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| Product | Description | |
|---|---|---|
| Evolocumab | Evolocumab (AMG 145) is a human monoclonal antibody that inhibits PCSK9. Evolocumab is used in the study of hypercholesterolemia and atherosclerotic cardiovascular disease. Evolocumab binds to circulating PCSK9 protein and inhibits its binding to LDLR. Evolocumab has antioxidant and cytoprotective activities against H 2 O 2 -induced oxidative damage to endothelial cells. Evolocumab may also negatively regulate activation of the TLR-4/NF-κB signaling pathway to prevent inflammation [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AMG 145. CAS No. 1256937-27-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9930. |  |
| Evomonoside | Evomonoside. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-beta-card-20(22)-enolide,3-beta-((6-deoxy-alpha-l-mannopyranosyl)oxy)-14-bet;a-hydroxy-;digitoxigenin3-rhamnoside;digitoxigeninrhamnoside;evomonosid;EVOMONOSIDE;DIGITOXIGENIN-3-O-ALPHA-L-RHAMNOPYRANOSIDE;DIGITOXIGENIN-3-O-A-L-RHAMNOPYRANOSIDE. Product Category: Heterocyclic Organic Compound. CAS No. 508-93-0. Molecular formula: C29H44O8. Mole weight: 520.65. Product ID: ACM508930. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Evomonoside | Evomonoside is a potent natural compound used for studying neurological diseases such as Alzheimer's and Parkinson's. Derived from natural sources, Evomonoside exhibits neuroprotective properties by preventing the formation of amyloid plaques in the brain. Synonyms: (3b,5b)-3-[(6-Deoxy-a-L-mannopyranosyl)oxy]-14-hydroxycard-20(22)-enolide; Digitoxigenin 3-rhamnoside; Digitoxigenin rhamnoside. CAS No. 508-93-0. Molecular formula: C29H44O8. Mole weight: 520.65. |  |
| Evoxanthine | Evoxanthine is a furanoidone alkaloid isolated from Evodia xanthoxyloides. Evoxanthine is active against Gram-positive and Gram-negative bacteria, including Escherichia coli, Bacillus subtilis and Aspergillus flavus. It has antimalarial and anticancer activities. Synonyms: 11-Methoxy-5-Methyl-1,3-Dioxolo[4.5-B]Acridin-10(5H)-One; 1,3-Dioxolo[4.5-B]Acridin-10(5H)-One. Grade: >95% by HPLC. CAS No. 477-82-7. Molecular formula: C16H13NO4. Mole weight: 283.28. | |
| EVP-0015962 | EVP-0015962 is a selective Amyloid precursor protein secretase modulator under the development of FORUM Pharmaceuticals. Chronic treatment with EVP-0015962 can lower the production of Aβ42, attenuate memory deficits, and reduce Aβ plaque formation and inflammation in Tg2576 transgenic animals. EVP-0015962 shows a therapeutic alternative for disease modification in Alzheimer's disease. In Jun 2016, Phase-II for Alzheimer's disease in USA was discontinued. Uses: Alzheimer's disease. Synonyms: EVP-0015962; EVP 0015962; EVP0015962. SCHEMBL3660255; ZSERTYLZGRJLOO-UHFFFAOYSA-N; 2-(5-chloro-6-(2,2,2-trifluoroethoxy)-4'-(trifluoromethyl)biphenyl-3-yl)-3-cyclobutylpropanoic acid. Grade: 98%. CAS No. 1447811-26-8. Molecular formula: C22H19ClF6O3. Mole weight: 480.83. | |
| EVP4593 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| EVP-6124 | EVP-6124 is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs). It shows selectivity for α7 nAChRs and did not activate or inhibit heteromeric α4β2 nAChRs and improves memory performance by potentiating the acetylcholine response of α7 nicotinic acetylcholine receptors. Synonyms: EVP-6124; EVP6124; EVP 6124; MT-4666; MT4666; MT 4666; Encenicline. Grade: >98%. CAS No. 550999-75-2. Molecular formula: C16H17ClN2OS. Mole weight: 320.84. | |
| Evunzekibart | Evunzekibart (ATOR-1017) is an Fc-γ receptor conditional 4-1BB agonist and IgG4-type antibody. Evunzekibart can be used as monotherapy or in combination with anti-PD1 to exert anticancer activity. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ATOR-1017. CAS No. 2639688-77-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990067. | |
| Evuzamitide | Evuzamitide is a diagnostic imaging agent. Evuzamitide as a pan-amyloid radiotracer binding to amyloid deposits from multiple amyloidogenic proteins. Evuzamitide can be used for the research of early diagnosis of amyloid cardiomyopathy (CMP) and monitoring [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 1420048-58-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10023. | |
| EW-7197 | EW-7197 is a potent and selective ALK5 inhibitor, displaying antimetastatic and anticancer effects. It inhibits TGF-β/Smad signaling, and abrogates TGF-β1-induced tumor cell migration and invasion. EW-7197 inhibits breast cancer metastasis to the lung. EW-7197 prolongs the life span of BALB/c 4T1 mice via inhibition of EMT. EW-7197 inhibits metastasis and enhances the activity of cytotoxic T lymphocytes (CTLs) in 4T1 orthotopic grafted mice. Synonyms: Vactosertib; N-(2-fluorophenyl)-5-(6-methyl-2-pyridinyl)-4-[1,2,4]triazolo[1,5-a]pyridin-6-yl-1H-imidazole-2-methanamine. Grade: >98%. CAS No. 1352608-82-2. Molecular formula: C22H18FN7. Mole weight: 399.433. | |
| Ewing Tumor EZH2 (666-674) | Ewing Tumor EZH2 (666-674) is a peptide corresponding to residues 666-674 of Ewing Tumor EZH2. EZH2 in Ewing sarcoma cells directly binds to the promoter regions of genes encoding for two key enzymes of GD2 biosynthesis, and EZH2 inhibition enhances expression of these genes. Synonyms: Ewing Tumor Enhancer of Zeste Homolog 2 (666-674). | |
| EX1314 | BMS-604992 is a selective and orally active growth hormone secretagogue receptor (GHSR) agonist with high-affinity binding (Ki = 2.3 nM) and strong functional activity (EC50 = 0.4 nM). It stimulates feeding in rodents. Synonyms: BMS-604992; Carbamic acid, (2-amino-2-oxoethyl)methyl-, (3-((1S)-1-((2-amino-2-methyl-1-oxopropyl)amino)-2-(phenylmethoxy)ethyl)-1,2,4-triazolo(4,3-a)pyridin-5-yl)methyl ester, monohydrochloride; (3-{(1S)-2-(Benzyloxy)-1-[(2-methylalanyl)amino]ethyl}[1,2,4]triazolo[4,3-a]pyridin-5-yl)methyl (2-amino-2-oxoethyl)methylcarbamate hydrochloride (1:1). Grade: 98%. CAS No. 674343-47-6. Molecular formula: C24H32ClN7O5. Mole weight: 534.01. | |
| EX229 | EX229 (compound 991), also known as AMPK Activator 991, is a potent AMPK activator that displays 5-10-fold more potent than A769662 in activating AMPK. Synonyms: Compound 991; AMPK Activator 991; 5-[[6-chloro-5-(1-methylindol-5-yl)-1H-benzimidazol-2-yl]oxy]-2-methylbenzoic acid. Grade: ≥98%. CAS No. 1219739-36-2. Molecular formula: C24H18ClN3O3. Mole weight: 431.87. | |
| EX229 | EX229, a Benzimidazole derivative, is a potent and allosteric activator of AMP-activated protein kinase (AMPK), with Kds of 0.06 ?M, 0.06 ?M and 0.51 ?M for ?1?1?1, ?2?1?1 and ?1?2?1 in biolayer interferometry, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1219739-36-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-112769. | |
| Ex26 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Ex26 | Ex26 (S1P1-IN-Ex26) is a potent and selective sphingosine 1-phosphate receptor 1 ( S1P 1 ) antagonist ( IC 50=0.93 nM). Ex26 shows >3,000-fold selectivity for S1P 1 over other Sphingosine 1-phosphate receptors. Ex26 can be used in experimental autoimmune encephalomyelitis reseach [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S1P1-IN-Ex26. CAS No. 1233332-37-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-117213. | |
| Ex 26 | Ex 26 is a potent and selective S1P1 receptor antagonist (IC50 = 0.93 nM) with > 3,000-fold selectivity over S1P2, S1P3, S1P4 and S1P5. It causes lymphocyte sequestration in peripheral lymph nodes, and upregulates S1P1 receptor expression. Synonyms: 1-[[[5'-[[1-(4-Chloro-3-methylphenyl)ethyl]amino]-2'-fluoro-3,5-dimethyl[1,1'-biphenyl]-4-yl]carbonyl]amino]-cyclopropanecarboxylic acid. Grade: ≥98% by HPLC. CAS No. 1233332-37-0. Molecular formula: C28H28ClFN2O3. Mole weight: 494.98. | |
| EX 527 | EX 527. Group: Biochemicals. Grades: Purified. CAS No. 49843-98-3. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| EX-527 | EX-527 Inhibitor. Uses: Scientific use. Product Category: T6111. CAS No. 49843-98-3. |  |
| EX-527 | EX 527 is a potent and selective SIRT1 inhibitor with IC50 of 38 nM, exhibits >200-fold selectivity against SIRT2 and SIRT3. Synonyms: SEN0014196; EX-527; EX-527; EX-527; Selisistat. Grade: >98%. CAS No. 49843-98-3. Molecular formula: C13H13ClN2O. Mole weight: 248.71. | |
| EX-527 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| EX-527 R-enantiomer | EX-527 R-enantiomer is the R-enantiomer of EX-527, which is a potent and selective SIRT1 inhibitor and with no inhibition on SIRT3 and SIRT3. It is a negative control of the active form EX-527 S-enantiomer. Synonyms: Selisistat R-enantiomer; (R)-Selisistat; EX-527(R); EX 527(R); EX527(R). Grade: >98%. CAS No. 848193-69-1. Molecular formula: C13H13ClN2O. Mole weight: 248.71. | |
| EX 527 (Selisistat, EX527, SIRT1 Inhibitor III) | EX 527 (Selisistat, EX527, SIRT1 Inhibitor III). Group: Biochemicals. Alternative Names: 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide. Grades: Highly Purified. CAS No. 49843-98-3. Pack Sizes: 10mg. Molecular Formula: C13 H13 ClN 2, Molecular Weight: 248.7. US Biological Life Sciences. | Worldwide |
| EX-527 S-enantiomer | EX-527 S-enantiomer is the S-enantiomer of EX-527, which is a potent and selective SIRT1 inhibitor and with no inhibition on SIRT3 and SIRT3. Synonyms: Selisistat S-enantiomer; EX-527(S); (S)-Selisistat; EX 527(S); EX527(S); EX-527S; EX527S. Grade: >98%. CAS No. 848193-68-0. Molecular formula: C13H13ClN2O. Mole weight: 248.71. | |
| EX-527, SIRT1 Inhibitor (6-Chloro-2,3,4,9-tetrahydro-1Hcarbazole- 1-carboxamide (racemic)) | Selective SIRT1 inhibitor (IC50=98nM). Does not inhibit other HDACs or SIRT family members. Group: Biochemicals. Alternative Names: 6-Chloro-2,3,4,9-tetrahydro-1Hcarbazole- 1-carboxamide (racemic). Grades: Highly Purified. CAS No. 49843-98-3. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| Exalamide | Exalamide (2-(Hexyloxy)benzamide), an arenecarboxamide, is a potent antifungal agent. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-(hexyloxy)-benzamid;2-n-hexyloxybenzamide;h.p.216;o-hexyloxy-benzamid;2-(HEXYLOXY)BENZAMIDE;HBA;HYPERAN;EXALAMIDE. Product Category: Inhibitors. Appearance: White Solid. CAS No. 53370-90-4. Molecular formula: C13H19NO2. Mole weight: 221.3. Purity: 0.9993. Canonical SMILES: O=C(N)C1=CC=CC=C1OCCCCCC. Density: 1.03 g/cm³. Product ID: ACM53370904. Alfa Chemistry ISO 9001:2015 Certified. | |
| Exalamide | Exalamide. Group: Biochemicals. Alternative Names: HBA, hyperan, 2-(hexyloxy)benzamide. Grades: Highly Purified. CAS No. 53370-90-4. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C13H19NO2. US Biological Life Sciences. | Worldwide |
| Exalamide | Exalamide is a derivative of salicylamide used as an antifungal. Uses: Used as an antifungal. Synonyms: 2-(Hexyloxy)benzamide; 2-hexoxybenzamide. Grade: ≥95%. CAS No. 53370-90-4. Molecular formula: C13H19NO2. Mole weight: 221.3. | |
| Exaltenone | Exaltenone. CAS No. 14595-54-1. VIGON Item # 502773. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers, (Z)-musk pentane. |  America & Internationally |
| Exaltolide® | Exaltolide®. CAS No. 106-02-5. FEMA No. 2840. Kosher: Y. VIGON Item # 502774. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers, omega-pentadecalactone. | America & Internationally |
| Exaltolide® Total | Exaltolide® Total. CAS No. 106-02-5. FEMA No. 2840. Kosher: Y. VIGON Item # 502775. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers. | America & Internationally |
| Exaluren disulfate | Exaluren (ELX-02) disulfate is an investigational, advanced synthetic eukaryotic ribosome selective glycoside (ERSG). Exaluren disulfate is being developed as a therapy for genetic diseases caused by nonsense mutations[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ELX-02 disulfate; NB-124 disulfate. CAS No. 2244622-33-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-114231B. | |
| Exarafenib | Exarafenib (RAF/KIN_2787) is an orally-available, selective pan-RAF inhibitor. Exarafenib is effective in RAF-dependent cancers, including all classes of BRAF alterations. Exarafenib suppresses MAPK signaling in RAF-dependent melanoma cell lines. Exarafenib has anticancer activity[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RAF/KIN_2787. CAS No. 2639957-39-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147268. | |
| Exatecan | Exatecan (DX-8951) is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 10H,13H-BENZO[DE]PYRANO[3,4:6,7]INDOLIZINO[1,2-B]QUINOLINE-10,13-DIONE, 1-AMINO-9-ETHYL-5-FLUORO-1,2,3,9,12,15-HEXAHYDRO-9-HYDROXY-4-METHYL-, (1S,9S)-, MONOMETHANESULFONATE (SALT);exatecan alideximer;(1S,9S)-1-Amino-9-ethyl-5-fluoro-1,2,3,9,12,15-hexahydro-9-hydroxy-4-methyl-10H,13H-benzo(de)pyrano(3,4:6,7)indolizino(1,2-b)quinoline-10,13-dione;Exatecan;DX 8951. Product Category: Inhibitors. CAS No. 171335-80-1. Molecular formula: C24H22FN3O4. Mole weight: 435.45. Purity: 0.994. Product ID: ACM171335801. Alfa Chemistry ISO 9001:2015 Certified. | |
| Exatecan | Exatecan (DX-8951) is a DNA topoisomerase I inhibitor, with an IC 50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DX-8951. CAS No. 171335-80-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13631. | |
| Exatecan | Exatecan is an inhibitor of DNA topoisomerase I, with an IC50 of 2.2 μM (0.975 μg/mL). It can be used to study cancer. Uses: Topoisomerase i inhibitors. Synonyms: DX-8951; (1S,9S)-1-Amino-9-ethyl-5-fluoro-1,2,3,9,12,15-hexahydro-9-hydroxy-4-methyl-10H,13H-benzo(de)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-10,13-dione; 10H,13H-Benzo(de)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-10,13-dione, 1-amino-9-ethyl-5-fluoro-1,2,3,9,12,15-hexahydro-9-hydroxy-4-methyl-, (1S-trans)-; NSC-829066. Grade: ≥95%. CAS No. 171335-80-1. Molecular formula: C24H22FN3O4. Mole weight: 435.45. | |
| Exatecan-d5 mesylate | Exatecan-d5 (DX8951f-d5) mesylate is deuterium labeled Exatecan mesylate (HY-13631A). Exatecan mesylate is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 ?M (0.975 ?g/mL). Exatecan mesylate can be used in cancer research[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: DX8951f-d5; Deuterated labeled Exatecan mesylate. CAS No. 2819276-88-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13631AS. | |
| Exatecan free base | Exatecan, also known as DX 8951, is a semisynthetic, water-soluble derivative of camptothecin with antineoplastic activity. Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death. This agent does not require enzymatic activation and exhibits greater potency than camptothecin and other camptothecin analogues. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DX 8951; DX 8951; DX 8951; Exatecan free base. Product Category: Others. Appearance: Solid powder. CAS No. 171335-80-1. Molecular formula: C24H22FN3O4. Mole weight: 435.46. Purity: >98%. IUPACName: (1S,9S)-1-Amino-9-ethyl-5-fluoro-1,2,3,9,12,15-hexahydro-9-hydroxy-4-methyl-10H,13H-benzo(de)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-10,13-dione. Canonical SMILES: O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=C5C6=C(CC[C@@H]5N)C(C)=C(F)C=C6N=C4C3=C2)=O. Product ID: ACM171335801-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| Exatecan mesilate hydrate | Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death. Synonyms: Exatecan methanesulfonate dihydrate; DX 8951 mesilate hydrate. CAS No. 197720-53-9. Molecular formula: C25H30FN3O9S. Mole weight: 567.58. | |
| Exatecan mesylate | Exatecan mesylate (DX8951f) is a DNA topoisomerase I inhibitor, with an IC 50 of 2.2 μM (0.975 μg/mL). Exatecan mesylate can be used in cancer research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DX8951f. CAS No. 169869-90-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-13631A. | |
| Exatecan Mesylate | Exatecan mesylate is a semisynthetic, water-soluble derivative of camptothecin with antineoplastic activity. Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting the religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death. This agent does not require enzymatic activation and exhibits greater potency than camptothecin and other camptothecin analogs. Synonyms: DX 8951 mesylate; (1S,9S)-1-Amino-9-ethyl-5-fluoro-1,2,3,9,12,15-hexahydro-9-hydroxy-4-methyl-10H,13H-benzo(de)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-10,13-dione mesylate; 10H,13H-Benzo(de)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-10,13-dione, 1-amino-9-ethyl-5-fluoro-1,2,3,9,12,15-hexahydro-9-hydroxy-4-methyl-, (1S-trans)-, mesylate (1:1); NSC-829066 mesylate. Grade: >98%. CAS No. 169869-90-3. Molecular formula: C25H26FN3O7S. Mole weight: 531.56. | |
| Exatecan (mesylate) (GMP) | Exatecan mesylate (DX8951f ) GMP is a GMP-class Exatecan (HY-13631). Exatecan is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 ?M (0.975 ?g/mL), and can be used in cancer research[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DX8951f (GMP). CAS No. 169869-90-3. Pack Sizes: 10 mg; 50 mg; 100 mg. Product ID: HY-13631AG. | |
| Exatecan (Standard) | Exatecan (Standard) is the analytical standard of Exatecan. This product is intended for research and analytical applications. Exatecan (DX-8951) is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 ?M (0.975 ?g/mL), and can be used in cancer research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DX-8951 (Standard). CAS No. 171335-80-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13631R. | |
| Exbivirumab | Exbivirumab is a human monoclonal antibody that targets hepatitis B surface antigen. Exbivirumab has the potential for the treatment of hepatitis B infections. Grade: 95%. CAS No. 569658-80-6. Molecular formula: C15H11BrClNO2S. Mole weight: 384.7. | |
| Excess aluminum Ti3AlC2 MXene | Excessive aluminum Ti3AlC2 and rich aluminum lead to improved structural order and morphology of Ti3AlC2 grains, while also reducing oxygen activity, producing the highest stoichiometric MAX phase without affecting the quality of the obtained MXene. Uses: Hot press, mxene precursor. Group: Mxenes materials. |  |
| Exchange Reaction Buffer 10X | Exchange reaction buffer (10X) for P4410. Group: Molecular Biology. Alternative Names: For use with T4 polynucleotide kinase. Pack Sizes: 200ul, 1x1ml. US Biological Life Sciences. | Worldwide |
| Excisanin A | Excisanin A is a natural diterpenoid compound found in several plants. Synonyms: 1alpha,7alpha,12alpha,14beta-Tetrahydroxy-ent-kaur-16-en-15-one. Grade: >95%. CAS No. 78536-37-5. Molecular formula: C20H30O5. Mole weight: 350.45. | |
| Excisanin B | Excisanin B is extracted from the herbs of Isodon japonicus. It inhibits production of nitric oxide in LPS-induced murine macrophage RAW264.7 cells. Synonyms: 1alpha,7alpha,14beta-Trihydroxy-12alpha-acetoxykaura-16-ene-15-one. Grade: 98.0%. CAS No. 78536-36-4. Molecular formula: C22H32O6. Mole weight: 392.49. | |
| Exemestane | Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC 50 s of 30 nM and 40 nM for human placenta l and rat ovarian aromatase , respectively. Exemestane can be used for hormone-dependent breast cancer research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FCE 24304; EXE. CAS No. 107868-30-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13632. | |
| Exemestane-19-d3 (6-Methyleneandrosta-1,4-diene-3,17-dione-19-d3, FCE 24304-19-d3, Aromasin-19-d3) | An antineoplastic (hormonal). Group: Biochemicals. Alternative Names: 6-Methyleneandrosta-1,4-diene-3,17-dione-19-d3;FCE 24304-19-d3; Aromasin-19-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Exemestane (6-Methyleneandrosta-1,4-diene-3,17-dione, FCE-24304, Aromasin) | An antineoplastic (hormonal). Group: Biochemicals. Alternative Names: 6-Methyleneandrosta-1,4-diene-3,17-dione, FCE-24304, Aromasin. Grades: Highly Purified. CAS No. 107868-30-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Exemestane-[d2] | Exemestane-[d2] is a deuterium labelled analogue of Exemestane. Exemestane is a medication used for the treatment of certain types of breast cancer. It acts via inhibiting estrogen essential for some breast cancers' growth. Synonyms: 6-Methyleneandrosta-1,4-diene-3,17-dione-16,16-D2; Exemestane D2; (8R,9S,10R,13S,14S)-10,13-dimethyl-6-methylene-7,8,9,10,11,12,13,14,15,16-decahydro-3H-cyclopenta[a]phenanthrene-3,17(6H)-dione-16,16-d2; Aromasin-d2; Aromasine-d2; Exemestano-d2. Grade: 99.6% by HPLC; 99% atom D. Molecular formula: C20H22D2O2. Mole weight: 298.38. | |
| Exemestane-d3 | One of the isotopic labelled form of Exemestane, which is a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6-Methyleneandrosta-1,4-diene-3,17-dione-d3. Molecular formula: C20H21O2D3. Mole weight: 299.43. | |
| Exemestane-d5 | One of the isotopic labelled form of Exemestane, which is a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6-Methyleneandrosta-1,4-diene-3,17-dione-d5. Molecular formula: C20H19O2D5. Mole weight: 301.44. | |
| Exemestane EP Impurity H | Exemestane EP Impurity H. Uses: For analytical and research use. Group: Impurity standards. CAS No. 122370-91-6. Molecular formula: C20H26O2. Mole weight: 298.43. Catalog: APB122370916. | |
| Exemestane Impurity 1 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 1,2-α-Epoxy Exemestane; (1α,2α)-1,2-Epoxy-6-methyleneandrost-4-ene-3,17-dione. Grade: > 95%. CAS No. 159354-61-7. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Exemestane Impurity 11 | Exemestane Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 107868-36-0. Molecular formula: C20H23ClO2. Mole weight: 330.85. Catalog: APB107868360. | |
| Exemestane Impurity 13 | Exemestane Impurity 13. Uses: For analytical and research use. Group: Impurity standards. CAS No. 152764-29-9. Molecular formula: C20H26O3. Mole weight: 314.43. Catalog: APB152764299. | |
| Exemestane Impurity 3 | Exemestane Impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1012054-48-6. Molecular formula: C20H28O3. Mole weight: 316.44. Catalog: APB1012054486. | |
| Exemestane Impurity 3 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6,16-Dimethylideneandrosta-1,4-diene-3,17-dione. Grade: > 95%. Molecular formula: C21H24O2. Mole weight: 308.42. | |
| Exemestane Impurity 4 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 16-methylideneandrosta-1,4-diene-3,17-dione. Grade: > 95%. Molecular formula: C20H24O2. Mole weight: 296.41. | |
| Exemestane Impurity 6 | Exemestane Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1331732-05-8. Molecular formula: C20H26O3. Mole weight: 314.43. Catalog: APB1331732058. | |
| Exemestane Impurity 8 (Testosterone Impurity 6) | Exemestane Impurity 8 (Testosterone Impurity 6). Uses: For analytical and research use. Group: Impurity standards. CAS No. 1035-69-4. Molecular formula: C19H24O2. Mole weight: 284.4. Catalog: APB1035694. | |
| Exemestane Impurity E | Exemestane Impurity E. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2'R,8R,9S,10R,13S,14S)-10,13-dimethyl-7,8,9,11,12,13,15,16-octahydrospiro[cyclopenta[a]phenanthrene-6,2'-oxirane]-3,17(10H,14H)-dione. CAS No. 152764-24-4. Molecular formula: C20H24O3. Mole weight: 312.4. Catalog: APB152764244. | |
| Exemestane Impurity G | Exemestane Impurity G. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2'S,8R,9S,10R,13S,14S)-10,13-dimethyl-7,8,9,11,12,13,15,16-octahydrospiro[cyclopenta[a]phenanthrene-6,2'-oxirane]-3,17(10H,14H)-dione. CAS No. 152764-31-3. Molecular formula: C20H24O3. Mole weight: 312.4. Catalog: APB152764313. | |
| Exemestane Metabolite 1 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 17β-Hydroxy Exemestane Sulfamate; (17β)-17-[(Aminosulfonyl)oxy]-6-methyleneandrosta-1,4-dien-3-one. Grade: > 95%. Molecular formula: C20H27NO4S. Mole weight: 377.51. | |
| Exemestane Metabolite 2 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6-Hydroxy-6-(methoxymethyl)-androsta-1,4-diene-3,17-dione. Grade: > 95%. Molecular formula: C21H28O4. Mole weight: 344.45. | |
| Exemestane Related Compound | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6α-(Methoxymethyl)androsta-1,4-dien-3,17-dione. Grade: > 95%. CAS No. 881896-95-3. Molecular formula: C21H28O3. Mole weight: 328.46. | |
| Exemestane Related Compound 1 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 6β-(Formyl)androsta-1,4-dien-3,17-dione. Grade: > 95%. Molecular formula: C20H24O3. Mole weight: 312.41. | |
| Exemestane Related Compound 2 | A metabolite of Exemestane. Exemestaneis a third generation, irreversible steroidal aromatase inhibitor that induces aromatase degradation leading to a decrease in estrogen levels in plasma. Synonyms: 17-hydroxy-8,10,13-trimethyl-3-oxo--decahydro-3H-cyclopenta[a]phenanthrene-6-carboxylic acid. Grade: > 95%. Molecular formula: C20H24O3. Mole weight: 312.41. | |
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