A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
BIM 23052. Group: Biochemicals. Grades: Purified. CAS No. 133073-82-2. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
BIM 23056
BIM 23056 is a somatostatin receptor ligand (Ki = 142, > 1000, 10.8, 16.6 and 5.7 nM for human cloned sst1 - 5 receptors respectively). It acts as an antagonist on SRIF14-induced [35S]-GTPγS binding at sst3 and sst5 receptors (PKB = 6.33 and 5.84, respectively). Synonyms: IM 23056; IM23056; IM-23056. Grades: >98%. CAS No. 150155-61-6. Molecular formula: C71H81N11O9. Mole weight: 1232.49.
BIM 23056. Group: Biochemicals. Grades: Purified. CAS No. 150155-61-6. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
BIM 23056 acetate
BIM 23056 acetate is a potent and surmountable human recombinant somatostatin receptor antagonist (Ki = 142, >1000, 10.8, 16.6 and 5.7 nM for human cloned sst1-5 receptors, respectively). It acts as an antagonist on SRIF14-induced [35S]-GTPγS binding at sst3 and sst5 receptors (PKB = 6.33 and 5.84, respectively). Synonyms: H-D-Phe-Phe-Tyr-D-Trp-Lys-Val-Phe-D-2Nal-NH2.CH3CO2H; D-phenylalanyl-L-phenylalanyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-phenylalanyl-3-(2-naphthyl)-D-alaninamide acetic acid. Grades: ≥95%. CAS No. 2763584-06-9. Molecular formula: C73H85N11O11. Mole weight: 1292.52.
BIM 23127
BIM 23127. Group: Biochemicals. Grades: Purified. CAS No. 160161-61-5. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
BIM-23627
BIM 23627 is a somatostatin antagonist with IC50s of 2757, 6.4, 44, 423 and 86.5 nM for five human somatostatin receptor subtypes HSST1, HSST2, HSST3, HSST4 and HSST5, respectively. It selectively binds to human somatostatin receptor subtype 2 (HSST2) with high affinity, but is completely inactive in stimulating intracellular calcium mobilization. Synonyms: H-p-Chloro-Phe-D-Cys-β-(2-pyridyl)-Ala-Trp-Lys-Val-Cys-2-Nal-NH2 (Disulfide bridge: Cys2 and Cys7). Grades: ≥90%. CAS No. 429619-37-4. Molecular formula: C58H69ClN12O8S2. Mole weight: 1161.85.
BIM-46050
BIM-46050 is a novel and potent inhibitor of human farnesyltransferase. Synonyms: BIM46050; BIM 46050; (S)-2-((R)-3-((2S,3S)-2-(((R)-2-amino-3-mercaptopropyl)amino)-3-methylpentyl)-5,5-dimethylthiazolidine-4-carboxamido)-4-(methylthio)butanoic acid. Grades: >98%. CAS No. 201487-52-7. Molecular formula: C14H12N6O. Mole weight: 480.75.
BIM-46068
BIM-46068 is a novel and potent inhibitor of human farnesyltransferase. Synonyms: BIM 46068; BIM46068; (S)-methyl 2-((R)-3-((2S,3S)-2-(((R)-2-amino-3-mercaptopropyl)amino)-3-methylpentyl)-5,5-dimethylthiazolidine-4-carboxamido)-4-(methylthio)butanoate. Grades: >98%. CAS No. 201487-53-8. Molecular formula: C17H28ClNO2. Mole weight: 494.77.
BIM5078
Hepatocyte nuclear factor (HNF)4α is a key regulator of gene expression in cell types playing an important role in metabolic homeostasis, such as hepatocytes, enterocytes, as well as pancreatic β cells. BIM5078 is a potent hepatocyte nuclear factor 4a (HNF4a) antagonist that directly binds to ligand-binding pocket of HNF4α with an EC50 value of 11.9 nM and modulates the expression of known HNF4a target genes. The EC50 of BIM5078 was calculated to be 11.9 nM and further analyses of the data using the Hill equation showed that the Hill coefficient for BIM5078 was 0.9, consistent with a single binding complex between BIM5078 and HNF4&alpha. Grades: ≥98%. CAS No. 337506-43-1. Molecular formula: C14H10ClN3O4S. Mole weight: 351.8.
Bimagrumab (Anti-ACVR2B Reference Antibody) is a human monoclonal antibody that blocks activin type II receptor (ActRII) , with K D s of 1.7 pM and 434 pM for human ActRIIB and ActRIIA , respectively. Bimagrumab can be used for the research of pathological muscle loss and weakness [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-ACVR2B Reference Antibody; BYM338. CAS No. 1356922-05-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99355.
Bimatoprost
Bimatoprost is an antiglaucoma agent. Bimatoprost is an synthetic prostamide; structurally related to prostaglandin F2α. Group: Biochemicals. Alternative Names: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-ethyl-5-heptenamide; AGN-192024; Lumigan; Prostamide. Grades: Highly Purified. CAS No. 155206-00-1. Pack Sizes: 1mg. US Biological Life Sciences.
Bimatoprost is a prostaglandin analog that reduces intraocular pressure by regulating scleral and trabecular outflow. Bimatoprost is used in the study of open-angle glaucoma, ocular hypertension, and other forms of glaucoma. Topical application of bimatoprost induces fat atrophy and causes a deepening of the eyelid sulcus [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AGN 192024. CAS No. 155206-00-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0191.
Bimatoprost
Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Uses: For research used only. Synonyms: AGN 192024; AGN192024; AGN-192024; Bimatoprost; Lumigan; Latisse; Bimatoprostum; Lumigan. Grades: >98%. CAS No. 155206-00-1. Molecular formula: C25H37NO4. Mole weight: 415.57.
Bimatoprost
25mg Pack Size. Group: Building Blocks, Organics, Research Organics & Inorganics. Formula: C25H37NO4. CAS No. 155206-00-1. Prepack ID 15060220-25mg. Molecular Weight 415.57. See USA prepack pricing.
Bimatoprost 13,14-Epoxide
Bimatoprost 13,14-Epoxide is one of bimatoprost impurities. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Synonyms: 17-Phenyl-18,19,20-trinor-PGF2α 13,14-Epoxide; Bimatoprost Impurity 2 (Mixture of Diastereomers). Molecular formula: C25H37NO5. Mole weight: 431.56.
Bimatoprost 13,14-Epoxide
Bimatoprost 13,14-Epoxide is the impurity of Bimatoprost (B386800), which is an antiglaucoma agent. Bimatoprost is an synthetic prostamide; structurally related to prostaglandin F2α. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C25H37NO5, Molecular Weight: 431.56. US Biological Life Sciences.
Worldwide
Bimatoprost Acid
Bimatoprost Acid is an impurity of the antiglaucoma agent Bimatoprost. It is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-5-heptenoic Acid; 17-Phenyl-18,19,20-trinor-PGF2α; PhXA 70; (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-pentenyl]cyclopentyl]-5-heptenoic Aci. Grades: > 95%. CAS No. 38344-08-0. Molecular formula: C23H32O5. Mole weight: 388.51.
Bimatoprost Acid Methyl Ester
Bimatoprost Acid Methyl Ester is an impurity of the antiglaucoma agent Bimatoprost. Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-5-heptenoic Acid Methyl Ester; 17-Phenyl-18,19,20-trinor-PGF2α Methyl Ester. Grades: > 95%. CAS No. 38315-47-8. Molecular formula: C24H34O5. Mole weight: 402.54.
Bimatoprost Impurity 10
Bimatoprost Impurity 10 is one of bimatoprost impurities. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Molecular formula: C25H43NO6. Mole weight: 453.61.
Bimatoprost Impurity 11
Bimatoprost Impurity 11 is one of bimatoprost impurities. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Molecular formula: C25H41NO6. Mole weight: 451.59.
Bimatoprost Impurity 13
Bimatoprost Impurity 13 is one of bimatoprost impurities. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Molecular formula: C35H51NO6. Mole weight: 581.78.
Bimatoprost Impurity 14
Bimatoprost Impurity 14 is one of bimatoprost impurities. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Molecular formula: C35H53NO6. Mole weight: 583.80.
Bimatoprost Impurity 3
Bimatoprost Impurity 3 is one of bimatoprost impurities. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Molecular formula: C23H33NO4. Mole weight: 387.51.
Bimatoprost Impurity 9
Bimatoprost Impurity 9 is one of bimatoprost impurities. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Molecular formula: C34H63NO6Si. Mole weight: 609.95.
Bim BH3
Bim BH3 is a biological active peptide. (This Bim peptide belongs to the pro-apoptotic Bcl-2 family of proteins.). Uses: Scientific research. Group: Peptides. CAS No. 505070-06-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P1527.
BIM (Biotin)
BIM (Biotin). Group: Biochemicals. Grades: Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Bi-Mc-VC-PAB-MMAE
Bi-Mc-VC-PAB-MMAE consists ADCs linker (Bi-Mc-Val-Cit-PAB) and potent tubulin inhibitor (MMAE, HY-15162). Bi-Mc-VC-PAB-MMAE is a drug-linker conjugate for ADC. Uses: Scientific research. Group: Signaling pathways. CAS No. 1620837-70-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-141833.
Bimekizumab
Bimekizumab (Anti-Human IL17A/IL-17F Recombinant Antibody) is a humanised monoclonal antibody, can selectively neutralises IL-17A and IL-17F. Both of them are pro-osteogenic with respect to human periosteum-derived cell (hPDC) differentiation. Thus Bimekizumab blocks the inflammation-driven osteogenic differentiation [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human IL17A/IL-17F Recombinant Antibody. CAS No. 1418205-77-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99280.
Bim-IN-1
Bim-IN-1 is a potent Bim expression inhibitor. Bim-IN-1 reduces Bim expression levels and has little inhibitory effect upon protein kinase A activity and minimal toxicity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2909483-36-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115930.
Bimiralisib
Bimiralisib (PQR309) is a potent, brain-penetrant, orally bioavailable, pan-class I PI3K/mTOR inhibitor with IC50s of 33 nM, 451 nM, 661 nM, 708 nM and 89 nM for PI3K?, PI3K?, PI3K?, PI3K? and mTOR, respectively. Bimiralisib is an mTORC1 and mTORC2 inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PQR309. CAS No. 1225037-39-7. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12868.
Bimiralisib free base
Bimiralisib, also known as PQR309, is an orally bioavailable pan inhibitor of phosphoinositide-3-kinases (PI3K) and inhibitor of the mammalian target of rapamycin (mTOR), with potential antineoplastic activity. PI3K/mTOR kinase inhibitor PQR309 inhibits the PI3K kinase isoforms alpha, beta, gamma and delta and, to a lesser extent, mTOR kinase, which may result in tumor cell apoptosis and growth inhibition in cells overexpressing PI3K/mTOR. Activation of the PI3K/mTOR pathway promotes cell growth, survival, and resistance to both chemotherapy and radiotherapy. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PQR309; PQR-309; PQR309; Bimiralisib free base. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1225037-39-7. Molecular formula: C17H20F3N7O2. Mole weight: 411.39. Purity: >98%. IUPACName: 5-(4,6-dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine. Canonical SMILES: NC1=NC=C(C2=NC(N3CCOCC3)=NC(N4CCOCC4)=N2)C(C(F)(F)F)=C1. Product ID: ACM1225037397. Alfa Chemistry ISO 9001:2015 Certified.
Bimoclomol
Bimoclomol is a heat shock protein (HSP) coinducer that exhibits cytoprotective effects. It can be used in the treatment of cardiovascular diseases. Synonyms: (3Z)-N-(2-hydroxy-3-piperidin-1-ylpropoxy)pyridine-3-carboximidoyl chloride; bimoclomol; bimoclomol, maleate (1:1). CAS No. 130493-03-7. Molecular formula: C14H20ClN3O2. Mole weight: 297.78.
Bimoclomol
Bimoclomol is a heat shock protein (HSP) coinducer, used for treatment of cardiovascular diseases. Uses: Scientific research. Group: Signaling pathways. CAS No. 130493-03-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00398.
Bimolane
Bimolane is a topoisomerase II inhibitor. It has been widely used as an anti-neoplastic agent and for the treatment of psoriasis in China. Bimolane is also a leukemogenic agent and is thought to exert its effects through the inhibition of topoisomerase II. Uses: Psoriasis. Synonyms: Bimolane;4,4'-Ethylenebis[1-(morpholinomethyl)-2,6-piperazinedione];AT-1727; AT1727; AT 1727; CCRIS 7574; CCRIS7574; CCRIS-7574; NSC 351358. Grades: 98%. CAS No. 74550-97-3. Molecular formula: C20H32N6O6. Mole weight: 452.51.
Bimolane
Bimolane (AT-1727), a human topoisomerase II inhibitor, can be used as an anti-neoplastic agent and for the research of psoriasis. Bimolane shows leukemogenic activity and induces multiple types of chromosomal aberrations in human lymphocytes. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Bimolane;4,4'-Ethylenebis[1-(morpholinomethyl)-2,6-piperazinedione];AT-1727. Product Category: Inhibitors. CAS No. 74550-97-3. Molecular formula: C20H32N6O6. Product ID: ACM74550973. Alfa Chemistry ISO 9001:2015 Certified. Categories: Bimala Nepali.
Bimosiamose
Bimosiamose (TBC-1269) is a nonoligosaccharide pan-selectin antagonist with IC50s of 88 ?M, 20 ?M, and 86 ?M for E-selectin, P-selectin, and L-selectin, respectively. Bimosiamose has anti-inflammatory effects[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TBC-1269. CAS No. 187269-40-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106139.
BIMU 8
BIMU 8 is a potent and selective 5-HT4 receptor full agonist (KD = 77 nM and EC50 = 18 nM for wild type 5-HT4 receptors). Synonyms: BIMU 8; BIMU8; BIMU-8; 2,3-Dihydro-N-[(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]-3-(1-methylethyl)-2-oxo-1H-benzimidazole-1-carboxamide hydrochloride; N-[(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-3-propan-2-ylbenzimidazole-1-carboxamide hydrochloride. Grades: ≥98% by HPLC. CAS No. 134296-40-5. Molecular formula: C19H26N4O2.HCl. Mole weight: 378.9.
BIMU 8
BIMU 8. Group: Biochemicals. Grades: Purified. CAS No. 134296-40-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
BIMU 8
BIMU 8 is a potent and selective 5-HT4 agonist with EC 50 s of 18 nM, 77 nM, and 540 nM for wild type 5HT4 receptor , T3.36A , and W6.48A mutant 5-HT4 receptors [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 134296-40-5. Pack Sizes: 1 mg. Product ID: HY-110094.
Bin1b is a beta-defensins-like molecule originally isolated from the rat epididymis.
BINA
BINA. Group: Biochemicals. Grades: Purified. CAS No. 866823-73-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
BINA
BINA is a selective positive allosteric modulator of mGlu2 (EC50 = 33.2 nM in CHO cells expressing human mGlu2) with no effect on glutamate-induced activation of other mGlu receptor subtypes. BINA exhibits antipsychotic and anxiolytic properties in mice. Synonyms: 3'-[[(2-Cyclopentyl-2,3-dihydro-6,7-dimethyl-1-oxo-1H-inden-5-yl)oxy]methyl]-[1,1'-biphenyl]-4-carboxylic acid; Biphenylindanone A; Biphenyl-indanone A. Grades: ≥98% by HPLC. CAS No. 866823-73-6. Molecular formula: C30H30O4. Mole weight: 454.56.
BINA (Biphenyl-indanone A)
A selective positive allosteric modulator for mGlu receptor subtype 2 (EC50 = 33.2nM in CHO cells expressing human mGlu2). No effect on other mGlu receptor subtypes. Exhibits antipsychotic and anxiolytic properties in mice. Group: Biochemicals. Grades: Highly Purified. CAS No. 866823-73-6. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
BINAP, mono-oxide
BINAP, mono-oxide (CAS# 204862-91-9 ) is a useful research chemical. Grades: 95 %. CAS No. 204862-91-9. Molecular formula: C44H32OP2. Mole weight: 638.69.
Bindarit shows anti-inflammatory activity due to a selective inhibition of a subfamily of inflammatory chemokines. Bindarit is a also protein antidenaturant agent. Bindarit modulates the NFkB pathway and has been shown to reduce secondary phase of adjuvant arthritis in rats. Group: Biochemicals. Alternative Names: 2-Methyl-2-[[1-(phenylmethyl)-1H-indazol-3-yl]methoxy]propanoic Acid; 2-[(1-Benzyl-1H-indazol-3-yl)methoxy]-2-methylpropanoic Acid; 2-[(1-Benzyl-1H-indazol-3-yl)methoxy]-2-methylpropionic Acid; AF 2838. Grades: Highly Purified. CAS No. 130641-38-2. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Bindarit
Bindarit (AF2838) is a selective inhibitor of the monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7, and MCP-2/CCL8, and no effect on other CC and CXC chemokines such as MIP-1?/CCL3, MIP-1?/CCL4, MIP-3/CCL23. Bindarit also has anti-inflammatory activity[1]. Uses: Scientific research. Group: Natural products. Alternative Names: AF2838. CAS No. 130641-38-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0498.
Bindarit
Bindarit treatment inhibits the release of MCP-1 from IL-1 stimulated osteoblast cell line Saos-2. Synonyms: Bindarit; AF-2838; AF2838; AF 2838. Grades: >98%. CAS No. 130641-38-2. Molecular formula: C19H20N2O3. Mole weight: 324.37.
Bindarit-d5
Bindarit-d5. Group: Biochemicals. Alternative Names: 2-Methyl-2-[[1-(phenylmethyl)-1H-indazol-3-yl]methoxy]propanoic Acid-d5; 2-[(1-Benzyl-1H-indazol-3-yl)methoxy]-2-methylpropanoic Acid-d5; 2-[(1-Benzyl-1H-indazol-3-yl)methoxy]-2-methylpropionic Acid-d5; AF 2838-d5. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C19H15D5N2O3, Molecular Weight: 329.4. US Biological Life Sciences.
Binodenoson is a pharmacologic stress agent specific to the only adenosine receptor necessary for increased cardiac blood flow, the A2A receptor agonist. It is used to diagnose coronary artery disease. Uses: Purinergic p1 receptor agonists. Synonyms: 2- (Cyclohexylmethylidenehydrazino) adenosine; 2-(2-(Cyclohexylmethylene)diazanyl)-9-beta-D-ribofuranosyl-9H-purin-6-amine; (2R,3R,4S,5R)-2-(6-Amino-2-(2-(cyclohexylmethylene)hydrazinyl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. Grades: ≥95%. CAS No. 144348-08-3. Molecular formula: C17H25N7O4. Mole weight: 391.42.
Bintrafusp alfa
Bintrafusp alfa (M 7824) is a first-in-class bifunctional fusion protein composed of the extracellular domain of TGF-βRII fused to a human IgG1 mAb blocking programmed cell death ligand. Bintrafusp alfa can be used for the research of cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: M7824; MSB0011359C. CAS No. 1918149-01-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99480.
Binucleine 2 is an inhibitor of cytokinesis function of the ARK-2 pathway. It is also an isoform-specific and ATP-competitive inhibitor of Drosophila Aurora B kinase (Ki = 0.36 μM), a kinase involved in cell division. It is specific for Drosophila Aurora B kinase, inhibiting it in a dose-dependent manner, with minimal inhibition of human or X. laevis Aurora B kinases at concentrations up to 100 μM. Binucleine 2 induces mitotic and cytokinesis defects in Drosophila Kc167 cells. Synonyms: Binucleine 2; 220088-42-6; N'-[2-(3-chloro-4-fluorophenyl)-4-cyanopyrazol-3-yl]-N,N-dimethylmethanimidamide; N'-(1-(3-Chloro-4-fluorophenyl)-4-cyano-1H-pyrazol-5-yl)-N,N-dimethyliminoformamide; HMS546I06; Probes1_000319; Probes2_000073; CHEMBL1598812; DTXSID90430554; Binucleine 2, >=97% (HPLC); CCG-41865; MFCD00177827; AKOS040755467; NCGC00165742-01; J-014418; SR-01000631912-1; N'-(1-(3-Chloro-4-fluorophenyl)-4-cyano-1H-pyrazol-5-yl)-N,N-dimethylformimidamide. Grades: ≥98%. CAS No. 220088-42-6. Molecular formula: C13H11ClFN5. Mole weight: 291.7.
BIO
BIO. Group: Biochemicals. Grades: Purified. CAS No. 667463-62-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
BIO
BIO is a potent and reversible inhibitor of GSK-3 with IC50 of 5 nM for GSK-3α/&beta. BIO enhances reprogramming of mouse fibroblasts, neural stem cells, and thymocytes to induced pluripotent stem (iPS) cells. It also promotes differentiation of cardiomyocytes from human ES and iPS cells. Synonyms: GSK-3 Inhibitor IX; 6-bromoindirubin-3-oxime; 6-bromo-3-(3-nitroso-1H-indol-2-yl)-1H-indol-2-ol. Grades: >98%. CAS No. 667463-62-9. Molecular formula: C16H10BrN3O2. Mole weight: 356.17.
BIO-11006 is a myristoylated alanine-rich C kinase substrate (MARCKS) inhibitor, similar to MANS peptides. Synonyms: BIO-11006 peptide; L-Lysine, N-acetylglycyl-L-alanyl-L-glutaminyl-L-phenylalanyl-L-seryl-L-lysyl-L-threonyl-L-alanyl-L-alanyl-; N-Acetylglycyl-L-alanyl-L-glutaminyl-L-phenylalanyl-L-seryl-L-lysyl-L-threonyl-L-alanyl-L-alanyl-L-lysine; BIO 11006; BIO11006; Ac-Gly-Ala-Gln-Phe-Ser-Lys-Thr-Ala-Ala-Lys-OH. Grades: ≥95%. CAS No. 901117-03-1. Molecular formula: C46H75N13O15. Mole weight: 1050.17.
BIO 1211
BIO 1211 is a selective and high affinity integrin α4β1 (Very Late Antigen 4; VLA-4) inhibitor with 200-fold selectivity for the activated form of α4β1 (KD = 70 pM; IC50=0.004 μM). Synonyms: BIO-1211; BIO1211. Grades: >98%. CAS No. 187735-94-0. Molecular formula: C36H48N6O9. Mole weight: 708.8.
BIO 1211
BIO 1211. Group: Biochemicals. Grades: Purified. CAS No. 187735-94-0. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
BIO (2Z, 3E)-6-Bromo-3-(hydroxyimino)-[2,3-biindolinylidene]-2-one
A potent, selective, reversible and ATP-competitive inhibitor of GSK-3α/ β (IC50 = 5nM). Under a feeder-free condition, BIO maintains embryonic stem cells (hESCs) in the undifferented state. Group: Biochemicals. Alternative Names: (2Z,3E)-6-Bromo-3-(hydroxyimino)-[2,3-biindolinylidene]-2-one. Grades: Highly Purified. CAS No. 667463-62-9. Pack Sizes: 1mg. US Biological Life Sciences.