A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Formylglycinamide Ribotide (FGAR), along with glutamine, takes part in the ATP-dependent synthesis of Formylglycinamidine Ribonucleotide (FGAM) in the fourth step of the purine biosynthetic pathway. Synonyms: 2-(Formylamino)-N-(5-O-phosphono-β-D-ribofuranosyl)acetamide; 2-Formamido-N-β-D-ribofuranosylacetamide 5'-(Dihydrogen phosphate); 5'-Phosphoribosyl-N-formylglycinamide; FGAR; Formylglycinamide Ribonucleotide; N-Formylglycinamide Ribonucleotide; Phosphoribosylformylglycinamide; α-N-Formylglycinamide Ribonucleotide. CAS No. 349-34-8. Molecular formula: C8H15N2O9P. Mole weight: 314.19.
Formylindole-dT CEP
Formylindole-dT CEP is a crucial compound in biomedicine used to enhance the efficiency of DNA sequencing. It serves as a modified nucleotide in the synthesis of oligonucleotides for research purposes. With its unique structure, Formylindole-dT CEP can be incorporated into DNA strands, allowing for precise identification and analysis of gene mutations associated with various diseases, including cancer and genetic disorders. Molecular formula: C59H70N7O11P. Mole weight: 1084.20.
Formyl-L-alanine
Formyl-L-alanine. Group: Biochemicals. Alternative Names: For-L-Ala-OH. Grades: Highly Purified. CAS No. 10512-86-4. Pack Sizes: 5g. US Biological Life Sciences.
Formyl-L-alanine methyl ester. Group: Biochemicals. Alternative Names: For-L-Ala-OMe. Grades: Highly Purified. CAS No. 32221-83-3. Pack Sizes: 2g, 5g. US Biological Life Sciences.
Worldwide
Formyl-L-alanine methyl ester 99+% (TLC)
Formyl-L-alanine methyl ester 99+% (TLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 32221-83-3. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
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Formyl-L-methionine
Formyl-L-methionine is a protein amino acid present in the organelles of bacteria and related eukaryotes. It is a derivative of the amino acid methionine, in which a formate is added to the amino group of the methionine. It plays a crucial role in protein biosynthesis in bacteria, Mitochondria and chloroplasts. But it is not used for protein biosynthesis in Eukaryotic Cytosol, in which only the nuclear genes are translated. It's also not used in ARCHAEA. In humans, it is recognized by the immune system as a foreign substance and stimulates the body to fight potential infections. Synonyms: For-L-Met-OH; N-Formyl-L-methionine; 2-formamido-4-methylsulfanylbutanoic acid; N-Formyl-L -Methionine; L-Methionine, N-formyl-; (S)-2-Formamido-4-(methylthio)butanoic acid. Grade: ≥ 98% (HPLC). CAS No. 4289-98-9. Molecular formula: C6H11NO3S. Mole weight: 177.22.
Formyl-L-methionine
Formyl-L-methionine. Group: Biochemicals. Alternative Names: For-L-Met-OH. Grades: Highly Purified. CAS No. 4289-98-9. Pack Sizes: 2g, 5g, 10g, 25g. US Biological Life Sciences.
Worldwide
Formyl-L-methionine 98+% (HPLC)
Formyl-L-methionine 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 4289-98-9. Pack Sizes: 1g, 5g, 25g, 100g. US Biological Life Sciences.
Formyl meldrum's acid. Group: Biochemicals. Alternative Names: 5-(Hydroxymethylene)-2,2-dimethyl-1,3-dioxane-4,6-dione; (Hydroxymethylene)-malonic acid. Grades: Highly Purified. CAS No. 15568-87-3. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C7H8O5. US Biological Life Sciences.
Worldwide
Formyl Meldrums Acid
Meldrum's Acid derivative. Antisecretory agent. Group: Biochemicals. Alternative Names: 5-(Hydroxymethylene)-2,2-dimethyl-1,3-dioxane-4,6-dione; (Hydroxymethylene)-malonic Acid. Grades: Highly Purified. CAS No. 15568-87-3. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
formylmethanofuran dehydrogenase
A molybdoprotein containing a pterin cofactor. Tungstate can substitute for molybdate. The enzyme catalyses a reversible reaction in methanogenic bacteria, and is involved in methanogenesis from CO2 as well as the oxidation of methyl-coenzyme M to CO2. Methyl viologen can act as acceptor. Also oxidizes N-furfurylformamide. Group: Enzymes. Synonyms: formylmethanofuran:(acceptor) oxidoreductase. Enzyme Commission Number: EC 1.2.99.5. CAS No. 119940-12-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1233; formylmethanofuran dehydrogenase; EC 1.2.99.5; 119940-12-4; formylmethanofuran:(acceptor) oxidoreductase. Cat No: EXWM-1233.
Methanofuran is a complex 4-substituted furfurylamine and is involved in the formation of methane from CO2 in Methanobacterium thermoautotrophicum. Group: Enzymes. Synonyms: formylmethanofuran-tetrahydromethanopterin formyltransferase; formylmethanofuran: tetrahydromethanopterin formyltransferase; N-formylmethanofuran(CHO-MFR):tetrahydromethanopterin(H4MPT) formyltransferase; FTR; formylmethanofuran:5,6,7,8-tetrahydromethanopterin N5-formyltransferase. Enzyme Commission Number: EC 2.3.1.101. CAS No. 105669-83-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2040; formylmethanofuran-tetrahydromethanopterin N-formyltransferase; EC 2.3.1.101; 105669-83-8; formylmethanofuran-tetrahydromethanopterin formyltransferase; formylmethanofuran: tetrahydromethanopterin formyltransferase; N-formylmethanofuran(CHO-MFR):tetrahydromethanopterin(H4MPT) formyltransferase; FTR; formylmethanofuran:5,6,7,8-tetrahydromethanopterin N5-formyltransferase. Cat No: EXWM-2040.
formylmethionine deformylase
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-formyl-L-methionine amidohydrolase. This enzyme participates in methionine metabolism and glyoxylate and dicarboxylate metabolism. Group: Enzymes. Enzyme Commission Number: EC 3.5.1.31. CAS No. 9032-86-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4421; formylmethionine deformylase; EC 3.5.1.31; 9032-86-4. Cat No: EXWM-4421.
Formylmethyl triphenylphosphonium chloride
25g Pack Size. Group: Building Blocks, Organics. Formula: C20H18ClOP. CAS No. 62942-43-2. Prepack ID 36702993-25g. Molecular Weight 340.78. See USA prepack pricing.
Formyl-Met-Leu-Phe-OH - CAS 59880-97-6
Chemotactic peptide for polymorphonuclear leukocytes. Group: Fluorescence/luminescence spectroscopy.
Formyl Peptide Receptor-Like 1 Antagonist, WRW?
The Formyl Peptide Receptor-Like 1 Antagonist, WRW? controls the biological activity of Formyl Peptide Receptor-Like 1. Group: Fluorescence/luminescence spectroscopy.
Formylpiperidine
Formylpiperidine. Group: Biochemicals. Alternative Names: 1-Formylpiperidine; Formylpiperidide; N-Carbaldehyde Piperidine; N-Formylpiperidine; N-Piperidinecarboxalde hyde; NFP; NSC 1066; NSC 404158; Piperidinoformamide. Grades: Highly Purified. CAS No. 2591-86-8. Pack Sizes: 50g. Molecular Formula: C6H11NO, Molecular Weight: 113.16. US Biological Life Sciences.
Worldwide
Formylpolystyrene
Resins for solid phase organic synthesis. Synonyms: Polystyrene aldehyde.
Formylpolystyrene
Formylpolystyrene. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g. US Biological Life Sciences.
Formyl polystyrene resin. Group: Polymers. Alternative Names: BENZALDEHYDE ON POLYSTYRENE. CAS No. 55279-75-9. Product ID: FORMYL POLYSTYRENE RESIN. Molecular formula: 105.11. Mole weight: C7H5O. 96%.
Formyl Polystyrene, Type1
This "polymeric benzaldehyde" reversibly binds e.g. amines or diols. Uses: The resin has been used to prepare 2,5-disubstituted tetrahydrofurans via electrophilic rearrangement of isoxazolines produced by the [3+2] addition of nitrile oxides to resin-bound alkenes and in the synthesis of new resins for chemical ligation and cyclization of unprotected peptides. Group: Formyl polystyrene resins. Pack Sizes: 5g, 25g, 100g.
Formyl Polystyrene, Type2
This "polymeric benzaldehyde" reversibly binds e.g. amines or diols. Uses: The resin has been used to prepare 2,5-disubstituted tetrahydrofurans via electrophilic rearrangement of isoxazolines produced by the [3+2] addition of nitrile oxides to resin-bound alkenes and in the synthesis of new resins for chemical ligation and cyclization of unprotected peptides. Group: Formyl polystyrene resins. Pack Sizes: 5g, 25g, 100g.
formyltetrahydrofolate deformylase
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is 10-formyltetrahydrofolate amidohydrolase. This enzyme participates in glyoxylate and dicarboxylate metabolism and one carbon pool by folate. Group: Enzymes. Enzyme Commission Number: EC 3.5.1.10. CAS No. 9025-8-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4378; formyltetrahydrofolate deformylase; EC 3.5.1.10; 9025-08-5. Cat No: EXWM-4378.
formyltetrahydrofolate dehydrogenase
This enzyme belongs to the family of oxidoreductases, to be specific those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 10-formyltetrahydrofolate:NADP+ oxidoreductase. Other names in common use include 10-formyl tetrahydrofolate:NADP oxidoreductase, 10-formyl-H2PtGlu:NADP oxidoreductase, 10-formyl-H4folate dehydrogenase, N10-formyltetrahydrofolate dehydrogenase, and 10-formyltetrahydrofolate dehydrogenase. This enzyme participates in one carbon pool by folate. Group: Enzymes. Synonyms: 10-formyl tetrahydrofolate:NADP oxidoreductase; 10-formyl-H2PtGlu:NADP oxidoreductase 10-formyl-H4folate dehydrogenase; N10-formyltetrahydrofolate dehydrogenase 10-formyltetrahydrofolate dehydrogenase. Enzyme Commission Number: EC 1.5.1.6. CAS No. 37256-25-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1533; formyltetrahydrofolate dehydrogenase; EC 1.5.1.6; 37256-25-0; 10-formyl tetrahydrofolate:NADP oxidoreductase; 10-formyl-H2PtGlu:NADP oxidoreductase 10-formyl-H4folate dehydrogenase; N10-formyltetrahydrofolate dehydrogenase 10-formyltetrahydrofolate dehydrogenase. Cat No: EXWM-1533.
Forodesine, also known as BCX-1777, is the hydrochloride salt of the synthetic high-affinity transition-state analogue forodesine. Forodesine binds preferentially to and inhibits purine nucleotide phosphorylase (PNP), resulting in the accumulation of deoxyguanosine triphosphate and the subsequent inhibition of the enzyme ribonucleoside diphosphate reductase and DNA synthesis. This agent selectively causes apoptosis in stimulated or malignant T-lymphocytes. A transition state analogue is a substrate designed to mimic the properties or the geometry of the transition state of reaction. Synonyms: Immucillin-H hydrochloride; Forodesine. Grade: 98%. CAS No. 209799-67-7. Molecular formula: C11H14N4O4. Mole weight: 266.25.
Forodesine
Forodesine (BCX-1777) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC 50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine is a potent human lymphocyte proliferation inhibitor. Forodesine could induce apoptosis in leukemic cells by increasing the dGTP levels [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BCX-1777; Immucillin-H. CAS No. 209799-67-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-16210.
FORODESINE
Forodesine (BCX-1777) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine is a potent human lymphocyte proliferation inhibitor. Forodesine could induce apoptosis in leukemic cells by increasing the dGTP levels. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: White to Yellow Solid. CAS No. 209799-67-7. Molecular formula: C11H14N4O4. Mole weight: 266.26. Purity: 0.95. Canonical SMILES: O=C1C(NC=C2[C@@H]3N[C@H](CO)[C@@H](O)[C@H]3O)=C2NC=N1. Product ID: ACM209799677. Alfa Chemistry ISO 9001:2015 Certified.
Forodesine hydrochloride
Forodesine hydrochloride is the hydrochloride salt of Forodesine. Forodesine, also called as BCX-1777 or Immucillin-H, is an orally bioavailable inhibior of mammalian purine nucleoside phosphorylase (PNP). Forodesine is undergoing a phase II trial to trea. Synonyms: 7-[(2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-2-yl]-1,5-dihydropyrrolo[3,2-d]pyrimidin-4-one; hydrochloride1-(9-deazahypoxanthin-9-yl)-1,4-dideoxy-1,4-iminoribitolBCX-1777; BCX1777BCX1777forodesineImmH cpdimmucillin Himmucillin-H. CAS No. 284490-13-7. Molecular formula: C11H15ClN4O4. Mole weight: 302.715.
Forodesine hydrochloride
Forodesine hydrochloride (BCX-1777 hydrochloride) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC 50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine hydrochloride is a potent human lymphocyte proliferation inhibitor. Forodesine hydrochloride could induce apoptosis in leukemic cells by increasing the dGTP levels [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BCX-1777 hydrochloride; Immucillin-H hydrochloride. CAS No. 284490-13-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-16209.
For-phe-gly-oh
For-phe-gly-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: FORMYL-L-PHENYLALANYL GLYCINE;FOR-PHE-GLY-OH;(S)-2-(2-amino-N-formyl-3-phenylpropanamido)acetic acid;REF DUPL: For-Phe-Gly-OH. Product Category: Heterocyclic Organic Compound. CAS No. 100135-64-6. Molecular formula: C12H14N2O4. Mole weight: 250.25. Product ID: ACM100135646. Alfa Chemistry ISO 9001:2015 Certified.
Forskolin
Forskolin is a naturally occurring diterpene that is produced by the Indian Coleus plant. It directly activates adenylyl cyclase through its catalytic subunit and is commonly used to raise levels of cAMP in a wide variety of intact cells and tissue preparations. Synonyms: Coleonol; HL 362; L 75-1362B; NSC 357088; NSC 375489; (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(Acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-Naphtho[2,1-b]pyran-1-one; (-)-Forskolin; Colforsin; ForsLean. Grade: ≥98%. CAS No. 66575-29-9. Molecular formula: C22H34O7. Mole weight: 410.50.
Forskolin
Forskolin (Coleonol) is a potent adenylate cyclase activator with an IC 50 of 41 nM and an EC 50 of 0.5 μM for type I adenylyl cyclase [1]. Forskolin is also an inducer of intracellular cAMP formation [2]. Forskolin induces differentiation of various cell types and activates pregnane X receptor (PXR) and FXR [3]. Forskolin exerts a inotropic effect on the heart, and has platelet antiaggregatory and antihypertensive actions. Forskolin also induces autophagy [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Coleonol; Colforsin; HL 362. CAS No. 66575-29-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-15371.
Forskolin is a diterpene isolated from Coleus forskohlii, possessing vasodilating and cardiostimulatory properties. Forskolin resensitizes cell receptors by activating the enzyme adenylyl cyclase and increasing the intracellular levels of cAMP. Alternative Names: 7BETA-ACETOXY-1ALPHA,6BETA,9ALPHA-TRIHYDROXY-8,13-EPOXY-LABD-14-EN-11-ONE;7BETA-ACETOXY-8,13-EPOXY-1ALPHA,6BETA,9ALPHA-TRIHYDROXY-LABD-14-EN-11-ONE;7BETA-ACETOXY-8,13-EPOXY-1ALPHA,6BETA,9ALPHA-TRIHYDROXY-LABD-14-ENE-11-ONE;[3R-(3A,4AB,5B,6B,6AA,10A,10AB,10BA)]-5-(ACETYLOXY)-3-ETHENYLDODECAHYDRO-6,10,10B-TRIHYDROXY-3,4A,7,7,10A-PENTAMETHYL-1H-NAPHTHO[2,1-B]PYRAN-1-ONE;10a-beta,10b-alpha))-10-alph;1-b)pyran-1-one,dodecahydro-5-(acetyloxy)-3-ethenyl-3,4a,7,7,10a-1h-naphtho(;pentamethyl-6,10,10b-trihydroxy-,(3r-(3-alpha,4a-beta,5-beta,6-beta,6a-alpha,;FORSKOLIN FROM COLEUS FORSKOHLII. CAS No. 66575-29-9. Product ID: PIPE-0355. Molecular formula: C22H34O7. Mole weight: 410.5. EINECS: 266-410-9. SMILES: CC(=O)O[C@H]1[C@H]([C@@H]2[C@]([C@H](CCC2(C)C)O)([C@@]3([C@@]1(O[C@@](CC3=O)(C)C=C)C)O)C)O. Appearance: Powder. Category: Natural Extract.
Forskolin
Forskolin - Product ID: NST-10-164. Category: Terpenes. Alternative Names: (-)-Forskolin, Coleonol, Colforsin, ForsLean. Purity: 98%. Test method: HPLC. CAS No. 66575-29-9. Pack Sizes: 0,05g, 0,1g, 0,25g, 0,5g. Appearance: White powder. Molecular formula: C22H34O7. Mole weight: 410.5. Storage: +2 +8 °C.
Forskolin
Forskolin. Group: Biochemicals. Alternative Names: Coleonol; Colforsin, Boforsin. Grades: Plant Grade. CAS No. 66575-29-9. Pack Sizes: 20mg. Molecular Formula: C22H34O7, Molecular Weight: 410.500999999999. US Biological Life Sciences.
Worldwide
Forskolin
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardschiral molecules.
Forskolin
Forskolin is a diterpene isolated from Coleus forskohlii, possessing vasodilating and cardiostimulatory properties. Forskolin resensitizes cell receptors by activating the enzyme adenylyl cyclase and increasing the intracellular levels of cAMP. Group: Biochemicals. Alternative Names: (3R, 4aR, 5S, 6S, 6aS, 10S, 10aR, 10bS)-5-(Acetyloxy)-3-ethenyldodecahydro-6, 10, 10b-trihydroxy-3, 4a, 7, 7, 10a-pentamethyl-1H-Naphtho[2, 1-b]pyran-1-one; (-)-Forskolin; Coleonol; Colforsin; ForsLean; HL 362; L 75-1362B; NSC 357088. Grades: Highly Purified. CAS No. 66575-29-9. Pack Sizes: 25mg. US Biological Life Sciences.
Forskolin is a naturally occurring diterpene from the Indian plant, Coleus forskohlii, that works as an activator of adenylate cyclase resulting in an increase in the intracellular concentration of cAMP. Group: Biochemicals. Grades: Highly Purified. CAS No. 66575-29-9. Pack Sizes: 50mg. US Biological Life Sciences.
Forskolin is a powerful activator of adenyklate cyclase, resulting in an increase of intracellular cAMP concentration.1,2 Activates adenylate cyclase leading to an increase in the intracellular concentration of cAMP. Widely used tool for the investigation of the role of cAMP as a second messenger with a broad range of potential therapeutic applications. Inotropic agent and vasodilator. Induces platelet aggregation. Inhibits ion channels by a mechanism that does not involve cAMP. Non-competitive inhibitor of nicotinic acetylcholine receptors. Group: Biochemicals. Grades: Highly Purified. CAS No. 66575-29-9. Pack Sizes: 10mg, 25mg, 100mg. US Biological Life Sciences.
Activates adenylate cyclase leading to an increase in the intracellular concentration of cAMP. Group: Biochemicals. Grades: Highly Purified. CAS No. 66575-29-9. Pack Sizes: 5mg. US Biological Life Sciences.
Potent, cell permeable adenylyl cyclase activator. Increases intracellular cAMP levels. Widely used tool to investigate cAMP as a second messenger. Inotropic and antihypertensive. Smooth muscle relaxant/vasodilator. Glucose transporter inhibitor. Platelet aggregation inhibitor. Stimulates lipolysis in fat cells. Non-competitive nicotinic acetylcholine receptors inhibitor. MAP kinase inhibitor. Upregulates mitochondrial uncoupling protein (UCP) mRNA levels in brown adipose tissue. Autophagy inhibitor. Hedgehog signaling inhibitor. Has antiglaucoma potential. Promotes neuronal differentiation of NSCs. Group: Biochemicals. Grades: Highly Purified. CAS No. 66575-29-9. Pack Sizes: 1mg, 5mg, 25mg, 50mg. US Biological Life Sciences.
Worldwide
Forskolin (Coleus forskohlii)
The major cell-permeable diterpene isolated from the Indian plant Coleus forskohlii. At low doses, it acts as a positive inotropic agent. At higher doses, it serves as a hypotensive and vasodilatory agent due to its actions as a smooth muscle relaxant. No major side effects are observed at effective doses. Forskolins pharmacological activities are due to its activation of adenylate cyclase (EC50 = 4uM), resulting in increased cAMP levels. The exact mechanism of forskolins positive inotropic effect is unknown but may be related to a cAMP-dependent increase in Na+ permeability that results in indirect augmentation of Ca2+ release. Inhibits MAP kinase in rat renal mesangial cells (IC50 = 25uM). Also acts as a Hh pathway antagonist. Shown to inhibit apoptosis in cerebellar granule cells and to induce apoptosis in resting human B lymphocytes. Group: Biochemicals. Grades: Highly Purified. CAS No. 66575-29-9. Pack Sizes: 5mg. US Biological Life Sciences.
The major cell-permeable diterpene isolated from the Indian plant Coleus forskohlii. At low doses, it acts as a positive inotropic agent. At higher doses, it serves as a hypotensive and vasodilatory agent due to its actions as a smooth muscle relaxant. No major side effects are observed at effective doses. Forskolins pharmacological activities are due to its activation of adenylate cyclase (EC50=4uM), resulting in increased cAMP levels. The exact mechanism of forskolins positive inotropic effect is unknown but may be related to a cAMP-dependent increase in Na+ permeability that results in indirect augmentation of Ca2+ release. Inhibits MAP kinase in rat renal mesangial cells (IC50= 25uM). Also acts as a Hh pathway antagonist. Shown to inhibit apoptosis in cerebellar granule cells and to induce apoptosis in resting human B lymphocytes. Group: Biochemicals. Grades: Highly Purified. CAS No. 66575-29-9. Pack Sizes: 10mg, 25mg. Molecular Formula: C??H??O?. US Biological Life Sciences.
Worldwide
Forskolin Hemisuccinate
Forskolin Hemisuccinate is a derivative fo Forskolin (F701800), a diterpene isolated from Coleus forskohlii, possessing vasodilating and cardiostimulatory properties. Forskolin Hemisuccinate was found to inhibit E-selectin gene transcription through a cAMP-dependent protein kinase pathway. Group: Biochemicals. Alternative Names: 1-[(3R, 4aR, 5S, 6S, 6aS, 10S, 10aR, 10bS)-3-Ethenyldodecahydro-6, 10, 10b-trihydroxy-3, 4a, 7, 7, 10a-pentamethyl-1-oxo-1H-naphtho[2, 1-b]pyran-5-yl] Ester Butanedioic Acid; 1H-Naphtho[2,1-b]pyran, Butanedioic Acid Deriv. Grades: Highly Purified. CAS No. 83797-56-2. Pack Sizes: 1mg. US Biological Life Sciences.
Forssman Antigen Pentaose is a paramount compound, serving as an invaluable instrument for the scrutiny and assessment of Forssman antigens. Tailored meticulously, it can used to study the diseases correlating with the existence of Forssman antigens, inclusive of the enigmatic Forssman syndrome. Synonyms: GalNAc-a-1,3-GalNAc-b-1,3-Gal-a-1,4-Gal-b1,4Glc. Molecular formula: C34H58N2O26. Mole weight: 910.82.
Forssman antigen triaose
Forssman antigen triaose is an invaluable compound in the realm of biomedical inquiry, standing as a pivotal catalyst in the advancement of diagnostic assays and vaccines, specifically tailored to study the intricate nature of Forssman antigen-induced ailments. Synonyms: GalNAc-a-1,3-GalNAc-b-1,3-Gal. Molecular formula: C22H38N2O16. Mole weight: 586.54.
Forsythoside A
Forsythoside A. Group: Biochemicals. Alternative Names: Forsythiaside. Grades: Plant Grade. CAS No. 79916-77-1. Pack Sizes: 20mg. Molecular Formula: C29H36O15, Molecular Weight: 624.586999999999. US Biological Life Sciences.
Worldwide
Forsythoside A
Forsythoside A is a phenylethanoid glycoside found in Forsythiae fructus, which exhibits anti-inflammatory and antibacterial activity. Synonyms: Forsythiaside. Grade: >98%. CAS No. 79916-77-1. Molecular formula: C29H36O15. Mole weight: 624.59.
Forsythoside B
Forsythoside B. Group: Biochemicals. Grades: Plant Grade. CAS No. 81525-13-5. Pack Sizes: 20mg. Molecular Formula: C34H44O19, Molecular Weight: 756.7. US Biological Life Sciences.
Worldwide
Forsythoside B
Forsythoside B is a phenylethanoid glycoside isolated from Forsythia suspensa (Thunb.) Vahl, a Chinese folk medicinal plant for treating inflammatory diseases and promoting blood circulation. Forsythoside B could inhibit TNF-alpha, IL-6, I?B and modulate NF-?B. Uses: Scientific research. Group: Natural products. CAS No. 81525-13-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0029.
Forsythoside E
Forsythoside E. Group: Biochemicals. Grades: Plant Grade. CAS No. 93675-88-8. Pack Sizes: 20mg. Molecular Formula: C20H30O12, Molecular Weight: 462.44. US Biological Life Sciences.
Worldwide
Forsythoside H
Forsythoside H. Group: Biochemicals. CAS No. 1178974-85-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Forsythoside I
Forsythoside I. Group: Biochemicals. CAS No. 1177581-50-8. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Fortimicin A
Produced by the strain of Micromonospora olivoasterospora, it has broad antibacterial spectrum and strong antibacterial activity, and is also effective to aminoglycoside antibiotic resistant bacteria producing 3'-phosphotransferase, 2''-nucleoside transferase, 6' and 2'-acetyltransferase. Synonyms: Astromicin; Astromicina; Astromicine; Astromicinum; Antibiotic KW-1070; 4-Amino-1-((aminoacetyl)methylamino)-1,4-dideoxy-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-beta-L-lyxo-heptopyranosyl)-6-O-methyl-L-chiro-inositol. Grade: 95%. CAS No. 55779-06-1. Molecular formula: C17H35N5O6. Mole weight: 405.49.
Fortimicin B
Produced by the strain of Micromonospora olivoasterospora, it has a weak antibacterial activity. Synonyms: Astromicin B; 4-Amino-1,4-dideoxy-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-beta-L-lyxo-heptopyranosyl)-6-O-methyl-1-(methylamino)-L-chiro-inositol. CAS No. 54783-95-8. Molecular formula: C15H32N4O5. Mole weight: 348.44.
Fortunellin
Fortunellin is a potential anti-inflammation agent in inflammatory diseases, it targets miR-374a, which is a negative regulator of phosphatase and tensin homolog (PTEN). Fortunellin protects against high fructose-induced diabetic heart injury in mice by suppressing inflammation and oxidative stress via AMPK/Nrf-2 pathway regulation. Synonyms: 7-[[2-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one; Acacetin 7-O-neohesperidoside. CAS No. 20633-93-6. Molecular formula: C28H32O14. Mole weight: 592.55.
Fortunellin
Fortunellin, is a flavonoid, that can be isolated from the fruits of Fortunella margarita (kumquat). Fortunellin exhibits little toxicity to mice and suppresses inflammation and ROS generation in H9C2 cells induced by LPS. Fortunellin protects against fructose-induced inflammation and oxidative stress by enhancing AMPK/Nrf2 pathway. Fortunellin can be used for diabetic cardiomyopathy research[1]. Uses: Scientific research. Group: Natural products. CAS No. 20633-93-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-119678.
Forward Reaction Buffer 10X
Foward reaction buffer (10X) for P4410. Group: Molecular Biology. Alternative Names: For use with T4 polynucleotide kinase. Pack Sizes: 400ul, 2x1ml. US Biological Life Sciences.