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| Product | Description | |
|---|---|---|
| CID 11210285 hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| CID 1375606 | CID 1375606 is a surrogate agonist of orphan G protein-coupled receptor GPR27. Promotes recruitment of β-arrestin 2 to chimeric GPR27V2 and wild-type GPR27 in a firefly luciferase complementation assay (pEC50 values are 6.34 and 5.1, respectively). GPR27 is characterized by a high level of conservation among vertebrates and a predominant expression in the central nervous system. In addition, it has recently been linked to insulin secretion. Synonyms: 2,4-Dichloro-N-(phenylcarbamoyl)phenylbenzamide; 2,4-Dichloro-N-(4-(phenylcarbamoyl)phenyl)benzamide. Grades: ≥98% by HPLC. CAS No. 313493-80-0. Molecular formula: C20H14Cl2N2O2. Mole weight: 385.24. |  |
| CID 1375606 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CID16020046 | CID16020046 is a selective GPR55 inverse agonist. CID16020046 is a G protein-coupled receptor that is weakly activated by some cannabinoids at nM concentrations. CID16020046 has been shown to block GPR55-mediated endothelial wound healing and reverse LPI-inhibited platelet aggregation. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CID16020046; CID-16020046; CID 16020046. Product Category: Agonists. Appearance: Solid powder. CAS No. 834903-43-4. Molecular formula: C25H19N3O4. Mole weight: 425.44. Purity: >98%. IUPACName: 4-[4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1,4-dihydropyrrolo[3,4-d]pyrazol-5-yl]benzoic acid. Canonical SMILES: O=C(O)C1=CC=C(N(C2=O)C(C3=CC=CC(O)=C3)C4=C2NN=C4C5=CC=C(C)C=C5)C=C1. Product ID: ACM834903434. Alfa Chemistry ISO 9001:2015 Certified. |  |
| CID16020046 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CID 16020046 | CID 16020046 is a potent and selective GPR55 antagonist and inhibits GPR55 constitutive activity with an IC 50 of 0.15 μM. CID 16020046 inhibits GPR55-mediated Ca 2+ signaling and GPR55-mediated ERK1/2 phosphorylation. CID 16020046 reduces wound healing in endothelial cells and is involved in the regulation of platelet function [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 834903-43-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16697. |  |
| CID 16020046 | CID 16020046 is a potent and selective GPR55(LPI receptor) antagonist, which inhibitsGPR55 constitutive activity. It reduced LPI-induced wound healing in primary human lung microvascular endothelial cells and reversed LPI-inhibited platelet aggregation. Synonyms: CID16020046; CID-16020046; CID 16020046. Grades: >98%. CAS No. 834903-43-4. Molecular formula: C25H19N3O4. Mole weight: 425.44. | |
| CID 16020046 | CID 16020046. Group: Biochemicals. Grades: Purified. CAS No. 834903-43-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| CID 2011756 | CID 2011756. Group: Biochemicals. Grades: Purified. CAS No. 638156-11-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CID-2011756 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CID-2011756 | CID 2011756 is an ATP competitive PKD inhibitor, with an IC50 of 3.2 μM for PKD1 in cell free assay, and also shows cellular pan-PKD inhibitory activity against PKD2 and PKD3 (IC50, 0.6 and 0.7 μM, respectively). CID 2011756 also has antitumor activity. Synonyms: CID2011756; CID 2011756; CID-2011756. CAS No. 638156-11-3. Molecular formula: C22H21ClN2O3. Mole weight: 396.871. | |
| CID 2011756 (Pan Protein Kinase D (PKD) Inhibitor, Cell Permeable, 5- (3-Chlorophenyl) -N-[4- (4-morpholinylmethyl) phenyl]-2-furancarboxamide) | Protein kinase D (PKD) inhibitor (IC50 values are 0.6, 0.7 and 3.2um for PKD2, PKD3 and PKD1 respectively). Cell permeable (EC50=10um for PKD1 inhibition). ATP-competitive. Group: Biochemicals. Grades: Highly Purified. CAS No. 638156-11-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| CID-25014542 | CID-25014542 is a Raf kinase inhibitor. Synonyms: CID-25014542; CID25014542; CID 25014542. 5-Chloro-3-(3,5-dibromo-4-hydroxybenzylidene)indolin-2-one; (3Z)-5-chloro-3-[(3,5-dibromo-4-hydroxyphenyl)methylidene]-1H-indol-2-one. CAS No. 220904-99-4. Molecular formula: C15H8Br2ClNO2. Mole weight: 429.492. | |
| CID 2745687 | CID 2745687 has been found to be a GPR35 antagonist and could probably be used in immune or gastrointestinal system regulation. Synonyms: CID 2745687; CID2745687; CID-2745687; 1- (2, 4-Difluorophenyl) -5- [ [2- [ [ (1, 1-dimethylehyl) amino] thioxomethyl] hydrazinylidene] methyl] -1H-pyrazole-4-carboxylic acid methyl ester. Grades: ≥98% by HPLC. CAS No. 264233-05-8. Molecular formula: C17H19F2N5O2S. Mole weight: 395.43. | |
| CID 2745687 | CID 2745687. Group: Biochemicals. Grades: Purified. CAS No. 264233-05-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CID 2818500 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CID-2818500 | CID-2818500 is an inhibitor of protein arginine methyltransferase 1 (PRMT1). It also inhibits histone H4 methylation by PRMT8, but not histone H3.1 methylation by CARM1 or Set7/9, when used at concentrations of 10 and 100 μM. Synonyms: α-Nitrostilbene; NSC 385; 1,1'-(1-nitro-1,2-ethenediyl)bis-benzene. Grades: ≥98%. CAS No. 1215-07-2. Molecular formula: C14H11NO2. Mole weight: 225.2. | |
| CID2858522 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CID 2858522 | CID 2858522. Group: Biochemicals. Grades: Purified. CAS No. 758679-97-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| CID-2858522 | CID-2858522 selectively inhibits the NF-κB pathway induced by PKC, operating downstream of PKC but upstream of IKKbeta, without inhibiting other NF-kappaB activation pathways. Synonyms: CID2858522; CID-2858522; CID 2858522; ML029; ML-029; ML 029. Grades: >98%. CAS No. 758679-97-9. Molecular formula: C28H39N3O3. Mole weight: 465.63. | |
| CID 2858522 (Selectively Inhibits PKC-induced NF-kB Activation, 1-[3,5-Bis(1,1-dimethylethyl)-4-hyd roxyphenyl]-2-[2-[(3-hydroxypropyl)amino]-5,6-dime thyl-1H-benzimidazol-1-yl]ethanone) | Selectively inhibits protein kinase C (PKC)-induced activation of the NF-kappaB pathway (IC50 < 0.1um for PMA-stimulated IL-8 production). Inhibits antigen receptor-stimulated NF-kappaB activation in chronic lymphocytic leukemia (CLL) B cells. Does not inhibit other NF-kappaB pathways, including that activated by tumor necrosis factor (TNF). Group: Biochemicals. Grades: Highly Purified. CAS No. 758679-97-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| CID44216842 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CID 5380390 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CID5721353 | CID5721353 is a B-Cell Lymphoma 6 Inhibitor (BCL6 inhibitor) that disrupts BCL6/corepressor complexes in vitro and in vivo, and was shown to bind the critical site within the BTB groove. Synonyms: 2-((5Z)-5-(5-Bromo-2-oxo-1H-indol-3-ylidene)-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl)butanedioic acid; CID5721353; CID-5721353; CID 5721353; BCL6 Inhibitor, 79-6. CAS No. 301356-95-6. Molecular formula: C15H9BrN2O6S2. Mole weight: 457.26. | |
| CID 5951923 | CID 5951923. Group: Biochemicals. Grades: Purified. CAS No. 749872-43-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CID 5951923 | CID 5951923 has been found to be a KLF-5 expression inhibitor and could exhibit selective activity against colon cancer cells. Synonyms: CID-5951923; CID 5951923; CID5951923; 2-[Methyl(tetrahydro-1,1-dioxido-3-thienyl)amino]-2-oxoethyl (E)-3-(3-nitrophenyl)prop-2-enoate. Grades: ≥97% by HPLC. CAS No. 749872-43-3. Molecular formula: C16H18N2O7S. Mole weight: 382.39. | |
| CID 5951923 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CID 697851 | CID 697851 is an AddAB and RecBCD inhibitor, with IC 50 s of 13 and 33 nM. CID 697851 can be used for antibacterial research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 312508-42-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-151221. | |
| CID755673 | ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| CID 755673 | CID 755673. Group: Biochemicals. Grades: Purified. CAS No. 521937-07-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| CID-755673 | CID-755673 is a selective protein kinase D (PKD) inhibitor. CID-755673 was identified from the National Institutes of Health small molecule repository library of 196,173 compounds. In cell-based assays, CID755673 blocked phorbol ester-induced endogenous PKD1 activation in LNCaP cells in a concentration-dependent manner. CID755673 inhibited prostate cancer cell proliferation, cell migration, and invasion. In summary, our findings indicate that CID755673 is a potent and selective PKD1 inhibitor with valuable pharmacological and cell biological potential. Synonyms: CID-755673; CID 755673; CID755673. Grades: 0.98. CAS No. 521937-07-5. Molecular formula: C12H11NO3. Mole weight: 217.224. | |
| CID-797718 | A novel protein kinase D inhibitor that causes potent arrest in prostate cancer cell growth and motility. Synonyms: CID 797718; CID-797718; CID797718. Grades: >98%. CAS No. 370586-05-3. Molecular formula: C12H11NO3. Mole weight: 217.22. | |
| Cider Vinegar, 3.8 L | Characteristic: Brown (cider vinegar) or colorless (white vinegar). Storage Code: Green; general chemical storage. Notes: Contains at least 4% acetic acid. Grades: chem-grade laboratory. CAS No. 64-19-7. Product ID: 898108. -- SOLD FOR EDUCATIONAL USE ONLY -- |  |
| C.I. Direct Blue 85 | C.I. Direct Blue 85. Uses: Designed for use in research and industrial production. Additional or Alternative Names: C.I. Direct Blue 85;Saturn Navy Blue LFG;Solophenyl Blue FGL;Cibafix Blue E-G;Direct Blue 137;Solophenyl Blue FGL 220;Direct Blue 85;Direct Blue 85. Product Category: Direct Dyes. CAS No. 61724-72-9. Purity: 0.96. Product ID: ACM61724729. Alfa Chemistry ISO 9001:2015 Certified. Categories: C.I. Direct Blue 15. | |
| C.I.Disperseblue106 | C.I.Disperseblue106. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Disperse Blue CR. Appearance: Dark blue powder. CAS No. 12223-01-7. Molecular formula: C14H17N5O3S. Mole weight: 335.38. Product ID: ACM12223017. Alfa Chemistry ISO 9001:2015 Certified. | |
| C.I. Disperse Blue A press cake | C.I. Disperse Blue A press cake. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Disperse Blue A. Appearance: Blue powder. CAS No. 88102-88-9. Molecular formula: C16H20N6O6S. Mole weight: 424.43. Product ID: ACM88102889. Alfa Chemistry ISO 9001:2015 Certified. | |
| Cidofovir | Cidofovir is inhibitory to CMV plaque formation even when added to the cells at 48 hr post infection with IC50 of 0.9 μg/mL for Davis and 1.6 μg/mL for AD-169 strains,respectively. Synonyms: Vistide; HPMPC; (S)-HPMPC; Cidofovir anhydrous; GS-504; GS 504; GS504; (S)-1-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine; (S)-(((1-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl)oxy)methyl)phosphonic acid. Grades: ≥98% by HPLC. CAS No. 113852-37-2. Molecular formula: C8H14N3O6P. Mole weight: 279.19. | |
| Cidofovir | 1-[(S)-3-hydroxy-2-(phosphonomethoxy)propyl]cytosine; (S)-HPMPC. CAS No. 113852-37-2. Product ID: 8-04654. Molecular formula: C8H14N3O6P. Mole weight: 279.19. Purity: 0.99. |  |
| Cidofovir | Cidofovir (GS 0504) is an acyclic monophosphate nucleotide analogue and CMV inhibitor with antiviral activity. Cidofovir inhibits cytomegalovirus (CMV) replication by selectively inhibiting viral DNA polymerase. Cidofovir induces apoptosis and can be used in studies of AIDS cytomegalovirus retinitis, herpes, and cancer [1] [3]. Cidofovir also has anti- orthopoxvirus and anti-variola activities [4]. Uses: Scientific research. Group: Natural products. Alternative Names: GS 0504; HPMPC; (S)-HPMPC. CAS No. 113852-37-2. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17438. | |
| Cidofovir, anhydrous | Cidofovir, anhydrous. Group: Biochemicals. Grades: Highly Purified. CAS No. 113852-37-2. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C8H14N3O6P. US Biological Life Sciences. | Worldwide |
| Cidofovir Dihydrate | 1-[(S)-3-hydroxy-2-(phosphonomethoxy)propyl]cytosine dihydrate. CAS No. 149394-66-1. Product ID: 8-04716. Molecular formula: C8H14N3O6P 2H2O. Mole weight: 315.22. | |
| Cidofovir Diphosphate | Cidofovir Diphosphate - a powerful antiviral agent - is essential in combating cytomegalovirus (CMV) retinitis in AIDS patients. This innovative compound can also effectively treat other herpesvirus infections, including herpes simplex virus (HSV) and varicella-zoster virus (VZV). Its mechanism of action involves the inhibition of viral DNA synthesis and the suppression of viral particle replication, mitigating the continued spread of the virus. Synonyms: (S)-1-(3-Hydroxy-2-phosphonylmethoxyproypl)Cytosine-Diphosphate. Grades: ≥90% by AX-HPLC. Molecular formula: C8H16N3O12P3. Mole weight: 439.10. | |
| Cidofovir Diphosphate Trisodium Salt | Cidofovir Diphosphate Trisodium Salt has antiviral activity, which is used against herpes viruses. Cidofovir Diphosphate is a metabolite in human cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 352525-57-6. Pack Sizes: 500ug, 1mg. Molecular Formula: C8H13N3Na3O12P3, Molecular Weight: 505.09. US Biological Life Sciences. | Worldwide |
| Cidofovir hydrate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Cidofovir Hydrate | An injectable antiviral medication for the treatment of cytomegalovirus (CMV) retinitis in patients with AIDS. It suppresses CMV replication by selective inhibition of viral DNA polymerase and therefore prevention of viral replication and transcription. It is used in the treatment of acyclovir resistant herpes as well as a complementary intralesional therapy against papillomatosis caused by human papillomavirus (HPV). Group: Biochemicals. Alternative Names: [ [ (1S) -2- (4-Amino-2-oxo-1 (2H) -pyrimidinyl) -1- (hydroxymethyl) ethoxy] methyl] phosphonic Acid Hydrate; 1-[ (S) -3-Hydroxy-2- (phosphonomethoxy) propyl]cytosine Hydrate; (S) - [ [2- (4-Amino-2-oxo-1 (2H) -pyrimidinyl) -1- (hydroxymethyl) ethoxy] methyl] phosphonic Acid Hydrate; (S) -1- (3-hydroxy-2-phosphonomethoxypropyl ) cytosine Hydrate; (S)-HPMPC Hydrate; Cidovir Hydrate; GS 0504 Hydrate; Vistide Hydrate. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| C.I. Food Black 2 | C.I. Food Black 2. Uses: Designed for use in research and industrial production. CAS No. 2118-39-0. Purity: 0.95. Product ID: ACM2118390. Alfa Chemistry ISO 9001:2015 Certified. Categories: 2,7-Naphthalenedisulfonic acid. | |
| Ciforadenant | Ciforadenant (CPI-444) is a potent, orally active and selective adenosine A2A receptor ( A2AR ) antagonist, which induces antitumor responses [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CPI-444; V81444. CAS No. 1202402-40-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101978. | |
| Ciglitazone | Selective PPARgamma agonist (EC50=3uM). Hypoglycemic agent. Angiogenesis inhibitor. Anti-inflammatory. Apoptosis inducer. Group: Biochemicals. Grades: Highly Purified. CAS No. 74772-77-3. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C18H23NO3S. US Biological Life Sciences. | Worldwide |
| Ciglitazone | Ciglitazone is a potent and selective PPARγ agonist ( EC 50 =3 μM). Ciglitazone inhibits proliferation and differentiation of th17 cells. Ciglitazone is a hypoglycemic agent orally active in the obese-hyperglycemic animal models. Ciglitazone induces apoptosis accompanied by activation of p38 MAPK and nuclear translocation of apoptosis inducing factor (AIF) in opossum kidney (OK) renal epithelial cells [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ADD-3878; U-63287. CAS No. 74772-77-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W011220. | |
| Ciglitazone | Ciglitazone is a selective agonist at peroxisome proliferator-activated receptor γ (PPARγ) with an EC50 value of 3 μM in vitro. It is at least 33-fold selective over PPARα and &delta. It shows antihyperglycemic activity in genetically obese C57 B1/6 ob/ob mice and is used as an antihyperglycemic agent. Uses: Hypoglycemic agents. Synonyms: ADD 3878; ADD-3878; ADD3878; Ciglitazona; U 63287; U-63287; U63287; ADD 3878; ADD-3878; ADD3878; (+/-) -5-[4- (1-methylcyclohexylmethoxy) benzyl]thiazolidine-2, 4-dione; ADD-3878; 5-[[4-[ (1-Methylcyclohexyl) methoxy]phenyl]methyl]-2, 4-thiazolidinedione. Grades: ≥99% by HPLC. CAS No. 74772-77-3. Molecular formula: C18H23NO3S. Mole weight: 333.44. | |
| Ciglitazone ( ( + / -) -5- [4- (1- methyl cyclohexylmethoxy) benzyl] thiazolidine-2, 4-dione, ADD-3878) | Displays antihyperglycemic activity in genetically obese mice. It is a selective PPARg agonist. Group: Biochemicals. Alternative Names: ( + / -) -5- [4- (1- methyl cyclohexylmethoxy) benzyl] thiazolidine-2, 4-dione; ADD-3878. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Ciglitazone ( (±) -5- [4- (1- methyl cyclohexylmethoxy) benzyl] thiazolidine-2, 4-dione, ADD-3878) | An antidiabetic drug. A thiazolidinedione (TDZ) type of antihyperglycemic agent. It displays antihyperglycemic activity in genetically obese C57 Bl/6 ob/ob mice and is a selective PPARγ agonist (EC50 = 3uM). Group: Biochemicals. Alternative Names: (±) -5- [4- (1- methyl cyclohexylmethoxy) benzyl] thiazolidine-2, 4-dione. Grades: Highly Purified. CAS No. 74772-77-3. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Ciglitazone - CAS 74772-77-3 | A potent thiazolinedione (TDZ) type anti-hyperglycemic agent and a selective PPAR? agonist (EC?? = 3 μM). Group: Fluorescence/luminescence spectroscopy. | |
| Ciglitizone | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CIL-102 | ?95% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| Cilantro (Coriander Leaf) Herb Powder | Cilantro (Coriander Leaf) Herb Powder. |  CA, FL & NJ |
| Cilastatin | Prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. Antibacterial adjunct.Cilastatin is an inhibitor of dipeptidase (dehydropeptidase I), a renal dipeptidase.1 It inhibits human renal dipeptidase (Ki = 0.7uM), porcine dipeptidase (IC50 = 0.11uM), and bacterial metallo- β-lactamase CphA from A. hydrophila (IC50 = 178uM).1,2,3 Cilastatin (200ug/ml) protects primary porcine renal proximal tubular epithelial cells from nephrotoxicity and apoptosis induced by vancomycin.4 In a mouse model of systemic infection, cilastatin in combination with imipenem protects mice from S. aureus, E. coli, and P. aeruginosa infection.5 Cilastatin was designed to inhibit renal metabolism of imipenem and prolong its half-life.2 Formulations containing cilastatin in combination with imipenem have been used to treat susceptible bacterial infections. Group: Biochemicals. Alternative Names: (2Z) -7- [ [ (2R) -2-amino-2-carboxyethyl] thio] -2- [ [ [ (1S) -2, 2-dimethylcyclopropyl] carbonyl] amino] -2-heptenoic Acid; MK-791. Grades: Highly Purified. CAS No. 82009-34-5. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C??H??N?O?S, Molecular Weight: 358.45. US Biological Life Sciences. | Worldwide |
| Cilastatin | Cilastatin (MK0791) is a reversible, competitive renal dehydropeptidase I inhibitor with an IC50 of 0.1 μM. Cilastatin inhibits the bacterial metallob-lactamase enzyme CphA with an IC50 of 178 μM. Cilastatin is an antibacterial adjunct. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Cilastatin. Product Category: Inhibitors. Appearance: White to Light-Yellow Crystalline Powder. CAS No. 82009-34-5. Molecular formula: C16H26N2O5S. Mole weight: 358.45. Purity: 0.9937. Density: 1.275 g/cm³. Product ID: ACM82009345. Alfa Chemistry ISO 9001:2015 Certified. | |
| Cilastatin | Cilastatin can prevent renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. It can be used as antibacterial adjunct. Uses: Antibacterial adjunct. Synonyms: (2Z)-7-[[(2R)-2-amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoic Acid;MK-791; MK 791; MK791. Grades: >95%. CAS No. 82009-34-5. Molecular formula: C16H26N2O5S. Mole weight: 358.45. | |
| Cilastatin | Cilastatin (MK0791) is a reversible, competitive renal dehydropeptidase I inhibitor with an IC 50 of 0.1 μM. Cilastatin inhibits the bacterial metallob-lactamase enzyme CphA with an IC 50 of 178 μM. Cilastatin is an antibacterial adjunct [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK0791. CAS No. 82009-34-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-A0166. | |
| Cilastatin ammonium salt | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Cilastatin Ammonium Salt | Cilastatin Ammonium Salt is the ammonium salt of Cilastatin, which is a dipeptidase inhibitor of renal enzyme dehydropeptidase-I and leukotriene D4 peptidase. It inhibits metabolism of LTD4 to LTE4 and the hydrolysis of β-lactam antibiotics. It reduces toxic accumulation of cyclosporin A in kidney proximal tubule epithelial cells. It can be combined intravenously with imipenem in order to protect it from dehydropeptidase. It suppresses both host and target metabolism of the broad-spectrum antibiotic imipenem, improving its efficacy. It usually confers antibiotic resistance to certain bacteria because itself does not have antibiotic activity. It has nephroprotective effects. Synonyms: (2Z)-7-[[(2R)-2-amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoic Acid Ammonium Salt; MK-791 Ammonium Salt. Grades: > 95%. CAS No. 877674-82-3. Molecular formula: C16H29N3O5S. Mole weight: 375.48. | |
| Cilastatin Enantiomer | Cilastatin Enantiomer. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-7-(((S)-2-amino-2-carboxyethyl)thio)-2-((R)-2,2-dimethylcyclopropanecarboxamido)hept-2-enoic acid. CAS No. 107872-24-2. Molecular formula: C16H26N2O5S. Mole weight: 358.45. Catalog: APB107872242. | |
| Cilastatin Impurity 2 | Cilastatin Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 107873-05-2. Molecular formula: C16H26N2O5S. Mole weight: 358.45. Catalog: APB107873052. | |
| Cilastatin Impurity 4 | Cilastatin Impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1401730-23-1. Molecular formula: C15H24BrNO3. Mole weight: 346.26. Catalog: APB1401730231. | |
| Cilastatin sodium | Cilastatin sodium is the sodium salt of cilastatin, which is a dipeptidase inhibitor of renal enzyme dehydropeptidase-I and leukotriene D4 peptidase. It inhibits metabolism of LTD4 to LTE4 and the hydrolysis of β-lactam antibiotics. It reduces toxic accumulation of cyclosporin A in kidney proximal tubule epithelial cells. It can be combined intravenously with imipenem in order to protect it from dehydropeptidase. It suppresses both host and target metabolism of the broad-spectrum antibiotic imipenem, improving its efficacy. It usually confers antibiotic resistance to certain bacteria because itself does not have antibiotic activity. It has nephroprotective effects. Synonyms: L 642957; MK 791; L642957; MK791; L-642957; MK-791; [R-[R*,S*-(Z)]]-7-[(2-Amino-2-carboxyethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]-2-heptenoic Acid Monosodium Salt; (2Z) ?-7- [ [ (2R) ?-2-Amino-2-carboxyethyl] ?thio] ?-2- [ [ [ (1S) ?-2, ?2-dimethylcyclopropyl] ?carbonyl] ?amino] ?-2-heptenoic Acid Sodium Salt; sodium S-((Z)-6-carboxy-6-((S)-2,2-dimethylcyclopropane-1-carboxamido)hex-5-en-1-yl)-L-cysteinate. Grades: ≥99% by HPLC. CAS No. 81129-83-1. Molecular formula: C16H25N2NaO5S. Mole weight: 380.43. | |
| Cilastatin sodium | Cilastatin sodium (MK0791 sodium) is a reversible, competitive renal dehydropeptidase I inhibitor with an IC50 of 0.1 μM. Cilastatin sodium inhibits the bacterial metallob-lactamase enzyme CphA with an IC50 of 178 μM. Cilastatin sodium is an antibacterial adjunct. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-heptenoicacid,7-((2-amino-2-carboxyethyl)thio)-2-(((2,2-dimethylcyclopropyl;l642957;monosodiumsalt,(r-(r*,s*(z)))-)carbonyl)amino);sodium hydrogen [R-[R*,S*-(Z)]]-7-[(2-amino-2-carboxylatoethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]hept-2-enoate;Cilastatine;Cilastatin sodium;Sodium 7-(2-amino-2-carboxy-ethyl)sulfanyl-2-(2,2-dimethylcyclopropyl)carbonylamino-hept-2-enoate;Sodium hydrogen 7-[(2-amino-2-carboxylatoethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]hept-2-enoate. Product Category: Inhibitors. Appearance: A white colour powder. CAS No. 81129-83-1. Molecular formula: C16H25N2O5S.Na. Mole weight: 380.44. Purity: 95%+. IUPACName: sodium;(Z)-7-[(2R)-2-amino-2-carboxyethyl]sulfanyl-2-[[(1S)-2,2-dimethylcyclopropanecarbonyl]amino]hept-2-enoate. Canonical SMILES: CC1(CC1C(=O)NC(=CCCCCSCC(C(=O)O)N)C(=O)[O-])C.[Na+]. ECNumber: 279-694-4. Product ID: ACM81129831. Alfa Chemistry ISO 9001:2015 Certified. | |
| Cilastatin sodium | Cilastatin sodium. Group: Biochemicals. Grades: Highly Purified. CAS No. 81129-83-1. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C16H25N2NaO5S. US Biological Life Sciences. | Worldwide |
| Cilastatin sodium | Cilastatin sodium (MK0791 sodium) is a reversible, competitive renal dehydropeptidase I inhibitor with an IC 50 of 0.1 μM. Cilastatin sodium inhibits the bacterial metallob-lactamase enzyme CphA with an IC 50 of 178 μM. Cilastatin sodium is an antibacterial adjunct [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK0791 sodium. CAS No. 81129-83-1. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-A0166A. | |
| Cilastatin sodium Ready Made Solution | 50 mg/mL in H2O. Group: Fluorescence/luminescence spectroscopy. | |
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