A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the suppliers website for prices or more information.
| Product | Description | |
|---|---|---|
| Belinostat | Belinostat. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (E)-N-hydroxy-3-(3-(N-phenylsulfamoyl)phenyl)acrylamide. CAS No. 866323-14-0. Molecular Formula: C15H14N2O4S. Mole Weight: 318.35. Catalog: APB866323140. |  |
| Belinostat | Belinostat (PXD101; PX105684) is a potent HDAC inhibitor with an IC 50 of 27 nM in HeLa cell extracts. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PXD101; PX105684. CAS No. 866323-14-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10225. |  |
| Belinostat Acid | Belinostat Acid. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (E)-3-(3-(N-phenylsulfamoyl)phenyl)acrylic acid. CAS No. 866323-87-7. Molecular Formula: C15H13NO4S. Mole Weight: 303.33. Catalog: APB866323877. | |
| Belinostat Amide | Belinostat Amide. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (E)-3-(3-(N-phenylsulfamoyl)phenyl)acrylamide. CAS No. 1485081-57-9. Molecular Formula: C15H14N2O3S. Mole Weight: 302.35. Catalog: APB1485081579. | |
| Belinostat-d5 Glucuronide | Belinostat-d5 Glucuronide. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1486471-13-9 (non-labelled); (2S, 3S, 4S, 5R, 6S) -3, 4, 5-trihydroxy-6- ( ( (E) -3- (3- (N- (phenyl-d5) sulfamoyl) phenyl) acrylamido) oxy) tetrahydro-2H-pyran-2-carboxylic acid. Molecular Formula: C21H17D5N2O10S. Mole Weight: 499.5. Catalog: APB03494. | |
| Belinostat Glucuronide | Belinostat Glucuronide. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2S, 3S, 4S, 5R, 6S) -3, 4, 5-trihydroxy-6- ( ( (E) -3- (3- (N-phenylsulfamoyl) phenyl) acrylamido) oxy) tetrahydro-2H-pyran-2-carboxylic acid. CAS No. 1486471-13-9. Molecular Formula: C21H22N2O10S. Mole Weight: 494.47. Catalog: APB1486471139. | |
| Belinostat Impurity 1 | Belinostat Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Belinostat Impurity 1. Molecular Formula: C15H13NO4S. Mole Weight: 303.33. Catalog: APB03496. | |
| Belinostat Impurity A | Belinostat Impurity A. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-N-hydroxy-3-(3-(N-phenylsulfamoyl)phenyl)acrylamide. CAS No. 1884227-58-0. Molecular Formula: C15H14N2O4S. Mole Weight: 318.35. Catalog: APB1884227580. | |
| Belizatinib | Belizatinib is inhibitor of both anaplastic lymphoma kinase (ALK) and tropomyosin-related kinases (TRK). Belizatinib can bind to and inhibit both ALK and TRK kinases and this inhibition can lead to the disruption of ALK- and TRK-mediated signaling and impede tumor cell growth in ALK/TRK-overexpressing tumor cells. Phase I/II clinical trials for Lymphoma, Non-small cell lung cancer and Solid tumours is on-going. Uses: Lymphoma; non-small cell lung cancer; solid tumours. Synonyms: TSR011; TSR011; TSR 011; Belizatinib;4-fluoro-N-(6-((4-(2-hydroxypropan-2-yl)piperidin-1-yl)methyl)-1-((1s,4s)-4-(isopropylcarbamoyl)cyclohexyl)-1H-benzo[d]imidazol-2-yl)benzamide. Grades: 98%. CAS No. 1357920-84-3. Molecular formula: C33H44FN5O3. Mole weight: 577.75. |  |
| Belladonnae Extract | Belladonnae Extract. Applications: Treatment of smooth muscle spasm, and inhibition of glandular secretion, and treatment of gastric and duodenal ulcer disease, gastrointestinal spasms, kidney and biliary colic. stasis swelling, pain sida. Group: Others. Synonyms: Belladonnae Extract; Herba Belladonnae. Purity: 0.8%-1.5% Hyoscyamine. Appearance: Brown yellow fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Whole Herb. Species: Herba Belladonnae. Belladonnae Extract; Herba Belladonnae; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-159. |  |
| Belleau's Reagent | Belleau's Reagent. Group: Biochemicals. Alternative Names: 2,4-Bis(4-phenoxyphenyl)-1,3-dithia-2,4-diphosphetane 2,4-Disulfide. Grades: Highly Purified. CAS No. 88816-02-8. Pack Sizes: 2g, 5g, 10g, 25g, 50g. US Biological Life Sciences. |  Worldwide |
| Bellidifolin | Bellidifolin. Group: Biochemicals. Alternative Names: 1,5,8-Trihydroxy-3-methoxyxanthone; Bellidifolium. Grades: Plant Grade. CAS No. 2798-25-6. Pack Sizes: 10mg. Molecular Formula: C14H10O6, Molecular Weight: 274.226. US Biological Life Sciences. | Worldwide |
| Bellidifolin | Bellidifolin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: bellidifolin;1,5,8-Trihydroxy-3-methoxy-9H-xanthen-9-one;1,5,8-Trihydroxy-3-methoxyxanthone;Bellidifoline;3-Methoxy-1,5,8-trihydroxyxanthen-9-one;9H-Xanthen-9-one, 1,5,8-trihydroxy-3-methoxy- (9ci);Bellidifolium;Brn 0288441. Product Category: Heterocyclic Organic Compound. CAS No. 2798-25-6. Molecular formula: C14H10O6. Mole weight: 274.23. Density: 1.586. Product ID: ACM2798256. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Belnacasan | Belnacasan is a potent and selective inhibitor of caspase-1 with Ki of 0.8 nM. Belnacasan inhibits interlukin-1β biosynthesis. Synonyms: VX 765, VX765, VX-765, Belnacasan; (2S)-1-[(2S)-2-[(4-amino-3-chlorobenzoyl)amino]-3,3-dimethylbutanoyl]-N-[(2R,3S)-2-ethoxy-5-oxooxolan-3-yl]pyrrolidine-2-carboxamide. Grades: ≥98%. CAS No. 273404-37-8. Molecular formula: C24H33ClN4O6. Mole weight: 509. | |
| Beloranib | Beloranib is a pharmaceutical drug that is currently being evaluated through biological studies for its potential to combat obesity. Group: Biochemicals. Grades: Highly Purified. CAS No. 251111-30-5. Pack Sizes: 250ug, 1mg. Molecular Formula: C29H41NO6. US Biological Life Sciences. | Worldwide |
| Beloranib | Beloranib is a fumagillin-class methionine aminopetidase-2 (MetAP2) inhibitor. Beloranib decreases food intake, body weight, fat mass, and the size of adipocytes [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZGN-440; CKD-732 free base. CAS No. 251111-30-5. Pack Sizes: 1 mg. Product ID: HY-14811. | |
| Beloranib Hemioxalate | Beloranib Hemioxalate is the acidic form of beloranib , which is an analog of the natural chemical compound fumagillin and is an experimental injectable drug candidate for the treatment of obesity. Synonyms: CKD 732; (2E)-(3R,4S,5S,6R)-5-Methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-1-oxaspiro[2.5]oct-6-yl Ester 3-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-propenoic Acid Ethanedioate (2:1). Grades: > 95%. CAS No. 529511-79-3. Molecular formula: C30H42NO8. Mole weight: 544.67. | |
| Belotecan | Belotecan binds to and inhibits the activity of topoisomerase I, stabilizing the cleavable complex of topoisomerase I-DNA, which inhibits the religation of single-stranded DNA breaks generated by topoisomerase I. Uses: Topoisomerase i inhibitors. Synonyms: Camtobell; CKD602; CKD 602; CKD-602; (4S)-4-Ethyl-4-hydroxy-11-(2-(isopropylamino)ethyl)-1,12-dihydro-14H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H)-dione. CAS No. 256411-32-2. Molecular formula: C25H27N3O4. Mole weight: 433.50. | |
| Belotecan | Belotecan (CKD-602 free base) is a DNA topoisomerase I inhibitor. Belotecan induces cell apoptosis and cell-cycle arrest. Belotecan is a camptothecin analogue with anti-tumor effects, it can be used for the research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CKD-602 free base. CAS No. 256411-32-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-13566. | |
| Belotecan hydrochloride | Belotecan hydrochloride (CKD-602 hydrochloride), a Topoisomerase I inhibitor, is a synthetic camptothecin derivative. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CKD-602. CAS No. 213819-48-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13566A. | |
| Belrestotug | Belrestotug (EOS-448) is an antagonistic anti- TIGIT (VSIG9, VSTM3) human immunoglobulin G1 kappa (hIgG1 kappa) antibody. Belrestotug shows antineoplastic activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: EOS-448; EOS884448; GSK4428859A. CAS No. 2574438-65-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990032. | |
| Belumosudil | Belumosudil (KD025) is a selective inhibitor of ROCK2 with IC 50 s of 105 nM and 24 μM for ROCK2 and ROCK1, respectively. Anti-fibrotic properties [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KD025; SLx-2119. CAS No. 911417-87-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15307. | |
| Belumosudil Impurity 1 | Belumosudil Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(4-chloro-3-(4-chloroquinazolin-2-yl)phenoxy)-N-isopropylacetamide. Molecular Formula: C19H17Cl2N3O2. Mole Weight: 390.26. Catalog: APB03741. | |
| Belumosudil Impurity 10 | Belumosudil Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(3-(4-((1H-indazol-5-yl)amino)quinazolin-2-yl)phenoxy)acetic acid. CAS No. 911417-62-4. Molecular Formula: C23H17N5O3. Mole Weight: 411.41. Catalog: APB911417624. | |
| Belumosudil Impurity 11 | Belumosudil Impurity 11. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-isopropyl-2-(3-(4-((2-methyl-2H-indazol-5-yl)amino)quinazolin-2-yl)phenoxy)acetamide. Molecular Formula: C27H26N6O2. Mole Weight: 466.53. Catalog: APB03732. | |
| Belumosudil Impurity 12 | Belumosudil Impurity 12. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-isopropyl-2-(5-((2-(3-(2-(isopropylamino)-2-oxoethoxy)phenyl)quinazolin-4-yl)amino)-2H-indazol-2-yl)acetamide. Molecular Formula: C31H33N7O3. Mole Weight: 551.64. Catalog: APB03730. | |
| Belumosudil Impurity 13 | Belumosudil Impurity 13. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-isopropyl-2-(5-((2-(3-(2-(isopropylamino)-2-oxoethoxy)phenyl)quinazolin-4-yl)amino)-1H-indazol-1-yl)acetamide. Molecular Formula: C31H33N7O3. Mole Weight: 551.64. Catalog: APB03729. | |
| Belumosudil Impurity 14 | Belumosudil Impurity 14. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(3-acetoxyphenyl)quinazolin-4-yl acetate. Molecular Formula: C18H14N2O4. Mole Weight: 322.31. Catalog: APB03731. | |
| Belumosudil Impurity 15 | Belumosudil Impurity 15. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(4-oxo-3,4-dihydroquinazolin-2-yl)phenyl acetate. CAS No. 371947-93-2. Molecular Formula: C16H12N2O3. Mole Weight: 280.28. Catalog: APB371947932. | |
| Belumosudil Impurity 16 | Belumosudil Impurity 16. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: tert-butyl 5-amino-1H-indazole-1-carboxylate. CAS No. 129488-10-4. Molecular Formula: C12H15N3O2. Mole Weight: 233.27. Catalog: APB129488104. | |
| Belumosudil Impurity 17 | Belumosudil Impurity 17. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: tert-butyl 5-((2-(3-acetoxyphenyl)quinazolin-4-yl)amino)-1H-indazole-1-carboxylate. CAS No. 911417-25-9. Molecular Formula: C28H25N5O4. Mole Weight: 495.53. Catalog: APB911417259. | |
| Belumosudil Impurity 18 | Belumosudil Impurity 18. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: tert-butyl 5-((2-(3-hydroxyphenyl)quinazolin-4-yl)amino)-1H-indazole-1-carboxylate. CAS No. 911417-26-0. Molecular Formula: C26H23N5O3. Mole Weight: 453.49. Catalog: APB911417260. | |
| Belumosudil Impurity 19 | Belumosudil Impurity 19. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: tert-butyl 5-((2-(3-(2-(tert-butoxy)-2-oxoethoxy)phenyl)quinazolin-4-yl)amino)-1H-indazole-1-carboxylate. CAS No. 911417-61-3. Molecular Formula: C32H33N5O5. Mole Weight: 567.63. Catalog: APB911417613. | |
| Belumosudil Impurity 2 | Belumosudil Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(2-chloro-5-(4-chloroquinazolin-2-yl)phenoxy)-N-isopropylacetamide. Molecular Formula: C19H17Cl2N3O2. Mole Weight: 390.26. Catalog: APB03738. | |
| Belumosudil impurity 3 | Belumosudil impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 911417-87-3. Molecular Formula: C26H24N6O2. Mole Weight: 452.52. Catalog: APB911417873. | |
| Belumosudil Impurity 3 | Belumosudil Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-nitroso-1H-indazole. Molecular Formula: C7H5N3O. Mole Weight: 147.13. Catalog: APB03739. | |
| Belumosudil Impurity 4 | Belumosudil Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(1H-indazol-5-yl)hydroxylamine. Molecular Formula: C7H7N3O. Mole Weight: 149.15. Catalog: APB03740. | |
| Belumosudil Impurity 5 | Belumosudil Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1,2-di(1H-indazol-5-yl)diazene. Molecular Formula: C14H10N6. Mole Weight: 262.27. Catalog: APB03737. | |
| Belumosudil Impurity 6 | Belumosudil Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1,2-di(1H-indazol-5-yl)hydrazine. Molecular Formula: C14H12N6. Mole Weight: 264.29. Catalog: APB03736. | |
| Belumosudil Impurity 7 | Belumosudil Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1,2-di(1H-indazol-5-yl)diazene oxide. Molecular Formula: C14H10N6O. Mole Weight: 278.27. Catalog: APB03733. | |
| Belumosudil Impurity 8 | Belumosudil Impurity 8. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(2-carbamoylphenyl)-3-(2-((2-carbamoylphenyl)amino)-2-oxoethoxy)benzamide. Molecular Formula: C23H20N4O5. Mole Weight: 432.43. Catalog: APB03735. | |
| Belumosudil Impurity 9 | Belumosudil Impurity 9. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(4-((1H-indazol-5-yl)amino)quinazolin-2-yl)phenol. Molecular Formula: C21H15N5O. Mole Weight: 353.38. Catalog: APB03734. | |
| Belumosudil mesylate | Belumosudil mesylate (KD025 mesylate) is a selective inhibitor of ROCK2 with IC 50 s of 105 nM and 24 μM for ROCK2 and ROCK1, respectively. Anti-fibrotic properties [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KD025 mesylate; SLx-2119 mesylate. CAS No. 2109704-99-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15307A. | |
| Belumosudil Mesylate | Belumosudil Mesylate. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(3-(4-((1H-indazol-5-yl)amino)quinazolin-2-yl)phenoxy)-N-isopropylacetamide methanesulfonate. CAS No. 2109704-99-4. Molecular Formula: C26H24N6O2. Mole Weight: 452.51. Catalog: APB2109704994. | |
| Belvarafenib | Belvarafenib (HM95573) is a potent and pan RAF (Rapidly Accelerated Fibrosarcoma) inhibitor, with IC 50 s of 56 nM, 7 nM and 5 nM for B-RAF, B-RAF v600E and C-RAF respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HM95573; GDC-5573; RG6185. CAS No. 1446113-23-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-109080. | |
| Belzutifan | Belzutifan. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(((1S,2S,3R)-2,3-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)-5-fluorobenzonitrile. CAS No. 1672668-24-4. Molecular Formula: C17H12F3NO4S. Mole Weight: 383.34. Catalog: APB1672668244. | |
| Belzutifan | Belzutifan (PT2977) is an orally active and selective HIF-2α inhibitor with an IC 50 of 9 nM. Belzutifan, as a second-generation HIF-2α inhibitor, increases potency and improves pharmacokinetic profile. Belzutifan is a potential treatment for clear cell renal cell carcinoma (ccRCC) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PT2977; MK-6482. CAS No. 1672668-24-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125840. | |
| Belzutifan Impurity 1 | Belzutifan Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(((1S,2S,3S)-2,3-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)-5-fluorobenzonitrile. CAS No. 1672668-51-7. Molecular Formula: C17H12F3NO4S. Mole Weight: 383.34. Catalog: APB1672668517. | |
| Belzutifan Impurity 2 | Belzutifan Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(((1R,2R,3S)-2,3-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)-5-fluorobenzonitrile. CAS No. 2007088-15-3. Molecular Formula: C17H12F3NO4S. Mole Weight: 383.34. Catalog: APB2007088153. | |
| Belzutifan Impurity 3 | Belzutifan Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(((1R,2S,3R)-2,3-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)-5-fluorobenzonitrile. CAS No. 3004833-91-1. Molecular Formula: C17H12F3NO4S. Mole Weight: 383.34. Catalog: APB3004833911. | |
| Belzutifan Impurity 4 | Belzutifan Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-fluoro-5-(((1S,2R,3R)-2-fluoro-1,3-dihydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)benzonitrile. CAS No. 1672668-57-3. Molecular Formula: C17H13F2NO5S. Mole Weight: 381.35. Catalog: APB1672668573. | |
| Belzutifan Impurity 5 | Belzutifan Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(((1S,2S,3R)-3-(((1S,2R,3R)-4-(3-cyano-5-fluorophenoxy)-2-fluoro-3-(2-methoxyethoxy)-7-(methylsulfonyl)-2,3-dihydro-1H-inden-1-yl)oxy)-2-fluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)-5-fluorobenzonitrile. CAS No. 2738682-47-6. Molecular Formula: C37H30F4N2O10S2. Mole Weight: 802.77. Catalog: APB2738682476. | |
| Belzutifan Impurity 6 | Belzutifan Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(((1S,2S,3S)-1-(((1R,2S,3S)-7-(3-cyano-5-fluorophenoxy)-2-fluoro-3-hydroxy-4-(methylsulfonyl)-2,3-dihydro-1H-inden-1-yl)oxy)-2-fluoro-3-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)-5-fluorobenzonitrile. Molecular Formula: C34H24F4N2O9S2. Mole Weight: 744.69. Catalog: APB03721. | |
| Bemarituzumab | Bemarituzumab is a first-in-class, humanized IgG1 monoclonal antibody against FGFR2b (a FGF receptor). Bemarituzumab blocks fibroblast growth factors from binding and activating FGFR2b. Bemarituzumab has the potential for cancer research [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1952272-74-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99010. | |
| Bemarituzumab | Bemarituzumab is a humanized monoclonal antibody that blocks FGFR2b. Bemarituzumab was approved for the treatment of tumors overexpressing FGFR2b. CAS No. 1952272-74-0. | |
| Bemcentinib | Bemcentinib (R428) is a potent and selective inhibitor of Axl with an IC 50 of 14 nM [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R428; BGB324. CAS No. 1037624-75-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15150. | |
| Bemcentinib | Bemcentinib Inhibitor. Uses: Scientific use. Product Category: T6269. CAS No. 1037624-75-1. |  |
| Bemcentinib | Bemcentinib is a selective small molecule inhibitor of Axl kinase, which showed activity to blocks tumor spread and prolongs survival in models of metastatic breast cancer. The receptor tyrosine kinase Axl may play an important role in cancer progression, invasion, metastasis, drug resistance, and patient mortality. R428 inhibits Axl with low nanomolar activity and blocked Axl-dependent events, including Akt phosphorylation, breast cancer cell invasion, and proinflammatory cytokine production. Pharmacologic investigations revealed favorable exposure after oral administration such that R428-treated tumors displayed a dose-dependent reduction in expression of the cytokine granulocyte macrophage colony-stimulating factor and the epithelial-mesenchymal transition transcriptional regulator Snail. In support of an earlier study, R428 inhibited angiogenesis in corneal micropocket and tumor models. R428 administration reduced metastatic burden and extended survival in MDA-MB-231 intracardiac and 4T1 orthotopic (median survival, >80 days compared with 52 days; P < 0.05) mouse models of breast cancer metastasis. Additionally, R428 synergized with cisplatin to enhance suppression of liver micrometastasis. Our results show that Axl signaling regulates breast cancer metastasis at multiple levels in tumor cells and tumor stromal cells and that selective Axl blockade confers therapeutic value in prolonging survival of animals bearing metastatic tumors. Synonyms: BGB324; BGB-324; BGB 324; R 428; R-428; R428; 1-(6,7-dihydro-5H-benzo[2,3]cyclohepta[2,4-d]pyridazin-3-yl)-3-N-[(7S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-3-yl]-1,2,4-triazole-3,5-diamine. CAS No. 1037624-75-1. Molecular formula: C30H34N8. Mole weight: 506.658. | |
| Bemegride | Bemegride (3-Ethyl-3-methylglutarimide) is a central nervous system stimulant and antidote for barbiturate poisoning [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 3-Ethyl-3-methylglutarimide; Bemegrid. CAS No. 64-65-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1326. | |
| Bemegride | Bemegride is a central nervous system stimulant and antidote for barbiturate poisoning. Synonyms: Bemegride; Antibarbi; Agipnon; Ahypnon; Eukraton; Malysol; Mikedimide; Zentraleptin. Grades: >98%. CAS No. 64-65-3. Molecular formula: C8H13NO2. Mole weight: 155.19. | |
| Bemfivastatin hemicalcium | Bemfivastatin (PPD 10558) hemicalcium is an orally active lipid-lowering agent and HMG-CoA reductase inhibitor. Bemfivastatin hemicalcium enhances the activity of liver extracts. Bemfivastatin hemicalcium has no-observed adverse effect levels (NOAEL) with dosages of ≥320 mg/kg/d (rat developmental toxicity), ≥12.5 mg/kg/d (rabbit maternal toxicity), ≥25 mg/kg/d (rabbit developmental toxicity), respectively. Bemfivastatin hemicalcium can be used in the study of statin-related hypercholesterolemic myalgia in statin-intolerant patients. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PPD 10558 hemicalcium. CAS No. 805241-64-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106281A. | |
| Bemnifosbuvir | Bemnifosbuvir (AT-511) is a potent and orally active HCV viral replication inhibitor. Bemnifosbuvir is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro ( EC 90 =0.47 μM). Bemnifosbuvir has pangenotypic antiviral activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AT-511. CAS No. 1998705-64-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-137958A. | |
| Bemnifosbuvir | Bemnifosbuvir is the precursor drug form of the antiviral nucleoside analogue AT-9010. It reduces the infectious virus yield in cells infected with Middle East respiratory syndrome coronavirus (MERS-CoV), severe acute respiratory syndrome CoV (SARS-CoV), SARS-CoV-2, human CoV 229E (HCoV-229E), and HCoV-OC43 (EC90s = 37, 0.47, 2.8, 1.2, and 0.5 μM, respectively). Synonyms: propan-2-yl N-[(P5'S,2'R)-2-amino-2'-deoxy-2'-fluoro-N6,2'-dimethyl-OP-phenyl-5'-adenylyl]-L-alaninate; AT-511; N-[[P(S),2'R]-2-amino-2'-deoxy-2'-fluoro-N,2'-dimethyl-P-phenyl-5'-adenylyl]-L-alanine, 1-methylethyl ester. Grades: 98%. CAS No. 1998705-64-8. Molecular formula: C24H33FN7O7P. Mole weight: 581.53. | |
| Bemotrizinol | Bemotrizinol. Group: Biochemicals. Alternative Names: CGF 1607; FAT 70'884; Tinosorb S; Tinosorb S Aqua; BEMT; 2,4-Bis[4-(2-ethylhexyloxy)-2-hydroxyphenyl]-6-(4-methoxyphenyl)-1,3,5-triazine; 2,2'-[6-(4-Methoxyphenyl)-1,3,5-triazine-2,4-diyl]bis[5-[(2-ethylhexyl)oxy]phenol. Grades: Highly Purified. CAS No. 187393-00-6. Pack Sizes: 25mg. Molecular Formula: C38H49N3O5, Molecular Weight: 627.809999999999. US Biological Life Sciences. | Worldwide |
| Bemotrizinol | Bemotrizinol (Tinosorb S), a compound that can absorb ultraviolet light, has been shown to accept atomic oxygen generated by N-oxide photodeoxygenation [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tinosorb S. CAS No. 187393-00-6. Pack Sizes: 1 g; 5 g. Product ID: HY-W099730. | |
| Bempedoic acid | Bempedoic acid (ETC-1002) is an ATP-citrate lyase (ACL) inhibitor [1]. Bempedoic acid (ETC-1002) activates AMPK [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ETC-1002; ESP-55016. CAS No. 738606-46-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12357. | |
| Bempedoic Acid | Bempedoic Acid. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid. CAS No. 738606-46-7. Molecular Formula: C19H36O5. Mole Weight: 344.49. Catalog: APB738606467. | |
| Bempedoic Acid Impurity 1 | Bempedoic Acid Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2,2,14,14-tetramethyl-8-oxopentadecanedioic acid. CAS No. 413624-71-2. Molecular Formula: C19H34O5. Mole Weight: 342.47. Catalog: APB413624712. | |
| Bempedoic Acid Impurity 10 | Bempedoic Acid Impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1529323-27-0. Molecular Formula: C9H18O3. Mole Weight: 174.24. Catalog: APB1529323270. | |
| Bempedoic Acid Impurity 10 | Bempedoic Acid Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-cyano-8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid. Molecular Formula: C20H35NO5. Mole Weight: 369.50. Catalog: APB03724. | |
Our database is helping our users find suppliers everyday.
