A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
BVT948 is a protein tyrosine phosphatase (PTP) inhibitor which can also inhibit several cytochrome P450 (P450) isoforms and lysine methyltransferase SETD8 (KMT5A). Uses: Scientific research. Group: Signaling pathways. CAS No. 39674-97-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100625.
BVT 948
BVT 948. Group: Biochemicals. Grades: Purified. CAS No. 39674-97-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
BVT-948
BVT 948 is a non-competitive and cell-permeable inhibitor of protein tyrosine phosphatases (PTPs) (IC50 = 0.09 - 1.7 μM). BVT 948 displays irreversible inhibition through catalysis of the hydrogen peroxide-dependent oxidation of PTP, and enhances insulin signaling in vitro and insulin tolerance in ob/ob mice in vivo. Some cytochrome P450 isoforms are also suppressed by BVT 948 (IC50 <10 μM). Synonyms: BVT948; BVT-948; BVT 948; SPS8I3; SPS-8I3; SPS 8I3; 4-Hydroxy-3,3-dimethyl-2H-benz[g]indole-2,5(3H)-dione. Grade: ≥98% by HPLC. CAS No. 39674-97-0. Molecular formula: C14H11NO3. Mole weight: 241.24.
BW 245C, a prostaglandin analogue, is a selective prostanoid DP-receptor (DP1) agonist used to treat stroke where the Ki for the inhibition of [3H]-PGD2 binding to isolated human platelet membranes is 0.9 nM and has a reported IC50 of 2.5 nM for the inhibition of ADP-induced human platelet aggregation. Synonyms: 7-[(4S)-3-[(3R)-3-cyclohexyl-3-hydroxypropyl]-2,5-dioxoimidazolidin-4-yl]heptanoic acid; 245C77; 5-(6-carboxyhexyl)-1-(3-cyclohexyl-3-hydroxypropyl)hydantoin; BW 245C; BW 245C, (R*,S*)-(+-); BW-245C. CAS No. 72814-32-5. Molecular formula: C19H32N2O5. Mole weight: 368.47.
BW 246C
The prostaglandin D2 (PGD2) receptors are the members of G protein-coupled receptors. PGD2 receptors include the following proteins prostaglandin D2 receptor 1 (DP1) and prostaglandin D2 receptor 2 (DP2). BW 246C is a DP receptor agonist. BW 246C is the less active C-8 diastereomer of the DP receptor agonist BW 245C. The activity of BW 245C is 70-fold greater than that of BW 246C. Synonyms: 8-epi BW 245C. Grade: ≥98%. CAS No. 65705-83-1. Molecular formula: C19H32N2O5. Mole weight: 368.5.
BW 373U86
BW 373U86 is a potent and selective non-peptide δ-opioid receptor agonist (Ki = 1.8, 15 and 34 nM for δ, μ and κ receptors, respectively). Synonyms: BW-373U86; SNC-86; BW 373U86; SNC 86; BW373U86; SNC86; 4-[(αR)-α-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-hydroxybenzyl]-N,N-diethylbenzamide. Grade: ≥99% by HPLC. CAS No. 155836-50-3. Molecular formula: C27H37N3O2. Mole weight: 435.61.
BW-723C86 is an orally active and a selective 5-HT 2B receptor agonist. BW-723C86 exhibits anxiolytic-like actions. BW-723C86 also causes hyperphagia and reduced grooming in rats. BW-723C86 dilates pulmonary arteries and inhibits liquid meal-induced gastric accommodation [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 160521-72-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101369.
BW 723C86 hydrochloride
BW 723C86 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 160521-72-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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BW 723C86 hydrochloride
BW 723C86 hydrochloride is a selective 5-HT2B receptor agonist used for the treatment of certain CNS disorders, such as epilepsy, migraine and feeding disorders. Uses: The treatment of cns disorders as epilepsy, migraine and feeding disorders. Synonyms: BW723C86; BW-723-C-86; BW 723 C 86; BW-723C86; BW 723C86; α-methyl-5-(2-thienylmethoxy)-1H-indole-3-ethanamine hydrochloride. Grade: ≥99% by HPLC. CAS No. 160521-72-2. Molecular formula: C16H18N2OS.HCl. Mole weight: 322.85.
BW 755C
Constitutive cyclooxygenase (COX-1) is present in cells under physiological conditions, whereas COX-2 is induced by some cytokines, mitogens, and endotoxin in pathological conditions, such as inflammation. Since 5-lipoxygenase (5-LO) oxidizes arachidonic acid to 5-hydroperoxyeicosatetraenoic acid. BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways. It inhibits 5-LO with IC50s of 0.75 μM, COX-1 with IC50s of 0.65 μg/ml, and COX-2 with IC50s of 1.2 μg/ml. BW 755C may also inhibit other LO pathways in vivo. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: BW755C; BW-755C; 1H-Pyrazol-3-amine, 4,5-dihydro-1-[3-(trifluoromethyl)phenyl]-; 4,5-Dihydro-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-3-amine; 1-(3-Trifluoromethylphenyl)-4,5-dihydro-1H-pyrazol-3-amine; 3-Amino-1-[3-(trifluoromethyl)phenyl]-2-pyrazoline; 3-Amino-1-[3-(trifluoromethyl)phenyl]pyrazoline; 3-Amino-1-[m-(trifluoromethyl)phenyl]-2-pyrazoline; Compound BW 755C. Grade: ≥95%. CAS No. 66000-40-6. Molecular formula: C10H10F3N3. Mole weight: 229.20.
BWA-522 is an orally available small molecule protein-targeting chimera (PROTACs) with significant degradation effect on AR-FL and AR-V7. BWA-522 antagonizes the N-terminal domain (AR-NTD) of the androgen receptor (Androgen Receptor) and induces apoptosis in PC cells. BWA-522 inhibits tumor growth in LNCaP xenograft model studies (60 mg/kg, po; TGI=76%). The efficiencies of BWA-522 in degrading AR-V7 and AR-FL were 77.3% (1 ?M) and 72.0% (5 ?M) in VCaP and LNCaP cells, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3042820-12-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-149433.
BW-A78U
BW-A 78U is a PDE4 inhibitor with an IC50 of 3 μM. BW-A 78U fails to significantly inhibit arachidonate release. It is ineffective to inhibit the lipopolysaccharide (LPS)-induced TNF-α release. Synonyms: BW A78U. Grade: ≥98%. CAS No. 101155-02-6. Molecular formula: C13H12FN5. Mole weight: 257.27.
Prostaglandin D2 (PGD2) has been widely distributed in rat brain, spinal cord and pituitary and may act as a neuromodulator in the central nervous system. BW A868C is a novel, selective and potent competitive antagonist of PGD2. BW A868C antagonizes the prostaglandin D2 and BW 245C-induced activation of human platelet adenylate cyclase. BW A868C antagonizes the accumulation of cAMP in rabbit non-pigmented ciliary epithelial cells. However, it has virtually no effect on human TP, IP, EP1, EP2, and FP receptors. Synonyms: BWA-868C; BWA868C. Grade: ≥98%. CAS No. 118675-50-6. Molecular formula: C25H37N3O5. Mole weight: 459.6.
BW B70C is a potent and selective inhibitor of 5-lipoxygenase (5-LO). 5-LO is an enzyme that transforms essential fatty acids (EFAs) into leukotrienes and is activated by 5-lipoxygenase activating protein (FLAP). BW-B 70C had high potency and long duration in vivo and was considered as potential anti-asthma drug. It was reported that BW B70C blocks leukotriene C4 synthesis by alveolar macrophages, which decreases the migration for leukocyte to the airway lumen. BW B70C didn't affect vascular leucocyte margination and the blood levels of secreted phospholipase A2 and TNF-α. Synonyms: N-[3-[3-(-Fluorophenoxy)phenyl]-1-methyl-2-propenyl]-N-hydroxyurea. Grade: ≥98%. CAS No. 134470-38-5. Molecular formula: C17H17FN2O3. Mole weight: 316.33.
BW-B 70C
BW-B 70C. Group: Biochemicals. Grades: Purified. CAS No. 134470-38-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
BWX 46
BWX 46. Group: Biochemicals. Grades: Purified. CAS No. 172997-92-1. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
BWX 46 Acetate
BWX 46 Acetate is a potent, highly selective neuropeptide Y (NPY) receptor agonist with IC50 of 0.5 nM. Synonyms: ((Cys31,Nva34)-NPY (27-36))2 Acetate. Molecular formula: C118H190N36O30S2. Mole weight: 2657.12.
BX-320
BX-320 is an inhibitor of the serine/threonine kinase 3-phosphoinositide-dependent protein kinase 1 (PDK1; IC50 = 30 nM). BX-320 also induces apoptosis. Synonyms: BX320; N-(3-(4-(3-(3-amino-2,2-dimethyl-3-oxopropanamido)propylamino)-5-bromopyrimidin-2-ylamino)phenyl)pyrrolidine-1-carboxamide. CAS No. 702676-93-5. Molecular formula: C23H31BrN8O3. Mole weight: 547.45.
BX-320
BX-320 is a selective, ATP-competitive, orally acitive, and direct PDK1 inhibitor with an IC 50 of 30 nM in a direct kinase assay format. BX-320 also induces apoptosis. Anticancer effect [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 702676-93-5. Pack Sizes: 1 mg. Product ID: HY-10515.
BX341
BX341, also known as bifluranol, is a new fluorinated bibenzyl anti-androgen and one of a series of bibenzyls designed to present some of the hormonal properties of diethylstilboestrol (DES) but with a lower potential for toxicity. Synonyms: BX341; BX 341; BX-341; 2-fluoro-4-[3-(3-fluoro-4-hydroxyphenyl)pentan-2-yl]phenol; bifluranol; erythro-2,3-bis(3-fluor-4-hydroxyphenyl)pentan. CAS No. 34633-34-6. Molecular formula: C17H18F2O2. Mole weight: 292.32.
BX 430 is a selective P2X4 allosteric antagonist (IC50 = 0.54 μM) binding noncompetitively to extracellular allosteric site. It exhibits >10-fold selectivity for human P2X4 receptors over P2X1, P2X2, P2X3, P2X5 and P2X7 receptors. BX 430 is inactive at mouse and rat P2X4 receptors. Synonyms: BX430; BX-430; BX 430; N-[2,6-Dibromo-4-(1-methylethyl)phenyl]-N'-(3-pyridinyl)urea. Grade: ≥99% by HPLC. CAS No. 688309-70-8. Molecular formula: C15H15Br2N3O. Mole weight: 413.11.
BX471 (ZK-811752) is an orally active, potent and selective non-peptide CCR1 antagonist with a Ki of 1 nM, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZK-811752. CAS No. 217645-70-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-12080.
BX 471
BX 471 is a selective CCR1 antagonist. Synonyms: (R)-1-(5-chloro-2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-2-oxoethoxy)phenyl)urea; BX471; BX 471; BX-471; ZK811752; ZK 811752; ZK-811752. CAS No. 217645-70-0. Molecular formula: C21H24ClFN4O3. Mole weight: 434.89.
BX 471
BX 471. Group: Biochemicals. Grades: Purified. CAS No. 217645-70-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
BX-471
BX-471, also known as ZK-811752, is a potent, selective non-peptide CCR1 antagonist (Ki = 1 nM for human CCR1). BX-471 exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4. BX-471 was developed Berlex and its parent company, Schering AG. BX-471 is the lead in a series of non-peptide chemokine receptor 1 (CCR1) antagonists, for the potential treatment of autoimmune diseases, in particular multiple sclerosis (MS). In March 2000, BX-471 was undergoing phase I trials for the potential treatment of autoimmune diseases. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BX471; BX 471; BX-471; ZK811752; ZK 811752; ZK-811752. Product Category: Antagonists. Appearance: Solid powder. CAS No. 217645-70-0. Molecular formula: C21H24ClFN4O3. Mole weight: 434.89. Purity: >98%. IUPACName: (R)-1-(5-chloro-2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-2-oxoethoxy)phenyl)urea. Canonical SMILES: C[C@H]1N(C(COC2=CC=C(Cl)C=C2NC(N)=O)=O)CCN(CC3=CC=C(F)C=C3)C1. Product ID: ACM217645700. Alfa Chemistry ISO 9001:2015 Certified. Categories: Bx41 (New York City bus).
BX471 hydrochloride
BX471 hydrochloride is a potent, selective non-peptide CCR1 antagonist (Ki = 1 nM for human CCR1). Synonyms: BX-471 hydrochloride; BX 471 hydrochloride; (R)-1-(5-chloro-2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-2-oxoethoxy)phenyl)urea hydrochloride. CAS No. 288262-96-4. Molecular formula: C21H25Cl2FN4O3. Mole weight: 471.35.
An orally active, selective antagonist for chemokine receptor 1 (CCR-1) (Ki = 1-5nM). Has been used in studies related to intracellular calcium mobilization and migration of leukocytes mediated through CCR-1. Group: Biochemicals. Grades: Highly Purified. CAS No. 217645-70-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
BX 513
BX 513 is a selective CCR1 receptor antagonist and a full inverse agonist of the HCMV-encoding chemokine receptor US28. It inhibits MIP-1α-induced intracellular calcium mobilization. Synonyms: 1-Piperidinepentanenitrile, 4-(4-chlorophenyl)-4-hydroxy-α,α-diphenyl-; 4-(4-Chlorophenyl)-4-hydroxy-α,α-diphenyl-1-piperidinepentanenitrile; VUF 2274; 5-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidyl]-2,2-diphenyl-pentanenitrile; BX-513; BX513. Grade: ≥95%. CAS No. 193542-65-3. Molecular formula: C28H29ClN2O. Mole weight: 445.00.
BX 513 hydrochloride
BX 513 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1216540-18-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
BX-513 hydrochloride
BX 513 hydrochloride is a selective CCR1 receptor antagonist (Ki = 0.04, > 10, > 10 and > 10 nM for CCR1, CCR5, CXCR2 and CXCR4 receptors, respectively), and also acts as a US28 agonist. It inhibits MIP-1α-induced intracellular calcium mobilization (IC50 = 2.5 μM). Synonyms: BX 513 hydrochloride; 193542-65-3; 1216540-18-9; BX-513 HCl; BX513Hydrochloride; VUF 2274; BX-513; 5-[4-(4-CHLOROPHENYL)-4-HYDROXYPIPERIDIN-1-YL]-2,2-DIPHENYLPENTANENITRILE HYDROCHLORIDE; 5-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenylpentanenitrile; hydrochloride; BX-513 hydrochloride; 4-(4-CHLOROPHENYL)-4-HYDROXY-A,A-DIPHENYL-1-PIPERIDINEPENTANENITRILE HYDROCHLORIDE; BX 513 HCL; DTXSID30719335; BCP27909; AKOS024457285; AS-57268; VUF 2274; VUF2274; BX513 hydrochloride; BX-513 hydrochloride; 1-Piperidinepentanenitrile,4-(4-chlorophenyl)-4-hydroxy-a,a-diphenyl-,HCl; 5-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenylpentanenitrile--hydrogen chloride (1/1). Grade: ≥99% by HPLC. CAS No. 1216540-18-9. Molecular formula: C28H30Cl2N2O. Mole weight: 481.46.
BX-517
BX-517, also known as PDK1 inhibitor2, is a cell-permeable indolinone compound that acts as a potent, ATP site-targeting PDK1 inhibitor (IC50 = 6 nM). BX-517 also blocks activation of Akt in tumor cells with 10-fold more potent (IC50 = 0.1-1.0 μM) than its analogs tested at the highest dose tested (10 μM). Synonyms: (Z)-N-(3-(1-(1H-pyrrol-2-yl)ethylidene)-2-hydroxy-3H-indol-5-yl)carbamimidic acid; BX-517; BX 517; BX517; PDK1 inhibitor2. CAS No. 850717-64-5. Molecular formula: C15H14N4O2. Mole weight: 282.3.
BX795
BX795 is a potent and selective inhibitor of PDK1, with an IC50 of 6 nM. BX795 is also a potent and relatively specific inhibitor of TBK1 and IKK?, with an IC50 of 6 and 41 nM, respectively. BX795 blocks phosphorylation of S6K1, Akt, PKC?, and GSK3?, and has lower selectivity over PKA, PKC, c-Kit, GSK3? etc. BX795 modulates autophagy[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 702675-74-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10514.
BX 795. Group: Biochemicals. Grades: Purified. CAS No. 702675-74-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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BX-795
3-Phosphoinositide-dependent protein kinase 1 (PDK1) is a serine-threonine kinase that phosphorylates and activates a range of other kinases, including PKB, PKA, and certain isoforms of PKC. BX795 is a potent and specific PDK1 inhibitor with IC50 of 6 nM, which is 140- and 1600-fold more selective than PKA and PKC. It is also a potent and relatively specific inhibitor of TBK1 with IC50 of 6 nM and IKK? with IC50 of 41 nM. Synonyms: BX 795; BX795. Grade: ≥98%. CAS No. 702675-74-9. Molecular formula: C23H26IN7O2S. Mole weight: 591.47.
BX 795 hydrochloride
BX 795 is a potent and specific PDK1 inhibitor with IC50 of 6 nM, which is 140- and 1600-fold more selective than PKA and PKC. Synonyms: N-(3-(5-Iodo-4-(3-(thiophene-2-carboxamido)propylamino)pyrimidin-2-ylamino)phenyl)pyrrolidine-1-carboxamide hydrochloride. Grade: 98%. CAS No. 1472611-45-2. Molecular formula: C23H26IN7O2S.HCl. Mole weight: 627.93.
Bx-86. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BX-86;Pyridoxatin. Product Category: Heterocyclic Organic Compound. CAS No. 149196-98-5. Molecular formula: C15H21NO3. Mole weight: 263.33. Purity: 0.96. IUPACName: 3-[(1R,2S,4R,6S)-2-ethenyl-4,6-dimethylcyclohexyl]-1,4-dihydroxypyridin-2-one. Canonical SMILES: CC1CC(C(C(C1)C=C)C2=C(C=CN(C2=O)O)O)C. Product ID: ACM149196985. Alfa Chemistry ISO 9001:2015 Certified. Categories: (-)-Pyridoxatin, Bx6 (New York City bus).
BX912
BX-912 is a selective inhibitor of 3-Phosphoinositide-dependent Kinase-1 (PDK1) with IC50 of 12 nM; >10 fold selectivity over PKA, PKC, C-Kit, EGFR etc. Synonyms: BX912; BX 912; BX-912. Grade: 0.98. CAS No. 702674-56-4. Molecular formula: C20H23BrN8O. Mole weight: 471.363.
BX-912
BX-912 is a direct, selective, and ATP-competitive PDK1 inhibitor (IC50=26 nM). BX-912 blocks PDK1/Akt signaling in tumor cells and inhibits the anchorage-dependent growth of a variety of tumor cell lines in culture or induces apoptosis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 702674-56-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11005.
Transfection Reagent for BxPC3 Pancreatic Cancer Cells. Optimized transfection protocol provided for transfection of siRNA, DNA, mRNA, and microRNA. Transfection Reagents. Transfection Enhancer. Complex Condenser. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 6321.
Nevada, Texas, USA
Byakangelicin
Byakangelicin. Group: Biochemicals. Grades: Plant Grade. CAS No. 482-25-7. Pack Sizes: 20mg. Molecular Formula: C17H18O7, Molecular Weight: 334.32. US Biological Life Sciences.
Worldwide
Byakangelicin
Byakangelicin is an effective inhibitor of sex hormones and affects the catabolism of endogenous hormones. It directly affects the cytochrome P450 isoform (CY) P3A4 in human hepatocytes. It is an inhibitor of aldose reductase used in the treatment of diabetic cataracts. Byakangelicin is a natural coumarin compound found in Murraya koenigii, Triphasia trifoliata, and other organisms. Synonyms: 7H-Furo[3,2-g][1]benzopyran-7-one, 9-[(2R)-2,3-dihydroxy-3-methylbutoxy]-4-methoxy-; 7H-Furo[3,2-g][1]benzopyran-7-one, 9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxy-, (R)-; 9-[(2R)-2,3-Dihydroxy-3-methylbutoxy]-4-methoxy-7H-furo[3,2-g][1]benzopyran-7-one; Biacangelicin; (+)-Byakangelicin; 5-Methoxy-8-(2,3-dihydroxy-3-methylbutoxy)psoralene; Bjacangelicin; Bjakangelicin; Byankagelicine. Grade: >98%. CAS No. 482-25-7. Molecular formula: C17H18O7. Mole weight: 334.32.
Byakangelicol
Byakangelicol. Group: Biochemicals. CAS No. 26091-79-2. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
BYK 191023 dihydrochloride
BYK 191023 is a highly selective inducible nitric-oxide synthase (iNOS) inhibitor. BYK 191023 interacts with the catalytic center of the enzyme. BYK 191023 can be used to study the in vivo and in vitro effects mediated by iNOS [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1216722-25-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-107584.
BYK 191023 dihydrochloride
BYK 191023 dihydrochloride is a potent and selective inhibitor of inducible nitric oxide synthase (iNOS) (IC50 = 86, 17000, 162000 nM for iNOS, nNOS and eNOS, respectively) acting in a NADPH- and time-dependent manner. BYK 191023 decreases the nitrite levels in rats, and reverses pathological hypotension in the rodent endotoxin model. Synonyms: BYK191023 Dihydrochloride; BYK-191023 Dihydrochloride; BYK 191023 Dihydrochloride; BYK191023 2HCl; BYK-191023 2HCl; BYK 191023 2HCl; ; 2-[2-(4-Methoxy-2-pyridinyl)ethyl]-1H-imidazo[4,5-b]pyridine dihydrochloride. Grade: ≥99% by HPLC. CAS No. 1216722-25-6. Molecular formula: C14H14N4O.2HCl. Mole weight: 327.21.
BYK 191023 Dihydrochloride
BYK 191023 Dihydrochloride was used to study the compositions of pentosan polysulfate salts for oral administration and methods of use. Group: Biochemicals. Grades: Highly Purified. CAS No. 1216722-25-6. Pack Sizes: 1mg, 5mg. Molecular Formula: C14H14N4O; 2(HCl), Molecular Weight: 254.2923646. US Biological Life Sciences.
BYK 204165 is a potent and selective poly(ADP-ribose) polymerase (PARP)-1 inhibitor (pIC50 = 5.38 and 7.35 for PARP-2 and PARP-1, respectively). BYK 204165 is 100-fold more potent for PARP-1 than PARP-2. Synonyms: PARP Inhibitor XIV; BYK204165; BYK-204165; BYK 204165; RT-017290; RT017290; RT 017290. 4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione. Grade: ≥99% by HPLC. CAS No. 1104546-89-5. Molecular formula: C15H12N2O2. Mole weight: 252.27.
BYK 204165
BYK 204165. Group: Biochemicals. Grades: Purified. CAS No. 1104546-89-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
BYK 49187
BYK 49187 is a non-selective PARP inhibitor (pIC50 = 8.36 and 7.50 for cell-free recombinant PARP-1 and murine PARP-2, respectively). Synonyms: BYK 49187; BYK49187; BYK-49187; 4,5-Dihydro-2-[4-(4-methyl-1H-imidazol-4-yl)-1-piperidinyl]-6H-imidazo[4,5,1-ij]quinolin-6-one. Grade: ≥98% by HPLC. CAS No. 163120-31-8. Molecular formula: C19H21N5O. Mole weight: 335.4.
BYK 49187
BYK 49187. Group: Biochemicals. Grades: Purified. CAS No. 163120-31-8. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Byssochlamic acid
Byssochlamic acid is a mycotoxin produced by Byssochlamys fulva (Paecilomyces variotII) and Bys. nivea. CAS No. 743-51-1. Molecular formula: C18H20O6. Mole weight: 332.35.
Byssochlamysol
Byssochlamysol is a steroid antibiotic extracted from the mycelium of Byssochlamys nivea. It has the activity of inhibiting the growth of tumor cells MCF-7. Molecular formula: C32H50O7. Mole weight: 546.73.
Bz 423
Bz 423 has been found to be an ATP synthase inhibitor and could suppress disease in lupus-prone mice at some extent. Uses: Immunologic factors. Synonyms: Bz-423; Bz 423; Bz423; 7-Chloro-1,3-dihydro-5-(4-hydroxyphenyl)-1-methyl-3-(2-naphthalenylmethyl)-2H-1,4-benzodiazepin-2-one. Grade: ≥98% by HPLC. CAS No. 216691-95-1. Molecular formula: C27H21ClN2O2. Mole weight: 440.92.
Bz 423
Bz 423 is a pro-apoptotic 1,4-benzodiazepine with therapeutic properties in murine models of lupus demonstrating selectivity for autoreactive lymphocytes, and activates Bax and Bak. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BZ48. CAS No. 216691-95-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13108.