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| Product | Description | |
|---|---|---|
| Ex 26 | Ex 26 is a potent and selective S1P1 receptor antagonist (IC50 = 0.93 nM) with > 3,000-fold selectivity over S1P2, S1P3, S1P4 and S1P5. It causes lymphocyte sequestration in peripheral lymph nodes, and upregulates S1P1 receptor expression. Synonyms: 1-[[[5'-[[1-(4-Chloro-3-methylphenyl)ethyl]amino]-2'-fluoro-3,5-dimethyl[1,1'-biphenyl]-4-yl]carbonyl]amino]-cyclopropanecarboxylic acid. Grade: ≥98% by HPLC. CAS No. 1233332-37-0. Molecular formula: C28H28ClFN2O3. Mole weight: 494.98. |  |
| EX 527 | EX 527. Group: Biochemicals. Grades: Purified. CAS No. 49843-98-3. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| EX-527 | EX 527 is a potent and selective SIRT1 inhibitor with IC50 of 38 nM, exhibits >200-fold selectivity against SIRT2 and SIRT3. Synonyms: SEN0014196; EX-527; EX-527; EX-527; Selisistat. Grade: >98%. CAS No. 49843-98-3. Molecular formula: C13H13ClN2O. Mole weight: 248.71. | |
| EX-527 | EX-527 Inhibitor. Uses: Scientific use. Product Category: T6111. CAS No. 49843-98-3. |  |
| EX-527 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| EX-527 R-enantiomer | EX-527 R-enantiomer is the R-enantiomer of EX-527, which is a potent and selective SIRT1 inhibitor and with no inhibition on SIRT3 and SIRT3. It is a negative control of the active form EX-527 S-enantiomer. Synonyms: Selisistat R-enantiomer; (R)-Selisistat; EX-527(R); EX 527(R); EX527(R). Grade: >98%. CAS No. 848193-69-1. Molecular formula: C13H13ClN2O. Mole weight: 248.71. | |
| EX 527 (Selisistat, EX527, SIRT1 Inhibitor III) | EX 527 (Selisistat, EX527, SIRT1 Inhibitor III). Group: Biochemicals. Alternative Names: 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide. Grades: Highly Purified. CAS No. 49843-98-3. Pack Sizes: 10mg. Molecular Formula: C13 H13 ClN 2, Molecular Weight: 248.7. US Biological Life Sciences. | Worldwide |
| EX-527 S-enantiomer | EX-527 S-enantiomer is the S-enantiomer of EX-527, which is a potent and selective SIRT1 inhibitor and with no inhibition on SIRT3 and SIRT3. Synonyms: Selisistat S-enantiomer; EX-527(S); (S)-Selisistat; EX 527(S); EX527(S); EX-527S; EX527S. Grade: >98%. CAS No. 848193-68-0. Molecular formula: C13H13ClN2O. Mole weight: 248.71. | |
| EX-527, SIRT1 Inhibitor (6-Chloro-2,3,4,9-tetrahydro-1Hcarbazole- 1-carboxamide (racemic)) | Selective SIRT1 inhibitor (IC50=98nM). Does not inhibit other HDACs or SIRT family members. Group: Biochemicals. Alternative Names: 6-Chloro-2,3,4,9-tetrahydro-1Hcarbazole- 1-carboxamide (racemic). Grades: Highly Purified. CAS No. 49843-98-3. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| Exalamide | Exalamide (2-(Hexyloxy)benzamide), an arenecarboxamide, is a potent antifungal agent. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-(hexyloxy)-benzamid;2-n-hexyloxybenzamide;h.p.216;o-hexyloxy-benzamid;2-(HEXYLOXY)BENZAMIDE;HBA;HYPERAN;EXALAMIDE. Product Category: Inhibitors. Appearance: White Solid. CAS No. 53370-90-4. Molecular formula: C13H19NO2. Mole weight: 221.3. Purity: 0.9993. Canonical SMILES: O=C(N)C1=CC=CC=C1OCCCCCC. Density: 1.03 g/cm³. Product ID: ACM53370904. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Exalamide | Exalamide is a derivative of salicylamide used as an antifungal. Uses: Used as an antifungal. Synonyms: 2-(Hexyloxy)benzamide; 2-hexoxybenzamide. Grade: ≥95%. CAS No. 53370-90-4. Molecular formula: C13H19NO2. Mole weight: 221.3. | |
| Exalamide | Exalamide. Group: Biochemicals. Alternative Names: HBA, hyperan, 2-(hexyloxy)benzamide. Grades: Highly Purified. CAS No. 53370-90-4. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C13H19NO2. US Biological Life Sciences. | Worldwide |
| Exaltenone | Exaltenone. CAS No. 14595-54-1. VIGON Item # 502773. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers, (Z)-musk pentane. |  America & Internationally |
| Exaltolide® | Exaltolide®. CAS No. 106-02-5. FEMA No. 2840. Kosher: Y. VIGON Item # 502774. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers, omega-pentadecalactone. | America & Internationally |
| Exaltolide® Total | Exaltolide® Total. CAS No. 106-02-5. FEMA No. 2840. Kosher: Y. VIGON Item # 502775. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers. | America & Internationally |
| Exaluren disulfate | Exaluren (ELX-02) disulfate is an investigational, advanced synthetic eukaryotic ribosome selective glycoside (ERSG). Exaluren disulfate is being developed as a therapy for genetic diseases caused by nonsense mutations[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ELX-02 disulfate; NB-124 disulfate. CAS No. 2244622-33-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-114231B. |  |
| Exarafenib | Exarafenib (RAF/KIN_2787) is an orally-available, selective pan-RAF inhibitor. Exarafenib is effective in RAF-dependent cancers, including all classes of BRAF alterations. Exarafenib suppresses MAPK signaling in RAF-dependent melanoma cell lines. Exarafenib has anticancer activity[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RAF/KIN_2787. CAS No. 2639957-39-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147268. | |
| Exatecan | Exatecan is an inhibitor of DNA topoisomerase I, with an IC50 of 2.2 μM (0.975 μg/mL). It can be used to study cancer. Uses: Topoisomerase i inhibitors. Synonyms: DX-8951; (1S,9S)-1-Amino-9-ethyl-5-fluoro-1,2,3,9,12,15-hexahydro-9-hydroxy-4-methyl-10H,13H-benzo(de)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-10,13-dione; 10H,13H-Benzo(de)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-10,13-dione, 1-amino-9-ethyl-5-fluoro-1,2,3,9,12,15-hexahydro-9-hydroxy-4-methyl-, (1S-trans)-; NSC-829066. Grade: ≥95%. CAS No. 171335-80-1. Molecular formula: C24H22FN3O4. Mole weight: 435.45. | |
| Exatecan | Exatecan (DX-8951) is a DNA topoisomerase I inhibitor, with an IC 50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DX-8951. CAS No. 171335-80-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13631. | |
| Exatecan | Exatecan (DX-8951) is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 10H,13H-BENZO[DE]PYRANO[3,4:6,7]INDOLIZINO[1,2-B]QUINOLINE-10,13-DIONE, 1-AMINO-9-ETHYL-5-FLUORO-1,2,3,9,12,15-HEXAHYDRO-9-HYDROXY-4-METHYL-, (1S,9S)-, MONOMETHANESULFONATE (SALT);exatecan alideximer;(1S,9S)-1-Amino-9-ethyl-5-fluoro-1,2,3,9,12,15-hexahydro-9-hydroxy-4-methyl-10H,13H-benzo(de)pyrano(3,4:6,7)indolizino(1,2-b)quinoline-10,13-dione;Exatecan;DX 8951. Product Category: Inhibitors. CAS No. 171335-80-1. Molecular formula: C24H22FN3O4. Mole weight: 435.45. Purity: 0.994. Product ID: ACM171335801. Alfa Chemistry ISO 9001:2015 Certified. | |
| Exatecan | Exatecan has been used in trials studying the treatment of Sarcoma, Leukemia, Lymphoma, Lung Cancer, and Liver Cancer, among others. Alternative Names: Exatecan [INN]. DX-8951. DX-8951f. CAS No. 171335-80-1. Product ID: API171335801. Molecular formula: C24H22FN3O4. Mole weight: 435.4. SMILES: CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C5[C@H](CCC6=C5C(=CC(=C6C)F)N=C4C3=C2)N)O. Appearance: Solid Powder. Category: Anti-Tumor APIs. |  |
| Exatecan-d5 mesylate | Exatecan-d5 (DX8951f-d5) mesylate is deuterium labeled Exatecan mesylate (HY-13631A). Exatecan mesylate is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 ?M (0.975 ?g/mL). Exatecan mesylate can be used in cancer research[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: DX8951f-d5; Deuterated labeled Exatecan mesylate. CAS No. 2819276-88-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13631AS. | |
| Exatecan free base | Exatecan, also known as DX 8951, is a semisynthetic, water-soluble derivative of camptothecin with antineoplastic activity. Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death. This agent does not require enzymatic activation and exhibits greater potency than camptothecin and other camptothecin analogues. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DX 8951; DX 8951; DX 8951; Exatecan free base. Product Category: Others. Appearance: Solid powder. CAS No. 171335-80-1. Molecular formula: C24H22FN3O4. Mole weight: 435.46. Purity: >98%. IUPACName: (1S,9S)-1-Amino-9-ethyl-5-fluoro-1,2,3,9,12,15-hexahydro-9-hydroxy-4-methyl-10H,13H-benzo(de)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-10,13-dione. Canonical SMILES: O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=C5C6=C(CC[C@@H]5N)C(C)=C(F)C=C6N=C4C3=C2)=O. Product ID: ACM171335801-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| Exatecan mesilate hydrate | Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death. Synonyms: Exatecan methanesulfonate dihydrate; DX 8951 mesilate hydrate. CAS No. 197720-53-9. Molecular formula: C25H30FN3O9S. Mole weight: 567.58. | |
| Exatecan mesylate | Exatecan mesylate (DX8951f) is a DNA topoisomerase I inhibitor, with an IC 50 of 2.2 μM (0.975 μg/mL). Exatecan mesylate can be used in cancer research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DX8951f. CAS No. 169869-90-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-13631A. | |
| Exatecan mesylate | Exatecan Mesylate is a water soluble topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research. CAS No. 169869-90-3. Product ID: API169869903. Mole weight: 531.553. SMILES: CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C5[C@H](CCC6=C5C(=CC(=C6C)F)N=C4C3=C2)N)O.CS(=O)(=O)O. Category: Active Pharmaceutical Ingredients. | |
| Exatecan Mesylate | Exatecan mesylate is a semisynthetic, water-soluble derivative of camptothecin with antineoplastic activity. Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting the religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death. This agent does not require enzymatic activation and exhibits greater potency than camptothecin and other camptothecin analogs. Synonyms: DX 8951 mesylate; (1S,9S)-1-Amino-9-ethyl-5-fluoro-1,2,3,9,12,15-hexahydro-9-hydroxy-4-methyl-10H,13H-benzo(de)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-10,13-dione mesylate; 10H,13H-Benzo(de)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-10,13-dione, 1-amino-9-ethyl-5-fluoro-1,2,3,9,12,15-hexahydro-9-hydroxy-4-methyl-, (1S-trans)-, mesylate (1:1); NSC-829066 mesylate. Grade: >98%. CAS No. 169869-90-3. Molecular formula: C25H26FN3O7S. Mole weight: 531.56. | |
| Exatecan (mesylate) (GMP) | Exatecan mesylate (DX8951f ) GMP is a GMP-class Exatecan (HY-13631). Exatecan is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 ?M (0.975 ?g/mL), and can be used in cancer research[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DX8951f (GMP). CAS No. 169869-90-3. Pack Sizes: 10 mg; 50 mg; 100 mg. Product ID: HY-13631AG. | |
| Exatecan (Standard) | Exatecan (Standard) is the analytical standard of Exatecan. This product is intended for research and analytical applications. Exatecan (DX-8951) is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 ?M (0.975 ?g/mL), and can be used in cancer research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DX-8951 (Standard). CAS No. 171335-80-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13631R. | |
| Exbivirumab | Exbivirumab is a human monoclonal antibody that targets hepatitis B surface antigen. Exbivirumab has the potential for the treatment of hepatitis B infections. Grade: 95%. CAS No. 569658-80-6. Molecular formula: C15H11BrClNO2S. Mole weight: 384.7. | |
| Excess aluminum Ti3AlC2 MXene | Excessive aluminum Ti3AlC2 and rich aluminum lead to improved structural order and morphology of Ti3AlC2 grains, while also reducing oxygen activity, producing the highest stoichiometric MAX phase without affecting the quality of the obtained MXene. Uses: Hot press, mxene precursor. Group: Mxenes materials. |  |
| Exchange Reaction Buffer 10X | Exchange reaction buffer (10X) for P4410. Group: Molecular Biology. Alternative Names: For use with T4 polynucleotide kinase. Pack Sizes: 200ul, 1x1ml. US Biological Life Sciences. | Worldwide |
| Excisanin A | Excisanin A is a natural diterpenoid compound found in several plants. Synonyms: 1alpha,7alpha,12alpha,14beta-Tetrahydroxy-ent-kaur-16-en-15-one. Grade: >95%. CAS No. 78536-37-5. Molecular formula: C20H30O5. Mole weight: 350.45. | |
| Excisanin B | Excisanin B is extracted from the herbs of Isodon japonicus. It inhibits production of nitric oxide in LPS-induced murine macrophage RAW264.7 cells. Synonyms: 1alpha,7alpha,14beta-Trihydroxy-12alpha-acetoxykaura-16-ene-15-one. Grade: 98.0%. CAS No. 78536-36-4. Molecular formula: C22H32O6. Mole weight: 392.49. | |
| Exemestane | Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC 50 s of 30 nM and 40 nM for human placenta l and rat ovarian aromatase , respectively. Exemestane can be used for hormone-dependent breast cancer research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FCE 24304; EXE. CAS No. 107868-30-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13632. | |
| Exemestane-19-d3 (6-Methyleneandrosta-1,4-diene-3,17-dione-19-d3, FCE 24304-19-d3, Aromasin-19-d3) | An antineoplastic (hormonal). Group: Biochemicals. Alternative Names: 6-Methyleneandrosta-1,4-diene-3,17-dione-19-d3;FCE 24304-19-d3; Aromasin-19-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Exemestane (6-Methyleneandrosta-1,4-diene-3,17-dione, FCE-24304, Aromasin) | An antineoplastic (hormonal). Group: Biochemicals. Alternative Names: 6-Methyleneandrosta-1,4-diene-3,17-dione, FCE-24304, Aromasin. Grades: Highly Purified. CAS No. 107868-30-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Exemestane-[d2] | Exemestane-[d2] is a deuterium labelled analogue of Exemestane. Exemestane is a medication used for the treatment of certain types of breast cancer. It acts via inhibiting estrogen essential for some breast cancers' growth. Synonyms: 6-Methyleneandrosta-1,4-diene-3,17-dione-16,16-D2; Exemestane D2; (8R,9S,10R,13S,14S)-10,13-dimethyl-6-methylene-7,8,9,10,11,12,13,14,15,16-decahydro-3H-cyclopenta[a]phenanthrene-3,17(6H)-dione-16,16-d2; Aromasin-d2; Aromasine-d2; Exemestano-d2. Grade: 99.6% by HPLC; 99% atom D. Molecular formula: C20H22D2O2. Mole weight: 298.38. | |
| Exemestane-d3 | One of the isotopic labelled form of Exemestane, which is a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6-Methyleneandrosta-1,4-diene-3,17-dione-d3. Molecular formula: C20H21O2D3. Mole weight: 299.43. | |
| Exemestane-d5 | One of the isotopic labelled form of Exemestane, which is a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6-Methyleneandrosta-1,4-diene-3,17-dione-d5. Molecular formula: C20H19O2D5. Mole weight: 301.44. | |
| Exemestane EP Impurity H | Exemestane EP Impurity H. Uses: For analytical and research use. Group: Impurity standards. CAS No. 122370-91-6. Molecular formula: C20H26O2. Mole weight: 298.43. Catalog: APB122370916. | |
| Exemestane Impurity 1 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 1,2-α-Epoxy Exemestane; (1α,2α)-1,2-Epoxy-6-methyleneandrost-4-ene-3,17-dione. Grade: > 95%. CAS No. 159354-61-7. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Exemestane Impurity 11 | Exemestane Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 107868-36-0. Molecular formula: C20H23ClO2. Mole weight: 330.85. Catalog: APB107868360. | |
| Exemestane Impurity 13 | Exemestane Impurity 13. Uses: For analytical and research use. Group: Impurity standards. CAS No. 152764-29-9. Molecular formula: C20H26O3. Mole weight: 314.43. Catalog: APB152764299. | |
| Exemestane Impurity 3 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6,16-Dimethylideneandrosta-1,4-diene-3,17-dione. Grade: > 95%. Molecular formula: C21H24O2. Mole weight: 308.42. | |
| Exemestane Impurity 3 | Exemestane Impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1012054-48-6. Molecular formula: C20H28O3. Mole weight: 316.44. Catalog: APB1012054486. | |
| Exemestane Impurity 4 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 16-methylideneandrosta-1,4-diene-3,17-dione. Grade: > 95%. Molecular formula: C20H24O2. Mole weight: 296.41. | |
| Exemestane Impurity 6 | Exemestane Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1331732-05-8. Molecular formula: C20H26O3. Mole weight: 314.43. Catalog: APB1331732058. | |
| Exemestane Impurity 8 (Testosterone Impurity 6) | Exemestane Impurity 8 (Testosterone Impurity 6). Uses: For analytical and research use. Group: Impurity standards. CAS No. 1035-69-4. Molecular formula: C19H24O2. Mole weight: 284.4. Catalog: APB1035694. | |
| Exemestane Impurity E | Exemestane Impurity E. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2'R,8R,9S,10R,13S,14S)-10,13-dimethyl-7,8,9,11,12,13,15,16-octahydrospiro[cyclopenta[a]phenanthrene-6,2'-oxirane]-3,17(10H,14H)-dione. CAS No. 152764-24-4. Molecular formula: C20H24O3. Mole weight: 312.4. Catalog: APB152764244. | |
| Exemestane Impurity G | Exemestane Impurity G. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2'S,8R,9S,10R,13S,14S)-10,13-dimethyl-7,8,9,11,12,13,15,16-octahydrospiro[cyclopenta[a]phenanthrene-6,2'-oxirane]-3,17(10H,14H)-dione. CAS No. 152764-31-3. Molecular formula: C20H24O3. Mole weight: 312.4. Catalog: APB152764313. | |
| Exemestane Metabolite 1 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 17β-Hydroxy Exemestane Sulfamate; (17β)-17-[(Aminosulfonyl)oxy]-6-methyleneandrosta-1,4-dien-3-one. Grade: > 95%. Molecular formula: C20H27NO4S. Mole weight: 377.51. | |
| Exemestane Metabolite 2 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6-Hydroxy-6-(methoxymethyl)-androsta-1,4-diene-3,17-dione. Grade: > 95%. Molecular formula: C21H28O4. Mole weight: 344.45. | |
| Exemestane Related Compound | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6α-(Methoxymethyl)androsta-1,4-dien-3,17-dione. Grade: > 95%. CAS No. 881896-95-3. Molecular formula: C21H28O3. Mole weight: 328.46. | |
| Exemestane Related Compound 1 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6β-(Formyl)androsta-1,4-dien-3,17-dione. Grade: > 95%. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Exemestane Related Compound 2 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 17-hydroxy-8,10,13-trimethyl-3-oxo--decahydro-3H-cyclopenta[a]phenanthrene-6-carboxylic acid. Grade: > 95%. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Exemestane Related Compound 2 (17-alpha isomer) | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 17-alpha-hydroxy-8,10,13-trimethyl-3-oxo--decahydro-3H-cyclopenta[a]phenanthrene-6-carboxylic acid. Grade: > 95%. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Exemestane Related Compound 2 (17-beta isomer) | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 17-beta-hydroxy-8,10,13-trimethyl-3-oxo--decahydro-3H-cyclopenta[a]phenanthrene-6-carboxylic acid. Grade: > 95%. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Exemestane Related Compound A | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 1,2-Dihydro Exemestane; 6-Methyleneandrost-4-ene-3,17-dione; 6-Methyleneandrost-4-en-3,17-dione. Grade: > 95%. CAS No. 19457-55-7. Molecular formula: C20H26O2. Mole weight: 298.43. | |
| Exemestane Related Compound A | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Exemestane Related Compound B | Isotope labelled Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: Androsta-1,4-diene-3,17-dione, 6-(hydroxymethyl). Grade: > 95%. CAS No. 184972-09-6. Molecular formula: C20H26O3. Mole weight: 314.43. | |
| Exemestane Related Compound B | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Exemestane (Standard) | Exemestane (Standard) is the analytical standard of Exemestane. This product is intended for research and analytical applications. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC 50 s of 30 nM and 40 nM for human placenta l and rat ovarian aromatase , respectively. Exemestane can be used for hormone-dependent breast cancer research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FCE 24304(Standard); EXE (Standard). CAS No. 107868-30-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-13632R. | |
| Exemestane System Suitability Mixture | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Exenatide | Exenatide, naturally occured in the saliva of the Gila monster, an incretin mimetic that has glucoregulatory effect. As a glucagon-like peptide-1 (GLP-1) receptor agonist, it stimulates proliferation of HCAECs through PKA-PI3K/Akt-eNOS activation pathways. Uses: Hypoglycemic agents. Synonyms: L-Serinamide, L-histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-tryptophyl-L-leucyl-L-lysyl-L-asparaginylglycylglycyl-L-prolyl-L-seryl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-; L-. CAS No. 141758-74-9. Molecular formula: C184H282N50O60S. Mole weight: 4186.56. | |
| Exenatide acetate | Exenatide acetate is a potent peptide agonist of the glucagon-like peptide 1 (GLP-1) receptor with Ki value of 136 pM. It is a 39 amino acid peptide, which increases intracellular cAMP in pancreatic acinar cells and has no effect on VIP receptors. It was first isolated from the venom of H. horridum and consequently synthesized. It stimulates proliferation of HCAECs through PKA-PI3K/Akt-eNOS activation pathways via a GLP-1 receptor-dependent mechanism. It also stimulates glucose-induced insulin secretion in isolated rat islets and proinsulin expression in mouse insulinoma βTC-1 cells. It protects hippocampal neurons against glutamate-induced apoptosis, suggesting utility in neurodegenerative diseases. It also has anxiolytic and anti-depressant effects and induces satiety. It is an incretin mimetic approved for type 2 diabetes mellitus treatment. It also has neurotrophic/protective activity in cellular and animal models of stroke, Alzheimer's and Parkinson's diseases. Synonyms: L-Serinamide, L-histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-tryptophyl-L-leucyl-L-lysyl-L-asparaginylglycylglycyl-L-prolyl-L-seryl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-, ac. Grade: >9 | |
| Exenatide acetate | Exenatide acetate. Group: Biochemicals. Alternative Names: Exendin-4. Grades: Highly Purified. CAS No. 141732-76-5. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C184H282N50O60S·C2H4O2 . US Biological Life Sciences. | Worldwide |
| Exendin-3 | Exendin-3 is a biologically active peptides isolated from venoms of the Gila monster lizards, Heloderma horridurn. Uses: Scientific research. Group: Peptides. CAS No. 130357-25-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1543. | |
| Exendin-3 | Exendin-3 is a bioactive peptide isolated from venoms of the Gila monster lizards, Heloderma horridurn. Synonyms: H-His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2; L-histidyl-L-seryl-L-alpha-aspartyl-glycyl-L-allothreonyl-L-phenylalanyl-L-allothreonyl-L-seryl-L-alpha-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isoleucyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-lysyl-L-asparagyl-glycyl-glycyl-L-prolyl-L-seryl-L-seryl-glycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-L-serinamide. Grade: ≥95%. CAS No. 130357-25-4. Molecular formula: C184H282N50O61S. Mole weight: 4202.57. | |
| Exendin 3 (9-39) | Exendin (9-39) is a specific and competitive glucagon-like peptide-1receptor antagonist (Kd = 1.7 nM at cloned human GLP-1 receptors). Exendin (9-39) inhibits insulin release and cAMP production caused by GLP-1 (7-36), exendin-3, and exendin-4. Synonyms: Exendin 9-39; Exendin 9 39; H-DL-Asp-DL-Leu-DL-Ser-DL-Lys-DL-Gln-DL-Met-DL-Glu-DL-Glu-DL-Glu-DL-Ala-DL-Val-DL-Arg-DL-Leu-DL-Phe-DL-xiIle-DL-Glu-DL-Trp-DL-Leu-DL-Lys-DL-Asn-Gly-Gly-DL-Pro-DL-Ser-DL-Ser-Gly-DL-Ala-DL-Pro-DL-Pro-DL-Pro-DL-Ser-NH2; DL-alpha-aspartyl-DL-leucyl-DL-seryl-DL-lysyl-DL-glutaminyl-DL-methionyl-DL-alpha-glutamyl-DL-alpha-glutamyl-DL-alpha-glutamyl-DL-alanyl-DL-valyl-DL-arginyl-DL-leucyl-DL-phenylalanyl-DL-isoleucyl-DL-alpha-glutamyl-DL-tryptophyl-DL-leucyl-DL-lysyl-DL-asparagyl-glycyl-glycyl-DL-prolyl-DL-seryl-DL-seryl-glycyl-DL-alanyl-DL-prolyl-DL-prolyl-DL-prolyl-DL-serinamide. Grade: ≥95%. CAS No. 133514-43-9. Molecular formula: C149H234N40O47S. Mole weight: 3369.76. | |
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