A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Brimonidine Tartrate is a highly selective α-adrenergic receptor agonist with EC50 of 0.45 nM for the α2A adrenoreceptor, and used to treat open-angle glaucoma or ocular hypertension. Synonyms: Brimonidine L-Tartrate; 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-6-quinoxalinamine L-Tartrate; 5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline; UK-14304-18; AGN-190342-LF. Grade: >98%. CAS No. 70359-46-5. Molecular formula: C15H16BrN5O6. Mole weight: 442.22.
Brimonidine Tartrate EP
Brimonidine Tartrate EP.
CA, FL & NJ
Brimonidine Tartrate Impurity 1
Brimonidine Tartrate Impurity 1 is a metabolite of Brimonidine. Synonyms: Brimonidine-2,3-dione; 5-Bromo-6-[(4,5-dihydro-1H-imidazol-2-yl)amino]-1,4-dihydro-2,3-quinoxalinedione. Grade: > 95%. CAS No. 182627-95-8. Molecular formula: C11H10BrN5O2. Mole weight: 324.14.
Brincidofovir
Brincidofovir (CMX001), the lipid-conjugated prodrug of Cidofovir (HY-17438), is an orally available, long-acting antiviral. Brincidofovir shows activity against a broad spectrum of DNA viruses including cytomegalovirus (CMV), adenovirus (ADV), varicella zoster virus, herpes simplex virus, polyomaviruses, papillomaviruses, poxviruses, and mixed double-stranded DNA virus infections. Brincidofovir, an oral antiviral in late stage development, has proven effective against orthopoxviruses in vitro and in vivo. [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CMX001; HDP-CDV. CAS No. 444805-28-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14532.
Brinzolamide
Brinzolamide. Group: Biochemicals. Alternative Names: (R)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide. Grades: Highly Purified. CAS No. 138890-62-7. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C12H21N3O5S3. US Biological Life Sciences.
Worldwide
Brinzolamide
Brinzolamide (AL-4862) is a selective carbonic anhydrase II inhibitor with an IC 50 value of 3.2 nM. Brinzolamide hydrochloride reduces intraocular pressure (IOP) by inhibiting ciliary CA-II and decreasing atrial fluid secretion. Brinzolamide can be used in glaucoma disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AL-4862. CAS No. 138890-62-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0588.
Brinzolamide
It has a role as an antiglaucoma drug and an EC 4.2.1.1 (carbonic anhydrase) inhibitor. Alternative Names: Brinzolamide. Azopt. AL-4862. CAS No. 138890-62-7. Product ID: API138890627. Molecular formula: C12H21N3O5S3. Mole weight: 383.5. EINECS: 620-511-8. SMILES: CCNC1CN(S(=O)(=O)C2=C1C=C(S2)S(=O)(=O)N)CCCOC. Appearance: Crystalline solid. Category: Ophthalmic APIs.
Brinzolamide
Brinzolamide is a potent carbonic anhydrase II inhibitor with IC50 of 3.19 nM. Uses: Carbonic anhydrase inhibitors. Synonyms: AL-4862; AL 4862; AL4862; Brinzolamide; trade names Azopt, Alcon Laboratories, Befardin, Fardi Medicals. Grade: >98%. CAS No. 138890-62-7. Molecular formula: C12H21N3O5S3. Mole weight: 383.51.
Brinzolamide-d5
Carbonic anhydrase inhibitor. Antiglaucoma agent. Group: Biochemicals. Alternative Names: (4R)-(Ethylamino-d5)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide; AL-4682-d5; Azopt-d5. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Brinzolamide-[d5]
Brinzolamide-[d5] is the labelled analogue of Brinzolamide. Brinzolamide is a carbonic anhydrase inhibitor used for the treatment of open-angle glaucoma and ocular hypertension. Synonyms: Brinzolamide D5; Brinzolamide-d5; (4R)-(Ethylamino-d5)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide; AL-4682-d5; Azopt-d5; (R)-4-((Ethyl-d5)amino)-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide. Grade: >95%. CAS No. 1217651-02-9. Molecular formula: C12H16D5N3O5S3. Mole weight: 388.54.
Brinzolamide hydrochloride
Brinzolamide is a potent carbonic anhydrase II inhibitor with IC50 of 3.19 nM. Synonyms: (4R)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-Dioxide Hydrochloride; AL-4682 Hydrochloride; Azopt Hydrochloride. CAS No. 150937-43-2. Molecular formula: C12H22ClN3O5S3. Mole weight: 419.97.
Brinzolamide Hydrochloride
Carbonic anhydrase inhibitor. Antiglaucoma agent. Group: Biochemicals. Alternative Names: (4R)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-Dioxide Hydrochloride; AL-4682 Hydrochloride; Azopt Hydrochloride. Grades: Highly Purified. CAS No. 150937-43-2. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Brinzolamide Impurity4
Brinzolamide Impurity4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(3-methoxypropyl)-4-oxo-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide. CAS No. 154127-41-0. Molecular formula: C10H14N2O6S3. Mole weight: 354.42. Catalog: APB154127410.
Brinzolamide Impurity5
Brinzolamide Impurity5. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-4-hydroxy-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide. CAS No. 154127-42-1. Molecular formula: C10H16N2O6S3. Mole weight: 356.44. Catalog: APB154127421.
Brinzolamide Impurity7
Brinzolamide Impurity7. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-4-(ethylamino)-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide. CAS No. 154127-19-2. Molecular formula: C12H21N3O5S3. Mole weight: 383.51. Catalog: APB154127192.
Brinzolamide maleate
A maleate salt of Brinzolamide. Brinzolamide is a potent carbonic anhydrase inhibitor used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Synonyms: Brinzolamide maleic acid adduct; 2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide, 4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-, 1,1-dioxide, (4R)-, (2Z)-2-butenedioate (1:1); (R)-4-(Ethylamino)-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide maleate. Grade: ≥95%. CAS No. 1448780-04-8. Molecular formula: C12H21N3O5S3.C4H4O4. Mole weight: 499.58.
Brinzolamide Related Compound A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Brinzolamide Related Compound B
Brinzolamide Related Compound B is Brinzolamide derivative. Synonyms: (4R)-4-Amino-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-Dioxide; AL 8520; N-Desethyl Brinzolamide. Grade: > 95%. CAS No. 404034-55-5. Molecular formula: C10H17N3O5S3. Mole weight: 355.46.
Brinzolamide Related Compound B
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Brinzolamide Related Compound C
Brinzolamide Related Compound C is an isomer of Brinzolamide. Synonyms: (S)-Brinzolamide; (S)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-Dioxide; AL 4862. Grade: > 95%. CAS No. 154127-19-2. Molecular formula: C12H21N3O5S3. Mole weight: 383.51.
Briquilimab
Briquilimab (JSP-191) is a non-toxic humanized monoclonal antibody targeting CD117 (c-Kit) to deplete hematopoietic stem cell (HSC). Briquilimab has safety to clear host marrow niche space to enable sufficient donor HSC engraftment and immune reconstitution as primary method of severe combined immunodeficiency (SCID) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: JSP-191. CAS No. 2574591-89-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99488.
Britannilactone
A bioassay-guided isolation of the chloroform fraction of the I. britannica using an in vitro melanogenesis inhibition assay led to the isolation of sesquiterpenes, 1-O-acetylbritannilactone (1), britannilactone (2) and neobritannilactone B (3). Compounds 1 and 2 significantly reduced melanin production in a dose-dependent manner with IC50 values of 13.3 and 15.5 μM, respectively. Synonyms: Desacetylinulicin. Grade: >98%. CAS No. 33620-72-3. Molecular formula: C15H22O4. Mole weight: 266.33.
BRITE 338733
BRITE 338733 is a novel ATPase inhibitor. BRITE 338733 inhibits the expression of RecA in bacteria (IC50 = 4.7 μM) for the treatment of bacterial infections. Uses: A novel atpase inhibitor for the treatment of bacterial infections. Synonyms: BCP0008025; BRITE338733; BCP 0008025; BRITE 338733; BCP-0008025; BRITE-338733; 2-(4-(5-ethylfuran-2-yl)-6-(2,2,6,6-tetramethylpiperidin-4-ylamino)pyridin-2-yl)-4-methylphenol; 2-(6-(2,2,6,6-tetramethylpiperidin-4-ylamino)-4-(5-ethylfuran-2-yl)pyridin-2-yl)-4-methylphenol. Grade: ≥98%. CAS No. 503105-88-2. Molecular formula: C27H35O2N3. Mole weight: 433.59.
BRITE-338733
BRITE-338733 is a RecA ATPase inhibitor, with an IC50 of 4.7 μM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 503105-88-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112589.
Brite Stock 150
Brite Stock 150. Category BASE OILS. Pack Sizes Bulk
Brivanib
Brivanib is the hydrolyzed form of Brivanib alaninate, which is a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2, a tyrosine kinase receptor expressed almost exclusively on vascular endothelial cells; inhibition of VEGFR2 may result in inhibition of tumor angiogenesis, inhibition of tumor cell growth, and tumor regression. Check for active clinical trials or closed clinical trials using this agent. Synonyms: BMS540215; BMS-540215; BMS 540215. CAS No. 649735-46-6. Molecular formula: C19H19FN4O3. Mole weight: 370.37756.
Brivanib
Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with an IC 50 of 25 nM, and has moderate potency against VEGFR-1 and FGFR-1, but >240-fold against PDGFR-β [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-540215. CAS No. 649735-46-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10337.
Brivanib alaninate
Brivanib alaninate is the alaninate ester of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2, a tyrosine kinase receptor expressed almost exclusively on vascular endothelial cells; inhibition of VEGFR2 may result in inhibition of tumor angiogenesis, inhibition of tumor cell growth, and tumor regression. Check for active clinical trials or closed clinical trials using this agent. Synonyms: BMS-582664; BMS582664; BMS 582664. CAS No. 649735-63-7. Molecular formula: C22H24FN5O4. Mole weight: 441.45.
Brivanib (alaninate)
Brivanib alaninate (BMS-582664) is an ATP-competitive inhibitor against VEGFR2 with an IC 50 of 25 nM; has moderate potency against VEGFR-1 and FGFR-1, but more than 240-fold against PDGFRβ [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-582664. CAS No. 649735-63-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10336.
Brivaracetam
Brivaracetam. Group: Biochemicals. Alternative Names: (αS,4R)-α-Ethyl-2-oxo-4-propyl-1-pyrrolidineacetamide; UCB 34714. Grades: Highly Purified. CAS No. 357336-20-0. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Brivaracetam-d7
Brivaracetam-d7. Group: Biochemicals. Alternative Names: (αS,4R)-α-Ethyl-2-oxo-4-propyl-1-pyrrolidineacetamide-d7; UCB 34714-d7. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Brivaracetam Impurity 104
Brivaracetam Impurity 104. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-aminobutanenitrile. CAS No. 16750-40-6. Molecular formula: C4H8N2. Mole weight: 84.12. Catalog: APB16750406.
Brivaracetam impurity 132
Brivaracetam impurity 132. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: isobutyl 2-phenylacetate. CAS No. 102-13-6. Molecular formula: C12H16O2. Mole weight: 192.25. Catalog: APB102136.
Brivaracetam Impurity 27
Brivaracetam Impurity 27. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-2-aminobutanamide hydrochloride. CAS No. 103765-03-3. Molecular formula: C4H10N2O·HCl. Mole weight: 138.596. Catalog: APB103765033.
Brivaracetam Impurity 36
Brivaracetam Impurity 36. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-4-butyldihydrofuran-2(3H)-one. CAS No. 124094-63-9. Molecular formula: C8H14O2. Mole weight: 142.20. Catalog: APB124094639.
Brivaracetam Impurity 73
Brivaracetam Impurity 73. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-isopropyldihydrofuran-2(3H)-one. CAS No. 10547-88-3. Molecular formula: C7H12O2. Mole weight: 128.17. Catalog: APB10547883.
Brivudine
Brivudine, also known as bromovinyl-deoxyuridine, is a uridine derivative and nucleoside analog with pro-apoptotic and chemosensitizing properties. In vitro, bromovinyl-deoxyuridine (BVDU) has been shown to downregulate the multifunctional DNA repair enzyme APEX nuclease 1, resulting in the inhibition of DNA repair and the induction of apoptosis. In addition, this agent may inhibit the expression of STAT3 (signal transducer and activator of transcription 3), which may result in the downregulation of vascular endothelial growth factor (VEGF). BVDU has also been found to inhibit the upregulation of chemoresistance genes (Mdr1 and DHFR) during chemotherapy. Overall, the gene expression changes associated with BVDU treatment result in the decrease or prevention of chemoresistance. In addition, this agent has been shown to enhance the cytolytic activity of NK-92 natural killer cells towards a pancreatic cancer cell line in vitro. Synonyms: (E)-5-(2-Bromovinyl)-2'-deoxyuridine; (E)-5-(2-Bromovinyl)deoxyuridine; (E)-5-O-(2-bromoethenyl)-2'-deoxyuridine; 5-[(1E)-2-Bromoethenyl]-2'-deoxyuridine; 5-[(E)-2-Bromoethenyl]-2'-deoxyuridine; BVDU; Brivudin; Bromovinyldeoxyuridine; Helpin. Grade: ≥98% by HPLC. CAS No. 69304-47-8. Molecular formula: C11H13BrN2O5. Mole weight: 333.14.
Brivudine
Brivudine is a nucloside analog which causes induction of neuronal differentiation in human reporter cell lines and adult stem cells. Anti-Herpes medication. Group: Biochemicals. Grades: Highly Purified. CAS No. 69304-47-8. Pack Sizes: 10mg, 50mg. Molecular Formula: C11H13BrN2O5, Molecular Weight: 333.14. US Biological Life Sciences.
Worldwide
Brivudine
Brivudine is a thymidine analogue with antiviral activity, indicated for the early treatment of acute herpes zoster. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Bromovinyldeoxyuridine; BVDU. CAS No. 69304-47-8. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-13578.
Brivudine 5'-Diphosphate Tristriethyl Ammonium Salt
Brivudine 5'-Diphosphate Tristriethyl Ammonium Salt is derived from Brivudine, which is a nucleoside analog which causes induction of neuronal differentiation in human reporter cell lines and adult stem cells. Anti-Herpes medication. Molecular formula: C11H15BrN2O11P2 C6H15N. Mole weight: 493.10.
Brivudine 5'-Monophosphate
Brivudine 5'-Monophosphate is a hetero-dinucleotide that acts as an anti-tumor agent against AH13 rat sarcoma cells. A nucleotide derivative which is an active species of the novel anticancer drug, NB 1011. Anti-viral. Synonyms: BVDU 5'-Monophosphate; (E)-5-(2-Bromovinyl)-2'-deoxyuridine 5'-Monophosphate; 5-[(1E)-2-Bromoethenyl]-2'-deoxy-5'-uridylic Acid; (E)-5-(2-bromoethenyl)-2'-deoxy-5'-uridylic Acid. CAS No. 80860-82-8. Molecular formula: C11H14BrN2O8P. Mole weight: 413.12.
Brivudine 5'-Triphosphate Ammonium
Brivudine 5'-Triphosphate Ammonium Salt is derived from Brivudine, which is a nucleoside analog which causes induction of neuronal differentiation in human reporter cell lines and adult stem cells. Anti-herpes medication. Synonyms: 5-(2-Bromovinyl)-2'-deoxyuridine-5'-triphosphate; [[(2R,3S,5R)-5-[5-[(E)-2-bromoethenyl]-2,4-dioxopyrimidin-1-yl]-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate; Uridine 5'-(tetrahydrogen triphosphate), 5-(2-bromoethenyl)-2'-deoxy-, (E)-; BVdUTP; BV(5)Dutp; Bvdu-tp; SCHEMBL442341; SCHEMBL442343; CHEMBL4594370; (E)-5-(2-Bromovinyl)-dUTP; Brivudine 5'-Triphosphate Ammonium; E-5-Bromovinyl-2'-deoxyuridine triphosphate; (E)-5-(2-Bromovinyl)-2'-deoxyuridine triphosphate; (e)-5-(2-bromovinyl)-2'-deoxyuridine 5'-triphosphate; Uridine 5'-(tetrahydrogen triphosphate), 5-[(1E)-2-bromoethenyl]-2'-deoxy-; ((2R,3S,5R)-5-(5-((E)-2-Bromovinyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate; [[(2R,3S,5R)-5-[5-[(E)-2-bromovinyl]-2,4-dioxo-pyrimidin-1-yl]-3-hydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate. Molecular formula: C11H16BrN2O14P3. Mole weight: 573.08.
Brivudine Impurity 11
Brivudine Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1053650-23-9. Molecular formula: C25H20Br2Cl2N2O7. Mole weight: 691.15. Catalog: APB1053650239.
Brivudine Impurity 16
Brivudine Impurity 16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 113890-35-0. Molecular formula: C5H10O4. Mole weight: 134.13. Catalog: APB113890350.
Brivudine Impurity 17
Brivudine Impurity 17. Uses: For analytical and research use. Group: Impurity standards. CAS No. 122776-03-8. Molecular formula: C10H16ClNO3. Mole weight: 233.69. Catalog: APB122776038.
Brivudine Impurity 19
Brivudine Impurity 19. Uses: For analytical and research use. Group: Impurity standards. CAS No. 113890-38-3. Molecular formula: C5H10O4. Mole weight: 134.13. Catalog: APB113890383.
Brivudine Impurity 22
Brivudine Impurity 22. Uses: For analytical and research use. Group: Impurity standards. CAS No. 18546-37-7. Molecular formula: C5H10O4. Mole weight: 134.13. Catalog: APB18546377.
Brivudine Impurity ((E)-5-(2-Bromovinyl)uracil )
Brivudine Impurity ((E)-5-(2-Bromovinyl)uracil) is an impurity commonly found in Brivudine. Brivudine is an antiviral drug used to treat herpes zoster (shingles) and genital herpes. Synonyms: 5-[(1E)-2-Bromoethenyl]-2,4(1H,3H)-pyrimidinedione. Grade: > 95%. CAS No. 69304-49-0. Molecular formula: C6H5BrN2O2. Mole weight: 217.02.
BRL-15,572 is selective 5-HT1D antagonist with around 60x selectivity over other related receptors. It is a useful tool for the differentiation between human 5-HT1B and 5-HT1D receptors in functional studies. Uses: Serotonin 5-ht1 receptor antagonists. Synonyms: RL 15572; RL15572; RL-15572; 1-(Diphenylmethyl)-2-(4-(3-chlorophenyl)-1-piperazinyl)ethanol; 193611-72-2 (HCl). Grade: 98%. CAS No. 734517-40-9. Molecular formula: C25H27ClN2O. Mole weight: 406.95.
BRL-15572 dihydrochloride
BRL-15572 displays high affinity and selectivity for h5-HT1D receptors. BRL-15572 has 60-fold higher affinity for h5-HT1D than 5-HT1B receptors. Uses: Serotonin 5-ht1 receptor antagonists. Synonyms: BRL-15572; BRL 15572; BRL15572. Grade: >98%. CAS No. 193611-72-2. Molecular formula: C25H27ClN2O.2HCl. Mole weight: 479.87.
BRL-15572 dihydrochloride
BRL-15572 dihydrochloride is a selective antagonist of h5-HT1D , displays high affinity for h5-HT1D receptors. BRL-15572 dihydrochloride could be useful pharmacological agents to characterise 5-HT1D receptor mediated responses [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 193611-72-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13200.
BRL 15572 hydrochloride
BRL 15572 hydrochloride is a selective h5-HT1D antagonist with 60-fold selectivity over h5-HT1B. Synonyms: BRL 15572 hydrochloride; BRL15572 hydrochloride; BRL-15572 hydrochloride; 3-[4-(4-Chlorophenyl)piperazin-1-yl]-1,1-diphenyl-2-propanol hydrochloride. CAS No. 1173022-77-9. Molecular formula: C25H27ClN2O.HCl. Mole weight: 443.42.
BRL-37344
BRL-37344 is a new, highly specific, beta 3-adrenergic receptor radioligand. Synonyms: 2-(4-((2R)-2-(((2R)-2-(3-Chlorophenyl)-2-hydroxyethyl)amino)propyl)phenoxy)acetic acid; SB-206606; BRL 37344. CAS No. 114333-71-0. Molecular formula: C19H22ClNO4. Mole weight: 363.84.
BRL-37344
BRL-37344 (Fosigotifator (THAM sodium)) is a specific β3-adrenergic receptor agonist. BRL-37344 treatment significantly lowers the body weight of obese mice [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 90730-96-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-101325A.
BRL 37344 sodium
BRL 37344 sodium (BRL 37344A) is a specific β3-adrenergic receptor agonist. BRL 37344 sodium treatment significantly lowers the body weight of obese mice [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BRL 37344A. CAS No. 127299-93-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-101325.
BRL-37344 sodium
BRL37344 is a selective β3-adrenergic receptor agonist originated by GlaxoSmithKline. Ki value is 287nM for β3 receptor, 1750nM for β1 receptor and 1120nM for β2 receptor. BRL37344 can decrease nerve-evoked contractions in human detrusor smooth muscle isolated strips, it can also stimulate fuel oxidation by soleus muscle in vitro. BRL37344 increases glucose transport into L6 myocytes through a mechanism different from that of insulin. But preclinical for Diabetes mellitus was discontinued. Uses: Diabetes mellitus. Synonyms: BRL-37344 sodium; BRL 37344 sodium; BRL37344 sodium; sodium; 2-[4-[(2R)-2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]phenoxy]acetate. Grade: 98 %. CAS No. 127299-93-8. Molecular formula: C19H21ClNNaO4. Mole weight: 385.82.
BRL44385
BRL44385, a novel guanine analogue, is a potent and selective inhibitor of herpes simplex virus types 1 and 2 and varicella zoster virus. Synonyms: 2-amino-9-(3-hydroxypropoxy)-3H-purin-6-one; 9-(3-hydroxypropoxy)guanine; BRL 44385; BRL-44385. Grade: >98%. CAS No. 114778-60-8. Molecular formula: C8H11N5O3. Mole weight: 225.2.
BRL 44408
BRL 44408 is a selective α2A-adrenoceptor antagonist (Ki = 1.7 nM and 144.5 nM at α2A and α2B-adrenergic receptors, respectively). BRL 44408 increases hippocampal noradrenalin release following systemic administration. Uses: Selective α2a-adrenoceptor antagonist. increases hippocampal noradrenaline release following systemic administration. Synonyms: 2-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-2,3-dihydro-1-methyl-1H-isoindole; 1H-Isoindole, 2-[(4,5-dihydro-1H-imidazol-2-yl)methyl]-2,3-dihydro-1-methyl-. Grade: ≥95%. CAS No. 118343-19-4. Molecular formula: C17H21N3O4. Mole weight: 331.37.
BRL 44408
Selective α2A-adrenoceptor antagonist. Increases hippocampal noradrenaline release following systemic administration. Group: Biochemicals. Alternative Names: 2-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-2,3-dihydro-1-methyl-1H-isoindole. Grades: Highly Purified. CAS No. 118343-19-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
BRL-44408 maleate
BRL-44408 maleate is an α2A-adrenoceptor antagonist ( K i : 8.5 nM). BRL-44408 maleate has antidepressant and analgesic activity. BRL-44408 also improves cecal ligation puncture (CLP)-induced acute lung injury [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 681806-46-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-12716A.
BRL 44408 Maleate
BRL 44408 maleate is a selective α2A-adrenoceptor antagonist (Ki = 1.7 nM and 144.5 nM at α2A and α2B-adrenergic receptors, respectively). BRL 44408 increases hippocampal noradrenalin release following systemic administration. Synonyms: 2-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-2,3-dihydro-1-methyl-1H-isoindole maleate; 1H-Isoindole, 2-[(4,5-dihydro-1H-imidazol-2-yl)methyl]-2,3-dihydro-1-methyl-, (2Z)-2-butenedioate (1:1). Grade: ≥98% by HPLC. CAS No. 681806-46-2. Molecular formula: C17H21N3O4. Mole weight: 331.37.
A selective alpha-2A-adrenoceptor antagonist (Ki = 1.7nM and 144.5nM at alpha-2A and alpha-2B-adrenergic receptors respectively). Has been used to study regulation of neurotransmitter release from sympathetic nerves and shown to increase hippocampal noradrenaline release following systemic administration. Group: Biochemicals. Grades: Highly Purified. CAS No. 118343-19-4. Pack Sizes: 10mg. Molecular Formula: C??H??N?; C?H?O?. US Biological Life Sciences.
BRL 50481 is a potent, selective substrate-competitive inhibitor of phosphodiesterase (PDE) 7 (Ki = 180 nM). Uses: A pde7 inhibitor that has acceptable selectivity for in vivo studies. Synonyms: BRL-50481; BRL 50481; BRL50481. 3-(N,N-Dimethylsulfonamido)-4-methylnitrobenzene, 5-Nitro-2-N,N-trimethylbenzenesulfonamide. Grade: ≥95%. CAS No. 433695-36-4. Molecular formula: C9H12N2O4S. Mole weight: 244.27.
BRL-50481 is a novel and selective inhibitor of PDE7 with IC 50 s of 0.15, 12.1, 62 and 490 μM for PDE7A , PDE7B , PDE4 and PDE3 , respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 433695-36-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109586.
BRL-50481
BRL-50481. Group: Biochemicals. Alternative Names: 3-(N,N-Dimethylsulfonamido)-4-methylnitrobenzene, 5-nitro-2-N, N-trimethyl Benzene sulfonamide. Grades: Highly Purified. CAS No. 433695-36-4. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C9H12N2O4S. US Biological Life Sciences.
A PDE7 inhibitor that has acceptable selectivity for in vivo studies. Group: Biochemicals. Alternative Names: 3-(N,N-Dimethylsulfonamido)-4-methylnitrobenzene, 5-Nitro-2-N, N-trimethyl Benzene sulfonamide. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.