American Chemical Suppliers
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Product | Description | |
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BMS-188494 Quick inquiry Where to buy Suppliers range | BMS-188494 is the prodrug of BMS-187745, a squalene synthase inhibitor used as an anticholesterol drug. Synonyms: 1-[bis (2, 2-dimethylpropanoyloxymethoxy) phosphoryl]-4- (3-phenoxyphenyl) butane-1-sulfonic acid; BMS-188494; BMS 188494; BMS188494; UNII-F4W2579G7P. Grades: >98%. CAS No. 191866-32-7. Molecular formula: C28H39O11PS. Mole weight: 614.645. | |
BMS 188745 potassium salt Quick inquiry Where to buy Suppliers range | BMS 188745 potassium salt. Group: Biochemicals. Alternative Names: (a-S) -3-Phenoxy-a-phosphono Benzene butanesulfonic acid tripotassium salt. Grades: Highly Purified. CAS No. 157126-15-3. Pack Sizes: 10mg. Molecular Formula: C16H16K3O7PS. US Biological Life Sciences. | Worldwide |
BMS 191011 Quick inquiry Where to buy Suppliers range | BMS 191011. Group: Biochemicals. Grades: Purified. CAS No. 202821-81-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
BMS 191011 Quick inquiry Where to buy Suppliers range | BMS 191011 is a potent opener of the large-conductance, Ca2+-activated potassium (maxi-K) channel. It is neuroprotectant in two distinct animal models of stroke (MCAO in the SHR rat and a normotensive model of focal stroke). Synonyms: 3-[(5-chloro-2-hydroxyphenyl)methyl]-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazol-2-one; BMS-191011; BMS 191011; BMS191011; UNII-LW7MXS978N; Bms-a. Grades: >99 %. CAS No. 202821-81-6. Molecular formula: C16H10ClF3N3O3. Mole weight: 370.71. | |
BMS-191095 Quick inquiry Where to buy Suppliers range | BMS-191095 is an activators that has selective effects on mitochondrial ATP-sensitive potassium (mitoKATP) channels. in vitro: induces mitochondrial-depolarization and vasodilation. Synonyms: (3R,4S)-4-[4-chloro-N-(1H-imidazol-2-ylmethyl)anilino]-3-hydroxy-2,2-dimethyl-3,4-dihydrochromene-6-carbonitrileBMS-191095; BMS 191095; BMS191095CHEMBL11594SCHEMBL8896325ZI NC3821976BDBM50409914. CAS No. 166095-21-2. Molecular formula: C22H21ClN4O2. Mole weight: 408.88. | |
BMS-192364 Quick inquiry Where to buy Suppliers range | BMS-192364 is a prominent and discriminating inhibitor, finding profound application in the research of cancer. Specifically designed for efficacious cancer research, this remarkable compound effectively obstructs kinases that play a crucial role in the propagation and sustenance of malignant cells. Synonyms: 2-(5-chloro-2-hydroxyphenyl)-5-[4-(trifluoromethyl)phenyl]-1H-1,2,4-triazol-3-one; BMS-192364; BMS 192364; BMS192364; UNII-1NC8D8P7QF. Grades: >98%. CAS No. 202822-21-7. Molecular formula: C15H9ClF3N3O2. Mole weight: 355.7. | |
BMS-192548 Quick inquiry Where to buy Suppliers range | BMS-192548 is a neuropeptide Y (NPY) receptor binding inhibitor produced by Aspergillus niger WB2346. It also has weak cytotoxicity, with an IC50 of 240 μmol/L for murine tumor cells M-109. Synonyms: TAN-1612. CAS No. 156368-93-3. Molecular formula: C21H18O9. Mole weight: 414.36. | |
BMS-193884 Quick inquiry Where to buy Suppliers range | BMS-193884, an oxazol derivative, has been found to be an endothelin A receptor antagonist and was once studied in the treatmen of heart failure. Uses: Endothelin receptor antagonists. Synonyms: BMS-193884; BMS 193884; BMS193884; 7ON53PV45J; SCHEMBL4204130; BDBM50091105; N-(3,4-dimethyl-1,2-oxazol-5-yl)-2-[4-(1,3-oxazol-2-yl)phenyl]benzenesulfonamide. Grades: 98%. CAS No. 176960-47-7. Molecular formula: C20H17N3O4S. Mole weight: 395.43. | |
BMS 193885 Quick inquiry Where to buy Suppliers range | BMS 193885. Group: Biochemicals. Grades: Purified. CAS No. 679839-66-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
BMS-193885 Quick inquiry Where to buy Suppliers range | BMS-193885 is a potent and selective neuropeptide Y1 receptor antagonist with IC50=5.9nM, Ki=3.3 nM. BMS-193885 displays > 47, > 100, > 160, > 160 and > 160-fold selectivity over σ1, α1, Y2, Y4 and Y5 receptors respectively. Synonyms: dimethyl 4-[3-[3-[4-(3-methoxyphenyl)piperidin-1-yl]propylcarbamoylamino]phenyl]-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; BMS 193885; 679839-66-8BMS-193885; BMS193885; BMS 193885. Grades: >98%. CAS No. 186185-03-5. Molecular formula: C33H42N4O6. Mole weight: 590.71. | |
BMS-193885 salt Quick inquiry Where to buy Suppliers range | BMS-193885 is a potent and selective neuropeptide Y1 receptor antagonist with IC50=5.9nM, Ki=3.3 nM. BMS-193885 displays > 47, > 100, > 160, > 160 and > 160-fold selectivity over σ1, α1, Y2, Y4 and Y5 receptors respectively. Synonyms: BMS 193885; BMS193885; 1, 4-dihydro-4- [3- [ [ [ [3- [4- (3-methoxyphenyl) -1-piperidinyl] propyl] amino] carbonyl] amino] phenyl] -2, 6-dimethyl-3, 5-dimethyl ester-3,5-pyridinedicarboxylic acid. Grades: >98%. CAS No. 679839-66-8. Molecular formula: C36H48N4O9. Mole weight: 680.79. | |
BMS-194449 Quick inquiry Where to buy Suppliers range | BMS-194449 was found to be a β-adrenergic receptor agonist that was once studied in antihyperglycaemics as well as obesity therapy. Synonyms: BMS-194449; BMS 194449; BMS194449; UNII-93ZDV2P17I; CHEMBL320915; 93ZDV2P17I; SCHEMBL7042103; BDBM50106794; (R) -N- (5- (2- ( (bis (4- (difluoromethoxy) phenyl) methyl) amino) -1-hydroxyethyl) -2-hydroxyphenyl) methanesulfonamide. Grades: 98%. CAS No. 170686-12-1. Molecular formula: C24H24F4N2O6S. Mole weight: 544.52. | |
BMS-195270 Quick inquiry Where to buy Suppliers range | BMS-195270 is a robust and discriminating small molecule inhibitor, finding paramount application in the biomedical sector. Its remarkable efficacy against fibroblast growth factor receptor 4 (FGFR4) imparts exceptional potency, rendering it a formidable intervention modality for malignancies driven by FGFR4. Synonyms: 2-(5-chloro-2-hydroxyphenyl)-5-[2-(trifluoromethyl)phenyl]-1H-1,2,4-triazol-3-one; BMS-195270; BMS 195270; BMS195270; UNII-20UM0T170J; CHEMBL13637; SCHEMBL5754043; 20UM0T170J. Grades: >98%. CAS No. 202822-23-9. Molecular formula: C15H9ClF3N3O2. Mole weight: 355.7. | |
BMS 195614 Quick inquiry Where to buy Suppliers range | BMS 195614 is a neutral RARα selective antagonist (Ki = 2.5 nM) and exhibits no significant effect on nuclear receptor corepressor (NCoR) binding. BMS 195614 moderately decreases SMRT binding to RAR and agonist-induced coactivator (CoA) recruitment. Synonyms: 4-[[[5,6-Dihydro-5,5-dimethyl-8-(3-quinolinyl)-2-naphthalenyl]carbonyl]amino]benzoic acid; 4-({[5,5-Dimethyl-8-(3-quinolinyl)-5,6-dihydro-2-naphthalenyl]carbonyl}amino)benzoic acid; Benzoic acid, 4-[[[5,6-dihydro-5,5-dimethyl-8-(3-quinolinyl)-2-naphthalenyl]carbonyl]amino]-; BMS 614. Grades: ≥98% by HPLC. CAS No. 253310-42-8. Molecular formula: C29H24N2O3. Mole weight: 448.51. | |
BMS 195614 Quick inquiry Where to buy Suppliers range | BMS 195614. Group: Biochemicals. Grades: Purified. CAS No. 253310-42-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
BMS-196085 Quick inquiry Where to buy Suppliers range | BMS-196085, a sulfanilamide derivative, has been found to be a β-adrenergic receptor agonist that was once studied in obesity as well as yype 2 diabetes mellitus. Synonyms: BMS-196085; BMS 196085; BMS196085; CHEMBL322862; FM0D5L3W03; SCHEMBL7042488; BDBM50106829; UNII-FM0D5L3W03; N-[5-[(1R)-2-[[(1R)-1-[4-(difluoromethoxy)phenyl]-2-phenylethyl]amino]-1-hydroxyethyl]-2-hydroxyphenyl]methanesulfonamide. Grades: 98%. CAS No. 170686-10-9. Molecular formula: C24H26F2N2O5S. Mole weight: 492.54. | |
BMS-202 Quick inquiry Where to buy Suppliers range | BMS-202 Inhibitor. Uses: Scientific use. Product Category: T3146. CAS No. 1675203-84-5. | |
BMS-202 Quick inquiry Where to buy Suppliers range | BMS-202, 98%. CAS No. 1675203-84-5. Ebrator Biochemicals provides scientists around the global scientific community with a wide range of high purity Life Science products & Fine Chemicals. | |
BMS-210285 Quick inquiry Where to buy Suppliers range | BMS-210285 is a synthetic bio-active chemical. Uses: A synthetic bio-active chemical. Synonyms: BMS-210285; BMS210285; BMS 210285; UNII-WS7S13Q9RH; CHEMBL60116; WS7S13Q9RH; SCHEMBL13550990; BDBM50073046. N-[5-[(1R)-2-[[(1R)-2-(3-chlorophenyl)-1-[4-(difluoromethoxy)phenyl]ethyl]amino]-1-hydroxyethyl]-2-hydroxyphenyl]methanesulfonamide. Grades: ≥98%. CAS No. 344607-69-8. Molecular formula: C24H25ClF2N2O5S. Mole weight: 526.98. | |
BMS-212 Quick inquiry Where to buy Suppliers range | BMS-212 is a potent and selective stimulator of glucokinase (GK) (EC50 = 35 nM) that is promisingly used as an antidiabetic. BMS-212 has a preference for GK in liver over GK in pancreas, of which the activation may lead to non-glucose-dependent insulin secretion. Half-life of BMS-212 is 4.2h, and oral bioavailability is 15%. Uses: Potential antidiabetic. Synonyms: BMS212; BMS 212. CAS No. 2173153-38-1. Molecular formula: C25H30N3O9PS2. Mole weight: 611.62. | |
BMS-212122 Quick inquiry Where to buy Suppliers range | BMS-212122 is a benzimidazole-based analogue of the potent MTP inhibitor BMS-201038. Synonyms: 9-[4-[2, 5-dimethyl-4-[[2-[4- (trifluoromethyl) phenyl]benzoyl]amino]benzimidazol-1-yl]butyl]-N- (2, 2, 2-trifluoroethyl) fluorene-9-carboxamide; BMS-212122; BMS212122; BMS 212122; UNII-0Z473OO6GB. Grades: >98%. CAS No. 194213-64-4. Molecular formula: C43H36F6N4O2. Mole weight: 754.76. | |
BMS 214428 Quick inquiry Where to buy Suppliers range | BMS 214428 has antineoplastic effect. Synonyms: dimethyl 4-[3-[[N-cyano-N'-[3- (4-phenylpiperidin-1-yl) propyl]carbamimidoyl]amino]phenyl]-2, 6-dimethyl-1, 4-dihydropyridine-3, 5-dicarboxylate; UNII-6774Z74TWN; 6774Z74TWN; BMS 214428; BMS-214428; BMS214428. Grades: >98%. CAS No. 216508-01-9. Molecular formula: C33H40N6O4. Mole weight: 584.71. | |
BMS-214662 Quick inquiry Where to buy Suppliers range | BMS-214662 is a Farnesyltransferase inhibitor and a nonsedating benzodiazepine derivative with potential antineoplastic activity. BMS-214662 inhibits the enzyme farnesyltransferase and the post-translational farnesylation of number of proteins involved in signal transduction, which may result in the inhibition of Ras function and apoptosis in susceptible tumor cells. Synonyms: BMS 214662; BMS214662; ARQ-171; ARQ 171; ARQ171; (R)-1-((1H-imidazol-5-yl)methyl)-3-benzyl-4-(thiophen-2-ylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-7-carbonitrile. Grades: 98%. CAS No. 195987-41-8. Molecular formula: C25H23N5O2S2. Mole weight: 489.61. | |
BMS-214662 hydrochloride Quick inquiry Where to buy Suppliers range | BMS-214662, a nonsedating benzodiazepine derivative, inhibits the enzyme farnesyltransferase and the post-translational farnesylation of number of proteins involved in signal transduction. Treatment with BMS-214662 may result in the inhibition of Ras function and apoptosis in susceptible tumor cells. BMS-214662 may be a useful drug for treating B-CLL and, in particular, an alternative for the therapy of purine analog-resistant or relapsed B-CLL. Synonyms: (3R)-3-benzyl-1-(1H-imidazol-5-ylmethyl)-4-thiophen-2-ylsulfonyl-3,5-dihydro-2H-1,4-benzodiazepine-7-carbonitrile; 7-cyano-2,3,4,5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-3-(phenylmethyl)-4-(2-thienylsulfonyl)-1H-1,4-benzodiazepine; ARQ171; ARQ 171; ARQ-171; BMS214662; BMS214662; BMS-214662. Grades: >98%. CAS No. 195981-08-9. Molecular formula: C25H24ClN5O2S2. Mole weight: 526.1. | |
BMS-214662 mesylate Quick inquiry Where to buy Suppliers range | BMS-214662 mesylate is a potent and selective inhibitor of farnesyltransferase that induces mitochondrial apoptosis in chronic myeloid leukemia stem/progenitor cells, including CD34+38- cells, through activation of protein kinase C&beta. Uses: A potent and selective inhibitor of farnesyltransferase. Synonyms: BMS-214662 mesylate; BMS 214662 mesylate; BMS214662 mesylate; (R)-2,3,4,5-Tetrahydro-1-(1H-imidazol-4-ylmethyl)-3-(phenylmethyl)-4-(2-thienylsulfonyl)-1H-1,4-Benzodiazepine-7-carbonitrile monohydrochloride, (R)-7-Cyano-2,3,4,5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-3-(phenylmethyl)-4-(2-thienylsulfonyl)-1H-1,4-benzodiazepine mesylate. Grades: ≥98%. CAS No. 474010-58-7. Molecular formula: C25H25N5O6S3. Mole weight: 585.72. | |
BMS-229724 Quick inquiry Where to buy Suppliers range | BMS-229724 is a selective tight-binding inhibitor of cytosolic phospholipase A2 (cPLA2) in that it did not inhibit secreted phospholipase A2 in vitro, nor phospholipase C and phospholipase D in cells. BMS-22972 acts at the lipid/water interface and possesses anti-inflammatory activity in skin inflammation models. Synonyms: 4-[4-[2-[2-[bis (4-chlorophenyl) methoxy]ethylsulfonyl]ethoxy]phenyl]-1, 1, 1-trifluorobutan-2-one; 4- (4- (2- (2- (bis (4-chlorophenyl) methoxy) ethylsulfonyl) ethoxy) phenyl) -1, 1, 1-trifluoro-2-butanone; BMS-229724; BMS 229724; BMS229724; 42AD6D8ECA; SCHEMBL3304414; LS-46643; UNII-42AD6D8ECA. Grades: >98%. CAS No. 221914-85-8. Molecular formula: C27H25Cl2F3O5S. Mole weight: 589.45. | |
BMS-243117 Quick inquiry Where to buy Suppliers range | BMS-243117 is a potent and selective Lck inhibitor with good cellular activity against T-cell proliferation. BMS-24311 has potential to treat diseases such as rheumatoid arthritis and asthma. Synonyms: BMS-243117; BMS 243117; BMS243117; UNII-MBE6KWV0QI; CHEMBL67237; MBE6KWV0QI; SCHEMBL6058200. 2-(tert-butylcarbamoylamino)-N-(2-chloro-6-methylphenyl)-1,3-benzothiazole-6-carboxamide; BMS-243117; UNII-MBE6KWV0QI. Grades: >98%. CAS No. 225521-80-2. Molecular formula: C20H21ClN4O2S. Mole weight: 416.92. | |
BMS-247243 Quick inquiry Where to buy Suppliers range | BMS-247243 is a novel β-Lactamase inhibitor which is a family of enzymes involved in bacterial resistance to beta-lactam antibiotics. Uses: Beta-lactamase-inhibitor. Synonyms: BMS-247243; BMS 247243; BMS247243; UNII-KG8365V22L. (6R,7R)-7-[[2-[4-[(E)-3-(carboxylatomethylamino)-3-oxoprop-1-enyl]-2,5-dichlorophenyl]sulfanylacetyl]amino]-3-[[2,6-dimethyl-1-[3-(4-methylmorpholin-4-ium-4-yl)propyl]pyridin-1-ium-4-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate. Grades: ≥98%. CAS No. 307316-55-8. Molecular formula: C36H41Cl2N5O8S3. Mole weight: 838.83. | |
BMS-248360 Quick inquiry Where to buy Suppliers range | BMS-248360 is a first orally active generation dual action receptor antagonist. BMS-248360 antagonized both Ang II AT1 and endothelin ETA receptors (AT1 IC50=8.5, ETA IC50=8.9 nM). Synonyms: 2-[4-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-2-[(3,3-dimethyl-2-oxopyrrolidin-1-yl)methyl]phenyl]-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzenesulfonamide; BMS-248360; BMS 248360; BMS248360; UNII-EEP77N970Y; CHEMBL11706; EEP77N970Y; SCHEMBL4764273; BDBM50117910. Grades: >98%. CAS No. 254737-87-6. Molecular formula: C36H45N5O5S. Mole weight: 659.84. | |
BMS 262084 Quick inquiry Where to buy Suppliers range | BMS 262084 is a potent and selective azetidinone-based beta-lactam tryptase inhibitor. Synonyms: (2S,3R)-1-[4-(tert-butylcarbamoyl)piperazine-1-carbonyl]-3-[3-(diaminomethylideneamino)propyl]-4-oxoazetidine-2-carboxylic acid; BMS-262084; BMS 262084; BMS262084; CHEMBL71037; UNII-I0IR71971G; I0IR71971G; BDBM50120368; DNC004491. Grades: >98%. CAS No. 253174-92-4. Molecular formula: C18H31N7O5. Mole weight: 425.48. | |
BMS-265246 Quick inquiry Where to buy Suppliers range | BMS-265246 is a potent and selective pyra-zolopyridine based inhibitor of cdk2/cyclinE, cdk1/cyclinB and cdk4/ cyclinD. Group: Biochemicals. Alternative Names: (4-Butoxy-1H-pyrazolo[3, 4-b]pyridin-5-yl) (2, 6-difluoro-4-methylphenyl) methanone. Grades: Highly Purified. CAS No. 582315-72-8. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
BMS-265246 Quick inquiry Where to buy Suppliers range | BMS-265246 is a potent and selective CDK1/2 inhibitor with IC50 of 6 nM/9 nM. It is 25-fold more selective for CDK1/2 than CDK4. Synonyms: BMS265246; BMS-265246; BMS 265246. Grades: >98%. CAS No. 582315-72-8. Molecular formula: C18H17F2N3O2. Mole weight: 345.34. | |
BMS 270394 Quick inquiry Where to buy Suppliers range | BMS 270394 is a nuclear retinoic acid receptor (RAR-γ) agonist. Synonyms: BMS270394; BMS-270394 ; BMS 270394; BMS 189961; BMS189961; BMS-189961; (R)-3-fluoro-4-(2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)acetamido)benzoic acid; 3-fluoro-4-[[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)acetyl]amino]benzoic acid. Grades: 99%. CAS No. 262433-54-5. Molecular formula: C23H26FNO4. Mole weight: 399.46. | |
BMS-275183 Quick inquiry Where to buy Suppliers range | BMS-275183 is an oral C-4 methyl carbonate analogue of paclitaxel that has the same mechanism of action, stabilization of tubulin polymerization. BMS-275183 given p.o. was active in a human, hormone-dependent, prostate tumor model, CWR-22, and just as effective as anti-androgen chemotherapy. BMS-275185 is lack of evidence of clinical benefit with the occurrence of two fatal events of neutropenic sepsis. Synonyms: BMS 275183; BMS275183. CAS No. 355113-98-3. Molecular formula: C43H59NO16. Mole weight: 845.94. | |
BMS-279700 Quick inquiry Where to buy Suppliers range | BMS-279700, belonging to a family of novel anilino 5-azaimidazoquinoxaline analogues, is an orally active lead candidate that blocks the production of proinflammatory cytokines (IL-2 and TNFalpha) in vivo. Synonyms: (S)-N-(2-chloro-6-methylphenyl)-2-(3-methylpiperazin-1-yl)imidazo[1,5-a]pyrido[3,2-e]pyrazin-6-amine; BMS279700; BMS 279700; BMS-279700. Grades: >98%. CAS No. 240814-54-4. Molecular formula: C21H22ClN7. Mole weight: 407.899. | |
BMS-281384 bis-HCl Quick inquiry Where to buy Suppliers range | ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 261769-44-2 (free base). Pack Sizes: 5MG, 25MG. Mole weight: 523.84. Catalog: ALP261769442. Assay: ≥98% (HPLC). | |
BMS-284640 Quick inquiry Where to buy Suppliers range | BMS-284640 is a Na(+)/H(+) exchanger (NHE) inhibitor developed for the treatment of cardiovascular therapies. Synonyms: BMS 284640; BMS284640; N-[(1R,3R)-3-(2,3-Dihydro-benzofuran-4-yl)-2,2-dimethyl-cyclopropanecarbonyl]-guanidine. Grades: >98%. CAS No. 230640-88-7. Molecular formula: C15H19N3O2. Mole weight: 273.33. | |
BMS 299897 Quick inquiry Where to buy Suppliers range | BMS 299897, under the IUPAC name 4-[2-[(1R)-1-(N-(4-chlorophenyl)sulfonyl-2,5-difluoroanilino)ethyl]-5-fluorophenyl]butanoic acid, synthesized by the radiosynthesis group at Bristol-Myers Squibb, is a β-secretase inhibitor that has the potential for treatment of Alzheimer's diseases (IC50 = 12 nM; gamma-secretase express: EC50 = 7 nM (CHO cells)). BMS 299897 blocks the formation of Aβ40 (IC50 = 7.9 nM) and Aβ42 (IC50 = 7.9 nM) in the brain, and reduces Aβ in the brain, plasma and cerebrospinal fluid in vivo. Synonyms: 4-[2-[(1R)-1-(N-(4-chlorophenyl)sulfonyl-2,5-difluoroanilino)ethyl]-5-fluorophenyl]butanoic acid; 4-(2-((1R)-1-(((4-chlorophenyl)sulfonyl)-2,5-difluoroanilino)ethyl)-5-fluorophenyl)butanoic acid; BMS299897; BMS 299897; BMS-299897; 290315-45-6; 2-[(1R)-1-[[(4-Chlorophenyl)sulfonyl](2,5-difluorophenyl)amino]ethyl]-5-fluoro-benzenebutanoic acid; C24H21ClF3NO4S; CHEMBL247471; SCHEMBL6394108; DTXSID50460039; 3496AH; ZINC28883606; AKOS024457319; CCG-222540; CS-1339; NCGC00346875-01; HY-50883; KB-75603; DB-017854; W-5550; BRD-K02950022-001-01-1; 2-[(1R)-1-[[(4-chlorophenyl)sulfonyl](2,5-difluorophenyl)amino]ethyl]-5-fluoroBenzenebutanoic acid; BMS 299897|2-[(1R)-1-[[(4-Chlorophenyl)sulfonyl](2,5-difluorophenyl)amino]ethyl-5-fluorobenzenebutanoic acid. CAS No. 290315-45-6. Molecular formula: C24H21ClF3NO4S. Mole weight: 511.94. | |
BMS 299897 Quick inquiry Where to buy Suppliers range | BMS 299897 is a known γ-secretase inhibitor that effectively reduces amyloid β-peptide (A β) in transgenic mice and guinea pigs. Studies have shown the possibility of using BMS 299897 in the treatments for Alzheimers patients. Group: Biochemicals. Alternative Names: 2-[ (1R) -1-[[ (4-Chlorophenyl) sulfonyl] (2, 5-difluorophenyl) amino]ethyl]-5-fluorobenzenebutanoic Acid. Grades: Highly Purified. CAS No. 290315-45-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
BMS 299897, gamma-Secretase Inhibitor XXIV (4-(2-((1R)-1-(((4-Chlorophenyl)sulfonyl)-2,5-difluoroanilino)ethyl)-5-fluorophenyl)butanoic Acid, BMS-299897, BMS 299897) Quick inquiry Where to buy Suppliers range | An orally bioavailable sulfonamide compound that acts as a potent, reversible and allosteric y-secretase activity inhibitor with ~15-fold greater selectivity over Notch-1 proteolysis processing (IC50=7.1 and 105.9nM in HEK293-wtAPP) and preferentially inhibits PS1 (presenillin 1)-comprised y-secretase (EC50=8, 108, 286 and 29nM for PS1, Triple PS1-L172M,T281P, L282I, PS2 and Triple PS2-M178L, P287T, I288L), respectively). Shown to reduce the levels of Ab38, Ab40 and Ab42 in Tg2576 mice, Ab40 brain and plasma in APP-YAC mice (ED50=30 and 16mg/kg, p.o.) and Abtotal brain, CSF and plasma in guinea pigs (ED50=30mg/kg, i.p.). Group: Biochemicals. Grades: Highly Purified. CAS No. 290315-45-6. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
BMS-3 Quick inquiry Where to buy Suppliers range | BMS-3, a LIMK1 inhibitor, could be probably influence the migration and cycle progression of cells so that has patential value in studying its effect against cancer. Synonyms: N-(5-(1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl)thiazol-2-yl)cyclopropanecarboxamide; BMS3; BMS 3; Cyclopropanecarboxamide, N-[5-[1-(2,6-dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl]-2-thiazolyl]-; N-{5-[1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl]-1,3-thiazol-2-yl}cyclopropanecarboxamide. Grades: 95%. CAS No. 1338247-30-5. Molecular formula: C17H12Cl2F2N4OS. Mole weight: 429.27. | |
BMS 303141 Quick inquiry Where to buy Suppliers range | BMS 303141. Group: Biochemicals. Grades: Purified. CAS No. 943962-47-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
BMS303141 Quick inquiry Where to buy Suppliers range | BMS 303141 is a cell-permeable, 2-hydroxy-N-arylbenzenesulfonamide that inhibits ACL with an IC50 value of 0.13 μM. BMS 303141 has been reported to reduce weight gain and lower plasma cholesterol, triglycerides, and glucose in a mouse model of hyperlipidemia. Synonyms: BMS303141; BMS-303141; BMS 303141. CAS No. 943962-47-8. Molecular formula: C19H15Cl2NO4S. Mole weight: 424.30. | |
BMS 303141 (ATP Citrate Lyase Inhibitor, Orally Bioavailable, 3,5-Dichloro-2-hydroxy-N-(4-methoxy[1,1'-biphenyl]-3-yl)-benzenesulfonamide) Quick inquiry Where to buy Suppliers range | ATP citrate lyase (ACL) inhibitor (IC50 = 0.13um for human recombinant ACL); blocks lipid synthesis (IC50 = 8um in HepG2 cells). Displays no cytotoxicity up to a concentration of 50um. Lowers plasma glucose and triglycerides in a mouse model of hyperlipidemia. Orally bioavailable. Group: Biochemicals. Grades: Highly Purified. CAS No. 943962-47-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
BMS 309403 Quick inquiry Where to buy Suppliers range | BMS 309403. Group: Biochemicals. Grades: Purified. CAS No. 300657-03-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
BMS 309403 Quick inquiry Where to buy Suppliers range | BMS 309403 is a potent, selective and cell-permeable inhibitor of adipocyte fatty acid binding protein (FABP4) with a Ki of less than 2 nM, which exhibits Ki values of 250 nM for FABP3 and 350 nM for FABP5. BMS 309403 interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS 309403 is a biphenyl azole inhibitor against fatty acid binding protein 4 (FABP4) and regarded as a lead compound for effective treatment of obesity related cardio-metabolic diseases. Synonyms: BMS-309403; BMS309403; Adipocyte FABP Inhibitor; A-FABP Inhibitor; ALBP Inhibitor; aP2 Inhibitor; FABP4 Inhibitor; Fatty Acid Binding Protein 4 Inhibitor. Grades: ≥98%. CAS No. 300657-03-8. Molecular formula: C31H26N2O3. Mole weight: 474.55. | |
BMS-317180 Quick inquiry Where to buy Suppliers range | BMS-317180 is a potent, and orally effective growth hormone secretagogue (GHS) that shows an excellent safety profile in preclinical studies. Synonyms: BMS317180; BMS 317180; (S)-2-(5-(1-(2-amino-2-methylpropanamido)-2-(benzyloxy)ethyl)-1H-tetrazol-1-yl)ethyl (4-hydroxybutyl)carbamate. Grades: >98%. CAS No. 295337-71-2. Molecular formula: C26H30N5O2P. Mole weight: 463.54. | |
BMS-337197 Quick inquiry Where to buy Suppliers range | BMS-337197 is a a potent inhibitor of IMPDH with potential anticancer activity. Synonyms: BMS 337197; BMS337197; N-(2-(2-((3-methoxy-4-(oxazol-5-yl)phenyl)amino)oxazol-5-yl)phenyl)-N-methyl-2-morpholinoacetamide. Grades: >98%. CAS No. 267645-83-0. Molecular formula: C24H34N5OP. Mole weight: 489.53. | |
BMS-344577 Quick inquiry Where to buy Suppliers range | BMS-344577 is aroylguanidine-based lactam derivative, which is a potent FXa inhibitor (FXa IC(50)=4 nM, EC(2xPT)=7 microM). Uses: Aroylguanidine-based factor xa inhibitor. Synonyms: BMS-344577; BMS344577; BMS 344577; UNII-U259PQB19A; CHEMBL570867; U259PQB19A; BDBM35316; BDBM50328724; N5-[[[(3S)-Hexahydro-2-oxo-1-[2-oxo-2-(1-pyrrolidinyl)ethyl]-1H-azepin-3-yl]imino][(2-methyl-5-benzofuranyl)amino]methyl]-N2,N2-dimethyl-2,5-pyridinedicarboxamide;(S,E)-N2,N2-dimethyl-N5-(N'-(2-methylbenzofuran-5-yl)-N-(2-oxo-1-(2-oxo-2-(pyrrolidin-1-yl)ethyl)azepan-3-yl)carbamimidoyl)pyridine-2,5-dicarboxamide. Grades: ≥95%. CAS No. 288079-93-6. Molecular formula: C31H37N7O5. Mole weight: 587.67. | |
BMS 345541 Quick inquiry Where to buy Suppliers range | BMS 345541. Group: Biochemicals. Grades: Purified. CAS No. 547757-23-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
BMS-345541 Quick inquiry Where to buy Suppliers range | BMS-345541 is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM, respectively. Synonyms: BMS-345541 free base; BMS345541; UNII-26SU0NEF5F; BMS 345541; BMS-345541. Grades: >98%. CAS No. 445430-58-0. Molecular formula: C14H17N5. Mole weight: 255.32. | |
BMS-345541 Quick inquiry Where to buy Suppliers range | ≥98% (HPLC), powder. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 547757-23-3. Pack Sizes: 5MG, 25MG. Mole weight: 291.78. Catalog: AP547757233. Assay: ≥98% (HPLC). | |
BMS 345541 trifluoroacetate salt Quick inquiry Where to buy Suppliers range | BMS 345541 is a cell-permeable inhibitor of the IκB kinases IKKα with IC50s of 4 uM and IKKβ with IC50s of 0.3 μM, which binds at allosteric site of the enzyme and displays ~10-fold greater selectivity at IKK-2 over IKK-1. It exhibits no effect against a panel of 15 other kinases. BMS 345541 is used to explore novel roles for IKK phosphorylation and NF-κB signaling. Synonyms: IKK Inhibitor III. Grades: ≥98%. CAS No. 547757-23-3. Molecular formula: C14H17N5·2CF3COOH. Mole weight: 483.4. | |
BMS-347070 Quick inquiry Where to buy Suppliers range | BMS-347070 is a COX-2 inhibitor, initially developed for the treatment for Colorectal cancer. Synonyms: (3Z) -3-[ (4-bromophenyl) - (4-methylsulfonylphenyl) methylidene]oxolan-2-one; BMS-347070; BMS 347070; BMS347070; UNII-0CKM4H090C; 0CKM4H090C; SCHEMBL6882900; SCHEMBL6882905. Grades: >98%. CAS No. 197438-73-6. Molecular formula: C18H15BrO4S. Mole weight: 407.28. | |
BMS-351 Quick inquiry Where to buy Suppliers range | BMS-351 is a selective and nonsteroidal CYP17A1 lyase inhibitor with good selectivity over steroidogenic CYPs 21A2 and 11B1. BMS-351 has become a preclinical candidate to treat Castration-resistant prostate cancer (CRPC) and is likely to minimize the side effects of current therapies because of its exceptional selectivity. Uses: Castration-resistant prostate cancer. Synonyms: BMS-351; BMS 351; BMS351; 4-(4-methylpyridin-3-yl)-1-(2,2,2-trifluoroethyl)-1H-benzo[d]imidazole. Grades: 98%. CAS No. 1370001-71-0. Molecular formula: C15H12F3N3. Mole weight: 291.28. | |
BMS-354326 Quick inquiry Where to buy Suppliers range | BMS-354326 is a tryptase inhibitor with IC50 value of 1.8 nM. It has excellent selectivity against trypsin and most other related serine proteases. Synonyms: BMS-354326; BMS 354326; BMS354326; CHEMBL306448; BDBM50144532.(2S,3R)-4-oxo-1-((4-(1-oxo-6-phenylhexyl)-1-piperazinyl)carbonyl)-3-(2-(3-piperidinyl)ethyl)- 2-Azetidinecarboxylic acid. Grades: 98%. CAS No. 708258-16-6. Molecular formula: C28H40N4O5. Mole weight: 512.65. | |
BMS358233 Quick inquiry Where to buy Suppliers range | BMS358233 is a potent Lck inhibitor. It has excellent cellular activities against T-cell proliferation. Uses: Bms358233 has excellent cellular activities against t-cell proliferation. Synonyms: BMS-358233; BMS 358233; 6-Benzothiazolecarboxamide, N-(2-chloro-6-methylphenyl)-2-((6-methyl-2-((((2R)-tetrahydro-2-furanyl)methyl)amino)-4-pyrimidinyl)amino)-. Grades: 98%. CAS No. 601519-75-9. Molecular formula: C25H25ClN6O2S. Mole weight: 509.02. | |
BMS-36313 Quick inquiry Where to buy Suppliers range | BMS-363131 is very potent inhibitor of human tryptase with inhibitory activity against bovine trypsin. Uses: Tryptase inhibitor. Synonyms: BMS-363131; BMS 363131; BMS363131. (2S,3R)-3-[[(3R)-1-carbamimidoylpiperidin-3-yl]methyl]-4-oxo-1-[4-(6-phenylhexanoyl)piperazine-1-carbonyl]azetidine-2-carboxylic acid. Grades: ≥98%. CAS No. 384829-65-6. Molecular formula: C28H40N6O5. Mole weight: 540.66. | |
BMS-378806 Quick inquiry Where to buy Suppliers range | BMS-378806 selectively inhibits the binding of HIV-1 gp120 to the CD4 receptor with EC50 of 0.85-26.5 nM in virus. Synonyms: BMS-378806; BMS 378806; BMS378806; BMS-806; BMS806; Bms 806. Grades: >98%. CAS No. 357263-13-9. Molecular formula: C22H22N4O4. Mole weight: 406.43. | |
BMS-394136 Quick inquiry Where to buy Suppliers range | BMS-394136 is a synthetic bio-active chemical. Uses: A synthetic bio-active chemical. Synonyms: BMS-394136; BMS 394136; BMS394136;UNII-M694U7167K. [(7R)-7-(3,4-dichlorophenyl)-5-methyl-1,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl]-[(2S)-2-(4-fluorophenyl)pyrrolidin-1-yl]methanone. Grades: ≥98%. CAS No. 343246-73-1. Molecular formula: C24H21Cl2FN4O. Mole weight: 471.35. | |
BMS-419437 Quick inquiry Where to buy Suppliers range | BMS-419437 is a synthetic organic bio-active chemical. Uses: A synthetic organic bio-active chemical. Synonyms: BMS-419437; BMS419437; BMS 419437; UNII-09RR39UU4V; CHEBI:34550; AC1NQZWA; BMS-387032 analog 2. N-[5-[(5-tert-butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]-2-[4-[(1,3-dihydroxypropan-2-ylamino)methyl]phenyl]acetamide. Grades: ≥98%. CAS No. 333389-24-5. Molecular formula: C23H30N4O4S2. Mole weight: 490.64. | |
BMS 433771 Quick inquiry Where to buy Suppliers range | BMS 433771 is a potent inhibitor of RSV replication in vitro with an average EC of 20nM. Uses: Viral fusion protein inhibitor. Synonyms: BMS 433771; BMS433771; BMS-433771; BMS-433771 HCl hydrate; BMS-433771 HCl; BMS-433771 hydrochloride. 1-cyclopropyl-1,3-dihydro-3-((1-(3-hydroxypropyl)-1H-benzimidazol-2-yl)methyl)-2H-Imidazo(4,5-c)pyridin-2-one. Grades: ≥98%. CAS No. 380603-10-1. Molecular formula: C20H21N5O2. Mole weight: 363.41. | |
BMS-433771 bis-hydrochloride monohydrate Quick inquiry Where to buy Suppliers range | ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 543700-67-0. Pack Sizes: 5MG, 25MG. Mole weight: 468.38. Catalog: AP543700670. Assay: ≥98% (HPLC). | |
BMS-433796 Quick inquiry Where to buy Suppliers range | BMS-433796 is a γ-secretase inhibitor. Chronic dosing of BMS-433796 in Tg2576 mice suggested a narrow therapeutic window and Notch-mediated toxicity at higher doses. Uses: Gamma secretase inhibitors and modulators. Synonyms: BMS433796; BMS-433796; BMS 433796. (2S)-2-[[(2S)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]amino]-N-[(5S)-3-methyl-4-oxo-5H-2,3-benzodiazepin-5-yl]propanamide; BMS-433796; UNII-R1E8M783K2; 935525-13-6; CHEMBL247361; R1E8M783K2; ZINC28899741; (alphaS)-N-[(1S)-2-[[(5S)-4,5-Dihydro-3-methyl-4-oxo-3H-2,3-benzodiazepin-5-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluoro-alpha-hydroxybenzeneacetamide; (S)-2-((S)-2-(3,5-difluorophenyl)-2-hydroxyacetamido)-N-((S)-3-methyl-4-oxo-4,5-dihydro-3H-benzo[d][1,2]diazepin-5-yl)propanamide; Benzeneacetamide, N-((1S)-2-(((5S)-4,5-dihydro-3-methyl-4-oxo-3H-2,3-benzodiazepin-5-yl)amino)-1-methyl-2-oxoethyl)-3,5-difluoro-alpha-hydroxy-, (alphaS)-. CAS No. 935525-13-6. Molecular formula: C21H20F2N4O4. Mole weight: 430.15. | |
BMS 453 Quick inquiry Where to buy Suppliers range | BMS 453. Group: Biochemicals. Grades: Purified. CAS No. 166977-43-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
BMS 453 Quick inquiry Where to buy Suppliers range | BMS 453 is a synthetic retinoid that acts as an RARβ agonist in vivo, and also an RARα and RARγ antagonist in vitro. It inhibits the proliferation of breast cells by inducing active transforming growth factor β (TGFβ) and causes G1 arrest. Synonyms: BMS453; BMS 453; BMS-453; BMS 189453; BMS-189453; BMS189453. 4-[(1E)-2-(5,6-Dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-benzoic acid. Grades: ≥98% by HPLC. CAS No. 166977-43-1. Molecular formula: C27H24O2. Mole weight: 380.48. | |
BMS 470539 dihydrochloride Quick inquiry Where to buy Suppliers range | BMS 470539 dihydrochloride is a potent and selective melanocortin MC1 receptor agonist (IC50 = 120 nM) with anti-inflammatory activity. It also inhibits leukocyte trafficking. Synonyms: BMS 470539 dihydrochloride; BMS470539 dihydrochloride; BMS-470539 dihydrochloride; 1-[1-(3-Methyl-L-histidyl-O-methyl-D-tyrosyl)-4-phenyl-4-piperidinyl]-1-butanone dihydrochloride. Grades: ≥98% by HPLC. Molecular formula: C32H41N5O4.2HCl. Mole weight: 632.62. | |
BMS 470539 dihydrochloride Quick inquiry Where to buy Suppliers range | BMS 470539 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 457893-92-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
BMS480404 Quick inquiry Where to buy Suppliers range | BMS480404 is a potent small molecule inhibitor. It bounds to human keratinocyte fatty acid-binding protein. Synonyms: BMS-480404; BMS 480404; (S)-2-(2,3-bis(2-chlorobenzyloxy)phenyl)-2-hydroxyacetic acid. Grades: 98%. CAS No. 533889-36-0. Molecular formula: C22H18Cl2O5. Mole weight: 433.28. | |
BMS-488043 Quick inquiry Where to buy Suppliers range | BMS-488043 is a small-molecule HIV fusion inhibitor. Uses: Hiv fusion inhibitor. Synonyms: BMS-488043; BMS488043; BMS 488043; UNII-MKS21EJ435; CHEMBL238103; BMS 043; 1-(4-benzoylpiperazin-1-yl)-2-(4,7-dimethoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione. Grades: ≥98%. CAS No. 452296-83-2. Molecular formula: C22H22N4O5. Mole weight: 422.44. |