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| Product | Description | |
|---|---|---|
| Azapropazone dihydrate | Azapropazone dihydrate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,2-Dihydro-3-dimethylamino-7-methyl-1,2-(propylmalonyl)-1,2,4-benzotriazine dihydrate; Prolixana; Azapropazon dihydrat; Apazone dihydrate; Tolyprin; Azapropazon dihydrat [German]; Azapropazone dihydrate; 1H-Pyrazolo(1,2-a)(1,2,4)benzotriazine-1,3(2H)-dione,5-(dimethylamino)-9-methyl-2-propyl-,dihydrate; 3-Dimethylamino-7-methyl-1,2-(n-propylmalonyl)-1,2-dihydro-1,2,4-benzotriazine dihydrate. CAS No. 22304-30-9. Molecular formula: C16H24N4O4. Mole weight: 336.39. Purity: 0.96. IUPACName: 5-(dimethylamino)-9-methyl-2-propylpyrazolo[1,2-a][1,2,4]benzotriazine-1,3-dione;dihydrate. Canonical SMILES: CCCC1C(=O)N2C3=C(C=CC(=C3)C)N=C(N2C1=O)N(C)C.O.O. Density: 1.29g/cm³. Product ID: ACM22304309. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Azapropazone dihydrate | Azapropazone dihydrate is a non-steroidal anti-inflammatory agent used in the treatment of rheumatoid arthritis. It also has uricosuric properties and has been used to treat gout. Synonyms: 1H-Pyrazolo[1,2-a][1,2,4]benzotriazine-1,3(2H)-dione, 5-(dimethylamino)-9-methyl-2-propyl-, hydrate (1:2); 1H-Pyrazolo[1,2-a][1,2,4]benzotriazine-1,3(2H)-dione, 5-(dimethylamino)-9-methyl-2-propyl-, dihydrate; 1,2-Dihydro-3-dimethylamino-7-methyl-1,2-(propylmalonyl)-1,2,4-benzotriazine dihydrate; 3-Dimethylamino-7-methyl-1,2-(n-propylmalonyl)-1,2-dihydro-1,2,4-benzotriazine dihydrate; 5-(dimethylamino)-9-methyl-2-propyl-1H-pyrazolo[1,2-a][1,2,4]benzotriazine-1,3(2H)-dione dihydrate. Grade: ≥95%. CAS No. 22304-30-9. Molecular formula: C16H20N4O2.2H2O. Mole weight: 336.39. |  |
| Azarbre | Azarbre (3,4- Diethyl-2,5-Dimethyl Cyclohex-2-en-1-one). CAS No. 68845-36-3. VIGON Item # 503202. Categories: Speciality Ingredients Suppliers, Fragrances, Perfumers. |  America & Internationally |
| Azaribine | Azaribine (2',3',5'-Tri-O-acetyl-6-azauridine) is a potent orotidine monophosphate decarboxylase (OMPD) inhibitor. Azaribine is an antiviral inhibitor of several RNA viruses and inhibits viral genome replication and gene transcription. Azaribine shows broad-spectrum antiviral activity ( EC 50 =3.80?nM-1.73?μM against influenza A and B viruses; EC 50 =1.62 μM against ZIKV Paraiba). Azaribine, a triacetate salt of Azauridine, has the potential for psoriasis research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2',3',5'-Tri-O-acetyl-6-azauridine. CAS No. 2169-64-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B1537. |  |
| Azaribine | It is an antineoplastic agent. Uses: Dermatologic agents. Synonyms: AZARIBINE; Triazure; 2169-64-4; 6-Azauridine 2',3',5'-triacetate; 6-Azaribine; CB 304; Azaribinum; Azaribina; Triacetyl-6-azauridine; 6-Azauridine triacetate; CB-304; NSC-67239; Azauridine triacetate; NSC 67239; K1U80DO9EB; MLS000069488; DTXSID1022635; TA-Azur; 2-beta-D-Ribofuranosyl-as-triazine-3,5(2H,4H)-dione 2',3',5'-triacetate; 1,2,4-Triazine-3,5(2H,4H)-dione, 2-(2,3,5-tri-O-acetyl-beta-D-rib. Grade: ≥95%. CAS No. 2169-64-4. Molecular formula: C17H20O6. Mole weight: 323.35. | |
| Azaserine | Azazerine (CI-337) is a competitive inhibitor of glutamine amidotransferase. Azaserine is an antibiotic , it shows antibacterial activities. Azazerine shows anti-tumor activities and it may also act as a tumor inducer. Azazerine can be used for the research of cancer and infection [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CI-337; O-Diazoacetyl-L-serine; P-165. CAS No. 115-02-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0919. | |
| Azaserine | It is produced by the strain of Streptomyces fragilis 04926. Azaserine is a naturally occurring serine derivative diazo compound with antineoplastic properties, Azaserine functions as a purine antagonist and glutamine analogue (glutamine amidotransferase inhibitor) that competitively inhibits pathways in which glutamine is metabolized. Uses: Antibiotics, antifungal; antibiotics, antineoplastic; antimetabolites; antimetabolites, antineoplastic; carcinogens; immunosuppressive agents. Synonyms: diazoacetate (ester) L-Serine; diazoacetylserine; serine diazoacetate. Grade: 98%. CAS No. 115-02-6. Molecular formula: C5H7N3O4. Mole weight: 173.13. | |
| Azasetron-13C,D3 Hydrochloride | A 5-HT3 receptor antagonist. Used as an antiemetic. Group: Biochemicals. Alternative Names: N-1-Azabicyclo[2.2.2]-oct-3-yl-6-chloro-3,4-dihydro-4-(methyl-13C,d3)-3-oxo-2H-1,4-benzoxazine-8-carboxamide Hydrochloride. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences. |  Worldwide |
| Azasetron-[d3] Hydrochloride | Azasetron-[d3] Hydrochloride is the labelled analogue of Azasetron Hydrochloride, which is a 5-HT3 receptor antagonist and used as an antiemetic. Synonyms: Azasetron-d3 Hydrochloride; N-1-Azabicyclo[2.2.2]-oct-3-yl-6-chloro-3,4-dihydro-4-(methyl-d3)-3-oxo-2H-1,4-benzoxazine-8-carboxamide Hydrochloride; Serotone-d3; Nazasetron-d3; Y-25130-d3 hydrochloride; 6-chloro-4-methyl-3-oxo-N-(quinuclidin-3-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-8-carboxamide-d3 hydrochloride. Grade: 98%; ≥99% atom D. CAS No. 1216505-58-6. Molecular formula: C17H18D3Cl2N3O3. Mole weight: 389.29. | |
| Azasetron-d3, Hydrochloride (N-1-Azabicyclo[2.2.2]-oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-2H-1,4-benzoxazine-8-carboxamide-d3, Hydrochloride) | A 5-HT3 receptor antagonist. Used as an antiemetic. Group: Biochemicals. Alternative Names: N-1-Azabicyclo[2.2.2]-oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-2H-1,4-benzoxazine-8-carboxamide-d3, Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Azasetron hydrochloride | Azasetron (Y-25130) hydrochloride, a benzamide derivative, is a potent and selective 5-HT3 receptor antagonist. Azasetron is used in the study for Chemotherapy-induced nausea and vomiting (CINV) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Y-25130 hydrochloride. CAS No. 123040-16-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0068. | |
| Azasetron hydrochloride | Azasetron hydrochloride. Group: Biochemicals. Alternative Names: N-1-Azabicyclo[2.2.2]-oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-2H-1,4-benzoxazine-8-carboxamide hydrochloride. Grades: Highly Purified. CAS No. 123040-69-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C17H21Cl2N3O3. US Biological Life Sciences. | Worldwide |
| Azasetron hydrochloride | Azasetron HCl is a selective 5-HT3 receptor antagonist with IC50 of 0.33 nM used in the management of nausea and vomiting induced by cancer chemotherapy. Uses: Antiemetics. Synonyms: Azasetron hydrochloride; Y 25130; Y-25130; Y25130. Y-25130 HCl. Grade: >98%. CAS No. 123040-16-4. Molecular formula: C17H20ClN3O3.HCl. Mole weight: 386.27. | |
| Azasetron, Hydrochloride (N-1-Azabicyclo[2.2.2]-oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-2H-1,4-benzoxazine-8-carboxamide, Hydrochloride) | A 5-HT3 receptor antagonist. Used as an antiemetic. Group: Biochemicals. Alternative Names: N-1-Azabicyclo[2.2.2]-oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-2H-1,4-benzoxazine-8-carboxamide, Hydrochloride. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Azasetron Impurity 2 | Azasetron Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6-chloro-4-methyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-8-carboxylic acid. CAS No. 123040-79-9. Molecular formula: C10H8ClNO4. Mole weight: 241.63. Catalog: APB123040799. |  |
| Azatadine | Azatadine is a new antihistamine acts as histamine for histamine H1- receptor inhibitor ( IC50 = 6.5 nM and 10 nM, respectively). Uses: Antihistaminic. Synonyms: 6,11-Dihydro-11-(1-methyl-4-piperidylidene)-5H-benzo[5,6]cyclohepta-[1,2-b]pyridine; 2-(1-methylpiperidin-4-ylidene)-4-azatricyclo[9.4.0.0³,?]pentadeca-1(15),3(8),4,6,11,13-hexaene. Grade: ≥98%. CAS No. 3964-81-6. Molecular formula: C20H22N2. Mole weight: 290.40. | |
| Azatadine dimaleate | Azatadine dimaleate. Group: Biochemicals. Alternative Names: 6, 11-Dihydro-11-(1-methyl-4-piperidinylidene)-5H-benzo[5, 6]cyclohepta[1, 2-b]pyridine; Azatadine Dimaleate. Grades: Highly Purified. CAS No. 3964-81-6,3978-86-7. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C20H22N2. US Biological Life Sciences. | Worldwide |
| Azatadine Dimaleate | Azatadine is an histamine and cholinergic inhibitor with IC50 of 6.5 nM and 10 nM, respectively. Uses: Histamine h1 antagonists. Synonyms: SCH10649; SCH 10649; SCH-10649. Grade: >98%. CAS No. 3978-86-7. Molecular formula: C20H22N2.2C4H4O4. Mole weight: 522.55. | |
| Azatadine Dimaleate. | Antihistaminic. Group: Biochemicals. Alternative Names: 6, 11-Dihydro-11-(1-methyl-4-piperidinylidene)-5H-benzo[5, 6]cyclohepta[1, 2-b]pyridine (2Z)-2-Butenedioate; 5- (4'-N-methyl piperidyl ide ne )-4-azo-10: 11-di hydrodibenzocyclohe ptene Dimaleate; Atoramin; Azatadine Maleate; Bonamid; Idulian; Optimine; Sch 10649; Trinalin; Zadine. Grades: Highly Purified. CAS No. 3978-86-7. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Azatadine maleate | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Azathioprine | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardspharma & vet compounds & metabolitespharma & vet compounds & metabolitesapi standardsbritish pharmacopoeiaeuropean pharmacopoeia (ph. eur.)pharmaceutical toxicologypharmacopoeial standards. Alternative Names: Azathioprine, Purine, 6-[(1-methyl-4-nitroimidazol-5-yl)thio]-, Muran, Azathropine, Azathioprine, BW 57-322, Azoran, 1H-Purine, 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-, Azathioprin, Imuran, Imurel, Imurek, 9H-Purine, 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-, Azamune, Azanin, NSC 39084, 6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine, 6-(1-Methyl-4-nitromidazol-5-ylthio)purine, Azothioprine, 6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine. | |
| Azathioprine | Azathioprine. Group: Biochemicals. Grades: Purified. CAS No. 446-86-6. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Azathioprine | Azathioprine is an immunosuppressive drug, inhibiting purine synthesis and GTP-binding protein Rac1 activation, used in the treatment of organ transplantation and autoimmune diseases. Uses: Antimetabolites. Synonyms: azathioprine; 446-86-6; Imuran; Azothioprine; Azathioprin; Azamun; Azanin; Azatioprin; Azasan; Ccucol; Imurek; Imurel; Muran; Azathiopurine; Rorasul; Azathioprinum; BW 57-322; NSC-39084; BW-57-322; Azatioprina; 6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine; NCI-C03474; NSC 39084; Methylnitroimidazolylmercaptopurine; 6-(1-Methyl-p-nitro-5-imidazolyl)-thiopurine; Azathioprinum [INN-Latin]; Azatioprina [INN-Spanish]; CCRIS 62; Imuran (TN); 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine; 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine; 6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine; HSDB 7084; 6-((1-Methyl-4-nitroimidazol-5-yl)thio)purine; Purine, 6-(1-methyl-4-nitro-5-imidazolylthio)-; 1H-Purine, 6-((1-methyl-4-nitro-1H-imidazol-5-yl)thio)-. Grade: >98%. CAS No. 446-86-6. Molecular formula: C9H7N7O2S. Mole weight: 277.26. | |
| Azathioprine | Azathioprine (BW 57-322) is an orally active immunosuppressive agent. Azathioprine can be converted in vivo to the active metabolite 6-mercaptopurine (6-MP). Azathioprine has myelosuppressive effects and induces apoptosis [1] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BW 57-322. CAS No. 446-86-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0256. | |
| Azathioprine-13C4 | Labeled Azathioprine. An immunosuppressive antimetabolite. Also active as disease modifying antirheumatic drug (DMARD). Group: Biochemicals. Alternative Names: 6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-purine-13C4; BW-57-322-13C4; NSC-39084-13C4; Azanin-13C4; Imuran-13C4; Imurek-13C4; Imurel-13C4; Zytrim-13C4. Grades: Highly Purified. CAS No. 1346600-71-2. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Azathioprine-[13C4] | Azathioprine-[13C4] is the labelled analogue of Azathioprine. Azathioprine is an immunosuppressive drug, inhibiting purine synthesis and GTP-binding protein Rac1 activation, used in the treatment of organ transplantation and autoimmune diseases. Synonyms: Azathioprine-13C4; 6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-purine-13C4; BW-57-322-13C4; NSC-39084-13C4; Azanin-13C4; Imuran-13C4; Imurek-13C4; Imurel-13C4; Zytrim-13C4. Grade: ≥96%; ≥98% atom 13C. CAS No. 1346600-71-2. Molecular formula: C5[13C]4H7N7O2S. Mole weight: 281.23. | |
| Azathioprine (6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-purine, BW-57-322, NSC-39084,. Azanin, Imuran, Imurek, Imurel, Zytrim) | An immunosuppressive antimetabolite. Also active as disease modifying antirheumatic drug (DMARD). Group: Biochemicals. Alternative Names: 6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-purine, BW-57-322, NSC-39084,Azanin, Imuran, Imurek, Imurel, Zytrim. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Azathioprine EP Impurity D | Azathioprine EP Impurity D is a metabolite of Azathioprine. Synonyms: 1-Methyl-4-nitro-5-thioimidazole; 1-Methyl-4-nitro-1H-imidazole-5-thiol; 5-Mercapto-1-methyl-4-nitroimidazole. Grade: > 95%. CAS No. 6339-54-4. Molecular formula: C4H5N3O2S. Mole weight: 159.17. | |
| Azathioprine EP Impurity E Sodium Salt | Azathioprine EP Impurity E Sodium Salt is a degradation product of Azathioprine. Synonyms: 5-Hydroxy-1-methyl-4-nitroimidazole Sodium Salt; 1-Methyl-4-nitro-1H-imidazol-5-ol Sodium Salt. Grade: > 95%. CAS No. 35681-68-6. Molecular formula: C4H4N3O3Na. Mole weight: 165.08. | |
| Azathioprine Impurity 16 | Azathioprine Impurity 16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 152529-79-8. Molecular formula: C14H14N4O5S. Mole weight: 350.35. Catalog: APB152529798. | |
| Azathioprine Impurity C | Azathioprine Impurity C is an impurity of 6-Mercaptopurine, which is an immunosuppressive drug used to treat leukemia. Synonyms: 6-Mercaptopurine Disulfide; 6,6'-Dithiodi-9H-purine; 6,6'-Dithiodi-purine; Bis(6-purinyl) disulfide; 1,2-Di(9H-purin-6-yl)disulfane; NSC 166569; NSC 77640. Grade: > 95%. CAS No. 49808-20-0. Molecular formula: C10H6N8S2. Mole weight: 302.34. | |
| Azathioprine Related Compound A | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Azathioprine Related Compound G | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| AzBTS | Spectrophotometric reagent for free chlorine. Group: Uv/visible (uv/vis) spectroscopy. Alternative Names: 2,2'-Azinobis(3-ethylbenzothiazoline-6-sulfonic Acid Ammonium Salt). | |
| AZD0095 | AZD0095 is a selective and orally active MCT4 inhibitor (IC50: 1.3 nM). AZD0095 effectively inhibits the tumor growth in NCI-H358 xenograft in combination with Cediranib (HY-10205)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2750001-23-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-148517. | |
| AZD0156 | AZD0156 is an orally active, potent and selective ataxia telangiectasia mutated (ATM) kinase inhibitor, used for cancer treatment. AZD0156 prevents DNA damage checkpoint activation, and disrupts DNA damage repair, inducing tumor cell apoptosis, and leading to cell death in ATM-overexpressing tumor cells. Uses: Protein kinase inhibitors. Synonyms: 8-[6-[3-(dimethylamino)propoxy]-3-pyridyl]-3-methyl-1-tetrahydropyran-4-yl-imidazo[4,5-c]quinolin-2-one; AZD0156; AZD-0156; AZD 0156. CAS No. 1821428-35-6. Molecular formula: C26H31N5O3. Mole weight: 461.56. | |
| AZD0156 | AZD0156 is a potent, selective and orally active ATM inhibitor with an IC 50 of 0.58 nM. AZD0156 inhibits the ATM -mediated signaling, prevents DNA damage checkpoint activation, disrupts DNA damage repair, and induces tumor cell apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1821428-35-6. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100016. | |
| AZD-0284 | AZD-0284 is a reverse agonist of the nuclear receptor (RORγ). AZD-0284 has the potential for the treatment of plaque psoriasis vulgaris and respiratory tract disorders. Synonyms: AZD0284; AZD 0284. CAS No. 2101291-07-8. Molecular formula: C21H18F6N2O5S. Mole weight: 524.43. | |
| AZD 0328 | AZD 0328 is a potent α7 NNR/5HT3 receptor agonist. AZD0328 led to a significant increase in cortical dopamine release in awake rodents and improved both conditioned response learning and memory retention in an object recognition task. Synonyms: (3R)-spiro[1-azabicyclo[2.2.2]octane-3,2'-3H-furo[2,3-b]pyridine]; AZD 0328; AZD-0328; AZD0328; UNII-2B218X5QIY; spiro(1-azabicyclo(2.2.2)octane-3,2'(3H)-furo(2,3-b)pyridine). Grade: >98%. CAS No. 220099-91-2. Molecular formula: C13H16N2O. Mole weight: 216.28. | |
| AZD0364 | AZD-0364 is a potent and selective ERK2 inhibitor, which has an IC50 value of 0.6 nM. AZD-0364 is measured in the A375 phospho-p90RSK assays with IC50s of 5.7 nM. AZD-0364 can inhibit the growth of a panel of cancer cell lines. The combination of Selumetinib and AZD-0364 ethanesulfonic acid results in a reduction in tumor growth. Synonyms: AZD-0364; AZD 0364; tizaterkib. Grade: ≥98%. CAS No. 2097416-76-5. Molecular formula: C24H24F2N8O2. Mole weight: 494.50. | |
| AZD0424 | AZD0424 is an orally bioavailable small molecule tyrosine kinase inhibitor. It targets both Abl and Src kinases with potential antineoplastic activity. It selectively inhibits both Src and Abl kinase activity and may result in the inhibition of tumor growth in susceptible tumor cells. Uses: Azd0424 has the inhibition of tumor growth in tumor cells. Synonyms: AZD 0424; AZD-0424; 1-(4-(2-((4-((6-chloro-[1,3]dioxolo[4,5-b]pyridin-7-yl)amino)-5-isopropoxyquinazolin-7-yl)oxy)ethyl)piperazin-1-yl)ethan-1-one; 7-(2-(4-Acetylpiperazin-1-yl)ethoxy)-4-(5-chloro-2,3-methylenedioxypyridin-4-ylamino)-5-isopropoxyquinazoline. Grade: 98%. CAS No. 692054-06-1. Molecular formula: C25H29ClN6O5. Mole weight: 528.99. | |
| AZD0780 | PCSK9-IN-12 is a heteroaryl compound. PCSK9-IN-12 has bind affinity for PCSK9 with a K d value of ?200 nM. PCSK9-IN-12 can be used for the research of cholesterol metabolism [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PCSK9-IN-12. CAS No. 2455427-91-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148673. | |
| AZD-0837 | AZD0837 is an oral direct thrombin inhibitor currently in clinical development for the prevention of stroke and systemic embolic events in patients with atrial fibrillation. Uses: Potassium channel antagonist. Synonyms: AZD0837; AZD-0837; AZD 0837; Atecegatran metoxil; Atecegatran fexenetil.1-((2R)-(3-chloro-5- (difluoromethoxy)phenyl)hydroxyacetyl)-N-((4-(imino(methoxyamino)methyl)phenyl)methyl)-, (2S)-2-Azetidinecarboxamide; (S)-1-((R)-2-(3-chloro-5-(difluoromethoxy)phenyl)-2-hydroxyacetyl)-N-(4-(N-methoxycarbamimidoyl)benzyl)azetidine-2-carboxamide. Grade: ≥95%. CAS No. 433937-93-0. Molecular formula: C22H23ClF2N4O5. Mole weight: 496.89. | |
| AZD1080 | AZD1080 is a brain-permeable GSK3 inhibitor with Ki values of 6.9 nM and 31 nM for GSK3α and GSK3β, respectively. Study showed that AZD1080 inhibited tau phosphorylation in cells. It also suppresses ovarian cancer cell proliferation, invasion, migration, and lamellipodia formation, and induces G1 arrest. Synonyms: AZD-1080; 2-hydroxy-3-[5-(morpholin-4-ylmethyl)pyridin-2-yl]-1H-indole-5-carbonitrile. Grade: >98%. CAS No. 612487-72-6. Molecular formula: C19H18N4O2. Mole weight: 334.37. | |
| AZD1080 | AZD1080 Inhibitor. Uses: Scientific use. Product Category: T1741. CAS No. 612487-72-6. |  |
| AZD1080 | AZD1080 is a potent and selective GSK3 inhibitor. AZD1080 inhibits recombinant human GSK3? and GSK3? with pKi (IC50) of 8.2 (6.9 nM) and 7.5 (31 nM), respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 612487-72-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13862. | |
| AZD1152-HQPA | Barasertib is a potent and highly selective inhibitor of AURKB with IC50 of 0.37 nM, acting via preventing the transfer of the phosphate group from the ATP molecule to AURKB substrates. The present study demonstrated for the first time, that AURKB inhibition interferes with early regeneration of SGs. Barasertib has been demonstrated that it is 3,700-fold greater selectivity than Aurora A. Synonyms: INH 34; AZD1152-HQPA; AZD2811. Grade: ≥98%. CAS No. 722544-51-6. Molecular formula: C26H30FN7O3. Mole weight: 507.56. | |
| AZD1152-HQPA | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| AZD1152, TFA Salt | An Aurora kinase inhibitor, used to treat patients with advanced solid tumors. Group: Biochemicals. Alternative Names: 3-[[7-[3-[Ethyl[2- (phosphonooxy) ethyl]amino]propoxy]-4-quinazolinyl]amino]-N- (3-fluorophenyl) -1H-pyrazole-5-acetamide Trifluoroacetic Acid Salt; Barasertib Trifluoroacetic Acid Salt; AZD-1152 Trifluoroacetic Acid Salt. Grades: Highly Purified. CAS No. 957881-03-7. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C??H??FN?O?P; x(C ?HF?O?), Molecular Weight: 587.54. US Biological Life Sciences. | Worldwide |
| AZD1208 | AZD1208 is an orally bioavailable, highly selective PIM kinases inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1204144-28-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-15604. | |
| AZD-1208 | AZD1208 is orally available, small molecule inhibitor of PIM kinases with potential antineoplastic activity. AZD1208 inhibits the activities of PIM1, PIM2 and PIM3 serine/threonine kinases, which may result in the interruption of the G1/S phase cell cycle transition. Synonyms: AZD1208; AZD 1208. Grade: 0.98. CAS No. 1204144-28-4. Molecular formula: C21H21N3O2S. Mole weight: 379.478. | |
| AZD1208 hydrochloride | AZD1208 (hydrochloride) is an orally bioavailable and highly selective PIM kinases inhibitor. CAS No. 1621866-96-3. Molecular formula: C21H22ClN3O2S. Mole weight: 415.94. | |
| AZD1283 | AZD1283 dose-dependently induced increases in blood flow and inhibition of ADP-induced platelet aggregation with antithrombotic ED50 values of 3.0 and 10 μg/kg/min, respectively. The doses that induced a larger than 3-fold increase in bleeding time were 33 and 100 μg/kg/min for 3 and 13, respectively. Thus, the therapeutic index (TI) was ≥10 for both compounds. On the basis of these data, compound 3 was progressed into human clinical trials as candidate drug AZD1283. Synonyms: AZD 1283; AZD-1283. Grade: 0.98. CAS No. 919351-41-0. Molecular formula: C23H26N4O5S. Mole weight: 470.544. | |
| AZD1283 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| AZD1305 | AZD1305 is a potassium channel and sodium channel antagonist. It can inhibit rapidly the activating delayed-rectifier potassium current, L-type calcium current, and inward sodium current. Phase II clinical trials for Arrhythmias, Atrial fibrillation, Atrial flutter and Left ventricular dysfunction were discontinued. Uses: Arrhythmias; atrial fibrillation; atrial flutter; left ventricular dysfunction. Synonyms: AZD-1305; AZD 1305; AZD1305; UNII-CZO834LXQM; UNII-CZO834LXQM; (2-(7-(2-(4-Cyano-2-fluorophenoxy)ethyl)-9-oxa-3,7-diazabicyclo(3.3.1)non-3-yl)ethyl)carbamic acid tert-butyl ester. Grade: 98%. CAS No. 872045-91-5. Molecular formula: C22H31FN4O4. Mole weight: 434.51. | |
| azd1390 | azd1390 Inhibitor. Uses: Scientific use. Product Category: T5175. CAS No. 2089288-03-7. | |
| AZD1390 | AZD1390 is a potent, highly selective, orally bioavailable, brain-penetrant ATM inhibitor with an IC 50 of 0.78 nM in cell [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2089288-03-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109566. | |
| AZD1390 | AZD1390 is a first-in-class, orally available and CNS penetrant ATM inhibitor with an IC50 of 0.78 nM in cells and >10,000-fold selectivity over closely related members of the PIKK family of enzymes and excellent selectivity across a broad panel of kinases. It can be used to cross the blood-brain barrier suitable for the treatment of intracranial malignancies. Synonyms: AZD-1390; AZD 1390. Grade: ≥98%. CAS No. 2089288-03-7. Molecular formula: C27H32FN5O2. Mole weight: 477.57. | |
| AZD1480 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| AZD1480 | AZD1480 is a novel ATP-competitive inhibitor of JAK1 and JAK2 with IC50 of 1.3nM and 0.26nM, respectively. Group: Biochemicals. Alternative Names: (S)-5-chloro-N2-(1-(5-fluoropyrimidin-2-yl)ethyl)-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| AZD-1480 | AZD-1480 is an ATP-competitive inhibitor of JAK1 and JAK2 with IC50s of 1.3 nM and <0.4?nM, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 935666-88-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10193. | |
| AZD-1480 | AZD1480 is an orally bioavailable inhibitor of Janus-associated kinase 2 (JAK2) with potential antineoplastic activity. AZD1480 inhibits JAK2 activation, leading to the inhibition of the JAK/STAT (signal transducer and activator of transcription) signaling including activation of STAT3. Synonyms: AZD1480; AZD-1480; AZD 1480. Grade: 0.98. CAS No. 935666-88-9. Molecular formula: C14H14ClFN8. Mole weight: 348.77. | |
| AZD1656 | AZD1656 is a potent, selective and orally active glucokinase activator with an EC 50 of 60 nM. AZD1656 has the potential for type 2 diabetes research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 919783-22-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15675. | |
| AZD 1656 | AZD 1656 is a potent and selective glucokinase (GK) activator with the potential for the treatment of type 2 diabetes. Synonyms: (S)-3-(5-(Azetidine-1-carbonyl)pyrazin-2-yloxy)-5-(1-methoxypropan-2-yloxy)-N-(5-methylpyrazin-2-yl)benzamide. Grade: 99%. CAS No. 919783-22-5. Molecular formula: C24H26N6O5. Mole weight: 478.50. | |
| AZD-1678 | AZD-1678 is a potent CCR4 receptor antagonist with a pIC50 of 8.6. Synonyms: 2,3-Dichloro-N-(5-fluoro-3-methoxy-2-pyrazinyl)benzenesulfonamide; Benzenesulfonamide, 2,3-dichloro-N-(5-fluoro-3-methoxy-2-pyrazinyl)-. Grade: ≥95%. CAS No. 942137-41-9. Molecular formula: C11H8Cl2FN3O3S. Mole weight: 352.17. | |
| AZD1979 | This active molecular is a MCHr1 (melanin concentrating hormone receptor 1) antagonist originated by AstraZeneca. AZD1979 has excellent DMPK properties and gave good effects on weight loss in animal model. In Jul 2014, AstraZeneca terminated a phase I trial in Obesity in healthy volunteers in USA after stopping criteria were reached. Uses: Obesity. Synonyms: AZD1979; AZD-1979; AZD 1979. (3-(4-((2-oxa-6-azaspiro[3.3]heptan-6-yl)methyl)phenoxy)azetidin-1-yl)(5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)methanone. Grade: 98%. CAS No. 1254035-84-1. Molecular formula: C25H26N4O5. Mole weight: 462.51. | |
| AZD1981 | AZD1981, as a potent antagonist in a disease relevant cell system, inhibits DK-PGD2-induced CD11b expression in human eosinophils with IC50 of 10 nM. Synonyms: AZD1981; AZD 1981; AZD-1981. Grade: 98%. CAS No. 802904-66-1. Molecular formula: C19H17ClN2O3S. Mole weight: 388.866. | |
| AZD1981 | AZD1981 is a potent and selective CRTh2 antagonist; displaces radio-labelled PGD2 from human recombinant DP2 with high potency (pIC50 = 8. Uses: Scientific research. Group: Signaling pathways. CAS No. 802904-66-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15950. | |
| AZD-2014 | AZD2014 is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity. AZD2014 inhibits the activity of mTOR, which may result in the induction of tumor cell apoptosis and a decrease in tumor cell proliferation. Synonyms: AZD2014, AZD-2014, AZD 2014, Vistusertib. Grade: 0.98. CAS No. 1009298-59-2. Molecular formula: C25H30N6O3. Mole weight: 462.554. | |
| AZD 2066 | AZD-2066 is a selective, orally active and blood-brain barrier-permeating mGluR5 antagonist. AZD 2066 activates the BDNF/trkB signaling pathway. AZD 2066 can be used in the research of neuropathic pain, major depressive disorder and gastroesophageal reflux disease [1] [2] [3] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 934282-55-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-110255. | |
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