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| Product | Description | |
|---|---|---|
| Clozapine Impurity 11 | Clozapine Impurity 11. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-((4-chloro-2-(sulfoamino)phenyl)amino)benzoic acid. Molecular Formula: C13H11ClN2O5S. Mole Weight: 342.01. Catalog: APB04322. |  |
| Clozapine Impurity 12 | Clozapine Impurity 12. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5H-dibenzo[b,e][1,4]diazepin-11(10H)-one. CAS No. 5814-41-5. Molecular Formula: C13H10N2O. Mole Weight: 210.08. Catalog: APB5814415. | |
| Clozapine Impurity 6 | Clozapine Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1025951-76-1. Molecular Formula: C20H21ClN4O. Mole Weight: 368.86. Catalog: APB1025951761. | |
| Clozapine Impurity 7 | Clozapine Impurity 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 60091-87-4. Molecular Formula: C13H9ClN2O4. Mole Weight: 292.68. Catalog: APB60091874. | |
| Clozapine Impurity 7 | Clozapine Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(2-aminobenzamido)benzoic acid. CAS No. 612-34-0. Molecular Formula: C14H12N2O3. Mole Weight: 256.08. Catalog: APB612340. | |
| Clozapine Impurity 8 | Clozapine Impurity 8. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(2-((4-chloro-2-nitrophenyl)amino)benzamido)benzoic acid. Molecular Formula: C20H14ClN3O5. Mole Weight: 411.80. Catalog: APB04323. | |
| Clozapine Impurity 8 | Clozapine Impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 67990-66-3. Molecular Formula: C13H11ClN2O2. Mole Weight: 262.69. Catalog: APB67990663. | |
| Clozapine Impurity 9 | Clozapine Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 63687-95-6. Molecular Formula: C17H18N4O. Mole Weight: 294.36. Catalog: APB63687956. | |
| Clozapine Impurity A | 8-Chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]-diazepin-11-one is a useful intermediate for the preparation of pharmaceutical actives and fine chemicals. Synonyms: 8-Chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]-diazepin-11-one. Grades: > 95%. CAS No. 50892-62-1. Molecular formula: C13H9ClN2O. Mole weight: 244.68. |  |
| Clozapine N-Glucuronide | Clozapine N-Glucuronide. Uses: For analytical and research use. Group: Impurity standards. CAS No. 165602-86-8. Molecular Formula: C24H27N4O6. Mole Weight: 502.95. Catalog: APB165602868. | |
| Clozapine N-oxide | Clozapine N-oxide is a major metabolite of Clozapine and a human muscarinic designer receptors (DREADDs) agonist. Clozapine N-oxide activates the DREADD receptor hM3Dq and hM4Di. Clozapine N-oxide can cross the blood-brain barrier [1] [2] [3] [4]. Clozapine is a potent dopamine antagonist and also a potent and selective muscarinic M4 receptor ( EC 50 =11 nM) agonist [5] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 34233-69-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17366. |  |
| Clozapine N-Oxide | Clozapine N-oxide is a major metabolite of clozapine, and acts as an antagonist of 5-HT receptor. Uses: Antipsychotic agents. Synonyms: 3-chloro-6-(4-methyl-4-oxidopiperazin-4-ium-1-yl)-11H-benzo[b][1,4]benzodiazepine. Grades: >98%. CAS No. 34233-69-7. Molecular formula: C18H19ClN4O. Mole weight: 342.827. | |
| Clozapine N-oxide dihydrochloride | Clozapine N-oxide dihydrochloride is a water-soluble salt of Clozapine N-oxide. Clozapine N-oxide is a major metabolite of clozapine and an activator of designer receptors exclusively activated by designer drugs (DREADDs) derived from human muscarinic acetylcholine receptors. It exhibits improved bioavailability (6 - 7-fold higher plasma concentration) compared with CNO, with less conversion to clozapine in animal studies. Synonyms: 8-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine dihydrochloride; CNO. Grades: ≥99% by HPLC. CAS No. 2250025-93-3. Molecular formula: C18H19ClN4O·2HCl. Mole weight: 415.74. | |
| Clozapine N-oxide dihydrochloride | Clozapine N-oxide dihydrochloride is a major metabolite of Clozapine and a human muscarinic designer receptors (DREADDs) agonist. Clozapine N-oxide dihydrochloride activates the DREADD receptor hM3Dq and hM4Di. Clozapine N-oxide dihydrochloride can cross the blood-brain barrier [1] [2] [3] [4]. Clozapine is a potent dopamine antagonist and also a potent and selective muscarinic M4 receptor ( EC 50 =11 nM) agonist [5] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2250025-93-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17366A. | |
| Clozapine (Standard) | Clozapine (Standard) is the analytical standard of Clozapine. This product is intended for research and analytical applications. Clozapine (HF 1854) is an antipsychotic used for the research of schizophrenia. Clozapine has high affinity for a number of neuroreceptors. Clozapine is a potent antagonist of dopamine D2 with a K i of 75 nM. Clozapine inhibits the muscarinic M1 receptor and serotonin 5HT2A receptor with K i s of 9.5 nM and 4 nM, respectively [1] [2] [3]. Clozapine is also a potent and selective agonist at the muscarinic M4 receptor ( EC 50 =11 nM) [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HF 1854 (Standard). CAS No. 5786-21-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14539R. | |
| CLP 257 | CLP 257. Group: Biochemicals. Grades: Purified. CAS No. 1181081-71-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| CLP 257 | CLP 257 has been found to be a KCC2 K+-Cl- cotransporter activator and could alleviates hypersensitivity in rats with peripheral nerve injury. Synonyms: CLP 257; CLP-257; CLP257; (5Z)-5-[(4-Fluoro-2-hydroxyphenyl)methylene]-2-(tetrahydro-1-(2H)-pyridazinyl)-4(5H)-thiazolone. Grades: ≥98% by HPLC. CAS No. 1181081-71-9. Molecular formula: C14H14FN3O2S. Mole weight: 307.34. | |
| Cl-PEG4-acid | Cl-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 158553-98-1. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-W096129. | |
| CLR1501 | CLR1501 is a selective fluorescent compound for cancer cells. Synonyms: 5, 5-Difluoro-10- (4- (18- ( (oxido (2- (trimethylammonio) ethoxy) phosphoryl) oxy) octadecyl) phenyl) -5H-dipyrrolo[1, 2-c: 2', 1'-f][1, 3, 2]diazaborinin-4-ium-5-uide. Grades: 98%. CAS No. 1250963-36-0. Molecular formula: C38H59BF2N3O4P. Mole weight: 701.67. | |
| CLS-011A | CLS-011A is a small molecule used as an antineoplastic and eye disorder therapy. Study indicated its excellent tolerance. Uses: Antineoplastic and eye disorder therapy. Synonyms: CLS 011A. | |
| Cl--transporting ATPase | A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. An animal and plant enzyme involved in the import of chloride anions. Group: Enzymes. Synonyms: Cl--translocating ATPase; Cl--motive ATPase. Enzyme Commission Number: EC 3.6.3.11. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4648; Cl--transporting ATPase; EC 3.6.3.11; Cl--translocating ATPase; Cl--motive ATPase. Cat No: EXWM-4648. |  |
| Cluster Dextrin | Cluster Dextrin. |  CA, FL & NJ |
| CLZ-8 | CLZ-8 (Compound 8) is an orally active Mcl-1-PUMA interface inhibitor, with a K i of 0.3 μM. CLZ-8 exhibits dual activity on reduce PUMA-dependent apoptosis while deactivating Mcl-1-mediated anti-apoptosis in cancer cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 678158-55-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122627. | |
| CM03 | CM03 is a potent DNA G-quadruplexes (G4s) ligand. CM03 can stabilise G4s, downregulating more G4-containing genes as well as increasing incidence of double-strand break events (DSBs) due to torsional strain on DNA and chromatin structure. CM03 has selective potency for pancreatic cancer cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2101208-44-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121862. | |
| CM1 | CM1 is an orally active iron chelator with high selectivity for iron(III). It can penetrate hepatocytes. CM1 is potentially used for patients with thalassaemia related iron overload and exhibits an inhibitory effect on the growth of Plasmodium falciparum (malaria parrasite; IC50 value 35 μM). Uses: The treatment of thalassaemia related iron overload. Synonyms: CM-1; CM 1; 1-(N-acetyl-6-aminohexyl)-3-hydroxy-2-methylpyridin-4-one. Grades: 99%. CAS No. 1643659-63-5. Molecular formula: C14H22N2O3. Mole weight: 266.34. | |
| CM 10 | CM 10 is an inhibitor of aldehyde dehydrogenase 1A (ALDH1A) inhibitor. It can induce a necroptotic phenotype and preferentially deplete CD133+ ovarian cancer stem cells in vitro. Synonyms: 2-(2-Propen-1-yl)-6-[[(1-propyl-1H-benzimidazol-2-yl)amino]methyl]phenol. Grades: ≥98% by HPLC. CAS No. 692269-09-3. Molecular formula: C20H23N3O. Mole weight: 321.42. | |
| CM-24 | CM-24 is a humanized antibody expressed in CHO cells, targeting CEACAM1/CD66a. The predicted molecular weight (MW) of CM-24 is 145 kDa. The isotype control for CM-24 can refer to Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1783801-93-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990569. | |
| CM-3 | CM-3 is a synthetic construct with antibacterial activity. | |
| CM-352 | CM-352 has been found to be a MMP inhibitor that could probably be used as an antihemorrhagic agent with little influence in normal hemostatic function. Synonyms: CM352; CM 352; CM-352; (R) -N-hydroxy-2- ( (4- (4- (methylcarbamoyl) phenoxy) phenyl) sulfonyl) -8-azaspiro[4. 5]decane-2-carboxamide. Grades: 98%. CAS No. 1542205-83-3. Molecular formula: C24H29N3O6S. Mole weight: 487.57. | |
| CM398 | CM398 is a highly selective, orally active sigma-2 receptor ligand ( K i =0.43 nM), with high sigma-1/sigma-2 selectivity rato (1000-fold). CM398 shows notable affinity for dopamine (K i =32.90 nM) and serotonin transporters (K i =244.2 nM). CM398 shows promising anti-inflammatory analgesic effects in the formalin model of inflammatory pain in mice [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1121931-70-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145628. | |
| CMA | CMA is a murine-selective agonist of STING. It triggers type I IFN response in murine macrophages, without effect on human STING signaling. Synonyms: 9-Oxo-10(9H)-acridineacetic acid. Grades: ≥98% by HPLC. CAS No. 38609-97-1. Molecular formula: C15H11NO3. Mole weight: 253.25. | |
| CMC-Na | CMC-Na (Sodium carboxymethyl cellulose) is one of the important modified cellulose, a water-soluble cellulose, which is widely used in many application of food, pharmaceuticals, detergent, paper coating, dispersing agent, and others. CAS No. 9004-32-4. Product ID: PE-0150. Category: Binder Excipients. Product Keywords: Pharmaceutical Excipients; Solid Dosage Form; Binder Excipients; CMC-Na; PE-0150; 9004-32-4; 9004-32-4. Purity: 0.9972. Synonym(s): Sodium carboxymethyl cellulose. Storage: 3 years -20°C powder. |  |
| CMD178 TFA | CMD178 (TFA) is a peptide, which consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/sIL-2Rα signaling. Synonyms: H-Arg-Phe-Lys-Phe-Tyr-OBn.TFA; L-arginyl-L-phenylalanyl-L-lysyl-L-phenylalanyl-L-tyrosine benzyl ester trifluoroacetic acid; RFKFY-OBn.TFA; CMD 178 TFA; CMD-178 TFA. Grades: 98%. CAS No. 2703745-81-5. Molecular formula: C46H59N9O7.C2HF3O2. Mole weight: 964.05. | |
| Cmda | Heterocyclic Organic Compound. CAS No. 122665-73-0. Molecular formula: C17H23ClN2O8S. Mole weight: 450.89. Catalog: ACM122665730. |  |
| CM-Dextran sodium salt | CM-Dextran sodium salt. Group: Natural polymers and biopolymerspolysaccharide. CAS No. 39422-83-8. |  |
| c-Met inhibitor 1 | c-Met inhibitor 1 is an inhibitor of the c-Met receptor signaling pathway useful for the treatment of cancer including gastric, glioblastoma, and pancreatic cancer. Synonyms: c-Met inhibitor 1; c Met inhibitor 1. Grades: >98%. CAS No. 1357072-61-7. Molecular formula: C17H14N8S. Mole weight: 362.41. | |
| c-Met, Phosphotyrosine1003, Negative Control Peptide (Hepatocyte Growth Factor Receptor, Scatter Factor Receptor, HGFRR) | c-Met, Phosphotyrosine1003, Negative Control Peptide (Hepatocyte Growth Factor Receptor, Scatter Factor Receptor, HGFRR). Group: Molecular Biology. Grades: Highly Purified. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
| c-Met, Phosphotyrosine1003, Positive Control Peptide (Hepatocyte Growth Factor Receptor, Scatter Factor Receptor, HGFRR) | c-Met, Phosphotyrosine1003, Positive Control Peptide (Hepatocyte Growth Factor Receptor, Scatter Factor Receptor, HGFRR). Group: Molecular Biology. Grades: Highly Purified. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
| c-Met pYpYpY1230/1234/1235, Negative Control Peptide (Hepatocyte Growth Factor Receptor, Scatter Factor Receptor, HGFR, SFR) | c-Met pYpYpY1230/1234/1235, Negative Control Peptide (Hepatocyte Growth Factor Receptor, Scatter Factor Receptor, HGFR, SFR). Group: Molecular Biology. Grades: Highly Purified. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
| c-Met pYpYpY1230/1234/1235, Positive Control Peptide (Hepatocyte Growth Factor Receptor, Scatter Factor Receptor, HGFR, SFR) | c-Met pYpYpY1230/1234/1235, Positive Control Peptide (Hepatocyte Growth Factor Receptor, Scatter Factor Receptor, HGFR, SFR). Group: Molecular Biology. Grades: Highly Purified. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
| CMG-101 | CMG-101 is a novel selective inhibitor of mTORC1/2. Studies suggest that CMG-101 would overcome the drug resistance of mTORC1 inhibitor through the activation of signal transduction pathways via mTORC2. CMG-101 is promisingly to be a antitumor drug. Uses: Potential antitumor drug. Synonyms: CMG101; CMG 101. | |
| CMHPG | CMHPG. |  |
| CMI-392 | CMI-392 is a dual antagonist of 5-lipoxygenese (IC50= 100 nM) and platelet-activating factor (PAF) receptor (IC50= 10 nM). Uses: Lipoxygenase inhibitors. Synonyms: 3-[[2-[2-(4-chlorophenyl)sulfanylethoxy]-3-methoxy-5-[(2S,5S)-5-(3,4,5-trimethoxyphenyl)oxolan-2-yl]phenyl]methyl]-1-hydroxy-1-methylurea; 2-(3-methoxy-4-(4-chlorophenylthioethoxy)-5-(N-methyl-N-hydroxyureidyl)methylphenyl)-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran; CMI 392; CMI-392. CAS No. 205654-37-1. Molecular formula: C31H37ClN2O8S. Mole weight: 633.15. | |
| CMI-977 | CMI-977, an oxolan compound, has been found to be a 5-Lipoxygenases inhibitor and was once studied as an antiasthmatic agent. Synonyms: CMI-977; CMI 977; CMI977; LPD-977; LPD 977; LPD977; MLN-977; MLN977; MLN 977; 1-[4-[(2S,5S)-5-[(4-fluorophenoxy)methyl]oxolan-2-yl]but-3-ynyl]-1-hydroxyurea. Grades: 98%. CAS No. 175212-04-1. Molecular formula: C16H19FN2O4. Mole weight: 322.34. | |
| CMIT/MIT mixture | Household cleaning products. Group: Biocide and algicide. Alternative Names: Isothiazolinone. CAS No. 55965-84-9. Molecular formula: C4H4ClNOS. Mole weight: 149.56. Catalog: ACM55965849. | |
| CMK | CMK is a RSK2 kinase inhibitor which exhibits similar potency but less chemical stability compared with FMK. Uses: Scientific research. Group: Signaling pathways. CAS No. 821794-90-5. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-52101. | |
| CMK | CMK is a RSK2 kinase inhibitor. Its IC50 value for Cdc5(L158G) is 36 nM. It is used in the preparation of serine/threonine kinase inhibitors. Uses: Cmk is used in the preparation of serine/threonine kinase inhibitors. Synonyms: 1-(4-Amino-7-(3-hydroxypropyl)-5-(p-tolyl)-7h-pyrrolo[2,3-d]pyrimidin-6-yl)-2-chloroethanone. Grades: 95%. CAS No. 821794-90-5. Molecular formula: C18H19ClN4O2. Mole weight: 358.82. | |
| Cm-p1 | Cm-p1 was found in marine snail Cenchritis muricatus. This peptide demonstrated the capacity to prevent the development of yeasts and filamentous fungi. Otherwise, Cm-p1 displayed no toxic effects against mammalian cells. | |
| CMP5 | CMP5 is a potent and selective PRMT5 inhibitor suppressing EBV-driven B-lymphocyte transformation while leaving normal B cells unaffected. Inhibition of PRMT5 effetively blocked recall T cell responses, reduced inflammation in delayed-type hypersensitivity and clinical disease in experimental autoimmune encephalomyelitis mouse models. Synonyms: CMP5; CMP 5; CMP-5; 1-(9-ethylcarbazol-3-yl)-N-(pyridin-2-ylmethyl)methanamine Hydrochloride; AKOS032401780. Grades: 99%. CAS No. 1030021-40-9. Molecular formula: C20H22N3.HCl. Mole weight: 351.87. | |
| CMP-5 | CMP-5 is a potent, specific, and selective PRMT5 inhibitor, while displays no activity against PRMT1, PRMT4, and PRMT7 enzymes. CMP-5 selectively blocks S2Me-H4R3 by inhibiting PRMT5 methyltransferase activity on histone preparations. CMP-5 prevents Epstein-Barr virus (EBV)-driven B-lymphocyte transformation but leaving normal B cells unaffected [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 880813-42-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120137. | |
| CMP8 | CMP8 is a selective ligand for the estrogen receptor, which can bind to the ligand binding domain of the estrogen receptor. The IC50 values of CMP8 for mutant MGERα, MGRERα and wild-type hERα and hERβ are 29 nM, 41 nM, 1100 nM and 2200 nM, respectively. Grades: 98%. CAS No. 851107-28-3. Molecular formula: C33H34ClNO3. Mole weight: 528.1. | |
| CMP-9-fluoresceinyl-NeuAc | CMP-9-fluoresceinyl-NeuAc, is shown to be a suitable donor substrate for sialyltransferase, which belongs to glycosyltransferase family 29. Synonyms: N-Acetyl-9-deoxy-9-[[[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)amino]thioxomethyl]amino]-2-(hydrogen 5'-cytidylate) β-Neuraminic Acid; 5-(Acetylamino)-3,5,9-trideoxy-9-[[[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)amino]thioxomethyl]amino]-D-glycero-β-D-galacto-2-Nonulopyranosonic Acid 2-(Hydrogen 5'-cytidylate); Spiro[isobenzofuran-1(3H),9'-[9H]xanthene] D-glycero-β-D-galacto-2-nonulopyranosonic acid Deriv. CAS No. 118720-35-7. Molecular formula: C41H43N6O20PS. Mole weight: 1002.85. | |
| CMP-CP | CMP-CP is a non-hydrolytic analogue of CDP. It is commonly used as a starting structure in the synthesis of α/β hydrolysis-resistant tri- and polyphosphates. Synonyms: Cytidine- 5'- O- (α, β- methylene)diphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 101536-15-6. Molecular formula: C10H17N3O10P2 (free acid). Mole weight: 401.2 (free acid). | |
| CMPD-1 | CMPD-1. Group: Biochemicals. Grades: Purified. CAS No. 41179-33-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CMPD-1 | CMPD-1, also called MK2a Inhibitor, inhibits tubulin polymerisation. It inhibit p38α-mediated MK2a phosphorylation (apparent Ki = 330 nM). Synonyms: CMPD1; CMPD-1; CMPD 1; IN1225; IN-1225; IN 1225; 4-[4-(2-fluorophenyl)phenyl]-N-(4-hydroxyphenyl)butanamide; MK2a Inhibitor; MAPKAPK2a Inhibitor; CMPD1; CHEMBL235658; 41179-33-3; IN1225; 4-(2' -Fluorobiphenyl-4-yl)-N-(4-hydroxyphenyl)-butyramide; Mitogen-activated protein kinase-activated protein kinase 2a Inhibitor; MK2a Inhibitor_x000D_; SCHEMBL169905. CAS No. 41179-33-3. Molecular formula: C22H20FNO2. Mole weight: 349.4. | |
| CMPD101 | CMPD101 is a selective GRK2/3 inhibitor with IC50 value is 54 nM for GRK3 and 32 nM for GRK2. It shows selectivity for GRK2/3 over GRK1/5. It can also reduce DAMGO-induced desensitization and internalization of μ-opioid receptors. Synonyms: CMPD101; CMPD 101; CMPD-101; Takeda101; Takeda-101; Takeda 101. 3-[[[4-Methyl-5- (4-pyridinyl) -4H-1, 2, 4-triazol-3-yl]methyl]amino]-N-[[2- (trifluoromethyl) phenyl]methyl]benzamide. Grades: 98%. CAS No. 865608-11-3. Molecular formula: C24H21F3N6O. Mole weight: 466.46. | |
| CMPD101 | CMPD101 is a novel, potent and selective G-protein coupled receptor kinase 2 and 3 (GRK2/GRK3) inhibitor (IC50 values are 35 and 32 nM at GRK2 and GRK3 respectively). CMPD101 exhibits selectivity for GRK2/3 over GRK1/5 and reduces DAMGO-induced desensitization and internalization of μ-opioid receptors. CMPD101 has been shown to potentiate phosphatidylinositol 4,5-bisphosphate (PIP2) depletion and slow agonist-induced desensitization of protease-activated receptor 2 (PAR2). Group: Inhibitors. Alternative Names: CMPD101; CMPD 101; CMPD-101; Takeda101; Takeda-101; Takeda 101. CAS No. 865608-11-3. Molecular formula: C24H21F3N6O. Mole weight: 466.47. Appearance: Solid powder. Purity: >98%. IUPACName: 3-[[[4-Methyl-5- (4-pyridinyl) -4H-1, 2, 4-triazol-3-yl]methyl]amino]-N-[[2- (trifluoromethyl) phenyl]methyl]benzamide. Canonical SMILES: O=C (NCC1=CC=CC=C1C (F) (F)F)C2=CC=CC (NCC3=NN=C (C4=CC=NC=C4)N3C)=C2. Catalog: ACM865608113. | |
| CMPDA | CMPDA is a positive allosteric modulator of AMPA receptors. Binds at the modulator binding pocket located at the interdimer interface and the clamshell hinges. Synonyms: CMPDA; 380607-77-2; N,N'-(1,4-Phenylenedi-2,1-ethanediyl)bis-2-propanesulfonamide; A36XX25K37; N-[2-[4-[2- (propan-2-ylsulfonylamino) ethyl]phenyl]ethyl]propane-2-sulfonamide; N,N'-(Benzene-1,4-Diyldiethane-2,1-Diyl)dipropane-2-Sulfonamide; 2-Propanesulfonamide, N,N'-(1,4-phenylenedi-2,1-ethanediyl)bis-; UNII-A36XX25K37; SCHEMBL6565144; BCP23929; AKOS024458123; CS-3632; HY-12508; MS-26117; E99011; Q27465085; N,N'-(2,2'-(1,4-phenylene)bis(ethane-2,1-diyl))dipropane-2-sulfonamide; RNN. Grades: >98%. CAS No. 380607-77-2. Molecular formula: C16H28N2O4S2. Mole weight: 376.53. | |
| CMPDA (N,N'-1,4-Phenylenedi-2,1-ethanediyl bis-2-propanesulfonamide) | CMPDA (N,N'-1,4-Phenylenedi-2,1-ethanediyl bis-2-propanesulfonamide). Group: Biochemicals. Grades: Highly Purified. CAS No. 380607-77-2. Pack Sizes: 10mg. Molecular Formula: C16H28N2O4S2, Biological Activity: Positive allosteric modulator of GluR2 receptors (EC50 values are 45.4 and 63.4 nM at GluR2i and GluR2o respectively, in a calcium influx screening assay). Binds at the modulator binding pocket located at the interdimer interface and the clamshell hinges. US Biological Life Sciences. | Worldwide |
| CMPF | CMPF can be found in trace constituent of urine and blood. CMPF is a biomarker of type 2 diabetes. CMPF can act on the β cell and induces impaired mitochondrial function. CMPF decreases glucose-induced ATP accumulation, and induces oxidative stress. CMPF reverses hepatic lipid accumulation and improves insulin sensitivity in obese mice [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 86879-39-2. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-129297. | |
| CMPI [2-Chloro-1-methylpyridinium iodide] | CMPI [2-Chloro-1-methylpyridinium iodide]. Group: Biochemicals. Grades: Highly Purified. CAS No. 14338-32-0. Pack Sizes: 50g, 100g, 250g, 500g. US Biological Life Sciences. | Worldwide |
| CMP - lyophilized | CMP - lyophilized is an extensively employed biomolecule in the field of biomedical sciences due to its pivotal involvement in the intricate processes of DNA research and development and repair. Through serving as a fundamental constituent for nucleic acids, CMP assuming a critical role in facilitating cellular functions. Synonyms: Cytidine-5'-monophosphate, Disodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C9H14N3O8P (free acid). Mole weight: 323.20 (free acid). | |
| CMP-N-acetylneuraminate monooxygenase | This enzyme contains both a Rieske-type [2Fe-2S] cluster and a second iron site. The ferricytochrome b5 produced is reduced by NADH and cytochrome-b5 reductase (EC 1.6.2.2). The enzyme can be activated by Fe2+ or Fe3+. Group: Enzymes. Synonyms: CMP-N-acetylneuraminic acid hydroxylase; CMP-Neu5Ac hydroxylase; cytidine monophosphoacetylneuraminate monooxygenase; N-acetylneuraminic monooxygenase; cytidine-5'-monophosphate-N-acetylneuraminic acid hydroxylase. Enzyme Commission Number: EC 1.14.18.2. CAS No. 116036-67-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0964; CMP-N-acetylneuraminate monooxygenase; EC 1.14.18.2; 116036-67-0; CMP-N-acetylneuraminic acid hydroxylase; CMP-Neu5Ac hydroxylase; cytidine monophosphoacetylneuraminate monooxygenase; N-acetylneuraminic monooxygenase; cytidine-5'-monophosphate-N-acetylneuraminic acid hydroxylase. Cat No: EXWM-0964. | |
| CMP-N-acetylneuraminic acid 9-sp-biotin | | |
| CMP-N-acetylneuraminic acid sodium salt | CMP-N-acetylneuraminic acid sodium salt, a fundamental compound employed in the field of biomedicine, exhibits immense utility in the management of diverse ailments associated with compromised sialic acid metabolism, including sialuria and sialic acid storage diseases. Synonyms: CMP-NANA; Cytidine 5-monophospho-b-D-N-acetylneuraminic acid sodium salt; CMP-Sialic Acid; CMP-Neu5Ac. CAS No. 3063-71-6. Molecular formula: C20H30N4O16P Na. Mole weight: 636.43. | |
| CMP-N-acylneuraminate phosphodiesterase | This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. Group: Enzymes. Synonyms: CMP-sialate hydrolase; CMP-sialic acid hydrolase; CMP-N-acylneuraminic acid hydrolase; cytidine monophosphosialic hydrolase; cytidine monophosphosialate hydrolase; cytidine monophosphate-N-acetylneuraminic acid hydrolase; CMP-N-acetylneuraminate hydrolase. Enzyme Commission Number: EC 3.1.4.40. CAS No. 55326-41-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3724; CMP-N-acylneuraminate phosphodiesterase; EC 3.1.4.40; 55326-41-5; CMP-sialate hydrolase; CMP-sialic acid hydrolase; CMP-N-acylneuraminic acid hydrolase; cytidine monophosphosialic hydrolase; cytidine monophosphosialate hydrolase; cytidine monophosphate-N-acetylneuraminic acid hydrolase; CMP-N-acetylneuraminate hydrolase. Cat No: EXWM-3724. | |
| CMP-Neu5,9Ac2 | CMP-Neu5,9Ac2 serves as a direct substrate of the NeuA O-acetyl esterase in vitro. Synonyms: β-Neuraminic acid, N-acetyl-, 9-acetate 2-(hydrogen 5'-cytidylate), ammonium salt (1:2). CAS No. 1045785-97-4. Molecular formula: C22H33N4O17P.2NH3. Mole weight: 690.55. | |
| CMP-Neu5Ac sodium salt | CMP-Neu5Ac sodium salt, a vital compound in the biomedical sector, is intricately involved in numerous biological processes, aiding in the synthesis of sialylated compounds. Notably, its indispensable role as a substrate for sialyltransferases facilitates the treatment of ailment manifestations characterized by aberrant sialylation. Afflicting individuals are plagued by a range of conditions, including cancer, neurological disorders, and autoimmune diseases, wherein CMP-Neu5Ac sodium salt assumes significance. Synonyms: CMP-NANA; Cytidine 5'-monophospho-b-D-N-acetylneuraminic acid sodium salt; CMP-N-acetylneuraminic acid sodium salt; CMP-Sialic Acid. Grades: 85%. CAS No. 1007117-62-5. Molecular formula: C20H30N4O16P·Na. Mole weight: 636.43. | |
| CMP-N-glycolylneuraminic acid | CMP-N-glycolylneuraminic acid is a fundamental compound extensively used in the biomedical field, serving as an indispensable precursor in the research and development of diverse sialic acid derivatives, which wield significant influence over a plethora of intricate biological mechanisms. Synonyms: N-(2-hydroxyacetyl)-b-neuraminic acid 2-(hydrogen 5-cytidylate); CMP-NeuGc. CAS No. 98300-80-2. Molecular formula: C20H31N4O17P. Mole weight: 630.45. | |
| CMP-N,N'-diacetyllegionaminic acid synthase | Isolated from the bacteria Legionella pneumophila and Campylobacter jejuni. Involved in biosynthesis of legionaminic acid, a sialic acid-like derivative that is incorporated into virulence-associated cell surface glycoconjugates which may include lipopolysaccharide (LPS), capsular polysaccharide, pili and flagella. Group: Enzymes. Synonyms: CMP-N,N'-diacetyllegionaminic acid synthetase; neuA (gene name); legF (gene name). Enzyme Commission Number: EC 2.7.7.82. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3295; CMP-N,N'-diacetyllegionaminic acid synthase; EC 2.7.7.82; CMP-N,N'-diacetyllegionaminic acid synthetase; neuA (gene name); legF (gene name). Cat No: EXWM-3295. | |
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