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| Product | Description | |
|---|---|---|
| Behenyl myristate | Behenyl myristate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Myristic acid behenyl ester. Product Category: Wax Esters. Appearance: Solid. CAS No. 42232-05-3. Molecular formula: C36H72O2. Mole weight: 536.96. Purity: 99%+. Product ID: ACM42232053. Alfa Chemistry ISO 9001:2015 Certified. Categories: docosyl tetradecanoate. |  |
| Behenyl Oleate | Behenyl Oleate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Oleic acid behenyl ester. Product Category: Wax Esters. Appearance: Liquid. CAS No. 127566-70-5. Molecular formula: C40H78O2. Mole weight: 591.05. Purity: 0.97. Canonical SMILES: CCCCCCCCCCCCCCCCCCCCCOC(=O)CCCCCCC\\\\C=C/CCCCCCCC. Product ID: ACM127566705-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| Behenyl palmitate | Behenyl palmitate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Hexadecanoic acid, docosyl ester. Product Category: Promotional Products. Appearance: Solid. CAS No. 42232-33-7. Molecular formula: C38H76O2. Mole weight: 565.01. Purity: 95+%. IUPACName: docosyl hexadecanoate. Product ID: ACM42232337-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| Behenyl Stearate | Behenyl Stearate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Stearic acid behenyl ester. Product Category: Heterocyclic Organic CompoundWax Esters. Appearance: Solid. CAS No. 22413-03-2. Molecular formula: C40H80O2. Mole weight: 593.06. Purity: 0.98. Canonical SMILES: CCCCCCCCCCCCCCCCCCCCCCOC(=O)CCCCCCCCCCCCCCCCC. Product ID: ACM22413032. Alfa Chemistry ISO 9001:2015 Certified. | |
| Beinaglutide | Beinaglutide is a recombinant human GLP-1 (rhGLP-1) approved as a novel drug for diabetes treatment. Beinaglutide also has promising effect on obesity. Synonyms: Benaglutide; Glucagon like peptide-i (7-36); BEM-014; H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-OH. CAS No. 123475-27-4. Molecular formula: C149H225N39O46. Mole weight: 3298.61. |  |
| Bekanamycin | Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic produced by Streptomyces kanamyceticus , against an array of Gram-positive and Gram-negative bacterial strain [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Kanamycin B. CAS No. 4696-76-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1174. |  |
| BeKm 1 | BeKm 1 is a potent and selective KV11.1 (hERG) channel blocker. CAS No. 524962-01-4. Molecular formula: C174H261N51O52S6. Mole weight: 4091.65. | |
| BeKm-1 | BeKm-1 is a HERG (human ether-a-go-go-related gene) blocking compound. BeKm-1 can be used for the research of heart disease [1]. Uses: Scientific research. Group: Peptides. CAS No. 524962-01-4. Pack Sizes: 100 μg; 500 μg; 1 mg; 5 mg. Product ID: HY-P1440. | |
| Belactosin A | Belactosin A is produced by the strain of Streptomyces sp. No antibacterial activity. A inhibits the IC50 of HeLa S3 cells is 51μmol/L. Synonyms: (alphaS,1S)-alpha-(L-Alanylamino)-2beta-[[[(2R)-3alpha-[(S)-sec-butyl]-4-oxooxetane-2beta-yl]carbonyl]amino]cyclopropane-1beta-propionic acid. Molecular formula: C17H27N3O6. Mole weight: 369.41. | |
| Belactosin C | Belactosin C is produced by the strain of Streptomyces sp. No antibacterial activity. C inhibits the IC50 of HeLa S3 cells is 200μmol/L. Synonyms: SCHEMBL3448978; CHEMBL1783833. CAS No. 189871-55-4. Molecular formula: C16H27N3O6. Mole weight: 357.40. | |
| Belamcandol B | Belamcandol B. Group: Biochemicals. Alternative Names: 3-Methoxy-5-(10Z)-10-pentadecen-1-yl-phenol; (Z)-3-Methoxy-5-(10-pentadecenyl)phenol; 3-Methoxy-5-(10Z)-10-pentadecenylphenol. Grades: Highly Purified. CAS No. 137786-94-8. Pack Sizes: 5mg. Molecular Formula: C22H36O2, Molecular Weight: 332.52. US Biological Life Sciences. |  Worldwide |
| Belantamab | Belantamab is a humanized monoclonal antibody directed against the B-cell maturation antigen (BCMA). Belantamab can be used in the synthesis of Belantamab mafodotin, an ADC developed for the treatment of adult patients with relapsed or refractory multiple myeloma (RRMM). Synonyms: GSK2857914; GSK 2857914; GSK-2857914. CAS No. 2061894-48-0. | |
| Belantamab | Belantamab (GSK2857916) is a humanized IgG1 anti-BCMA/TNFRSF17 monoclonal antibody. Belantamab is linked to MMAF (HY-15579) through a non-cleavable ADC linker to synthesize the antibody-active molecule conjugate (ADC) Belantamab mafodotin (HY-P3239). After binding to BCMA on the surface of tumor cells, Belantamab mafodotin enters the cell through receptor-mediated endocytosis. After entering the cell, Belantamab mafodotin releases MMAF, blocks cell division by inhibiting tubulin polymerization, arrests the cell cycle and induces cell apoptosis. Belantamab can be used for the study of multiple myeloma, especially relapsed/refractory multiple myeloma [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: GSK2857914. CAS No. 2061894-48-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9980. | |
| Belantamab mafodotin | Belantamab mafodotin (GSK2857916) is composed of humanized and focused monoclonal antibody against B cell maturation antigen (BCMA) and McMMAF. Belantamab mafodotin has anti-myeloma activity [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: GSK2857916; Belantamab mafodotin-blm. CAS No. 2050232-20-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3239. | |
| Belapectin | Belapectin (GR-MD-02) is a Galectin-3 (Gal-3) inhibitor. Belapectin drives tumor-induced immunosuppression by inducing T cell Apoptosis. Belapectin promotes tumor regression and improves survival of tumor-bearing mice through a CD8+ T cell-dependent mechanism. Belapectin binds to Gal-3 with affinity K i of 2.8 μM [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GR-MD-02. CAS No. 1980787-47-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-114440. | |
| Belatacept | Belatacept is a soluble fusion protein that acts as a T-cell costimulation blocker. Synonyms: BMS 224818; BMS-224818; BMS224818; LEA 29Y. Grade: 95%. CAS No. 706808-37-9. | |
| Belatacept | Belatacept (BMS 224818) is a selective T-cell costimulation blocker and a costimulator of the CD28-CD80/86 pathway. Belatacept binds to the CD 80/86 ligand and inhibits CD-28-mediated T cell costimulation and IFN-γ production. Belatacept can be used in studies of immunosuppression in organ transplantation [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BMS 224818; LEA 29Y. CAS No. 706808-37-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-108813. | |
| Belcesiran | Belcesiran is an alpha-1-antitrypsin synthesis reducer. Synonyms: Dcr-a1at; all-P-ambo-2'-O-methyl-P-thioadenylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-deoxy-2'-fluoroadenylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-deoxy-2'-fluorouridylyl-(3'→5')-2'-deoxy-2'-fluorouridylyl-(3'→5')-2'-deoxy-2'-fluoroguanylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'- deoxy-2'-fluorocytidylyl-. CAS No. 2375562-54-0. Molecular formula: C666H877F15N231O417P57S6. Mole weight: 21033.47. | |
| Belimumab | Belimumab is a human monoclonal antibody that inhibits B lymphocyte stimulator (BLyS). Specific binding of belimumab with the soluble BLyS prevents the interaction of BLys with its three receptors and indirectly decreases the B-cell survival and production of autoantibodies. Belimumab has been approved for the treatment of systemic lupus erythematosus. Synonyms: Benlysta; LymphoStat B. CAS No. 356547-88-1. | |
| Belimumab | Belimumab (LymphoStat B) is a human IgG1λ monoclonal antibody that inhibits B-cell activating factor (BAFF). Belimumab can be used for systemic lupus erythematosus (SLE) research. Uses: Designed for use in research and industrial production. Additional or Alternative Names: belimumab. Product Category: Inhibitors. Appearance: Solid. CAS No. 356547-88-1. Mole weight: 0. Purity: 0.994. Product ID: ACM356547881. Alfa Chemistry ISO 9001:2015 Certified. | |
| Belimumab | Belimumab (LymphoStat B) is a humanized IgG1λ monoclonal antibody against B-lymphocyte stimulator ( BLyS ) protein. Belimumab antagonizes BLyS activity in autoimmune diseases and B-lymphocyte malignancies. Belimumab can be used for systemic lupus erythematosus (SLE) research [1] [2] [3] [4]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: LymphoStat B. CAS No. 356547-88-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P9952. | |
| Belinostat | Belinostat (PXD101; PX105684) is a potent HDAC inhibitor with an IC 50 of 27 nM in HeLa cell extracts. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PXD101; PX105684. CAS No. 866323-14-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10225. | |
| Belinostat | Belinostat. Group: Biochemicals. Alternative Names: N-Hydroxy-3- (3-phenylsulfamoylphenyl) acrylamide; PX 105684; PXD 101. Grades: Highly Purified. CAS No. 414864-00-9. Pack Sizes: 10mg. Molecular Formula: C15H14N2O4S, Molecular Weight: 318.35. US Biological Life Sciences. | Worldwide |
| Belinostat | Belinostat is a hydroxamic acid-type histone deacetylase (HDAC) inhibitor. Belinostat targets HDAC enzymes to inhibit tumor cell proliferation and angiogenesis, induce apoptosis and promote cellular differentiation. Uses: Antineoplastic agents. Synonyms: Belinostat; PXD 101; Beleodaq; PDX101; PX 105684; PXD-101; PXD101; (E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamide. CAS No. 414864-00-9. Molecular formula: C15H14N2O4S. Mole weight: 318.347. | |
| Belizatinib | Belizatinib is inhibitor of both anaplastic lymphoma kinase (ALK) and tropomyosin-related kinases (TRK). Belizatinib can bind to and inhibit both ALK and TRK kinases and this inhibition can lead to the disruption of ALK- and TRK-mediated signaling and impede tumor cell growth in ALK/TRK-overexpressing tumor cells. Phase I/II clinical trials for Lymphoma, Non-small cell lung cancer and Solid tumours is on-going. Uses: Lymphoma; non-small cell lung cancer; solid tumours. Synonyms: TSR011; TSR011; TSR 011; Belizatinib; 4-fluoro-N-(6-((4-(2-hydroxypropan-2-yl)piperidin-1-yl)methyl)-1-((1s,4s)-4-(isopropylcarbamoyl)cyclohexyl)-1H-benzo[d]imidazol-2-yl)benzamide. Grade: 98%. CAS No. 1357920-84-3. Molecular formula: C33H44FN5O3. Mole weight: 577.75. | |
| Belladonnae Extract | Belladonnae Extract. Applications: Treatment of smooth muscle spasm, and inhibition of glandular secretion, and treatment of gastric and duodenal ulcer disease, gastrointestinal spasms, kidney and biliary colic. stasis swelling, pain sida. Group: Others. Synonyms: Belladonnae Extract; Herba Belladonnae. Purity: 0.8%-1.5% Hyoscyamine. Appearance: Brown yellow fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Whole Herb. Species: Herba Belladonnae. Belladonnae Extract; Herba Belladonnae; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-159. |  |
| Belleau's Reagent | Belleau's Reagent. Group: Biochemicals. Alternative Names: 2,4-Bis(4-phenoxyphenyl)-1,3-dithia-2,4-diphosphetane 2,4-Disulfide. Grades: Highly Purified. CAS No. 88816-02-8. Pack Sizes: 2g, 5g, 10g, 25g, 50g. US Biological Life Sciences. | Worldwide |
| Bellidifolin | Bellidifolin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: bellidifolin;1,5,8-Trihydroxy-3-methoxy-9H-xanthen-9-one;1,5,8-Trihydroxy-3-methoxyxanthone;Bellidifoline;3-Methoxy-1,5,8-trihydroxyxanthen-9-one;9H-Xanthen-9-one, 1,5,8-trihydroxy-3-methoxy- (9ci);Bellidifolium;Brn 0288441. Product Category: Heterocyclic Organic Compound. CAS No. 2798-25-6. Molecular formula: C14H10O6. Mole weight: 274.23. Density: 1.586. Product ID: ACM2798256. Alfa Chemistry ISO 9001:2015 Certified. | |
| Bellidifolin | Bellidifolin. Group: Biochemicals. Alternative Names: 1,5,8-Trihydroxy-3-methoxyxanthone; Bellidifolium. Grades: Plant Grade. CAS No. 2798-25-6. Pack Sizes: 10mg. Molecular Formula: C14H10O6, Molecular Weight: 274.226. US Biological Life Sciences. | Worldwide |
| Bellidifolin | Bellidifolin is a xanthone that can be isolated from the plants of Gentiana species. Study shows that bellidifolin is a potent hypoglycemic agent in streptozotocin (STZ)-induced diabetic rats from Swertia japonica. Bellidifolin may contribute to the protective effects associated with nerve injury initiated by hypoxia by mechanisms related to inhibition of cell apoptosis independent of the ERK pathway, but may involve blockade of p38MAPK signaling pathway activation and downstream caspase-3 expression. Synonyms: 1,5,8-Trihydroxy-3-methoxy-9H-xanthen-9-one. Grade: 98.5%. CAS No. 2798-25-6. Molecular formula: C14H10O6. Mole weight: 274.228. | |
| Belnacasan | Belnacasan is a potent and selective inhibitor of caspase-1 with Ki of 0.8 nM. Belnacasan inhibits interlukin-1β biosynthesis. Synonyms: VX 765, VX765, VX-765, Belnacasan; (2S)-1-[(2S)-2-[(4-amino-3-chlorobenzoyl)amino]-3,3-dimethylbutanoyl]-N-[(2R,3S)-2-ethoxy-5-oxooxolan-3-yl]pyrrolidine-2-carboxamide. Grade: ≥98%. CAS No. 273404-37-8. Molecular formula: C24H33ClN4O6. Mole weight: 509. | |
| Belnacasan | Belnacasan (VX-765) is an orally bioactive proagent of VRT-043198, which is a potent and selective inhibitor of IL-converting enzyme (ICE)/caspase-1 with Kis of 0.8 nM and less than 0.6 nM for caspase-1 and caspase-4, respectively. Belnacasan (VX-765) inhibits the release of LPS-induced IL-1? and IL-18 by human PBMCs with an IC50 of ~0.7 ?M[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX-765. CAS No. 273404-37-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13205. | |
| Beloranib | Beloranib is an experimental drug candidate for the treatment of obesity. It was discovered by CKD Pharmaceuticals and is currently being developed by Zafgen. Beloranib, an analog of the natural chemical compound fumagillin, is an inhibitor of the enzyme METAP2. It was originally designed as angiogenesis inhibitor for the treatment of cancer. Uses: Angiogenesis inhibitors. Synonyms: 2-Propenoic acid, 3-[4-[2-(dimethylamino)ethoxy]phenyl]-, (3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-1-oxaspiro[2.5]oct-6-yl ester, (2E)-; CDK-732; CDK 732; CDK732; O-[4-(2-Dimethylaminoethoxy)-trans-cinnamoyl]fumagillol; 2-Propenoic acid, 3-[4-[2-(dimethylamino)ethoxy]phenyl]-, (3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-1-oxaspiro[2.5]oct-6-yl ester, (2E)-; ZGN 440. Grade: ≥95%. CAS No. 251111-30-5. Molecular formula: C29H41NO6. Mole weight: 499.64. | |
| Beloranib | Beloranib is a pharmaceutical drug that is currently being evaluated through biological studies for its potential to combat obesity. Group: Biochemicals. Grades: Highly Purified. CAS No. 251111-30-5. Pack Sizes: 250ug, 1mg. Molecular Formula: C29H41NO6. US Biological Life Sciences. | Worldwide |
| Beloranib | Beloranib is a fumagillin-class methionine aminopetidase-2 (MetAP2) inhibitor. Beloranib decreases food intake, body weight, fat mass, and the size of adipocytes [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZGN-440; CKD-732 free base. CAS No. 251111-30-5. Pack Sizes: 1 mg. Product ID: HY-14811. | |
| Beloranib Hemioxalate | Beloranib Hemioxalate is the acidic form of beloranib , which is an analog of the natural chemical compound fumagillin and is an experimental injectable drug candidate for the treatment of obesity. Synonyms: CKD 732; (2E)-(3R,4S,5S,6R)-5-Methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-1-oxaspiro[2.5]oct-6-yl Ester 3-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-propenoic Acid Ethanedioate (2:1). Grade: > 95%. CAS No. 529511-79-3. Molecular formula: C30H42NO8. Mole weight: 544.67. | |
| Belotecan | Belotecan (CKD-602 free base) is a DNA topoisomerase I inhibitor. Belotecan induces cell apoptosis and cell-cycle arrest. Belotecan is a camptothecin analogue with anti-tumor effects, it can be used for the research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CKD-602 free base. CAS No. 256411-32-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-13566. | |
| Belotecan | Belotecan binds to and inhibits the activity of topoisomerase I, stabilizing the cleavable complex of topoisomerase I-DNA, which inhibits the religation of single-stranded DNA breaks generated by topoisomerase I. Uses: Topoisomerase i inhibitors. Synonyms: Camtobell; CKD602; CKD 602; CKD-602; (4S)-4-Ethyl-4-hydroxy-11-(2-(isopropylamino)ethyl)-1,12-dihydro-14H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H)-dione. CAS No. 256411-32-2. Molecular formula: C25H27N3O4. Mole weight: 433.50. | |
| Belotecan hydrochloride | Belotecan hydrochloride (CKD-602 hydrochloride), a Topoisomerase I inhibitor, is a synthetic camptothecin derivative. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CKD-602. CAS No. 213819-48-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13566A. | |
| Belotecan hydrochloride | Belotecan hydrochloride is a topoisomerase I inhibitor. It is a synthetic and water-soluble camptothecin derivative which forms stable DNA-topoisomerase complexes during DNA replication and induces cell cycle arrest in the G2/M phase. CKD-602 has a significant effect on intracerebral glioma growth, with animals having significantly smaller tumors than those in the control group. Synonyms: 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-11-[2-[(1-methylethyl)amino]ethyl]-, hydrochloride (1:1), (4S)-; (S)-4-Ethyl-4-hydroxy-11-(2-(isopropylamino)ethyl)-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione hydrochloride; CKD 602; Belotecan monohydrochloride; (4S)-4-Ethyl-4-hydroxy-11-[2-[(1-methylethyl)amino]ethyl]-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione hydrochloride; 7-[2-(N-Isopropylamino)ethyl]-(20S)-camptothecin hydrochloride; Camtobell hydrochloride. Grade: ≥98% by HPLC. CAS No. 213819-48-8. Molecular formula: C25H27N3O4.HCl. Mole weight: 469.96. | |
| Beloxepin | Beloxepin is a dual norepinephrine reuptake inhibitor and serotonin receptor antagonist. Synonyms: ADL-6906; ADL 6906; ADL6906; ORG-4428; ORG4428; ORG 4428. Grade: 98% by HPLC. CAS No. 135928-30-2. Molecular formula: C19H21NO2. Mole weight: 295.4. | |
| Belrestotug | Belrestotug (EOS-448) is an antagonistic anti- TIGIT (VSIG9, VSTM3) human immunoglobulin G1 kappa (hIgG1 kappa) antibody. Belrestotug shows antineoplastic activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: EOS-448; EOS884448; GSK4428859A. CAS No. 2574438-65-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990032. | |
| Belumosudil | Belumosudil (KD025) is a selective inhibitor of ROCK2 with IC 50 s of 105 nM and 24 μM for ROCK2 and ROCK1, respectively. Anti-fibrotic properties [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KD025; SLx-2119. CAS No. 911417-87-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15307. | |
| Belumosudil mesylate | Belumosudil mesylate (KD025 mesylate) is a selective inhibitor of ROCK2 with IC 50 s of 105 nM and 24 μM for ROCK2 and ROCK1, respectively. Anti-fibrotic properties [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KD025 mesylate; SLx-2119 mesylate. CAS No. 2109704-99-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15307A. | |
| Belumosudil mesylate | Belumosudil is an orally bioavailable inhibitor of ROCK-II that is greater than 200-fold selective over ROCK-I (IC50s = 105 nM and 24 μM, respectively). Synonyms: KD025 mesylate; SLx-2119 mesylate; 2-(3-(4-(1H-indazol-5-ylamino)quinazolin-2-yl)phenoxy)-N-(propan-2-yl)acetamide methanesulfonate (1:1). CAS No. 2109704-99-4. Molecular formula: C27H28N6O5S. Mole weight: 548.62. | |
| Belvarafenib | Belvarafenib (HM95573) is a potent and pan RAF (Rapidly Accelerated Fibrosarcoma) inhibitor, with IC 50 s of 56 nM, 7 nM and 5 nM for B-RAF, B-RAF v600E and C-RAF respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HM95573; GDC-5573; RG6185. CAS No. 1446113-23-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-109080. | |
| Belvarafenib | Belvarafenib is a potent and selective pan-RAF kinase inhibitor with IC50 of 41 nM, 7 nM and 2 nM for BRAF WT, BRAF(V600E) and CRAF kinases, respectively. Synonyms: GDC5573; RG6185; HM95573. CAS No. 1446113-23-0. Molecular formula: C23H16ClFN6OS. Mole weight: 478.93. | |
| Belvarafenib TFA | Belvarafenib TFA is a potent and pan RAF (Rapidly Accelerated Fibrosarcoma) inhibitor. Synonyms: HM95573 TFA; GDC-5573 TFA; RG6185 TFA. Grade: ≥99%. Molecular formula: C25H17ClF4N6O3S. Mole weight: 592.95. | |
| Belzutifan | Belzutifan (PT2977) is an orally active and selective HIF-2α inhibitor with an IC 50 of 9 nM. Belzutifan, as a second-generation HIF-2α inhibitor, increases potency and improves pharmacokinetic profile. Belzutifan is a potential treatment for clear cell renal cell carcinoma (ccRCC) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PT2977; MK-6482. CAS No. 1672668-24-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125840. | |
| Belzutifan | Belzutifan. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(((1S,2S,3R)-2,3-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)-5-fluorobenzonitrile. CAS No. 1672668-24-4. Molecular formula: C17H12F3NO4S. Mole weight: 383.34. Catalog: APB1672668244. |  |
| Belzutifan Impurity 1 | Belzutifan Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(((1S,2S,3S)-2,3-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)-5-fluorobenzonitrile. CAS No. 1672668-51-7. Molecular formula: C17H12F3NO4S. Mole weight: 383.34. Catalog: APB1672668517. | |
| Belzutifan Impurity 4 | Belzutifan Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-fluoro-5-(((1S,2R,3R)-2-fluoro-1,3-dihydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)benzonitrile. CAS No. 1672668-57-3. Molecular formula: C17H13F2NO5S. Mole weight: 381.35. Catalog: APB1672668573. | |
| Bemarituzumab | Bemarituzumab is a first-in-class, humanized IgG1 monoclonal antibody against FGFR2b (a FGF receptor). Bemarituzumab blocks fibroblast growth factors from binding and activating FGFR2b. Bemarituzumab has the potential for cancer research [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1952272-74-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99010. | |
| Bemarituzumab | Bemarituzumab is a humanized monoclonal antibody that blocks FGFR2b. Bemarituzumab was approved for the treatment of tumors overexpressing FGFR2b. CAS No. 1952272-74-0. | |
| Bemcentinib | Bemcentinib Inhibitor. Uses: Scientific use. Product Category: T6269. CAS No. 1037624-75-1. |  |
| Bemcentinib | Bemcentinib is a selective small molecule inhibitor of Axl kinase, which showed activity to blocks tumor spread and prolongs survival in models of metastatic breast cancer. The receptor tyrosine kinase Axl may play an important role in cancer progression, invasion, metastasis, drug resistance, and patient mortality. R428 inhibits Axl with low nanomolar activity and blocked Axl-dependent events, including Akt phosphorylation, breast cancer cell invasion, and proinflammatory cytokine production. Pharmacologic investigations revealed favorable exposure after oral administration such that R428-treated tumors displayed a dose-dependent reduction in expression of the cytokine granulocyte macrophage colony-stimulating factor and the epithelial-mesenchymal transition transcriptional regulator Snail. In support of an earlier study, R428 inhibited angiogenesis in corneal micropocket and tumor models. R428 administration reduced metastatic burden and extended survival in MDA-MB-231 intracardiac and 4T1 orthotopic (median survival, >80 days compared with 52 days; P < 0.05) mouse models of breast cancer metastasis. Additionally, R428 synergized with cisplatin to enhance suppression of liver micrometastasis. Our results show that Axl signaling regulates breast cancer metastasis at multiple levels in tumor cells and tumor stromal cells and that selective Axl blockade confers therapeutic value in prolonging survival of animals bearing metast | |
| Bemcentinib | Bemcentinib (R428) is a potent and selective inhibitor of Axl with an IC 50 of 14 nM [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R428; BGB324. CAS No. 1037624-75-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15150. | |
| Bemegride | Bemegride (3-Ethyl-3-methylglutarimide) is a central nervous system stimulant and antidote for barbiturate poisoning [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 3-Ethyl-3-methylglutarimide; Bemegrid. CAS No. 64-65-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1326. | |
| Bemfivastatin hemicalcium | Bemfivastatin (PPD 10558) hemicalcium is an orally active lipid-lowering agent and HMG-CoA reductase inhibitor. Bemfivastatin hemicalcium enhances the activity of liver extracts. Bemfivastatin hemicalcium has no-observed adverse effect levels (NOAEL) with dosages of ≥320 mg/kg/d (rat developmental toxicity), ≥12.5 mg/kg/d (rabbit maternal toxicity), ≥25 mg/kg/d (rabbit developmental toxicity), respectively. Bemfivastatin hemicalcium can be used in the study of statin-related hypercholesterolemic myalgia in statin-intolerant patients. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PPD 10558 hemicalcium. CAS No. 805241-64-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106281A. | |
| Bemnifosbuvir | Bemnifosbuvir (AT-511) is a potent and orally active HCV viral replication inhibitor. Bemnifosbuvir is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro ( EC 90 =0.47 μM). Bemnifosbuvir has pangenotypic antiviral activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AT-511. CAS No. 1998705-64-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-137958A. | |
| Bemnifosbuvir | Bemnifosbuvir is the precursor drug form of the antiviral nucleoside analogue AT-9010. It reduces the infectious virus yield in cells infected with Middle East respiratory syndrome coronavirus (MERS-CoV), severe acute respiratory syndrome CoV (SARS-CoV), SARS-CoV-2, human CoV 229E (HCoV-229E), and HCoV-OC43 (EC90s = 37, 0.47, 2.8, 1.2, and 0.5 μM, respectively). Synonyms: propan-2-yl N-[(P5'S,2'R)-2-amino-2'-deoxy-2'-fluoro-N6,2'-dimethyl-OP-phenyl-5'-adenylyl]-L-alaninate; AT-511; N-[[P(S),2'R]-2-amino-2'-deoxy-2'-fluoro-N,2'-dimethyl-P-phenyl-5'-adenylyl]-L-alanine, 1-methylethyl ester. Grade: 98%. CAS No. 1998705-64-8. Molecular formula: C24H33FN7O7P. Mole weight: 581.53. | |
| Bemnifosbuvir hemisulfate | Bemnifosbuvir is the precursor drug form of the antiviral nucleoside analogue AT-9010. It reduces the infectious virus yield in cells infected with Middle East respiratory syndrome coronavirus (MERS-CoV), severe acute respiratory syndrome CoV (SARS-CoV), SARS-CoV-2, human CoV 229E (HCoV-229E), and HCoV-OC43 (EC90s = 37, 0.47, 2.8, 1.2, and 0.5 μM, respectively). Synonyms: RG-6422; RO 7496998; AT-527; AT 527; AT527. Grade: 99.33%. CAS No. 2241337-84-6. Molecular formula: C24H33FN7O7P.1/2H2O4S. Mole weight: 679.61. | |
| Bemotrizinol | Bemotrizinol. Group: Biochemicals. Alternative Names: CGF 1607; FAT 70'884; Tinosorb S; Tinosorb S Aqua; BEMT; 2,4-Bis[4-(2-ethylhexyloxy)-2-hydroxyphenyl]-6-(4-methoxyphenyl)-1,3,5-triazine; 2,2'-[6-(4-Methoxyphenyl)-1,3,5-triazine-2,4-diyl]bis[5-[(2-ethylhexyl)oxy]phenol. Grades: Highly Purified. CAS No. 187393-00-6. Pack Sizes: 25mg. Molecular Formula: C38H49N3O5, Molecular Weight: 627.809999999999. US Biological Life Sciences. | Worldwide |
| Bemotrizinol | Bemotrizinol (Tinosorb S), a compound that can absorb ultraviolet light, has been shown to accept atomic oxygen generated by N-oxide photodeoxygenation [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tinosorb S. CAS No. 187393-00-6. Pack Sizes: 1 g; 5 g. Product ID: HY-W099730. | |
| Bemotrizinol Impurity Mixture | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Bempedoic acid | Bempedoic acid (ETC-1002) is an ATP-citrate lyase (ACL) inhibitor [1]. Bempedoic acid (ETC-1002) activates AMPK [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ETC-1002; ESP-55016. CAS No. 738606-46-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12357. | |
| Bempedoic Acid Impurity 10 | Bempedoic Acid Impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1529323-27-0. Molecular formula: C9H18O3. Mole weight: 174.24. Catalog: APB1529323270. | |
| Bempedoic Acid Impurity 11 | Bempedoic Acid Impurity 11. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ethyl 7-bromo-2,2-dimethylheptanoate. CAS No. 123469-92-1. Molecular formula: C11H21BrO2. Mole weight: 265.19. Catalog: APB123469921. | |
| Bempikibart | Bempikibart (ADX-914) is a human anti-IL-7Rα antibody. Bempikibart can be used for the research of anti-inflammatory [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ADX-914. CAS No. 2622254-57-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990023. | |
| Benactyzine hydrochloride | Benactyzine hydrochloride is a competitive BChE inhibitor with a K i of 0.01 mM. Benactyzine hydrochloride is an anticholinergic drug. Benactyzine hydrochloride has the potential for organophosphate poisoning research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 57-37-4. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1542A. | |
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