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| Product | Description | |
|---|---|---|
| Evatanepag | Evatanepag (CP-533536) is a non-prostanoid, potent and selective EP 2 receptor agonist. Evatanepag can induce local bone formation in vivo. Evatanepag can be used in the research of fractures, bone defects, asthma [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-533536 free acid. CAS No. 223488-57-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14839. |  |
| Evenamide | Evenamide (NW-3509) is an orally available voltage-gated sodium channel (VGSC) blocker ( K i =0.4 μM) for the research of schizophrenia. Evenamide shows efficacy in a broad spectrum of rodent models of psychosis, mania, depression, and aggressiveness [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NW-3509. CAS No. 1092977-61-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17612. | |
| Evenamide | Evenamide is a selective voltage-gated sodium and?/or calcium channel modulator, including subtypes Nav1.3, Nav1.7, and Nav1.8. It may be potentia useful in preventing, alleviating and curing a wide range of pathologies, including neurol., cognitive, psychiatric, inflammatory, urogenital and gastrointestinal diseases. It has shown efficacy in animal models of psychosis, mania, depression, and aggression. It was under development by Newron Pharmaceuticals as an add-on therapy for the treatment of schizophrenia. It is in phase II clinical trials. Uses: Evenamide may be potentia useful in preventing, alleviating and curing a wide range of pathologies, including neurol., cognitive, psychiatric, inflammatory, urogenital and gastrointestinal diseases. it is used as an add-on therapy for the treatment of schizophrenia. Synonyms: 2-[2-(3-Butoxyphenyl)ethylamino]-N,N-dimethylacetamide; NW-3509; NW 3509; NW3509; NW-3509A; Evenamide. Grade: >98%. CAS No. 1092977-61-1. Molecular formula: C16H26N2O2. Mole weight: 278.40. |  |
| Evening primrose oil | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. |  |
| Evening primrose oil microencapsulated powder | Evening primrose oil microencapsulated powder. Product ID: CDF4-0206. Molecular formula: NA. Category: Nutrient supplements. Product Keywords: Food Ingredients; Nutrients; CDF4-0206; Evening primrose oil microencapsulated powder; Nutrient supplements. Appearance: White to light yellow powder. Color: White to light yellow. Physical State: powder. Source and Preparation: evening primrose. Applications: Dietary supplements, nutritional supplements, cosmetic raw materials, etc. |  |
| Evernic Acid | Evernic acid is a secondary metabolite produced by some species of lichen. It is an inhibitor of two key plasmodial FAS-II enzymes PfFabZ and PfFabI (IC50 = 10.7 and 36.1 μM, respectively). Synonyms: NSC 81164; 2-hydroxy-4-(2-hydroxy-4-methoxy-6-methylbenzoyl)oxy-6-methylbenzoic acid. Grade: ≥98%. CAS No. 537-09-7. Molecular formula: C17H16O7. Mole weight: 332.3. | |
| Evernimicin | Evernimicin is an antibiotic that belongs to the orthosomycin class of antimicrobial agents. It was initially derived from the fermentation products of the soil bacterium Micromonospora carbonacea. Evernimicin is effective against a broad range of Gram-positive bacteria, including multidrug-resistant strains. It has shown activity against pathogens such as methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE), and Streptococcus pneumoniae. Synonyms: Ziracin; SCH 27899; SCH27899; SCH-27899; Flambamycin, 56-deacetyl-57-demethyl-45-O-de(2-methyl-1-oxopropyl)-12-O-(2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitro-α-L-arabino-hexopyranosyl)-, 56-(2,4-dihydroxy-6-methylbenzoate); O-(1R)-4-O-(2,4-Dihydroxy-6-methylbenzoyl)-2,3-O-methylene-D-xylopyranosylidene-(1→3-4)-α-L-lyxopyranosyl O-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitro-α-L-arabino-hexopyranosyl-(1→3)-O-2,6-dideoxy-4-O-(3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoyl)-β-D-arabino-hexopyranosyl-(1→4)-O-(1R)-2,6-dideoxy-D-arabino-hexopyranosylidene-(1→3-4)-O-6-deoxy-3-C-methyl-β-D-mannopyranosyl-(1→3)-O-6-deoxy-4-O-methyl-β-D-galactopyranosyl-(1→4)-2,6-di-O-methyl-β-D-mannopyranoside; Antibiotic 13-384-1; Everninomicin; Everninomicin 13384-1; Everninomycin; Sch 27899. Grade: 95%. CAS No. 109545-84-8. Molecular formula: C70H97Cl2NO38. Mole weight: 1631.41. | |
| Evernin | Evernin. Synonyms: 2-Hydroxy-4-[(2-hydroxy-4-methoxy-6-methylbenzoyl)oxy]-3,6-dimethylbenzoic acid methyl ester; Benzoic acid, 2-hydroxy-4-[(2-hydroxy-4-methoxy-6-methylbenzoyl)oxy]-3,6-dimethyl-, methyl ester. CAS No. 61631-65-0. Molecular formula: C19H20O7. Mole weight: 360.36. | |
| Everninomicin B | Everninomicin B is a carbohydrate antibiotic produced by Micromonospora carbonacea var. carbonacea. It has anti-gram-positive bacteria and mycobacterial activity. Synonyms: Everninomycin-B; R-451-B. CAS No. 53296-30-3. Molecular formula: C66H99Cl2NO36. Mole weight: 1553.38. | |
| Everninomicin C | Everninomicin C is a carbohydrate antibiotic produced by Micromonospora carbonacea var. CAS No. 53296-29-0. Molecular formula: C63H93Cl2NO34. Mole weight: 1479.30. | |
| Everninomicin D | Everninomicin D is a carbohydrate antibiotic produced by Micromonospora carbonacea var. carbonacea. It has anti-gram-positive bacteria and mycobacterial activity. Synonyms: Flambamycin, 57-demethyl-45-O-de(2-methyl-1-oxopropyl)-59-deoxo-23-deoxy-59-methoxy-45-O-methyl-12-O-(2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitro-alpha-L-arabino-hexopyranosyl)-, (59S)-. CAS No. 39340-46-0. Molecular formula: C66H99Cl2NO35. Mole weight: 1537.38. | |
| Evernyl | Evernyl (Methyl Atrarate). CAS No. 4707-47-5. VIGON Item # 500886. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers. |  America & Internationally |
| Everolimus | Everolimus is an inhibitor of mammalian target of rapamycin (mTOR) with an immunosuppressive activity which is comparable to that of rapamycin. It inhibits cytokine-mediated lymphocyte proliferation. Everolimus can be used as an immunosuppressant in the treatment of renal cell cancer and other cancers. Uses: Immunosuppressant. Synonyms: RAD-001; RAD001; RAD 001; Afinitor; Certican; Zortress; RAD001; SDZ-RAD. Grade: >98%. CAS No. 159351-69-6. Molecular formula: C53H83NO14. Mole weight: 958.24. | |
| Everolimus | Everolimus (RAD001) is a Rapamycin (HY-10219) derivative and a potent, selective and orally active mTOR1 inhibitor. Everolimus binds to FKBP-12 to generate an immunosuppressive complex. Everolimus inhibits tumor cells proliferation and induces cell apoptosis and autophagy. Everolimus has potent immunosuppressive and anticancer activities [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RAD001; SDZ-RAD. CAS No. 159351-69-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10218. | |
| Everolimus | Everolimus is an immunosuppressant analog of rapamycin (sirolimus) and inhibits growth factor-mediated proliferation of hematopoietic and nonhematopoietic cells. Everolimus shows a potent inhibitory effect on posttransplant lymphoproliferative disorder (PTLD)-derived cells in vitro and in vivo, in a dose range that can prevent allograft rejection, and may demonstrate activity in both the prevention and treatment of PTLDs in transplant patients. Group: Biochemicals. Alternative Names: Afinitor, Certican, RAD-001, Zortress; 40-O- (2-Hydroxyethyl) rapamycin; 42-O-(2-Hydroxy)ethyl Rapamycin; RAD; RAD 001; SDZ-RAD; XIENCE V. Grades: Highly Purified. CAS No. 159351-69-6. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. |  Worldwide |
| Everolimus | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopyenzyme activators, inhibitors & substrateseuropean pharmacopoeia (ph. eur.)pharmacopoeial standards. Alternative Names: Certican,Rapamycin, 42-O-(2-hydroxyethyl)-, 42-O-(2-Hydroxyethyl)rapamycin, RAD 001, Afinitor Disperz, SDZ-RAD, Afinitor, Zortress, Everolimus, Xience, XIENCE V, RAD, 40-O-(2-Hydroxyethyl)rapamycin, 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine, rapamycin deriv. | |
| Everolimus 27-O-Desmethyl Impurity | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: 27-O-Desmethyl Everolimus. Grade: > 95%. Molecular formula: C52H81NO14. Mole weight: 944.22. | |
| Everolimus 28-Ethylhydroxy Impurity | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: 28-Ethylhydroxy Rapamycin. Grade: > 95%. Molecular formula: C53H83NO14. Mole weight: 958.25. | |
| Everolimus-d4 | Macrolide immunosuppressant; derivative of Rapamycin. Inhibits cytokine-mediated lymphocyte proliferation. Group: Biochemicals. Alternative Names: 40-O-(2-Hydroxyethyl-d4)rapamycin; 42-O-(2-Hydroxy)ethyl-d4 Rapamycin; Afinitor-d4; Certican-d4; RAD-d4; RAD 001-d4; SDZ-RAD-d4; XIENCE V-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Everolimus-d4 | Everolimus-d 4 is the deuterium labeled Everolimus. Everolimus (RAD001) is a Rapamycin derivative and a potent, selective and orally active mTOR1 inhibitor. Everolimus binds to FKBP-12 to generate an immunosuppressive complex. Everolimus inhibits tumor cells proliferation and induces cell apoptosis and autophagy. Everolimus has potent immunosuppressive and anticancer activities[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: RAD001-d4; SDZ-RAD-d4. CAS No. 1338452-54-2. Pack Sizes: 500 μg. Product ID: HY-10218S. | |
| Everolimus-[d4] | Everolimus-[d4] is the labelled analogue of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: Everolimus D4; 40-O-(2-Hydroxyethyl-d4)rapamycin; 42-O-(2-Hydroxy)ethyl-d4 Rapamycin; Afinitor-d4; Certican-d4; RAD-d4; RAD 001-d4; SDZ-RAD-d4; XIENCE V-d4. Grade: 95% by HPLC; 95% atom D. CAS No. 1338452-54-2. Molecular formula: C53H79D4NO14. Mole weight: 962.25. | |
| Everolimus-D4 solution | 100 ?g/mL in acetonitrile, ampule of 1 mL, certified reference material. Group: Certified reference materials (crms). | |
| Everolimus Dehydrate Impurity | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: Everolimus Dehydro Seco Acid. Grade: > 95%. Molecular formula: C53H83NO14. Mole weight: 958.25. | |
| Everolimus EP Impurity B | An impurity of Everolimus, an mTOR blocker that inhibits the growth of certain cancer. Synonyms: Everolimus 19-Ene Open-Ring Impurity; Everolimus Related Compound 2; seco Everolimus; (19E/Z)-seco-[4-O-(2-Hydroxyethyl)] Rapamycin. CAS No. 1062122-63-7. Molecular formula: C53H83NO14. Mole weight: 958.22. | |
| Everolimus EP Impurity B | Everolimus EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1062122-63-7. Molecular formula: C53H83NO14. Mole weight: 958.24. Catalog: APB1062122637. | |
| Everolimus EP Impurity C | An impurity of Everolimus, an mTOR blocker that inhibits the growth of certain cancer. Synonyms: (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18,19-trihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl]-30-methoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone; 19-O-demethyl everolimus. Molecular formula: C52H81NO14. Mole weight: 944.2. | |
| Everolimus EP Impurity D | An impurity of Everolimus, an mTOR blocker that inhibits the growth of certain cancer. Synonyms: (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1-hydroxy-18-(2-hydroxyethoxy)-12-[(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone; 18-O-hydroxyethyl sirolimus. Molecular formula: C53H83NO14. Mole weight: 958.22. | |
| Everolimus EP Impurity E | An impurity of Everolimus, an mTOR blocker that inhibits the growth of certain cancer. Synonyms: (1R,2R,4S)-4-[(2R)-2-[(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-2,3,10,14,20-pentaoxo-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraen-12-yl]propyl]-2-methoxycyclohexylformate. CAS No. 1237826-25-3. Molecular formula: C52H79NO14. Mole weight: 942.18. | |
| Everolimus EP Impurity E | Everolimus EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Everolimus EP Impurity E. CAS No. 1237826-25-3. Molecular formula: C52H79NO14. Mole weight: 942.18. Catalog: APB1237826253. | |
| Everolimus EP Impurity F | An impurity of Everolimus, an mTOR blocker that inhibits the growth of certain cancer. Synonyms: (1R,9S,12S,15R,16E,18R,19S,20R,21R,23S,24S,25E,27Ξ,28E,30S,32S,35R)-27-ethoxy-1,18,20-trihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36,37-trioxa-4-azatetracyclo[30.3.1.120,24.04,9]heptatriaconta-16,25,28-triene-2,3,10,14-tetrone. Molecular formula: C55H89NO16. Mole weight: 1020.29. | |
| Everolimus Hydrolized Impurity | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: seco Everolimus B; (2S)-1-[2-[(2R,3R,6S)-6-[(2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,20S,21R)-14,20-Dihydroxy-22-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxo-3,5,7,15-docosatetraen-1-yl]tetrahydro-. Grade: > 95%. CAS No. 769905-89-7. Molecular formula: C53H85NO15. Mole weight: 976.27. | |
| Everolimus Impurity 23 (Everolimus-13C2-D4) | Everolimus Impurity 23 (Everolimus-13C2-D4). Uses: For analytical and research use. Group: Impurity standards. CAS No. 1661009-29-5. Molecular formula: C5113C2H79D4NO14. Mole weight: 964.25. Catalog: APB1661009295. | |
| Everolimus Impurity 24 (Everolimus-D4) | Everolimus Impurity 24 (Everolimus-D4). Uses: For analytical and research use. Group: Impurity standards. CAS No. 1338452-54-2. Molecular formula: C53H79D4NO14. Mole weight: 962.26. Catalog: APB1338452542. | |
| Everolimus Impurity 6 | Everolimus Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1704711-12-5. Molecular formula: C54H85NO14. Mole weight: 972.27. Catalog: APB1704711125. | |
| Everolimus Isomer C | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: 9,14-Deepoxy-15-deoxo-14-deoxy-9,15-epoxy-15-hydroxy-42-O-(2-hydroxyethyl)-14-oxorapamycin. Grade: 80%. CAS No. 908340-97-6. Molecular formula: C53H83NO14. Mole weight: 958.25. | |
| Everolimus O-Desmethyl Impurity (Mixture of Diastereomers) | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: 27-O-Desmethyl Everolimus. Grade: > 95%. Molecular formula: C52H81NO14. Mole weight: 944.22. | |
| Everolimus O-Ethyl Impurity | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: 7-O-Desmethyl-7-O-ethyl Everolimus. Grade: > 95%. CAS No. 1704711-12-5. Molecular formula: C54H85NO14. Mole weight: 972.28. | |
| Everolimus O-Silyl Impurity | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: 42-O-tert-Butyldimethylsilyloxyethyl Rapamycin; 42-O-[2-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]ethyl]rapamycin. Grade: > 95%. CAS No. 159351-68-5. Molecular formula: C59H97NO14Si. Mole weight: 1072.52. | |
| Everolimus Related Compound 1 | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: O-Desmethyl Everolimus. Grade: > 95%. CAS No. 745779-75-3. Molecular formula: C52H81NO14. Mole weight: 944.22. | |
| Everolimus Related Compound 3 | Everolimus Ring-Opening Impurity. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: (2S)-1-[[(2R,3R,6S)-6-[(2S,3E,5E,7E,9S,11R)-2,13-Dimethoxy-3,9,11-trimethyl-12-oxo-3,5,7-tridecatrienyl]tetrahydro-2-hydroxy-3-methyl-2H-pyran-2-yl]oxoacetyl]-2-piperidinecarboxylic Acid. Grade: 95%. CAS No. 147438-30-0. Molecular formula: C32H49NO9. Mole weight: 591.75. | |
| Everolimus Related Compound 4 | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: (2S)-1-[2-[(2R,3R,6S)-6-[(2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,20S,21R)-14,20-Dihydroxy-22-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxo-3,5,7,15-docosatetraen-1-yl]tetrahydro-2-hydroxy-3-methyl-. Grade: > 95%. Molecular formula: C57H91NO16. Mole weight: 1046.36. | |
| Everolimus Related Compound 5 | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: Di-tert-butyl-4-methylene-2,5-cyclohexadienone; 2,6-Di-t-butyl-4-methylene-2,5-cyclohexadienone. Grade: > 95%. CAS No. 2607-52-5. Molecular formula: C15H22O. Mole weight: 218.34. | |
| Everolimus Ring-Opening Impurity | An impurity of Everolimus. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Synonyms: Everolimus Retroaldol Degradation Product. Grade: 90% (Mixture of isomers). CAS No. 1708118-13-1. Molecular formula: C53H83NO14. Mole weight: 958.25. | |
| Everolimus solution | 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material. Group: Immunosuppressants. | |
| Evexomostat | Evexomostat is a methionine aminopeptidase 2 (MetAP2) inhibitor. Synonyms: poly({N-[(2RS)-2-hydroxypropyl]methacrylamide}-co-[N-methacryloylgly-cyl-L-phenylalanyl-L-leucyl-N1-(trans-4-{[({(3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-1-oxaspiro[2.5]-octan-6-yl}oxy)carbonyl]amino}cyclohexyl)glycinamide (~0.91:0.09 x)]); poly([N-(2-hydroxypropyl)methacrylamide]-co-{methacryloyl-Gly-Phe-Leu-Gly amide with O-[(trans-4-aminocyclohexyl)carbamoyl]fumagillol}). CAS No. 2416263-67-5. Molecular formula: [(C7H13NO2)n(C46H68N6O10)]m. | |
| Evifacotrep | Evifacotrep is a short transient receptor potential channel 5 (TRPC5) antagonist. Synonyms: 4-chloro-5-{4-[4-fluoro-2-(trifluoromethyl)phenoxy]-5,8-dihydropyrido[3,4-d]pyrimidin-7(6H)-yl}pyridazin-3(2H)-one. CAS No. 2413739-88-3. Molecular formula: C18H12ClF4N5O2. Mole weight: 441.77. | |
| Evinacumab | Evinacumab is a humanized anti-ANGPTL3 monoclonal antibody. Evinacumab has the potential therapeutic activity against homozygous familial hypercholesterolemia. Synonyms: Evkeeza; REGN1500. CAS No. 1446419-85-7. | |
| Evinacumab | Evinacumab (REGN1500) is a human anti- ANGPTL3 ( angiopoietin-like protein 3 ) monoclonal antibody (IgG4 class antibody). Evinacumab reduces plasma lipids in dyslipidemic mice by blocking ANGPTL3. Evinacumab can be used in studies of homozygous familial hypercholesterolaemia (HoFH), refractory hypercholesterolaemia (both familial and non-familial) and severe hypertriglyceridaemia [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN1500. CAS No. 1446419-85-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99194. | |
| Evixapodlin | Evixapodlin is a human programmed cell death ligand 1 (PD-1/PD-L1) protein/protein interaction inhibitor with an IC50 of 0.213 nM. It has anticancer and antiviral functions. Synonyms: (12S,122S)-62,72-dichloro-53,86-dimethoxy-3,10-diaza-5,8(2,5)-dipyrazina-1,12(2)-dipyrrolidina-6,7(1,3)-dibenzenadodecaphane-15,125-dione; (5S,5'S)-5,5'-((((5,5'-(2,2'-dichloro-[1,1'-biphenyl]-3,3'-diyl)bis(3-methoxypyrazine-5,2-diyl))bis(methylene))bis(azanediyl))bis(methylene))bis(pyrrolidin-2-one); 2-Pyrrolidinone, 5,5'-[(2,2'-dichloro[1,1'-biphenyl]-3,3'-diyl)bis[(3-methoxy-5,2-pyrazinediyl)methyleneiminomethylene]]bis-, (5S,5'S)-; PD-1/PD-L1-IN 7. Grade: ≥98%. CAS No. 2374856-75-2. Molecular formula: C34H36Cl2N8O4. Mole weight: 691.61. | |
| Evixapodlin | Evixapodlin (GS-4224) is a human PD-1/PD-L1 protein/protein interaction inhibitor with an IC50 of 0.213 nM. Evixapodlin has anticancer and antiviral functions[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-4224; PD-1/PD-L1-IN 7. CAS No. 2374856-75-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138407. | |
| Evobrutinib | Evobrutinib (M2951) is an orally active, potent, highly selective and irreversibly covalent BTK inhibitor, with an IC 50 of 8.9 nM. Evobrutinib (M2951) can be used for the research of autoimmune diseases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: M2951; MSC2364447C. CAS No. 1415823-73-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101215. | |
| Evocalcet | Evocalcet (KHK7580) is an orally active calcium sensing receptor ( CaSR ) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KHK7580. CAS No. 870964-67-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17613. | |
| Evocalcet | Evocalcet is a calcium-sensing receptor agonist under the development of Kyowa Hakko Kirin. Phase III clinical trials for Secondary hyperparathyroidism are on-going in Japan. Uses: Secondary hyperparathyroidism. Synonyms: MT-4580; MT 4580; MT4580; KHK-7580; KHK7580; KHK 7580; Evocalcet; 2-(4-((S)-3-(((R)-1-(naphthalen-1-yl)ethyl)amino)pyrrolidin-1-yl)phenyl)acetic acid. Grade: 98%. CAS No. 870964-67-3. Molecular formula: C24H26N2O2. Mole weight: 374.48. | |
| Evodenoson | Evodenoson is a selective A2A adenosine receptor agonist. Phase II clinical trials for the treatment of Glaucoma and Ocular hypertension were discontinued. Uses: Glaucoma;ocular hypertension. Synonyms: ATL313; ATL 313; ATL-313; DE-112; DE 112; DE112; methyl 4-[3-[6-amino-9-[(2R,3R,4S,5S)-5-(cyclopropylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]purin-2-yl]prop-2-ynyl]piperidine-1-carboxylate. Grade: 98%. CAS No. 844873-47-8. Molecular formula: C23H29N7O6. Mole weight: 499.53. | |
| Evodenoson | Evodenoson is a selective agonist of the A 2A adenosine receptor. Evodenosons primary actions include reducing inflammatory responses, decreasing intestinal fluid secretion, edema, tissue damage, and neutrophil infiltration induced by Clostridium difficile toxin A. Evodenosons protective effect is achieved by reducing myeloperoxidase (MPO) and adenosine deaminase (ADA) activities, and by lowering the production of tumor necrosis factor-alpha (TNF-α) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ATL 313; DE 112. CAS No. 844873-47-8. Pack Sizes: 1 mg. Product ID: HY-105017. | |
| Evodiamine | Evodiamine - Product ID: NST-10-12. Category: Alkaloids. Alternative Names: d-Evodiamine. Purity: 98%. Test method: HPLC. CAS No. 518-17-2. Pack Sizes: 25g, 50g, 125g, 250g. Appearance: White to pale yellow powder. Molecular formula: C19H17N3O. Mole weight: 303.36. Storage: +2 +8 °C. |  |
| Evodiamine | Evodiamine is an alkaloid isolated from the fruit of Evodia rutaecarpa Bentham with diverse biological activities including anti-inflammatory, anti-obesity, and antitumor. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Evodiamine; d-Evodiamine. CAS No. 518-17-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg. Product ID: HY-N0114. | |
| Evodiamine | A chemical extracted from Evodia plants, and has been shown to reduce fat uptake. Group: Biochemicals. Alternative Names: (13bS)-8, 13, 13b-14-Tetrahydro-14-methyl-indolo[2', 3':3, 4]pyrido[2, 1-b]quinazolin-5(7H)-one; d-Evodiamine; (+)-Evodiamine. Grades: Highly Purified. CAS No. 518-17-2. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| Evodiamine 98% HPLC | Evodiamine 98% HPLC. |  CA, FL & NJ |
| Evofosfamide | Evofosfamide (TH-302) is a hypoxia -activated proagent with IC 50 of 10 μM and 1000 μM in hypoxia (N 2 ) and normoxia (21% O 2 ), respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TH-302. CAS No. 918633-87-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10535. | |
| Evofosfamide | Evofosfamide is a hypoxia-activated prodrug consisting of a 2-nitroimidazole phosphoramidate conjugate with potential antineoplastic activity. The 2-nitroimidazole moiety of hypoxia-activated prodrug TH-302 acts as a hypoxic trigger, releasing the DNA-alkylating dibromo isophosphoramide mustard moiety within hypoxic regions of tumors. Normoxic tissues may be spared due to the hypoxia-specific activity of this agent, potentially reducing systemic toxicity. Synonyms: TH-302; TH 302; TH302; 2-bromo-N-[(2-bromoethylamino)-[(3-methyl-2-nitroimidazol-4-yl)methoxy]phosphoryl]ethanamine. Grade: > 98%. CAS No. 918633-87-1. Molecular formula: C9H16Br2N5O4P. Mole weight: 449.04. | |
| Evogliptin | This active molecular is a selective dipeptidyl peptidase 4 (DPP4) inhibitor under the development of Dong-A. Evogliptin improves insulin resistance and delays the onset of diabetes. Evogliptin monotherapy improved HbA1c, fasting plasma glucose level, OGTT results and β-cell function. In Sep 1st 2016, preclinical trials in Type-2 diabetes mellitus (Combination therapy) in Russia was on-going. In Sep 12th 2016, Phase-I clinical trials in non-alcoholic steatohepatitis (Combination therapy) in USA was on-going. Uses: Type-2 diabetes mellitus. Synonyms: (3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-[(2-methylpropan-2-yl)oxymethyl]piperazin-2-one; CHEMBL1779710; UNII-09118300L7; DA-1229; DA 1229; DA1229; 1222102-29-5; Evogliptin [INN]; 1246960-27-9 (HCl). Grade: 98%. CAS No. 1222102-29-5. Molecular formula: C19H26F3N3O3. Mole weight: 401.43. | |
| Evogliptin hydrochloride | Evogliptin is a DPP-4 inhibitor, for the treatment of type 2 diabetes mellitus in patients with inadequately controlled by diet and exercise alone, or in combination with metformin when diet and exercise plus metformin alone do not provide satisfactory glycaemic control. CAS No. 1246960-27-9. Molecular formula: C19H27ClF3N3O3. Mole weight: 401.42. | |
| Evogliptin tartrate | Evogliptin (DA-1229) tartrate is an orally active DPP4 inhibitor with significant and sustained hypoglycaemic effects in mouse models. Evogliptin tartrate also inhibits the production of inflammatory and fibrotic signals in hepatocytes by inducing autophagy. Evogliptin tartrate can be used in studies of type 2 diabetes, osteoporosis, renal impairment and chronic liver inflammation [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DA-1229 tartrate. CAS No. 1222102-51-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117985B. | |
| Evogliptin Tartrate | Evogliptin is an antidiabetic drug in the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Synonyms: 2-Piperazinone, 4-[(3R)?-3-amino-1-oxo-4-(2,?4,?5-trifluorophenyl)?butyl]?-3-[(1,?1-dimethylethoxy)?methyl]?-, (3R)?-, (2R,?3R)?-2,?3-dihydroxybutanedioat?e (1:1). Grade: > 95%. CAS No. 1222102-51-3. Molecular formula: C19H26F3N3O3. C4H6O6. Mole weight: 401.43 150.09. | |
| Evogliptin Tartrate Impurity S1 | An isomer of Evogliptin. Evogliptin is an antidiabetic drug in the dipeptidyl peptidase-4 (DPP-6) inhibitor class of drugs. Synonyms: 2-Piperazinone, 4-[(3S)?-3-amino-1-oxo-4-(2,?4,?5-trifluorophenyl)?butyl]?-3-[(1,?1-dimethylethoxy)?methyl]?-, (3R)?-, (2R,?3R)?-2,?3-dihydroxybutanedioat?e (1:1). Grade: > 95%. Molecular formula: C19H26F3N3O3. C4H6O6. Mole weight: 401.43 150.09. | |
| Evogliptin Tartrate Impurity S2 | An isomer of Evogliptin. Evogliptin is an antidiabetic drug in the dipeptidyl peptidase-4 (DPP-5) inhibitor class of drugs. Synonyms: 2-Piperazinone, 4-[(3S)?-3-amino-1-oxo-4-(2,?4,?5-trifluorophenyl)?butyl]?-3-[(1,?1-dimethylethoxy)?methyl]?-, (3S)?-, (2R,?3R)?-2,?3-dihydroxybutanedioat?e (1:1). Grade: > 95%. Molecular formula: C19H26F3N3O3. C4H6O6. Mole weight: 401.43 150.09. | |
| Evogliptin Tartrate Impurity S3 | An isomer of Evogliptin. Evogliptin is an antidiabetic drug in the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Synonyms: 2-Piperazinone, 4-[(3R)?-3-amino-1-oxo-4-(2,?4,?5-trifluorophenyl)?butyl]?-3-[(1,?1-dimethylethoxy)?methyl]?-, (3S)?-, (2R,?3R)?-2,?3-dihydroxybutanedioat?e (1:1). Grade: > 95%. Molecular formula: C19H26F3N3O3. C4H6O6. Mole weight: 401.43 150.09. | |
| Evolocumab | Evolocumab is a monoclonal antibody as well as an inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9), a protein targeting LDL receptors. Inhibition of PCSK9 could prevent LDL receptors from degradation and promote the removal of LDL-C from blood circulation. Evolocumab is used for the treatment of hyperlipidemia. Uses: The treatment of hyperlipidemia. Synonyms: AMG 145; AMG-145; AMG145. CAS No. 1256937-27-5. Molecular formula: C6242H9648N1668O1996S56. Mole weight: 141800. | |
| Evolocumab | Evolocumab Inhibitor. Uses: Scientific use. Product Category: T9920. CAS No. 1256937-27-5. |  |
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