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| Product | Description | |
|---|---|---|
| Biliverdin | Biliverdin, a tetrapyrrolic pigment, is a product of heme catabolism. Heme is broken down into Biliverdin and carbon monoxide and iron by heme oxidase. Biliverdin is then quickly broken down to bilirubin by Biliverdin reductase. Biliverdin is anti-mutagenic, an antioxidant, anti-inflammatory, and immunosuppressant [1]. Uses: Scientific research. Group: Natural products. CAS No. 114-25-0. Pack Sizes: 1 mg. Product ID: HY-135005A. |  |
| Biliverdine | Biliverdineis a precursor of Bilirubin. Biliverdine is formed in the body from hemoglobin. The bile of amphibia and of birds contains Biliverdine only. Group: Biochemicals. Alternative Names: 3,18-Diethenyl-1,19,22,24-tetrahydro-2,7,13,17-tetrametyl-1,19-dioxo-21H-biline-8,12-dipropanoic Acid; Biliverdin; Biliverdin IXα; Dehydrobilirubin; NSC 62793; Oocyan; Protobiliverdin IXα; Uteroverdine; α-Biliverdin. Grades: Highly Purified. CAS No. 114-25-0. Pack Sizes: 2.5mg. US Biological Life Sciences. |  Worldwide |
| Biliverdine-d4 | Biliverdine-d4. Group: Biochemicals. Alternative Names: 3,18-Diethenyl-1,19,22,24-tetrahydro-2,7,13,17-tetrametyl-1,19-dioxo-21H-biline-8,12-dipropanoic Acid-d4; Biliverdin-d4; Biliverdin IXα-d4; Dehydrobilirubin-d4; NSC 62793-d4; Oocyan-d4; Protobiliverdin IXα-d4; Uteroverdine-d4; α-Biliverdin-d4. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C33H30D4N4O6, Molecular Weight: 586.669999999999. US Biological Life Sciences. | Worldwide |
| Biliverdin hydrochloride | Biliverdin hydrochloride, a tetrapyrrolic pigment, is a product of heme catabolism. Heme is broken down into Biliverdin and carbon monoxide and iron by heme oxidase. Biliverdin hydrochloride is then quickly broken down to bilirubin by Biliverdin reductase. Biliverdin hydrochloride is anti-mutagenic, an antioxidant, anti-inflammatory, and immunosuppressant [1]. Uses: Scientific research. Group: Natural products. CAS No. 856699-18-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-135005. | |
| biliverdin reductase | Biliverdin reductase (BVR) is an enzyme (EC 1.3.1.24) found in all tissues under normal conditions, but especially in reticulo-macrophages of the liver and spleen. BVR facilitates the conversion of biliverdin to bilirubin via the reduction of a double-bond between the second and third pyrrole ring into a single-bond. Group: Enzymes. Enzyme Commission Number: EC 1.3.1.24. CAS No. 9074-10-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1298; biliverdin reductase; EC 1.3.1.24; 9074-10-6. Cat No: EXWM-1298. |  |
| Biliverdin Reductase A human | recombinant, expressed in E. coli, ?90% (SDS-PAGE), buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. |  |
| Billberry Leaf Powder (Vaccinium Myrtillus) | Billberry Leaf Powder (Vaccinium Myrtillus). |  CA, FL & NJ |
| Bilobalide | Bilobalide, a sesquiterpene trilactone constituent of Ginkgo biloba, inhibits the NMDA-induced efflux of choline with an IC50 value of 2.3 μM. Bilobalide prevents apoptosis through activation of the PI3K/Akt pathway in SH-SY5Y cells. Exerts protective and trophic effects on neurons. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (-)-Bilobalide. Product Category: Inhibitors. CAS No. 33570-04-6. Molecular formula: C15H18O8. Mole weight: 326.3. Purity: 0.98. Canonical SMILES: CC(C)(C)[C@@]1(C[C@H]2[C@@]3([C@]14[C@H](C(=O)O[C@H]4OC3=O)O)CC(=O)O2)O. Product ID: ACM33570046. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Bilobalide | primary reference standard. Group: Herbal medicinal products standards. | |
| Bilobalide | Bilobalide is a biologically active terpenic trilactone present in Ginkgo biloba. Synonyms: (-)-Bilobalide; Vitexicarpim; (3aS,5aR,8aS)-9R-(1,1-dimethylethyl)-10,10aS-dihydro-8R,9-dihydroxy-4H,5aH,9H-furo[2,3-b]furo[3',2':2,3]cyclopenta[1,2-c]furan-2,4,7(3H,8H)-trione. Grade: >98%. CAS No. 33570-04-6. Molecular formula: C15H18O8. Mole weight: 326.30. |  |
| Bilobalide | Bilobalide, a sesquiterpene trilactone constituent of Ginkgo biloba , inhibits the NMDA-induced efflux of choline with an IC 50 value of 2.3 μM. Bilobalide prevents apoptosis through activation of the PI3K/Akt pathway in SH-SY5Y cells. Exerts protective and trophic effects on neurons [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Bilobalide. CAS No. 33570-04-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0076. | |
| Bilobalide | Neuroprotective. Mitochondrial gene expression regulator. ROS scavenger. Competitive GABA(A) receptor antagonist. Apoptosis inhibitor. CREB phosphorylation enhancer. Stimulates neurogenesis and synaptogenesis. Hepatic cytochrome P450 inducer. Activates the phosphatidylinositol 3-kinase (PI3K) dependent pathway. Group: Biochemicals. Grades: Highly Purified. CAS No. 33570-04-6. Pack Sizes: 10mg, 50mg. Molecular Formula: C15H18O8. US Biological Life Sciences. | Worldwide |
| Bilobalide A | Bilobalide A. Group: Biochemicals. Grades: Plant Grade. CAS No. 33570-04-6. Pack Sizes: 20mg. Molecular Formula: C15H18O8, Molecular Weight: 326.3. US Biological Life Sciences. | Worldwide |
| Bilobetin | Bilobetin. Group: Biochemicals. Grades: Plant Grade. CAS No. 521-32-4. Pack Sizes: 10mg. Molecular Formula: C31H20O10, Molecular Weight: 552.49. US Biological Life Sciences. | Worldwide |
| Bilobetin | Bilobetin Inhibitor. Uses: Scientific use. Product Category: T4S2128. CAS No. 521-32-4. |  |
| BIM 187 | BIM 187 is a bombesin/GRP receptor agonist that reduces food intake following i.p. administration. Synonyms: BIM 187; BIM187; BIM-187. CAS No. 137734-88-4. Molecular formula: C53H76N14O10. Mole weight: 1069.27. | |
| BIM 187 | BIM 187. Group: Biochemicals. Grades: Purified. CAS No. 137734-88-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| BIM 189 | BIM 189. Group: Biochemicals. Grades: Purified. CAS No. 142062-55-3. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| BIM 189 | BIM 189 is a bombesin antagonist that reduces bombesin-induced satiety. Synonyms: [D-Phe6,Leu13,Cpa14]bombesin-(6-14)NH2. Grade: >96%. CAS No. 142062-55-3. Molecular formula: C56H73ClN14O10. Mole weight: 1137.73. | |
| BIM 23042 | BIM 23042. Group: Biochemicals. Grades: Purified. CAS No. 111857-96-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| BIM 23042 Acetate | BIM 23042 Acetate is a selective antagonist of neuromedin B. Molecular formula: C65H77N11O11S2. Mole weight: 1252.50. | |
| BIM 23052 | BIM 23052. Group: Biochemicals. Grades: Purified. CAS No. 133073-82-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| BIM 23056 | BIM 23056 is a somatostatin receptor ligand (Ki = 142, > 1000, 10.8, 16.6 and 5.7 nM for human cloned sst1 - 5 receptors respectively). It acts as an antagonist on SRIF14-induced [35S]-GTPγS binding at sst3 and sst5 receptors (PKB = 6.33 and 5.84, respectively). Synonyms: IM 23056; IM23056; IM-23056. Grade: >98%. CAS No. 150155-61-6. Molecular formula: C71H81N11O9. Mole weight: 1232.49. | |
| BIM 23056 | BIM 23056. Group: Biochemicals. Grades: Purified. CAS No. 150155-61-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| BIM 23056 | ?95% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| BIM 23056 acetate | BIM 23056 acetate is a potent and surmountable human recombinant somatostatin receptor antagonist (Ki = 142, >1000, 10.8, 16.6 and 5.7 nM for human cloned sst1-5 receptors, respectively). It acts as an antagonist on SRIF14-induced [35S]-GTPγS binding at sst3 and sst5 receptors (PKB = 6.33 and 5.84, respectively). Synonyms: H-D-Phe-Phe-Tyr-D-Trp-Lys-Val-Phe-D-2Nal-NH2.CH3CO2H; D-phenylalanyl-L-phenylalanyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-phenylalanyl-3-(2-naphthyl)-D-alaninamide acetic acid. Grade: ≥95%. CAS No. 2763584-06-9. Molecular formula: C73H85N11O11. Mole weight: 1292.52. | |
| BIM 23127 | BIM 23127. Group: Biochemicals. Grades: Purified. CAS No. 160161-61-5. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| BIM-23190 | BIM-23190 is a selective SSTR2 and SSTR5 agonist. Synonyms: BDBM85051. CAS No. 182153-96-4. Molecular formula: C57H79N13O12S2. Mole weight: 1202.44. | |
| BIM-23627 | BIM 23627 is a somatostatin antagonist with IC50s of 2757, 6.4, 44, 423 and 86.5 nM for five human somatostatin receptor subtypes HSST1, HSST2, HSST3, HSST4 and HSST5, respectively. It selectively binds to human somatostatin receptor subtype 2 (HSST2) with high affinity, but is completely inactive in stimulating intracellular calcium mobilization. Synonyms: H-p-Chloro-Phe-D-Cys-β-(2-pyridyl)-Ala-Trp-Lys-Val-Cys-2-Nal-NH2 (Disulfide bridge: Cys2 and Cys7). Grade: ≥90%. CAS No. 429619-37-4. Molecular formula: C58H69ClN12O8S2. Mole weight: 1161.85. | |
| BIM-46050 | BIM-46050 is a novel and potent inhibitor of human farnesyltransferase. Synonyms: BIM46050; BIM 46050; (S)-2-((R)-3-((2S,3S)-2-(((R)-2-amino-3-mercaptopropyl)amino)-3-methylpentyl)-5,5-dimethylthiazolidine-4-carboxamido)-4-(methylthio)butanoic acid. Grade: >98%. CAS No. 201487-52-7. Molecular formula: C14H12N6O. Mole weight: 480.75. | |
| BIM-46068 | BIM-46068 is a novel and potent inhibitor of human farnesyltransferase. Synonyms: BIM 46068; BIM46068; (S)-methyl 2-((R)-3-((2S,3S)-2-(((R)-2-amino-3-mercaptopropyl)amino)-3-methylpentyl)-5,5-dimethylthiazolidine-4-carboxamido)-4-(methylthio)butanoate. Grade: >98%. CAS No. 201487-53-8. Molecular formula: C17H28ClNO2. Mole weight: 494.77. | |
| BIM-46187 tetrahydrochloride | BIM-46187 tetrahydrochloride is a heterotrimeric G-protein complex inhibitor. Synonyms: 1-Propanone, 3,3'-dithiobis[2-amino-1-[(8S)-8-(cyclohexylmethyl)-5,6-dihydro-2-phenylimidazo[1,2-a]pyrazin-7(8H)-yl]-, hydrochloride (1:4), (2R,2'R)-; (2R,2'R)-3,3'-disulfanediylbis(2-amino-1-((S)-8-(cyclohexylmethyl)-2-phenyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)propan-1-one) tetrahydrochloride; PH-064 4HCl; BIM-46187 4HCl; BIM46187 tetrahydrochloride; BIM 46187 tetrahydrochloride. Grade: ≥95%. CAS No. 2489449-03-6. Molecular formula: C44H58N8O2S2.4HCl. Mole weight: 940.96. | |
| BIM5078 | Hepatocyte nuclear factor (HNF)4α is a key regulator of gene expression in cell types playing an important role in metabolic homeostasis, such as hepatocytes, enterocytes, as well as pancreatic β cells. BIM5078 is a potent hepatocyte nuclear factor 4a (HNF4a) antagonist that directly binds to ligand-binding pocket of HNF4α with an EC50 value of 11.9 nM and modulates the expression of known HNF4a target genes. The EC50 of BIM5078 was calculated to be 11.9 nM and further analyses of the data using the Hill equation showed that the Hill coefficient for BIM5078 was 0.9, consistent with a single binding complex between BIM5078 and HNF4α. Grade: ≥98%. CAS No. 337506-43-1. Molecular formula: C14H10ClN3O4S. Mole weight: 351.8. | |
| BIM5078 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Bimagrumab | Bimagrumab (Anti-ACVR2B Reference Antibody) is a human monoclonal antibody that blocks activin type II receptor (ActRII) , with K D s of 1.7 pM and 434 pM for human ActRIIB and ActRIIA , respectively. Bimagrumab can be used for the research of pathological muscle loss and weakness [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-ACVR2B Reference Antibody; BYM338. CAS No. 1356922-05-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99355. | |
| Bimatoprost | Bimatoprost is an antiglaucoma agent. Bimatoprost is an synthetic prostamide; structurally related to prostaglandin F2α. Group: Biochemicals. Alternative Names: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-ethyl-5-heptenamide; AGN-192024; Lumigan; Prostamide. Grades: Highly Purified. CAS No. 155206-00-1. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Bimatoprost | 25mg Pack Size. Group: Building Blocks, Organics, Research Organics & Inorganics. Formula: C25H37NO4. CAS No. 155206-00-1. Prepack ID 15060220-25mg. Molecular Weight 415.57. See USA prepack pricing. |  |
| Bimatoprost | Bimatoprost is a prostaglandin analog that reduces intraocular pressure by regulating scleral and trabecular outflow. Bimatoprost is used in the study of open-angle glaucoma, ocular hypertension, and other forms of glaucoma. Topical application of bimatoprost induces fat atrophy and causes a deepening of the eyelid sulcus [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AGN 192024. CAS No. 155206-00-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0191. | |
| Bimatoprost | Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Uses: For research used only. Synonyms: AGN 192024; AGN192024; AGN-192024; Bimatoprost; Lumigan; Latisse; Bimatoprostum; Lumigan. Grade: >98%. CAS No. 155206-00-1. Molecular formula: C25H37NO4. Mole weight: 415.57. | |
| Bimatoprost 13,14-Epoxide | Bimatoprost 13,14-Epoxide is one of bimatoprost impurities. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Synonyms: 17-Phenyl-18,19,20-trinor-PGF2α 13,14-Epoxide; Bimatoprost Impurity 2 (Mixture of Diastereomers). Molecular formula: C25H37NO5. Mole weight: 431.56. | |
| Bimatoprost 13,14-Epoxide | Bimatoprost 13,14-Epoxide is the impurity of Bimatoprost (B386800), which is an antiglaucoma agent. Bimatoprost is an synthetic prostamide; structurally related to prostaglandin F2α. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C25H37NO5, Molecular Weight: 431.56. US Biological Life Sciences. | Worldwide |
| Bimatoprost Acid | Bimatoprost Acid is an impurity of the antiglaucoma agent Bimatoprost. It is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-5-heptenoic Acid; 17-Phenyl-18,19,20-trinor-PGF2α; PhXA 70; (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-pentenyl]cyclopentyl]-5-heptenoic Aci. Grade: > 95%. CAS No. 38344-08-0. Molecular formula: C23H32O5. Mole weight: 388.51. | |
| Bimatoprost Acid Methyl Ester | Bimatoprost Acid Methyl Ester is an impurity of the antiglaucoma agent Bimatoprost. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-5-heptenoic Acid Methyl Ester; 17-Phenyl-18,19,20-trinor-PGF2α Methyl Ester. Grade: > 95%. CAS No. 38315-47-8. Molecular formula: C24H34O5. Mole weight: 402.54. | |
| Bimatoprost Impurity 10 | Bimatoprost Impurity 10 is one of bimatoprost impurities. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Molecular formula: C25H43NO6. Mole weight: 453.61. | |
| Bimatoprost Impurity 11 | Bimatoprost Impurity 11 is one of bimatoprost impurities. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Molecular formula: C25H41NO6. Mole weight: 451.59. | |
| Bimatoprost Impurity 13 | Bimatoprost Impurity 13 is one of bimatoprost impurities. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Molecular formula: C35H51NO6. Mole weight: 581.78. | |
| Bimatoprost Impurity 14 | Bimatoprost Impurity 14 is one of bimatoprost impurities. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Molecular formula: C35H53NO6. Mole weight: 583.80. | |
| Bimatoprost Impurity 3 | Bimatoprost Impurity 3 is one of bimatoprost impurities. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Molecular formula: C23H33NO4. Mole weight: 387.51. | |
| Bimatoprost Impurity 9 | Bimatoprost Impurity 9 is one of bimatoprost impurities. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Molecular formula: C34H63NO6Si. Mole weight: 609.95. | |
| Bim BH3 | Bim BH3 is a biological active peptide. (This Bim peptide belongs to the pro-apoptotic Bcl-2 family of proteins.). Uses: Scientific research. Group: Peptides. CAS No. 505070-06-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P1527. | |
| Bim BH3, Peptide IV | It is a 26-residue peptide from BH3-only protein Bim, belonging to the pro-apoptotic group of the Bcl-2 family of proteins. Synonyms: L-Arginine, L-α-aspartyl-L-methionyl-L-prolyl-L-arginyl-L-α-glutamyl-L-isoleucyl-L-tryptophyl-L-isoleucyl-L-alanyl-L-glutaminyl-L-α-glutamyl-L-leucyl-L-arginyl-L-arginyl-L-isol; Asp-Met-Arg-Pro-Glu-Ile-Trp-Ile-Ala-Gln-Glu-Leu-Arg-Arg-Ile-Gly-Asp-Glu-Phe-Asn-Ala-Tyr-Tyr-Ala-Arg-Arg. Grade: >98%. CAS No. 2088247-34-9. Molecular formula: C145H222N44O41S. Mole weight: 3269.65. | |
| BIM (Biotin) | BIM (Biotin). Group: Biochemicals. Grades: Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| BIM, Biotinylated | Bim peptide fragment (residues 81-106) with a biotin moiety attached. Molecular formula: C161H247N49O44S2. Mole weight: 3637.14. | |
| Bi-Mc-VC-PAB-MMAE | Bi-Mc-VC-PAB-MMAE consists ADCs linker (Bi-Mc-Val-Cit-PAB) and potent tubulin inhibitor (MMAE, HY-15162). Bi-Mc-VC-PAB-MMAE is a drug-linker conjugate for ADC. Uses: Scientific research. Group: Signaling pathways. CAS No. 1620837-70-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-141833. | |
| Bimekizumab | Bimekizumab (Anti-Human IL17A/IL-17F Recombinant Antibody) is a humanised monoclonal antibody, can selectively neutralises IL-17A and IL-17F. Both of them are pro-osteogenic with respect to human periosteum-derived cell (hPDC) differentiation. Thus Bimekizumab blocks the inflammation-driven osteogenic differentiation [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human IL17A/IL-17F Recombinant Antibody. CAS No. 1418205-77-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99280. | |
| Bim-IN-1 | Bim-IN-1 is a potent Bim expression inhibitor. Bim-IN-1 reduces Bim expression levels and has little inhibitory effect upon protein kinase A activity and minimal toxicity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2909483-36-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115930. | |
| Bimiralisib | Bimiralisib (PQR309) is a potent, brain-penetrant, orally bioavailable, pan-class I PI3K/mTOR inhibitor with IC50s of 33 nM, 451 nM, 661 nM, 708 nM and 89 nM for PI3K?, PI3K?, PI3K?, PI3K? and mTOR, respectively. Bimiralisib is an mTORC1 and mTORC2 inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PQR309. CAS No. 1225037-39-7. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12868. | |
| Bimiralisib free base | Bimiralisib, also known as PQR309, is an orally bioavailable pan inhibitor of phosphoinositide-3-kinases (PI3K) and inhibitor of the mammalian target of rapamycin (mTOR), with potential antineoplastic activity. PI3K/mTOR kinase inhibitor PQR309 inhibits the PI3K kinase isoforms alpha, beta, gamma and delta and, to a lesser extent, mTOR kinase, which may result in tumor cell apoptosis and growth inhibition in cells overexpressing PI3K/mTOR. Activation of the PI3K/mTOR pathway promotes cell growth, survival, and resistance to both chemotherapy and radiotherapy. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PQR309; PQR-309; PQR309; Bimiralisib free base. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1225037-39-7. Molecular formula: C17H20F3N7O2. Mole weight: 411.39. Purity: >98%. IUPACName: 5-(4,6-dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine. Canonical SMILES: NC1=NC=C(C2=NC(N3CCOCC3)=NC(N4CCOCC4)=N2)C(C(F)(F)F)=C1. Product ID: ACM1225037397. Alfa Chemistry ISO 9001:2015 Certified. | |
| Bimoclomol | Bimoclomol is a heat shock protein (HSP) coinducer, used for treatment of cardiovascular diseases. Uses: Scientific research. Group: Signaling pathways. CAS No. 130493-03-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00398. | |
| Bimoclomol | Bimoclomol is a heat shock protein (HSP) coinducer that exhibits cytoprotective effects. It can be used in the treatment of cardiovascular diseases. Synonyms: (3Z)-N-(2-hydroxy-3-piperidin-1-ylpropoxy)pyridine-3-carboximidoyl chloride; bimoclomol; bimoclomol, maleate (1:1). CAS No. 130493-03-7. Molecular formula: C14H20ClN3O2. Mole weight: 297.78. | |
| Bimolane | Bimolane is a topoisomerase II inhibitor. It has been widely used as an anti-neoplastic agent and for the treatment of psoriasis in China. Bimolane is also a leukemogenic agent and is thought to exert its effects through the inhibition of topoisomerase II. Uses: Psoriasis. Synonyms: Bimolane; 4,4'-Ethylenebis[1-(morpholinomethyl)-2,6-piperazinedione]; AT-1727; AT1727; AT 1727; CCRIS 7574; CCRIS7574; CCRIS-7574; NSC 351358. Grade: 98%. CAS No. 74550-97-3. Molecular formula: C20H32N6O6. Mole weight: 452.51. | |
| Bimolane | Bimolane (AT-1727), a human topoisomerase II inhibitor, can be used as an anti-neoplastic agent and for the research of psoriasis. Bimolane shows leukemogenic activity and induces multiple types of chromosomal aberrations in human lymphocytes. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Bimolane;4,4'-Ethylenebis[1-(morpholinomethyl)-2,6-piperazinedione];AT-1727. Product Category: Inhibitors. CAS No. 74550-97-3. Molecular formula: C20H32N6O6. Product ID: ACM74550973. Alfa Chemistry ISO 9001:2015 Certified. Categories: Bimala Nepali. | |
| Bimosiamose | Bimosiamose (TBC-1269) is a nonoligosaccharide pan-selectin antagonist with IC50s of 88 ?M, 20 ?M, and 86 ?M for E-selectin, P-selectin, and L-selectin, respectively. Bimosiamose has anti-inflammatory effects[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TBC-1269. CAS No. 187269-40-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106139. | |
| Bimosiamose disodium | Bimosiamose disodium. Grade: 95%. CAS No. 187269-60-9. Molecular formula: C46H52Na2O16. Mole weight: 906.8808. | |
| BIMU 8 | BIMU 8 is a potent and selective 5-HT4 receptor full agonist (KD = 77 nM and EC50 = 18 nM for wild type 5-HT4 receptors). Synonyms: BIMU 8; BIMU8; BIMU-8; 2,3-Dihydro-N-[(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]-3-(1-methylethyl)-2-oxo-1H-benzimidazole-1-carboxamide hydrochloride; N-[(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-3-propan-2-ylbenzimidazole-1-carboxamide hydrochloride. Grade: ≥98% by HPLC. CAS No. 134296-40-5. Molecular formula: C19H26N4O2.HCl. Mole weight: 378.9. | |
| BIMU 8 | BIMU 8. Group: Biochemicals. Grades: Purified. CAS No. 134296-40-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BIMU 8 | BIMU 8 is a potent and selective 5-HT4 agonist with EC 50 s of 18 nM, 77 nM, and 540 nM for wild type 5HT4 receptor , T3.36A , and W6.48A mutant 5-HT4 receptors [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 134296-40-5. Pack Sizes: 1 mg. Product ID: HY-110094. | |
| BIMU8 hydrate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BIN1b | Bin1b is a beta-defensins-like molecule originally isolated from the rat epididymis. | |
| BINA | BINA is a selective positive allosteric modulator of mGlu2 (EC50 = 33.2 nM in CHO cells expressing human mGlu2) with no effect on glutamate-induced activation of other mGlu receptor subtypes. BINA exhibits antipsychotic and anxiolytic properties in mice. Synonyms: 3'-[[(2-Cyclopentyl-2,3-dihydro-6,7-dimethyl-1-oxo-1H-inden-5-yl)oxy]methyl]-[1,1'-biphenyl]-4-carboxylic acid; Biphenylindanone A; Biphenyl-indanone A. Grade: ≥98% by HPLC. CAS No. 866823-73-6. Molecular formula: C30H30O4. Mole weight: 454.56. | |
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