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| Product | Description | |
|---|---|---|
| Butyronitrile diethyl malonate | Butyronitrile diethyl malonate. Group: Biochemicals. Alternative Names: Diethyl-3-cyanopropylmalonate; 2- (3-Cyanopropyl) propanedioic acid 1,3-diethyl ester. Grades: Highly Purified. CAS No. 63972-18-9. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C11H17NO4. US Biological Life Sciences. |  Worldwide |
| Butyronitrile Diethyl Malonate (Diethyl-3-cyanopropylmalonate) | Butyronitrile Diethyl Malonate (Diethyl-3-cyanopropylmalonate). Group: Biochemicals. Alternative Names: Diethyl-3-cyanopropylmalonate. Grades: Highly Purified. Pack Sizes: 2.5g. US Biological Life Sciences. | Worldwide |
| Butyrophenone | Butyrophenone is used as an antipsychotic drug in pharmacotherapy. Group: Biochemicals. Alternative Names: 1-Phenyl-1-butanone; 1-Benzoylpropane; 1-Phenyl-1-butanone; Butanophenone; NSC 8463; Phenyl n-Propyl Ketone; Phenyl Propyl Ketone; Propyl Phenyl Ketone; n-Butyrophenone; n-Propyl Phenyl Ketone. Grades: Highly Purified. CAS No. 495-40-9. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| Butyrophenone | analytical standard. Group: Flavor and fragrance standards. |  |
| Butyrospermum Parkii (Shea Butter) | Sheatree, Butyrospermum parkii, also known as Vitellaria paradoxa, is the source of Butyrospermum Parkii (Shea) Butter. When raw, it is ivory in colour and is frequently coloured yellow with palm oil or borutu root. It is used in numerous cosmetic and personal care products, such as bath and cleaning products, eye makeup, lotions and creams, suntan products, lipstick, and hair care products, where it functions as emollients and viscosity controllers. Uses: 1. moisturizer - shea butter is a natural emollient that helps to lock in moisture and improve skin hydration. it is easily absorbed into the skin and does not leave a residue. 2. anti-inflammatory - shea butter contains cinnamic acid, which has been shown to have anti-inflammatory properties. this makes it helpful in treating inflammatory skin conditions like acne, eczema, and psoriasis. 3. anti-. Additional or Alternative Names: BUTYROSPERMUM PARKII (SHEA BUTTER);Fats and Glyceridic oils, shea butter;BUTYROSPERMUM PARKII (SHEA BUTTER LIQUID);SHEA BUTTER BUTYROSPERMUM PARKII. Product Category: Heterocyclic Organic Compound. CAS No. 194043-92-0. Product ID: ACM194043920. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Butyrylcarnitine | Butyrylcarnitine is a metabolite in plasma, acts as a biomarker to improve the diagnosis and prognosis of heart failure, and is indicative of anomalous lipid and energy metabolism. Uses: Scientific research. Group: Natural products. CAS No. 25576-40-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113168. |  |
| Butyryl chloride | Pharma Intermediates. CAS No. 141-75-3. Categories: butanoyl chloride, n- butyrylchloride, butyric acid chloride, butyric chloride. |  US, Austria, Lithuania |
| Butyryl Chloride | Butyryl Chloride. Group: Biochemicals. Alternative Names: Butyryl Chloride; Butanoic Acid Chloride; Butyric Acid Chloride; Butyric Chloride; Butyroyl Chloride; n-Butanoyl Chloride; n-Butyroyl Chloride; n-Butyryl Chloride. Grades: Highly Purified. CAS No. 141-75-3. Pack Sizes: 5g. Molecular Formula: C4H7ClO, Molecular Weight: 106.55. US Biological Life Sciences. | Worldwide |
| Butyrylcholine chloride | 25g Pack Size. Group: Building Blocks, Organics. Formula: C9H20ClNO2. CAS No. 2963-78-2. Prepack ID 49629139-25g. Molecular Weight 209.71. See USA prepack pricing. |  |
| Butyrylcholine chloride | Butyrylcholine (chloride) is a biochemical assay reagent. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 2963-78-2. Pack Sizes: 50 mg. Product ID: HY-W014419. | |
| Butyrylcholine Chloride | Butyrylcholine Chloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 2963-78-2. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences. | Worldwide |
| Butyrylcholine iodide | Butyrylcholine Iodide is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 2494-56-6. Pack Sizes: 100 mg. Product ID: HY-W009236. | |
| Butyrylcholine perchlorate | Butyrylcholine perchlorate, a potent biomedical compound, finds its application in both research and clinical environments. Serving as an acetylcholine receptor agonist, this cholinergic substance bravely delves into unraveling the intricate mechanisms governing cholinergic neurotransmission. With an unwavering dedication to scientific exploration, it illuminates the enigmatic role played by this neurotransmission in afflictions such as Alzheimer's disease, myasthenia gravis, and an array of formidable neuromuscular disorders. Synonyms: BUTYRYLCHOLINE PERCHLORATE; Trimethyl(2-(1-oxobutoxy)ethyl)ammonium perchlorate; EINECS 243-700-3; 2-butanoyloxyethyl(trimethyl)azanium; perchlorate; 566ZY7YY3K; DTXSID80174172; [2-(butanoyloxy)ethyl]trimethylazanium perchlorate; Ethanaminium, N,N,N-trimethyl-2-(1-oxobutoxy)-, perchlorate; Ethanaminium, N,N,N-trimethyl-2-(1-oxobutoxy)-, perchlorate (1:1). CAS No. 20292-68-6. Molecular formula: C9H20ClNO6. Mole weight: 273.71. |  |
| Butyryl-Coenzyme A lithium hydrate | Butyryl-Coenzyme A lithium hydrate can synthesize Butyric acid (HY-B0350) or Butyrate [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Butyryl CoA lithium hydrate. CAS No. 1107039-35-9. Pack Sizes: 500 μg; 1 mg. Product ID: HY-141479B. | |
| Butyryl coenzyme A lithium salt hydrate | ?90%. Group: Fluorescence/luminescence spectroscopy. | |
| Butyrylhydroxamic acid | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Butyryl-L-carnitine chloride | (R)-Butyryl Carnitine is a potential prodrug of Carnitine, via the carnitine transporter OCTN2 and the amino acid transporter ATB0,+. It is an inhibitor of intestinal transporters, which block carnitine uptake by the carnitine transporter with IC50s of 1.5 μM and glycine transport with IC50s of 4.6 μM in in human retinal pigment epithelial (HRPE) cells. Butyryl-L-carnitine is used for treating seizure disorders. Synonyms: L-Butyrylcarnitine; C4 Carnitine. Grades: ≥95%. CAS No. 162067-50-7. Molecular formula: C11H22NO4·Cl. Mole weight: 267.8. | |
| Butyryl-L-carnitine chloride 98+% (TLC) | Butyryl-L-carnitine chloride 98+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 25mg, 100mg, 250mg. US Biological Life Sciences. | Worldwide |
| Butyryl-L-carnitine-d3 chloride | Butyryl-L-carnitine-d 3 (chloride) is the deuterium labeled Butyryl-L-carnitine chloride[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1334532-21-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-115704S1. | |
| Butyryl Phosphate Dilithium Salt | Butyryl phosphate has a role in metabolism. Group: Biochemicals. Alternative Names: Butanoic Acid Phosphono Ester Dilithium Salt; Butanoyl Phosphate Dilithium Salt. Grades: Highly Purified. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
| Butyrylthiocholine chloride | 1g Pack Size. Group: Analytical Reagents, Biochemicals, Building Blocks, Diagnostic Raw Materials, Organics. Formula: C9H20ClNOS. CAS No. 22026-63-7. Prepack ID 26608039-1g. Molecular Weight 225.78. See USA prepack pricing. | |
| Butyrylthiocholine iodide | 5g Pack Size. Group: Building Blocks, Organics. Formula: C9H20INOS. CAS No. 1866-16-6. Prepack ID 34904481-5g. Molecular Weight 317.23. See USA prepack pricing. | |
| Buxtamine (Buxtauine, Cyclobuxoxine) | Buxtamine (Buxtauine, Cyclobuxoxine). Group: Biochemicals. Alternative Names: Buxtauine M; Cyclomicrobuxinine; Cyclobuxoxine. Grades: Plant Grade. CAS No. 4236-73-1. Pack Sizes: 10mg. Molecular Formula: C24H37NO2, Molecular Weight: 371.555999999999. US Biological Life Sciences. | Worldwide |
| Buxtauine | Buxtauine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Buxtauine. Product Category: Heterocyclic Organic Compound. CAS No. 4236-73-1. Molecular formula: C24H37NO2. Mole weight: 371.56. Product ID: ACM4236731. Alfa Chemistry ISO 9001:2015 Certified. Categories: Buxtamine. | |
| BV02 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BV6 | BV-6 is a selective inhibitor of apoptosis (IAP) family with IC50 value of 7.2 μM when tested with H460 cells. It acts by promoting glioblastoma cancer stem-like cell differentiation by activating NF-κB. BV-6 induces autoubiquitination and proteasomal degradation of IAP1 and XIAP in MDA-MB-231 cells at 5 μM. In BALB/c mice model with transplanted abdominal cavities from donor mouse uterine tissue, intraperitoneally with BV-6 repressed the advancement of endometriosis, cell proliferative activity via inhibiting the expression of IAPs. In hematological THP-1 cells, pre-treatment with BV-6 increased the CIK cells killing ability and the same results were achieved in solid malignancy RH30 cells. Grades: ≥98%. CAS No. 1001600-56-1. Molecular formula: C70H96N10O8. Mole weight: 1205.57. | |
| Bvacado Oil microencapsulated powder | Bvacado Oil microencapsulated powder. Product ID: CDF4-0212. Molecular formula: NA. Category: Nutrient supplements. Product Keywords: Food Ingredients; Nutrients; CDF4-0212; Bvacado Oil microencapsulated powder; Nutrient supplements. Appearance: White to light yellow powder. Color: White to light yellow. Physical State: powder. Source and Preparation: Bvacado. Applications: Dietary supplements, nutritional supplements, cosmetic raw materials, etc. |  |
| BVD 10 | BVD 10 is a selective NPY Y1 receptor antagonist (Ki = 25.7, 1420, 2403 and 7100 nM at Y1, Y2, Y4 and Y5 receptors, respectively) with no activity at Y4 receptors. Synonyms: BVD 10; BVD10; BVD-10. Grades: >98%. CAS No. 262418-00-8. Molecular formula: C58H92N16O13. Mole weight: 1221.46. | |
| BVFP | BVFP binds to the PGRN 588 - 593 peptide with a K d of 20 μM. BVFP can disrupt PGRN-SORT1 binding. BVFP also inhibits SORT1-mediated rPGRN endocytosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 357158-20-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 1100 mg. Product ID: HY-153686. | |
| BVT.13 hydrate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BVT-14225 | BVT-14225 is a highly selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor(IC50 = 52 nM), which is 1,000 fold lower than that for 11β-HSD2. Synonyms: 2-[2-[(3-chloro-2-methylphenyl)sulfonylamino]-1,3-thiazol-4-yl]-N,N-diethylacetamide; BVT-14225; BVT 14225; BVT14225. CAS No. 376638-65-2. Molecular formula: C16H20ClN3O3S2. Mole weight: 401.93. | |
| BVT 2733 | BVT 2733 is a non-steroidal small molecule as a selective 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor (IC = 96 ± 14 nM). Synonyms: BVT-2733; BVT 2733; BVT2733; 3-chloro-2-methyl-N-(4-(2-(4-methylpiperazin-1-yl)-2-oxoethyl)thiazol-2-yl)benzenesulfonamide; Piperazine, 1-((2-(((3-chloro-2-methylphenyl)sulfonyl)amino)-4-thiazolyl)acetyl)-4-methyl-. Grades: 98%. CAS No. 376640-41-4. Molecular formula: C17H21ClN4O3S2. Mole weight: 428.95. | |
| BVT.2733 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BVT 2733 hydrochloride | BVT 2733 hydrochloride is a selective inhibitor of 11β-hydroxysteroid dehydrogenase type 1. Synonyms: BVT 2733 hydrochloride; BVT2733 hydrochloride; BVT-2733 hydrochloride; 3-chloro-2-methyl-N-[4-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-1,3-thiazol-2-yl]benzenesulfonamide hydrochloride. Grades: 99%. CAS No. 376641-65-5. Molecular formula: C17H21ClN4O3S2.HCl. Mole weight: 465.42. | |
| BVT 948 | BVT 948. Group: Biochemicals. Grades: Purified. CAS No. 39674-97-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BVT-948 | BVT 948 is a non-competitive and cell-permeable inhibitor of protein tyrosine phosphatases (PTPs) (IC50 = 0.09 - 1.7 μM). BVT 948 displays irreversible inhibition through catalysis of the hydrogen peroxide-dependent oxidation of PTP, and enhances insulin signaling in vitro and insulin tolerance in ob/ob mice in vivo. Some cytochrome P450 isoforms are also suppressed by BVT 948 (IC50 <10 μM). Synonyms: BVT948; BVT-948; BVT 948; SPS8I3; SPS-8I3; SPS 8I3; 4-Hydroxy-3,3-dimethyl-2H-benz[g]indole-2,5(3H)-dione. Grades: ≥98% by HPLC. CAS No. 39674-97-0. Molecular formula: C14H11NO3. Mole weight: 241.24. | |
| BVT.948 | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| BW 245C | BW 245C, a prostaglandin analogue, is a selective prostanoid DP-receptor (DP1) agonist used to treat stroke where the Ki for the inhibition of [3H]-PGD2 binding to isolated human platelet membranes is 0.9 nM and has a reported IC50 of 2.5 nM for the inhibition of ADP-induced human platelet aggregation. Synonyms: 7-[(4S)-3-[(3R)-3-cyclohexyl-3-hydroxypropyl]-2,5-dioxoimidazolidin-4-yl]heptanoic acid; 245C77; 5-(6-carboxyhexyl)-1-(3-cyclohexyl-3-hydroxypropyl)hydantoin; BW 245C; BW 245C, (R*,S*)-(+-); BW-245C. CAS No. 72814-32-5. Molecular formula: C19H32N2O5. Mole weight: 368.47. | |
| BW 246C | The prostaglandin D2 (PGD2) receptors are the members of G protein-coupled receptors. PGD2 receptors include the following proteins prostaglandin D2 receptor 1 (DP1) and prostaglandin D2 receptor 2 (DP2). BW 246C is a DP receptor agonist. BW 246C is the less active C-8 diastereomer of the DP receptor agonist BW 245C. The activity of BW 245C is 70-fold greater than that of BW 246C. Synonyms: 8-epi BW 245C. Grades: ≥98%. CAS No. 65705-83-1. Molecular formula: C19H32N2O5. Mole weight: 368.5. | |
| BW 373U86 | BW 373U86 is a potent and selective non-peptide δ-opioid receptor agonist (Ki = 1.8, 15 and 34 nM for δ, μ and κ receptors, respectively). Synonyms: BW-373U86; SNC-86; BW 373U86; SNC 86; BW373U86; SNC86; 4-[(αR)-α-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-hydroxybenzyl]-N,N-diethylbenzamide. Grades: ≥99% by HPLC. CAS No. 155836-50-3. Molecular formula: C27H37N3O2. Mole weight: 435.61. | |
| BW 723C86 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BW-723C86 | BW-723C86 is an orally active and a selective 5-HT 2B receptor agonist. BW-723C86 exhibits anxiolytic-like actions. BW-723C86 also causes hyperphagia and reduced grooming in rats. BW-723C86 dilates pulmonary arteries and inhibits liquid meal-induced gastric accommodation [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 160521-72-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101369. | |
| BW 723C86 hydrochloride | BW 723C86 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 160521-72-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BW 723C86 hydrochloride | BW 723C86 hydrochloride is a selective 5-HT2B receptor agonist used for the treatment of certain CNS disorders, such as epilepsy, migraine and feeding disorders. Uses: The treatment of cns disorders as epilepsy, migraine and feeding disorders. Synonyms: BW723C86; BW-723-C-86; BW 723 C 86; BW-723C86; BW 723C86; α-methyl-5-(2-thienylmethoxy)-1H-indole-3-ethanamine hydrochloride. Grades: ≥99% by HPLC. CAS No. 160521-72-2. Molecular formula: C16H18N2OS.HCl. Mole weight: 322.85. | |
| BW 755C | Constitutive cyclooxygenase (COX-1) is present in cells under physiological conditions, whereas COX-2 is induced by some cytokines, mitogens, and endotoxin in pathological conditions, such as inflammation. Since 5-lipoxygenase (5-LO) oxidizes arachidonic acid to 5-hydroperoxyeicosatetraenoic acid. BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways. It inhibits 5-LO with IC50s of 0.75 μM, COX-1 with IC50s of 0.65 μg/ml, and COX-2 with IC50s of 1.2 μg/ml. BW 755C may also inhibit other LO pathways in vivo. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: BW755C; BW-755C; 1H-Pyrazol-3-amine, 4,5-dihydro-1-[3-(trifluoromethyl)phenyl]-; 4,5-Dihydro-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-3-amine; 1-(3-Trifluoromethylphenyl)-4,5-dihydro-1H-pyrazol-3-amine; 3-Amino-1-[3-(trifluoromethyl)phenyl]-2-pyrazoline; 3-Amino-1-[3-(trifluoromethyl)phenyl]pyrazoline; 3-Amino-1-[m-(trifluoromethyl)phenyl]-2-pyrazoline; Compound BW 755C. Grades: ≥95%. CAS No. 66000-40-6. Molecular formula: C10H10F3N3. Mole weight: 229.20. | |
| BW A4C | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BW-A78U | BW-A 78U is a PDE4 inhibitor with an IC50 of 3 μM. BW-A 78U fails to significantly inhibit arachidonate release. It is ineffective to inhibit the lipopolysaccharide (LPS)-induced TNF-α release. Synonyms: BW A78U. Grades: ≥98%. CAS No. 101155-02-6. Molecular formula: C13H12FN5. Mole weight: 257.27. | |
| BW A868C | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BW A868C | Prostaglandin D2 (PGD2) has been widely distributed in rat brain, spinal cord and pituitary and may act as a neuromodulator in the central nervous system. BW A868C is a novel, selective and potent competitive antagonist of PGD2. BW A868C antagonizes the prostaglandin D2 and BW 245C-induced activation of human platelet adenylate cyclase. BW A868C antagonizes the accumulation of cAMP in rabbit non-pigmented ciliary epithelial cells. However, it has virtually no effect on human TP, IP, EP1, EP2, and FP receptors. Synonyms: BWA-868C; BWA868C. Grades: ≥98%. CAS No. 118675-50-6. Molecular formula: C25H37N3O5. Mole weight: 459.6. | |
| BW B70C | >98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| BW-B 70C | BW B70C is a potent and selective inhibitor of 5-lipoxygenase (5-LO). 5-LO is an enzyme that transforms essential fatty acids (EFAs) into leukotrienes and is activated by 5-lipoxygenase activating protein (FLAP). BW-B 70C had high potency and long duration in vivo and was considered as potential anti-asthma drug. It was reported that BW B70C blocks leukotriene C4 synthesis by alveolar macrophages, which decreases the migration for leukocyte to the airway lumen. BW B70C didn't affect vascular leucocyte margination and the blood levels of secreted phospholipase A2 and TNF-&alpha. Synonyms: N-[3-[3-(-Fluorophenoxy)phenyl]-1-methyl-2-propenyl]-N-hydroxyurea. Grades: ≥98%. CAS No. 134470-38-5. Molecular formula: C17H17FN2O3. Mole weight: 316.33. | |
| BW-B 70C | BW-B 70C. Group: Biochemicals. Grades: Purified. CAS No. 134470-38-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BWX 46 | BWX 46. Group: Biochemicals. Grades: Purified. CAS No. 172997-92-1. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| BX-320 | BX-320 is a selective, ATP-competitive, orally acitive, and direct PDK1 inhibitor with an IC 50 of 30 nM in a direct kinase assay format. BX-320 also induces apoptosis. Anticancer effect [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 702676-93-5. Pack Sizes: 1 mg. Product ID: HY-10515. | |
| BX341 | BX341, also known as bifluranol, is a new fluorinated bibenzyl anti-androgen and one of a series of bibenzyls designed to present some of the hormonal properties of diethylstilboestrol (DES) but with a lower potential for toxicity. Synonyms: BX341; BX 341; BX-341; 2-fluoro-4-[3-(3-fluoro-4-hydroxyphenyl)pentan-2-yl]phenol; bifluranol; erythro-2,3-bis(3-fluor-4-hydroxyphenyl)pentan. CAS No. 34633-34-6. Molecular formula: C17H18F2O2. Mole weight: 292.32. | |
| BX430 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BX 430 | BX 430 is a selective P2X4 allosteric antagonist (IC50 = 0.54 μM) binding noncompetitively to extracellular allosteric site. It exhibits >10-fold selectivity for human P2X4 receptors over P2X1, P2X2, P2X3, P2X5 and P2X7 receptors. BX 430 is inactive at mouse and rat P2X4 receptors. Synonyms: BX430; BX-430; BX 430; N-[2,6-Dibromo-4-(1-methylethyl)phenyl]-N'-(3-pyridinyl)urea. Grades: ≥99% by HPLC. CAS No. 688309-70-8. Molecular formula: C15H15Br2N3O. Mole weight: 413.11. | |
| BX471 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BX 471 | BX 471 is a selective CCR1 antagonist. Synonyms: (R)-1-(5-chloro-2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-2-oxoethoxy)phenyl)urea; BX471; BX 471; BX-471; ZK811752; ZK 811752; ZK-811752. CAS No. 217645-70-0. Molecular formula: C21H24ClFN4O3. Mole weight: 434.89. | |
| BX 471 | BX 471. Group: Biochemicals. Grades: Purified. CAS No. 217645-70-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BX-471 | BX-471, also known as ZK-811752, is a potent, selective non-peptide CCR1 antagonist (Ki = 1 nM for human CCR1). BX-471 exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4. BX-471 was developed Berlex and its parent company, Schering AG. BX-471 is the lead in a series of non-peptide chemokine receptor 1 (CCR1) antagonists, for the potential treatment of autoimmune diseases, in particular multiple sclerosis (MS). In March 2000, BX-471 was undergoing phase I trials for the potential treatment of autoimmune diseases. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BX471; BX 471; BX-471; ZK811752; ZK 811752; ZK-811752. Product Category: Antagonists. Appearance: Solid powder. CAS No. 217645-70-0. Molecular formula: C21H24ClFN4O3. Mole weight: 434.89. Purity: >98%. IUPACName: (R)-1-(5-chloro-2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-2-oxoethoxy)phenyl)urea. Canonical SMILES: C[C@H]1N(C(COC2=CC=C(Cl)C=C2NC(N)=O)=O)CCN(CC3=CC=C(F)C=C3)C1. Product ID: ACM217645700. Alfa Chemistry ISO 9001:2015 Certified. Categories: Bx41 (New York City bus). | |
| BX471 hydrochloride | BX471 hydrochloride is a potent, selective non-peptide CCR1 antagonist (Ki = 1 nM for human CCR1). Synonyms: BX-471 hydrochloride; BX 471 hydrochloride; (R)-1-(5-chloro-2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-2-oxoethoxy)phenyl)urea hydrochloride. CAS No. 288262-96-4. Molecular formula: C21H25Cl2FN4O3. Mole weight: 471.35. | |
| BX471 (N-[5-chloro-2-[2-[(2R)-4-[(4-fluorophenyl)methyl]-2-methyl-1-piperazinyl]-2-oxoethoxy]phenyl]-urea, ZK-811752) | An orally active, selective antagonist for chemokine receptor 1 (CCR-1) (Ki = 1-5nM). Has been used in studies related to intracellular calcium mobilization and migration of leukocytes mediated through CCR-1. Group: Biochemicals. Grades: Highly Purified. CAS No. 217645-70-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| BX 513 hydrochloride | BX 513 hydrochloride is a selective CCR1 receptor antagonist (Ki = 0.04, > 10, > 10 and > 10 nM for CCR1, CCR5, CXCR2 and CXCR4 receptors, respectively), and also acts as a US28 agonist. It inhibits MIP-1α-induced intracellular calcium mobilization (IC50 = 2.5 μM). Synonyms: BX-513 hydrochloride; BX513 hydrochloride; 1-Piperidinepentanenitrile, 4-(4-chlorophenyl)-4-hydroxy-α,α-diphenyl-, hydrochloride (1:1); 4-(4-Chlorophenyl)-4-hydroxy-α,α-diphenyl-1-piperidinepentanenitrile hydrochloride; VUF 2274 hydrochloride; 5-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidyl]-2,2-diphenyl-pentanenitrile hydrochloride. Grades: ≥99% by HPLC. CAS No. 1216540-18-9. Molecular formula: C28H29ClN2O.HCl. Mole weight: 481.46. | |
| BX 513 hydrochloride | BX 513 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1216540-18-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BX-517 | BX-517, also known as PDK1 inhibitor2, is a cell-permeable indolinone compound that acts as a potent, ATP site-targeting PDK1 inhibitor (IC50 = 6 nM). BX-517 also blocks activation of Akt in tumor cells with 10-fold more potent (IC50 = 0.1-1.0 μM) than its analogs tested at the highest dose tested (10 μM). Synonyms: (Z)-N-(3-(1-(1H-pyrrol-2-yl)ethylidene)-2-hydroxy-3H-indol-5-yl)carbamimidic acid; BX-517; BX 517; BX517; PDK1 inhibitor2. CAS No. 850717-64-5. Molecular formula: C15H14N4O2. Mole weight: 282.3. | |
| BX795 | BX795 Inhibitor. Uses: Scientific use. Product Category: T1830. CAS No. 702675-74-9. |  |
| BX 795 | BX 795. Group: Biochemicals. Grades: Purified. CAS No. 702675-74-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BX-795 | 3-Phosphoinositide-dependent protein kinase 1 (PDK1) is a serine-threonine kinase that phosphorylates and activates a range of other kinases, including PKB, PKA, and certain isoforms of PKC. BX795 is a potent and specific PDK1 inhibitor with IC50 of 6 nM, which is 140- and 1600-fold more selective than PKA and PKC. It is also a potent and relatively specific inhibitor of TBK1 with IC50 of 6 nM and IKK? with IC50 of 41 nM. Synonyms: BX 795; BX795. Grades: ≥98%. CAS No. 702675-74-9. Molecular formula: C23H26IN7O2S. Mole weight: 591.47. | |
| BX-795 hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
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