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| Product | Description | |
|---|---|---|
| Everolimus, Cyclosporine and Tacrolimus Mix Standard | Everolimus is a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Cyclosporine is an immunopsupressent thought to bind to cyclophilin in T-lymphocytes. Tacrolimus is also an immunosuppressant that blocks T-cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK-506 binding protein, thereby reversing its effects on sarcoplasmic reticulum Ca+2 release. Molecular formula: C53H83NO14/C62H111N11O12/C44H69N. Mole weight: 958.22/1202.61/612.02. |  |
| Everolimus-d4 | Macrolide immunosuppressant; derivative of Rapamycin. Inhibits cytokine-mediated lymphocyte proliferation. Group: Biochemicals. Alternative Names: 40-O-(2-Hydroxyethyl-d4)rapamycin; 42-O-(2-Hydroxy)ethyl-d4 Rapamycin; Afinitor-d4; Certican-d4; RAD-d4; RAD 001-d4; SDZ-RAD-d4; XIENCE V-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Everolimus-d4 | Everolimus-d 4 is the deuterium labeled Everolimus. Everolimus (RAD001) is a Rapamycin derivative and a potent, selective and orally active mTOR1 inhibitor. Everolimus binds to FKBP-12 to generate an immunosuppressive complex. Everolimus inhibits tumor cells proliferation and induces cell apoptosis and autophagy. Everolimus has potent immunosuppressive and anticancer activities[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: RAD001-d4; SDZ-RAD-d4. CAS No. 1338452-54-2. Pack Sizes: 500 μg. Product ID: HY-10218S. |  |
| Everolimus Dehydrate Impurity | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: Everolimus Dehydro Seco Acid. Grades: > 95%. Molecular formula: C53H83NO14. Mole weight: 958.25. | |
| Everolimus EP Impurity B | Everolimus EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1062122-63-7. Molecular Formula: C53H83NO14. Mole Weight: 958.24. Catalog: APB1062122637. |  |
| Everolimus EP Impurity B (19-Z-Isomer) | Everolimus EP Impurity B (19-Z-Isomer). Uses: For analytical and research use. Group: Impurity standards. CAS No. 763911-41-7. Molecular Formula: C53H83NO14. Mole Weight: 958.24. Catalog: APB763911417. | |
| Everolimus EP Impurity C | Everolimus EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C52H81NO14. Mole Weight: 944.21. Catalog: APB07747. | |
| Everolimus EP Impurity D | Everolimus EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C53H83NO14. Mole Weight: 958.24. Catalog: APB07748. | |
| Everolimus EP Impurity E | Everolimus EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Everolimus EP Impurity E. CAS No. 1237826-25-3. Molecular Formula: C52H79NO14. Mole Weight: 942.18. Catalog: APB1237826253. | |
| Everolimus EP Impurity F | Everolimus EP Impurity F. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Everolimus EP Impurity F. Molecular Formula: C55H89NO16. Mole Weight: 1020.29. Catalog: APB05420. | |
| Everolimus Hydrolized Impurity | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: seco Everolimus B; (2S)-1-[2-[(2R, 3R, 6S)-6-[(2S, 3E, 5E, 7E, 9S, 11R, 13R, 14R, 15E, 17R, 20S, 21R)-14, 20-Dihydroxy-22-[(1S, 3R, 4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2, 13-dimethoxy-3, 9, 11, 15, 17, 21-hexamethyl-12, 18-dioxo-3, 5, 7, 15-docosatetraen-1-yl]tetrahydro-. Grades: > 95%. CAS No. 769905-89-7. Molecular formula: C53H85NO15. Mole weight: 976.27. | |
| Everolimus Impurity 003-09 | Everolimus Impurity 003-09. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Everolimus Impurity 003-09. Molecular Formula: C107H167N2O28. Mole Weight: 1929.47. Catalog: APB05415. | |
| Everolimus Impurity 005-98 | Everolimus Impurity 005-98. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (1R, 9S, 12S, 15R, 16Z, 18R, 19R, 21R, 23S, 24Z, 26Z, 28Z, 30S, 32S, 35R)-1, 18, 30-Trihydroxy-12-{(2R)-1-[(1S, 3R, 4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2-propanyl}-19-methoxy-15, 17, 21, 23, 29, 35-hexamethyl-11, 36 ; -dioxa-4-azatricyclo[30.3.1.0]hexatriaconta-16,24,26. CAS No. 745779-75-3. Molecular Formula: C52H81NO14. Mole Weight: 944.2. Catalog: APB745779753. | |
| Everolimus Impurity 008-96 | Everolimus Impurity 008-96. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Everolimus Impurity 008-96. Molecular Formula: C54H85NO14. Mole Weight: 972.25. Catalog: APB02224. | |
| Everolimus Impurity 012-99 | Everolimus Impurity 012-99. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-(2R,3S,6R,E)-1-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-2,6,8-trimethyl-5,9-dioxonon-7-en-3-yl 1-(2-((2R,3R,6S)-6-((2S,3E,5E,7E,9S,11R)-2,13-dimethoxy-3,9,11-trimethyl-12-oxotrideca-3,5,7-trien-1-yl)-2-hydroxy-3-methyltetrahydro-2H-pyran-2. CAS No. 1708118-13-1. Molecular Formula: C53H83NO14. Mole Weight: 958.22. Catalog: APB1708118131. | |
| Everolimus Impurity 013-99 | Everolimus Impurity 013-99. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-1-(2-((2R,3R,6S)-6-((2S,3E,5E,7E,9S,11R)-2,13-dimethoxy-3,9,11-trimethyl-12-oxotrideca-3,5,7-trien-1-yl)-2-hydroxy-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylic acid. CAS No. 147438-30-0. Molecular Formula: C32H49NO9. Mole Weight: 591.73. Catalog: APB147438300. | |
| Everolimus Impurity 11 | Everolimus Impurity 11. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-((tert-butyldimethylsilyl)oxy)ethyl trifluoromethanesulfonate. Molecular Formula: C9H19F3O4SSi. Mole Weight: 308.39. Catalog: APB05419. | |
| EverolimusImpurity12 | EverolimusImpurity12. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Everolimus Impurity 12. Molecular Formula: C55H87NO15. Mole Weight: 1002.28. Catalog: APB05418. | |
| Everolimus Impurity 13 | Everolimus Impurity 13. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Everolimus Impurity 13. Molecular Formula: C53H83NO14. Mole Weight: 958.22. Catalog: APB05417. | |
| Everolimus Impurity 14 | Everolimus Impurity 14. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Everolimus Impurity 14. Molecular Formula: C53H83NO14. Mole Weight: 958.22. Catalog: APB05416. | |
| Everolimus Impurity 16 | Everolimus Impurity 16. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C53H83NO14. Mole Weight: 958.22. Catalog: APB02225. | |
| Everolimus Impurity 211-97 | Everolimus Impurity 211-97. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Everolimus Impurity 211-97. Molecular Formula: C52H81NO14. Mole Weight: 944.2. Catalog: APB05422. | |
| Everolimus Impurity 23 (Everolimus-13C2-D4) | Everolimus Impurity 23 (Everolimus-13C2-D4). Uses: For analytical and research use. Group: Impurity standards. CAS No. 1661009-29-5. Molecular Formula: C5113C2H79D4NO14. Mole Weight: 964.25. Catalog: APB1661009295. | |
| Everolimus Impurity 24 (Everolimus-D4) | Everolimus Impurity 24 (Everolimus-D4). Uses: For analytical and research use. Group: Impurity standards. CAS No. 1338452-54-2. Molecular Formula: C53H79D4NO14. Mole Weight: 962.26. Catalog: APB1338452542. | |
| Everolimus Impurity 25 | Everolimus Impurity 25. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C53H83NO14. Mole Weight: 958.24. Catalog: APB07749. | |
| Everolimus Impurity 26 | Everolimus Impurity 26. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C32H49NO9. Mole Weight: 591.74. Catalog: APB07750. | |
| Everolimus Impurity 27 | Everolimus Impurity 27. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C54H85NO14. Mole Weight: 972.27. Catalog: APB07751. | |
| Everolimus Impurity 28 | Everolimus Impurity 28. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C54H85NO14. Mole Weight: 972.27. Catalog: APB07752. | |
| Everolimus Impurity 501-95 | Everolimus Impurity 501-95. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Everolimus Impurity 501-95. Molecular Formula: C53H83NO14. Mole Weight: 958.22. Catalog: APB05421. | |
| Everolimus Impurity 6 | Everolimus Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1704711-12-5. Molecular Formula: C54H85NO14. Mole Weight: 972.27. Catalog: APB1704711125. | |
| Everolimus Impurity 7 | Everolimus Impurity 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2402744-97-0. Molecular Formula: C53H83NO14. Mole Weight: 958.24. Catalog: APB2402744970. | |
| Everolimus Impurity 9-O-Hydroxyethyl sirolimus (009-96) | Everolimus Impurity 9-O-Hydroxyethyl sirolimus (009-96). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Everolimus Impurity 9-O-Hydroxyethyl sirolimus(009-96). Molecular Formula: C53H83NO14. Mole Weight: 958.22. Catalog: APB05424. | |
| Everolimus Impurity Everolimus-19-ene open ring (804-95) | Everolimus Impurity Everolimus-19-ene open ring (804-95). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-1-(2-((2R, 3R, 6S)-2-hydroxy-6-((2S, 3E, 5E, 7E, 9S, 11R, 13R, 14R, 15E, 17R, 19E, 21R)-14-hydroxy-22-((1S, 3R, 4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-2, 13-dimethoxy-3, 9, 11, 15, 17, 21-hexamethyl-12, 18-dioxodocosa-3, 5, 7, 15, 19-pentaen-1-yl)-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylic acid. Molecular Formula: C53H83NO14. Mole Weight: 958.22. Catalog: APB05423. | |
| Everolimus Isomer C | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: 9,14-Deepoxy-15-deoxo-14-deoxy-9,15-epoxy-15-hydroxy-42-O-(2-hydroxyethyl)-14-oxorapamycin. Grades: 80%. CAS No. 908340-97-6. Molecular formula: C53H83NO14. Mole weight: 958.25. | |
| Everolimus Isomer C | Everolimus Isomer C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 908340-97-6. Molecular Formula: C53H83NO14. Mole Weight: 958.24. Catalog: APB908340976. | |
| Everolimus O-Desmethyl Impurity (Mixture of Diastereomers) | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: 27-O-Desmethyl Everolimus. Grades: > 95%. Molecular formula: C52H81NO14. Mole weight: 944.22. | |
| Everolimus O-ethyl impurity | Everolimus O-ethyl impurity. CAS No. 1704711-12-5. Product ID: 8-05125. Molecular formula: C54H85NO14. Mole weight: 972.28. |  |
| Everolimus O-Ethyl Impurity | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: 7-O-Desmethyl-7-O-ethyl Everolimus. Grades: > 95%. CAS No. 1704711-12-5. Molecular formula: C54H85NO14. Mole weight: 972.28. | |
| Everolimus Open-Ring Acid Impurity | Everolimus Open-Ring Acid Impurity. Uses: For analytical and research use. Group: Impurity standards. CAS No. 769905-89-7. Molecular Formula: C53H85NO15. Mole Weight: 976.25. Catalog: APB769905897. | |
| Everolimus O-Silyl Impurity | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: 42-O-tert-Butyldimethylsilyloxyethyl Rapamycin; 42-O-[2-[[ (1, 1-Dimethylethyl) dimethylsilyl]oxy]ethyl]rapamycin. Grades: > 95%. CAS No. 159351-68-5. Molecular formula: C59H97NO14Si. Mole weight: 1072.52. | |
| Everolimus Related Compound 1 | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: O-Desmethyl Everolimus. Grades: > 95%. CAS No. 745779-75-3. Molecular formula: C52H81NO14. Mole weight: 944.22. | |
| Everolimus Related Compound 3 | Everolimus Ring-Opening Impurity. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: (2S)-1-[[(2R,3R,6S)-6-[(2S,3E,5E,7E,9S,11R)-2,13-Dimethoxy-3,9,11-trimethyl-12-oxo-3,5,7-tridecatrienyl]tetrahydro-2-hydroxy-3-methyl-2H-pyran-2-yl]oxoacetyl]-2-piperidinecarboxylic Acid. Grades: 65%. CAS No. 147438-30-0. Molecular formula: C32H49NO9. Mole weight: 591.75. | |
| Everolimus Related Compound 4 | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: (2S)-1-[2-[(2R, 3R, 6S)-6-[(2S, 3E, 5E, 7E, 9S, 11R, 13R, 14R, 15E, 17R, 20S, 21R)-14, 20-Dihydroxy-22-[(1S, 3R, 4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2, 13-dimethoxy-3, 9, 11, 15, 17, 21-hexamethyl-12, 18-dioxo-3, 5, 7, 15-docosatetraen-1-yl]tetrahydro-2-hydroxy-3-methyl-. Grades: > 95%. Molecular formula: C57H91NO16. Mole weight: 1046.36. | |
| Everolimus Related Compound 5 | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: Di-tert-butyl-4-methylene-2,5-cyclohexadienone; 2,6-Di-t-butyl-4-methylene-2,5-cyclohexadienone. Grades: > 95%. CAS No. 2607-52-5. Molecular formula: C15H22O. Mole weight: 218.34. | |
| Everolimus Related Compound 5 | Everolimus Related Compound 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2607-52-5. Molecular Formula: C15H22O. Mole Weight: 218.34. Catalog: APB2607525. | |
| Everolimus Ring-Opening Impurity | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: Everolimus Retroaldol Degradation Product. Grades: > 95%. CAS No. 1708118-13-1. Molecular formula: C53H83NO14. Mole weight: 958.25. | |
| Evexomostat | Evexomostat is a methionine aminopeptidase 2 (MetAP2) inhibitor. Synonyms: poly ({N-[ (2RS) -2-hydroxypropyl]methacrylamide}-co-[N-methacryloylgly-cyl-L-phenylalanyl-L-leucyl-N1- (trans-4-{[ ({ (3R, 4S, 5S, 6R) -5-methoxy-4-[ (2R, 3R) -2-methyl-3- (3-methylbut-2-en-1-yl) oxiran-2-yl]-1-oxaspiro[2. 5]-octan-6-yl}oxy) carbonyl]amino}cyclohexyl) glycinamide (~0.91:0.09 x)]); poly([N-(2-hydroxypropyl)methacrylamide]-co-{methacryloyl-Gly-Phe-Leu-Gly amide with O-[ (trans-4-aminocyclohexyl) carbamoyl]fumagillol}). CAS No. 2416263-67-5. Molecular formula: [(C7H13NO2)n(C46H68N6O10)]m. | |
| Evifacotrep | Evifacotrep is a short transient receptor potential channel 5 (TRPC5) antagonist. Synonyms: 4-chloro-5-{4-[4-fluoro-2-(trifluoromethyl)phenoxy]-5,8-dihydropyrido[3,4-d]pyrimidin-7(6H)-yl}pyridazin-3(2H)-one. CAS No. 2413739-88-3. Molecular formula: C18H12ClF4N5O2. Mole weight: 441.77. | |
| Evinacumab | Evinacumab (REGN1500) is a human anti- ANGPTL3 ( angiopoietin-like protein 3 ) monoclonal antibody (IgG4 class antibody). Evinacumab reduces plasma lipids in dyslipidemic mice by blocking ANGPTL3. Evinacumab can be used in studies of homozygous familial hypercholesterolaemia (HoFH), refractory hypercholesterolaemia (both familial and non-familial) and severe hypertriglyceridaemia [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN1500. CAS No. 1446419-85-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99194. | |
| Evinacumab | Evinacumab is a humanized anti-ANGPTL3 monoclonal antibody. Evinacumab has the potential therapeutic activity against homozygous familial hypercholesterolemia. Synonyms: Evkeeza; REGN1500. CAS No. 1446419-85-7. | |
| Evixapodlin | Evixapodlin is a human programmed cell death ligand 1 (PD-1/PD-L1) protein/protein interaction inhibitor with an IC50 of 0.213 nM. It has anticancer and antiviral functions. Synonyms: (12S,122S)-62,72-dichloro-53,86-dimethoxy-3,10-diaza-5,8(2,5)-dipyrazina-1,12(2)-dipyrrolidina-6,7(1,3)-dibenzenadodecaphane-15,125-dione; (5S, 5'S)-5, 5'- ( ( ( (5, 5'- (2, 2'-dichloro-[1, 1'-biphenyl]-3, 3'-diyl)bis (3-methoxypyrazine-5, 2-diyl))bis (methylene))bis (azanediyl))bis (methylene))bis (pyrrolidin-2-one); 2-Pyrrolidinone, 5, 5'-[ (2, 2'-dichloro[1, 1'-biphenyl]-3, 3'-diyl) bis[ (3-methoxy-5, 2-pyrazinediyl) methyleneiminomethylene]]bis-, (5S,5'S)-; PD-1/PD-L1-IN 7. Grades: ≥98%. CAS No. 2374856-75-2. Molecular formula: C34H36Cl2N8O4. Mole weight: 691.61. | |
| Evobrutinib | Evobrutinib (M2951) is an orally active, potent, highly selective and irreversibly covalent BTK inhibitor, with an IC 50 of 8.9 nM. Evobrutinib (M2951) can be used for the research of autoimmune diseases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: M2951; MSC2364447C. CAS No. 1415823-73-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101215. | |
| Evocalcet | Evocalcet (KHK7580) is an orally active calcium sensing receptor ( CaSR ) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KHK7580. CAS No. 870964-67-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17613. | |
| Evocalcet | Evocalcet is a calcium-sensing receptor agonist under the development of Kyowa Hakko Kirin. Phase III clinical trials for Secondary hyperparathyroidism are on-going in Japan. Uses: Secondary hyperparathyroidism. Synonyms: MT-4580; MT 4580; MT4580; KHK-7580; KHK7580; KHK 7580; Evocalcet;2-(4-((S)-3-(((R)-1-(naphthalen-1-yl)ethyl)amino)pyrrolidin-1-yl)phenyl)acetic acid. Grades: 98%. CAS No. 870964-67-3. Molecular formula: C24H26N2O2. Mole weight: 374.48. | |
| Evodenoson | Evodenoson is a selective agonist of the A 2A adenosine receptor. Evodenosons primary actions include reducing inflammatory responses, decreasing intestinal fluid secretion, edema, tissue damage, and neutrophil infiltration induced by Clostridium difficile toxin A. Evodenosons protective effect is achieved by reducing myeloperoxidase (MPO) and adenosine deaminase (ADA) activities, and by lowering the production of tumor necrosis factor-alpha (TNF-α) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ATL 313; DE 112. CAS No. 844873-47-8. Pack Sizes: 1 mg. Product ID: HY-105017. | |
| Evodenoson | Evodenoson is a selective A2A adenosine receptor agonist. Phase II clinical trials for the treatment of Glaucoma and Ocular hypertension were discontinued. Uses: Glaucoma;ocular hypertension. Synonyms: ATL313; ATL 313; ATL-313; DE-112; DE 112; DE112; methyl 4-[3-[6-amino-9-[(2R,3R,4S,5S)-5-(cyclopropylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]purin-2-yl]prop-2-ynyl]piperidine-1-carboxylate. Grades: 98%. CAS No. 844873-47-8. Molecular formula: C23H29N7O6. Mole weight: 499.53. | |
| Evodiamine | Evodiamine - Product ID: NST-10-12. Category: Alkaloids. Alternative Names: d-Evodiamine. Purity: 98%. Test method: HPLC. CAS No. 518-17-2. Pack Sizes: 25g, 50g, 125g, 250g. Appearance: White to pale yellow powder. Molecular formula: C19H17N3O. Mole weight: 303.36. Storage: +2 +8 °C. |  |
| Evodiamine | A chemical extracted from Evodia plants, and has been shown to reduce fat uptake. Group: Biochemicals. Alternative Names: (13bS)-8, 13, 13b-14-Tetrahydro-14-methyl-indolo[2', 3':3, 4]pyrido[2, 1-b]quinazolin-5(7H)-one; d-Evodiamine; (+)-Evodiamine. Grades: Highly Purified. CAS No. 518-17-2. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| Evodiamine | Evodiamine is an alkaloid isolated from the fruit of Evodia rutaecarpa Bentham with diverse biological activities including anti-inflammatory, anti-obesity, and antitumor. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Evodiamine; d-Evodiamine. CAS No. 518-17-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg. Product ID: HY-N0114. | |
| Evodiamine 98% HPLC | Evodiamine 98% HPLC. |  CA, FL & NJ |
| Evofosfamide | Evofosfamide (TH-302) is a hypoxia -activated proagent with IC 50 of 10 μM and 1000 μM in hypoxia (N 2 ) and normoxia (21% O 2 ), respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TH-302. CAS No. 918633-87-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10535. | |
| Evofosfamide | Evofosfamide is a hypoxia-activated prodrug consisting of a 2-nitroimidazole phosphoramidate conjugate with potential antineoplastic activity. The 2-nitroimidazole moiety of hypoxia-activated prodrug TH-302 acts as a hypoxic trigger, releasing the DNA-alkylating dibromo isophosphoramide mustard moiety within hypoxic regions of tumors. Normoxic tissues may be spared due to the hypoxia-specific activity of this agent, potentially reducing systemic toxicity. Synonyms: TH-302; TH 302; TH302; 2-bromo-N-[(2-bromoethylamino)-[(3-methyl-2-nitroimidazol-4-yl)methoxy]phosphoryl]ethanamine. Grades: > 98%. CAS No. 918633-87-1. Molecular formula: C9H16Br2N5O4P. Mole weight: 449.04. | |
| Evogliptin | This active molecular is a selective dipeptidyl peptidase 4 (DPP4) inhibitor under the development of Dong-A. Evogliptin improves insulin resistance and delays the onset of diabetes. Evogliptin monotherapy improved HbA1c, fasting plasma glucose level, OGTT results and β-cell function. In Sep 1st 2016, preclinical trials in Type-2 diabetes mellitus (Combination therapy) in Russia was on-going. In Sep 12th 2016, Phase-I clinical trials in non-alcoholic steatohepatitis (Combination therapy) in USA was on-going. Uses: Type-2 diabetes mellitus. Synonyms: (3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-[(2-methylpropan-2-yl)oxymethyl]piperazin-2-one;CHEMBL1779710; UNII-09118300L7; DA-1229; DA 1229; DA1229; 1222102-29-5; Evogliptin [INN];1246960-27-9 (HCl). Grades: 98%. CAS No. 1222102-29-5. Molecular formula: C19H26F3N3O3. Mole weight: 401.43. | |
| Evogliptin hydrochloride | Evogliptin is a DPP-4 inhibitor, for the treatment of type 2 diabetes mellitus in patients with inadequately controlled by diet and exercise alone, or in combination with metformin when diet and exercise plus metformin alone do not provide satisfactory glycaemic control. CAS No. 1246960-27-9. Molecular formula: C19H27ClF3N3O3. Mole weight: 401.42. | |
| Evogliptin tartrate | Evogliptin (DA-1229) tartrate is an orally active DPP4 inhibitor with significant and sustained hypoglycaemic effects in mouse models. Evogliptin tartrate also inhibits the production of inflammatory and fibrotic signals in hepatocytes by inducing autophagy. Evogliptin tartrate can be used in studies of type 2 diabetes, osteoporosis, renal impairment and chronic liver inflammation [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DA-1229 tartrate. CAS No. 1222102-51-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117985B. | |
| Evogliptin Tartrate | Evogliptin is an antidiabetic drug in the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Synonyms: 2-Piperazinone, 4-[(3R)?-3-amino-1-oxo-4-(2,?4,?5-trifluorophenyl)?butyl]?-3-[(1,?1-dimethylethoxy)?methyl]?-, (3R)?-, (2R,?3R)?-2,?3-dihydroxybutanedioat?e (1:1). Grades: > 95%. CAS No. 1222102-51-3. Molecular formula: C19H26F3N3O3. C4H6O6. Mole weight: 401.43 150.09. | |
| Evogliptin Tartrate Impurity S1 | An isomer of Evogliptin. Evogliptin is an antidiabetic drug in the dipeptidyl peptidase-4 (DPP-6) inhibitor class of drugs. Synonyms: 2-Piperazinone, 4-[(3S)?-3-amino-1-oxo-4-(2,?4,?5-trifluorophenyl)?butyl]?-3-[(1,?1-dimethylethoxy)?methyl]?-, (3R)?-, (2R,?3R)?-2,?3-dihydroxybutanedioat?e (1:1). Grades: > 95%. Molecular formula: C19H26F3N3O3. C4H6O6. Mole weight: 401.43 150.09. | |
| Evogliptin Tartrate Impurity S2 | An isomer of Evogliptin. Evogliptin is an antidiabetic drug in the dipeptidyl peptidase-4 (DPP-5) inhibitor class of drugs. Synonyms: 2-Piperazinone, 4-[(3S)?-3-amino-1-oxo-4-(2,?4,?5-trifluorophenyl)?butyl]?-3-[(1,?1-dimethylethoxy)?methyl]?-, (3S)?-, (2R,?3R)?-2,?3-dihydroxybutanedioat?e (1:1). Grades: > 95%. Molecular formula: C19H26F3N3O3. C4H6O6. Mole weight: 401.43 150.09. | |
| Evogliptin Tartrate Impurity S3 | An isomer of Evogliptin. Evogliptin is an antidiabetic drug in the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Synonyms: 2-Piperazinone, 4-[(3R)?-3-amino-1-oxo-4-(2,?4,?5-trifluorophenyl)?butyl]?-3-[(1,?1-dimethylethoxy)?methyl]?-, (3S)?-, (2R,?3R)?-2,?3-dihydroxybutanedioat?e (1:1). Grades: > 95%. Molecular formula: C19H26F3N3O3. C4H6O6. Mole weight: 401.43 150.09. | |
| Evolitrine | Evolitrine is an alkaloid isolated from Fructus Evodiae. Synonyms: Evolitrin; 4,7-dimethoxyfuro[2,3-b]quinoline. Grades: 98%. CAS No. 523-66-0. Molecular formula: C13H11NO3. Mole weight: 229.23. | |
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