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| Product | Description | |
|---|---|---|
| Bh3i-1 | BH3I-1 is a Bcl-2 family antagonist, which inhibits the binding of the Bak BH3 peptide to Bcl-xL with a Ki of 2.4±0.2 μM in FP assay. BH3I-1 has a Kd of 5.3 μM against the p53/MDM2 pair. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 300817-68-9. Molecular formula: C15H14BrNO3S2. Mole weight: 400.316. Purity: ≥98.0%. Product ID: ACM300817689. Alfa Chemistry ISO 9001:2015 Certified. Categories: BH3 interacting-domain death agonist. |  |
| BH3I-1 | BH3I-1 is a cell-permeable inhibitor that targets Bcl-2 family protein. It inhibits the binding of BH3 peptides to Bcl-xL and induces apoptosis of Bcl-xL expressing cells. Synonyms: BH3I-1; BH 3I-1; BH-3I-1; BH3I1; BH 3I1; BH-3I1. 2-[(5E)-5-[(4-bromophenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-3-methylbutanoic acid. Grades: 99%. CAS No. 300817-68-9. Molecular formula: C15H14BrNO3S2. Mole weight: 400.31. |  |
| BH-9PA | BH-9PA. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 9-(10-Phenylanthracen-9-yl)spiro-[benzo[c]fluorene-7,9'-fluorene]. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1262281-88-8. Molecular formula: C49H30. Mole weight: 618.76 g/mol. Product ID: ACM1262281888. Alfa Chemistry ISO 9001:2015 Certified. Categories: Bhopal disaster. | |
| BHA | BHA (Butylated Hydroxy Anisole). CAS No. 25013-16-5. FEMA No. 2183. Kosher: Y. VIGON Item # 500563. Categories: Speciality Ingredients Suppliers, Flavors, Fragrances, Perfumers. |  America & Internationally |
| BHA-polystyrene | BHA-polystyrene. Group: Polystyrene (ps). |  |
| BHHT | BHHT. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,1'-[1,1':2',1''-Terphenyl]-4,4''-diylbis[4,4,5,5,6,6,6-heptafluoro-1,3-hexanedione. Product Category: Other Fluorophores. CAS No. 200862-69-7. Molecular formula: C30H16F14O4. Mole weight: 706.42. Purity: 95%+. IUPACName: 4,4,5,5,6,6,6-heptafluoro-1-[4-[2-[4-(4,4,5,5,6,6,6-heptafluoro-3-oxohexanoyl)phenyl]phenyl]phenyl]hexane-1,3-dione. Canonical SMILES: C1=CC=C(C(=C1)C2=CC=C(C=C2)C(=O)CC(=O)C(C(C(F)(F)F)(F)F)(F)F)C3=CC=C(C=C3)C(=O)CC(=O)C(C(C(F)(F)F)(F)F)(F)F. Density: 1.453 ± 0.06 g/ml. Product ID: ACM200862697-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: Bharatiya Janata Party. | |
| Bhimamycin A | Bhimamycin is an antibiotic produced by Streptomyces sp. GW32/698. Five components A to E are separated. Bhimamycin A has moderate activity against gram-positive and gram-negative bacteria. Molecular formula: C15H12O5. Mole weight: 272.25. | |
| Bhimamycin B | Bhimamycin is an antibiotic produced by Streptomyces sp. GW32/698. Five components A to E are separated. Bhimamycin B has moderate activity against gram-positive and gram-negative bacteria. Molecular formula: C15H10O5. Mole weight: 270.24. | |
| Bhimamycin C | Bhimamycin is an antibiotic produced by Streptomyces sp. GW32/698. Five components A to E are separated. Bhimamycin C has no antibacterial activity. Molecular formula: C17H17NO5. Mole weight: 315.32. | |
| Bhimamycin D | Bhimamycin is an antibiotic produced by Streptomyces sp. GW32/698. Five components A to E are separated. Bhimamycin D has no antibacterial activity. Molecular formula: C22H15NO6. Mole weight: 389.36. | |
| Bhimamycin E | Bhimamycin is an antibiotic produced by Streptomyces sp. GW32/699. Five components A to E are separated. Bhimamycin E selectively inhibits Staphylococcus aureus. Molecular formula: C13H10O5. Mole weight: 246.21. | |
| BHP | BHP is an antibacterial peptide isolated from Bos taurus. | |
| BHPI | BHPI is an antagonist of estrogen receptor α (ERα), for it elicits sustained ERα-dependent activation of the endoplasmic reticulum (EnR) stress sensor. Uses: An antagonist of estrogen receptor α (erα). Synonyms: 1,3-dihydro-3,3-bis(4-hydroxyphenyl)-7-methyl-2H-indol-2-one. Grades: ≥95%. CAS No. 56632-39-4. Molecular formula: C21H17NO3. Mole weight: 331.4. | |
| BHQ | BHQ. Group: Biochemicals. Grades: Purified. CAS No. 88-58-4. Pack Sizes: 100mg. US Biological Life Sciences. |  Worldwide |
| BHQ-1-dT | BHQ-1-dT, a widely utilized reagent in the biomedicine realm, remains pertinent for nucleic acid detection and DNA sequencing. Its potential significance surfaces in disease and genetic disorder determination alongside viral load monitoring in infectious cases. From a development standpoint, BHQ-1-dT fosters therapeutic targeting of nucleic acids. Synonyms: 5'-Dimethoxytrityloxy-5-[(N-4''-carboxyethyl-4''-(N-ethyl)-4'-(2-Nitro-4-toluyldiazo)-2'-methoxy-5'-methyl-azobenzene)-aminohexyl-3-acrylimido]-2'-deoxyUridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C74H89N12O14P. Mole weight: 1401.56. | |
| BHQ-2-dT | BHQ-2-dT plays a critical role in propelling PCR probes and hybridization assays to new heights of detection, this modified nucleoside serves as a beacon for identifying viral pathogens, genetic diseases, and cancer biomarkers. With its distinctive fluorescent abilities, molecular matching is taken to the next level of precision and accuracy, boosting sensitivity like never before. Synonyms: 5'-Dimethoxytrityloxy-5-[(N-4''-carboxyethyl-4''-(N-ethyl)-4'-(4-Nitro-phenyldiazo)-2'-methoxy-5'-methoxy-azobenzene)-aminohexyl-3-acrylimido]-2'-deoxyUridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. CAS No. 1415097-34-5. Molecular formula: C73H87N12O15P. Mole weight: 1403.53. | |
| BHT | BHT (Butylated Hydroxy Toluene). CAS No. 128-37-0. FEMA No. 2184. Kosher: Y. VIGON Item # 500473. Categories: Speciality Ingredients Suppliers, Flavors, Fragrances, Perfumers. | America & Internationally |
| B-HT 920 | B-HT 920. Group: Biochemicals. Grades: Purified. CAS No. 36085-73-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| B-HT 920 dihydrochloride | Talipexole is a D2 dopamine receptor agonist, displaying anti-Parkinsonian activity. Uses: A dopamine agonist, also an α2-adrenergic agonist. Synonyms: Talipexole; B-HT 920, B-HT-920, B-HT920, Talipexole HCl, Talipexole dihydrochloride, Domnin6-prop-2-enyl-4,5,7,8-tetrahydro-[1,3]thiazolo[4,5-d]azepin-2-amine;dihydrochloride;5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepine-2-amine dihydrochloride. Grades: ≥98%. CAS No. 36085-73-1. Molecular formula: C10H15N3S 2HCl. Mole weight: 282.23. | |
| B-HT 920 dihydrochloride talipexole | B-HT 920 dihydrochloride talipexole. Group: Biochemicals. Alternative Names: 5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepin-2-amine dihydrochloride, 6-allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine dihydrochloride. Grades: Highly Purified. CAS No. 36085-73-1. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C10H17Cl2N3S. US Biological Life Sciences. | Worldwide |
| B-HT 920 Dihydrochloride. Talipexole (5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepin-2-amine Dihydrochloride, 6-Allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine Dihydrochloride) | An alpha 2-Adrenoceptor and dopamine D2-receptor agonist. Used as an antiparkinson reagent. Group: Biochemicals. Alternative Names: 5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepin-2-amine Dihydrochloride, 6-Allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine Dihydrochloride. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| B-HT 933 dihydrochloride | B-HT 933 dihydrochloride is a selective α2-adrenoceptor agonist displaying 300-fold selectivity for the α2-adrenoceptor over the α1-adrenoceptor. B-HT 933 decreases blood pressure and cardiac output in cats, and exhibits antinociceptive activity in mice. Uses: Adrenergic alpha-agonists. Synonyms: B-HT 933 dihydrochloride; B-HT933 dihydrochloride; B-HT-933 dihydrochloride; Azepexole hydrochloride; Azepexole dihydrochloride; 6-Ethyl-5,6,7,8-tetrahydro-4H-oxazolo[4,5-d]azepin-2-amine dihydrochloride. Grades: ≥99% by HPLC. CAS No. 36067-72-8. Molecular formula: C9H15N3O.2HCl. Mole weight: 254.16. | |
| B-HT 933 dihydrochloride | B-HT 933 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 36067-72-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| B-HT 958 dihydrochloride | B-HT 958 dihydrochloride is a dopamine D2 receptor agonist and an α2-adrenoceptor partial agonist. Synonyms: B-HT 958 dihydrochloride; B-HT958 dihydrochloride; B-HT-958 dihydrochloride; 4H-Thiazolo(4,5-d)azepin-2-amine, 5,6,7,8-tetrahydro-6-((4-chlorophenyl)methyl)-, dihydrochloride; 2-Amino-6-(4-chlorobenzyl)-4,5,7,8-tetrahydro-6H-thiazolo(5,4-d)azepine dihydrochloride; 5,6,7,8-Tetrahydro-6-((4-chlorophenyl)methyl)-4H-thiazolo(4,5-d)azepin-2-amine dihydrochloride. Grades: 99%. CAS No. 36085-44-6. Molecular formula: C14H16ClN3S.2HCl. Mole weight: 366.74. | |
| BHT-A1 | BHT-A1 is produced by Streptococcus rattus BHT. It is active against Gram-positive bacterials. | |
| BHT-B | BHT-B is produced by Streptococcus rattus BHT. BHT-B is a non-modified 5195Da peptide with some similarity to the tryptophan-rich Staphylococcus aureus bacteriocin, aureocin A53. | |
| b-Hydroxytamoxifen (trans- (Z) -1-[4-[2- (Dimethylamino) ethoxy]phenyl]-1, 2-diphenyl-1-butene-4-ol) | A hydroxylated analogue of tamoxifen with anti-estrogenic properties. Group: Biochemicals. Alternative Names: trans- (Z) -1-[4-[2- (Dimethylamino) ethoxy]phenyl]-1, 2-diphenyl-1-butene-4-ol. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| BI 01383298 | BI01383298 is a potent and selective inhibitor of human SLC13A5 (Na+/citrate co-transporter) with IC50 of 56 nM in HEK cells overexpressing hSLC13A5. BI01383298 is highly selective over other family members and other transporters with >1000-fold selectivity over others. Synonyms: 1-[(3,5-Dichlorophenyl)sulfonyl]-N-[(4-fluorophenyl)methyl]-4-piperidinecarboxamide. Grades: ≥98%. CAS No. 2227549-00-8. Molecular formula: C19H19Cl2FN2O3S. Mole weight: 445.34. | |
| B I09 | B I09 is a cell permeable IRE-1 RNase inhibitor (IC50 = 1.23 μM) that blocks IRE-1/XBP1 pathway. B I09 exhibits an inhibitory effect on growth of human chronic lymphocytic leukemia (CLL) cells in vitro and promotes CLL regression in a mouse model. Uses: Potential treatment of cll. Synonyms: B-I09; B I09; BI09; 7-(1,3-Dioxan-2-yl)-1,2,3,4-tetrahydro-8-hydroxy-5H-[1]benzopyrano[3,4-c]pyridin-5-one. Grades: ≥98% by HPLC. CAS No. 1607803-67-7. Molecular formula: C16H17NO5. Mole weight: 303.31. | |
| BI-167107 | BI-167107 is a β-arrestin-biased D2R agonist that binds to β2 adrenergic receptor (β2AR) with a dissociation constant Kd of 84 pM. Synonyms: BI 167107; BI167107. Grades: 98%. CAS No. 1202235-68-4. Molecular formula: C21H26N2O4. Mole weight: 370.4. | |
| BI 224436 | BI 224436 is a novel HIV-1 noncatalytic site integrase inhibitor with EC 50 values of less than 15 nM against different HIV-1 laboratory strains. Uses: Scientific research. Group: Signaling pathways. CAS No. 1155419-89-8. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18595. |  |
| BI 224436 | BI 224436 is a novel HIV-1 non-catalytic-site integrase inhibitor; has antiviral EC50s of <15 nM against different HIV-1 laboratory strains and cellular cytotoxicity of>90 μM. Synonyms: BI-224436; BI 224436; BI224436. Grades: >98%. CAS No. 1155419-89-8. Molecular formula: C27H26N2O4. Mole weight: 442.51. | |
| Bi 2536 | BI 2536 is a dual PLK1 and BRD4 inhibitor with IC50s of 0.83 and 25 nM, respectively. BI-2536 suppresses IFNB (encoding IFN-β) gene transcription. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BI 2536;BI-2536, BoehringerPLK-1 inhibitor;4-[[(7R)-8-Cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)benzamide;Benzamide,4-[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-;Boehringer PLK-1 inhibitor;BI-2536(R-);BI2536/BI-2536;(R)-4-((8-cyclopentyl-7-ethyl-5-Methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl)aMino)-3-Methoxy-N-(1-Methylpiperidin-4-yl)benzaMide. Product Category: Inhibitors. CAS No. 755038-02-9. Molecular formula: C28H39N7O3. Mole weight: 521.662. Purity: 0.9979. Density: 1.28. Product ID: ACM755038029. Alfa Chemistry ISO 9001:2015 Certified. | |
| BI-2536 | BI-2563 is a small molecule compound with potential antineoplastic activities. BI 2536 binds to and inhibits Polo-like kinase 1 (Plk1), resulting in mitotic arrest, disruption of cytokinesis, and apoptosis in susceptible tumor cell populations. Plk1, a serine/threonine-protein kinase, is a key regulator of multiple processes fundamental to mitosis and cell division. Synonyms: BI2536; BI 2536. Grades: 0.98. CAS No. 755038-02-9. Molecular formula: C28H39N7O3. Mole weight: 521.65. | |
| BI-2545 | BI-2545 is a potent autotaxin (ATX) inhibitor that significantly reduces LPA, with IC 50 s of 2.2 nM and 3.4 nM for human ATX and rat ATX, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2162961-71-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124772. | |
| BI-2852 | BI-2852 is a KRAS inhibitor. It blocks the interaction of GEF, GAP and effectors with KRAS, thereby inhibiting downstream signal transduction and producing anti-proliferative effects in KRAS mutant cells. Synonyms: BI-2852; 2375482-51-0; CHEMBL4750445; (3~{S})-3-[2-[[[1-[(1-methylimidazol-4-yl)methyl]indol-6-yl]methylamino]methyl]-1~{H}-indol-3-yl]-5-oxidanyl-2,3-dihydroisoindol-1-one; (3S)-5-hydroxy-3-[2-[[[1-[(1-methylimidazol-4-yl)methyl]indol-6-yl]methylamino]methyl]-1H-indol-3-yl]-2,3-dihydroisoindol-1-one; F0K; SCHEMBL24414712; BCP31539; EX-A4793; BDBM50549225; s8959; AKOS040732592; BI2852; BI 2852; MS-29593; HY-126247; CS-0100975; A934943; (S)-5-Hydroxy-3-(2-((((1-((1-methyl-1H-imidazol-4-yl)methyl)-1H-indol-6-yl)methyl)amino)methyl)-1H-indol-3-yl)isoindolin-1-one; (S)-5-hydroxy-3-(2-(((1-((1-methyl-1H-imidazol-4-yl)methyl)-1H-indol-6-yl)methylamino)methyl)-1H-indol-3-yl)isoindolin-1-one. Grades: ≥98% by HPLC. CAS No. 2375482-51-0. Molecular formula: C31H28N6O2. Mole weight: 516.6. | |
| Bi2Te3 Crystal | Bi2Te3 Crystal. Uses: Designed for use in research and industrial production. Additional or Alternative Names: bismuthsesquitelluride;bismuthtelluride(bi2te3);bismuthtelluride,undoped;bismuthtritelluride;tellurobismuthite;tellururedebismuth;BISMUTH TELLURIDE;BISMUTH (III) TELLURIDE. Product Category: Graphene-like Materials Series. CAS No. 1304-82-1. Molecular formula: Bi2Te3. Mole weight: 800.76. Purity: 0.99995. Product ID: ACM1304821. Alfa Chemistry ISO 9001:2015 Certified. | |
| BI-3406 | BI-3406 is a potent and selective inhibitor of the interaction between KRAS and Son of Sevenless 1 (SOS1). SOS1 is the guanine nucleotide exchange factor (GEF) and activator of RAS, and mutants of RAS are major oncogenes and occur in many human cancers. Inhibition of SOS1 in a mutant KRAS cell line can suppress tumor growth. Synonyms: BI 3406; BI3406. CAS No. 2230836-55-0. Molecular formula: C23H25F3N4O3. Mole weight: 462.5. | |
| BI-3406 | BI-3406 is Potent & Selective SOS1:KRAS Inhibitor (IC50=5 nM), which Opens a New Approach for Treating KRAS-Driven Tumours. BI 3406 selectively binds to SOS1 and blocks the interaction with KRAS, irrespective of the KRAS mutation. BI 3406 causes RAS GTP and pERK reduction and inhibits cell growth of KRAS mutated cell lines, carrying most of the typical KRAS mutations (i.e. G12D, G12V, G13D and others). BI 3406, when administered orally to tumour bearing mice, causes a dose dependent tumour static effect that can be converted into regressions when combined with MEK1 inhibition. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BI-3406; BI 3406; BI3406. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2230836-55-0. Molecular formula: C23H25F3N4O3. Mole weight: 462.47. Purity: >98%. IUPACName: N-((R)-1-(3-amino-5-(trifluoromethyl)phenyl)ethyl)-7-methoxy-2-methyl-6-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-4-amine. Canonical SMILES: C[C@H](C1=CC(N)=CC(C(F)(F)F)=C1)NC2=C3C(C=C(OC)C(O[C@H]4CCOC4)=C3)=NC(C)=N2. Product ID: ACM2230836550. Alfa Chemistry ISO 9001:2015 Certified. | |
| BI-3802 | BI-3802 is a highly potent BCL6 degrader that inhibits the Bric-à-brac (BTB) domain of BCL6 with an IC50 of ≤3 nM. It induces BCL6 polymerization and degradation via E3 ligase SIAH1, showing antitumor activity. Grades: ≥98% by HPLC. CAS No. 2166387-65-9. Molecular formula: C24H29ClN6O3. Mole weight: 484.98. | |
| BI-3812 | BI-3812 is potent and efficacious BCL6 inhibitor. It inhibits the BTB domain of BCL6 with an IC50 of ≤3 nM. The high potency and good permeability properties of BI-3812 make this molecule a very good cellular probe compound for testing hypotheses around BCL6 biology. The transcription factor BCL6 is a known driver of oncogenesis in lymphoid malignancies, including diffuse large B cell lymphoma (DLBCL). Synonyms: BI-3812; 2166387-64-8; CHEMBL4755229; 1-(5-chloro-4-((8-methoxy-1-methyl-3-(2-(methylamino)-2-oxoethoxy)-2-oxo-1,2-dihydroquinolin-6-yl)amino)pyrimidin-2-yl)-N,N-dimethylpiperidine-4-carboxamide; SCHEMBL20284237; AMY16876; BCP31903; EX-A2841; BDBM50546197; s8735; AKOS040741329; SB40386; BI 3812; BI3812; AC-31571; MS-30157; HY-111381; CS-0040299; A935150; EN300-22885148; Z3417458909; 1-[5-chloro-4-({8-methoxy-1-methyl-3-[(methylcarbamoyl)methoxy]-2-oxo-1,2-dihydroquinolin-6-yl}amino)pyrimidin-2-yl]-N,N-dimethylpiperidine-4-carboxamide; 1-[5-Chloro-4-({8-methoxy-1-methyl-3-[2-(methylamino)-2-oxoethoxy]-2-oxo-1,2-dihydro-6-quinolinyl}amino)-2-pyrimidinyl]-N,N-dimethyl-4-piperidinecarboxamide; 1-[5-chloro-4-[[8-methoxy-1-methyl-3-[2-(methylamino)-2-oxoethoxy]-2-oxoquinolin-6-yl]amino]pyrimidin-2-yl]-N,N-dimethylpiperidine-4-carboxamide. Grades: ≥98%. CAS No. 2166387-64-8. Molecular formula: C26H32ClN7O5. Mole weight: 558.03. | |
| BI-4394 | BI-4394 (MMP13-IN-3) is a potent, selective, and orally active MMP-13 inhibitor ( IC 50=1 nM [1] ) for the potential treatment of osteoarthritis [2]. BI-4394 is >1000 selective over other MMPs [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MMP13-IN-3. CAS No. 1222173-37-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124029. | |
| BI-44847 | BI-44847 is a synthetic bio-active chemical had been in phase II clinical trials for the treatment of type 2 diabetes. Uses: Sodium-glucose transporter 2 inhibitors. Synonyms: BI-44847; BI 44847; BI44847; UNII-43WJ33399D; beta-D-Glucopyranoside,4-((2-fluoro-4-methoxyphenyl)methyl)- 5-methyl-1-(1-methylethyl)-1H-pyrazol-3-yl. Grades: ≥98%. CAS No. 421592-30-5. Molecular formula: C21H29FN2O7. Mole weight: 440.46. | |
| BI-4834 | BI-4834 is a potent and selective Polo-like kinase 1 (PLK1) inhibitor. Synonyms: BI4834; BI 4834. Grades: >98%. CAS No. 876371-13-0. Molecular formula: C21H42N4O3S3. Mole weight: 593.76. | |
| BI 6015 | BI 6015 is a hepatocyte nuclear factor 4α (HNF4α) antagonist that suppresses expression of known HNF4α target genes. BI 6015 produces cytotoxicity in a range of tumor cell lines, including human hepatocellular carcinoma. Synonyms: BI6015; BI 6015; BI-6015. 2-Methyl-1-[(2-methyl-5-nitrophenyl)sulfonyl]-1H-benzimidazole. Grades: ≥98% by HPLC. CAS No. 93987-29-2. Molecular formula: C15H13N3O4S. Mole weight: 331.35. | |
| BI 6015 | BI 6015. Group: Biochemicals. Grades: Purified. CAS No. 93987-29-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BI605906 | BI605906 is a novel pharmacological inhibitors of the IKK family. It inhibits IKKβ with an IC50 value of 380 nM when assayed at 0.1 mM ATP in vitro. It also inhibits TNFα-dependent IκB degradation and expression of pro-inflammatory mediators IL-6, IL-1b, and CXCL1/2. It not only prevents the phosphorylation of physiological substrates, but also prevents the phosphorylation of the serine residues in IKKβ that trigger its activation. Uses: Bi605906 not only prevents the phosphorylation of physiological substrates, but also prevents the phosphorylation of the serine residues in ikkβ that trigger its activation. Synonyms: BI605906; BI-605906; BI 605906;3-AMino-4-(1,1-difluoropropyl)-6-(4-Methylsulfonylpiperidin-1-yl)thieno[2,3-b]pyridine-2-carboxaMide. Grades: >98 %. CAS No. 960293-88-3. Molecular formula: C17H22F2N4O3S2. Mole weight: 432.51. | |
| BI 639667 | BI 639667 (compound 19n), a third azaindazole series compound, is a CCR1 antagonist, with an IC 50 of 1.8 nM in Ca 2+ flux assay [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CCR1 antagonist 8. CAS No. 1295298-26-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-120588. | |
| BI671800 | BI671800 is a CRTH2 antagonist. It is used to treat patients with asthma. It is associated with a small improvement in FEV1 in symptomatic controller-naïve asthma patients, and in patients on inhaled corticosteroid (ICS) therapy. Uses: Bi671800 is used to treat patients with asthma. Synonyms: AP-761; AP 761; AP761; 5-Pyrimidineacetic acid, 4, 6-bis (dimethylamino) -2-[[4-[[4- (trifluoromethyl) benzoyl]amino]phenyl]methyl]-; 2- (4, 6-Bis (dimethylamino) -2- (4- (4- (trifluoromethyl) benzamido) benzyl) pyrimidin-5-yl) acetic acid; BI-671800; BI 671800; BI671800. Grades: >98%. CAS No. 1093108-50-9. Molecular formula: C25H26F3N5O3. Mole weight: 501.51. | |
| Bi-6c9 | BI-6C9 is a highly specific BH3 interacting domain (Bid) inhibitor, which prevents mitochondrial outer membrane potential (MOMP) and mitochondrial fission, and protects the cells from mitochondrial apoptosis inducing factor (AIF) release and caspase-independent cell death in neurons. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BI-6C9, N-[4-(4-aminophenyl)sulfanylphenyl]-4-[(4-methoxyphenyl)sulfonylamino]butanamide, N-[4-[(4-Aminophenyl)thio]phenyl]-4-[[(4-methoxyphenyl)sulfonyl]amino]-Butanamide, 791835-21-7, AGN-PC-00BBZS, SureCN3088138, B0186_SIGMA, AC1Q4C26, CTK8E8904, NCGC00165738-01. Product Category: Inhibitors. Appearance: Solid. CAS No. 791835-21-7. Molecular formula: C23H25N3O4S2. Mole weight: 471.59. Purity: 0.96. IUPACName: N-[4-(4-aminophenyl)sulfanylphenyl]-4-[(4-methoxyphenyl)sulfonylamino]butanamide. Canonical SMILES: COC1=CC=C(C=C1)S(=O)(=O)NCCCC(=O)NC2=CC=C(C=C2)SC3=CC=C(C=C3)N. Density: 1.368g/cm³. Product ID: ACM791835217. Alfa Chemistry ISO 9001:2015 Certified. | |
| BI-6C9 | BI-6C9 ( N-[4-[(4-Aminophenyl)thio]phenyl]-4-[[(4-methoxyphenyl)sulfonyl]amino]-Butanamide) is a tBid inhibitor that possesses antiapoptotic properties. Bid plays an essential role in matrine-induced AIF translocation. BI-6C9 also blocked matrine-induced AIF translocation detected by confocal microscopy. Bid inhibitor BI-6C9 was applied to confirm the essential role of Bid in cell death induced by matrine. Synonyms: N-[4-[(4-aminophenyl)thio]phenyl]-4-[[(4-methoxyphenyl)sulfonyl]amino]-butanamide. Grades: ≥98%. CAS No. 791835-21-7. Molecular formula: C23H25N3O4S2. Mole weight: 471.6. | |
| BI-7273 | BI-7273 is a potent BRD9 bromodomain inhibitor (Ki = 15.4 nM; IC50=19 nM). BI-7273 structurally related BRD7 bromodomain (IC50 = 117 nM) without effect against the BRD2 and BRD4 bromodomain or a panel of kinases. BI-7273 has potential for use in treating acute myeloid leukemia according to a study in vitro (EC50 = 1.4 μM). Uses: A potent brd9 bromodomain inhibitor for the treatment of leukemia. Synonyms: 4-{4-[(dimethylamino)methyl]-2,6-dimethoxyphenyl}-2-methyl-1,2-dihydro-2,7-naphthyridin-1-one; 4-(4-((Dimethylamino)methyl)-3,5-dimethoxyphenyl)-2-methyl-2,7-naphthyridin-1(2H)-one; 2,7-Naphthyridin-1(2H)-one, 4-[4-[(dimethylamino)methyl]-3,5-dimethoxyphenyl]-2-methyl-; BI7273; BI 7273. Grades: >98%. CAS No. 1883429-21-7. Molecular formula: C20H23N3O3. Mole weight: 353.41. | |
| BI 78D3 | BI 78D3. Group: Biochemicals. Grades: Purified. CAS No. 883065-90-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BI 78D3 | BI 78D3 is a competitive c-Jun N-terminal kinase (JNK) inhibitor (IC50 = 280 nM) with > 100 fold selectivity over p38α and no effect on mTOR and PI-3K. BI 78D3 inhibits JNK interacting protein 1 (JIP1) binding to JNK (IC50 = 500 nM) and prevents JNK substrate phosphorylation. It blocks JNK-dependent Con A-induced liver damage and also restores insulin sensitivity in a mouse model of type II diabetes. Synonyms: JNK Inhibitor X; BI-78D3; BI78D3; BI 78D3; 4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2,4-dihydro-5-[(5-nitro-2-thiazolyl)thio]-3H-1,2,4-triazol-3-one. Grades: ≥99% by HPLC. CAS No. 883065-90-5. Molecular formula: C13H9N5O5S2. Mole weight: 379.37. | |
| BI-847325 | BI-847325 is an orally available dual inhibitor of mitogen-activated protein kinase kinase (MEK) and Aurora kinases, with potential antineoplastic activity. Upon oral administration, MEK/Aurora kinase inhibitor BI 847325 selectively binds to and inhibits the activity of MEK, which both prevents the activation of MEK-dependent effector proteins and inhibits growth factor-mediated cell signaling. BI 847325 also binds to and inhibits the activity of the Aurora kinases A, B and C which may disrupt the assembly of the mitotic spindle apparatus, prevent chromosome segregation, and inhibit both cellular division and proliferation in Aurora kinase-overexpressing tumor cells. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BI-847325; BI 847325; BI847325. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1207293-36-4. Molecular formula: C29H28N4O2. Mole weight: 464.57. Purity: >98%. IUPACName: (Z)-3-(3-((4-((dimethylamino)methyl)phenylamino)(phenyl)methylene)-2-oxoindolin-6-yl)-N-ethylpropiolamide. Canonical SMILES: O=C(NCC)C#CC1=CC(NC/2=O)=C(C=C1)C2=C(NC3=CC=C(CN(C)C)C=C3)/C4=CC=CC=C4. Product ID: ACM1207293364-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| BI-847325 | BI-847325 is an orally bioavailable, and selective dual MEK/Aurora kinase inhibitor with IC50 of 3 nM, 25 nM, 15 nM, 25 nM, and 4 nM for Xenopus laevis Aurora B, human Aurora A and Aurora C, as well as human MEK1 and MEK2, respectively. Synonyms: BI-847325; BI 847325; BI847325. Grades: 98%. CAS No. 1207293-36-4. Molecular formula: C29H28N4O2. Mole weight: 464.56. | |
| BI-882370 | BI-882370 is a highly potent, selective, orally active RAF inhibitor with IC50 of 0.4, 0.8 and 0.6 nM for BRAF V600E, BRAF WT and CRAF, respectively. BI-882370 is a potent and selective RAF inhibitor uniquely binding to the DFG-out conformation, whereas marketed BRAF inhibitors occupy the DFG-in conformation. BI-882370 inhibits proliferation of human BRAF-mutant melanoma cells with 100× higher potency (1-10 nmol/L) than vemurafenib. BI-882370 may provide an improved therapeutic window, enabling more pronounced and longer-lasting pathway suppression and thus resulting in improved efficacy. Synonyms: BI882370; BI 882370. Grades: ≥95%. CAS No. 1392429-79-6. Molecular formula: C28H33F2N7O2S. Mole weight: 569.7. | |
| BI 9321 | BI 9321 is a nuclear receptor-binding SET domain (NSD) 3 antagonist with IC50 of 1.2 μM. It is also selectively binds the PWWP1 domain of NSD3 with Kd of 166 nM. BI 9321 antagonizes the interaction of H3 with NSD3-PWWP1 in U2OS cells. High selectivity of BI-9321 was confirmed using in vitro assays and quantitative chemical proteomics. Cellular target engagement was confirmed with FRAP (Fluorescence Recovery After Photobleaching) and BRET (Bioluminescence Resonance Energy Transfer) at 1 μM. Synonyms: (4-(5-(7-Fluoroquinolin-4-yl)-1-methyl-1H-imidazol-4-yl)-3,5-dimethylphenyl)methanamine trihydrochloride. Grades: ≥98%. Molecular formula: C22H21FN4·3HCl. Mole weight: 469.81. | |
| BI-9564 | BI-9564 is a potent and selective inhibitor of BRD9 and BRD7 bromodomains (Kds = 14.1 and 239 nM; IC50s = 75 nM and 3.4 μM, respectively), with selectivity for BRD9/7 over 48 other bromodomains, 324 kinases and 55 GPCRs. Synonyms: 4-(4-((dimethylamino)methyl)-2,5-dimethoxyphenyl)-2-methyl-2,7-naphthyridin-1(2H)-one; BI-9564; BI 9564; BI9564. CAS No. 1883429-22-8. Molecular formula: C20H23N3O3. Mole weight: 353.42. | |
| BI 99179 | BI 99179 is a potent and selective type I fatty acid synthase ( FAS ) inhibitor with an IC 50 of 79 nM. BI 99179 is a tool compound suitable for the in vivo validation of FAS as a target for lipid metabolism related diseases. BI 99179 exhibits significant exposure (both peripheral and central) upon oral administration in rats [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1291779-76-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16100. | |
| BIA 10-2474 | BIA 10-2474 is an inhibitor of fatty acid amide hydrolase ( FAAH ) with IC 50 values of 50 to 70mg/kg in various rat brain regions. Uses: Scientific research. Group: Signaling pathways. CAS No. 1233855-46-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19740. | |
| BIA10-2474 | This active molecular is a reversible FAAH (fatty acid amide hydrolase) inhibitor that increases levels of the neurotransmitter anandamide in the central nervous system and in peripheral tissues (except the brain and spinal cord) under the development of Bial-Portela & Ca. SA. BIA 10-2474 can interact with the human endocannabinoid system and was inpplicated in the treatment of a range of different medical conditions including anxiety, Parkinson's disease, chronic pain of multiple sclerosis, cancer, hypertension and obesity. Clinical trial with BIA 10-2474 was on-going. However, severe adverse events occurred in January 2016 affecting 5 patients, including leading to the death of one. Uses: Neurological disorders; pain; psychiatric disorders. Synonyms: BIA 10-2474; BIA-10-2474; BIA10-2474; N-cyclohexyl-N-methyl-4-(1-oxidopyridin-1-ium-3-yl)imidazole-1-carboxamide;UNII-5AP1ZW859M; SCHEMBL427970; 5AP1ZW859M; GTPL9001; DOWVMJFBDGWVML-UHFFFAOYSA-N. Grades: 98%. CAS No. 1233855-46-3. Molecular formula: C16H20N4O2. Mole weight: 300.36. | |
| Biacangelicol (Byakangelicol) | Biacangelicol (Byakangelicol). Group: Biochemicals. Alternative Names: Biacangelicol. Grades: Plant Grade. CAS No. 26091-79-2. Pack Sizes: 20mg. Molecular Formula: C17H16O6, Molecular Weight: 316.305. US Biological Life Sciences. | Worldwide |
| Biadamantylidene | Biadamantylidene. Group: Biochemicals. Grades: Highly Purified. CAS No. 30541-56-1. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C20H28. US Biological Life Sciences. | Worldwide |
| Bialamicol hydrochloride | Bialomicol is a synthetic bio-active chemical. Uses: A synthetic bio-active chemical. Synonyms: Bialamicol Hydrochloride; Bialamicol hydrochloride [USAN]; CAM 807; CAM-807; Camoform hydrochloride; CI 301; CI301; CI-301; NSC 6386;PAA 701 dihydrochloride; PAA-701; PAA701 dihydrochloride; SN 6771 dihydrochloride; UNII-VIQ3X36S8C;2-(diethylaminomethyl)-4-[3-(diethylaminomethyl)-4-hydroxy-5-prop-2-enylphenyl]-6-prop-2-enylphenol;dihydrochloride. Grades: ≥98%. CAS No. 3624-96-2. Molecular formula: C28H42Cl2N2O2. Mole weight: 509.556. | |
| Bialaphos | 10mg Pack Size. Group: Biochemicals, Building Blocks, Organics, Peptide Reagents, Research Organics & Inorganics. Formula: C11H22N3O6P. CAS No. 35597-43-4. Prepack ID 14973551-10mg. Molecular Weight 323.28. See USA prepack pricing. |  |
| Bialaphos | Bialaphos is a phosphorus-containing tripeptide produced by Streptomyces viridochromogenes and Str. hygroscopicus. It has anti-bacterial, anti-fungal activity, and has herbicidal effect. Synonyms: Bilanafos; Herby; Antibiotic SF 1293. Grades: >98%. CAS No. 35597-43-4. Molecular formula: C11H22N3O6P. Mole weight: 323.28. | |
| Bialaphos sodium | Bialaphos (SF-1293) sodium, an antibiotic , is an effective herbicide is a metabolite of Streptomyces hygroscopicus [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SF-1293 sodium. CAS No. 71048-99-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-122494A. | |
| Bialaphos sodium | A freely soluble herbicide synthesized by streptomyces hygroscopicus and streptomyces viridochromeogenes. CAS No. 71048-99-2. Molecular formula: C11H21N3NaO6P. Mole weight: 345.27. | |
| Bialaphos Sodium Salt | Bialaphos Sodium Salt is a tripeptide antibiotic that is employed in the transformation experiments of many species of plants that make use of the bar gene for selection. It is more effective than glufosinate in corn. In wheat, bialaphos was the most reliable selection criteria used to identify bar transformed plants. Group: Biochemicals. Alternative Names: (2S) -2-Amino-4- (hydroxy methyl phosphinyl) butanoyl-L-alanyl-L-alanine Monosodium Salt; γ - (Hydroxy methyl phosphinyl) -L- α -aminobutyryl-L-alanyl-L-alanine Monosodium Salt; Bilanafos Sodium Salt; Herbi-Ace; Herbie; MW 801; SF 1293. Grades: Highly Purified. CAS No. 71048-99-2. Pack Sizes: 25mg, 50mg, 100mg. Molecular Formula: C??H??N?NaO?P, Molecular Weight: 345.26. US Biological Life Sciences. | Worldwide |
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