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| Product | Description | |
|---|---|---|
| Forskolin | Forskolin Inhibitor. Uses: Scientific use. Product Category: T2939. CAS No. 66575-29-9. |  |
| Forskolin (7b-Acetoxy-8,13-epoxy-1a,6b,9a-trihydroxy- labd-14-ene-11-one, Coleonol, Colforsin) | Forskolin is a naturally occurring diterpene from the Indian plant, Coleus forskohlii, that works as an activator of adenylate cyclase resulting in an increase in the intracellular concentration of cAMP. Group: Biochemicals. Grades: Highly Purified. CAS No. 66575-29-9. Pack Sizes: 50mg. US Biological Life Sciences. |  Worldwide |
| Forskolin (7b-Acetoxy-8,13-epoxy-1a,6b,9a-trihydroxy- labd-14-ene-11-one, Colforsin) | Forskolin is a powerful activator of adenyklate cyclase, resulting in an increase of intracellular cAMP concentration.1,2 Activates adenylate cyclase leading to an increase in the intracellular concentration of cAMP. Widely used tool for the investigation of the role of cAMP as a second messenger with a broad range of potential therapeutic applications. Inotropic agent and vasodilator. Induces platelet aggregation. Inhibits ion channels by a mechanism that does not involve cAMP. Non-competitive inhibitor of nicotinic acetylcholine receptors. Group: Biochemicals. Grades: Highly Purified. CAS No. 66575-29-9. Pack Sizes: 10mg, 25mg, 100mg. US Biological Life Sciences. | Worldwide |
| Forskolin (7b-Acetoxy-8,13-epoxy-1a,6b,9a-trihydroxy-labd-14-ene-11-one, Colforsin) | Activates adenylate cyclase leading to an increase in the intracellular concentration of cAMP. Group: Biochemicals. Grades: Highly Purified. CAS No. 66575-29-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Forskolin (Boforsin, Colforsin, Coleonol, NSC 357088, NSC 375489) | Potent, cell permeable adenylyl cyclase activator. Increases intracellular cAMP levels. Widely used tool to investigate cAMP as a second messenger. Inotropic and antihypertensive. Smooth muscle relaxant/vasodilator. Glucose transporter inhibitor. Platelet aggregation inhibitor. Stimulates lipolysis in fat cells. Non-competitive nicotinic acetylcholine receptors inhibitor. MAP kinase inhibitor. Upregulates mitochondrial uncoupling protein (UCP) mRNA levels in brown adipose tissue. Autophagy inhibitor. Hedgehog signaling inhibitor. Has antiglaucoma potential. Promotes neuronal differentiation of NSCs. Group: Biochemicals. Grades: Highly Purified. CAS No. 66575-29-9. Pack Sizes: 1mg, 5mg, 25mg, 50mg. US Biological Life Sciences. | Worldwide |
| Forskolin (Coleus forskohlii) | The major cell-permeable diterpene isolated from the Indian plant Coleus forskohlii. At low doses, it acts as a positive inotropic agent. At higher doses, it serves as a hypotensive and vasodilatory agent due to its actions as a smooth muscle relaxant. No major side effects are observed at effective doses. Forskolins pharmacological activities are due to its activation of adenylate cyclase (EC50 = 4uM), resulting in increased cAMP levels. The exact mechanism of forskolins positive inotropic effect is unknown but may be related to a cAMP-dependent increase in Na+ permeability that results in indirect augmentation of Ca2+ release. Inhibits MAP kinase in rat renal mesangial cells (IC50 = 25uM). Also acts as a Hh pathway antagonist. Shown to inhibit apoptosis in cerebellar granule cells and to induce apoptosis in resting human B lymphocytes. Group: Biochemicals. Grades: Highly Purified. CAS No. 66575-29-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Forskolin, Coleus forskohlii (7b-Acetoxy-8,13-epoxy-1α,6 β,9α-trihydroxy-labd-14-en-11-one, Colforsin) | The major cell-permeable diterpene isolated from the Indian plant Coleus forskohlii. At low doses, it acts as a positive inotropic agent. At higher doses, it serves as a hypotensive and vasodilatory agent due to its actions as a smooth muscle relaxant. No major side effects are observed at effective doses. Forskolins pharmacological activities are due to its activation of adenylate cyclase (EC50=4uM), resulting in increased cAMP levels. The exact mechanism of forskolins positive inotropic effect is unknown but may be related to a cAMP-dependent increase in Na+ permeability that results in indirect augmentation of Ca2+ release. Inhibits MAP kinase in rat renal mesangial cells (IC50= 25uM). Also acts as a Hh pathway antagonist. Shown to inhibit apoptosis in cerebellar granule cells and to induce apoptosis in resting human B lymphocytes. Group: Biochemicals. Grades: Highly Purified. CAS No. 66575-29-9. Pack Sizes: 10mg, 25mg. Molecular Formula: C??H??O?. US Biological Life Sciences. | Worldwide |
| Forskolin Hemisuccinate | Forskolin Hemisuccinate is a derivative fo Forskolin (F701800), a diterpene isolated from Coleus forskohlii, possessing vasodilating and cardiostimulatory properties. Forskolin Hemisuccinate was found to inhibit E-selectin gene transcription through a cAMP-dependent protein kinase pathway. Group: Biochemicals. Alternative Names: 1-[(3R, 4aR, 5S, 6S, 6aS, 10S, 10aR, 10bS)-3-Ethenyldodecahydro-6, 10, 10b-trihydroxy-3, 4a, 7, 7, 10a-pentamethyl-1-oxo-1H-naphtho[2, 1-b]pyran-5-yl] Ester Butanedioic Acid; 1H-Naphtho[2,1-b]pyran, Butanedioic Acid Deriv. Grades: Highly Purified. CAS No. 83797-56-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Forskolin Hemisuccinate-13C4 | Forskolin Hemisuccinate-13C4. Group: Biochemicals. Alternative Names: 1-[(3R, 4aR, 5S, 6S, 6aS, 10S, 10aR, 10bS)-3-Ethenyldodecahydro-6, 10, 10b-trihydroxy-3, 4a, 7, 7, 10a-pentamethyl-1-oxo-1H-naphtho[2, 1-b]pyran-5-yl] Ester Butanedioic Acid-13C4; 1H-Naphtho[2,1-b]pyran Butanedioic Acid Deriv.-13C4. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C2013C4H36O9, Molecular Weight: 472.51. US Biological Life Sciences. | Worldwide |
| Forssman antigen pentaose | Forssman Antigen Pentaose is a paramount compound, serving as an invaluable instrument for the scrutiny and assessment of Forssman antigens. Tailored meticulously, it can used to study the diseases correlating with the existence of Forssman antigens, inclusive of the enigmatic Forssman syndrome. Synonyms: GalNAc-a-1,3-GalNAc-b-1,3-Gal-a-1,4-Gal-b1,4Glc. Molecular formula: C34H58N2O26. Mole weight: 910.82. |  |
| Forssman antigen triaose | Forssman antigen triaose is an invaluable compound in the realm of biomedical inquiry, standing as a pivotal catalyst in the advancement of diagnostic assays and vaccines, specifically tailored to study the intricate nature of Forssman antigen-induced ailments. Synonyms: GalNAc-a-1,3-GalNAc-b-1,3-Gal. Molecular formula: C22H38N2O16. Mole weight: 586.54. | |
| Forsythoside A | Forsythoside A. Group: Biochemicals. Alternative Names: Forsythiaside. Grades: Plant Grade. CAS No. 79916-77-1. Pack Sizes: 20mg. Molecular Formula: C29H36O15, Molecular Weight: 624.586999999999. US Biological Life Sciences. | Worldwide |
| Forsythoside A | Forsythoside A is a phenylethanoid glycoside found in Forsythiae fructus, which exhibits anti-inflammatory and antibacterial activity. Synonyms: Forsythiaside. Grade: >98%. CAS No. 79916-77-1. Molecular formula: C29H36O15. Mole weight: 624.59. | |
| Forsythoside B | Forsythoside B. Group: Biochemicals. Grades: Plant Grade. CAS No. 81525-13-5. Pack Sizes: 20mg. Molecular Formula: C34H44O19, Molecular Weight: 756.7. US Biological Life Sciences. | Worldwide |
| Forsythoside B | Forsythoside B is a phenylethanoid glycoside isolated from Forsythia suspensa (Thunb.) Vahl, a Chinese folk medicinal plant for treating inflammatory diseases and promoting blood circulation. Forsythoside B could inhibit TNF-alpha, IL-6, I?B and modulate NF-?B. Uses: Scientific research. Group: Natural products. CAS No. 81525-13-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0029. |  |
| Forsythoside E | Forsythoside E. Group: Biochemicals. Grades: Plant Grade. CAS No. 93675-88-8. Pack Sizes: 20mg. Molecular Formula: C20H30O12, Molecular Weight: 462.44. US Biological Life Sciences. | Worldwide |
| Forsythoside H | Forsythoside H. Group: Biochemicals. CAS No. 1178974-85-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Forsythoside I | Forsythoside I. Group: Biochemicals. CAS No. 1177581-50-8. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Fortimicin A | Produced by the strain of Micromonospora olivoasterospora, it has broad antibacterial spectrum and strong antibacterial activity, and is also effective to aminoglycoside antibiotic resistant bacteria producing 3'-phosphotransferase, 2''-nucleoside transferase, 6' and 2'-acetyltransferase. Synonyms: Astromicin; Astromicina; Astromicine; Astromicinum; Antibiotic KW-1070; 4-Amino-1-((aminoacetyl)methylamino)-1,4-dideoxy-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-beta-L-lyxo-heptopyranosyl)-6-O-methyl-L-chiro-inositol. Grade: 95%. CAS No. 55779-06-1. Molecular formula: C17H35N5O6. Mole weight: 405.49. | |
| Fortimicin B | Produced by the strain of Micromonospora olivoasterospora, it has a weak antibacterial activity. Synonyms: Astromicin B; 4-Amino-1,4-dideoxy-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-beta-L-lyxo-heptopyranosyl)-6-O-methyl-1-(methylamino)-L-chiro-inositol. CAS No. 54783-95-8. Molecular formula: C15H32N4O5. Mole weight: 348.44. | |
| Fortunellin | Fortunellin is a potential anti-inflammation agent in inflammatory diseases, it targets miR-374a, which is a negative regulator of phosphatase and tensin homolog (PTEN). Fortunellin protects against high fructose-induced diabetic heart injury in mice by suppressing inflammation and oxidative stress via AMPK/Nrf-2 pathway regulation. Synonyms: 7-[[2-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one; Acacetin 7-O-neohesperidoside. CAS No. 20633-93-6. Molecular formula: C28H32O14. Mole weight: 592.55. | |
| Fortunellin | Fortunellin, is a flavonoid, that can be isolated from the fruits of Fortunella margarita (kumquat). Fortunellin exhibits little toxicity to mice and suppresses inflammation and ROS generation in H9C2 cells induced by LPS. Fortunellin protects against fructose-induced inflammation and oxidative stress by enhancing AMPK/Nrf2 pathway. Fortunellin can be used for diabetic cardiomyopathy research[1]. Uses: Scientific research. Group: Natural products. CAS No. 20633-93-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-119678. | |
| Forward Reaction Buffer 10X | Foward reaction buffer (10X) for P4410. Group: Molecular Biology. Alternative Names: For use with T4 polynucleotide kinase. Pack Sizes: 400ul, 2x1ml. US Biological Life Sciences. | Worldwide |
| Fosalvudine tidoxil | Fosalvudine tidoxil is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Fosalvudine tidoxil is a prodrug derived from Alovudine (HY-B1516). Fosalvudine tidoxil is less toxic than Alovudine and can be used for the research of HIV-1 infection. Uses: Designed for use in research and industrial production. Additional or Alternative Names: FOSALVUDINE TIDOXIL. Product Category: Inhibitors. CAS No. 763903-67-9. Molecular formula: C35H64FN2O8PS. Mole weight: 722.935. Canonical SMILES: O=P(OC[C@H]1O[C@@H](N(C(N2)=O)C=C(C)C2=O)C[C@@H]1F)(OCC(OCCCCCCCCCC)CSCCCCCCCCCCCC)O. Product ID: ACM763903679. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Fosamprenavir | Fosamprenavir (Amprenavir phosphate;GW 433908) is a phosphate ester proagent of the antiretroviral protease inhibitor Amprenavir, with improved solubility [1]. Anti- HIV infection [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Amprenavir phosphate; GW 433908. CAS No. 226700-79-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-78726. | |
| Fosamprenavir | Fosamprenavir, also called as GW433908, Lexiva and Telzir, is an oral prodrug of the protease inhibitor (PI) amprenavir. Combined with other antiretroviral agents, Fosamprenavir is indicated for the treatment of patients with HIV infection, particularly those who have not previously received antiretroviral therapy. Synonyms: [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-1-phenyl-3-phosphonooxybutan-2-yl]carbamate; 3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-1-(phenylmethyl)-2-(phosphonooxy)propyl)carbamic acid C-(tetrahydro-3-furanyl) ester; fosamprenavir; 226700-81-8 (calcium) GW 433908; GW-433908; GW-908. Grade: > 95%. CAS No. 226700-79-4. Molecular formula: C25H36N3O9PS. Mole weight: 585.62. | |
| Fosamprenavir calcium | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Fosamprenavir calcium salt | Fosamprenavir calcium salt. Group: Biochemicals. Alternative Names: GW-433908G; Lexiva; Telzir. Grades: Highly Purified. CAS No. 226700-81-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C25H34CaN3O9PS. US Biological Life Sciences. | Worldwide |
| Fosamprenavir Calcium Salt | HIV protease inhibitor; water soluble prodrug of amprenavir. Synonyms: GW 433908G; Lexiva; GW433908G; GW-433908G. Grade: >98%. CAS No. 226700-81-8. Molecular formula: C25H34CaN3O9PS. Mole weight: 623.67. | |
| Fosamprenavir Calcium Salt (GW-433908G, Lexiva, Telzir) | HIV protease inhibitor; water soluble prodrug of amprenavir. Group: Biochemicals. Alternative Names: GW-433908G; Lexiva; Telzir. Grades: Highly Purified. CAS No. 226700-81-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Fosamprenavir-[d4] Calcium Salt | Fosamprenavir-[d4] Calcium Salt is the labelled analogue of Fosamprenavir Calcium Salt, which is an HIV protease inhibitor and a water soluble prodrug of amprenavir. Synonyms: Fosamprenavir-D4 Calcium Salt; GW-433908G-d4; Lexiva-d4; Telzir-d4. Grade: 98%; ≥99% atom D. Molecular formula: C25H30D4CaN3O9PS. Mole weight: 627.69. | |
| Fosamprenavir-d4 Calcium Salt (GW-433908G-d4, Lexiva-d4, Telzir-d4) | HIV protease inhibitor; water soluble prodrug of amprenavir. Group: Biochemicals. Alternative Names: GW-433908G-d4; Lexiva-d4; Telzir-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Fosamprenavir-[d9] | Fosamprenavir-[d9] is a deuterium labelled form of Fosamprenavir, which is a drug for the treatment of HIV infections. Synonyms: Fosamprenavir D9. Molecular formula: C25H27D9N3O9PS. Mole weight: 594.66. | |
| Fosamprenavir enantiomer | Fosamprenavir enantiomer is a sterling antiretroviral agent obstructing the protease enzyme's nefarious endeavor and impeding the pernicious propagation and replication of the viral intruder. Grade: > 95%. Molecular formula: C25H36N3O9PS. Mole weight: 585.62. | |
| Fosamprenavir Related Compound | Fosamprenavir Related Compound is a impurity of Fosamprenavir, an astounding antiviral drug unfailingly harnessed against the relentless HIV/AIDS affliction. Grade: > 95%. Molecular formula: C20H30N3O6PS. Mole weight: 471.52. | |
| Fosamprenavir USP Related Compound A | An impurity of Fosamprenavir. Fosamprenavir is an antiviral medication used to treat HIV-1 infection. It is a prodrug of amprenavir and works by inhibiting the HIV protease enzyme, thereby preventing the virus from replicating. Synonyms: Calcium (6R,7S,16S,17R)-4,19-bis[(4-aminophenyl)sulfonyl]-7,16-dibenzyl-2,21-dimethyl-9,14-dioxo-10,13-dioxa-4,8,15,19-tetraazadocosane-6,17-diyl bis(phosphate); USP Fosamprenavir Related Compound A; Fosamprenavir Related Compound A; Fosamprenavir Calcium Related Compound A; Fosamprenavir Ethylene Glycol Dimer Calcium Salt. Grade: ≥95%. Molecular formula: C44H58Ca2N6O16P2S2. Mole weight: 1133.20. | |
| Fosaprepitant | Fosaprepitant is a selective neurokinin-1 (NK-1) receptor antahonist. It is an antiemetic drug, which is a Aprepitant prodrug. Uses: Antiemetics. Synonyms: P-[3-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonic Acid; L 758298; [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)mor. Grade: > 95%. CAS No. 172673-20-0. Molecular formula: C23H22F7N4O6P. Mole weight: 614.42. | |
| Fosaprepitant | Fosaprepitant (L-785298) is a proagent of Aprepitant (HY-10052). Fosaprepitant is a neurokinin-1 receptor antagonist, which is development for the prevention of chemotherapy-induced nausea and vomiting (CINV) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L-758298. CAS No. 172673-20-0. Pack Sizes: 1 mg. Product ID: HY-14407. | |
| Fosaprepitant-[d4] | One of the isotopic labelled form of Fosaprepitant, which has been found to be a selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: P-[3-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonic Acid-d4; Fosaprepitant D4. Grade: >98%. Molecular formula: C23H18D4F7N4O6P. Mole weight: 618.43. | |
| Fosaprepitant-[d4] Dimeglumine | Fosaprepitant-[d4] Dimeglumine is a labelled form of Fosaprepitant Dimeglumine, which has been found to be a selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl-d4)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonate 1-Deoxy-1-(methylamino)-D-glucitol; Fosaprepitant D4 Dimeglumine; MK-0517-d4; L785298-d4. Molecular formula: C37H52D4F7N6O16P. Mole weight: 1008.86. | |
| Fosaprepitant Dibenzyl Ester | Fosaprepitant Dibenzyl Ester is a reactant in the synthesis of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(Trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]-phosphonic Acid bis(Phenylmethyl) Ester; Dibenzyl Fosaprepitant; Fosaprepitant Impurity 16; Phosphonic acid, P-[3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]-, bis(phenylmethyl) ester; 2-Bis(phenylmethoxy)phosphoryl-5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-4H-1,2,4-triazol-3-one. Grade: >95%. CAS No. 265121-01-5. Molecular formula: C37H34F7N4O6P. Mole weight: 794.65. | |
| Fosaprepitant dimeglumine | Fosaprepitant dimeglumine (MK-0517) is a proagent of Aprepitant (HY-10052). Fosaprepitant dimeglumine is a neurokinin-1 receptor antagonist, which is development for the prevention of chemotherapy-induced nausea and vomiting (CINV) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-0517; L785298. CAS No. 265121-04-8. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14407A. | |
| Fosaprepitant dimeglumine | Fosaprepitant is a selective NK-1 receptor antahonist. It is a water-soluble phosphoryl prodrug for Aprepitant. Synonyms: MK-0517; MK 0517; MK0517. Grade: >98%. CAS No. 265121-04-8. Molecular formula: C23H22F7N4O6P.2C7H17NO5. Mole weight: 1004.83. | |
| Fosaprepitant Dimeglumine | Fosaprepitant is a selective neurokinin-1 (NK-1) receptor antahonist. Fosaprepitant is an antiemetic drug, a Aprepitant prodrug. Group: Biochemicals. Alternative Names: [3-[[ (2R, 3S) -2-[ (1R) -1-[3, 5-bis (trifluoromethyl) phenyl]ethoxy]-3- (4-fluorophenyl) -4-morpholinyl]methyl]-2, 5-dihydro-5-oxo-1H-1, 2, 4-triazol-1-yl]phosphonate 1-Deoxy-1-(methylamino)-D-glucitol; MK 0517. Grades: Highly Purified. CAS No. 265121-04-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Fosaprepitant Dimeglumine | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopychiral molecules. Alternative Names: D-Glucitol, 1-deoxy-1-(methylamino)-, [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonate (2:1) (salt) (9CI), Fosaprepitant di(N-methylglucamine), Phosphonic acid, [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]-, compd. with 1-deoxy-1-(methylamino)-D-glucitol (1:2) (9CI),D-Glucitol, 1-deoxy-1-(methylamino)-, [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonate (2:1), Fosaprepitant dimeglumine, MK 0517. | |
| Fosaprepitant Impurity 1 | A metabolite of Aprepitant. Synonyms: [2R-[2α(S*),3α]]-5-[[2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-Triazol-3-one. Grade: > 95%. CAS No. 170902-81-5. Molecular formula: C23H21F7N4O3. Mole weight: 534.44. | |
| Fosaprepitant Impurity 2 | A metabolite of Aprepitant. Synonyms: [2R-[2α(R*),3α]]-5-[[2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-oxido-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one. Grade: > 95%. CAS No. 172673-23-3. Molecular formula: C23H21F7N4O4. Mole weight: 550.44. | |
| Fosaprepitant Impurity 3 | A metabolite of Aprepitant. Synonyms: (2R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-4-(phenylmethyl)-3-morpholinone. Grade: > 95%. CAS No. 287930-75-0. Molecular formula: C21H19F6NO3. Mole weight: 447.38. | |
| Fosaprepitant Morpholine | Fosaprepitant Morpholine is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: Fosaprepitant Impurity 27; Morpholine, 2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-, (2S,3S)-; Aprepitant M2 Metabolite (1R,2S,3S)-Isomer; Aprepitant impurity 20; (2S,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine. Grade: ≥95%. CAS No. 170902-80-4. Molecular formula: C20H18F7NO2. Mole weight: 437.35. | |
| Fosaprepitant N-Benzyl Impurity | Fosaprepitant N-Benzyl Impurity. Grade: > 95%. Molecular formula: C30H28F7N4O6P. Mole weight: 704.54. | |
| Fosaprepitant N-oxide | Fosaprepitant N-oxide is an impurity of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: (3-{[(2R,3S)-2-{(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy}-3-(4-fluorophenyl)-4-oxido-4-morpholinyl]methyl}-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid; Phosphonic acid, [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-oxido-4-morpholinyl]methyl]-4,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]-. Molecular formula: C23H22F7N4O7P. Mole weight: 630.41. | |
| Fosbretabulin | Fosbretabulin, also called as CA4P, has antitumor activity against anaplastic thyroid cancer (ATC) cell lines. Fosbretabulin, a novel water-soluble vascular-disrupting agent, is a phosphate derivative of a natural stilbenoid phenol derived from the African bush willow (Combretum caffrum). Synonyms: [2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl] dihydrogen phosphate; 3,4,5-trimethoxy-3'-hydroxy-4'-methoxystilbene; CA4DP; combretastatin A-4; 168555-66-6 (fosbretabulin disodium); 82855-09-2 (combretastatin); 117048 -59-6 (combretastatin A4). Grade: >98%. CAS No. 222030-63-9. Molecular formula: C18H21O8P. Mole weight: 396.33. | |
| Fosbretabulin disodium | Fosbretabulin disodium is the disodium salt of a water-soluble phosphate derivative of a natural stilbenoid phenol derived from the African bush willow (Combretum caffrum) with potential vascular disrupting and antineoplastic activities. Upon administration, the prodrug fosbretabulin is dephosphorylated to its active metabolite, the microtubule-depolymerizing agent combretastatin A4, which binds to tubulin dimers and prevents microtubule polymerization, resulting in mitotic arrest and apoptosis in endothelial cells. In addition, this agent disrupts the engagement of the endothelial cell-specific junctional molecule vascular endothelial-cadherin (VE-cadherin) and so the activity of the VE-cadherin/β-catenin/Akt signaling pathway, which may result in the inhibition of endothelial cell migration and capillary tube formation. As a result of fosbretabulin's dual mechanism of action, the tumor vasculature collapses, resulting in reduced tumor blood flow and ischemic necrosis of tumor tissue. Synonyms: Combretastatin A-4 phosphate disodium, CA4P; CA4DP; Combretastatin A-4 phosphate. CAS No. 168555-66-6. Molecular formula: C18H19Na2O8P. Mole weight: 440.295. | |
| Fosbretabulin disodium | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Fosbretabulin disodium | Fosbretabulin disodium (CA 4DP) is a tubulin destabilizing agent. Fosbretabulin disodium is the Combretastatin A4 proagent that selectively targets endothelial cells, induces regression of nascent tumour neovessels, reduces tumour blood flow and causes central tumour necrosis[1][3]. Uses: Scientific research. Group: Natural products. Alternative Names: CA 4DP; CA 4P; Combretastatin A4 disodium phosphate. CAS No. 168555-66-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17449. | |
| Foscarbidopa | Foscarbidopa (ABBV-951; Carbidopa 4-monophosphate) is a proagent of Carbidopa, acts as a dopamine receptor agonist [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABBV-951; Carbidopa 4-monophosphate. CAS No. 1907685-81-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109131. | |
| Foscarbidopa | Foscarbidopa, a prodrug of Carbidopa, is a dopamine receptor agonist. Synonyms: Carbidopa 4'-monophosphate; (αS)-α-Hydrazinyl-3-hydroxy-α-methyl-4-(phosphonooxy)-benzenepropanoic Acid; Benzenepropanoic acid, α-hydrazinyl-3-hydroxy-α-methyl-4-(phosphonooxy)-, (αS)-; Carbidopa 4'-Phosphate. Grade: ≥95%. CAS No. 1907685-81-7. Molecular formula: C10H15N2O7P. Mole weight: 306.21. | |
| Foscarnet | Foscarnet is a pyrophosphate analog DNA polymerase inhibitor that has activity against several viruses, but is primarily used to treat CMV retinitis. Because it can cross the blood-brain barrier, it can be used to treat viral infections of the central nervous system. Synonyms: Phosphonoformate; Carboxyphosphonic acid; Foscarmet; Phosphonocarboxylic acid; Dihydroxyphosphinecarboxylic acid oxide; Phosphonomethanoic acid; Dihydroxyphosphanecarboxylic acid oxide; Phgosphonocarboxylic acid; NSC313410; Phosphinecarboxylic acid, 1,1-dihydroxy-, 1-oxide; Foscamet. Grade: 95%. CAS No. 4428-95-9. Molecular formula: CH3O5P. Mole weight: 126.01. | |
| Foscarnet Related Compound B | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Foscarnet Related Compound B | Foscarnet Related Compound B is an impurity of Foscarnet, which is a DNA polymerase inhibitor with activity against several viruses. Synonyms: disodium (ethoxyoxidophosphanyl)formate; USP Foscarnet Related Compound B; Disodium (ethoxyoxidophosphoryl)formate + Disodium (ethoxycarbonyl)phosphonate (Mixture). Molecular formula: C3H5Na2O5P. Mole weight: 198.02. | |
| Foscarnet Related Compound D | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Foscarnet sodium | Foscarnet sodium (Trisodium phosphonoformate) is a viral DNA polymerase activity inhibitor, leading to reversible suppression of viral replication. Foscarnet sodium is an antiherpesvirus agent used in cytomegalovirus retinitis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Trisodium phosphonoformate; Phosphonoformic acid trisodium salt. CAS No. 63585-09-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1318. | |
| Foscarnet sodium | Foscarnet Sodium inhibits viral RNA polymerases, reverse transcriptases and DNA polymerases by non-competitive inhibition of dNTPs. It is an antiviral agent used in the treatment of cytomegalovirus retinitis. It has activity against human herpesviruses and HIV. Uses: Antiviral agents. Synonyms: Trisodium phosphonoformate; Trisodium carboxyphosphate; Foscarnet trisodium; Phosphonoformic acid trisodium salt; 1,1-Dihydroxyphosphinecarboxylic Acid 1-Oxide Sodium Salt; A 29622; EHB 776; Gefin; Triapten. Grade: >98%. CAS No. 63585-09-1. Molecular formula: CNa3O5P. Mole weight: 191.95. | |
| Foscarnet sodium | Foscarnet sodium. Group: Biochemicals. Alternative Names: 1, 1-Di hydroxyphosphinecar boxyl ic acid 1-oxide sodium salt; A 29622; EHB 776. Grades: Highly Purified. CAS No. 63585-09-1. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: CNa3O5P. US Biological Life Sciences. | Worldwide |
| Foscarnet sodium | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Foscarnet Sodium | Pharmaceutical Secondary Standard; Certified Reference Material. Group: Pharmacopeia & metrological institutes standards. | |
| Foscarnet Sodium Hexahydrate | Foscarnet Sodium Hexahydrate is an antiviral drug used in the treatment of cytomegalovirus retinitis. It has inhibitory effect on viral DNA polymerase and reverse transcriptase. Synonyms: Sodium phosphonoformate tribasic hexahydrate; 1,1-Dihydroxyphosphinecarboxylic Acid 1-Oxide Sodium Salt Hydrate; A 29622 Hydrate; EHB 776 Hydrate; Foscavir Hydrate; Gefin Hydrate; PFA Hydrate; Phosphonoformic Acid Trisodium Salt Hydrate; Triapten Hexahydrate; Trisodium Phosphonoformate Hexahydrate. Grade: 95%. CAS No. 34156-56-4. Molecular formula: CH12Na3O11P. Mole weight: 300.04. | |
| Foscenvivint | PRI-724 is a selective inhibitor of the CBP/?-catenin interaction. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PRI-724. CAS No. 1422253-38-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112045. | |
| Fos-choline -13,sol-grade | Fos-choline -13,sol-grade. Uses: Designed for use in research and industrial production. Additional or Alternative Names: FOS-CHOLINE?-13, SOL-GRADE?. Product Category: Heterocyclic Organic Compound. CAS No. 85775-42-4. Molecular formula: C18H40NO4P. Mole weight: 365.491. Product ID: ACM85775424. Alfa Chemistry ISO 9001:2015 Certified. | |
| Fosciclopirox | Fosciclopirox suppresses growth of urothelial cancer by targeting the γ-secretase complex. Fosciclopirox selectively delivers the active metabolite, Ciclopirox (CPX), to the entire urinary tract [1] [2]. Ciclopirox has anticancer activity in a number of solid and hematologic malignancies. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CPX-POM. CAS No. 1380539-06-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109174. | |
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