A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Bimatoprost Impurity 13. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-N-ethyl-7-((1R,2R,3R,5S)-2-((E)-3-oxo-5-phenylpent-1-en-1-yl)-3,5-bis((tetrahydro-2H-pyran-2-yl)oxy)cyclopentyl)hept-5-enamide. Molecular Formula: C35H51NO6. Mole Weight: 581.78. Catalog: APB03906.
Bimatoprost Impurity 14
Bimatoprost Impurity 14 is one of bimatoprost impurities. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Molecular formula: C35H53NO6. Mole weight: 583.80.
Bimatoprost Impurity 14
Bimatoprost Impurity 14. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-N-ethyl-7-((1R,2R,3R,5S)-2-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)-3,5-bis((tetrahydro-2H-pyran-2-yl)oxy)cyclopentyl)hept-5-enamide. Molecular Formula: C35H53NO6. Mole Weight: 583.80. Catalog: APB03905.
Bimatoprost Impurity 15
Bimatoprost Impurity 15. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3aR,4R,5R,6aS)-4-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-2,5-diol. CAS No. 856240-62-5. Molecular Formula: C18H24O4. Mole Weight: 304.38. Catalog: APB856240625.
Bimatoprost Impurity 16
Bimatoprost Impurity 16. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (1S,3R,4R,5R)-4-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)-5-(2-hydroxyethyl)cyclopentane-1,3-diol. Molecular Formula: C18H26O4. Mole Weight: 306.40. Catalog: APB03904.
Bimatoprost Impurity 17
Bimatoprost Impurity 17. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-ethyl 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl)hept-5-enoate. Molecular Formula: C25H36O5. Mole Weight: 416.55. Catalog: APB03903.
Bimatoprost Impurity 18
Bimatoprost Impurity 18. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3aR,4R,5R,6aS)-5-hydroxy-4-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-2-one. CAS No. 41639-74-1. Molecular Formula: C18H22O4. Mole Weight: 302.36. Catalog: APB41639741.
Bimatoprost Impurity 19
Bimatoprost Impurity 19. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R)-3-hydroxy-5-phenylpentyl)cyclopentyl)-N-ethylhept-5-enamide. CAS No. 607351-44-0. Molecular Formula: C25H39NO4. Mole Weight: 417.58. Catalog: APB607351440.
Bimatoprost Impurity 20
Bimatoprost Impurity 20. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-(diphenylphosphoryl)-N-ethylpentanamide. CAS No. 2512198-63-7. Molecular Formula: C19H24NO2P. Mole Weight: 329.37. Catalog: APB2512198637.
Bimatoprost Impurity 22
Bimatoprost Impurity 22. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-N1,N10-diethyldec-5-enediamide. Molecular Formula: C14H26N2O2. Mole Weight: 254.37. Catalog: APB03902.
Bimatoprost Impurity 26
Bimatoprost Impurity 26. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (E)-N1,N10-diethyldec-5-enediamide. Molecular Formula: C14H26N2O2. Mole Weight: 254.37. Catalog: APB03897.
Bimatoprost Impurity 27
Bimatoprost Impurity 27. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (E)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-(3-hydroxy-5-phenylpentyl)cyclopentyl)hept-5-enoic acid. Molecular Formula: C23H34O5. Mole Weight: 390.51. Catalog: APB03899.
Bimatoprost Impurity 28
Bimatoprost Impurity 28. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3aR,4R,5R,6aS)-2-hydroxy-4-((R)-3-hydroxy-5-phenylpentyl)hexahydro-2H-cyclopenta[b]furan-5-yl [1,1'-biphenyl]-4-carboxylate. Molecular Formula: C31H34O5. Mole Weight: 486.60. Catalog: APB03898.
Bimatoprost Impurity 3
Bimatoprost Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((2S)-3-((S)-1-hydroxy-3-phenylpropyl)oxiran-2-yl)cyclopentyl)-N-ethylhept-5-enamide. Molecular Formula: C25H37NO5. Mole Weight: 431.56. Catalog: APB03911.
Bimatoprost Impurity 3
Bimatoprost Impurity 3 is one of bimatoprost impurities. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Molecular formula: C23H33NO4. Mole weight: 387.51.
Bimatoprost Impurity 31
Bimatoprost Impurity 31. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-N-cyclohexyl-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl)hept-5-enamide. Molecular Formula: C29H43NO4. Mole Weight: 469.66. Catalog: APB03896.
Bimatoprost Impurity 32
Bimatoprost Impurity 32. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl)-N,N-diethylhept-5-enamide. Molecular Formula: C27H41NO4. Mole Weight: 443.62. Catalog: APB03895.
Bimatoprost Impurity 33
Bimatoprost Impurity 33. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (1E,3S,9Z,11aR,12S,14R,14aR)-12,14-dihydroxy-3-phenethyl-7,8,11,11a,12,13,14,14a-octahydro-3H-cyclopenta[e][1]oxacyclotridecin-5(6H)-one. Molecular Formula: C23H30O4. Mole Weight: 370.48. Catalog: APB03717.
Bimatoprost Impurity 4
Bimatoprost Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl)hept-5-enamide. Molecular Formula: C23H33NO4. Mole Weight: 387.51. Catalog: APB03910.
Bimatoprost Impurity 5
Bimatoprost Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C25H37NO5. Mole Weight: 431.57. Catalog: APB11643.
Bimatoprost Impurity 5
Bimatoprost Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl)-N-methylhept-5-enamide. CAS No. 155206-01-2. Molecular Formula: C24H35NO4. Mole Weight: 401.54. Catalog: APB155206012.
Bimatoprost Impurity 6
Bimatoprost Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R,E)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl)hept-5-enoic acid. CAS No. 41639-71-8. Molecular Formula: C23H32O5. Mole Weight: 388.50. Catalog: APB41639718.
Bimatoprost Impurity 8
Bimatoprost Impurity 8. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3aS,4R,5S,6aR)-5-hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopenta[b]furan-2-one. CAS No. 76704-05-7. Molecular Formula: C8H12O4. Mole Weight: 172.18. Catalog: APB76704057.
Bimatoprost Impurity 9 is one of bimatoprost impurities. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Molecular formula: C34H63NO6Si. Mole weight: 609.95.
Bim BH3
Bim BH3 is a biological active peptide. (This Bim peptide belongs to the pro-apoptotic Bcl-2 family of proteins.). Uses: Scientific research. Group: Peptides. CAS No. 505070-06-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P1527.
BIM (Biotin)
BIM (Biotin). Group: Biochemicals. Grades: Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Bimekizumab
Bimekizumab (Anti-Human IL17A/IL-17F Recombinant Antibody) is a humanised monoclonal antibody, can selectively neutralises IL-17A and IL-17F. Both of them are pro-osteogenic with respect to human periosteum-derived cell (hPDC) differentiation. Thus Bimekizumab blocks the inflammation-driven osteogenic differentiation [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human IL17A/IL-17F Recombinant Antibody. CAS No. 1418205-77-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99280.
Bimiralisib free base
Bimiralisib, also known as PQR309, is an orally bioavailable pan inhibitor of phosphoinositide-3-kinases (PI3K) and inhibitor of the mammalian target of rapamycin (mTOR), with potential antineoplastic activity. PI3K/mTOR kinase inhibitor PQR309 inhibits the PI3K kinase isoforms alpha, beta, gamma and delta and, to a lesser extent, mTOR kinase, which may result in tumor cell apoptosis and growth inhibition in cells overexpressing PI3K/mTOR. Activation of the PI3K/mTOR pathway promotes cell growth, survival, and resistance to both chemotherapy and radiotherapy. Group: Inhibitors. Alternative Names: PQR309; PQR-309; PQR309; Bimiralisib free base. CAS No. 1225037-39-7. Molecular formula: C17H20F3N7O2. Mole weight: 411.39. Appearance: Solid powder. Purity: >98%. IUPACName: 5-(4,6-dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine. Canonical SMILES: NC1=NC=C (C2=NC (N3CCOCC3)=NC (N4CCOCC4)=N2)C (C (F) (F)F)=C1. Catalog: ACM1225037397.
Bimoclomol
Bimoclomol is a heat shock protein (HSP) coinducer, used for treatment of cardiovascular diseases. Uses: Scientific research. Group: Signaling pathways. CAS No. 130493-03-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00398.
Bimoclomol
Bimoclomol is a heat shock protein (HSP) coinducer that exhibits cytoprotective effects. It can be used in the treatment of cardiovascular diseases. Synonyms: (3Z)-N-(2-hydroxy-3-piperidin-1-ylpropoxy)pyridine-3-carboximidoyl chloride; bimoclomol; bimoclomol, maleate (1:1). CAS No. 130493-03-7. Molecular formula: C14H20ClN3O2. Mole weight: 297.78.
Bimolane
Bimolane (AT-1727), a human topoisomerase II inhibitor, can be used as an anti-neoplastic agent and for the research of psoriasis. Bimolane shows leukemogenic activity and induces multiple types of chromosomal aberrations in human lymphocytes. Group: Inhibitors. Alternative Names: Bimolane;4, 4'-Ethylenebis[1-(morpholinomethyl)-2, 6-piperazinedione];AT-1727. CAS No. 74550-97-3. Molecular formula: C20H32N6O6. Catalog: ACM74550973.
Bimolane
Bimolane is a topoisomerase II inhibitor. It has been widely used as an anti-neoplastic agent and for the treatment of psoriasis in China. Bimolane is also a leukemogenic agent and is thought to exert its effects through the inhibition of topoisomerase II. Uses: Psoriasis. Synonyms: Bimolane;4,4'-Ethylenebis[1-(morpholinomethyl)-2,6-piperazinedione];AT-1727; AT1727; AT 1727; CCRIS 7574; CCRIS7574; CCRIS-7574; NSC 351358. Grades: 98%. CAS No. 74550-97-3. Molecular formula: C20H32N6O6. Mole weight: 452.51.
BIMU 8
BIMU 8 is a potent and selective 5-HT4 agonist with EC 50 s of 18 nM, 77 nM, and 540 nM for wild type 5HT4 receptor , T3.36A , and W6.48A mutant 5-HT4 receptors [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 134296-40-5. Pack Sizes: 1 mg. Product ID: HY-110094.
BIMU 8
BIMU 8 is a potent and selective 5-HT4 receptor full agonist (KD = 77 nM and EC50 = 18 nM for wild type 5-HT4 receptors). Synonyms: BIMU 8; BIMU8; BIMU-8; 2,3-Dihydro-N-[(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]-3-(1-methylethyl)-2-oxo-1H-benzimidazole-1-carboxamide hydrochloride; N-[(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-3-propan-2-ylbenzimidazole-1-carboxamide hydrochloride. Grades: ≥98% by HPLC. CAS No. 134296-40-5. Molecular formula: C19H26N4O2.HCl. Mole weight: 378.9.
BIMU 8
BIMU 8. Group: Biochemicals. Grades: Purified. CAS No. 134296-40-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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BIN1b
Bin1b is a beta-defensins-like molecule originally isolated from the rat epididymis.
BINA
BINA is a selective positive allosteric modulator of mGlu2 (EC50 = 33.2 nM in CHO cells expressing human mGlu2) with no effect on glutamate-induced activation of other mGlu receptor subtypes. BINA exhibits antipsychotic and anxiolytic properties in mice. Synonyms: 3'-[[(2-Cyclopentyl-2,3-dihydro-6,7-dimethyl-1-oxo-1H-inden-5-yl)oxy]methyl]-[1,1'-biphenyl]-4-carboxylic acid; Biphenylindanone A; Biphenyl-indanone A. Grades: ≥98% by HPLC. CAS No. 866823-73-6. Molecular formula: C30H30O4. Mole weight: 454.56.
BINA
BINA. Group: Biochemicals. Grades: Purified. CAS No. 866823-73-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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BINA (Biphenyl-indanone A)
A selective positive allosteric modulator for mGlu receptor subtype 2 (EC50 = 33.2nM in CHO cells expressing human mGlu2). No effect on other mGlu receptor subtypes. Exhibits antipsychotic and anxiolytic properties in mice. Group: Biochemicals. Grades: Highly Purified. CAS No. 866823-73-6. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
BINAP, mono-oxide
BINAP, mono-oxide (CAS# 204862-91-9 ) is a useful research chemical. Grades: 95 %. CAS No. 204862-91-9. Molecular formula: C44H32OP2. Mole weight: 638.69.
Bindarit treatment inhibits the release of MCP-1 from IL-1 stimulated osteoblast cell line Saos-2. Synonyms: Bindarit; AF-2838; AF2838; AF 2838. Grades: >98%. CAS No. 130641-38-2. Molecular formula: C19H20N2O3. Mole weight: 324.37.
Bindarit
Bindarit shows anti-inflammatory activity due to a selective inhibition of a subfamily of inflammatory chemokines. Bindarit is a also protein antidenaturant agent. Bindarit modulates the NFkB pathway and has been shown to reduce secondary phase of adjuvant arthritis in rats. Group: Biochemicals. Alternative Names: 2-Methyl-2-[[1-(phenylmethyl)-1H-indazol-3-yl]methoxy]propanoic Acid; 2-[(1-Benzyl-1H-indazol-3-yl)methoxy]-2-methylpropanoic Acid; 2-[(1-Benzyl-1H-indazol-3-yl)methoxy]-2-methylpropionic Acid; AF 2838. Grades: Highly Purified. CAS No. 130641-38-2. Pack Sizes: 5mg. US Biological Life Sciences.
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Bindarit-d5
Bindarit-d5. Group: Biochemicals. Alternative Names: 2-Methyl-2-[[1-(phenylmethyl)-1H-indazol-3-yl]methoxy]propanoic Acid-d5; 2-[(1-Benzyl-1H-indazol-3-yl)methoxy]-2-methylpropanoic Acid-d5; 2-[(1-Benzyl-1H-indazol-3-yl)methoxy]-2-methylpropionic Acid-d5; AF 2838-d5. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C19H15D5N2O3, Molecular Weight: 329.4. US Biological Life Sciences.
Binodenoson is a pharmacologic stress agent specific to the only adenosine receptor necessary for increased cardiac blood flow, the A2A receptor agonist. It is used to diagnose coronary artery disease. Uses: Purinergic p1 receptor agonists. Synonyms: 2- (Cyclohexylmethylidenehydrazino) adenosine; 2-(2-(Cyclohexylmethylene)diazanyl)-9-beta-D-ribofuranosyl-9H-purin-6-amine; (2R,3R,4S,5R)-2-(6-Amino-2-(2-(cyclohexylmethylene)hydrazinyl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. Grades: ≥95%. CAS No. 144348-08-3. Molecular formula: C17H25N7O4. Mole weight: 391.42.
Bintrafusp alfa
Bintrafusp alfa (M 7824) is a first-in-class bifunctional fusion protein composed of the extracellular domain of TGF-βRII fused to a human IgG1 mAb blocking programmed cell death ligand. Bintrafusp alfa can be used for the research of cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: M7824; MSB0011359C. CAS No. 1918149-01-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99480.
Binucleine 2
Binucleine 2 is an inhibitor of cytokinesis function of the ARK-2 pathway. It is also an isoform-specific and ATP-competitive inhibitor of Drosophila Aurora B kinase (Ki = 0.36 μM), a kinase involved in cell division. It is specific for Drosophila Aurora B kinase, inhibiting it in a dose-dependent manner, with minimal inhibition of human or X. laevis Aurora B kinases at concentrations up to 100 μM. Binucleine 2 induces mitotic and cytokinesis defects in Drosophila Kc167 cells. Synonyms: Binucleine 2; 220088-42-6; N'-[2-(3-chloro-4-fluorophenyl)-4-cyanopyrazol-3-yl]-N,N-dimethylmethanimidamide; N'-(1-(3-Chloro-4-fluorophenyl)-4-cyano-1H-pyrazol-5-yl)-N,N-dimethyliminoformamide; HMS546I06; Probes1_000319; Probes2_000073; CHEMBL1598812; DTXSID90430554; Binucleine 2, >=97% (HPLC); CCG-41865; MFCD00177827; AKOS040755467; NCGC00165742-01; J-014418; SR-01000631912-1; N'-(1-(3-Chloro-4-fluorophenyl)-4-cyano-1H-pyrazol-5-yl)-N,N-dimethylformimidamide. Grades: ≥98%. CAS No. 220088-42-6. Molecular formula: C13H11ClFN5. Mole weight: 291.7.
BIO
BIO. Group: Biochemicals. Grades: Purified. CAS No. 667463-62-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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BIO
BIO is a potent and reversible inhibitor of GSK-3 with IC50 of 5 nM for GSK-3α/&beta. BIO enhances reprogramming of mouse fibroblasts, neural stem cells, and thymocytes to induced pluripotent stem (iPS) cells. It also promotes differentiation of cardiomyocytes from human ES and iPS cells. Synonyms: GSK-3 Inhibitor IX; 6-bromoindirubin-3-oxime; 6-bromo-3-(3-nitroso-1H-indol-2-yl)-1H-indol-2-ol. Grades: >98%. CAS No. 667463-62-9. Molecular formula: C16H10BrN3O2. Mole weight: 356.17.
BIO-11006
BIO-11006 is a myristoylated alanine-rich C kinase substrate (MARCKS) inhibitor, similar to MANS peptides. Synonyms: BIO-11006 peptide; L-Lysine, N-acetylglycyl-L-alanyl-L-glutaminyl-L-phenylalanyl-L-seryl-L-lysyl-L-threonyl-L-alanyl-L-alanyl-; N-Acetylglycyl-L-alanyl-L-glutaminyl-L-phenylalanyl-L-seryl-L-lysyl-L-threonyl-L-alanyl-L-alanyl-L-lysine; BIO 11006; BIO11006; Ac-Gly-Ala-Gln-Phe-Ser-Lys-Thr-Ala-Ala-Lys-OH. Grades: ≥95%. CAS No. 901117-03-1. Molecular formula: C46H75N13O15. Mole weight: 1050.17.
BIO 1211
BIO 1211. Group: Biochemicals. Grades: Purified. CAS No. 187735-94-0. Pack Sizes: 1mg. US Biological Life Sciences.
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BIO 1211
BIO 1211 is a selective and high affinity integrin α4β1 (Very Late Antigen 4; VLA-4) inhibitor with 200-fold selectivity for the activated form of α4β1 (KD = 70 pM; IC50=0.004 μM). Synonyms: BIO-1211; BIO1211. Grades: >98%. CAS No. 187735-94-0. Molecular formula: C36H48N6O9. Mole weight: 708.8.
BIO (2Z, 3E)-6-Bromo-3-(hydroxyimino)-[2,3-biindolinylidene]-2-one
A potent, selective, reversible and ATP-competitive inhibitor of GSK-3α/ β (IC50 = 5nM). Under a feeder-free condition, BIO maintains embryonic stem cells (hESCs) in the undifferented state. Group: Biochemicals. Alternative Names: (2Z,3E)-6-Bromo-3-(hydroxyimino)-[2,3-biindolinylidene]-2-one. Grades: Highly Purified. CAS No. 667463-62-9. Pack Sizes: 1mg. US Biological Life Sciences.
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BIO5192
BIO5192 is a selective and potent integrin α4β1 (VLA-4) inhibitor ( K d <10 pM). BIO5192 selectively binds to α4β1 ( IC 50 =1.8 nM) over a range of other integrins. BIO5192 results in a 30-fold increase in mobilization of murine hematopoietic stem and progenitors (HSPCs) over basal levels [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 327613-57-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-107589.
BIO 5192
BIO 5192 is a selective and potent inhibitor of integrin α4β1 (Very Late Antigen-4; VLA-4) (Kd < 10 pM) with selectivity for α4β1 over a range of other integrins (IC50 values are 1.8, 138, 1053,> 500 and > 10,000 nM for α4β1, α9β1, α2β1, α4β7 and αIIbβ3, respectively). BIO 5192 causes a 30-fold increase in mobilization of murine hematopoietic stem and progenitors (HSPCs) over basal levels. Synonyms: BIO-5192; AMD-15057; BIO 5192; AMD 15057; BIO5192; AMD15057; (2S) -2- [ [ [ (2S) -1- [ (3, 5-Dichlorophenyl) sulfonyl] -2-pyrrolidinyl] carbonyl] amino] -4- [ [ (2S) -4-methyl-2- [methyl [2- [4- [ [ [ (2-methylphenyl) amino] carbonyl] amino] phenyl] acetyl] amino] -1-oxopentyl] amino] butanoic acid. Grades: ≥98% by HPLC. CAS No. 327613-57-0. Molecular formula: C38H46Cl2N6O8S. Mole weight: 817.78.
BIO 5192
BIO 5192. Group: Biochemicals. Grades: Purified. CAS No. 327613-57-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Bio-acetoxime
BIO-acetoxime (BIA) is a potent and selective GSK-3 inhibitor, with IC50s of both 10 nM for GSK-3α/&beta. BIO-acetoxime has anticonvulsant and anti-infection activity. Group: Inhibitors. CAS No. 667463-85-6. Molecular formula: C18H12BrN3O3. Mole weight: C18H12BrN3O3. Purity: >98 %. Catalog: ACM667463856.
BIO-acetoxime
BIO-acetoxime is a potent and selective GSK-3 inhibitor, with IC50s of both 10 nM for GSK-3α/&beta. It shows >240-fold selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B. It has anticonvulsant and anti-infection activity. Synonyms: BIA; GSK-3 Inhibitor X; (2'Z,3'E)-6-Bromoindirubin-3'-acetoxime; (3Z)-3-[(3E)-3-(Acetoxyimino)-1,3-dihydro-2H-indol-2-ylidene]-6-bromo-1,3-dihydro-2H-indol-2-one; 2H-Indol-2-one, 3-[(3E)-3-[(acetyloxy)imino]-1,3-dihydro-2H-indol-2-ylidene]-6-bromo-1,3-dihydro-, (3Z)-; 6-Bromoindirubin acetoxime; 6-Bromoindirubin-3'-acetoxime. Grades: 98%. CAS No. 667463-85-6. Molecular formula: C18H12BrN3O3. Mole weight: 398.21.
BIO-acetoxime
BIO-acetoxime. Group: Biochemicals. Grades: Purified. CAS No. 667463-85-6. Pack Sizes: 1mg, 10mg. US Biological Life Sciences.
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Bioactive Compound Library
A collection of 11585 small molecule compounds with validated activity for high throughput screening (HTS), high content screening (HCS), cell induction, and target identification; - All compounds have clear targets; - An effective tool for discovering new with old drugs, cell induction, and new drug target screening; - Covers various disease research areas, such as Cancer, Metabolism, Immunology and Cardiovascular system, etc. - Detailed compound information with structure, target, activity, IC50 value, and brief introduction; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L4000. Categories: Bioactive Compounds Libraries.
Bioactive Compounds Library Max
A collection of 19703 bioactive compounds for high-throughput screening, high-content screening, cell induction and target identification. - All compounds are described with corresponding target information, which makes activity studies more evidence-based. - An effective tool for drug repurposing and cell-induced target screening. - Covers multiple areas of disease studies, such as cancer, metabolism, immune system and cardiovascular system. - Detailed instructions, compound structures, target information, activity descriptions, etc. - Structural diversity, significant drug potency and cell penetration. Uses: Scientific use. Product Category: L4010. Categories: Bioactive Compounds Libraries Max.
Bioactive Lipid Compound Library
A unique collection of 385 bioactive lipids related compounds for high throughput screening (HTS) and high content screening (HCS), including Agonists & Antagonists, Endocannabinoids, Farnesyl/geranylgeranyl derivates, HETEs deHETEs, hepoxilins, Polyunsaturated fatty acids, Leukotrienes, lipoxins, LPA & phosphatidic acids, Octadecanoids, PAFs, Prostaglandins & thromboxanes, Retinoids, vitamin D metabolites, Sphingolipids, etc. ; - Targets include GPCR, HDAC, PPAR, DNA Alkylating, EGFR, etc. ; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L7000. Categories: Bioactive Lipid Compounds Libraries.