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| Product | Description | |
|---|---|---|
| Aureoquinone | Aureoquinone is produced by the strain of Aureobasidium sp. The IC50 (μg/mL) for inhibiting the activity of protease, including trypsin, papain, thermophilic protease, collagenase and pound-protease are 11.4, 14.5, 17.8, 7.1, and 8.7 respectively. Synonyms: 2,5,7,8-tetrahydroxy-3,6-dimethylnaphthalene-1,4-dione. Molecular formula: C12H10O6. Mole weight: 250.20. |  |
| Aureothin | Aureothin is produced by the strain of Streptomyces thioluteus 4-A-1 and Streptomyces sp. 58. An unusual pyranone metabolite; has broad biological actions including antitumour, antimicrobial and insecticidal activities; a potent inhibitor of helicobacter pylori. Synonyms: Distacin; Mycolutein. Grade: >95% by HPLC. CAS No. 2825-00-5. Molecular formula: C29H26ClF3N2O6. Mole weight: 591. | |
| Aureothin | Aureothin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Aureothin, CTK8F7878, 2825-00-5, AG-E-90491, 4H-Pyran-4-one,2-methoxy-3,5-dimethyl-6-[(2R,4Z)-tetrahydro-4-[(2E)-2-methyl-3-(4-nitrophenyl)-2-propenylidene]-2-furanyl]-(9CI); 4H-Pyran-4-one, 2-methoxy-3,5-dimethyl-6-[tetrahydro-4-(b-methyl-p-nitrocinnamylidene)-2-furyl]-(6CI,7CI,8CI); 4H-Pyran-4-one, 2-methoxy-3,5-dimethyl-6-[tetrahydro-4-[2-methyl-3-(4-nitrophenyl)-2-propenylidene]-2-furanyl]-,[R-(Z,E)]-; (+)-(R)-Aureothin; (+)-Aureothin; Aureothin; Mycolutein; Strain 58substance. Product Category: Heterocyclic Organic Compound. CAS No. 2825-00-5. Molecular formula: C22H23NO6. Mole weight: 397.421120 [g/mol]. Purity: 0.96. IUPACName: 2-methoxy-3,5-dimethyl-6-[5-[2-methyl-3-(4-nitrophenyl)prop-2-enylidene]oxolan-2-yl]pyran-4-one. Density: 1.26g/cm³. Product ID: ACM2825005. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Aureothin (Distacin, Distacyne, Mycolutein, Antibiotic 74A'', Antibiotic JA 2814K) | Aureothin, an unusual pyranone metabolite, has broad biological actions including antitumor, antimicrobial and insecticidal activities. Aureothin acts by inhibition of oxidoreductase. More recently Aureothin has been shown to be a potent inhibitor of Helicobacter pylori. Group: Biochemicals. Alternative Names: Distacin, Distacyne, Mycolutein, Antibiotic 74A'', Antibiotic JA 2814K. Grades: Highly Purified. CAS No. 2825-00-5. Pack Sizes: 500ug. US Biological Life Sciences. |  Worldwide |
| Aureothin (Mycolutein, Distacin, JA 2814K, Antibiotic 74A, BRN 0058476) | Oxidoreductase inhibitor. Antitrypanosomal, antibacterial, antifungal, insecticidal and pesticidal. Antitumor compound. Group: Biochemicals. Grades: Highly Purified. CAS No. 2825-00-5. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| Aureothricin | Aureothricin. Group: Biochemicals. Alternative Names: Propionylpyrrothione. Grades: Highly Purified. CAS No. 574-95-8. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C9H10N2O2S2. US Biological Life Sciences. | Worldwide |
| Aureothricin | Aureothricin is produced by the strain of Streptomyces celluloflavus. It was active against gram-positive bacteria, negative bacteria and Mycobacterium, and intraperitoneal injection could inhibit the increase of ascites in transplanted mice with Aldrin ascites carcinoma. Synonyms: Propionylpyrrothione; Farcinin. Grade: >98% by HPLC. CAS No. 574-95-8. Molecular formula: C9H10N2O2S2. Mole weight: 242.32. | |
| Aureothricin (Propionylpyrrothione, Farcinicin, N-(4-Methyl-5-oxo-4,5-dihydro-[1,2]dithiolo[4,3-b]pyrrol-6-yl)propionamide) | Antibiotic. Active against Gram-positive and Gram-negative bacteria, yeast, filamentous fungi, protozoa and insects. Potent bacterial and yeast RNA polymerases inhibitor. Inhibitor of fungal mannan and glucan formation. Similar to thiolutin. Antitumor compound. Group: Biochemicals. Grades: Highly Purified. CAS No. 574-95-8. Pack Sizes: 500ug, 1mg. US Biological Life Sciences. | Worldwide |
| Aureothricin (Propionylpyrrothione, Farcinin) | Aureothricin is an antibiotic first described by Umezawa and co-workers in Japan in 1949. Resurgent interest in this class of microbial metabolites was stimulated by the discovery of their selective antitumor activity. Aureothricin is a more hydrophobic analogue of thiolutin but has received only limited attention. Members of this class, notably, thiolutin, have been shown to potent inhibitors of bacterial and yeast RNA polymerases and inhibitors of mannan and glucan formation in fungi. Studies have shown that thiolutin inhibits tumor cell-induced angiogenesis in vivo. Group: Biochemicals. Alternative Names: Propionylpyrrothione, Farcinin. Grades: Highly Purified. CAS No. 574-95-8. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Auresine | recombinant, lyophilized powder. Group: Fluorescence/luminescence spectroscopy. |  |
| Aureusidin | Aureusidin. Group: Biochemicals. Alternative Names: (2Z) -2-[ (3, 4-dihydroxyphenyl) methylene]-4, 6-dihydroxy-3 (2H) -benzofuranone; Cernuin. Grades: Highly Purified. CAS No. 38216-54-5. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C15H10O6. US Biological Life Sciences. | Worldwide |
| aureusidin synthase | A copper-containing glycoprotein that plays a key role in the yellow coloration of flowers such as Antirrhinum majus (snapdragon). The enzyme is a homologue of plant polyphenol oxidase and catalyses two separate chemical transformations, i.e. 3-hydroxylation and oxidative cyclization (2',-dehydrogenation). H2O2 activates reaction (1) but inhibits reaction (2). Originally considered to act on the phenol but now thought to act mainly on the 4'-O-β-D-glucoside in vivo. Group: Enzymes. Synonyms: AmAS1. Enzyme Commission Number: EC 1.21.3.6. CAS No. 320784-48-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1253; aureusidin synthase; EC 1.21.3.6; 320784-48-3; AmAS1. Cat No: EXWM-1253. |  |
| Aureusimine B | It is an inhibitor of the protease Calpain produced by the strain of Streptomyces sp. SC433. It is a small molecular weight monoketopiperazine formed non-ribosomally by the fusion of phenylalanine and valin. Synonyms: Phevalin; 3-(1-Methylethyl)-6-(phenylmethyl)-2(1H)-pyrazinone; 6-Benzyl-3-isopropylpyrazin-2-one. Grade: >95% by HPLC. CAS No. 170713-71-0. Molecular formula: C14H16N2O. Mole weight: 228.29. | |
| Auriclosene | Auriclosene is a potent and Broad spectrum antimicrobial agent. It is highly effective in in vitro studies against multi-drug resistant bacteria including Methicillin-resistant Staphylococcus aureus (MRSA) and Vancomycin-resistant Enterococcus (VRE). Phase III clinical trials for the treatment of Impetigo are on-going. Uses: Impetigo. Synonyms: NVC-422; NVC 422; NVC422; CD07223; CD-07223; CD 07223; Auriclosene. UNII-BKR7Y95229; 2-(dichloroamino)-2-methylpropane-1-sulfonic acid. Grade: 98%. CAS No. 846056-87-9. Molecular formula: C4H9Cl2NO3S. Mole weight: 222.08. | |
| Auric sodium Chloride | Auric sodium Chloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Sodium tetrachloroaurate. Product Category: Gold series of catalysts. Appearance: yellow crystals. CAS No. 15189-51-2. Molecular formula: NaAuCl4·2H2O. Mole weight: 397.8. Purity: Au 48.0%. Density: g/cm³. Product ID: ACM15189512. Alfa Chemistry ISO 9001:2015 Certified. | |
| Auriculasin | Auriculasin is a flavonoid derivative isolated from the herbs of Derris robusta. Synonyms: Cudraisoflavone A. Grade: 96%. CAS No. 60297-37-2. Molecular formula: C25H24O6. Mole weight: 420.5. | |
| Aurin | Aurin. Group: Biochemicals. Alternative Names: p-Rosolic acid; 4-[Bis (4-hydroxyphenyl) methylene]-2, 5-cyclohexadienone. Grades: Highly Purified. CAS No. 603-45-2. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C19H14O3. US Biological Life Sciences. | Worldwide |
| Aurintricarboxylic acid | Aurintricarboxylic acid acts as a histological dye and an insulin-like growth factor receptor 1 antagonist. Synonyms: 1,4-cyclohexadiene-1-carboxylic acid, 3-(bis(3-carboxy-4-hydroxyphenyl)methylen; aluminon free acid. Grade: 95%. CAS No. 4431-00-9. Molecular formula: C22H14O9. Mole weight: 422.34. | |
| Aurintricarboxylic acid | practical grade, ?85% (titration), powder. Group: Fluorescence/luminescence spectroscopy. | |
| Aurintricarboxylic acid | 5g Pack Size. Group: Biochemicals, Building Blocks, Organics. Formula: C22H14O9. CAS No. 4431-00-9. Prepack ID 21152979-5g. Molecular Weight 422.34. See USA prepack pricing. |  |
| Aurintricarboxylic acid | Aurintricarboxylic acid is a nanomolar-potency, allosteric antagonist with selectivity towards αβ-methylene-ATP-sensitive P2X1Rs and P2X3Rs , with IC 50 s of 8.6 nM and 72.9 nM for rP2X1R and rP2X3R, respectively [1]. Aurintricarboxylic acid is a potent anti-influenza agent by directly inhibiting the neuraminidase [2]. Aurintricarboxylic acid is an inhibitor of topoisomerase II and apoptosis [3]. Aurintricarboxylic acid is a selective inhibitor of the TWEAK-Fn14 signaling pathway [4]. Aurintricarboxylic acid also acts as a cystathionine-lyase (CSE) inhibitor with an IC 50 of 0.6 μM [5]. Aurintricarboxylic acid is a modifier of miRNAs that regulate miRNA function, with an IC 50 of 0.47 μM [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4431-00-9. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-122575. |  |
| Aurintricarboxylic Acid | Aurintricarboxylic acid is a nanomolar-potency, allosteric antagonist with selectivity towards αβ-methylene-ATP-sensitive P2X1Rs and P2X3Rs, with IC50s of 8.6 nM and 72.9 nM for rP2X1R and rP2X3R, respectively. Aurintricarboxylic acid is a potent anti-influenza agent by directly inhibiting the neuraminidase. Aurintricarboxylic acid is an inhibitor of topoisomerase II and apoptosis. Aurintricarboxylic acid is a selective inhibitor of the TWEAK-Fn14 signaling pathway. Aurintricarboxylic acid also acts as a cystathionine-lyase (CSE) inhibitor with an IC50 of 0.6 μM. Aurintricarboxylic acid is a modifier of miRNAs that regulate miRNA function, with an IC50 of 0.47 μM. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Ata. Product Category: Inhibitors. Appearance: Powder. CAS No. 4431-00-9. Molecular formula: C22H14O9. Mole weight: 422.34. Purity: 0.85. Canonical SMILES: C1=CC(=C(C=C1C(=C2C=CC(=O)C(=C2)C(=O)O)C3=CC(=C(C=C3)O)C(=O)O)C(=O)O)O. Product ID: ACM4431009. Alfa Chemistry ISO 9001:2015 Certified. | |
| Aurintricarboxylic acid ammonium salt (Aluminon) | 100g Pack Size. Group: Analytical Reagents, Biochemicals, Building Blocks, Organics. Formula: C22H23N3O9. CAS No. 569-58-4. Prepack ID 28596801-100g. Molecular Weight 473.43. See USA prepack pricing. | |
| Auristatin E | Auristatin E is a synthetic analog of dolastatin 10. Auristatin E is a highly potent antimitotic agent.Auristatin E inhibits tubulin polymerization. Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity. Uses: Adcs cytotoxin. Synonyms: Auristatin E. Grade: ≥96.0% (HPLC). CAS No. 160800-57-7. Molecular formula: C40H69N5O7. Mole weight: 732.01. | |
| Auristatin F | Auristatin F, a synthetic analog of dolastatin 10, is a cytotoxic tubulin modifier with potent and selective antitumor activity. It is an MMAF analog and cytotoxin in Antibody-drug conjugates. Uses: Adcs cytotoxin. Synonyms: N,N-Dimethyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-L-phenylalanine; L-Valinamide, N,N-dimethyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-; N,N-Dimethyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S)-1-carboxy-2-phenylethyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}-3-methoxy-5-methyl-1-oxo-4-heptanyl]-N-methyl-L-valinamide. Grade: ≥97% by HPLC. CAS No. 163768-50-1. Molecular formula: C40H67N5O8. Mole weight: 745.99. | |
| Aurkin A | Aurkin A is an allosteric inhibitor for the interaction between Aurora A Kinase (also known also Aurka) and TPX2, through targeting the TPX2 binding sites with Kd of 3.77 ?M. Aurkin A can disrupt polyploidy induced by Alisertib (HY-10971) and increase apoptosis of tumor cells. Aurkin A can be used in research on mitosis and cancer[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1534060-58-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125956. | |
| Aurodox | It is produced by the strain of Streptomyces goldiniensis var. goldiniensis. Aurodox is a polyketide antibiotic originally isolated from S. goldiniensis, which inhibits bacterial protein biosynthesis by interrupting the functional cycle of Elongation Factor-Tu (EF-Tu). Aurodox is a type 3 secretion system (T3SS) inhibitor and growth promotor in poultry. It is active against Gram-positive bacteria, including B. megaterium, B. anthracis, and M. hominis (MICs = 0.06, 0.6, and 3-10 μg/ml, respectively). Synonyms: Antibiotic X 5108; Goldinodox; Goldinomycin; 1-methyl-Mocimycin; Benzamide; CYT11387. Grade: ≥95%. CAS No. 12704-90-4. Molecular formula: C44H62N2O12. Mole weight: 810.97. | |
| Aurodox (1-Methylmocimycin, Antibiotic X 5108, Goldinodox, Goldinomycin, NSC 233989) | Antibiotic. Protein biosynthesis inhibitor by binding to elongation factor Tu (EF-Tu). Type 3 secretion system (T3SS) inhibitor. Growth promotor in poultry. Group: Biochemicals. Grades: Highly Purified. CAS No. 12704-90-4. Pack Sizes: 1mg, 2.5mg. US Biological Life Sciences. | Worldwide |
| Aurodox (1-Methylmocimycin, Antibiotic X 5108, Goldinodox, Goldinomycin, NSC 233989, Benzamide, CYT11387) | Isolated from Streptomyces sp. K06-0806. Protein biosynthesis inhibitor by binding to elongation factor Tu (EF-Tu). Effective against streptococcus pyogenes infections. It may promote growth in poultry. Group: Biochemicals. Grades: Highly Purified. CAS No. 12704-90-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Aurofusarin | Aurofusarin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Aurofusarin, (7,7-Bi-4H-naphtho(2,3-b)pyran)-4,4,6,6,9,9-hexone, 5,5-dihydroxy-8,8-dimethoxy-2,2-dimethyl-, 13191-64-5, Airofusorin, AC1Q6OJ7, SureCN5578918, KST-1A1369, AC1L4100, AR-1A7077, NSC244432, NSC-244432, A807820, 5-hydroxy-7-(5-hydroxy-8-methoxy-2-methyl-4,6,9-trioxo-7-benzo[g][1]benzopyranyl)-8-methoxy-2-methylbenzo[g][1]benzopyran-4,6,9-trione, 5-hydroxy-7-(5-hydroxy-8-methoxy-2-methyl-4,6,9-trioxobenzo[g]chromen-7-yl)-8-methoxy-2-methylbenzo[g]chromene-4,6,9-trione, 8-methoxy-7-[8-methoxy-2-methyl-5-oxidanyl-4,6,9-tris(oxidanylidene)benzo[g]chromen-7-yl]-2-methyl-5-oxidanyl-benzo[g]chromene-4,6,9-trione. Product Category: Heterocyclic Organic Compound. CAS No. 13191-64-5. Molecular formula: C30H18O12. Mole weight: 570.456720 [g/mol]. Purity: 0.96. IUPACName: 5-hydroxy-7-(5-hydroxy-8-methoxy-2-methyl-4,6,9-trioxobenzo[g]chromen-7-yl)-8-methoxy-2-methylbenzo[g]chromene-4,6,9-trione. Density: 1.69g/cm³. Product ID: ACM13191645. Alfa Chemistry ISO 9001:2015 Certified. | |
| Aurofusarin | Dimeric naphthoquinone. Antibiotic activity. Mycotoxin. Toxic against mammalians and avian species. Analytical standard in food industry. Group: Biochemicals. Alternative Names: 4H-Naphtho[2,3-b]pyran, bimol. deriv.; 5,5-Dihydroxy-8,8-dimethoxy-2,2-dimethyl[7,7-bi-4H-naphtho[2,3-b]pyran]-4,4,6,6,9,9-hexone; Aurofusarin; NSC 244432. Grades: Highly Purified. CAS No. 13191-64-5. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Auroglaucin | It is produced by the strain of Aspergillus spp. Synonyms: 2-[(1E,3E,5E)-1,3,5-Heptatrienyl]-3,6-dihydroxy-5-(3-methyl-2-butenyl)benzaldehyde; Auroglaucine; 2-((1E,3E,5E)-hepta-1,3,5-trien-1-yl)-3,6-dihydroxy-5-(3-methylbut-2-en-1-yl)benzaldehyde. CAS No. 41451-81-4. Molecular formula: C19H22O3. Mole weight: 298.38. | |
| Aurora 17729 | Aurora 17729. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AURORA 17729. Product Category: Heterocyclic Organic Compound. CAS No. 71082-34-3. Molecular formula: C13H13NO4. Mole weight: 247.25. Product ID: ACM71082343. Alfa Chemistry ISO 9001:2015 Certified. Categories: Ethyl 4-hydroxy-8-methoxyquinoline-3-carboxylate, Aurora (1779 ship). | |
| AURORA 19959 | AURORA 19959. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AURORA 19959;OTAVA-BB BB7014740329;3-CHLORO-7-HYDROXY-4H-CHROMEN-4-ONE;OTAVA-BB 7014740329. Product Category: Heterocyclic Organic Compound. CAS No. 685848-25-3. Molecular formula: C9H5ClO3. Mole weight: 196.59. Product ID: ACM685848253. Alfa Chemistry ISO 9001:2015 Certified. | |
| Aurora 2035 | Aurora 2035. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Maybridge1_002371, DivK1c_001123, HMS548D17, ISWHPQMMRBTZOY-UHFFFAOYSA-, MolPort-000-419-158, MolPort-000-754-331, MolPort-003-912-933, NSC228504, CID313644, ZINC03850598, CDS1_000083, BAS 00405087, AB00123098-02, 5-(3,4-Dimethoxy-benzylidene)-pyrimidine-2,4,6-trione, A2823/0119215, 66386-22-9, InChI=1/C13H12N2O5/c1-19-9-4-3-7(6-10(9)20-2)5-8-11(16)14-13(18)15-12(8)17/h3-6H,1-2H3,(H2,14,15,16,17,18). Product Category: Heterocyclic Organic Compound. CAS No. 66386-22-9. Molecular formula: C13H12N2O5. Mole weight: 276.2448. Purity: 0.96. IUPACName: 5-[(3,4-dimethoxyphenyl)methylidene]-1,3-diazinane-2,4,6-trione. Canonical SMILES: COC1=C(C=C(C=C1)C=C2C(=O)NC(=O)NC2=O)OC. Product ID: ACM66386229. Alfa Chemistry ISO 9001:2015 Certified. | |
| Aurora 3, Control peptide (STK13, Serine Threonine Kinase 13, Aurora C, AIE2, AIK3, Aurora Related Kinase 3, Aurora/IPL1-like) | A synthetic peptide derived from the N-terminus of the human Aurora-3 protein. Group: Molecular Biology. Grades: Purified. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
| Aurora 6910 | Aurora 6910. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-(3,4,5-Trimethoxy-benzoyl)-4-chlor-anilin; 3.4.5-Trimethoxy-benzoesaeure-<4- | |
| AURORA A, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Aurora A Inhibitor I | Aurora A Inhibitor I is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM. It is 1000-fold more selective for Aurora A than Aurora B. Synonyms: TC-S 7010; TC S 7010; TCS7010. Grade: >98%. CAS No. 1158838-45-9. Molecular formula: C31H31ClFN7O2. Mole weight: 588.07. | |
| Aurora-A Inhibitor I | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Aurora A inhibitor II | Aurora A inhibitor II is a potent and selective inhibitor of Aurora A kinase (AurA; IC50 = 4.3 nM). Synonyms: 4-[[2-[[4-[2-(4-acetyl-1-piperazinyl)-2-oxoethyl]phenyl]amino]-5-fluoro-4-pyrimidinyl]amino]-N-(2-chlorophenyl)-Benzamide. Grade: 99%. CAS No. 1158838-43-7. Molecular formula: C31H29ClFN7O3. Mole weight: 602.06. | |
| AURORA B, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Aurora B inhibitor 1 | Aurora B inhibitor 1 is an Aurora B (Aurora-1) inhibitor. It also inhibits JAK3 and JAK2. Synonyms: Methanone, (5-chloro-2-fluorophenyl)?[(3S)?-3-[[4-(3-cyclopropyl-3-fluoro-1-azetidinyl)?-6-[(5-methyl-1H-pyrazol-3-yl)?amino]?-2-pyrimidinyl]?oxy]?-1-pyrrolidinyl]?-. CAS No. 937276-52-3. Molecular formula: C25H26ClF2N7O2. Mole weight: 529.97. | |
| AURORA C, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Aurora inhibitor 1 | Aurora inhibitor 1 is a potent Aurora inhibitor (IC50 = 4 nM and 13 nM for Aurora A and Aurora B kinase). CAS No. 2227019-45-4. Molecular formula: C23H25N9S. Mole weight: 459.57. | |
| Aurora Kinase A active human | recombinant, expressed in baculovirus infected Sf9 cells, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| Aurora Kinase A active human, Recombinant | Aurora A kinase also known as serine/threonine-protein kinase 6 is an enzyme that in humans is encoded by the AURKA gene. Aurora A is a member of a family of mitotic serine/threonine kinases. It is implicated with important processes during mitosis and meiosis whose proper function is integral for healthy cell proliferation. Aurora A is activated by one or more phosphorylations and its activity peaks during the G2 phase to M phase transition in the cell cycle. Human aurora kinase a (genbank accession no. nm_003600), amino acids 2-403 with n-terminal his6-tag, mw=50 kda, expressed in a baculovirus infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: Aurora Kinase A; Aurora A kinase; serine/threonine-protein kinase 6; AURKA; AIK; ARK1; AURA; AURORA2; BTAK; PPP1R47; STK15; STK6; STK7. Purity: > 90% (SDS-PAGE). ARK1. Mole weight: mol wt 50 kDa. Activity: ~17,000 units/mg protein. Form: aqueous solution. Source: baculovirus infected Sf9 cells. Species: Human. Aurora Kinase A; Aurora A kinase; serine/threonine-protein kinase 6; AURKA; AIK; ARK1; AURA; AURORA2; BTAK; PPP1R47; STK15; STK6; STK7. Pack: Minimum 50 ng protein/vial by Bradford. Cat No: NATE-0087. | |
| Aurora kinase inhibitor-2 | Aurora kinase inhibitor-2 is a selective and ATP-competitive Aurora kinase inhibitor with IC 50 s of 310 nM and 240 nM for Aurora A and Aurora B , respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 331770-21-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112355. | |
| Aurora Kinase Inhibitor II | The Aurora kinases are a family of serine/threonine kinases that are key regulators of mitosis and cytokinesis. Aurora kinase inhibitor II is a cell-permeable anilinoquinazoline that blocks the activity of Aurora A with IC50 of 0.39 μM. This compound has the ability to permeate the cell and is involved in the regulation of the cell cycle, particularly cell division. This compound has the ability to permeate the cell and is involved in the regulation of the cell cycle, particularly cell division. Synonyms: 4-(4?-Benzamidoanilino)-6,7-dimethoxyquinazoline. Grade: ≥98%. CAS No. 331770-21-9. Molecular formula: C23H20N4O3. Mole weight: 400.4. | |
| Aurora Kinase Inhibitor III | Aurora kinase inhibitor III is a potent ATP-competitive aurora related kinase inhibitor with IC50 of 42 nM. Aurora kinase inhibitor III is a cell-permeable, 2,4-dianilinopyrimidine compound which has been used to study a variety of tumor types. It is selective for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR (IC50s = 386, 3,550, 591, 1,980, 2,510, 887, and >10,000 nM, respectively). Aurora kinase protein levels are elevated in c-myc-driven B-cell lymphomas in both mice and humans. Study of the inhibition of Aurora kinase proteins could lead to potential treatments for malignancies. Synonyms: Aurora Kinase Inhibitor III; AKI-7169; AKI 7169; AKI7169. Grade: ≥98%. CAS No. 879127-16-9. Molecular formula: C21H18F3N5O. Mole weight: 413.4. | |
| Aurora Kinase Inhibitor VI, ZM447439 (4-(4-(N-Benzoylamino)anilino)-6- methoxy-7- (3- (1-morpholino) propoxy) quinazoline) | A cell-permeable quinazoline compound that targets the ATP binding pocket and an adjacent cleft and acts as a potent and reversible inhibitor of Aurora A and Aurora B (IC50=110 and 130nM, respectively) with moderate to excellent selectivity among closely related 16-kinase panel (IC50=0.88, 1.03 and 1.79uM for Lck, Src and MEK1, respectively, and IC50>10uM for Cdk1/2/4, Plk1, Chk1). Blocks phosphorylation of Histone H3-Ser10 in Xenopus cycling egg extracts at 20uM, and reduces mitotic spindle assembly. Shown to repress kinetochore localization of BubR1, Cenp-E, and Mad2, and arrest the growth of proliferating tumor cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 331771-20-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Aurothioglucose | Aurothioglucose is used in the treatment of rheumatoid arthritis and psoriasis. Synonyms: AUROTHIOGLUCOSE; Solganal; 12192-57-3; Gold thioglucose; Aurothioglucose 80%; Aurothioglucose hydrate; Solganol; Gold(1+); 3,4,5-trihydroxy-6-(hydroxymethyl)oxane-2-thiolate; gold(1+); (3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxane-2-thiolate; DTXSID5046013; NCGC00096015-01; Spectrum_001866; NSC-759601; KBioSS_002383; SPECTRUM1500132; DTXCID3026013; KBio2_002379; KBio2_004947; KBio2_007515; HMS2091K17; Pharmakon1600-01500132; Tox21_111549; NSC759601; CCG-213700; PD057378; SBI-0206666.P002; CAS-12192-57-3; AB00053375_02; SR-05000001568; SR-05000001568-1; BRD-A89825407-001-01-8. Grade: >98%. CAS No. 12192-57-3. Molecular formula: C6H11AuO5S. Mole weight: 392.18. | |
| Aurothioglucose | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Aurothioglucose | Aurothioglucose (Gold thioglucose), containing monovalent gold ion, is a potent active-site inhibitor of TrxR1 (thioredoxin reductase 1), with an IC 50 of 65 nM. Aurothioglucose inhibits the DNA binding of NF-κB in vitro. Aurothioglucose shows anti-HIV and anti-rheumatic activities [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Gold thioglucose. CAS No. 12192-57-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-A0068. | |
| Aurothioglucose-13C6 | Aurothioglucose-13C6 is a labelled analogue of Aurothioglucose, which is used in the treatment of rheumatoid arthritis and psoriasis. Synonyms: [1-(thio-κS)-D-Glucopyranosato-κO2]-gold-13C6; 1-thio-D-Glucose S-gold Derivative-13C6; (1-thio-D-Glucopyranosato)-Gold-13C6; (1-thio-D-Glucopyranosato-O2,S1)gold-13C6; 1-thio-D-Glucopyranose Gold Complex-13C6; (D-Glucopyranosylthio)gold-13C6; Aureotan-13C6; Auromyose-13C6; Aurothioglucose-13C6; Aurumine-13C6; Authron-13C6; Brenol-13C6; 1-thio-Glucose Gold Salt (1:1)-13C6; Glysanol B-13C6; Gold Thioglucose-13C6; (D-Glucopyranosylthio)gold-13C6; Oronol-13C6; Solganal-13C6; Solganal B-13C6. Grade: 70% by HPLC; 98.7% atom 13C. Molecular formula: [13C]6H11AuO5S. Mole weight: 398.14. | |
| Aurothioglucose hydrate | ?96% (titration). Group: Fluorescence/luminescence spectroscopy. | |
| Aurothioglucose USP | (a-D-glucopyranosylthio)gold. Grades: USP. CAS No. 12192-57-3. Product ID: 8-01219. Molecular formula: C6H11AuO5S. Mole weight: 392.18. Properties: low Pd, low hydroxyl value. |  |
| Aurothiomalate sodium | Aurothiomalate sodium is a potent and selective oncogenic PKC Ι signaling inhibitor. Aurothiomalate sodium inhibits tumor cell proliferation and not cell apoptosis. Aurothiomalate sodium is a potent thioredoxin reductase (TrxR) inhibitor. Aurothiomalate sodium, an anti-rheumatoid agent, exhibits potent anti-tumor activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 12244-57-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106381. | |
| Australian Chemical Suppliers | Australian Chemical Suppliers Database | Australian Chemical Suppliers Australia |
| Australifungin | Australifungin is produced by the strain of Sporormiella australis. As an inhibitor of Shinganine n-acyl-transferase, it has strong antifungal activity, with MIC of 0.015-0.5 μg/mL for candida, cryptococcus neoforme, saccharomyces cerescens and other fungi, and 0.125 ~ 1μg/ mL for aspergillus. Australian fennetol has a low antifungal effect. Molecular formula: C23H36O6. Mole weight: 408.53. | |
| AUT1 | AUT1 is a modulator of recombinant human Kv3 channel. Synonyms: AUT-1; AUT 1. Grade: 98% by HPLC. CAS No. 1311136-84-1. Molecular formula: C18H19N3O4. Mole weight: 341.4. | |
| AUT1 | AUT1 is a recombinant human Kv3 channel modulator. AUT1 modulates Kv3.1b and Kv3.2a channels in human recombinant with pEC50 values of 5.33 and 5.31 ?M, respectively. AUT1 can be used for the research of disorders associated with dysfunction of inhibitory feedback in corticolimbic circuits, such as schizophrenia[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1311136-84-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-117639. | |
| AUTAC1 | AUTAC1 is a MetAP2-targeting autophagy-mediated degrader (AUTAC), which contains a degradation tag and a warhead to provide target specificity. It is composed of an FBnG (p-Fluorobenzyl Guanine) and a Fumagillol moiety, with the Fumagillol binding covalently to MetAP2. AUTAC1 has potential anticancer activity as it can degrade MetAP2 and FKBP12 proteins and is used in the synthesis of PROTACs. This compound represents a novel targeted-clearance strategy that harnesses the autophagy-lysosome pathway for the degradation of specific proteins, expanding the scope of targeted protein degradation beyond the limitations of proteasomal clearance. Synonyms: (3R,4S,5S,6R)-5-Methoxy-4-((2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl)-1-oxaspiro[2.5]octan-6-yl ((R)-4-(((2-amino-9-(4-fluorobenzyl)-6-oxo-6,9-dihydro-1H-purin-8-yl)thio)methyl)-2,5-dioxo-10,13,16-trioxa-3,6-diazanonadecan-19-yl)carbamate; 6,9,12-Trioxa-2,16,19-triazaheneicosanoic acid, 18-[[[2-amino-9-[(4-fluorophenyl)methyl]-6,9-dihydro-6-oxo-1H-purin-8-yl]thio]methyl]-17,20-dioxo-. Grade: ≥95%. CAS No. 2241669-09-8. Molecular formula: C44H63FN8O11S. Mole weight: 931.08. | |
| Au TiO2 Core Shell Nanoparticles | Au TiO2 Core Shell Nanoparticles. Group: Core shell nanoparticles. 99.9%. |  |
| Au TiO2 Core-Shell Nanoparticles | Au TiO2 Core-Shell Nanoparticles. Group: Core shell nanoparticles. 99.9%. | |
| Autocamtide 2 | Autocamtide 2 is a highly selective synthetic peptide substrate of calcium/calmodulin-dependent protein kinase II (CaMKII). It can be used in the CaMKII activity assay. Synonyms: Autocamtide II; H-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Thr-Val-Asp-Ala-Leu-OH; L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-arginyl-L-arginyl-L-glutaminyl-L-alpha-glutamyl-L-threonyl-L-valyl-L-alpha-aspartyl-L-alanyl-L-leucine. Grade: ≥95%. CAS No. 129198-88-5. Molecular formula: C65H118N22O20. Mole weight: 1527.77. | |
| Autocamtide 2 | Autocamtide 2 is a highly selective peptide substrate of calcium/calmodulin-dependent protein kinase II ( CaMKII ). It can be used in the CaMKII activity assay. Uses: Scientific research. Group: Peptides. Alternative Names: Autocamtide II. CAS No. 129198-88-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P0225. | |
| Autocamtide 2, amide | Autocamtide 2, amide is a highly selective synthetic peptide substrate of calcium/calmodulin-dependent protein kinase II (CaMKII). It can be used in the CaMKII activity assay. Synonyms: Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Thr-Val-Asp-Ala-Leu-NH2. Grade: ≥95%. Molecular formula: C65H119N23O19. Mole weight: 1526.79. | |
| Autocamtide 2-related inhibitory peptide | ?97% (HPLC), lyophilized powder. Group: Fluorescence/luminescence spectroscopy. | |
| Autocamtide-2-related inhibitory peptide | Autocamtide-2-related inhibitory peptide. Group: Biochemicals. Grades: Purified. CAS No. 167114-91-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
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