American Chemical Suppliers
A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
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Product | Description | |
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b-L-Xylose-1-phosphate Quick inquiry Where to buy Suppliers range | b-L-Xylose-1-phosphate is an indispensable molecule utilized within the biomedical field, demonstrating to hold promise in the realm of pharmaceutical development, particularly in the realm of researchs targeting the rectification of aberrations pertinent to xylose metabolism. | |
BLZ945 Quick inquiry Where to buy Suppliers range | BLZ945 is an orally active, potent and selective CSF-1R inhibitor, which inhibits CSF-1R activity with an IC50 of 1nM and is more than 1000-fold selective against its closest receptor tyrosine kinase homologs c-KIT and Platelet-derived Growth Factor Receptor beta (PDGFRb). Synonyms: sotuletinib; BLZ 945; BLZ-945. Grades: >98%. CAS No. 953769-46-5. Molecular formula: C20H22N4O3S. Mole weight: 398.48. | |
BM152054 Quick inquiry Where to buy Suppliers range | BM152054, a thiazolidinedione, revealed to be potent PPARg-activators in transient transfection assays in vitro. Synonyms: BM152054; BM 152054; BM-152054; 5-[[4-[2-(5-methyl-2-thiophen-2-yl-1,3-oxazol-4-yl)ethoxy]-1-benzothiophen-7-yl]methyl]-1,3-thiazolidine-2,4-dione; BM 15.2054; BM-15.2054; BM15.2054. CAS No. 213411-84-8. Molecular formula: C22H18N2O4S3. Mole weight: 470.58. | |
Bm 15.766 Quick inquiry Where to buy Suppliers range | Bm 15.766. Group: Heterocyclic Organic Compound. Alternative Names: BM 15.766;Benzoic acid, 4-[2-[4-[3-(4-chlorophenyl)-2-propenyl]-1-piperazinyl]ethyl]-, sulfate (1:1) (9CI);4-(2-(4-(3-(4-chlorophenyl)allyl)piperazin-1-yl)ethyl)benzoic acid sulfate. CAS No. 86621-94-5. Molecular formula: C22H25ClN2O2.H2O4S. Mole weight: 482.982. Symbol: GHS07. Melting Point: >300°C. Safty Description: 26-36. Hazard statements: Xi. Supplemental Hazard Statements: H315-H319-H335. | |
BM-212 Quick inquiry Where to buy Suppliers range | BM-212, a piperazine derivative, has been found to be effective in restraining the mycobacteria and exhibit intracellular bactericidal activity at some extent. Uses: Anti-bacterial agents. Synonyms: BM-212; BM 212; BM212. UNII-U9HSU4GZWL; BM212; 1-[[1,5-bis(4-chlorophenyl)-2-methylpyrrol-3-yl]methyl]-4-methylpiperazine; 1-{[1,5-Bis(4-chlorophenyl)-2-methylpyrrol-3-yl]methyl}-4-methylpiperazine; U9HSU4GZWL. Grades: 98%. CAS No. 146204-42-4. Molecular formula: C23H25Cl2N3. Mole weight: 414.37. | |
BM-2419-1 Quick inquiry Where to buy Suppliers range | BM2419-1 is a human topoisomerase I inhibitor produced by Paecilomyces sp. BM2419. It can selectively inhibit human topoisomerase with an IC50 of 0.3 ng/mL. Molecular formula: C18H10O8. Mole weight: 354.27. | |
BM-2419-2 Quick inquiry Where to buy Suppliers range | BM2419-2 is a human topoisomerase I inhibitor produced by Paecilomyces sp. BM2419. It can selectively inhibit human topoisomerase with an IC50 of 0.6 ng/mL. Molecular formula: C19H12O7. Mole weight: 352.29. | |
BM 567 Quick inquiry Where to buy Suppliers range | Thromboxane A2 (TXA2) is a potent thrombogenic and vasoconstrictor eicosanoid. It has been reported as a causal factor in the onset of stroke and myocardial infarction. BM 567 is a dual acting antithrombogenic agent, which is acting as an inhibitor of thromboxane A2 (TXA2) synthase and an antagonist of the TP receptor. It also antagonizes the vascular smooth muscle TP receptor with an IC50 value of 1.1 nM. Synonyms: BM567; BM-567. Grades: ≥98%. CAS No. 284464-77-3. Molecular formula: C18H28N4O5S. Mole weight: 412.5. | |
b-Maleimidopropionic acid hydrazide 99+% Quick inquiry Where to buy Suppliers range | b-Maleimidopropionic acid hydrazide 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
b-Maltosyl azide Quick inquiry Where to buy Suppliers range | b-Maltosyl azide is a useful compound in the biomedical industry commonly used as a reactive probe in click chemistry reactions for the labeling of biomolecules and bioconjugation studies. This azide derivative can facilitate specific and efficient modifications of various drugs, peptides and nucleic acids. Synonyms: 4-O-a-D-Glucopyranosyl-b-D-glucopyranosyl azide. CAS No. 51970-30-0. Molecular formula: C12H21N3O10. Mole weight: 367.3. | |
b-Mangostin Quick inquiry Where to buy Suppliers range | b-Mangostin. Group: Biochemicals. Grades: Highly Purified. CAS No. 20931-37-7. Pack Sizes: 100mg. Molecular Formula: C25H28O6. US Biological Life Sciences. | Worldwide |
BMAP-18 Quick inquiry Where to buy Suppliers range | BMAP-18 is a truncated form of the antimicrobial peptide BMAP-271. Bovine myeloid antimicrobial peptide-27(BMAP-27) belongs to the Cathelicidin family of peptides which displays rapid bactericidal activity against Staphylococcus aureus, Streptococcus uberis, and Escherichia coli. BMAP-27 is cytotoxic to human erythrocytes and neutrophils, although at higher than microbicidal concentrations1-3. BMAP-18 displays much higher cell selectivity as compared to parental BMAP-27 because of their decreased hemolytic activity and retained antimicrobial activity. Uses: Antimicrobial Peptides. Product ID: AF3341. | |
BMAP-27 Quick inquiry Where to buy Suppliers range | Bovine myeloid antimicrobial peptide-27(BMAP-27) belongs to the cathelicidin family of peptides which displays rapid bactericidal activity against Staphylococcus aureus, Streptococcus uberis, and Escherichia coli1. Cathelicidins belong to the large group of cationic peptides with amphipathic properties and have critical role in mammalian innate immune system. BMAP-27 is cytotoxic to human erythrocytes and neutrophils, although at higher than microbicidal concentrations1-2. It has a potential for the treatment of bacterial infections in individuals with cystic fibrosis-associated lung infections. Uses: Antimicrobial Peptides. Product ID: AF3342. | |
BMEDA Quick inquiry Where to buy Suppliers range | BMEDA, 93798-62-0, N,N-Bis(2-mercaptoethyl)-N'',N''-diethylethylenediamine, 1J7PW297VP, n,n-bis(2-mercaptoethyl)-n',n'-diethylethylenediamine, Ethanethiol, 2,2'-((2-(diethylamino)ethyl)imino)bis-, 2-[2-(diethylamino)ethyl-(2-sulfanylethyl)amino]ethanethiol, N,N-Bis(2-mercaptoethyl)-N',N'-diethylenediamine, 2,2'-((2-(Diethylamino)ethyl)azanediyl)diethanethiol, UNII-1J7PW297VP, SCHEMBL1654597, 2,2'-[2-(Diethylamino)ethyl]iminobis(ethanethiol), 2,2'-((2-(DIETHYLAMINO)ETHYL)IMINO)BIS(ETHANETHIOL). | |
B melanoma antigen 1 (2-10) Quick inquiry Where to buy Suppliers range | B melanoma antigen 1. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-418. | |
b-Melanotropin(human)(9ci) Quick inquiry Where to buy Suppliers range | b-Melanotropin(human)(9ci). Group: Heterocyclic Organic Compound. Alternative Names: β-Melanocyte stimulating hormone human; |A-MSH human. Grades: 96%. CAS No. 17908-57-5. Product ID: ACM17908575. Molecular formula: C118H174N34O35S. Mole weight: 2660.94. IUPAC Name: β-Melanocyte Stimulating Hormone human. | |
BMeS-p-A Quick inquiry Where to buy Suppliers range | BMeS-p-A. Group: Other Materials. CAS No. 1678513-97-7. IUPAC Name: 2,5-bis(methylsulfonyl)benzene-1,4-diamine. Molecular Weight: 264.3g/mol. Molecular Formula: C8H12N2O4S2. SMILES: CS (=O) (=O)C1=CC (=C (C=C1N)S (=O) (=O)C)N. InChI: InChI=1S/C8H12N2O4S2/c1-15(11,12)7-3-6(10)8(4-5(7)9)16(2,13)14/h3-4H,9-10H2,1-2H3. InChIKey: PBKAXANOUZYEDU-UHFFFAOYSA-N. | |
b-Methylcrotonyl coenzyme A lithium salt Quick inquiry Where to buy Suppliers range | b-Methylcrotonyl coenzyme A lithium salt, a crucial compound in the biomedicine realm, boasts paramount importance. Its pivotal function lies in the treatment of diverse ailments, notably beta-ketothiolase deficiencya scarcely encountered metabolic anomaly. Operating as a coenzyme, this product facilitates the degradation of fatty acids, thereby ensuring optimal energy metabolism within the organism. Synonyms: (c5:1)Coenzyme a lithium salt; trans-3-Methyl-2-butenoyl Coenzyme A; lithium [ (2R, 3S, 4R, 5R) -5- (6-aminopurin-9-yl) -4-hydroxy-2- [ [hydroxy- [hydroxy- [3-hydroxy-2, 2-dimethyl-4- [ [3- [2- (3-methylbut-2-enoylsulfanyl) ethylamino] -3-oxopropyl] amino] -4-oxobutoxy] phosphoryl] oxyphosphoryl] oxymethyl] oxolan-3-yl] hydrogen phosphate. Grades: ≥ 95%. CAS No. 108347-83-7. Molecular formula: C26H41LiN7O17P3S. Mole weight: 855.57. | |
b-Methyldigoxin Quick inquiry Where to buy Suppliers range | Cardiotonic. Obtained by the O-methylation of Digoxin. Group: Biochemicals. Alternative Names: (3 β,5 β,12 β)-3-[(O-2,6-Dideoxy-4-O-methyl- β-D-ribo-hexopyranosyl-(14)-O-2,6-dideoxy- β-D-ribo-hexopyranosyl-(14)-2,6-dideoxy- β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxycard-20(22)-enolide; 4-Methyldigoxin; 4-O-Methyldigoxin; Lanirapid; Lanitop; Medigoxin; Methyldigoxin; Metildigoxin. Grades: Highly Purified. CAS No. 30685-43-9. Pack Sizes: 1mg, 2.5mg, 5mg, 10mg. Molecular Formula: C42H66O14. US Biological Life Sciences. | Worldwide |
BMf-BH3 Quick inquiry Where to buy Suppliers range | BMf-BH3 belongs to the Bcl-2 apoptosis mediator family. BH3-only protein, Bmf is a key molecule for histone deacetylase (HDAC) inhibitors mediated enhancing effect on ionizing radiation-induced cell death. Uses: Peptide Inhibitors. Product ID: R1239. | |
BMH 21 Quick inquiry Where to buy Suppliers range | BMH 21. Group: Biochemicals. Grades: Purified. CAS No. 896705-16-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
BMH-21 Quick inquiry Where to buy Suppliers range | BMH-21 is a potent small molecule DNA intercalator. BMH-21 binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription. Uses: Enzyme inhibitors. Synonyms: BMH-21; BMH 21; BMH21. Grades: >98%. CAS No. 896705-16-1. Molecular formula: C21H22N4O2. Mole weight: 362.43. | |
BMI-1026 Quick inquiry Where to buy Suppliers range | BMI-1026 is an exceedingly potent and remarkably selective inhibitor utilized in the biomedical sector, specifically zeroes in on the intricate signalling pathway of interleukin-1 receptor-associated kinase 4 (IRAK-4). Synonyms: BMI 1026; BMI1026; 4-(2-Aminopyrimidin-4-yl)-6-(2-aminopyrimidin-4(3H)-ylidene)cyclohexa-2,4-dien-1-one. Grades: >98%. CAS No. 477726-77-5. Molecular formula: C34H60N3O7PS. Mole weight: 280.29. | |
Bmi1-Ring1A E3 Ligase Inhibitor, PRT4165 (2-(Pyridin-3-ylmethylene)-1H-indene-1,3(2H)-dione) Quick inquiry Where to buy Suppliers range | A cell-permeable indandione compound that inhibits the Bmi1-Ring1A E3 complex ubiquitin ligase activity both in cell-free assays (by 100% against self- and Top2alpha ubiquitination at 25 and 50uM, respectively) and in HeLa cells (by 100% against Bmi1 ubiquitination at 50uM). Shown to greatly potentiate Teniposide (VM26) cancer cytotoxicity (by 10-fold in A375 and A549 cultures at 5.5 and 33uM, respectively) by preventing Top2alpha degradation following VM26 treatment (100% inhibition at 50uM in HeLa cells). Group: Biochemicals. Grades: Highly Purified. CAS No. 31083-55-3. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
BmKb1 Quick inquiry Where to buy Suppliers range | BmKb1. Uses: Antimicrobial Peptides. Product ID: AF580. | |
BmKb1 Quick inquiry Where to buy Suppliers range | BmKb1 is produced by Mesobuthus martensii. BmKb1 has antibacterial activity against Gram-positive bacteria S.aureus, M.luteus, B.subtilis, and Gram-negative bacteria E.coli, and P.aeruginosa. Grades: >97% by HPLC. Molecular formula: C94H147N19O23. Mole weight: 1911.28. | |
BmKn1 Quick inquiry Where to buy Suppliers range | BmKn1 has antibacterial activity. BmKn1 was found in Mesobuthus martensii. | |
BmKn1 Quick inquiry Where to buy Suppliers range | BmKn1. Uses: Antimicrobial Peptides. Product ID: AF174. | |
BmKn2 Quick inquiry Where to buy Suppliers range | BmKn2. Uses: Antimicrobial Peptides. Product ID: AF173. | |
BmKn2 Quick inquiry Where to buy Suppliers range | BmKn2 was found in Mesobuthus martensii. BmKn2 has strong antibacterial activity against Gram-positive bacteria S.aureus, M.luteus, B.subtilis, and Gram-negative bacteria E.coli, P.aeruginosa and N.gonorrhoeae. BmKn2 also shows low activity against HIV-1 PV. | |
BML 111 Quick inquiry Where to buy Suppliers range | BML 111 is a FPR2 (lipoxin A4 receptor) agonist. It inhibits tumor-related angiogenesis and reduces tumor growth in hepatoma H22 cell bearing mice. BML 111 also protects against hemorrhagic shock-induced acute lung injury in rats and attenuates renal ischemia/reperfusion injury. Synonyms: BML-111; BML 111; BML111. (5S,6R)-Methyl 5,6,7-trihydroxyheptanoate; methyl (5S,6R)-5,6,7-trihydroxyheptanoate. CAS No. 78606-80-1. Molecular formula: C8H16O5. Mole weight: 192.21. | |
BML-190 Quick inquiry Where to buy Suppliers range | BML-190. Group: Biochemicals. Grades: Purified. CAS No. 2854-32-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
BML-210 Quick inquiry Where to buy Suppliers range | BML-210 is a Histone deacetylase (HDAC) inhibitor (IC50 = 87 μM), inducingchanges in gene expression profile. Uses: A histone deacetylase (hdac) inhibitor. Synonyms: BML-210; BML 210; BML210; CAY10433; CAY-10433; CAY 10433N1-(2-aminophenyl)-N8-phenyloctanediamide; N-(2-aminophenyl)-N'-phenyl-octanediamide. Grades: ≥98%. CAS No. 537034-17-6. Molecular formula: C20H25N3O2. Mole weight: 339.43. | |
BML-210 Quick inquiry Where to buy Suppliers range | BML 210. CAS No. 537034-17-6. | |
BML-210 Quick inquiry Where to buy Suppliers range | ≥98% (HPLC), powder. Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 537034-17-6. Pack Sizes: 5MG, 25MG. Mole weight: 339.43. Catalog: AP537034176. Assay: ≥98% (HPLC). | |
BML-210, HDAC Inhibitor (N1-(2-aminophenyl)-N8-. phenyloctanediamide) Quick inquiry Where to buy Suppliers range | A novel non-hydroxamic acid HDAC inhibitor. IC50=5-10uM (HeLa nuclear extract). Induces growth inhibition, proapoptotic and differentiation effects on human leukemia cell lines. Group: Biochemicals. Alternative Names: N1-(2-aminophenyl)-N8-phenyloctanediamide. Grades: Highly Purified. CAS No. 537034-17-6. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
BML-244 Quick inquiry Where to buy Suppliers range | BML-244 is a potent cathespin K inhibitor. Synonyms: BML 244; BML244; (1-formyl-pentyl)-carbamic acid tert-butyl ester; 2-[(tert-Butyloxycarbonyl)amino]hexanal. Grades: 98%. CAS No. 104062-70-6. Molecular formula: C11H21NO3. Mole weight: 215.29. | |
BML-258 HCl Quick inquiry Where to buy Suppliers range | Cas No. 1072443-89-0. | |
BML-275 Quick inquiry Where to buy Suppliers range | Cas No. 866405-64-3. | |
BML-277 Quick inquiry Where to buy Suppliers range | BML-277 is a selective APT-competitive inhibitor of the DNA damage response signaling enzyme CHK2 ( IC50 =15 nM). Uses: A selective apt-competitive inhibitor. Synonyms: BML-277; BML 277; BML277; Chk2 Inhibitor II;2-[4-(4-chlorophenoxy)phenyl]-3H-benzimidazole-5-carboxamide. Grades: ≥98%. CAS No. 516480-79-8. Molecular formula: C20H14ClN3O2. Mole weight: 363.80. | |
BML-278 Quick inquiry Where to buy Suppliers range | BML-278 is a selective Sirt1 activator (EC150 = 1μM) structurally based on a dihydropyridine scaffold. It has much weaker effects on Sirt2 and Sirt3. BML-278 is active in whole cells and arrests cell cycle at G1/S phase in U937 cells. It has much weaker effects on Sirt2 and Sirt3. BML-278 is active in whole cells and arrests cell cycle at G1/S phase in U937 cells. Synonyms: BML 278; BML278. Grades: ≥95%. CAS No. 120533-76-8. Molecular formula: C24H25NO4. Mole weight: 391.5. | |
BML-278, SIRT1 Inhibitor (N-Benzyl-3,5-dicarbethoxy-4-phenyl-1,4-dihydropyridine) Quick inquiry Where to buy Suppliers range | A structurally novel activator of SIRT1 (EC150=1uM). Displays selectivity over SIRT2 and 3 (EC150=25 and 50uM respectively). Cell permeable. Group: Biochemicals. Alternative Names: N-Benzyl-3,5-dicarbethoxy-4-phenyl-1,4-dihydropyridine. Grades: Highly Purified. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
BML-284 Quick inquiry Where to buy Suppliers range | BML-284 is potent, selective and cell-permeable Wnt signaling activator. It induces β-catenin and transcription factor (TCF)-dependent transcriptional activity in 293T cells in a dose dependent manner with an EC50 of 0.7 mM in vitro. Uses: Bml-284 may be a useful tool in the study of physiological processes that involve the wnt pathway. Synonyms: BML 284; 2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine; 4-N-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)pyrimidine-2,4-diamine. Grades: >98%. CAS No. 853220-52-7. Molecular formula: C19H18N4O3. Mole weight: 350.37. | |
BML-286 Quick inquiry Where to buy Suppliers range | A small molecule inhibitor of the PDZ domain of Dishevelled (Dvl): an essential protein in the Wnt signaling pathways. This compound reduced the levels of apoptosis in the hyaloid vessels of the eye and also suppressed the growth of prostate cancer PC-3 cells. It is a useful tool for studies dissecting the Wnt signaling pathways. Group: Biochemicals. Alternative Names: 2- [ [3- [ (2-phenylacetyl) amino] benzoyl] amino] benzoic Acid; 2- [ [3- [ (phenylacetyl) amino] benzoyl] amino] benzoic Acid. Grades: Highly Purified. CAS No. 294891-81-9. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
BML-287 Quick inquiry Where to buy Suppliers range | BML-287 is a selective inhibitor of secreted frizzled related protein-1 (sFRP-1). BML-287 is a useful tool for studying the Wnt signaling pathway. Group: Biochemicals. Alternative Names: N-[2- (3, 4-Dimethoxyphenyl) ethyl]-2-ethyl-5- (phenylsulfonyl) benzenesulfonamide. Grades: Highly Purified. CAS No. 915754-05-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
BML-288 Quick inquiry Where to buy Suppliers range | BML-288. Group: Biochemicals. Alternative Names: 6,7-Dihydro-5-methyl-6-oxo-N-1,3,4-thiadiazol-2-yl-5H-furo[2,3-f]indole-7-carboxamide. Grades: Highly Purified. CAS No. 851681-89-5. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C14H10N4O3S. US Biological Life Sciences. | Worldwide |
BMMCC Quick inquiry Where to buy Suppliers range | BMMCC. Pack Sizes: Milligram Quantities: 50 mg. Order Number: B111. | www.prochemonline.com |
BMN-673 8R,9S Quick inquiry Where to buy Suppliers range | BMN-673 is an orally bioavailable inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential antineoplastic activity. PARP inhibitor BMN-673 selectively binds to PARP and prevents PARP-mediated DNA repair of single strand DNA breaks via the base-excision repair pathway. This enhances the accumulation of DNA strand breaks, promotes genomic instability and eventually leads to apoptosis. PARP catalyzes post-translational ADP-ribosylation of nuclear proteins that signal and recruit other proteins to repair damaged DNA and is activated by single-strand DNA breaks. BMN-673 has been proven to be highly active in mouse models of human cancer and also appears to be more selectively cytotoxic with a longer half-life and better bioavailability as compared to other compounds in development. Synonyms: Talazoparib (8R,9S); (8R,9S)-BMN-673; BMN673 (8R,9S); BMN 673 (8R,9S). Grades: >98%. CAS No. 1207456-00-5. Molecular formula: C19H14F2N6O. Mole weight: 380.35. | |
BMP-22 Quick inquiry Where to buy Suppliers range | BMP-22 is an inhibitor of autotaxin with IC50 of 170 nM. It is selective for autotaxin over the phosphodiesterases NPP6 and NPP7 at 10 μM. BMP-22 inhibits autotaxin-mediated production of lysophosphatidic acid (LPA) from lysophosphatidylcholine (LPC) in vitro in a concentration-dependent manner. MP-22 can decrease the number of lung metastatic foci in a B16/F10 syngeneic mouse melanoma model of lung metastasis. Synonyms: 4-pentadecylbenzylphosphonic acid; BMP22; BMP 22. Grades: ≥95%. CAS No. 1306684-90-1. Molecular formula: C22H39O3P. Mole weight: 382.52. | |
BMP Inhibitor II, DMH1 (ALK2/3 Inhibitor, DMH1, Bone Morphogenetic Protein Inhibitor, DMH1, 4- (6- (4-Isopropoxyphenyl) pyrazolo[1, 5-a]pyrimidin-3-yl) quinoline) Quick inquiry Where to buy Suppliers range | A cell-permeable pyrrazolopyrimidine compound that inhibits against R/VEGFR2, ALK2/BMPR-I, AMPK kinase activity (IC50=25.1, 148, and 234.6nM, respectively), while exhibiting much reduced or little effect toward ALK5/TGFbR-I, ZAPK, Syk, PKCth, PKA, or JAK3. Shown to block both BMP pathway-dependent dorsoventral development (EC100=2.5uM) and VEGF signaling-dependent intersomitic vessel formation (EC50=5uM) in zebrafish embryo in vivo. Commonly used in combination with AMPK activators AICAR and/or Metformin for studying AMPK-dependent cellular events in vitro and physiological responses in animals in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 1206711-16-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
BMP Inhibitor III, LDN-212854 (Abl Inhibitor V, LDN212854, Bone Morphogenetic Protein Inhibitor III, PDGFR Tyrosine Kinase Inhibitor XXIV, RIP2 Inhibitor I, RIPK2 Inhibitor I, 5-(6-(4-(Piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline) Quick inquiry Where to buy Suppliers range | A cell-permeable pyrazolopyrimidinyl quinoline that is superior to Dorsomorphin and DMH1 as an ATP-site-targeting, ALK1/2 inhibitor (IC50 = 2.40 and 1.30nM, respectively; [ATP] = 6uM) with respect to both potency and selectivity over ALK3/4/5 (IC50 = 0.858, 2.133, and 9.276uM, respectively). Also a potent RIPK2 inhibitor (IC50 = 6nM) with reduced potency against ABL1/c-abl, PDGFR-beta, ALK3, and PDGFR-alpha (IC50 = 40, 68, 85.8, and 650nM, respectively) and little inhibitory activity toward a panel of more than 190 kinases. Effectively inhibits ALK2- and ALK3-mediated C2C12 osteogenic differentiation (IC50 = 10 and 40.5nM, respectively) in vitro and prevents constitutively active ALK2 Q207D mutant-induced heterotopic ossification in mice (6mg/kg/12h via i.p.) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C??H??N?. US Biological Life Sciences. | Worldwide |
BMPS Quick inquiry Where to buy Suppliers range | Cas No. 55750-62-4. | |
BmPyPhB Quick inquiry Where to buy Suppliers range | BmPyPhB. Group: Organic Light Emitting Diode (OLED). CAS No. 1030380-38-1. | |
BMS-002 Quick inquiry Where to buy Suppliers range | BMS-002 is a selective antogonist of lysophosphatidic acid (LPA) receptor-1 developed to treat diabetic nephropathy. In eNOS-/- db/db mouse model, BMS-002 significantly decreased the level of proteinuria. Uses: The potential treatment of diabetic nephropathy. Synonyms: BMS 002; BMS002. | |
BMS-180048 Quick inquiry Where to buy Suppliers range | BMS-180048, also know as Avitriptan Fumarate, has been found to be a5HT-1B/1D-receptor agonist that was once studied as an anti-migraine agent. Synonyms: Avitriptan Fumarate; BMS 180048; BMS-180048; BMS180048; UNII-2G25KE3954; 3-(3-(4--(5-methoxy-4-pyrimidinyl)-1-piperazinyl)propyl)-N-methyl-1H-indole-5-methanesulfonamide fumarate. Grades: 98%. CAS No. 171171-42-9. Molecular formula: C26H34N6O7S. Mole weight: 574.65. | |
BMS 180448 Quick inquiry Where to buy Suppliers range | BMS 180448 is a prototype mitochondrial ATP-sensitive K+ channel stimulant. The cardioprotective effects of BMS-180448 against I/R heart injury may result from direct activation of mitoK(ATP) channel in cardiomyocytes. In Sep 2003, Phase-II for Myocardial ischaemia in USA was discontinued. Uses: Myocardial ischaemia. Synonyms: BMS 180448; BMS-180448; BMS180448; trans-N-(4-chlorophenyl)-N'-cyano-N''-(6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl)- Guanidine. Grades: 98%. CAS No. 144264-47-1. Molecular formula: C20H18ClN5O2. Mole weight: 395.85. | |
BMS 180680 Quick inquiry Where to buy Suppliers range | BMS 180680 is antibacterial activity agent of new catechol-containing monobactam. It is a cell wall inhibitor. BMS-180680 is an active compound against many species of the family Enterobacteriaceae, with MICs at which 90% of the isolates were inhibited. In Oct 2002, Phase-II for Respiratory tract infections in USA was discontinued. Uses: Respiratory tract infections. Synonyms: BMS 180680; BMS180680; BMS-180680; SQ 84,100;(2R-(2alpha,3alpha(Z)))-3-((((1-(2-Amino-4-thiazolyl)-2-((2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino)-2-oxoethylidene)amino)oxy)methyl)-6,7-dihydroxy-2-quinoxalinecarboxylic acid. Grades: 98%. CAS No. 142654-34-0. Molecular formula: C19H17N7O10S2. Mole weight: 567.51. | |
BMS 181101 Quick inquiry Where to buy Suppliers range | BMS 181101, an indole derivative, has been found to be a 5-HT receptor agonist that could be probably effective against depression and also restrain serotonin reuptake at some extent. It has already been discontinued by Bristol-Myers Squibb. Synonyms: BMS 181101; BMS181101; BMS-181101; AC1L42ZR; SCHEMBL4356376; DTXSID40163380; 5-fluoro-3-[3-[4-(5-methoxypyrimidin-4-yl)piperazin-1-yl]propyl]-1H-indole Dihydrochloride. Grades: 98%. CAS No. 146479-45-0. Molecular formula: C20H26Cl2FN5O. Mole weight: 442.36. | |
BMS 181168 Quick inquiry Where to buy Suppliers range | This active molecular is an potential cognitive enhancer originated by Bristol-Myers Squibb. Mechanism of Action is not identified. Bmy 21502 is also a nootropic agent and it can protect rodents from ECS-induced amnesia in a step-down passive avoidance task. But clinical study for treatment of Alzheimer's disease was discontinued. Uses: Alzheimer's disease. Synonyms: Bmy 21502; Bmy21502; Bmy-21502; Bms-181168; Bms 181168; Bms181168. 1-((1-(2-(trifluoromethyl)pyrimidin-4-yl)piperidin-4-yl)methyl)pyrrolidin-2-one. Grades: 98%. CAS No. 123259-91-6. Molecular formula: C15H19F3N4O. Mole weight: 328.34. | |
BMS-181184 Quick inquiry Where to buy Suppliers range | BMS-181184 is an antifungal antibiotic produced by Actinomadura sp. AB1236 in a medium containing D-serine or D-cycloserine. It has activity against pathogenic fungi such as yeast, Candida albicans, Cryptococcus neoformans, Aspergillus fumigatus and Trichophyton. Synonyms: D-Serine, N-((5-((6-deoxy-3-O-beta-D-xylopyranosyl-beta-D-galactopyranosyl)oxy)-5,6,8,13-tetrahydro-1,6,9,14-tetrahydroxy-11-methoxy-3-methyl-8,13-dioxobenzo(a)naphthacen-2-yl)carbonyl)-, (5S-trans)-. CAS No. 139272-69-8. Molecular formula: C39H41NO20. Mole weight: 843.74. | |
BMS-181532 Quick inquiry Where to buy Suppliers range | BMS-181532 is an antifungal antibiotic produced by Actinomadura sp. AB1236 in a medium containing D-serine or D-cycloserine. It has activity against pathogenic fungi such as yeast, Candida albicans, Cryptococcus neoformans, Aspergillus fumigatus and Trichophyton. Synonyms: BMS 181532. CAS No. 146877-08-9. Molecular formula: C34H33NO16. Mole weight: 711.62. | |
BMS 182264 Quick inquiry Where to buy Suppliers range | BMS 182264 is a bio-active chemical, but few detailed information has been published yet. Synonyms: BMS 182264; BMS-182264; BMS182264; CHEMBL19169; N-Cyano-N'-(4-cyanophenyl)-N''-1,2,2-trimethylpropylguanidine. Grades: 98%. CAS No. 127749-54-6. Molecular formula: C15H19N5. Mole weight: 269.35. | |
BMS 182874 Quick inquiry Where to buy Suppliers range | BMS 182874 is an endothelin receptor antagonist used as an antihypertensive agent. Uses: Antihypertensive agents. Synonyms: 5-Ddins; BMS 182874; BMS-182874; BMS182874; CHEMBL267458; 5-(dimethylamino)-N-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide. CAS No. 153042-42-3. Molecular formula: C17H19N3O3S. Mole weight: 345.417. | |
BMS 182874 hydrochloride Quick inquiry Where to buy Suppliers range | BMS 182874 HYDROCHLORIDE, 1215703-04-0, 5-(Dimethylamino)-N-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide hydrochloride, 5-(dimethylamino)-N-(3,4-dimethylisoxazol-5-yl)naphthalene-1-sulfonamide hydrochloride, N-(3,4-Dimethyl-5-isoxazolyl)-5-(dimethylamino)-1-naphthalenesulfonamide hydrochloride, SCHEMBL117150, AKOS024456599, SR-01000597801, J-004534, SR-01000597801-1, 5-(dimethylamino)-N-(3,4-dimethyl-1,2-oxazol-5-yl)naphthalene-1-sulfonamide;hydrochloride, 5-(dimethylamino)-N-(3,4-dimethyl-1,2-oxazol-5-yl)naphthalene-1-sulfonamide;hydrochloride. | |
BMS 182874 Hydrochloride Quick inquiry Where to buy Suppliers range | This active molecular is a selective non-peptide Endothelin ETA receptor antagonist. It displays more than 1000-fold selectivity over ETB receptors (Ki of 48 nM for ETA receptors and >50 μM for ETB). BMS 182874 displays ET-1 inhibitory efficacy in vivo and vitro and it also inhibits ET-1-induced longitudinal muscle contraction in vitro. In 2006, BMS 182874 for coronary disorders and hypertension were discontinued in USA. Uses: Coronary disorders and hypertension. Synonyms: BMS 182874; BMS-182874; BMS182874; BMS 182874 HCl; BMS 182874 hydrochloride; 5-(dimethylamino)-N-(3,4-dimethylisoxazol-5-yl)naphthalene-1-sulfonamide hydrochloride. Grades: 98%. CAS No. 1215703-04-0. Molecular formula: C17H20ClN3O3S. Mole weight: 381.88. | |
BMS 183920 Quick inquiry Where to buy Suppliers range | BMS 183920, a quinoline derivative, has been found to be an angiotensin II receptor antagonist that could have potential usage in antihypertensive study. Uses: Angiotensin ii type 1 receptor blockers. Synonyms: BMS 183920; BMS-183920; BMS183920; CHEMBL305365; 2-Cyclopropyl-3-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)oxy)-4-quinolinecarboxylic acid; 4-Quinolinecarboxylicacid, 2-cyclopropyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]oxy]-. Grades: 98%. CAS No. 153072-33-4. Molecular formula: C26H19N5O3. Mole weight: 449.47. | |
BMS-186318 Quick inquiry Where to buy Suppliers range | BMS-186318 has been found to be a HIV protease inhibitor that was once studied against HIV by Bristol-Myers Squibb. Synonyms: BMS 186318; BMS-186318; BMS186318; 12-Oxa-2,6,10-triazatetradecanoic acid, 4,8-dihydroxy-13,13-dimethyl-3-((4-(2-(4-morpholinyl)-2-oxoethoxy)phenyl)methyl)-11-oxo-9-(phenylmethyl)-, 1,1-dimethylethyl ester, (3S,4R,8R,9S)-; BMS-186318 analog 19; 12-Oxa-2,6,10-triazat. Grades: 98%. CAS No. 161302-40-5. Molecular formula: C36H54N4O9. Mole weight: 686.85. | |
BMS-186511 Quick inquiry Where to buy Suppliers range | BMS-186511 is a Farnesyltransferase (FT) inhibitor with potential anticancer activity. Synonyms: BMS186511; BMS 186511; ((5S,8S,11S)-8,11-diisopropyl-5-(methoxycarbonyl)-7,10,13-trioxo-2-thia-6,9,12-triazapentadecan-15-yl)((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl)phosphinic acid. Grades: >98%. CAS No. 167467-53-0. Molecular formula: C26H27N5O5. Mole weight: 685.90. | |
BMS-187071 Quick inquiry Where to buy Suppliers range | BMS-187071 has been found to be a HIV protease inhibitor that was once studied against HIV by Bristol-Myers Squibb. Synonyms: BMS 187071; BMS187071; BMS187071; (3-((3-((2,3,3-Trimethyl-2(S)-2-hydroxy-1-oxobutyl)amino)-2-hydroxy-4-phenylbutyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)carbamic acid, 1,1-dimethylethyl ester; [3-[[3-[(2,3,3-Trimethyl-2(S)-2-hydroxy-1-oxobutyl)amino]-2-hydroxy-4. Grades: 98%. CAS No. 161302-39-2. Molecular formula: C32H49N3O6. Mole weight: 571.75. | |
BMS-187308 Quick inquiry Where to buy Suppliers range | BMS-187308, a sulfonamide derivative, has been found to be an endothelin-A (ETA) antagonist that was once studied about its activity against pressor effect in rats. Synonyms: BMS-187308; BMS 187308; BMS187308; UNII-7K0YU35900; CHEMBL106684; 7K0YU35900; SCHEMBL6767698; BDBM50068674; 2-[2-amino-4-(2-methylpropyl)phenyl]-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzenesulfonamide. Grades: 98%. CAS No. 153624-15-8. Molecular formula: C21H25N3O3S. Mole weight: 399.51. |