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A component of the alternative pathway of complement activation. This reaction is analogous to the activation of complement component C2 by complement subcomponent C1s. In peptidase family S1 (trypsin family). Group: Enzymes. Synonyms: C3 proactivator convertase; properdin factor D esterase; factor D; factor D (complement). Enzyme Commission Number: EC 3.4.21.46. CAS No. 37213-56-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4139; complement factor D; EC 3.4.21.46; 37213-56-2; C3 proactivator convertase; properdin factor D esterase; factor D; factor D (complement). Cat No: EXWM-4139.
Activated from proenzyme C1r in plasma during activation of the complement system by the "classical" route. In peptidase family S1 (trypsin family). Group: Enzymes. Synonyms: activated complement C1r; C1r esterase; activated complement C1r. Enzyme Commission Number: EC 3.4.21.41. CAS No. 80295-69-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4135; complement subcomponent C1r; EC 3.4.21.41; 80295-69-8; activated complement C1r; C1r esterase; activated complement C1r. Cat No: EXWM-4135.
complement subcomponent C1s
Activated from proenzyme C1s in plasma by complement subcomponent C1r. In peptidase family S1 (trypsin family). Group: Enzymes. Synonyms: C1 esterase; activated complement C1s; complement C1r. Enzyme Commission Number: EC 3.4.21.42. CAS No. 80295-70-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4136; complement subcomponent C1s; EC 3.4.21.42; 80295-70-1; C1 esterase; activated complement C1s; complement C1r. Cat No: EXWM-4136.
Complete Freund's adjuvant (CFA)
Complete Freund's adjuvant (CFA) is an immunoadjuvant emulsified with antigen by its discoverer Jules T. Freund to enhance an animal's immune response to an antigen. Complete Freund's adjuvant (CFA) is also an inducer of the Th1 immune response and a ligand of TLRs. Complete Freund's adjuvant (CFA) contains heat-killed inactive tuberculosis bacilli and consists of a paraffin oil-in-water emulsion. Complete Freund's adjuvant (CFA) stimulates a strong and durable immune response and can be used to induce persistent inflammatory pain models in mice, experimental autoimmune myocarditis (EAM) models, and more. Incomplete Freund's adjuvant (IFA) (HY-153808A) is another type of Freund's Adjuvant that stimulates a weaker immune response[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9007-81-2. Pack Sizes: 10 mL; 10 mL * 2; 10 mL * 5. Product ID: HY-153808.
Completely Denatured Alcohol CDA 12A 275 TOTE
275 gallons of product. Group: Denatured Ethanol. Grades: Made with 200 Proof USP grade ethanol. Completely denatured alcohol formula CDA 12A-1 denatured with n-heptane. Categories: CDA Completely Denatured Alcohol.
Completely Denatured Alcohol CDA 12A 330 TOTE
330 gallons of product. Group: Denatured Ethanol. Grades: Made with 200 Proof USP grade ethanol. Completely denatured alcohol formula CDA 12A-1 denatured with n-heptane. Categories: CDA Completely Denatured Alcohol.
Completely Denatured Alcohol CDA 12A BULK
Tanker volume. Group: Denatured Ethanol. Grades: Made with 200 Proof USP grade ethanol. Completely denatured alcohol formula CDA 12A-1 denatured with n-heptane. Categories: CDA Completely Denatured Alcohol.
Completely Denatured Alcohol CDA 12A DRUM
55 gallons of product. Group: Denatured Ethanol. Grades: Made with 200 Proof USP grade ethanol. Completely denatured alcohol formula CDA 12A-1 denatured with n-heptane. Categories: CDA Completely Denatured Alcohol.
Completely Denatured Alcohol CDA 12A GALLON
1 gallon of product. Made with 200 Proof USP grade ethanol. Completely denatured alcohol formula CDA 12A-1 denatured with n-heptane. Group: Denatured Ethanol. Categories: CDA Completely Denatured Alcohol.
Completely Denatured Alcohol CDA 12A GALLON CASE
4 gallons of product (4 bottles). Made with 200 Proof USP grade ethanol. Completely denatured alcohol formula CDA 12A-1 denatured with n-heptane. Group: Denatured Ethanol. Categories: CDA Completely Denatured Alcohol.
Completely Denatured Alcohol CDA 12A PALE
5 gallons of product. Made with 200 Proof USP grade ethanol. Completely denatured alcohol formula CDA 12A-1 denatured with n-heptane. Group: Denatured Ethanol. Categories: CDA Completely Denatured Alcohol.
Complex Mixture of PAHs from Coal Tar
Complex Mixture of PAHs from Coal Tar. Uses: For analytical and research use. Group: Polycyclic aromatic hydrocarbons (pahs). Catalog: APS006929. Shipping: Room Temperature.
Adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 less potent than AdipoRon. Activates 5'-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells. Improves diabetes, glucose and lipid metabolism and insulin sensitivity in cultured cells and in mice by AdipoR-dependent mechanisms. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Compound 34
Cell permeable, highly potent inhibitor of gamma-secretase (IC50 = 0.06nM). Group: Biochemicals. Alternative Names: (2S,3R)-3-(3,4-Difluorophenyl)-2-(4-fluorophenyl)-4-hydroxy-N-((3S)-2-oxo-5-phenyl-2,3-1H-benzodiazepin-3-yl)butyramide. Grades: Highly Purified. CAS No. 564462-36-8. Pack Sizes: 200ug, 1mg. Molecular Formula: C31H24F3N3O3. US Biological Life Sciences.
Worldwide
Compound 401
Compound 401 is a synthetic inhibitor of DNA-PK (IC50 = 0.28 μM) that also targets mTOR but not PI3K in vitro. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 168425-64-7. Molecular formula: C16H15N3O2. Purity: >99 %. Product ID: ACM168425647. Alfa Chemistry ISO 9001:2015 Certified.
Compound 401
Compound 401. Group: Biochemicals. Grades: Purified. CAS No. 168425-64-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Compound 401
Compound 401, a pyrimido-isoquinolinone compound, is a selective and cell-permeable inhibitor that has an reversible function on DNA-dependent protein kinase (DNA-PK). It is also a mammalian target of rapamycin (mTOR) with little affinity for 43 other com. Synonyms: 2-morpholin-4-ylpyrimido[2,1-a]isoquinolin-4-oneCompound 401; Compound-401; Compound401;168425-64-72-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-oneCHEMBL1792422-Morpholin-4-yl-pyrimido[2,1-a]isoquinolin-4-oneSCHEMBL10092321CTK4D2994S-7713; S 7713; S77132-(morpholin-4-yl)pyrimido[2,1-a]iso. Grades: >99 %. CAS No. 168425-64-7. Molecular formula: C16H15N3O2. Mole weight: 281.31.
Cell-permeable. A reversible and selective inhibitor of DNA-dependent protein kinase (DNA-PK) (IC?? = 0.28uM) that also targets mTOR (IC50 = 5. 3uM), but not PI 3-K in vitro. Induces apoptosis in vitro. Group: Biochemicals. Grades: Highly Purified. CAS No. 168425-64-7. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Compound 401 - CAS 168425-64-7
A cell-permeable pyrimido-isoquinolinone compound that acts as a potent, reversible, and ATP-competitive inhibitor of DNA-PK (IC?? = 280 nM) with ~19-fold selectivity over mTOR (IC?? = 5.3 μM). Group: Fluorescence/luminescence spectroscopy.
Compound 43 TAO Kinase Inhibitor
Compound 43 TAO kinase inhibitor is an ATP-competitive and selective inhibitor of TAOK1 and TAOK2 (IC50s = 11 and 15 nM, respectively). It is selective for TAOK1 and TAOK2 over 62 kinases in a panel, but does inhibit TAOK3 by 87% and seven additional kinases by 21-52%. Synonyms: N-[2-oxo-2-[(1,2,3,4-tetrahydro-1-naphthalenyl)amino]ethyl]-[1,1'-biphenyl]-4-carboxamide. Grades: ≥98%. CAS No. 850467-66-2. Molecular formula: C25H24N2O2. Mole weight: 384.47.
Compound 48/80
Compound 48/80 (Poly-p-methoxyphenethylmethylamine) is widely used in animal and tissue models as a "selective" mast cell activator. Compound 48/80 acts at the mast cell membrane to stimulate trimeric G-proteins and induces degranulation via phospholipase C and D pathways [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Poly-p-methoxyphenethylmethylamine. CAS No. 94724-12-6. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-115768.
Compound 48/80 hydrochloride
Compound 48/80 is a condensation product of N-methyl-p-methoxyphenethylamine with formaldehyde that causes histamine degranulation from mast cells. Compound 48/80 also inhibits human platelet aggregation through suppression of calmodulin (CaM) (IC50 = 0.41 μg/ml for CaM-dependent Ca2+-transporter ATPase activity) and phospholipase C. Synonyms: 4-methoxy-3,5-bis[[2-methoxy-5-[2-(methylamino)ethyl]phenyl]methyl]-N-methyl-benzeneethanamine trihydrochloride. Grades: ≥95%. CAS No. 848035-21-2. Molecular formula: C32H45N3O3·3HCl. Mole weight: 629.1.
Compound 56
Compound 56 is a highly potent inhibitor of the epidermal growth factor receptor (EGFR; IC50 = 0.006 nM). It has been used to inhibit EGFR activity in pancreatic cancer cell lines and it can induce the differentiation of rat mesenchymal stem cells. Synonyms: N-(3-bromophenyl)-6,7-diethoxy-4-quinazolinamine. Grades: ≥95%. CAS No. 171745-13-4. Molecular formula: C18H18BrN3O2. Mole weight: 388.3.
Compound 56 - CAS 171745-13-4
A cell-permeable, reversible, ATP-competitive, highly potent and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (IC?? = 6 pM). Group: Fluorescence/luminescence spectroscopy.
Compound E is a γ-secretase inhibitor. Compound E blocks β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage with IC 50 s of 0.24, 0.37, 0.32 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: γ-Secretase-IN-1. CAS No. 209986-17-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14176.
Compound E
Compound E is a cell-permeable inhibitor of γ-secretase (GSI), which is a multifunctional transmembrane protein complex enzymatically catalyzing the cleavage of single-pass transmembrane proteins. Compound E can inhibit Notch processing (IC50 = 2.2 nM in SupT1 cells) and β-ammyloid production in cell culture (IC50 = 0.3 nM). Synonyms: γ-Secretase Inhibitor; Gamma-Secretase Inhibitor XXI; (S,S)- 2-[2-(3,5-Difluorophenyl)-acetylamino]-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-propionamide; (2S)-2-{[(3,5-Difluorophenyl)acetyl]amino}-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]propanamide; N2-[(3,5-difluorophenyl)acetyl]-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-L-alaninamide. Grades: 99%. CAS No. 209986-17-4. Molecular formula: C27H24F2N4O3. Mole weight: 490.5.
Compound E
Cell permeable, potent, selective, non-transition state and non-competitive gamma-secretase inhibitor. Notch processing inhibitor. Only weakly affects presenilinase activity. Group: Biochemicals. Alternative Names: (2S)-2-(amino)-N-propanamide. Grades: Highly Purified. CAS No. 209986-17-4. Pack Sizes: 250ug, 1mg, 5mg. Molecular Formula: C27H24F2N4O3. US Biological Life Sciences.
Compound W. Group: Biochemicals. Grades: Purified. CAS No. 173550-33-9. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
Compound W
Compound W, also called 3,5-bis(4-Nitrophenoxy)benzoic acid, a 3,3'-diiodothyronine sulfate cross-reactive substance, is an inhibitor of γ-secretase which causes a decrease in the released levels of Aβ42 and notch-1 Aβ-like peptide 25 (Nβ25). Synonyms: 3,5-bis(4-Nitrophenoxy)benzoic acid; 173550-33-9; gamma-Secretase Modulator, CW; ACMC-1CUIP; SCHEMBL264541; CHEMBL1553155; CTK8B1007; JOSXKPZXMVHRKU-UHFFFAOYSA-; DTXSID10587892; JOSXKPZXMVHRKU-UHFFFAOYSA-N; HMS3269J17; ZINC2576957; ANW-22664; MFCD02093450; AKOS015833412; 3,5-bis (4-nitrophenoxy) benzoic acid; NCGC00167814-01; AJ-42568; AK-63150; EN002659; OR182673; KB-234083; TR-007681; B2120; Compound W|CW|3,5-Bis(4-nitrophenoxy)benzoic acid; BRD-K98143539-001-01-4; I14-62910. Grades: >98.0%(T)(HPLC). CAS No. 173550-33-9. Molecular formula: C19H12N2O8. Mole weight: 396.31.
Compound W (CW, 3,5-Bis(4-nitrophenoxy)benzoic acid)
Compound W is a y-secretase inhibitor that has been shown to lower the levels of secreted Ab42 and Nb25. Group: Biochemicals. Grades: Highly Purified. CAS No. 173550-33-9. Pack Sizes: 50mg, 250mg. US Biological Life Sciences.
Worldwide
Compressible sugar
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Compstatin
Compstatin, a 13-residue cyclic peptide, is a potent inhibitor of the complement system C3 with species specificity. Compstatin binds to baboon C3 and is resistant to proteolytic cleavage in baboon blood (similar to humans). Compstatin inhibits only the activation of primates complement system. Compstatin exhibits IC 50 values of 63 μM and 12 μM for classical and alterative complement pathway, respectively [1] [2] [3] [4]. Uses: Scientific research. Group: Peptides. CAS No. 206645-99-0. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P1036.
Compstatin
Compstatinis, a 13-residue cyclic peptide, is a potent inhibitor of the complement system (IC50= 12 μM) and binds to complement component C3. Synonyms: H-Ile-Cys(1)-Val-Val-Gln-Asp-Trp-Gly-His-His-Arg-Cys(1)-Thr-NH2; L-isoleucyl-L-cysteinyl-L-valyl-L-valyl-L-glutaminyl-L-alpha-aspartyl-L-tryptophyl-glycyl-L-histidyl-L-histidyl-L-arginyl-L-cysteinyl-L-threoninamide (2->12)-disulfide; 2-[(4R, 7S, 10S, 13S, 19S, 22S, 25S, 28S, 31S, 34R)-4-[[(2S, 3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]carbamoyl]-34-[[(2S, 3S)-2-amino-3-methylpentanoyl]amino]-25-(3-amino-3-oxopropyl)-7-[3-(diaminomethylideneamino)propyl]-10, 13-bis(1H-imidazol-5-ylmethyl)-19-(1H-indol-3-ylmethyl)-6, 9, 12, 15, 18, 21, 24, 27, 30, 33-decaoxo-28, 31-di(propan-2-yl)-1, 2-dithia-5, 8, 11, 14, 17, 20, 23, 26, 29, 32-decazacyclopentatriacont-22-yl]acetic acid. Grades: 98%. CAS No. 206645-99-0. Molecular formula: C66H99N23O17S2. Mole weight: 1550.77.
Compstatin
Compstatin. Group: Biochemicals. Grades: Highly Purified. CAS No. 206645-99-0. Pack Sizes: 1mg. Molecular Formula: C66H99N23O17S2, Molecular Weight: 1550.77. US Biological Life Sciences.
Worldwide
Compstatin control peptide
Compstatin control peptide. Group: Biochemicals. Grades: Purified. CAS No. 301544-78-5. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Compstatin control peptide
Compstatin control peptide is a kind of control peptide for compstatin. It is a complement inhibitor. Grades: >98%. CAS No. 301544-78-5. Molecular formula: C66H101N23O17. Mole weight: 1488.67.
Comu
Comu. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylamino-morpholino-carbenium hexafluorophosphate;4-{{[(1-Cyano-2-ethoxy-2-oxoethylidene)amino]oxayl] (dimethylamino)methylene]-hexafluorophosphate;1-[1-(Cyano-2-ethoxy-2-oxoethylideneaMinooxy)-diMethylaMino-Morpholino]-uroniuM hexafluorophosphate;(1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylaminomorpholinocarbenium Hexafluorophosphate (This product is only available in Japan.);COMU(R) 97%;elagolix intermediate 13;COMU 4-{{[(1-Cyano-2-ethoxy-2-oxoethylidene)-amino]-oxayl}-(dimethylamino)-methylene}-hexafluorophosphate morpholinium. Product Category: Heterocyclic Organic Compound. CAS No. 1075198-30-9. Molecular formula: C12H19N4O4.PF6. Mole weight: 0. Product ID: ACM1075198309. Alfa Chemistry ISO 9001:2015 Certified. Categories: Communism.
COMU
COMU is used as an efficient coupling agent in phosphonamidation reactions; used as coupling reagent in the synthesis of solid phase peptide. Synonyms: (1-Cyano-2-ethoxy-2-oxoethylidenaminooxy) dimethylaminomorpholinocarbenium Hexafluorophosphate; (1-Cyano-2-ethoxy-2-oxoethylideneaminooxy)-dimethylamino-morpholino-carbenium hexafluorophosphate; 4-{{[(1-Cyano-2-ethoxy-2-oxoethylidene)amino]oxayl] (dimethylamino)methylene]-hexafluorophosphate; COMU(R); Elagolix intermediate 13. Grades: > 98 % (HPLC). CAS No. 1075198-30-9. Molecular formula: C12H19F6N4O4P. Mole weight: 428.27.
COMU®
Fast coupling efficiency, very low or non-existent tendencies for racemization. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: (1-Cyano-2-ethoxy-2-Oxoethylidenaminooxy) Dimethylamino-morpholino-carbenium hexafluorophosphate. CAS No. 1075198-30-9. registered patent of Luxembourg Bio Technologies.
Luxembourg Bio Technologies
Conagenin
It is produced by the strain of Sreptomyces roseosporus M1696-AF3. It is a low molecular immune modulator. Synonyms: (S)-2-((2R,3S,4R)-2,4-dihydroxy-3-methylpentanamido)-3-hydroxy-2-methylpropanoic acid; N-(3,5-Dideoxy-3-methyl-D-xylonoyl)-2-methyl-L-serine; Conagenine. CAS No. 134381-30-9. Molecular formula: C10H19NO6. Mole weight: 249.26.
Conalbumin
Conalbumin (Ovotransferrin), also known as ovotransferrin, is a monomeric glycoprotein consisting of 686 amino acids, encoded by the avian transferrin gene in the oviduct, and a prominent component of chicken egg white. Exhibiting a unique glycosylation pattern that differentiates it from serum transferrin, Conalbumin is a potent iron binder that plays a crucial role in iron transport to developing embryos. Additionally, it possesses a range of biological activities, including antimicrobial, antifungal, antiviral, anticancer, antioxidative, antihypertensive, and immunoregulatory properties, making it valuable in numerous applications such as infant formula ingredients, food additives, and agents for enhancing animal health. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Ovotransferrin. CAS No. 1391-06-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P2232.