus growing on a variety of foods (peanuts, nuts, spices, cereals). Aflatoxins are a group of very carcinogenic mycotoxins with hepatotoxic effects. Group: Biochemicals. Alternative Names: (6aR, 9aS) -2, 3, 6a, 8, 9, 9a-Hexahydro-4-methoxycyclopenta [c]furo [3, 2: 4, 5]furo [2, 3-h] [1]benzopyran-1, 11-dione; Dihydroaflatoxin B1; Dihydroaflatoxine B1. Grades: Highly Purified. CAS No. 7220-81-7. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences. | Worldwide |
| Aflatoxin (BSA) | Aflatoxins belong to the class of mycotoxins. Toxic fungal metabolite and carcinogen. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| aflatoxin B synthase | A heme-thiolate (P-450) enzyme. Isolated from the mold Aspergillus parasiticus. Group: Enzymes. Synonyms: ordA (gene name); 8-O-methylsterigmatocystin,NADPH:O2 oxidoreductase (aflatoxin-B forming). Enzyme Commission Number: EC 1.14.13.175. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0773; aflatoxin B synthase; EC 1.14.13.175; ordA (gene name); 8-O-methylsterigmatocystin,NADPH:O2 oxidoreductase (aflatoxin-B forming). Cat No: EXWM-0773. | |
| Aflatoxin G1 | Aflatoxin G1 is the major analogue of the green fluorescent family of bisfuranocoumarin mycotoxins produced by Aspergillus flavus and related species. Alfatoxins are one of the most potent mycotoxins known but are in fact "pre-toxins" requiring metabolic activation to the toxic principle. Aflatoxins are found widely in nature in trace amounts particularly grains and nuts. The toxicity of these metabolites was first recognised in the 1950s and their structures elucidated in 1963. Aflatoxins have been extensively reviewed. Source:Aflatoxin G1 from Aspergillus flavus. Group: Biochemicals. Alternative Names: (7aR, 10aS)-3, 4, 7a, 10a-Tetrahydro-5-methoxy-1H, 12H-furo[3, 2:4, 5]furo[2, 3-h]pyrano[3, 4-c][1]benzopyran-1, 12-dione. Grades: Highly Purified. CAS No. 1165-39-5. Pack Sizes: 1mg, 5mg. Molecular Formula: C17H12O7, Molecular Weight: ~328.3. US Biological Life Sciences. | Worldwide |
| Aflatoxin G1 | from Aspergillus flavus. Group: Fluorescence/luminescence spectroscopymycotoxinsmycotoxinschiral molecules. Alternative Names: 1H,12H-Furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c][1]benzopyran-1,12-dione, 3,4,7a,10a-tetrahydro-5-methoxy-, (7aR-cis)-, (7aR,10aS)-3,4,7a,10a-Tetrahydro-5-methoxy-1H,12H-furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c][1]benzopyran-1,12-dione, Aflatoxin G1 (7CI),1H,12H-Furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c][1]benzopyran-1,12-dione, 3,4,7a,10a-tetrahydro-5-methoxy-, (7aR,10aS)-. | |
| Aflatoxin G2 | Aflatoxins B1, B2, G1, G2 as secondary metabolites of fungal species such as Aspergillus flavus or Aspergillus parasiticus growing on a variety of foods (peanuts, nuts, spices, cereals). Aflatoxins are a group of very carcinogenic mycotoxins with hepatotoxic effects. Group: Biochemicals. Alternative Names: (7aR, 10aS)-3, 4, 7a, 9, 10, 10a-Hexahydro-5-methoxy-1H, 12H-furo[3', 2':4, 5]furo[2, 3-h]pyrano[3, 4-c][1]benzopyran-1, 12-dione. Grades: Highly Purified. CAS No. 7241-98-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
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