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| Product | Description | |
|---|---|---|
| Futibatinib | Futibatinib (TAS-120) is an orally bioavailable, highly selective, and irreversible FGFR inhibitor, with IC 50 s of 3.9, 1.3, 1.6, and 8.3 nM for FGFR 1-4, respectively. Futibatinib inhibits mutant and wild-type FGFR2 with similar IC 50 s (wild-type FGFR2=0.9?nM; V5651=1-3?nM; N550H=3.6?nM; E566G=2.4?nM) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAS-120. CAS No. 1448169-71-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100818. |  |
| Futoquinol | Futoquinol is a neolignan isolated from the dried aerial parts of Piper kadsura (Piperaceae). Futoquinol potently inhibits NO production in microglia cells. Futoquinol has anti-neuroinflammatory activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 28178-92-9. Pack Sizes: 1 mg. Product ID: HY-N3915. | |
| Futuximab | Futuximab is a chimeric monoclonal antibody targeting non-overlapping epitopes on EGFR. Futuximab has antineoplastic activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1310460-85-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99628. | |
| Fuzapladib | Fuzapladib (IS-741), an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IS-741. CAS No. 141283-87-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19151. | |
| Fuzapladib sodium | Fuzapladib (IS-741) sodium, an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib sodium is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib sodium exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IS-741 sodium. CAS No. 141284-73-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19151A. | |
| Fuziline | Fuziline. Group: Biochemicals. Alternative Names: 15-Hydroxyneoline; 15-Epinagarine; Senbusine C. Grades: Plant Grade. CAS No. 80665-72-1. Pack Sizes: 20mg. Molecular Formula: C24H39NO7, Molecular Weight: 453.569. US Biological Life Sciences. |  Worldwide |
| Fuziline | Fuziline is extracted from the roots of Aconitum carmichaeli Debx. Synonyms: Aconitane-1,8,14,15-tetrol, 20-ethyl-6,16-dimethoxy-4-(methoxymethyl)- , (1alpha, 6alpha, 14alpha, 15alpha, 16beta)-; 15-Epinagarine; 15-Hydroxyneoline; Senbusine C. Grades: >98%. CAS No. 80665-72-1. Molecular formula: C24H39NO7. Mole weight: 453.6. |  |
| Fuzuloparib | Fuzuloparib is a poly (ADP-ribose) polymerase (PARP) inhibitor potentially for the treatment of solid tumours. Synonyms: 4-({4-fluoro-3-[2-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[1,5-a]pyrazine-7(8H)-carbonyl]phenyl}methyl)phthalazin-1(2H)-one; 1(2H)-Phthalazinone, 4-[[3-[[5,6-dihydro-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrazin-7(8H)-yl]carbonyl]-4-fluorophenyl]methyl]-; Fuzuopali; SHR-3162; Fuzuloparibum. Grades: ≥98%. CAS No. 1358715-18-0. Molecular formula: C22H16F4N6O2. Mole weight: 472.40. | |
| FW1256 | Exogenous H2S, as we know, has anti-inflammatory effects both in macrophages and in animal models. FW1256 is a slow release H2S dononr and it is much more potent in cells. FW1256 may be useful for studies of H2S in biology and could also have future therapeutic value in inflammatory conditions. Uses: Anti-inflammation. Synonyms: FW1256; FW-1256; FW 1256. 2-phenyl-3H-benzo[d][1,3,2]oxazaphosphole 2-sulfide. Grades: 98%. CAS No. 117089-08-4. Molecular formula: C12H10NOPS. Mole weight: 247.25. | |
| FX1 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| FX1 | FX1 is a potent and specific BCL6 inhibitor, with an IC 50 of around 35 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1426138-42-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-102027. | |
| FX1 | FX1 is a selective inhibitor of B cell lymphoma 6 (BCL6) (IC50 = 35 μM in reporter assays), which can disrupt formation of the BCL6 repression complex, reactivate BCL6 target genes and mimick the phenotype of mice engineered to express BCL6 with corepressor binding site mutations. FX1 also inhibits ABC-DLBCL cells. Synonyms: FX1; FX-1; FX 1. SCHEMBL16323186; CHEBI:133537; AKOS015865677; CS-7688; HY-102027; 3-[(5Z)-5-(5-chloro-2-oxo-1H-indol-3-ylidene)-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]propanoic acid. Grades: 99.75 %. CAS No. 1426138-42-2. Molecular formula: C14H9ClN2O4S2. Mole weight: 368.82. | |
| FX-909 | FX-909 is a covalent peroxisome proliferator-activated receptor gamma ( PPARG ) inverse agonist. FX-909 can be used for the research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2924573-90-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153344. | |
| FXIIIa-IN-1 sodium | C.I.Reactive Black 5 (Technical Grade) is a biological molecule. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Reactive Black 5. CAS No. 17095-24-8. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-W783421. | |
| FY26 (complex) | This active moleculr is a Os(II) anticancer drug candidate. It can generate reactive oxygen species and disrupt the redox balance in cancer cells. Using FY26 and nontoxic doses of L-BSO together allows the potentiation of its anticancer activity and inpartantly, it improves the selectivity for cancer cells versus normal fibroblasts. FY26 can shut down a cancer cell by exploiting weaknesses inherent in their energy generation. Uses: Anti-cancer. Synonyms: FY26; FY-26; FY 26. Osmium(1+)?, [N, ?N-dimethyl-4-[2-(2-pyridinyl-κN)?diazenyl-κN1]?benzenamine]?iodo[(1, ?2, ?3, ?4, ?5, ?6-η)?-1-methyl-4-(1-methylethyl)?benzene]?-, hexafluorophosphate(?1-) (1:1). Grades: 98%. CAS No. 1255143-82-8. Molecular formula: C23H28F6IN4OsP. Mole weight: 822.60. | |
| FYN A, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| FYN A active human | recombinant, expressed in baculovirus infected Sf9 cells, ?60% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| FzM1 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| FzM1 | FzM1 is a negative allosteric modulator (NAM) of Frizzled receptor FZD4. FzM1 reduces WNT5A-dependent WNT responsive element (WRE) activity (log EC 50inh =-6.2). FzM1 binds to an allosteric binding site located in intracellular loop 3 (ICL3) of FZD4 and alters the conformation of the receptor, ultimately inhibiting the WNT/β-catenin cascade [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1680196-54-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116553. | |
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