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| Product | Description | |
|---|---|---|
| Ezetimibe Diacetate | Protected Ezetimibe derivative. Group: Biochemicals. Alternative Names: (3R,4S)-. Grades: Highly Purified. CAS No. 163380-20-9. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| Ezetimibe (Diacid Impurity) | An open-ringed diacid impurity of Ezetimibe. Group: Biochemicals. Alternative Names: (2R) -2- [ (S) - [ (4-Fluorophenyl) amino] [4- (phenylmethoxy) phenyl] methyl] pentanedioic Acid. Grades: Highly Purified. CAS No. 1013025-04-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Ezetimibe Diacid Impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: ( (2R, 3S) -2-[ (4-Benzyloxyphenyl) -4- (4-Fluorophenylamino) methyl]pentanedioic acid). Grades: > 95%. CAS No. 1013025-04-1. Molecular formula: C25H24FNO5. Mole weight: 437.47. |  |
| Ezetimibe Diol | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L22) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (1S,4R)-1-(4-Fluorophenyl)-4-[(S)-[(4-fluorophenyl)amino](4-hydroxyphenyl)methyl]-1,5-pentanediol. Grades: > 95%. CAS No. 1374250-08-4. Molecular formula: C24H25F2NO3. Mole weight: 413.47. | |
| Ezetimibe Fluoro Isomer | A stereoisomer of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L9) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 3'-(2-Fluorophenyl) Ezetimibe; (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(2-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone. Grades: > 95%. CAS No. 1798008-25-9. Molecular formula: C24H21F2NO3. Mole weight: 409.44. | |
| Ezetimibe hydroxy-D-glucuronide D4 | Ezetimibe hydroxy-D-glucuronide D4 is a metabolite of stable isotope-labeled Ezetimibe, playing a profound role in illuminating the intricate mechanisms of Ezetimibe metabolism, pharmacokinetics and elimination pathways. Molecular formula: C30H25D4F2NO9. Mole weight: 589.57. | |
| Ezetimibe Hydroxy Glucuronide | A metabolite of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: Ezetimibe Hydroxy β-D-Glucuronide; (1S)-1-(4-Fluorophenyl)-3-[(2S,3R)-1-(4-fluorophenyl)-2-(4-hydroxyphenyl)-4-oxo-3-azetidinyl]propyl β-D-Glucopyranosiduronic Acid. Grades: > 95%. CAS No. 536709-33-8. Molecular formula: C30H29F2NO9. Mole weight: 585.55. | |
| Ezetimibe Hydroxy tert-Butyldiphenylsilyl Ether | Ezetimibe Hydroxy tert-butyldiphenylsilyl ether is a substituted Ezetimibe. Group: Biochemicals. Alternative Names: (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-tert-butyldiphenylsilyloxy-3-(4-fluorophenyl)propyl]-4-(4-hydroxyphenyl)-2-azetidinone. Grades: Highly Purified. CAS No. 1217748-67-8. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Ezetimibe Impuriry 66 | Ezetimibe Impuriry 66. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1044664-24-5. Molecular formula: C26H23F2NO4. Mole weight: 451.47. Catalog: APB1044664245. |  |
| Ezetimibe Impuriry 74 | Ezetimibe Impuriry 74. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1683564-73-9. Molecular formula: C31H27F2NO3. Mole weight: 499.56. Catalog: APB1683564739. | |
| Ezetimibe Impuriry 75 | Ezetimibe Impuriry 75. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1416263-36-9. Molecular formula: C31H27F2NO3. Mole weight: 499.56. Catalog: APB1416263369. | |
| Ezetimibe Impuriry 82 | Ezetimibe Impuriry 82. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1683564-75-1. Molecular formula: C31H27F2NO3. Mole weight: 499.56. Catalog: APB1683564751. | |
| Ezetimibe Impurity 10 | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L44) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4R)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one. Grades: > 95%. Molecular formula: C18H18FNO3. Mole weight: 315.35. | |
| Ezetimibe Impurity 2 | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L17) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4S)-4-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(3-oxo-3-phenylpropyl)azetidin-2-one. Grades: > 95%. Molecular formula: C31H26FNO3. Mole weight: 479.56. | |
| Ezetimibe Impurity 3 | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L18) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4S)-4-(4-(benzyloxy)phenyl)-3-(3-(4-fluorophenyl)-3-oxopropyl)-1-phenylazetidin-2-one. Grades: > 95%. Molecular formula: C31H26FNO3. Mole weight: 479.56. | |
| Ezetimibe impurity (3-[5-(4-Fluoro-phenyl)-5-(R)-hydroxy-pentanoyl]-4-(R)-phenyl-oxazolidin-2-one) | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L38) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (4R)-4-Phenyl-3-[(5R)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-1,3-oxazolidin-2-one. Grades: > 95%. Molecular formula: C20H20FNO4. Mole weight: 357.39. | |
| Ezetimibe impurity (3-[5-(4-Fluoro-phenyl)-5-(R)-hydroxy-pentanoyl]-4-(S)-phenyl-oxazolidin-2-one) | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L36) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (S)-3-((R)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one. Grades: > 95%. CAS No. 528565-93-7. Molecular formula: C20H20FNO4. Mole weight: 357.39. | |
| Ezetimibe impurity (3-[5-(4-Fluoro-phenyl)-5-(S)-hydroxy-pentanoyl]-4-(R)-phenyl-oxazolidin-2-one) | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L37) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (4R)-4-Phenyl-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-1,3-oxazolidin-2-one. Grades: > 95%. CAS No. 189028-95-3. Molecular formula: C20H20FNO4. Mole weight: 357.39. | |
| Ezetimibe impurity (3-[5-(4-Fluoro-phenyl)-5-(S)-hydroxy-pentanoyl]-4-(S)-phenyl-oxazolidin-2-one) | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L39) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (4S)-4-Phenyl-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-1,3-oxazolidin-2-one. Grades: > 95%. Molecular formula: C20H20FNO4. Mole weight: 357.39. | |
| Ezetimibe Impurity 38 | Ezetimibe Impurity 38. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-3-((2R,5S)-5-((tert-butyldimethylsilyl)oxy)-2-((S)-(4-((tert-butyldimethylsilyl)oxy)phenyl)((4-fluorophenyl)amino)methyl)-5-(4-fluorophenyl)pentanoyl)-4-phenyloxazolidin-2-one. CAS No. 1701462-59-0. Molecular formula: C45H58F2N2O5Si2. Mole weight: 801.12. Catalog: APB1701462590. | |
| Ezetimibe Impurity 39 | Ezetimibe Impurity 39. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-hydroxybenzaldehyde. CAS No. 123-08-0. Molecular formula: C7H6O2. Mole weight: 122.12. Catalog: APB123080. | |
| Ezetimibe Impurity 4 | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L19) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3S,4R)-4-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-oxopropyl)azetidin-2-one. Grades: > 95%. Molecular formula: C31H25F2NO3. Mole weight: 497.55. | |
| Ezetimibe Impurity 49 | Ezetimibe Impurity 49. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: dihydro-2H-pyran-2,6(3H)-dione. CAS No. 108-55-4. Molecular formula: C5H6O3. Mole weight: 114.1. Catalog: APB108554. | |
| Ezetimibe Impurity 5 | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L20) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4R)-4-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-hydroxypropyl)azetidin-2-one. Grades: > 95%. Molecular formula: C31H27F2NO3. Mole weight: 499.56. | |
| Ezetimibe Impurity 8 | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L42) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (S)-1-(4-fluorophenyl)-5-(2-oxo-4-phenyloxazolidin-3-yl)pentane-1,5-dione. Grades: > 95%. CAS No. 189028-93-1. Molecular formula: C20H18FNO4. Mole weight: 355.37. | |
| Ezetimibe Impurity 8 Enantiomer | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L46) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 3-[5-(1,5-Dioxo-5-(p-fluophenylpentyl]-4R-phenyl-2-oxazolidinone. Grades: > 95%. CAS No. 404874-93-7. Molecular formula: C20H18FNO4. Mole weight: 355.37. | |
| Ezetimibe Impurity 9 | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L43) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (S)-3-((2R,5S)-5-(4-Fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-((trimethylsilyl)oxy)phenyl)methyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one; 3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl(amino)]][4-[trimethylsilyl]-oxy]phenyl]methyl]-1-oxo-5-[(trimethylsily)-oxy]pentyl]-4-phenyl-(4S)-2-oxazolidinone. Grades: > 95%. CAS No. 272778-12-8. Molecular formula: C39H46F2N2O5Si2. Mole weight: 716.98. | |
| Ezetimibe Impurity B | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L14) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: methyl 5-(4-fluorophenyl)-5-hydroxypentanoate. Grades: > 95%. CAS No. 870634-36-9. Molecular formula: C12H15FO3. Mole weight: 226.25. | |
| Ezetimibe Impurity G | Ezetimibe Impurity G. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3R,4S)-1-(3-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one. CAS No. 1700622-06-5. Molecular formula: C24H21F2NO3. Mole weight: 409.43. Catalog: APB1700622065. | |
| Ezetimibe Impurity I | Ezetimibe Impurity I. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3R,4S)-1-(4-fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one. CAS No. 1700622-07-6. Molecular formula: C25H24FNO3. Mole weight: 405.46. Catalog: APB1700622076. | |
| Ezetimibe Impurity J | Ezetimibe Impurity J. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one. CAS No. 1700622-08-7. Molecular formula: C24H21ClFNO3. Mole weight: 425.88. Catalog: APB1700622087. | |
| Ezetimibe Impurity L | Ezetimibe Impurity L. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-N,5-bis(4-fluorophenyl)-2-(4-hydroxybenzyl)pentanamide. CAS No. 1510820-22-0. Molecular formula: C24H23F2NO2. Mole weight: 395.44. Catalog: APB1510820220. | |
| Ezetimibe Impurity (Tetrahydro-pyran-2-one) | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L35) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,6R)-6-(4-fluorophenyl)-3-((S)-((4-fluorophenyl)amino)(4-hydroxyphenyl)methyl)tetrahydro-2H-pyran-2-one. Grades: > 95%. Molecular formula: C24H21F2NO3. Mole weight: 409.44. | |
| Ezetimibe ketone | Ezetimibe ketone. Group: Biochemicals. Alternative Names: (3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)-2-azetidinone; EZM-K. Grades: Highly Purified. CAS No. 191330-56-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C24H19F2NO3. US Biological Life Sciences. | Worldwide |
| Ezetimibe ketone | Ezetimibe ketone (EZM-K) is a phase-I metabolite of Ezetimibe. Ezetimibe is a Niemann-Pick C1-like1 ( NPC1L1 ) inhibitor, and is a potent Nrf2 activator. Ezetimibe is a potent cholesterol absorption inhibitor [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EZM-K. CAS No. 191330-56-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-133114. |  |
| Ezetimibe Ketone | Phase-I metabolite of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)-2-azetidinone. Grades: > 95%. CAS No. 191330-56-0. Molecular formula: C24H19F2NO3. Mole weight: 407.42. | |
| Ezetimibe Lactam Cleaved Alcohol | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L23) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 3'-Anhydro Ezetimibe Alcohol Impurity; (βR,γS)-γ-[(4-Fluorophenyl)amino]-β-[3-(4-fluorophenyl)-2-propen-1-yl]-4-hydroxybenzenepropanol. Grades: > 95%. CAS No. 1374250-07-3. Molecular formula: C24H23F2NO2. Mole weight: 395.45. | |
| Ezetimibe Phenexy Glucuronide | A metabolite of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: Ezetimibe phenoxy Glucuronide. Grades: > 95%. CAS No. 190448-57-8. Molecular formula: C30H29F2NO9. Mole weight: 585.55. | |
| Ezetimibe phenoxy glucuronide | Ezetimibe phenoxy glucuronide (Ezetimibe glucuronide) is the active metabolite of Ezetimibe. Antihyperlipoproteinemic activity [1]. Ezetimibe is a potent cholesterol absorption inhibitor [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ezetimibe glucuronide; Ezetimibe β-D-glucuronide. CAS No. 190448-57-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-135391. | |
| Ezetimibe Phenoxy tert-Butyldiphenylsilyl Ether | Ezetimibe Phenoxy tert-butyldiphenylsilyl ether is a substituted Ezetimibe. Group: Biochemicals. Alternative Names: (3R, 4S) -1- (4-Fluorophenyl ) -3- [ (3S) -3- (4-fluorophenyl ) -3- hydroxypropyl ] -4- (4-tert-butyl diphenyl silyl oxyphenyl ) -2-azetidinone. Grades: Highly Purified. CAS No. 1042722-66-6. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Ezetimibe Related Impurity 6 | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L40) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4R)-1-(3-fluorophenyl)-3-((S)-3-(3-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one. Grades: > 95%. Molecular formula: C24H21F2NO3. Mole weight: 409.44. | |
| Ezetimibe Related Impurity 7 | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L41) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4R)-1-(3-fluorophenyl)-3-((E)-3-(3-fluorophenyl)allyl)-4-(4-hydroxyphenyl)azetidin-2-one. Grades: > 95%. CAS No. 204589-68-4. Molecular formula: C24H19F2NO2. Mole weight: 391.42. | |
| Ezetimibe Ring-Open Impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L15) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: 2-(4-Hydroxybenzyl)-N,5-bis-(4-fluorophenyl)-5-hydroxypentanamide. Grades: > 95%. CAS No. 1197811-72-5. Molecular formula: C24H23FNO3. Mole weight: 411.45. | |
| Ezetimibe ring-opening dehydrate impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L31) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (αR,βS)-β-[(4-Fluorophenyl)amino]-α-[3-(4-fluorophenyl)-2-propen-1-yl]-4-hydroxybenzenepropanoic Acid. Grades: > 95%. CAS No. 1292292-63-7. Molecular formula: C24H21F2NO3. Mole weight: 409.44. | |
| Ezetimibe System Suitability Mixture | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Ezetimibe Tetrahydropyran Impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (2R,3R,6S)-N,6-Bis(4-fluorophenyl)tetrahydro-2-(4-hydroxyphenyl)-2H-pyran-3-carboxamide; SCH59566. Grades: > 95%. CAS No. 1296129-15-1. Molecular formula: C24H21F2NO3. Mole weight: 409.44. | |
| Ezetimibe Triol Impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L48) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: (3R,4R,5R)-3-(4-fluorophenyl)-5-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-1-((S)-2-hydroxy-1-phenylethyl)-4-(4-hydroxyphenyl)piperidine-2,6-dione. Grades: > 95%. Molecular formula: C33H30F2N2OS. Mole weight: 572.61. | |
| EZH1/EED/SUZ12 human | recombinant, expressed in baculovirus infected insect cells. Group: Fluorescence/luminescence spectroscopy. | |
| EZH1/EED/SUZ12/RbAp48/AEBP2 human | recombinant, expressed in baculovirus infected insect cells, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| EZH2/EED inactive human | recombinant, expressed in baculovirus infected insect cells, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| EZH2 / EED / SUZ12 human | recombinant, expressed in baculovirus infected insect cells, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| EZH2/EED/SUZ12/RbAp48 active human | recombinant, expressed in baculovirus infected Sf9 cells, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| EZH2/EED/SUZ12/RbAp48/AEBP2 human | recombinant, expressed in baculovirus infected insect cells. Group: Fluorescence/luminescence spectroscopy. | |
| EZH2 human | recombinant, expressed in baculovirus infected Sf9 cells, ?49% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| EZH2-IN-14 | EZH2-IN-14 is a selective EZH2 ( Histone Methyltransferase ) inhibitor with an IC 50 of 12 nM. EZH2-IN-14 inhibits the methyltransferase activity of EZH2/PRC2 (that is, reducing H3K27me3). EZH2-IN-14 shows >200-fold selective for EZH2 over the highly homologous H3K27 methyltransferase EZH1 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1979157-17-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148458. | |
| Ezh2 Inhibitor II, EI1(Enhancer of Zested Homolog 2 Inhibitor II, HMTase Inhibitor XI, 6-Cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide) | A cell-permeable indolocarboxamide compound that acts as a potent and selective inhibitor against Ezh2/PRC2 (Polycomb repressive complex 2; Ezh2 / SUZ12 / EED / AEBP2 / RbAP48) HMTase activity (IC50/substrate = 15nM/H3K27me021-44 and 13nM/H3K27me221-44, respectively, against human wt or Y641F Ezh2-containing PRC2; [SAM] = 1uM) in a cofactor SAM-competitive manner, while inhibiting Ezh1/PRC2 only at much higher concentrations (IC50 = 1.34uM) and exhibiting no potency toward CARM 1, Dot1L, G9a, MLL, NSD3, Set7/9, SETD2, SETD8, SmyD2, or Suv39H2 (IC50 >100uM). Shown to suppress cellular H3K27 dimethylation and trimethylation (1 to 10uM) in DLBCL cultures and exhibit antiproliferation activity against DLBCL cell lines with wt or mutant Ezh2 (3.3uM to 10uM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?, Primary Target: Ezh2/PRC2. US Biological Life Sciences. | Worldwide |
| EZH2/SUZ12/RbAp48 human | recombinant, expressed in baculovirus infected Sf9 cells, ?88% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| Ezlopitant | Ezlopitant, also known as CJ-11,974, is a NK1 receptor antagonist. It has antiemetic and antinociceptive effects. Synonyms: CJ 11,974; CJ-11974; CJ11974; (7S,8S)-7-[di(phenyl)methyl]-N-[(2-methoxy-5-propan-2-ylphenyl)methyl]-1-azabicyclo[2.2.2]octan-8-amine. CAS No. 147116-64-1. Molecular formula: C31H38N2O. Mole weight: 454.66. | |
| EZM0414 | EZM0414 is a potent, selective, orally bioavailable inhibitor of SETD2 (IC50=18 nM in SETD2 biochemical assay; IC50=34 nM in cellular assay). EZM0414 can be used for the research of relapsed or refractory multiple myeloma and diffuse large B-cell lymphoma[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2411748-50-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144858. | |
| EZM0414 TFA | EZM0414 (SETD2-IN-1) TFA is the TFA salt form of EZM0414 (HY-144858). EZM0414 TFA is a potent, selective, orally active inhibitor of SETD2 (IC50=18 nM in SETD2 biochemical assay; IC50=34 nM in cellular assay). EZM0414 TFA can be used for the research of relapsed or refractory multiple myeloma and diffuse large B-cell lymphoma[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SETD2-IN-1 TFA. CAS No. 2411759-92-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136328. | |
| EZM 2302 | EZM 2302 is a potent and orally active CARM1 inhibitor with an IC50 value of 6 nM. EZM 2302 shows antiproliferative activity and anti-tumor activity. EZM 2302 inhibits PABP1 and SMB expression[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1628830-21-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111109. | |
| EZM 2302 | EZM 2302 Inhibitor. Uses: Scientific use. Product Category: T5605. CAS No. 1628830-21-6. |  |
| Ezomycin A1 | Ezomycin A1 is an antifungal antibiotic produced by Streptomyces kitazawaensis 009. It is mainly active against phytopathogens such as Sclerotinia sclerotiorum and Botrytis, and has a control effect on sclerotinia, botrytis and candidiasis of crops. CAS No. 39422-19-0. Molecular formula: C26H38N8O15S. Mole weight: 734.69. | |
| Ezomycin A2 | Ezomycin A2 is an antifungal antibiotic produced by Streptomyces kitazawaensis 009. It is mainly active against phytopathogens such as Sclerotinia sclerotiorum and Botrytis, and has a control effect on sclerotinia, botrytis and candidiasis of crops. CAS No. 54328-22-2. Molecular formula: C19H26N6O12. Mole weight: 530.44. | |
| Ezomycin B2 | Ezomycin B2 is an antifungal antibiotic produced by Streptomyces kitazawaensis 009. It is mainly active against phytopathogens such as Sclerotinia sclerotiorum and Botrytis, and has a control effect on sclerotinia, botrytis and candidiasis of crops. CAS No. 57973-16-7. Molecular formula: C19H25N5O13. Mole weight: 531.43. | |
| Ezomycin D2 | Ezomycin D2 is an antifungal antibiotic produced by Streptomyces kitazawaensis 009. It is mainly active against phytopathogens such as Sclerotinia sclerotiorum and Botrytis, and has a control effect on sclerotinia, botrytis and candidiasis of crops. CAS No. 57973-11-2. Molecular formula: C19H27N5O14. Mole weight: 549.44. | |
| Ezrin Inhibitor, NSC668394 (7- (3, 5-dibromo-4-hydroxyphenethylamino) quinoline-5, 8-dione) | A cell-permeable, quinoline that binds directly to ezrin (=12.6uM) in a reversible manner, and inhibits PKC?-mediated ezrin phosphorylation at Thr567 (IC50=8.1uM) and ezrin-actin binding, in vitro. It also inhibits murine osteosarcoma K7M2 cell invasion in a monolayer of HUVEC cells, dose-dependently, from 1 to 10uM. At 10uM, it causes a unique developmental defect in zebrafish, characterized by reduced motility of eye progenitor cells. Furthermore, this small molecule prevents metastatic growth in an ex vivo mouse lung organ culture assay at 10uM and attenuates ezrin-dependent OS metastatic growth in mouse lung model in vitro at 2.26mg/kg/day. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| E,Z-trans-3-(2-Chloroethenyl)-2,2-dimethyl-cyclopropanecarboxylic Acid | E,Z-trans-3-(2-Chloroethenyl)-2,2-dimethyl-cyclopropanecarboxylic Acid is the photolysis product of Permethrin, which is a medication and an insecticide used to treat scabies and lice. Synonyms: E,Z-trans-3-(2-Chlorovinyl)-2,2-dimethylcyclopropanecarboxylic Acid; Cyclopropanecarboxylic acid, 3-[(1E)-2-chloroethenyl]-2,2-dimethyl-, (1R,3S)-rel-; rel-(1R,3S)-3-((E)-2-chlorovinyl)-2,2-dimethylcyclopropane-1-carboxylic acid; Cyclopropanecarboxylic acid, 3-(2-chloroethenyl)-2,2-dimethyl-, [1α,3β(E)]-. Grades: 98%. CAS No. 61914-45-2. Molecular formula: C8H11ClO2. Mole weight: 174.62. | |
| Ezurpimtrostat | Ezurpimtrostat is a palmitoyl protein thioesterase 1 (PPT-1) inhibitor. Synonyms: 4-(4-(tert-butylamino)piperidin-1-yl)-N-(4-chlorobenzyl)quinolin-2-amine. CAS No. 1914148-72-3. Molecular formula: C25H31ClN4. Mole weight: 423.00. | |
| Ezurpimtrostat hydrochloride | Ezurpimtrostat hydrochloride (compound 2-3) is a potent and orally active anti-fibrotic agent. Ezurpimtrostat hydrochloride reduces significantly the liver fibrosis in DEN (diethyl nitrosamine) cirrhotic rat model. Ezurpimtrostat hydrochloride can be used for the research of fibrosis, cancer, autophagy and cathepsins B (CTSB), L (CTSL) and D (CTSD) related diseases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GNS561 hydrochloride. CAS No. 1914148-73-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137978A. | |
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