A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
The COX-2 Inhibitor I, also referenced under CAS 416901-58-1, controls the biological activity of COX-2. This small molecule/inhibitor is primarily used for Cell Signaling applications. Uses: For analytical and research use. Group: Fluorescence/luminescence spectroscopy. CAS No. 416901-58-1. Pack Sizes: 5MG. Mole weight: 377.84. Catalog: AP416901581. Assay: ?97% (HPLC).
COX-2 Inhibitor I - CAS 416901-58-1
The COX-2 Inhibitor I, also referenced under CAS 416901-58-1, controls the biological activity of COX-2. This small molecule/inhibitor is primarily used for Cell Signaling applications. Group: Fluorescence/luminescence spectroscopy.
COX-2 Inhibitor II
A selective inhibitor of COX-2. Synonyms: SC-791; IN1371; 181696-33-3; 4-[(5-Difluoromethyl-3-phenyl)-4-isoxazolyl]benzenesulfonamide; SCHEMBL214781. CAS No. 181696-33-3. Molecular formula: C16H12F2N2O3S. Mole weight: 350.34.
COX-2 Inhibitor II - CAS 181696-33-3
The COX-2 Inhibitor II, also referenced under CAS 181696-33-3, controls the biological activity of COX-2. This small molecule/inhibitor is primarily used for Cell Signaling applications. Group: Fluorescence/luminescence spectroscopy.
COX-2 Inhibitor V, FK3311
COX-2 Inhibitor V, FK3311 is a selective Cox-2 inhibitor and NSAID. Group: Biochemicals. Grades: Highly Purified. CAS No. 116686-15-8. Pack Sizes: 5mg, 10mg. Molecular Formula: C15H13F2NO4S, Molecular Weight: 341.33. US Biological Life Sciences.
Worldwide
COX-2 Inhibitor V, FK3311 - CAS 116686-15-8
The COX-2 Inhibitor V, FK3311, also referenced under CAS 116686-15-8, controls the biological activity of COX-2. This small molecule/inhibitor is primarily used for Cell Signaling applications. Group: Fluorescence/luminescence spectroscopy.
COX 2 Upstream Primer, 724bp amplimer (Cyclooxygenase 2, PGHS 2, Prostaglandin Endoperoxide Synthase 2, PHS 2). Group: Molecular Biology. Pack Sizes: 50uM. US Biological Life Sciences.
Worldwide
COX/5-LO-IN-1
A dual inhibitor of cylooxygenase and 5-lipoxygenase. Synonyms: Urea, N-[3-[5-[(4-fluorophenyl)methyl]-2-thienyl]-1-methyl-2-propyn-1-yl]-N-hydroxy-; 1-[4-[5-[(4-fluorophenyl)methyl]thiophen-2-yl]but-3-yn-2-yl]-1-hydroxyurea. CAS No. 154355-75-6. Molecular formula: C16H15FN2O2S. Mole weight: 318.37.
CP-060 is a novel type of Ca(2+) antagonist possessing both Ca(2+) overload inhibition, with antioxidant and cardioprotective activities. Synonyms: CP-060; CP060; CP 060; 3-[3-[2-(1,3-benzodioxol-5-yloxy)ethyl-methylamino]propyl]-2-(3,5-ditert-butyl-4-hydroxyphenyl)-1,3-thiazolidin-4-one. CAS No. 180090-15-7. Molecular formula: C30H42N2O5S. Mole weight: 542.73.
CP-10
CP-10 is a PROTAC connected by ligands for Cereblon and CDK , with highly selective, specific, and remarkable CDK6 degradation ( DC 50 =2.1 nM). It inhibits proliferation of several haematopoietic cancer cells with impressive potency including multiple myeloma, and can still degrades mutated and overexpressed CDK6 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2366268-80-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-125835.
CP-100263 is an NK-1 neurokinin receptor antagonist as testosterone replacement therapy. Group: Biochemicals. Alternative Names: (2R,3R)-N-[(2-methoxyphenyl)methyl]-2-phenyl-3-piperidinamine Dihydrochloride Hydrate; (2R-cis)-N-[(2-methoxyphenyl)methyl]-2-phenyl-3-piperidinamine Dihydrochloride Hydrate; (-)-CP 99994 Dihydrochloride Hydrate; CP 100263 Dihydrochloride Hydrate. Grades: Highly Purified. CAS No. 872726-33-5. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
CP 100356
CP 100356 is a high affinity P-glycoprotein inhibitor.Ki value is 58 nM for mouse Pgp1a and 94nMfor Pgp1b isoforms. It can Inhibit calcein-AM uptake in MDR1-transfected MDCKII cells with IC50 value of 0.5 μM and prazosin transport in BCRP-transfected MDCKII cells with IC50 value of 1.5 μM. Preclinical development for Cancer in USA was discontinued. Uses: Cancer. Synonyms: CP 100356; CP100356; CP-100356; 4-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-N-(2-(3,4-dimethoxyphenyl)ethyl)-6,7-dimethoxy-2-Quinazolinamine; 142715-48-8(hydrochloride). Grade: >98 %. CAS No. 142716-85-6. Molecular formula: C31H36N4O6. Mole weight: 560.64.
CP 100356 hydrochloride
The hydrochloride salt form of CP-100356, which has been found to be an inhibitor of MDR1 (P-Gp) and show inactive in inhibiting multidrug resistance-associated protein 2 (MPR2). Synonyms: CP 100356 hydrochloride; CP100356 hydrochloride; CP-100356 hydrochloride; 4-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-N-2[2-(3,4-dimethoxyphenyl)ethyl]-6,7-dimethoxy-2-quinazolinamine hydrochloride. Grade: ≥98% by HPLC. CAS No. 142715-48-8. Molecular formula: C31H36N4O6.HCl. Mole weight: 597.10.
CP-100356 hydrochloride
CP-100356 hydrochloride is an orally active dual MDR1 (P-gp)/BCRP inhibitor, with an IC50s of 0.5 and 1.5 μM for inhibiting MDR1-mediated Calcein-AM transport and BCRP-mediated Prazosin transport, respectively. CP-100356 hydrochloride is also a weak inhibitor of OATP1B1 (IC50=?66 μM). CP-100356 hydrochloride is devoid of inhibition against MRP2 and major human P450 enzymes (IC50>15 μM)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 142715-48-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108347.
CP-100356 Hydrochloride
CP-100356 is a specific inhibitor of MDR1 (P-Gp), the protypical ABC transporter. CP-100356 also inhibits prazosin transport in human breast cancer resistance protein (BCRP)-transfected MDCKII cells, suggesting that it acts as a dual inhibitor. CP-100356 does not inhibit multidrug resistance-associated protein 2 (MPR2 IC50 >15 mM). Group: Biochemicals. Alternative Names: 4-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-6,7-dimethoxy-2-quinazolinamine Monohydrochloride. Grades: Highly Purified. CAS No. 142715-48-8. Pack Sizes: 10mg. US Biological Life Sciences.
A highly selective antagonist for NR2B subunit containing nMDA receptors (IC50 = 0.039uM for NR2B and >100uM for NR2A, NR2C, and NR2D). Widely used as neuroprotective, analgesic, antidepressant, and anti-Parkinsonian agent in research. Group: Biochemicals. Grades: Highly Purified. CAS No. 134234-12-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
CP-10447
An inhibitor apolipoprotein B (apoB) and triglyceride secretion in human hepatoma cells (HepG2) by inhibiting MTP activity and stimulating the early ER degradation of apoB. It is useful tool for further study of the mechanisms of apoB secretion and triglyceride-rich lipoprotein assembly. Group: Biochemicals. Alternative Names: 3-(4-Bromo-2-methylphenyl)-2-methyl-4(3H)-quinazolinone; CP 10447; 3-(4-Bromo-o-tolyl)-2-methyl-4(3H)-quinazolinone. Grades: Highly Purified. CAS No. 843-93-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
CP-105696
CP-105696, a chromen derivative, has been found to be a leukotriene B4 receptor antagonist that was once studied against sorts of nflammatory disease. Uses: Leukotriene antagonists. Synonyms: CP-105696; UNII-Z7354TW4BM; CP-105,696; CHEMBL51770; CP 105696; Z7354TW4BM; 1-[(3S,4R)-4-hydroxy-3-[(4-phenylphenyl)methyl]-3,4-dihydro-2H-chromen-7-yl]cyclopentane-1-carboxylic acid. Grade: 98%. CAS No. 158081-99-3. Molecular formula: C28H28O4. Mole weight: 428.53.
CP-105696
CP-105696 is a potent and selective Leukotriene B4 Receptor antagonist, with an IC50 of 8.42 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Pfizer 105696. CAS No. 158081-99-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19193.
CP-114271, a thiazole derivative, has been found to be a β3 adrenergic receptor agonist that was once studied in obesity therapy. Synonyms: CP-114271; CP 114271; CP114271; UL-TG 307; UL-TG-307; UNII-CY8W406YBX.; UL-TG 307; UL-TG-307; CY8W406YBX; Acetic acid, (4-((2R)-2-(((2S)-2-hydroxy-2-(2-(trifluoromethyl)-4-thiazolyl)ethyl)amino)propyl)phenoxy)-. Grade: 98%. CAS No. 162326-86-5. Molecular formula: C17H19F3N2O4S. Mole weight: 404.40.
CP 115953
CP 115953 is a Type II DNA topoisomerase inhibitor originated by Pfizer. CP 115953 inhibits topoisomerase II activity via an interaction with the enzyme and not by DNA unwinding. It can stimulate cytokine production by lymphocytes. Research for treatment of cancer was discontinued. Uses: Cancer. Synonyms: CP 115953; CP115953; CP-115953; 1-Cyclopropyl-6,8-difluoro-1,4-dihydro-7-(4-hydroxyphenyl)-4-oxo-3-quinolinecarboxylic acid. Grade: 98%. CAS No. 136440-70-5. Molecular formula: C19H13F2NO4. Mole weight: 357.31.
CP 117227
CP 117227, a dibenzocyclohepten derivative, has been found to be a Type II DNA topoisomerase inhibitor that was once developed in studies of anticancer. Synonyms: CP 117227; CP-117227; CP117227; 1-Piperazineethanol, 4-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-yl)-alpha-((5-quinolinyloxy)methyl)-, (S)-. Grade: 98%. CAS No. 154531-78-9. Molecular formula: C31H33N3O2. Mole weight: 479.61.
CP-120509
It is produced by the strain of Actinomadura roseorufa 263606. CP-120509 has anti-gram-positive bacteria, spirochete and spirochete activity, and also has a good anti-coccidiosis effect caused by Eimeria acervulina, E. tenella. Molecular formula: C45H76O17. Mole weight: 889.07.
CP-122721
CP-122721, a phenylpiperidin derivative, has been found to be a NK1 receptor antagonist that could probably be effective as antidepressant and antiemetic agent. The result of Phase II clinical trial for depression of it has not been reported yet since 2003. Synonyms: CP122721; CP 122721; 3-(2-methoxy-5-trifluoromethoxybenzyl)amino-2-piperidine. Grade: 98%. CAS No. 145742-28-5. Molecular formula: C20H23F3N2O2. Mole weight: 380.40.
CP 135807
CP 135807, an indole derivative, has been found to be a selective 5-HT1D receptor agonist. Synonyms: CP135807; CP-135807; 3-(N-Methylpyrrolidin-2-ylmethyl)-5-(3-nitropyrid-2-ylamino)-1H-indole; (R)-3-((1-Methyl-2-pyrrolidinyl)methyl)-N-(3-nitro-2-pyridinyl)-1H-indol-5-amine. Grade: ≥98% by HPLC. CAS No. 151272-90-1. Molecular formula: C19H21N5O2. Mole weight: 351.40.
CP-135807
A selective 5-HT1D receptor agonist. Group: Biochemicals. Alternative Names: 3-[[(2R)-1-Methyl-2-pyrrolidinyl]methyl]-N-(3-nitro-2-pyridinyl)-1H-indol-5-amine;(R)-3-[(1-Methyl-2-pyrrolidinyl)methyl]-N-(3-nitro-2-pyridinyl)-1H-indol-5-amine; CP 135807. Grades: Highly Purified. CAS No. 151272-90-1. Pack Sizes: 10mg. US Biological Life Sciences.
CP 141938 is a potent and selective neurokinin-1 (NK1) receptor antagonist with very different brain tendencies and potency in centrally mediated activity models. Synonyms: Methanesulfonamide, N-[4-methoxy-3-[[[(2R,3R)-2-phenyl-3-piperidinyl]amino]methyl]phenyl]-N-methyl-, rel-; Methanesulfonamide, N-[4-methoxy-3-[[(2-phenyl-3-piperidinyl)amino]methyl]phenyl]-N-methyl-, cis-; rel-N-[4-Methoxy-3-[[[(2R,3R)-2-phenyl-3-piperidinyl]amino]methyl]phenyl]-N-methylmethanesulfonamide; CP141938; CP-141938. Grade: ≥95%. CAS No. 182822-62-4. Molecular formula: C21H29N3O3S. Mole weight: 403.54.
CP-141938
CP-141938. Group: Biochemicals. Alternative Names: rel-N- [4-Methoxy-3- [ [ [ (2R, 3R) -2-phenyl-3-piperidinyl] amino] methyl] phenyl] -N-methyl-methanesulfonamide. Grades: Highly Purified. CAS No. 182822-62-4. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C21H29N3O3S. US Biological Life Sciences.
Worldwide
CP 154526
The hydrochloride salt form of CP-154526, which has been found to be a non-peptide CRF1 receptor antagonist and could exhibit anxiolytic-like activity at some extent. Synonyms: CP 154526; CP154526; CP-154526; N-Butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine hydrochloride. Grade: ≥99% by HPLC. CAS No. 257639-98-8. Molecular formula: C23H32N4.HCl. Mole weight: 400.99.
CP 154526 hydrochloride
CP 154526 hydrochloride is a potent, brain-penetrant and selective corticotropin-releasing factor receptor 1 (CRF1) antagonist with a K i of 2.7 nM. CP 154526 hydrochloride shows selective for CRF1 over CRF2 (K i=>10 μM). CP 154526 hydrochloride has anxiolytic activities [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 257639-98-8. Pack Sizes: 5 mg. Product ID: HY-12129.
A selective, non-peptide antagonist of corticotropin releasing factor receptors (CRF1). It blocks CRF-induced adenylate cyclase activation and attenuates activation of the HPA axis by CRF. It displayed anxiolytic-like activity in the rat elevated plus-maze test; brain penetrant. Group: Biochemicals. Alternative Names: N-Butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine Hydrochloride. Grades: Highly Purified. CAS No. 257639-98-8. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
CP-195494
CP-195494, a benzothiazol derivative, was once studied as a leukotriene receptor antagonist. Synonyms: UNII-1D055URF6U; CHEMBL300701; CP195494; CP 195494; CP-195494; (+)-CP-195494; 1D055URF6U; BDBM50070919. Grade: 98%. CAS No. 158103-57-2. Molecular formula: C26H22F4N2O5S2. Mole weight: 582.59.
CP-195543
CP-195543 is a potent and selective leukotriene B4 antagonist developed as an oral treatment for for inflammatory diseases. Synonyms: 2-[(3S,4R)-3-benzyl-4-hydroxy-3,4-dihydro-2H-chromen-7-yl]-4-(trifluoromethyl)benzoic acid; 2-(3-benzyl-4-hydroxy-chroman-7-yl)-4-trifluoromethyl-benzoic acid; CP 195543; CP-195543; CP195543. Grade: >98%. CAS No. 204981-48-6. Molecular formula: C24H19F3O4. Mole weight: 428.4.
CP-199330
CP-199330, a chromen derivative, has been found to be a Leukotriene D4 receptor antagonist that was once studied against asthma by Pfizer. Synonyms: CP-199330; CP 199330; CP199330; UNII-V4WYK6T8QA; CHEMBL96206; V4WYK6T8QA; SCHEMBL8890632; BDBM50081532; N-[3-[[(3R,4R)-6-[(7-chloroquinolin-2-yl)methoxy]-4-hydroxy-3,4-dihydro-2H-chromen-3-yl]methyl]-4-methoxyphenyl]-1,1,1-trifluoromethanesulfonamide. Grade: 98%. CAS No. 158102-92-2. Molecular formula: C28H24ClF3N2O6S. Mole weight: 609.01.
CP-199330 Sodium
The sodium salt form of CP-199330 which is a chromen derivative and has been found to be a Leukotriene D4 receptor antagonist that was once studied against asthma by Pfizer. Synonyms: CP-199330 sodium; CP 199330 sodium; CP199330 sodium; CP-199330 monosodium salt; Methanesulfonamide, N-(3-((6-((7-chloro-2-quinolinyl)methoxy)-3,4-dihydro-4-hydroxy-2H-1-benzopyran-3-yl)methyl)-4-methoxyphenyl)-1,1,1-trifluoro-, monosodium salt, (3R-cis)-; UNII-74573Q728X component FZCWCSNK. Grade: 98%. CAS No. 158102-98-8. Molecular formula: C28H23ClF3N2NaO6S. Mole weight: 630.99.
CP2
CP2 is a cyclic peptide and it is an inhibitor of the JmjC histone demethylases KDM4 with IC50 values of 42 nM and 29 nM for KDM4A and KDM4C, respectively. Grade: ≥97%. Molecular formula: C92H120N24O26S. Mole weight: 2010.15.
CP21R7
CP21R7 is a potent and selective GSK3β inhibitor. It acts as an activator of stem cells prior to the induction of differentiation of stem cells to endothelial and smooth muscle cells. Uses: Cp21r7 is a selective gsk-3β inhibitor which could probably influence luciferase activity at some extent. Synonyms: 3-(3-aminophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione. Grade: >98%. CAS No. 125314-13-8. Molecular formula: C19H15N3O2. Mole weight: 317.34.
CP21R7
CP21R7 is potent GSK-3? inhibitor, with an IC50 of 1.8 nM; CP21R7 also shows inhibitory activitiy against PKC?, with an IC50 of 1900 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP21. CAS No. 125314-13-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100207.
CP-220629
CP-220629, a Pyrazolopyridin derivative, has been found to be a Type 4 cyclic nucleotide phosphodiesterase inhibitor that was once studied as an anti-inflammatory as well as antiasthmatic agent. Synonyms: UNII-BAV9N49AFE; CP-220629; CP 220629; CP220629; BAV9N49AFE; SCHEMBL84865; CHEMBL75819; 1-cyclopentyl-3-ethyl-6-(2-methylphenyl)-4,5-dihydropyrazolo[3,4-c]pyridin-7-one. Grade: 98%. CAS No. 162141-96-0. Molecular formula: C20H25N3O. Mole weight: 323.44.
CP22185
CP22185 is a catecholamine-uptake inhibitor. Synonyms: CP-22185; CP 22185; Sertraline hydrochloride specified impurity B; (1RS,4RS)-N-Methyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-1-amine; N-Methyl-4alpha-phenyltetralin-1alpha-amine. Grade: 98%. CAS No. 52758-03-9. Molecular formula: C17H19N. Mole weight: 237.34.
CP-225917
CP-225917 inhibits Ras farnesyl transferase from the mouse brain and Squalene synthase. Molecular formula: C31H38O10. Mole weight: 570.63.
CP 226269
CP 226269 is a selective dopamine D4 agonist. Synonyms: CP-226269; CP 226269; CP226269; 5-fluoro-2-[(4-pyridin-2-ylpiperazin-1-yl)methyl]-1H-indole. Grade: 99%. CAS No. 220941-93-5. Molecular formula: C18H19FN4. Mole weight: 310.37.
CP 24,879 is an inhibitor of arachidonic acid biosynthesis by inhibition of Δ5/Δ6 desaturase. Synonyms: p-(Isopentyloxy)-aniline; 4-(3-methylbutoxy)-benzenamine monohydrochloride. Grade: ≥98%. CAS No. 10141-51-2. Molecular formula: C11H17NO·HCl. Mole weight: 215.8.
CP-24879 (hydrochloride) is a potent, selective and combined delta5D/delta6D inhibitor. CP-24879 (hydrochloride) can significantly reduce intracellular lipid accumulation and inflammatory injury in hepatocytes. CP-24879 (hydrochloride) exhibits superior antisteatotic and anti-inflammatory actions in fat-1 and ?-3-treated hepatocytes, and can be used for non-alcoholic steatohepatitis research[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 10141-51-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115319.
CP26
CP26 is a small molecule inhibitor of protein dislocation from the ER lumen to the cytosol. CP26 targets the Hrd1 complex, inhibits ERAD, and induces ER stress [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 500285-30-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-49116.
CP-263114
CP-263114 inhibits Ras farnesyl transferase from the mouse brain and Squalene synthase. CAS No. 186700-09-4. Molecular formula: C31H36O9. Mole weight: 552.61.
CP-283097
CP-283097 is NR2B N-Methyl-D-Aspartate receptor antagonist originated by Pfizer. Preclinical trials for the treatment of Migraine and Neurodegenerative disorders were discontinued. Uses: Migraine; neurodegenerative disorders. Synonyms: CP-283097; CP283097; CP 283097; UNII-WHL1Z3GN15; ; (3R,4S)-Rel-3,4-dihydro-3-(4-hydroxy-4-(phenylmethyl)-1-piperidinyl)-2H-1-benzopyran-4,7-diol. Grade: 98%. CAS No. 138047-56-0. Molecular formula: C21H25NO4. Mole weight: 355.43.
CP-28888
CP-28888, an interferon inducer, is more effective in mice, but less active in humans and lacks anti-rhinovirus effects. Synonyms: CP 28888-27; N,N-Dihexadecyl-1,3-benzenedi(methanamine); 1,3-Benzenedimethanamine, N1,N3-dihexadecyl-; N,N'-[1,3-Phenylenebis(methylene)]di(hexadecan-1-amine); N,N'-[1,3-Phenylenebis(methylene)]di(1-hexadecanamine). Grade: ≥95%. CAS No. 69938-75-6. Molecular formula: C40H76N2. Mole weight: 585.04.
CP-289
CP-289 is an effective C5a receptor antagonist with an IC50 of 1 μM. Grade: >98.0%. CAS No. 1349637-14-4. Molecular formula: C30H35ClN2O2. Mole weight: 491.07.
Cp2C / CppC
Cp2C is an omnipresent chemical compound extensively employed in the realm of biomedical industry, recognized for its profound efficacy in restraining the proliferation of cancerous cells, primarily manifested in breast and lung malignancies. Synonyms: P1, P2- Di- (cytidine- 5')- diphosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 29789-88-6. Molecular formula: C18H26N6O15P2 (free acid). Mole weight: 628.4 (free acid).
CP2 (Nic)
CP2 (Nic) is an efficacious and discriminating allosteric modulator of the α7 nicotinic acetylcholine receptor (nAChR), and exhibits potential utility as a treatment for cognitive deficits linked with Alzheimer's disease. Synonyms: Nicotinamide cytosine dinucleotide, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C20H27N5O15P2 (free acid). Mole weight: 639.40 (free acid).
Cp2-SO4
Cp2-SO4, a phenylalanine derivative, reverses interleukin 4 induced 1 (IL4I1)-dependent inhibition of T-cell proliferation with Ki of 21.2 μM. Molecular formula: C14H23NO6S. Mole weight: 333.40.
CP 31398
CP 31398 is a p53 stabilizer and could probably restrain the growth of small human tumor xenografts in vivo. CP 31398 is a prototype small molecule that stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53. Synonyms: 1,3-Propanediamine, N3-[2-[2-(4-methoxyphenyl)ethenyl]-4-quinazolinyl]-N1,N1-dimethyl-; 1,3-Propanediamine, N'-[2-[2-(4-methoxyphenyl)ethenyl]-4-quinazolinyl]-N,N-dimethyl-; N3-[2-[2-(4-Methoxyphenyl)ethenyl]-4-quinazolinyl]-N1,N1-dimethyl-1,3-propanediamine; CP31398; CP-31398. Grade: ≥95%. CAS No. 259199-65-0. Molecular formula: C22H26N4O. Mole weight: 362.47.
CP 31398 dihydrochloride
CP 31398 is a p53 stabilizer and could probably restrain the growth of small human tumor xenografts in vivo. CP 31398 is a prototype small molecule that stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53. Synonyms: CP31398 dihydrochloride; CP-31398 dihydrochloride; N'-[2-[2-(4-Methoxyphenyl)ethenyl]-4-quinazolinyl]-N,N-dimethyl-1,3-propanediamine dihydrochloride; 1,3-Propanediamine, N3-[2-[2-(4-methoxyphenyl)ethenyl]-4-quinazolinyl]-N1,N1-dimethyl-, hydrochloride (1:2); PZ 0115; N1-(2-(4-methoxystyryl)quinazolin-4-yl)-N3,N3-dimethylpropane-1,3-diamine dihydrochloride. Grade: ≥99% by HPLC. CAS No. 1217195-61-3. Molecular formula: C22H26N4O.2HCl. Mole weight: 435.39.
CP-31398 dihydrochloride
CP-31398 dihydrochloride stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53 [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1217195-61-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18343A.
CP-31398 Dihydrochloride
A styrylquinazoline derivative that acts as a p53 stabilizing agent. It not only restores p53 functions in mutant p53-expressing cells but can also significantly increase the protein level and promote the activity of wild-type p53 in multiple human cancer cell lines, leading to cell cycle arrest or apoptosis. CP-31398 enhances the protein levels of wild-type p53 by blockade of ubiquitination and degradation of p53 without interrupting the physical association between p53 and MDM2 in vivo. Group: Biochemicals. Alternative Names: N'-[2-[2-(4-Methoxyphenyl)ethenyl]-4-quinazolinyl]-N,N-dimethyl-1,3-propanediamine Dihydrochloride. Grades: Highly Purified. CAS No. 259199-65-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
CP 31398 dihydrochloride hydrate
CP 31398 is a p53 stabilizer and could probably restrain the growth of small human tumor xenografts in vivo. CP 31398 is a prototype small molecule that stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53. Synonyms: 1,3-Propanediamine, N3-[2-[2-(4-methoxyphenyl)ethenyl]-4-quinazolinyl]-N1,N1-dimethyl-, hydrochloride, hydrate (1:2:1); CP31398 dihydrochloride hydrate; CP-31398 dihydrochloride hydrate; N'-[2-[2-(4-Methoxyphenyl)ethenyl]-4-quinazolinyl]-N,N-dimethyl-1,3-propanediamine dihydrochloride hydrate; N1-(2-(4-methoxystyryl)quinazolin-4-yl)-N3,N3-dimethylpropane-1,3-diamine dihydrochloride hydrate. Grade: ≥95%. CAS No. 1853109-76-8. Molecular formula: C22H26N4O.2HCl.H2O. Mole weight: 453.41.