American Chemical Suppliers

A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.

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Product
FPL 64176 FPL 64176. Group: Biochemicals. Grades: Purified. CAS No. 120934-96-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
FPQIrpic FPQIrpic. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Iridium(III) bis(2-(2,4-difluorophenyl)quinoline)picolinate. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1621179-34-7. Molecular formula: C36H20F4IrN3O2. Mole weight: 795.11 g/mol. Product ID: ACM1621179347. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
FPR A14 FPR A14. Group: Biochemicals. Grades: Purified. CAS No. 329691-12-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
FPR A14 FPR A14 is a formyl peptide receptor (FPR) agonist that potently activates neutrophils in vitro (EC50 = 42 and 630 nM for neutrophil chemotaxis and Ca2+ mobilization, respectively). Synonyms: AG 14; AG14; AG-14; 1,3-Benzodioxolane-5-carboxylic acid 4'-benzyloxy-3'-methoxybenzylidene hydrazide. Grades: ≥99% by HPLC. CAS No. 329691-12-5. Molecular formula: C23H20N2O5. Mole weight: 404.42. BOC Sciences 9
FPS-ZM1 FPS-ZM1 is a high-affinity RAGE inhibitor with a K i of 25 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 945714-67-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-19370. MedChemExpress MCE
FPS-ZM1 FPS-ZM1 is a high-affinity RAGE-specific blocker that inhibits amyloid-β binding to the V domain of RAGE with Ki of 25 ± 5 nM in RAGE-transfected CHO cells. It binds exclusively to RAGE and inhibits β-secretase activity and Aβ production. It also suppresses microglia activation and the neuroinflammatory response in brain. It penetrates the blood-brain barrier and binds to RAGE, thus reducing the protein levels of various cytokines. It inhibits RAGE-mediated influx of circulating Aβ40 and Aβ42 into the brain. It is not toxic to mice and can easily cross the blood-brain barrier in vivo. It might be a novel therapeutic agent to treat AD patients. Uses: Fps-zm1 might be a novel therapeutic agent to treat ad patients. Synonyms: FPS-ZM1; FPS ZM1; FPSZM1; FPS-ZM 1; FPS ZM-1; FPSZM 1; N-benzyl-4-chloro-N-cyclohexylbenzaMide;4-Chloro-N-cyclohexyl-N-(phenylmethyl)benzamide. Grades: >98 %. CAS No. 945714-67-0. Molecular formula: C20H22ClNO. Mole weight: 327.85. BOC Sciences 10
FPT FPT, a 2-Aminotetralin, is an efficacious partial agonist at 5-HT 1A R , a full agonist at 5-HT 1B R and 5-HT 1D R with EC 50 s of 39.3 nM, 1.2 nM, 0.5 nM, respectively. FPT is a weak agonist at 5-HT 7 R. FPT shows in vivo efficacy as an antiepileptic in Fmr1 knockout mice and has anxiolytic-like and prosocial effects in Fmr1 knockout mice and other mouse models [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2048491-06-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-160887. MedChemExpress MCE
FP-TZTP FP-TZTP. Group: Biochemicals. Alternative Names: 3-[4-[(3-Fluoropropyl)thio]-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridine. Grades: Highly Purified. CAS No. 424829-90-3. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C11H16FN3S2. US Biological Life Sciences. USBiological 7
Worldwide
FQI1 FQI1 is a Late SV40 Factor ( LSF ) inhibitor. FQI1 inhibits cell proliferation, with IC 50 s of 3, 0.79, 6.3 μM for NIH/3T3, HeLa, A549 cells. FQI1 can be used for cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 599151-35-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-124429. MedChemExpress MCE
FQI 1 FQI 1 is a cell-permeable and reversible inhibitor of α-globin transcription factor CP2 (LSF; IC50 = 2.1 μM) and an antiproliferative. FQI 1 induces apoptosis in LSF-overexpressing cells, including Hepatocellular carcinoma (HCC cells). FQI 1 acts via inhibiting LSF-DNA binding. Uses: Antiproliferative. Synonyms: FQI 1; FQI1; FQI-1; 8-(2-ethoxyphenyl)-7,8-dihydro[1,3]dioxolo[4,5-g]quinolin-6(5H)-one; 8-(2-Ethoxy-phenyl)-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]quinolin-6-one. Grades: 99%. CAS No. 599151-35-6. Molecular formula: C18H17NO4. Mole weight: 311.33. BOC Sciences 9
FR054 FR054 is an inhibitor of the Hexosamine Biosynthetic Pathway (HBP) enzyme PGM3, with a remarkable anti-breast cancer effect. FR054 induces in different breast cancer cells a dramatic decrease in cell proliferation and survival. In particular, in a model of Triple Negative Breast Cancer (TNBC) cells, MDA-MB-231, these effects are correlated to FR054-dependent reduction of both N- and O-glycosylation level that cause also a strong reduction of cancer cell adhesion and migration. Note: The correct structure for FR054 is CAS#35954-65-5 which is the 6S-isomer. Some vendors are selling wrong structure for FAR054 (the incorrect structure has CAS#10378-06-0, which is the 6R-isomer). Note this product is being supplied as ethanol solution at 100mg/mL. Uses: Designed for use in research and industrial production. Additional or Alternative Names: FR054; FR-054; FR 054. Product Category: Inhibitors. Appearance: Viscouse waxy semi-solid. CAS No. 35954-65-5. Molecular formula: C14H19NO8. Mole weight: 329.31. Purity: >98%. IUPACName: 5H-Pyrano[3,2-d]oxazole-6,7-diol, 5-[(acetyloxy)methyl]-3a,6,7,7a-tetrahydro-2-methyl-, diacetate (ester), (3aR,5R,6S,7R,7aR)-. Canonical SMILES: CC1=N[C@@]([C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](COC(C)=O)O2)([H])[C@@]2([H])O1. Product ID: ACM35954655-1. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
FR 110302 This active molecular is a potent 5-lipoxygenase inhibitor which was originated by Fujisawa company for treating asthma. No-Development was reported for asthma in Japan. Synonyms: FR 110302; FR110302; FR-110302. 2,2-dibutyl-1,2,3,4-tetrahydro-5-(2-quinolinylmethoxy)-1-Naphthalenol. Grades: 98%. CAS No. 119256-94-9. Molecular formula: C28H35NO2. Mole weight: 417.58. BOC Sciences 10
FR 113680 FR 113680 is a novel tripeptide substance P antagonist with NK1 receptor selectivity originated by Fujisawa for the treatment of Asthma. But no development are reported yet. Uses: Asthma. Synonyms: FR 113680; FR113680; FR-113680; Ac-Thr-trp(cho)-phe-N-mebzl. Ac-Thr-trp(cho)-phe-N-mebzl;N-acetyl-L-threonyl-1-formyl-D-tryptophyl-N-methyl-N-(phenylmethyl)-L-Phenylalaninamide. Grades: 98%. CAS No. 126088-92-4. Molecular formula: C35H39N5O6. Mole weight: 625.72. BOC Sciences 9
FR 121196 FR 121196 is a potential antidementia drug originated by Fujisawa. Mechanism of Action is not undefined. FR 121196 can ameliorate the impaired memory of rat in the Morris water maze. No development was reported for Cognition disorders in Japan. Uses: Cognition disorders. Synonyms: FR 121196; FR 121196; FR 121196. N-(4-acetylpiperazin-1-yl)-4-fluorobenzenesulfonamide. Grades: 98%. CAS No. 133920-65-7. Molecular formula: C12H16FN3O3S. Mole weight: 301.34. BOC Sciences 9
FR122047 FR122047 (hydrochloride) is a selective and oral active inhibitor of COX-1 with an IC 50 of 28 nM. FR122047 hydrochloride has antiplatelet, analgesic and anti-inflammatory effects in vivo [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 130717-51-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103386. MedChemExpress MCE
FR 122047 hydrochloride FR 122047 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 130717-51-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
FR 122047 hydrochloride FR-122047 is a selective cyclooxygenase-1 (COX-1) inhibitor with IC50 values is 0.028μM for COX-1 and 65 μM for COX-2. FR-122047 displays 2300 fold greater selectivity towards inhibition of COX-1 over COX-2. It shows analgesic, anti-platelet and anti-inflammatory properties. No development was reported for the treatment of Pain, Rheumatoid arthritis and Thrombosis. Uses: Pain; rheumatoid arthritis; thrombosis. Synonyms: FR 122047 hydrochloride;1-[[4,5-bis-(4-Methoxyphenyl)-2-thiazolyl]carbonyl]-4-methylpiperazine hydrochloride. Grades: >98 %. CAS No. 130717-51-0. Molecular formula: C23H25N3O3S.HCl. Mole weight: 459.99. BOC Sciences 10
FR122047 hydrochloride hydrate FR122047 is a selective inhibitor of COX-1 with an IC50 value of 0.028 μM. Synonyms: 1-[[4,5-bis(4-methoxyphenyl)-2-thiazolyl]carbonyl]-4-methyl-piperazine, monohydrochloride, monohydrate. Grades: ≥98%. Molecular formula: C23H25N3O3S·HCl·H2O. Mole weight: 478. BOC Sciences 10
FR 139317 FR 139317 is a selective Endothelin A receptor antagonist originated by Fujisawa. (Ki values are 1 nM and 7.3 μM at ETA and ETB subtypes respectively). No development was reported for the treatment of Cerebrovascular disorders, Coronary disorders, Diabetic nephropathies, Heart failure, Hypertension, Ischaemic heart disorders, Myocardial infarction and Renal failure. Uses: Cerebrovascular disorders; coronary disorders; diabetic nephropathies; heart failure; hypertension; ischaemic heart disorders; myocardial infarction; renal failure. Synonyms: FR 139317; FR139317; FR139317; PD 147953; PD147953; PD-147953; 2-((1-(Hexahydro-1H-azepinyl)carbonyl)amino-4-methylpentanoyl)-3-(-(1-methyl-1H-indolyl)propionyl)amino-3-(2-pyridyl)propionic acid. Grades: 98 %. CAS No. 142375-60-8. Molecular formula: C33H44N6O5. Mole weight: 604.75. BOC Sciences 10
FR 139317 FR 139317. Group: Biochemicals. Grades: Purified. CAS No. 142375-60-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
FR-167356 FR-167356, a benzofuran derivative, has been found to be an acuolar ATPase inhibitor and could probablye be useful in studies of some lytic bone diseases. Synonyms: FR-167356; FR167356; FR 167356; UNII-XF02B1HC8R. DSSTox_CID_28148; DSSTox_RID_82712; 2,6-dichloro-N-[3-(2-hydroxypropan-2-yl)-2-methyl-1-benzofuran-7-yl]benzamide. Grades: 98%. CAS No. 174185-16-1. Molecular formula: C19H17Cl2NO3. Mole weight: 378.25. BOC Sciences 11
FR-167653 FR-167653 is a p38 mitogen-activated protein kinase inhibitor, which suppresses the development of endometriosis in a murine model. FR-167653 meliorates murine bleomycin-induced pulmonary fibrosis. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: FR-167653; FR 167653; FR167653. CAS No. 158876-66-5. Molecular formula: C24H20FN5O6S. Mole weight: 525.51. BOC Sciences 11
FR-167653 Free base FR-167653, a pyrazolo?triazin derivative, has been found to be a cytokine inhibitor as well as P38 mitogen-activated protein kinase inhibitor and was once studied as an anticoagulant. Synonyms: FR167653; FR-167653; FR 167653; 1,?2-Ethanedione, 1-[7-(4-fluorophenyl)?-3,?4-dihydro-8-(4-pyridinyl)?pyrazolo[5,?1-c]?[1,?2,?4]?triazin-2(1H)?-yl]?-2-phenyl-. Grades: 98%. CAS No. 158876-65-4. Molecular formula: C24H18FN5O2. Mole weight: 427.43. BOC Sciences 10
FR-168888 FR-168888, a guanidine compound, has been found to be a sodium hydrogen antiporter inhibitor that was once studied in myocardial ischaemia therapy. Synonyms: FR-168888; FR 168888; FR168888; Benzamide, N-(aminoiminomethyl)-3-(hydroxymethyl)-5-(1H-pyrrol-1-yl)-, methanesulfonate (1:1). Grades: 98%. CAS No. 168620-46-0. Molecular formula: C14H18N4O5S. Mole weight: 354.38. BOC Sciences 9
FR-168888 Free Base The free base of FR-168888, a guanidine compound, has been found to be a sodium hydrogen antiporter inhibitor that was once studied in myocardial ischaemia therapy. Synonyms: FR-168888 free base; FR 168888 free base; FR168888 free base; SCHEMBL1388039; SCHEMBL8300855; Benzamide, N-(aminoiminomethyl)-3-(hydroxymethyl)-5-(1H-pyrrol-1-yl)-. Grades: 98%. CAS No. 168620-45-9. Molecular formula: C13H14N4O2. Mole weight: 258.28. BOC Sciences 9
FR 171113 FR 171113 is a protease-activated receptor 1 (PAR1) antagonist displaying significant antiplatelet activity in vitro. It inhibits thrombin TRAP-6-induced platelet aggregation (IC50 = 2.5 μM) with no effect on coagulation time. Synonyms: FR 171113; FR171113; FR-171113; 2-[3-(4-Chlorophenyl)-2-[(2,4-dichlorobenzoyl)imino]-4-oxo-5-thiazolidinylidene]-acetic acid methyl ester. Grades: ≥98% by HPLC. CAS No. 173904-50-2. Molecular formula: C19H11Cl3N2O4S. Mole weight: 469.73. BOC Sciences 10
FR 171113 FR 171113. Group: Biochemicals. Grades: Purified. CAS No. 173904-50-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
FR 179642 FR 179642 is an impurity of Micafungin, which is an antifungal agent. Synonyms: FR-179642; FR179642; Pneumocandin M1; 1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0; 1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]-4-[(S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0; CMICA; FR 133303. Grades: ≥95%. CAS No. 168110-44-9. Molecular formula: C35H52N8O20S. Mole weight: 936.89. BOC Sciences
FR-179642 FR-179642 is a cyclic peptide and an important intermediate in producing micafungin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: FR-133303; FR 133303; FR133303; FR-179642; FR 179642; FR179642; Micafungin FR-179642 impurity; Pneumocandin M1. Product Category: Others. Appearance: Solid powder. CAS No. 168110-44-9. Molecular formula: C35H52N8O20S. Mole weight: 936.9. Purity: >98%. IUPACName: 5-((1S,2S)-2-((2R,6S,9S,11R,12R,14aS,15S,16S,20S,23S,25aS)-9-amino-20-((R)-3-amino-1-hydroxy-3-oxopropyl)-2,11,12,15-tetrahydroxy-6-((R)-1-hydroxyethyl)-16-methyl-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-23-yl)-1,2-dihydroxyethyl)-2-hydroxyphenyl hydrogen sulfate. Canonical SMILES: C[C@@H](O)[C@@H]1NC(=O)[C@@H](N)C[C@@H](O)[C@@H](O)NC(=O)[C@@H]2[C@@H](O)[C@@H](C)CN2C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]3C[C@@H](O)CN3C1=O)[C@H](O)[C@@H](O)c4ccc(O)c(OS(=O)(=O)O)c4)[C@H](O)CC(=O)N. Product ID: ACM168110449. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
FR-179642 FR-179642. Group: Biochemicals. Grades: Highly Purified. CAS No. 168110-44-9. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C35H52N8O20S. US Biological Life Sciences. USBiological 7
Worldwide
FR180204 FR180204 is a novel and selective inhibitor of extracellular signal-regulated kinase (ERK), which may be a potential new therapy for rheumatoid arthritis.FR180204 showed activity to inhibit ERKs (IC50 values are 0.14 and 0.31 μM for ERK2 and ERK1 respectively). Synonyms: FR180204; FR-180204; FR 180204. Grades: 0.98. CAS No. 865362-74-9. Molecular formula: C18H13N7. Mole weight: 327.351. BOC Sciences 10
FR 180204 FR 180204 is an ATP-competitive and selective ERK inhibitor. FR 180204 inhibits ERK1 and ERK2 with IC 50 s of 0.51 μM ( K i =0.31 μM) and 0.33 μM ( K i =0.14 μM), respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 865362-74-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12275. MedChemExpress MCE
FR 180204 FR 180204. Group: Biochemicals. Grades: Purified. CAS No. 865362-74-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
FR-181074 FR-181074 may be a bio-active chemical to treat Male Sexual Dysfunction. Synonyms: 1-[(2-chlorophenyl)methyl]-3-(2-methylpropanoyl)-2-propylindole-6-carboxamide; FR-181074; FR181074; FR 181074; UNII-D3C5RV093V. Grades: >98%. CAS No. 184147-65-7. Molecular formula: C23H25ClN2O2. Mole weight: 396.91. BOC Sciences 9
FR-181157 FR-181157, an oxazol derivative, has been found to be a prostaglandin mimetic and could have potential biological activities as a IP receptor agonist. Synonyms: FR-181157; FR 181157; FR181157; FR-181157 Free Base. (S)-FR-181157; SCHEMBL8057380; sodium;2-[3-[[(1S)-2-(4,5-diphenyl-1,3-oxazol-2-yl)cyclohex-2-en-1-yl]methyl]phenoxy]acetate. Grades: 98%. CAS No. 171046-15-4. Molecular formula: C30H26NNaO4. Mole weight: 487.52. BOC Sciences 9
FR-181157 Free base FR-181157 is an orally active prostacyclin mimetic that shows high potency and agonist efficacy at the IP receptor. Synonyms: sodium;2-[3-[[(1S)-2-(4,5-diphenyl-1,3-oxazol-2-yl)cyclohex-2-en-1-yl]methyl]phenoxy]acetate; FR 181157; FR181157; 200433-03-0 (FR-181157 Free Base). Grades: >98%. CAS No. 200433-03-0. Molecular formula: C30H26NNaO4. Mole weight: 487.52. BOC Sciences 10
FR-181877 FR-181877, an oxopyridazin derivative, has been found to be a nonprostanoid PGI2 agonist and could restrain the aggregation of human platelets induced by ADP. IC50: 0.081μM. Synonyms: FR-181877; FR 181877; FR181877. (-)-FR-181877; 2-[[(6S)-6-[(3-benzhydryl-6-oxopyridazin-1-yl)methyl]-5,6,7,8-tetrahydronaphthalen-1-yl]oxy]acetic acid. Grades: 98%. CAS No. 172936-99-1. Molecular formula: C30H28N2O4. Mole weight: 480.56. BOC Sciences 9
FR-182024 FR-182024, an azabicyclo derivative, has been found to have potential activity as an anti-Helicobacter pylori agent and was once stuied against helicobacter infections. Synonyms: FR-182024; FR 182024; FR182024. 9031SV3FWE; (6R,7R)-3-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]-8-oxo-7-[(2-phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. Grades: 98%. CAS No. 179034-83-4. Molecular formula: C18H16N4O4S3. Mole weight: 448.53. BOC Sciences 9
FR-182877 FR-182877 is produced by the strain of Streptomyces sp. No. 9885. It has a strong effect on rat ascites and solid tumors in vivo, and has no antibacterial activity. Molecular formula: C24H32O5. Mole weight: 400.51. BOC Sciences 5
FR-182980 FR-182980, a pyridine derivative, has been found to be a sterol O-acyltransferase inhibitor and was once studied in hypercholesterolaemia. Synonyms: FR-182980; FR182980; FR 182980; 1-cycloheptyl-1-[[4-(4-fluorophenoxy)phenyl]methyl]-3-[6-methyl-2,4-bis(methylsulfanyl)pyridin-3-yl]urea. Grades: 98%. CAS No. 179054-51-4. Molecular formula: C29H34FN3O2S2. Mole weight: 539.73. BOC Sciences 9
FR-186054 FR-186054, a pyridine derivative, has been found to be a sterol O-acyltransferase inhibitor and was once studied in hyperlipidaemia. Synonyms: FR-186054; FR 186054; FR186054; 1-benzyl-3-[6-methyl-2,4-bis(methylsulfanyl)pyridin-3-yl]-1-[[3-(1H-pyrazol-5-yl)phenyl]methyl]urea. Grades: 98%. CAS No. 179053-90-8. Molecular formula: C26H27N5OS2. Mole weight: 489.66. BOC Sciences 9
FR-188582 FR-188582, with anti-inflammatory and ulcerogenic properties, is a highly selective inhibitor of COX-2 with IC50=0.017 microM. Synonyms: 3-chloro-5-(4-methylsulfonylphenyl)-1-phenylpyrazole; FR 188582; FR188582; FR-188582. Grades: >98%. CAS No. 189699-82-9. Molecular formula: C16H13ClN2O2S. Mole weight: 332.8. BOC Sciences 10
FR-190809 FR-190809 is a potent and orally efficacious ACAT inhibitor potentially for the treatment of Lipoprotein Disorders. Synonyms: 1-cycloheptyl-1-[[4-(4-fluorophenoxy)phenyl]methyl]-3-[6-methyl-2,4-bis(methylsulfonyl)pyridin-3-yl]urea; FR-190809; FR 190809; FR190809.N-cycloheptyl-N-(4-(4-fluorophenoxy)-benzyl)-N'-(2,4-bis(methylsulfonyl)-6-methylpyridin-3-yl)urea. Grades: >98%. CAS No. 215589-63-2. Molecular formula: C29H34FN3O6S2. Mole weight: 603.73. BOC Sciences 9
FR-191512 It is a polyphenolic compound with anti-influenza A virus effect. Synonyms: FR191512. Molecular formula: C38H38O16. Mole weight: 750.70. BOC Sciences 5
FR-193262 FR-193262 is a designed prostacyclin mimetic without PG skeleton which exhibits potent PGI2 agonistic activity with good selectivity for IP receptor and bioavailability. Synonyms: FR-193262; FR 193262; FR193262; sodium;2-[[(5R)-5-[(2R)-2-(4,5-diphenyl-1,3-oxazol-2-yl)pyrrolidin-1-yl]-5,6,7,8-tetrahydronaphthalen-1-yl]oxy]acetate; FR-193262; 187992-22-9(FR-193262); 314289-63-9 (FR-193262 Free Base). Grades: >98%. CAS No. 187992-22-9. Molecular formula: C31H29N2NaO4. Mole weight: 516.56. BOC Sciences 9
FR-193262 Free base A bio-active organic chemical. Uses: A bio-active organic chemical. Synonyms: FR-193262; FR 193262; FR193262; 2-[[(5R)-5-[(2R)-2-(4,5-diphenyl-1,3-oxazol-2-yl)pyrrolidin-1-yl]-5,6,7,8-tetrahydronaphthalen-1-yl]oxy]acetic acid. Grades: ≥98%. CAS No. 314289-63-9. Molecular formula: C31H30N2O4. Mole weight: 494.59. BOC Sciences 9
FR-193879 FR-193879, a cephem derivative, is an efficacious anti-Helicobacter pylori cephalosporin. Synonyms: (6R,7R)-3-[[4-(2-amino-2-oxoethyl)-1,3-thiazol-2-yl]sulfanyl]-8-oxo-7-[(2-phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; FR-193879; FR193879; FR 193879. Grades: >98%. CAS No. 194928-82-0. Molecular formula: C20H18N4O5S3. Mole weight: 490.58. BOC Sciences 10
FR-194921 FR-194921 is a potent, selective and orally active antagonist for central adenosine A1 receptors that displays high affinity and selectivity for the adenosine A1 receptor (Ki= 2.9 nM) and did not show species differences in binding affinity. Synonyms: 2-(1-methylpiperidin-4-yl)-6-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)pyridazin-3-one; FR-194921; FR 194921; FR194921; 2-(1-methyl-4-piperidinyl)-6-(2-phenylpyrazolo(1,5-a)pyridin-3-yl)-3(2H)-pyridazinone. Grades: >98%. CAS No. 202646-80-8. Molecular formula: C23H23N5O. Mole weight: 385.46. BOC Sciences 10
FR-198248 FR-198248, a new type of hydroxyl benzaldehyde compound, was isolated from the cultured broth of a fungal strain identified as Aspergillus terreus from morphological characteristics. FR-198248 exhibited anti-influenza virus activity in Madin-Darby canine kidney (MDCK) cells in vitro. Synonyms: fr198248; 1,3-Dihydro-4-methyl-1,5,6,7-isobenzofurantetraol. Grades: >98%. CAS No. 197316-54-4. Molecular formula: C9H10O5. Mole weight: 198.17. BOC Sciences 5
FR-202306 FR-202306 is a synthetic peptide deformylase (PDF) inhibitor. Uses: Peptide deformylase (pdf) inhibitor. Synonyms: FR-202306; FR 202306; FR202306. 3-methoxy-7-methyl-1,3-dihydro-2-benzofuran-4,5,6-triol. Grades: ≥98%. CAS No. 342785-41-5. Molecular formula: C10H12O5. Mole weight: 212.20. BOC Sciences 9
FR-217840 FR-217840 is a matrix metalloproteinase inhibitor. It can suppress joint destruction. FR217840 may have potential as a novel anti-rheumatic drug. Uses: Anti-rheumatic agent. Synonyms: FR-217840; FR217840; FR 217840. (2S)-1-((5-(4-fluorophenyl)-2-thienyl)sulfonyl)-N-hydroxy-4-(methylsulfonyl)-2-Piperazinecarboxamide. Grades: 98%. CAS No. 848444-16-6. Molecular formula: C16H18FN3O6S3. Mole weight: 463.52. BOC Sciences 9
FR-218944 FR-218944 is a vasopressin antagonist compound. Synonyms: methanesulfonic acid;2-methoxy-N-(2-methyl-1H-benzimidazol-4-yl)-4-(2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)benzamide; FR-218944; FR 218944; FR218944. Grades: >98%. CAS No. 233264-02-3. Molecular formula: C28H30N4O6S. Mole weight: 550.63. BOC Sciences 9
FR-221647 FR-221647 is a non-nucleoside adenosine deaminase inhibitor. Synonyms: 1-(1-hydroxy-4-phenylbutan-2-yl)imidazole-4-carboxamide; FR-221647; FR 221647; FR221647. Grades: >98%. CAS No. 256461-28-6. Molecular formula: C14H17N3O2. Mole weight: 259.3. BOC Sciences 10
FR225659 FR225659 is originally isolated from Helicomyces sp. No. 19353. It can suppress the gluconeogenesis induced by Glucagon in Primary hepatocytes of rats. Molecular formula: C36H42ClN7O8. Mole weight: 736.21. BOC Sciences 5
FR-229934 FR-229934 is a Type 5 cyclic nucleotide phosphodiesterase inhibitor. In Feb 2008, preclinical for Erectile dysfunction in Japan was discontinued. Uses: Erectile dysfunction. Synonyms: FR-229934; FR229934; FR 229934. 1-((3,4-dichlorophenyl)methyl)-2-methyl-N-(pentylsulfonyl)-1H-Benzimidazole-6-carboxamide. Grades: 98%. CAS No. 799841-02-4. Molecular formula: C21H23Cl2N3O3S. Mole weight: 468.40. BOC Sciences 10
FR-234938 FR-234938, with anti-inflammatory property, is a non-nucleoside recombinant human adenosine deaminase enzyme inhibitor. Synonyms: 1-[(3R,4S)-4-hydroxy-1-naphthalen-1-ylpentan-3-yl]imidazole-4-carboxamide; FR-234938; FR 234938; FR234938. Grades: >98%. CAS No. 256461-79-7. Molecular formula: C19H21N3O2. Mole weight: 323.39. BOC Sciences 10
FR-235222 FR-235222 is an immunosuppressive substance that inhibits mammalian histone deacetylase (HDAC). It is produced by the strain of Acremonium sp. No. 27082. Synonyms: FR 235222; FR235222. Molecular formula: C30H44N4O6. Mole weight: 556.69. BOC Sciences 5
FR236913 FR236913 is a compoundused in studying chronic lymphocytic leukemia (CLL) and other hematologic malignancies. This targeted therapy inhibits Bruton's tyrosine kinase (BTK) is a key enzyme in the B-cell receptor signaling pathway. By disrupting abnormal B-cell signaling, FR236913 helps control the progression of CLL. Synonyms: 1-[(2R)-4-{6-[(Benzylcarbamoyl)amino]-1H-indol-1-yl}-1-hydroxybutan-2-yl]-1H-imidazole-4-carboxamide. Molecular formula: C24H26N6O3. Mole weight: 446.5. BOC Sciences 10
FR 236924 FR 236924 is a selective PKCε activator with > 7-fold selectivity over other PKC isozymes. FR 236924 promotes glutamate release via presynaptic α7 nicotinic receptors on glutamatergic terminals in vitro and enhances cognition in vivo. It has the potential for the treatment of Alzheimer disease. Synonyms: FR 236924; FR236924; FR-236924; Dcp-LA; 2-[ (2-Pentylcyclopropyl) methyl]cyclopropaneoctanoic acid. Grades: ≥99% by HPLC. CAS No. 28399-31-7. Molecular formula: C20H36O2. Mole weight: 308.5. BOC Sciences 10
FR 236924 FR 236924. Group: Biochemicals. Grades: Purified. CAS No. 28399-31-7. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 5
Worldwide
FR-245 FR-245. Group: Polymers. CAS No. 25713-60-4. Product ID: 2,4,6-tris(2,4,6-tribromophenoxy)-1,3,5-triazine. Molecular formula: 1067.4g/mol. Mole weight: C21H6Br9N3O3. C1=C (C=C (C (=C1Br)OC2=NC (=NC (=N2)OC3=C (C=C (C=C3Br)Br)Br)OC4=C (C=C (C=C4Br)Br)Br)Br)Br. InChI=1S/C21H6Br9N3O3/c22-7-1-10 (25)16 (11 (26)2-7)34-19-31-20 (35-17-12 (27)3-8 (23)4-13 (17)28)33-21 (32-19)36-18-14 (29)5-9 (24)6-15 (18)30/h1-6H. BDFBPPCACYFGFA-UHFFFAOYSA-N. Alfa Chemistry Materials 4
FR252384 FR252384 is novel potent antagonists of human neuropeptide Y-Y5 receptor (IC50= 2.3 nM). Synonyms: FR252384; FR 252384; FR-252384; 9-methyl-2-pyridin-3-yl-3,4,5,6-tetrahydrobenzo[2,3]cyclohepta[2,4-b]imidazole; Benzo[3,4]cyclohept[1,2-d]imidazole, 1,4,5,6-tetrahydro-9-methyl-2-(3-pyridinyl)-. CAS No. 447405-11-0. Molecular formula: C18H17N3. Mole weight: 275.35. BOC Sciences 10
FR 252921 FR 252921 is produced by the strain of Pseudomonas fluorenscens No. 408813. It shows immunosuppressive effect in mice in vivo and in vitro, and has synergistic effect with FK-506. Molecular formula: C29H44N2O5. Mole weight: 500.67. BOC Sciences 5
FR-252922 FR-252922 is produced by the strain of Pseudomonas fluorenscens No. 408813. It shows immunosuppressive effect in mice in vivo and in vitro, and has synergistic effect with FK-506. Molecular formula: C31H48N2O5. Mole weight: 528.72. BOC Sciences 5
FR-29038 It is originally isolated from Nocardia uniformis subsp. tsuyamanensis. FR-29038 has anti-Bacillus, Escherichia, Klebsiella, Pseudomonas, Salmonella, Shigella and other family bacteria activities. Synonyms: Antibiotic FR 29038; BRN 3578863; O-{4-[1-Amino-2-({1-[carboxy(4-hydroxyphenyl)methyl]-2-oxoazetidin-3-yl}imino)-2-hydroxyethyl]phenyl}homoserine. CAS No. 59511-12-5. Molecular formula: C23H26N4O8. Mole weight: 486.47. BOC Sciences 5
FR295389 free base FR295389 free base is a new cephalosporin. It shows effective in vitro antibacterial activity against metallo-beta-lactamase (MBL)-producers. Uses: Fr295389 free base has effective antibacterial activity. Synonyms: FR-295389 free base; FR 295389 free base; FR295389 free base; (6R,7R)-3-[[7-[3-aminopropyl(carbamimidoyl)amino]-2,3-dihydroimidazo[1,2-b]pyrazol-5-yl]methyl]-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(2-carboxypropan-2-yloxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. Grades: >98 %. CAS No. 1019207-71-6. Molecular formula: C25H33N13O7S2. Mole weight: 691.74. BOC Sciences 9
FR295389 sulfuric acid FR295389 sulfuric acid is the sulfate form of FR295389, which is a new cephalosporin. It has effective in vitro antibacterial activity against metallo-beta-lactamase (MBL)-producers. Uses: Fr295389 sulfuric acid has effective antibacterial activity. Synonyms: FR-295389 sulfuric acid; FR 295389 sulfuric acid; FR295389 sulfuric acid; (6R,7R)-3-[[7-[3-aminopropyl(carbamimidoyl)amino]-2,3-dihydroimidazo[1,2-b]pyrazol-5-yl]methyl]-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(2-carboxypropan-2-yloxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sulfuric acid. Grades: >98 %. CAS No. 1019207-72-7. Molecular formula: C25H35N13O11S3. Mole weight: 789.81. BOC Sciences 9
FR 32863 FR 32863 is produced by the strain of Streptomyces lavendulae 8006. FR 32863 has anti-gram-positive and anti-gram-negative activities. Synonyms: Antibiotic FR 32863; Antibiotic FR 900136; BRN 2092108; FR-32863; (E)-(3-(Formylhydroxyamino)-1-propenyl)phosphonic acid. CAS No. 66508-88-1. Molecular formula: C4H8NO5P. Mole weight: 181.08. BOC Sciences 5
FR-33289 FR-33289 is produced by the strain of Streptomyces rubellomurinus subsp. indigoferus 24. FR-33289 has anti-gram-positive and anti-gram-negative activities. Synonyms: Antibiotic FR 33289; (R)-(3-(Acetylhydroxyamino)-2-hydroxypropyl)phosphonic acid. CAS No. 73240-15-0. Molecular formula: C5H12NO6P. Mole weight: 213.13. BOC Sciences 5
FR-62765 FR-62765, a derivative of WF-3681, is a novel aldose reductase inhibitor. It might be a useful drug for diabetic neuropathy. Uses: Fr-62765 might be a useful drug for diabetic neuropathy. Synonyms: FR 62765; FR-62765; FR62765. 2-Furanpropanoic acid, 2,5-dihydro-4-methoxy-5-oxo-3-phenyl-, ethyl ester;FR62765;2,5-Dihydro-4-methoxy-5-oxo-3-phenylfuran-2-propanoic acid ethyl ester;Ethyl 2,5-dihydro-4-methoxy-5-oxo-3-phenyl-2-furanpropanoate;Ethyl 3-(4-methoxy-5-oxo-3-phenyl-2H-furan-2-yl)propanoate. Grades: >98 %. CAS No. 105346-34-7. Molecular formula: C16H18O5. Mole weight: 290.31. BOC Sciences 10

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