A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
CP-31398 Dihydrochloride Hydrate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-[2-[2-(4-Methoxyphenyl)ethenyl]-4-quinazolinyl]-N,N-dimethyl-1,3-propanediamine dihydrochloride hydrate. Appearance: Yellow solid. CAS No. 1217195-61-3. Molecular formula: C22H26N4O. Mole weight: 362.46. Purity: 0.97. Product ID: ACM1217195613. Alfa Chemistry ISO 9001:2015 Certified.
CP-31398 Dihydrochloride Hydrate
CP-31398 Dihydrochloride Hydrate. Group: Biochemicals. Alternative Names: N3-[2-[2-(4-Methoxyphenyl)ethenyl]-4-quinazolinyl]-N1,N1-dimethyl-1,3-propanediamine Hydrochloride Hydrate. Grades: Highly Purified. CAS No. 1217195-61-3. Pack Sizes: 10mg. Molecular Formula: C22H28Cl2N4O; xH2O, Molecular Weight: 435.39. US Biological Life Sciences.
Worldwide
CP-316311
CP-316311, a pyridine derivative, has been found to be a CRF 1 receptor antagonist and was once studied as an antidepressant agent by Pfizer. IC50: 6.8 nM. Synonyms: CP-316311; CP 316311; CP316311; CP-316,311; CP 316,311; CP316,311; Pyridine, 4-(1-ethylpropoxy)-3,6-dimethyl-2-(2,4,6-trimethylphenoxy)-. Grade: 98%. CAS No. 175139-41-0. Molecular formula: C21H29NO2. Mole weight: 327.47.
CP 316819
CP 316819. Group: Biochemicals. Grades: Purified. CAS No. 186392-43-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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CP 316819
CP 316819 has been found to be a glycogen phosphorylase inhibitor and could probably be used in the treatment for glycemic control in type 2 diabetes. Synonyms: CP 316819; CP316819; CP-316819; 5-Chloro-N-[(1S,2R)-2-hydroxy-3-(methoxymethylamino)-3-oxo-1-(phenylmethyl)propyl]-1H-indole-2-carboxamide. Grade: ≥98% by HPLC. CAS No. 186392-43-8. Molecular formula: C21H22ClN3O4. Mole weight: 415.87.
CP-316819
CP 316819 is a potent glycogen phosphorylase (GPase) inhibitor with antihyperglycemic effect (IC50 values are 17 and 34 nM against human skeletal muscle glycogen phosphorylase (huSMGPa) and liver glycogen phosphorylase (huLGPa) respectively).CP 316819 causes glycogen accumulation under normoglycemic conditions but permits glycogen utilization when glucose concentrations are low.CP-316819 prevents neuronal cell death and maintains brain electrical currents[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GPi 819. CAS No. 186392-43-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-108615.
CP-316819
A novel glycogen phosphorylase inhibitor; potential treatment for glycemic control in type 2 diabetes. Group: Biochemicals. Alternative Names: 5-Chloro-N-[(1S,2R)-2-hydroxy-3-(methoxymethylamino)-3-oxo-1-(phenylmethyl)propyl]-1H-indole-2-carboxamide; GPi 819; CP 316 819. Grades: Highly Purified. CAS No. 186392-43-8. Pack Sizes: 10mg. US Biological Life Sciences.
CP-320626, a carboxamide derivative, is a potent glycogen phosphorylase inhibitor and a possible target for type 2 diabetes therapy. CP-320626 is also a potent inhibitor of human muscle GPa. Synonyms: 5-chloro-N-[(2S)-3-(4-fluorophenyl)-1-(4-hydroxypiperidin-1-yl)-1-oxopropan-2-yl]-1H-indole-2-carboxamide; CP-320626; CP320626; CP 320626. Grade: >98%. CAS No. 186430-23-9. Molecular formula: C23H23ClFN3O3. Mole weight: 443.90.
CP-331684
CP-331684 is a β3-adrenergic receptor agonist used as antidiabetic drug. Synonyms: CP-331684; CP331684; CP 331684; UNII-9EY0MGZ7F8. 2-[4-[2-[[(2R)-2-(6-aminopyridin-3-yl)-2-hydroxyethyl]amino]ethoxy]phenyl]acetic acid. Grade: >98%. CAS No. 207922-70-1. Molecular formula: C17H21N3O4. Mole weight: 331.37.
CP-335963. Group: Biochemicals. Alternative Names: 4-Chloro-6, 7-bis (2-methoxyethoxy) quinazoline; 4-Chloro-6, 7-di (2-methoxyethoxy) quinazoline; 6,7-Bis(2-methoxyethoxy)-4-chloroquinazoline; PF-508367. Grades: Highly Purified. CAS No. 183322-18-1. Pack Sizes: 10mg. Molecular Formula: C14H17ClN2O4, Molecular Weight: 312.75. US Biological Life Sciences.
Worldwide
CP 339818
CP 339818 is a non-peptide KV1.3 channel antagonist that is more effective at blocking HCN1 than HCN4. Synonyms: 1-Pentanamine, N-[1-(phenylmethyl)-4(1H)-quinolinylidene]-; N-[1-(Phenylmethyl)-4(1H)-quinolinylidene]-1-pentanamine; (1-Benzyl-1H-quinolin-4-ylidene)-pentyl-amine; 1-Benzyl-N-pentylquinolin-4(1H)-imine; N-(1-Benzylquinolin-4(1H)-ylidene)pentan-1-amine. Grade: ≥95%. CAS No. 185855-91-8. Molecular formula: C21H24N2. Mole weight: 304.43.
CP 339818 hydrochloride is the hydrochloride salt form of CP 339818, a non-peptide KV1.3 channel antagonist that is more effective at blocking HCN1 than HCN4. Synonyms: 1-Pentanamine, N-[1-(phenylmethyl)-4(1H)-quinolinylidene]-, hydrochloride (1:1); 1-Pentanamine, N-[1-(phenylmethyl)-4(1H)-quinolinylidene]-, monohydrochloride; Cp 339818 monohydrochloride; N-[1-(Phenylmethyl)-4(1H)-quinolinylidene]-1-pentanamine hydrochloride; (1-Benzyl-1H-quinolin-4-ylidene)-pentyl-amine hydrochloride; 1-Benzyl-N-pentylquinolin-4(1H)-imine hydrochloride; N-(1-Benzylquinolin-4(1H)-ylidene)pentan-1-amine hydrochloride. Grade: ≥99% by HPLC. CAS No. 478341-55-8. Molecular formula: C21H24N2.HCl. Mole weight: 340.89.
CP 339818 hydrochloride
CP 339818 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 478341-55-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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CP 339818 hydrochloride
CP 339818 hydrochloride is a nonpeptide and selective Kv1.3 ( IC 50 value of ~200 nM) and Kv1.4 channels blocker. CP 339818 hydrochloride is a significantly less potent blocker of Kv1.1, Kv1.2, Kv1.5, Kv1.6, Kv3.1-4, and Kv4.2. CP 339818 hydrochloride potently blocks the C-type inactivated conformation of Kv1.3 and suppresses T cell activation [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 478341-55-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-108574.
CP 346086
CP 346086 is a potent microsomal triglyceride transfer protein (MTP, MTTP) inhibitor. It reduces LDL cholesterol and triglycerides, and can be used for the treatment of obesity. Uses: The treatment of obesity. Synonyms: CP 346086; CP346086; CP-346086; N-[1,2,3,4-Tetrahydro-2-(1H-1,2,4-triazol-5-ylmethyl)-6-isoquinolinyl]-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamide. Grade: 99%. CAS No. 186390-48-7. Molecular formula: C26H22F3N5O. Mole weight: 477.48.
CP-346086
CP-346086 is a potent and orally active microsomal triglyceride transfer protein (MTP) inhibitor, with an IC50 of 2.0 nM for human and rodent MTP. CP-346086 can lower plasma cholesterol and triglycerides in vivo[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 186390-48-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113955.
CP-346086 is microsomal triglyceride transfer protein (MTP, MTTP) inhibitor for treatment of obesity. Group: Biochemicals. Alternative Names: N-[1,2,3,4-Tetrahydro-2-(1H-1,2,4-triazol-5-ylmethyl)-6-isoquinolinyl]-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamide Dihydrate. Grades: Highly Purified. CAS No. 186390-48-7. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
CP-35587
CP-35587 is resistant to gram-positive cocci, but it has no effect on penicillin-resistant Staphylococcus aureus and is active against gram-negative bacteria. Synonyms: Benzeneacetamide, alpha-amino-N-(3,3-dimethyl-7-oxo-2-(1H-tetrazol-5-yl)-4-thia-1-azabicyclo(3.2.0)hept-6-yl)-4-hydroxy-, (2S-(2alpha,5alpha,6beta))-. CAS No. 57089-17-5. Molecular formula: C16H19N7O3S. Mole weight: 389.43.
CP 376395
CP 376395 is a potent and selective CRF1 receptor antagonist. It attenuates CRF-induced activation of the HPA axis in vivo. Synonyms: CP-376395; CP376395. Grade: >99 %. CAS No. 175140-00-8. Molecular formula: C21H30N2O. Mole weight: 326.5.
CP-376395 HCl
CP-376395 HCl is a potent and selective CRF1 receptor antagonist with Ki values of 12 and >10000 nM for CRF1 and CRF2 receptors respectively. It attenuates CRF-induced activation of the HPA axis in vivo. Synonyms: CP376395 HCl; CP 376395 HCl; 2-(Mesityloxy)-3,6-dimethyl-N-(pentan-3-yl)pyridin-4-amine hydrochloride; 3,6-Dimethyl-N-pentan-3-yl-2-(2,4,6-trimethylphenoxy)pyridin-4-amine hydrochloride. Grade: >98 %. CAS No. 1013933-37-3. Molecular formula: C21H31ClN2O. Mole weight: 362.94.
CP 376395 hydrochloride
CP 376395 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1013933-37-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
CP-394531 is an effective Glucocorticoid receptor agonist and probably has steroid-like anti-inflammatory properties with anti-GR and anti-obesity activity in animal models. Uses: Glucocorticoid receptor antagonists. Synonyms: CP-394531; CP 394531; CP394531; UNII-227D9ED2SI. (2R,4aS,10aR)-4a-benzyl-2-(chloroethynyl)-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-2,7-diol. Grade: ≥95%. CAS No. 305822-63-3. Molecular formula: C23H23ClO2. Mole weight: 366.14.
CP-409092
CP-409092 is a GABA(A) partial agonist developed for the treatment of General Anxiety Disorder (GAD) and presents an interesting phenomenon of human pharmacokinetic predictions. In vitro, CP-409092 was abroadly metabolized in rat and human systems predominantly to acid metabolite formed by oxidative deamination of the N-methyl group of CP-409092 mediated by MAO-A (as deduced from inhibition experiments). Synonyms: N-[4-(methylaminomethyl)phenyl]-4-oxo-1,5,6,7-tetrahydroindole-3-carboxamide; 4-oxo-4,5,6,7-tetrahydro-1H-indole-3-carboxylic acid (4-methylaminomethylphenyl)amide; CP 409,092; CP 409092; CP-409,092; CP-409092; CP409,092; CP409092. Grade: >98%. CAS No. 194098-25-4. Molecular formula: C17H19N3O2. Mole weight: 297.35.
CP-409092 hydrochloride
CP-409092 hydrochloride is a GABAA receptor partial agonist for the treatment of general anxiety disorder (GAD). Synonyms: N-(4-((Methylamino)methyl)phenyl)-4-oxo-4,5,6,7-tetrahydro-1H-indole-3-carboxamide hydrochloride; 1H-Indole-3-carboxamide, 4,5,6,7-tetrahydro-N-[4-[(methylamino)methyl]phenyl]-4-oxo-, hydrochloride (1:1). Grade: ≥95%. CAS No. 225240-86-8. Molecular formula: C17H20ClN3O2. Mole weight: 333.81.
CP 412065
It is originally isolated from Hericium ramosum CL 24240. CP 412065 selectively inhibited κ-opioid receptor binding with IC50 > 200 μnmol/L. Synonyms: Antibiotic CP 412065. Molecular formula: C25H34O6. Mole weight: 430.53.
CP 424174
CP 424174 has been found to be an inhibitor of stimulus-coupled IL-1β post-translational processing. Synonyms: CP-424174; CP 424174; CP424174; CP-424,174; CP 424,174; CP424,174; N-[[[4-Chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)benzenesulfonamide. Grade: ≥98% by HPLC. CAS No. 210825-31-3. Molecular formula: C22H29ClN2O4S. Mole weight: 452.99.
CP-457677, also called as TX006169, is a JNK inhibitor. Synonyms: 2-(4-fluorophenoxy)-N-[[4-(2-hydroxypropan-2-yl)phenyl]methyl]pyridine-3-carboxamide; CP-457677; CP457677; CP 457677; UNII-5A83419M4U. Grade: >98%. CAS No. 214535-77-0. Molecular formula: C22H21FN2O3. Mole weight: 380.41.
CP-457920
CP-457920, also called as NGD 971, is a selective α5 GABAA receptor inverse agonist (Ki of ~ 1 ng/mL). CP-457920 was progressed into clinical studies for the treatment of Vascular dementia but discontinued. Synonyms: N-benzyl-6-ethoxy-4-oxo-1H-1,5-naphthyridine-3-carboxamide; CP-457920; CP457920; CP 457920; UNII-13BME2F602; CP-457,920. Grade: >98%. CAS No. 220860-50-4. Molecular formula: C18H17N3O3. Mole weight: 323.35.
CP 461
CP 461, belonging to a class of novel proapoptotic drugs with antineoplastic effect, specifically inhibit cyclic GMP phosphodiesterases but not cyclooxygenase-1 or -2. Synonyms: CP 461; CP-461; CP461; OSI 461; UNII-68OJX9I7DT. N-benzyl-2-[6-fluoro-2-methyl-3-(pyridin-4-ylmethylidene)inden-1-yl]acetamide; hydrochloride; CAS: 227619-92-3 (CP-461 free base). Grade: >98%. CAS No. 227619-96-7. Molecular formula: C25H22ClFN2O. Mole weight: 420.91.
CP-461 free base
CP 461, belonging to a class of novel proapoptotic drugs with antineoplastic effect, specifically inhibit cyclic GMP phosphodiesterases but not cyclooxygenase-1 or -2. Synonyms: CP-461 free base; CP 461 free base; CP461 free base; N-benzyl-2-[(3Z)-6-fluoro-2-methyl-3-(pyridin-4-ylmethylidene)inden-1-yl]acetamide; UNII-824ZMS3BGL; OSI-461 free base. Grade: >98%. CAS No. 227619-92-3. Molecular formula: C25H21FN2O. Mole weight: 384.45.
CP 465022
CP 465022, with anticonvulsant activity, is a potent, brain penetrant, orally active and selective noncompetitive AMPA receptor antagonist (IC50 = 25 nM in rat cortical neurons). CP 465022 provides neuroprotective efficacy after cerebral ischemia on the basis of the activity in experimental ischemia models. Synonyms: 3-(2-chlorophenyl)-2-[2-[6-(diethylaminomethyl)pyridin-2-yl]ethenyl]-6-fluoroquinazolin-4-one; CP-465022; CP 465022; CP465022; UNII-4582JTR93Y. Grade: >99 %. CAS No. 199655-36-2. Molecular formula: C26H24ClFN4O. Mole weight: 499.41.
CP-465022
CP-465022 is a potent, and selective noncompetitive AMPA receptor antagonist with anticonvulsant activity. CP-465022 is against Kainate-induced response with an IC 50 of 25 nM in rat cortical neurons. CP-465022 provides a new tool to investigate the role of AMPA receptors in physiological and pathophysiological processes [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 199655-36-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-18663.
CP 465022 hydrochloride
CP 465022 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 199655-36-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CP-465022 hydrochloride
CP-465022 hydrochloride, a potent, selective and non-competitive AMPA receptor antagonist with anticonvulsant activity, is against Kainate-induced response with an IC50 of 25 nM in rat cortical neurons. Synonyms: 3-(2-Chlorophenyl)-2-[(E)-2-{6-[(diethylamino)methyl]pyridin-2-yl}vinyl]-6-fluoroquinazolin-4(3H)-one hydrochloride (1:1); 4(3H)-Quinazolinone, 3-(2-chlorophenyl)-2-[(E)-2-[6-[(diethylamino)methyl]-2-pyridinyl]ethenyl]-6-fluoro-, hydrochloride (1:1); (E)-3-(2-chlorophenyl)-2-(2-(6-((diethylamino)methyl)pyridin-2-yl)vinyl)-6-fluoroquinazolin-4(3H)-one hydrochloride. CAS No. 1785666-59-2. Molecular formula: C26H25Cl2FN4O. Mole weight: 499.41.
CP 46665 is Immunomodulator. But it is lack of therapeutic activity in rodent tumors and human non-seminomatous germ cell tumors growing in nude mice. Uses: Anti-tumor. Synonyms: CP 46665; CP46665; CP-46665; CP-46,665. 4-Aminomethyl-1-(2,3-bis(decyloxy)propyl)-4-phenylpiperidine. Grade: 98%. CAS No. 72618-10-1. Molecular formula: C35H66Cl2N2O2. Mole weight: 617.82.
CP-466722 is a potent and reversible ATM inhibitor, does not affect ATR and inhibits PI3K or PIKK family members in cells. Synonyms: CP-466722; CP 466722; CP466722. Grade: >98%. CAS No. 1080622-86-1. Molecular formula: C17H15N7O2. Mole weight: 349.35.
CP-467688
CP-467688 is a microsomal triglyceride transfer protein inhibitor used in atherosclerosis therapy. Synonyms: methyl N-[2-[6-[[2-[4-(trifluoromethyl)phenyl]benzoyl]amino]-3,4-dihydro-1H-isoquinolin-2-yl]ethyl]carbamate; hydrochloride; 909576-25-6 (CP-467688); CP 467688; CP467688; 208590-81-2 (CP-467688 free base). Grade: >98%. CAS No. 208590-81-2. Molecular formula: C27H27ClF3N3O3. Mole weight: 533.97.
CP 471474
CP 471474 a broad spectrum Matrix Metalloprotease inhibitor with sub-nanomolar affinity for MMP-2 and 13 among MMPs (IC50: 1170, 0.7, 16, 13, 0.9 for MMP-1, MMP-2, MMP-3, MMP-9, and MMP-13 respectively). Synonyms: CP-471474; CP 471474; CP471474; UNII-96U47H947L; 2-[[4-(4-fluorophenoxy)phenyl]sulfonylamino]-N-hydroxy-2-methylpropanamide; CP 471474; CP-471474; 210755-45-6; CHEMBL323612. Grade: >97 %. CAS No. 210755-45-6. Molecular formula: C16H17FN2O5S. Mole weight: 368.38.
A broad spectrum inhibitor of matrix metalloproteinases that attenuates early left ventricular dilation after experimental myocardial infarction in mice. Studies show that it also inhibits cigarette smoke-induced lung inflammation and the progression of emphysema in guinea pig models. Group: Biochemicals. Alternative Names: 2-[[[4- (4-Fluorophenoxy) phenyl]sulfonyl]amino]-N-hydroxy-2-methylpropanamide; CP 471474. Grades: Highly Purified. CAS No. 210755-45-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
CP-472555
CP-472555 is an effective Glucocorticoid receptor agonist and probably has steroid-like anti-inflammatory properties with anti-GR and anti-obesity activity in animal models. Uses: Glucocorticoid receptor antagonists. Synonyms: CP-472555; CP 472555; CP472555; UNII-6T0KV7024R. 2-Phenanthrenecarboxamide, 4b,5,6,7,8,8a,9,10-octahydro-7-hydroxy-4b-(phenylmethyl)-7-(1-propyn-1-yl)-N-(3-pyridinylmethyl)-, (4bS,7R,8aR)-. Grade: ≥95%. CAS No. 305821-96-9. Molecular formula: C31H32N2O2. Mole weight: 464.24.
CP-47947
CP-47947. Group: Biochemicals. Alternative Names: rel-5- (1, 1-dimethylheptyl) -2- [ (1R, 3S) -3-hydroxycyclohexyl] phenol; (+/-)-CP 47497; CP 47947. Grades: Highly Purified. CAS No. 70434-82-1. Pack Sizes: 1mg, 2mg. Molecular Formula: C21H34O2. US Biological Life Sciences.
Worldwide
CP-47947 Benzyl Ether
CP-47947 derivative. A cannabinoid receptor ligand. Group: Biochemicals. Alternative Names: cis-3-[4-(1,1-Dimethylheptyl)-2-(phenylmethoxy)phenyl]-cyclohexanol. Grades: Highly Purified. CAS No. 70434-49-0. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
CP-481715
CP-481715 is a potent and selective CCR1 antagonist with >100-fold selective for CCR1 as compared with a panel of G-protein-coupled receptors including related chemokine receptors. CP-481,715 inhibits cell infiltration and inflammatory responses in human CCR1 transgenic mice. Synonyms: N-[(2S,3S,5R)-5-carbamoyl-1-(3-fluorophenyl)-3,8-dihydroxy-8-methylnonan-2-yl]quinoxaline-2-carboxamide; CP 481,715; CP 481715; CP-481,715; CP-481715; CP481,715; CP481715; quinoxaline-2-carboxylic acid (4-carbamoyl-1-(3-fluorobenzyl)-2,7-dihydroxy-7-methyloctyl)amide. Grade: >98%. CAS No. 212790-31-3. Molecular formula: C26H31FN4O4. Mole weight: 482.55.
Cp4G
Cp4G, an invaluable compound extensively used in the biomedical sector to study G protein-coupled receptors (GPCRs) is bestowed with unmatched affinity towards GPR120, a receptor that holds immense therapeutic promise to combat obesity and type 2 diabetes. Having demonstrated pronounced efficacy, Cp4G presents an exciting avenue for drug development in the fight against these rampant maladies. Synonyms: P1- (5'- Cytidyl)- P4- (5'- guanosyl)- tetraphosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 79695-24-2. Molecular formula: C19H28N8O21P4 (free acid). Mole weight: 828.4 (free acid).
CP-5068
CP-5068 is a synthetic bio-active chemical. Uses: A synthetic bio-active chemical. Synonyms: CP-5068; CP 5068; CP5068; UNII-0UZY88DX6N. (4S,5R,6S)-3-[6-(2-amino-2-oxoethyl)-7-methylsulfanylimidazo[5,1-b][1,3]thiazol-6-ium-2-yl]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate. Grade: ≥98%. CAS No. 352305-79-4. Molecular formula: C18H20N4O5S2. Mole weight: 436.08.
CP-532623, structurally related to Torcetrapib, is a potent inhibitor of cholesteryl ester transfer protein (CETP). Synonyms: CP-532623; CP 532623; CP532623; UNII-5KK52HG8D; 10-[3-(4-hydroxypiperidin-1-yl)propyl]phenothiazine-2-carbonitrile. Grade: >98%. CAS No. 261947-38-0. Molecular formula: C27H27F9N2O3. Mole weight: 598.5.
CP-533536
CP-533536, also called as Evatanepag, a 3-pyridyl sulfonamide compound, demonstrated excellent in vitro potency against prostaglandin E2 (PGE2) (induces local bone formation with EC50= 0.3 nM) and selectivity against a broad panel of other targets. Synonyms: 2-[3-[[(4-tert-butylphenyl)methyl-pyridin-3-ylsulfonylamino]methyl]phenoxy]acetic acid(3-((4-tert-butylbenzyl)-(pyridine-3-sulfonylamino)methyl)phenoxy)acetic acidCP-533536; CP 533536; CP533536; Evatanepag. Grade: 95%. CAS No. 223488-57-1. Molecular formula: C25H28N2O5S. Mole weight: 468.56.
CP-53631
CP-53631 is a selective serotonin reuptake inhibitor (SSRI); antidepressant. Group: Biochemicals. Alternative Names: (1R,4S)-rel-4-(4-Bromophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine Hydrochloride; trans-4-(4-Bromophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine Hydrochloride; trans-(±)-4-(4-Bromophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine Hydrochloride. Grades: Highly Purified. CAS No. 79836-56-9. Pack Sizes: 10mg. US Biological Life Sciences.
CP 544326, also known as taprenepag, is a potent and selective EP(2) receptor agonist. Its EC50 value is 2.8 nM. It is the active acid metabolite of the prodrug PF-04217329. It was successfully evaluated for its ocular hypotensive activity in a clinical study involving patients with primary open angle glaucoma. Uses: Cp 544326 was successfully evaluated for its ocular hypotensive activity in a clinical study involving patients with primary open angle glaucoma. Synonyms: CP-544326; CP544326, CP544326, Taprenepag, PF-0421732 metabolite; 2-(3-((N-(4-(1H-pyrazol-1-yl)benzyl)pyridine-3-sulfonamido)methyl)phenoxy)acetic acid; CP-544326; CP544326; CP544326; Taprenepag; PF-0421732 metabolite. Grade: 98%. CAS No. 752187-80-7. Molecular formula: C24H22N4O5S. Mole weight: 478.52.
CP-544439
CP-544439 is a selective matrix metalloproteinase-13 inhibitor. Uses: Matrix metalloproteinase inhibitors. Synonyms: 4-[[4-(4-fluorophenoxy)phenyl]sulfonylamino]-N-hydroxyoxane-4-carboxamide; CP-544439; CP 544439; CP544439 ; UNII-516DO4KL5R. Grade: >98%. CAS No. 230954-09-3. Molecular formula: C18H19FN2O6S. Mole weight: 410.42.
CP-547632
CP-547632 is as a potent inhibitor of the VEGFR-2 and basic fibroblast growth factor (FGF) kinases (IC50 11 and 9 nM, respectively). It is selective relative to epidermal growth factor receptor, platelet-derived growth factor , and other related TKs. It also inhibits VEGF-stimulated autophosphorylation of VEGFR-2 in a whole cell assay with an IC50 value of 6 nM. After oral administration of CP-547,632 to mice bearing NIH3T3/H-ras tumors, VEGFR-2 phosphorylation in tumors was inhibited in a dose-dependent fashion (EC50 590 ng/ml). CP-547,632 is a well-tolerated, orally-bioavailable inhibitor presently under clinical investigation for the treatment of human malignancies. Synonyms: CP547632; CP 547632; CP-547632; PAN90806; PAN 90806; PAN-90806; CP632; OSI632; CP 632; OSI 632; CP-632; OSI-632. CAS No. 252003-65-9. Molecular formula: C20H24BrF2N5O3S. Mole weight: 532.405.
CP-547632 hydrochloride
CP-547632 hydrochloride is a potent, orally active and ATP-competitive inhibitor of VEGFR-2 and FGF kinases with IC50s of 11 and 9 nM, respectively. It is selective for VEGFR2 and bFGF over EGFR, PDGFRβ and related tyrosine kinases (TKs). It has antitumor effect. Synonyms: 3-[(4-Bromo-2,6-difluorophenyl)methoxy]-5-[[[[4-(1-pyrrolidinyl)butyl]amino]carbonyl]amino]-4-Isothiazolecarboxamide hydrochloride; PF-01371182 hydrochloride; 3-[(4-Bromo-2,6-difluorobenzyl)oxy]-5-({[4-(1-pyrrolidinyl)butyl]carbamoyl}amino)-1,2-thiazole-4-carboxamide hydrochloride (1:1); 4-Isothiazolecarboxamide, 3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-[[[[4-(1-pyrrolidinyl)butyl]amino]carbonyl]amino]-, hydrochloride (1:1). Grade: ≥98%. CAS No. 252003-71-7. Molecular formula: C20H25BrClF2N5O3S. Mole weight: 568.86.
CP-547632 hydrochloride
CP-547632 hydrochloride is an orally active, ATP-competitive and potent VEGFR-2 and FGF kinases inhibitor with IC50s of 11 nM and 9 nM, respectively. CP-547632 hydrochloride is selective for VEGFR2 and bFGF over EGFR, PDGFR?, and related tyrosine kinases (TKs). CP-547632 hydrochloride has antitumor efficacy[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 252003-71-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13302B.