A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Futuximab is a chimeric monoclonal antibody directed against EGFR. Futuximab has been used in the research of cancer therapy. Grade: 95%. CAS No. 1310460-85-5. Molecular formula: C6468H10002N1724O2055S46. Mole weight: 146.3 kDa.
Futuximab
Futuximab is a chimeric monoclonal antibody targeting non-overlapping epitopes on EGFR. Futuximab has antineoplastic activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1310460-85-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99628.
Fuzapladib
Fuzapladib (IS-741), an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IS-741. CAS No. 141283-87-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19151.
Fuzapladib sodium
Fuzapladib (IS-741) sodium, an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib sodium is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib sodium exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IS-741 sodium. CAS No. 141284-73-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19151A.
Fuziline
Fuziline. Group: Biochemicals. Alternative Names: 15-Hydroxyneoline; 15-Epinagarine; Senbusine C. Grades: Plant Grade. CAS No. 80665-72-1. Pack Sizes: 20mg. Molecular Formula: C24H39NO7, Molecular Weight: 453.569. US Biological Life Sciences.
Worldwide
Fuzuloparib
Fuzuloparib is a poly (ADP-ribose) polymerase (PARP) inhibitor potentially for the treatment of solid tumours. Synonyms: 4-({4-fluoro-3-[2-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[1,5-a]pyrazine-7(8H)-carbonyl]phenyl}methyl)phthalazin-1(2H)-one; 1(2H)-Phthalazinone, 4-[[3-[[5,6-dihydro-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrazin-7(8H)-yl]carbonyl]-4-fluorophenyl]methyl]-; Fuzuopali; SHR-3162; Fuzuloparibum. Grade: ≥98%. CAS No. 1358715-18-0. Molecular formula: C22H16F4N6O2. Mole weight: 472.40.
FW1256
Exogenous H2S, as we know, has anti-inflammatory effects both in macrophages and in animal models. FW1256 is a slow release H2S dononr and it is much more potent in cells. FW1256 may be useful for studies of H2S in biology and could also have future therapeutic value in inflammatory conditions. Uses: Anti-inflammation. Synonyms: FW1256; FW-1256; FW 1256. 2-phenyl-3H-benzo[d][1,3,2]oxazaphosphole 2-sulfide. Grade: 98%. CAS No. 117089-08-4. Molecular formula: C12H10NOPS. Mole weight: 247.25.
FX1
FX1 is a selective inhibitor of B cell lymphoma 6 (BCL6) (IC50 = 35 μM in reporter assays), which can disrupt formation of the BCL6 repression complex, reactivate BCL6 target genes and mimick the phenotype of mice engineered to express BCL6 with corepressor binding site mutations. FX1 also inhibits ABC-DLBCL cells. Synonyms: FX1; FX-1; FX 1. SCHEMBL16323186; CHEBI:133537; AKOS015865677; CS-7688; HY-102027; 3-[(5Z)-5-(5-chloro-2-oxo-1H-indol-3-ylidene)-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]propanoic acid. Grade: 99.75 %. CAS No. 1426138-42-2. Molecular formula: C14H9ClN2O4S2. Mole weight: 368.82.
FX1
FX1 is a potent and specific BCL6 inhibitor, with an IC 50 of around 35 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1426138-42-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-102027.
FX-11 is a potent, selective, reversible and competitive lactate dehydrogenase A (LDHA) inhibitor, with a Ki of 8 ?M. FX-11 reduces ATP levels and induces oxidative stress, ROS production and cell death. FX-11 shows antitumor activity in lymphoma and pancreatic cancer xenografts[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LDHA Inhibitor FX11. CAS No. 213971-34-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16214.
FX-909
FX-909 is a covalent peroxisome proliferator-activated receptor gamma ( PPARG ) inverse agonist. FX-909 can be used for the research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2924573-90-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153344.
FXIIIa-IN-1 sodium
C.I.Reactive Black 5 (Technical Grade) is a biological molecule. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Reactive Black 5. CAS No. 17095-24-8. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-W783421.
FXR/TGR5 agonist 1
FXR/TGR5 agonist 1, a dual agonist of FXR and TGR5, can be used to treat fatty liver disease. Synonyms: N-(3-chloro-5-methoxyphenyl)-N-((4-(3-cyano-4-methoxyphenyl)bicyclo[2.2.2]octan-1-yl)methyl)-3-methylisonicotinamide. CAS No. 2677689-72-2. Molecular formula: C31H32ClN3O3. Mole weight: 530.06.
FY26 (complex)
This active moleculr is a Os(II) anticancer drug candidate. It can generate reactive oxygen species and disrupt the redox balance in cancer cells. Using FY26 and nontoxic doses of L-BSO together allows the potentiation of its anticancer activity and inpartantly, it improves the selectivity for cancer cells versus normal fibroblasts. FY26 can shut down a cancer cell by exploiting weaknesses inherent in their energy generation. Uses: Anti-cancer. Synonyms: FY26; FY-26; FY 26. Osmium(1+)?, [N,?N-dimethyl-4-[2-(2-pyridinyl-κN)?diazenyl-κN1]?benzenamine]?iodo[(1,?2,?3,?4,?5,?6-η)?-1-methyl-4-(1-methylethyl)?benzene]?-, hexafluorophosphate(?1-) (1:1). Grade: 98%. CAS No. 1255143-82-8. Molecular formula: C23H28F6IN4OsP. Mole weight: 822.60.
Fz7-21, a peptide antagonist of Frizzled 7 receptor, selectively binds to Frizzled 7 CRD subclass. Synonyms: FZD7 binding peptide; Ac-Leu-Pro-Ser-Asp-Asp-Leu-Glu-Phe-Trp-Cys-His-Val-Met-Tyr-NH2. Grade: ≥97% by HPLC. CAS No. 2247635-23-8. Molecular formula: C83H114N18O23S2. Mole weight: 1796.05.
FzM1
FzM1 is a negative allosteric modulator (NAM) of Frizzled receptor FZD4. FzM1 reduces WNT5A-dependent WNT responsive element (WRE) activity (log EC 50inh =-6.2). FzM1 binds to an allosteric binding site located in intracellular loop 3 (ICL3) of FZD4 and alters the conformation of the receptor, ultimately inhibiting the WNT/β-catenin cascade [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1680196-54-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116553.