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Fmoc-ACA-OH is a useful tool for the SPPS of AMC fluorogenic protease substrates by Fmoc SPPS. Fmoc-ACA-OH must be first loaded onto a Wang-type resin. Any unreacted linker hydroxyls must be capped using acetic anhydride. Following Fmoc removal, the first amino acid should be coupled with HATU/collidine. Insertion of ACA into the middle of a peptide provides fluorogenic substrates for endopeptidases. Treatment of the ACC peptide obtained after TFA cleavage with an aqueous base causes facile decarboxylation and formation of the AMC peptide. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-ACA-OH, 7-N-Fmoc-aminocoumarin-4-acetic acid. Product Category: Amino Acids. CAS No. 378247-75-7. Mole weight: 441.43. Product ID: ACM378247757. Alfa Chemistry ISO 9001:2015 Certified.
A backbone for PNA synthesis. Synonyms: N-[2-[[ (9H-Fluoren-9-ylmethoxy) carbonyl]amino]ethyl]glycine methyl ester. Grades: 98%. CAS No. 156939-69-4. Molecular formula: C20H22N2O4. Mole weight: 354.41.
Fmoc-Aeg-OtBu HCl
A backbone for PNA synthesis. Synonyms: N-[2-(Fmoc-amino)-ethyl]-Gly-OtBu HCl; tert-Butyl[2-(Fmoc-amino)ethylamino]acetate hydrochloride; N-[2-(Fmoc-amino)-ethyl]glycine tert-butylester hydrochloride; tert-Butyl [2-(Fmoc-amino)ethylamino]acetate hydrochloride; N-[2-(FMOC-AMINO)-ETHYL]-GLY-O-TBU HCl. Grades: 98%. CAS No. 169396-88-7. Molecular formula: C23H28N2O4·HCl. Mole weight: 432.95.
Fmoc-Agp(Boc)2-OH
Fmoc-Agp(Boc)2-OH. Group: Biochemicals. Alternative Names: (S)-N-Fmoc-N,N'-bis-Boc-2-amino-3-guanidino propionic acid. Grades: Highly Purified. CAS No. 313232-63-2. Pack Sizes: 100mg, 250mg, 500mg, 1g. US Biological Life Sciences.
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Fmoc-Agp(Boc)2-OH
Fmoc-Agb(Boc)2-OH is a useful tool for the introduction of shortened arginine analog, Agb, during Fmoc SPPS. It can be used in exactly the same manner as Fmoc-Arg(Pbf)-OH. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Agp(Boc)2-OH, N-α-Fmoc-N,NÆ-γ-di-t.-butoxycarbonyl-L-diaminobutanoic acid. Product Category: Amino Acids. CAS No. 313232-63-2. Mole weight: 568.62. Product ID: ACM313232632-1. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Agp(Boc)2-OH ≥97% (HPLC)
Fmoc-Agp(Boc)2-OH ≥97% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences.
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Fmoc-Aib-OH
Fmoc-Aib-OH is an alanine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 94744-50-0. Pack Sizes: 25 g; 100 g. Product ID: HY-79648.
Fmoc-Aib-OH
Standard building block for introduction of aminoisobutyric amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Aib-OH, N-α-Fmoc-α-aminoisobutyric acid, N-Fmoc-C-α-methylalanine, Fmoc-alpha-aminoisobutyric acid. Product Category: Amino Acids. CAS No. 94744-50-0. Molecular formula: C19H19NO4. Mole weight: 325.36. Product ID: ACM94744500. Alfa Chemistry ISO 9001:2015 Certified. Categories: EC 619-072-5.
Fmoc-Ala-Ala-OH
Fmoc-Ala-Ala-OH. Group: Biochemicals. Alternative Names: Fmoc-L-alanyl-L-alanine. Grades: Highly Purified. CAS No. 87512-31-0. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. US Biological Life Sciences.
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Fmoc-Ala-Ala-OH
Fmoc-Ala-Ala-OH (3) is a self-assemble fluorenylmethoxycarbonyl-dipeptide, which is a smaller amphiphilic building blocks consists dipeptides linked to fluore nylmethoxycarbonyl (Fmoc). Fmoc-Ala-Ala-OH can be used as scaffold materials in 3D cell culture [1]. Uses: Scientific research. Group: Peptides. CAS No. 87512-31-0. Pack Sizes: 5 g; 10 g; 25 g; 100 g. Product ID: HY-W048825.
Fmoc-Ala-Ala-OH 99+%
Fmoc-Ala-Ala-OH 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g, 25g. US Biological Life Sciences.
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Fmoc-Ala-Ala-PAB
Fmoc-Ala-Ala-PAB is a cleavable ADC linker. Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1384263-83-5. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-148462.
Fmoc-Ala-OH is an alanine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 35661-39-3. Pack Sizes: 100 g; 500 g. Product ID: HY-W009204.
Fmoc-Ala-OH
High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities. Standard building block for introduction of alanine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Ala-OH, N-α-Fmoc-L-alanine monohydrate. Product Category: Amino Acids. CAS No. 35661-39-3. Molecular formula: C18H17NO4. Mole weight: 311.33. Product ID: ACM35661393. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Ala-OH (1-13C)
Fmoc-Ala-OH (1-13C). Uses: Peptide synthesis. Additional or Alternative Names: N-(9-Fluorenylmethoxycarbonyl)-L-alanine-1-13C, L-Alanine-1-13C, N-Fmoc. Product Category: Amino Acids. CAS No. 202326-53-2. Molecular formula: CH3CH(NH-Fmoc)13COOH. Mole weight: 312.3. Purity: 99 atom % 13C. Canonical SMILES: C[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)[13C](O)=O. Product ID: ACM202326532-2. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Ala-OH-1-13C
Fmoc-Ala-OH-1-13C. Uses: Peptide synthesis. Additional or Alternative Names: N-(9-Fluorenylmethoxycarbonyl)-L-alanine-1-13C, L-Alanine-1-13C, N-Fmoc. Product Category: Amino Acids. CAS No. 202326-53-2. Molecular formula: CH3CH(NH-Fmoc)13CO2H. Mole weight: 312.32. Canonical SMILES: C[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)[13C](O)=O. Product ID: ACM202326532-3. Alfa Chemistry ISO 9001:2015 Certified. Categories: Fmoc-Ala-OH (1-13C).
Fmoc-Ala-OH (15N)
Fmoc-Ala-OH (15N). Uses: Peptide synthesis. Additional or Alternative Names: N-(9-Fluorenylmethoxycarbonyl)-L-alanine-15N, L-Alanine-15N, N-Fmoc. Product Category: Amino Acids. CAS No. 117398-49-9. Molecular formula: CHCH(15NH-Fmoc)COOH. Mole weight: 312.3. Purity: 98 atom % 15N. Canonical SMILES: C[C@H]([15NH]C(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O. Product ID: ACM117398499-2. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Ala-OH-15N
Fmoc-Ala-OH-15N. Uses: Peptide synthesis. Additional or Alternative Names: N-(9-Fluorenylmethoxycarbonyl)-L-alanine-15N, L-Alanine-15N, N-Fmoc. Product Category: Amino Acids. CAS No. 117398-49-9. Molecular formula: CH3CH(15NH-Fmoc)CO2H. Mole weight: 312.33. Canonical SMILES: C[C@H]([15NH]C(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O. Product ID: ACM117398499-3. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Ala-OH-[15N]
Fmoc-Ala-OH-[15N] is a labelled Fmoc-Ala-OH. Alanine is one of the non-essential amino acids for humans. Alanine is the key compound in glucose-alanine cycle. Synonyms: N-(9-Fluorenylmethoxycarbonyl)-L-alanine-15N; Fmoc-Ala-OH (15N); Fmoc-Ala-OH-15N. Grades: 98% by HPLC; 98% atom 15N. CAS No. 117398-49-9. Molecular formula: C18H17[15N]O4. Mole weight: 312.33.
Fmoc-Ala-OH (3-13C)
Fmoc-Ala-OH (3-13C) is a Fmoc-protected alanine derivative that is potentially useful for proteomics studies and solid-phase peptide synthesis techniques. Uses: Peptide synthesis. Additional or Alternative Names: N-(9-Fluorenylmethoxycarbonyl)-L-alanine-3-13C, L-Alanine-3-13C, N-Fmoc. Product Category: Amino Acids. CAS No. 201489-21-6. Molecular formula: 13CH3CH(NH-Fmoc)COOH. Mole weight: 312.3. Purity: 99 atom % 13C. Canonical SMILES: [13CH3][C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O. Product ID: ACM201489216-2. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Ala-OH-3-13C
Fmoc-Ala-OH-3- 13 C is the 13 C labeled Fmoc-Ala-OH[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 201489-21-6. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W009204S3.
Fmoc-Ala-OH-3-13C
Fmoc-Ala-OH-3-13C. Uses: Peptide synthesis. Additional or Alternative Names: N-(9-Fluorenylmethoxycarbonyl)-L-alanine-3-13C, L-Alanine-3-13C, N-Fmoc. Product Category: Amino Acids. CAS No. 201489-21-6. Molecular formula: 13CH3CH(NH-Fmoc)CO2H. Mole weight: 312.32. Canonical SMILES: [13CH3][C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O. Product ID: ACM201489216-3. Alfa Chemistry ISO 9001:2015 Certified. Categories: Fmoc-Ala-OH (3-13C).
This pseudoproline dipeptide is undoubtedly the most effective and simplest to use tool for overcoming aggregation and enhancing peptide quality in Fmoc SPPS for peptide containing the Ala-Ser dipeptide motif. It consists of a dipeptide in which the serine residue has been reversibly protected as a structure-breaking proline-like TFA-labile oxazolidine. The reason the pseudoproline residue is introduced as a dipeptide is because it avoids the need to acylate the hindered oxazolidine nitrogen. This has the added advantage of extending the peptide chain by two residues in one step. The serine residue is regenerated during the normal TFA-mediated cleavage reaction. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Ala-Ser(psiMe,Mepro)-OH. Product Category: Amino Acids. CAS No. 252554-78-2. Mole weight: 438.47. Product ID: ACM252554782-1. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Ala-Ser[Psi(Me,Me)Pro]-OH 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 252554-78-2. Pack Sizes: 1g, 5g, 10g. US Biological Life Sciences.
Worldwide
Fmoc-Ala-Ser(yMe,Mepro)-OH
Fmoc-Ala-Ser(yMe,Mepro)-OH. Group: Biochemicals. Grades: Highly Purified. CAS No. 252554-78-2. Pack Sizes: 500mg, 1g, 2g, 5g. US Biological Life Sciences.
Worldwide
Fmoc-Ala-Thr(psiMe,Mepro)-OH
This pseudoproline dipeptide is undoubtedly the most effective and simplest to use tool for overcoming aggregation and enhancing peptide quality in Fmoc SPPS for peptide containing the Ala-Thr dipeptide motif. It consists of a dipeptide in which the threonine residue has been reversibly protected as a structure-breaking proline-like TFA-labile oxazolidine. The reason the pseudoproline residue is introduced as a dipeptide is because it avoids the need to acylate the hindered oxazolidine nitrogen. This has the added advantage of extending the peptide chain by two residues in one step. The threonine residue is regenerated during the normal TFA-mediated cleavage reaction. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Ala-Thr(psiMe,Mepro)-OH. Product Category: Amino Acids. CAS No. 252554-79-3. Mole weight: 452.5. Product ID: ACM252554793-1. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Ala-Thr[Psi(Me,Me)Pro]-OH
Used in the solid phase synthesis of peptides which are difficult to make. Synonyms: Fmoc-Ala-Thr[y(Me,Me)Pro]-OH; (4S,5R)-3-(Fmoc-Ala)-2,2,5-trimethyl-oxazolidine-4-carboxylic acid; Fmoc-Ala-Thr(psi(Me,Me))-OH; Fmoc-Ala-Thr(y(Me,Me))-OH; (4S,5R)-3-[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoyl]-2,2,5-trimethyl-1,3-oxazolidine-4-carboxylic acid. Grades: 95-105% (Assay by titration). CAS No. 252554-79-3. Molecular formula: C25H28N2O6. Mole weight: 452.51.
Fmoc-Ala-Thr[Psi(Me,Me)Pro]-OH 99+% (HPLC)
Fmoc-Ala-Thr[Psi(Me,Me)Pro]-OH 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 252554-79-3. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
Fmoc-Ala-Thr(y(Me,Me))-OH
Fmoc-Ala-Thr(y(Me,Me))-OH. Group: Biochemicals. Alternative Names: (4S,5R)-3-(Fmoc-Ala)-2,2,5-trimethyl-oxazolidine-4-carboxylic acid. Grades: Highly Purified. CAS No. 252554-79-3. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. US Biological Life Sciences.
Fmoc-α-Me-Leu-OH is a leucine derivative with an Fmoc protecting group, which can be used to synthesize peptides with oxytocin receptor agonist activity [1]. Uses: Scientific research. Group: Peptides. CAS No. 312624-65-0. Pack Sizes: 250 mg; 1 g; 5 g; 10 g. Product ID: HY-W048739.
Fmoc-alpha-Me-L-Leucine
Fmoc-alpha-Me-L-Leucine. Group: Biochemicals. Alternative Names: Fmoc-a-Me-L-Leu-OH. Grades: Highly Purified. CAS No. 312624-65-0. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. US Biological Life Sciences.