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| Product | Description | |
|---|---|---|
| Fosmanogepix | Fosmanogepix (APX001) is a broad-spectrum agent against invasive fungal infections. Fosmanogepix (APX001) targets the conserved Gwt1 enzyme required for the localization of glycosylphosphatidylinositol-anchored mannoproteins in fungi. This inhibition prevents the appropriate localization of cell wall mannoproteins, which compromises cell wall integrity, biofilm formation, germ tube formation, and fungal growth. Fosmanogepix (APX001) can be used for invasive fungal infections research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: APX001; E1211. CAS No. 2091769-17-2. Pack Sizes: 5 mg. Product ID: HY-119726. |  |
| Fosmidomycin | Fosmidomycin is produced by the strain of Streptomyces lavendulae 8006. Fosmidomycin has anti-gram-positive and anti-gram-negative activities. Synonyms: Fosmidomycina; 3-(N-hydroxyformamido)propylphosphonic acid; FR-31564. Grades: 95%. CAS No. 66508-53-0. Molecular formula: C4H10NO5P. Mole weight: 183.10. |  |
| Fosmidomycin sodium salt | Fosmidomycin sodium salt. Group: Biochemicals. Alternative Names: 3-(N-Formyl-N-hydroxyamino)propyl phosphonic acid sodium salt; FR31564. Grades: Highly Purified. CAS No. 66508-37-0. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C4H9NNaO5P. US Biological Life Sciences. |  Worldwide |
| Fosmidomycin sodium salt | Fosmidomycin sodium salt is a phosphonic acid antibiotic and a antimalarial agent, which is active against both Gram-negative and Gram-positive bacteria. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FR-31564. CAS No. 66508-37-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-112853. | |
| Fosmidomycin sodium salt | Fosmidomycin is an antimalarial and antibiotic originally isolated from culture broths of bacteria of the genus Streptomyces and has been used as an inhibitor of DOXP reductoisomerase, a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis. Synonyms: Antibiotic FR31564; FR31564; P-[3-(formylhydroxyamino)propyl]-phosphonic acid, monosodium salt; (3-(N-Hydroxyformamido)propyl)phosphonic acid sodium salt; Phosphonic acid, (3-(formylhydroxyamino)propyl)-, monosodium salt. Grades: ≥95%. CAS No. 66508-37-0. Molecular formula: C4H9NO5P.Na. Mole weight: 205.08. | |
| Fosmidomycin, Sodium Salt (3-(N-Formyl-N-hydroxyamino)propyl Phosphonic Acid, Sodium Salt, FR31564) | An antibiotic. Group: Biochemicals. Alternative Names: 3-(N-Formyl-N-hydroxyamino)propyl Phosphonic Acid, Sodium Salt, FR31564. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Fosnetupitant | Fosnetupitant (Pronetupitant) a methylene phosphate proagent of Netupitant. Fosnetupitant (Pronetupitant) exhibits a pK i of 9.5 for human NK 1 receptor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Pronetupitant. CAS No. 1703748-89-3. Pack Sizes: 5 mg. Product ID: HY-17615. | |
| Fosnetupitant | Fosnetupitant, a piperazine derivative, has been found to be a NK1 receptor antagonist that could be used in nausea and vomiting caused by chemotherapy. It was just reported a Phase II trail in Japan. Synonyms: Fosnetupitant; T672P80L2S; Fosnetupitant; Piperazinium, 4-(5-((2-(3,5-bis(trifluoromethyl)phenyl)-2-methyl-1-oxopropyl)methylamino)-4-(2-methylphenyl)-2-pyridinyl)-1-methyl-1-((phosphonooxy)methyl)-, inner salt. Grades: 98%. CAS No. 1703748-89-3. Molecular formula: C31H35F6N4O5P. Mole weight: 688.61. | |
| Fosphenytoin sodium | Fosphenytoin sodium. Group: Biochemicals. Alternative Names: 5,5-Diphenyl-3-[(phosphonooxy)methyl]-2,4-imidazolidinedione sodium salt; ACC 9653; ACC 9653-010. Grades: Highly Purified. CAS No. 92134-98-0. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C16H13N2Na2O6P. US Biological Life Sciences. | Worldwide |
| Fosquidone | Fosquidone is a water-soluble pentacyclic pyrolloquinone analogue of mitoquidone with potential antineoplastic activity. Currently, the mechansim of action of fosquidone is unknown. In vitro studies indicate that this agent does not bind to DNA or inhibit topoisomerases. Synonyms: GR 63178K; GR63178A; GR-63178A; NSC 611615; benzyl (14-methyl-8,13-dioxo-5,8,13,14-tetrahydrobenzo[5,6]isoindolo[2,1-b]isoquinolin-9-yl) hydrogen phosphate. CAS No. 114517-02-1. Molecular formula: C28H22NO6P. Mole weight: 499.46. | |
| Fosravuconazole | Fosravuconazole is an azole antifungal agent potentially for the treatment of fungal infections, as a water-soluble prodrug of ravuconazole that is being developed by the Drugs for Neglected Diseases Initiative (DNDi). Uses: A water-soluble prodrug of ravuconazole that is being developed by the drugs for neglected diseases initiative (dndi). Synonyms: Fosravuconazole; BEF-1224; BMS-379224; E-1224; BEF1224; BMS379224; E1224.[(2R,3R)-3-[4-(4-cyanophenyl)-1,3-thiazol-2-yl]-2-(2,4-difluorophenyl)-1-(1,2,4-triazol-1-yl)butan-2-yl]oxymethyl dihydrogen phosphate. Grades: ≥98%. CAS No. 351227-64-0. Molecular formula: C23H20F2N5O5PS. Mole weight: 547.09. | |
| Fosravuconazole | Fosravuconazole (BMS-379224), a proagent of Ravuconazole, is an orally active broad spectrum antifungal agent. Fosravuconazole can be used for candidiasis, onychomycosis and parasitemia research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-379224; E-1224. CAS No. 351227-64-0. Pack Sizes: 1 mg. Product ID: HY-16779. | |
| Fostamatinib | Fostamatinib, a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM, strongly inhibiting Syk but not Lyn, and 5-fold less potent to Flt3. Synonyms: R788; R 788; R-788. Grades: >98%. CAS No. 901119-35-5. Molecular formula: C23H26FN6O9P. Mole weight: 580.46. | |
| Fostamatinib | Fostamatinib (R788) is the oral proagent of the active compound R406 [1]. R406 is an orally available and competitive Syk/FLT3 inhibitor with a K i of 30 nM and an IC 50 of 41 nM [2]. R406 also inhibits Lyn (IC 50 =63 nM) and Lck (IC 50 =37 nM) [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R788. CAS No. 901119-35-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13038A. | |
| Fostamatinib Disodium | Fostamatinib Disodium (R788 Disodium) is the oral proagent of the active compound R406 [1]. R406 is an orally available and competitive Syk/FLT3 inhibitor with a K i of 30 nM and an IC 50 of 41 nM [2]. R406 also inhibits Lyn (IC 50 =63 nM) and Lck (IC 50 =37 nM) [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R788(Disodium). CAS No. 1025687-58-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13038. | |
| Fostamatinib disodium hexahydrate | Fostamatinib disodium hexahydrate. Group: Biochemicals. Alternative Names: 6-[[5-Fluoro-2-[ (3, 4, 5-trimethoxyphenyl) amino]-4-pyrimidinyl]amino]-2, 2-dimethyl-4-[ (phosphonooxy) methyl]-2H-pyrido[3, 2-b]-1, 4-oxazin-3 (4H) -one sodium salt hydrate. Grades: Highly Purified. CAS No. 914295-16-2. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C23H36FN6Na2O15P. US Biological Life Sciences. | Worldwide |
| Fostamatinib sodium | R788 (Fostamatinib) disodium, a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. Phase 3. Synonyms: R935788. Code names: R788 sodium. R935788 sodium. CAS No. 1025687-58-4. Molecular formula: C23H24FN6O9P.2Na. Mole weight: 624.42. | |
| Fostemsavir | Fostemsavir (BMS-663068) is the phosphonooxymethyl prodrug of BMS-626529. Fostemsavir (BMS-663068) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4 + T cells. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-663068. CAS No. 864953-29-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-15440A. | |
| Fostemsavir Tris | Fostemsavir Tris (BMS-663068 (Tris)) is the phosphonooxymethyl proagent of BMS-626529. Fostemsavir Tris (BMS-663068 (Tris)) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4 + T cells. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-663068 Tris. CAS No. 864953-39-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15440B. | |
| Fosthiazate | Fosthiazate is a broad-spectrum nematicide against various plant parasitic nematodes, including Meloidogyne spp. , Globodera spp. , and Pratylenchus spp. , through inhibiting the synthesis of acetylcholinesterase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 98886-44-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W020785. | |
| Fostriecin | The most fully characterised member of a family of phosphate esters of a triene antibiotic; a topoisomerase II inhibitor; selective inhibition of protein phosphatase PP2A. Synonyms: (1E,7E,9E,11E)-3,6,13-trihydroxy-3-methyl-1-(6-oxo-3,6-dihydro-2H-pyran-2-yl)trideca-1,7,9,11-tetraen-4-yl dihydrogen phosphate; 2H-Pyran-2-one, 5,6-dihydro-6-[3,6,13-trihydroxy-3-methyl- 4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-, monosodiumsalt. Grades: >95% by HPLC. CAS No. 87810-56-8. Molecular formula: C19H27O9P. Mole weight: 430.39. | |
| Fostriecin sodium salt | Fostriecin sodium salt is a protein phosphatase types 2A (PP2A) and 4 (PP4) inhibitor (IC50 = 1.5 nM and 3 nM, respectively). It also has an inhibitory effect on topoisomerase II (IC50 = 40 μM) and protein phosphatase type 1 (PP1) (IC50 = 131 μM). Fostriecin is found in Streptomyces pulveraceous. Uses: Enzyme inhibitors. Synonyms: Fostriecin Sodium; Antibiotic CI 920 sodium salt; (6R)-5,6-Dihydro-6-[(1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-2H-pyran-2-one sodium salt. Grades: ≥98% by HPLC. CAS No. 87860-39-7. Molecular formula: C19H26O9PNa. Mole weight: 452.37. | |
| Fostroxacitabine Bralpamide | Fostroxacitabine Bralpamide is an antineoplastic drug. Synonyms: (2S)-pentan-2-yl N-[(S)-{[(2S,4S)-4-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-dioxolan-2-yl]methoxy}(4-bromophenoxy)phos-phoryl]-L-alaninate; L-Alanine, N-((((2S,4S)-4-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,3-dioxolan-2-yl)methoxy)(4-bromophenoxy)phosphinyl)-, (1S)-1-methylbutyl ester; (S)-pentan-2-yl ((S)-(((2S,4S)-4-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-dioxolan-2-yl)methoxy)(4-bromophenoxy)phosphoryl)-L-alaninate; MIV-818; MIV818; MIV 818; Troxacitabine nucleotide prodrug MIV-818. CAS No. 2129993-56-0. Molecular formula: C22H30BrN4O8P. Mole weight: 589.38. | |
| Fotagliptin benzoate | Fotagliptin benzoate is a Dipeptidyl Peptidase IV ( DPP-4 ) inhibitor ( IC 50 =2.27 nM). Fotagliptin benzoate displays great security in rat and dog. Fotagliptin benzoate can be used for Type 2 diabetes mellitus research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SAL067. CAS No. 1403496-40-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123377A. | |
| Fotagliptin impurity 1 | Fotagliptin impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-2-((3-(3-aminopiperidin-1-yl)-6-(hydroxymethyl)-5-oxo-1,2,4-triazin-4(5H)-yl)methyl)-4-fluorobenzonitrile. Molecular Formula: C17H19FN6O2. Mole Weight: 358.37. Catalog: APB06057. |  |
| Fotemustine | Fotemustine is a DNA-alkylating agent, with antitumor activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S10036. CAS No. 92118-27-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B0733. | |
| Fotemustine | Fotemustine is a chloroethylating nitrosourea with antineoplastic activity. Fotemustine alkylates guanine by forming chloroethyl adducts at the 6 position of guanine, resulting in N1-guanine and N3-cytosine cross linkages, inhibition of DNA synthesis, cell cycle arrest, and finally apoptosis. This agent is lipophilic and crosses the blood-brain barrier. Check for active clinical trials or closed clinical trials using this agent. Synonyms: Muphoran, S 10036. Grades: >98%. CAS No. 92118-27-9. Molecular formula: C9H19ClN3O5P. Mole weight: 315.691. | |
| Foti 10:1 | Foti 10:1. |  CA, FL & NJ |
| Fo-Ti Extract (Ratio) | Fo-Ti Extract (Ratio). Group: Others. Purity: 4:1~20:1. Fo-Ti Extract (Ratio). Cat No: EXTW-034. |  |
| Fo-Ti Root Powder (Polygonum Multiflorum) | Fo-Ti Root Powder (Polygonum Multiflorum). | CA, FL & NJ |
| Foundry Fluxes | Foundry Fluxes (blended, fused and granular). We offer a variety of products for diverse applications and maintain an extensive inventory at our warehouses to provide prompt shipment and on-time delivery to our customers. |  Worldwide |
| FOUNDRY RESIN | FOUNDRY RESIN. Group: Polymers. |  |
| Fowlicidin-2 | Fowlicidin-2, which is composed of 31 amino acids, is widely expressed in the majority of tissues in chickens and has an important role in innate immunity. | |
| Fowlicidin 3 | Fowlicidin-3 is an alpha-helical cationic host defense peptide with potent antibacterial and lipopolysaccharide-neutralizing activities. It is highly potent against a broad range of Gram-negative and Gram-positive bacteria in vitro, including antibiotic-resistant strains, with minimum inhibitory concentrations in the range 1-2 microM. | |
| Foxo1 Inhibitor, AS1842856 (5-Amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid) | A cell-permeable oxodihydroquinoline that preferentially inhibits the transcription activity of Forkhead box O family member Foxo1 (IC503nM) over that of the functionally related Foxo3a and Foxo4 (70%, 20%, and 3% inhibition, respectively, in HepG2-based reporter assays; [AS184256]0nM) via direct binding of the active Foxo1, but not the Ser256-phosphorylated / inactive form of Foxo1. Shown to inhibit gluconeogenesis in rat heptoma Fao cultures (IC50CnM against glucose production) in vitro and in liver of both non-diabetic and diabetic mice during a 26-hour fasting period (100mg/kg/8h p.o.) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??FN?O?, Molecular Weight: 347.4. US Biological Life Sciences. | Worldwide |
| FOXO4-DRI | FOXO4-DRI is a peptide acting as a specific FOXO4 blocker. It has been demonstrated to alleviate age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice. Grades: 95%. Molecular formula: C228H388N86O64. Mole weight: 5358.05. | |
| Foxy 5 | Foxy 5. Group: Biochemicals. Grades: Purified. CAS No. 881188-51-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Foxy-5 | A Wnt5a peptide mimetic. It has been undergoing clinical trials for the treatment of prostate cancer, colorectal cancer, metastatic colon cancer, metastatic breast cancer, and metastatic prostate cancer. Synonyms: Foxy 5; Foxy5; (2S) -2- [ [ (2S) -4-carboxy-2- [ [ (2R) -2- [ [2- [ [ (2S) -3-carboxy-2- [ [ (2S) -2-formamido-4-methylsulfanylbutanoyl] amino] propanoyl] amino] acetyl] amino] -3-sulfanylpropanoyl] amino] butanoyl] amino] -4-methylpentanoic acid. Grades: >95%. CAS No. 881188-51-8. Molecular formula: C26H42N6O12S2. Mole weight: 694.8. | |
| Foy 251 | FOY 251, an anti-proteolytic active metabolite Camostate (HY-13512), acts as a proteinase inhibitor. FOY 251 inhibits SARS-CoV-2 infection in cells assay. Group: Inhibitors. Alternative Names: 4-[[4-[ (Aminoiminomethyl) amino]benzoyl]oxy]-benzeneacetic Acid Monomethanesulfonat;FOY 251;4-(4-guanidinobenzoyloxy)phenylacetic acid; 4-[[4-[ (Aminoiminomethyl) amino]benzoyl]oxy]-benzeneacetic Acid Monomethanesulfonate. CAS No. 71079-09-9. Molecular formula: C17H19N3O7S. Mole weight: 409.413660 [g/mol]. Appearance: White Solid. Purity: 0.96. IUPACName: 2-[4-[4- (diaminomethylideneamino) benzoyl]oxyphenyl]acetic acid; methanesulfonic acid. Canonical SMILES: O=C (O)CC1=CC=C (OC (C2=CC=C (NC (N)=N)C=C2)=O)C=C1. CS (=O) (O)=O. Density: 1.36g/cm³. Catalog: ACM71079099. |  |
| FOY 251 | FOY 251 is a metabolite of camostat mesilate, and a proteinase inhibitor. Synonyms: FOY251; FOY-251; 4-(4-Guanidinobenzoyloxy)phenylacetic acid; 4-GBCE (methanesulfonate). CAS No. 71079-09-9. Molecular formula: C17H19N3O7S. Mole weight: 409.4. | |
| FOY 251 | A metabolite of Camostat. It is a pollen protease inhibitor for prevention and control of allergy. Group: Biochemicals. Alternative Names: 4-[[4-[ (Aminoiminomethyl) amino]benzoyl]oxy]-benzeneacetic Acid Monomethanesulfonate. Grades: Highly Purified. CAS No. 71079-09-9. Pack Sizes: 1mg. Molecular Formula: C??H??N?O?S, Molecular Weight: 409.41. US Biological Life Sciences. | Worldwide |
| FOY 251 Benzyl Ester Hydrochloride | Protected Camostat metabolite. Group: Biochemicals. Alternative Names: 4- [ [4- [ (Aminoiminomethyl) amino] benzoyl] oxy] benzeneacetic Acid Benzyl Ester Hydrochloride; 4- [ [4- [ (Aminoiminomethyl) amino] benzoyl] oxy] benzeneacetic Acid Phenylmethyl Ester Hydrochloride. Grades: Highly Purified. CAS No. 71079-12-4. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| FPA 124 | FPA 124 is an Akt/PKB inhibitor (IC50 = 100 nM) that inhibits cell proliferation in various cancer cell lines in vitro and decreases NF-κB activity and tumor load in vivo. Synonyms: FPA 124; FPA124; FPA-124; Akt Inhibitor XI; Dichloro[(2Z)-2-[(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazinecarbothioamide copper complex. CAS No. 902779-59-3. Molecular formula: C11H9Cl2CuN3O2S. Mole weight: 381.73. | |
| FP-biotin | FP-biotin. Group: Biochemicals. Alternative Names: [10- [ [5- [ [5- [ (3aS, 4S, 6aR) -Hexahydro-2-oxo-1H-thieno [3, 4-d] imidazol-4-yl] -1-oxopentyl] amino] pentyl] amino] -10-oxodecyl] phosphonofluoridic acid ethyl ester; 10-Fluoroethoxyphosphinyl -N-biotinamidopentyl decanamide . Grades: Highly Purified. CAS No. 259270-28-5. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C27H50FN4O5PS. US Biological Life Sciences. | Worldwide |
| FP-Biotin. | FP-Biotin. Group: Biochemicals. Alternative Names: [10- [ [5- [ [5- [ (3aS, 4S, 6aR) -Hexahydro-2-oxo-1H-thieno [3, 4-d] imidazol-4-yl] -1-oxopentyl] amino] pentyl] amino] -10-oxodecyl] phosphonofluoridic Acid Ethyl Ester; 10-Fluoroethoxyphosphinyl -N-biotinamidopentyl decanamide . Grades: Highly Purified. CAS No. 259270-28-5. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Fpg Protein from Escherichia coli, Recombinant | Fpg protein, a key enzyme in the DNA base excision repair pathway (BER), catalyses the excision of a broad spectrum of modified purines such as formamidopyrimidine (Fapy) and 8-oxoguanine (8-oxo-G). Fpg possess both DNA glycosylase activity that removes the mutated base and AP-lyase activity that releases ribose, leaving both 5'-and 3'-phosphorylated ends in the DNA. Several analytical methods based on Fpg protein activity in vitro were developed for detection and quantitation of oxidative damage to DNA mainly for FapyA, FapyG and 8-oxo-G. The fpg gene was cloned by Boiteux, et al. Fpg protein possess a zinc finger motif at its C-terminus (one zinc atom per molecule). ... Protein. Mole weight: mol wt 30.2 kDa (269 amino acids, predicted from the nucleotide sequence). Activity: >20 ,000 units/mg protein. Storage: -20°C. Form: buffered aqueous glycerol solution; Solution in 50% glycerol containing 50 mM potassium HEPES, pH 7.5, 1 mM DTT, 1 mM EDTA, and 200 mM NaCl. Source: E. coli. Species: Escherichia coli. Fapy-DNA glycosylase; deoxyribonucleate glycosidase; 2,6-diamino-4-hydroxy-5N-formamidopyrimidine-DNA glycosylase; 2,6-diamino-4-hydroxy-5 (N-methyl)formamidopyrimidine-DNA glycosylase; formamidopyrimidine-DNA glycosylase; DNA-formamidopyrimidine glycosidase; Fpg protein; DNA-formamidopyrimidine glycosylase; EC 3.2.2.23; 78783-53-6; | |
| FPH1 | FPH1 (BRD-6125) is a small molecule, which promotes expansion of iPS-derived hepatocytes. Synonyms: FPH 1; FPH-1; 2-(N-(5-Chloro-2-methylphenyl)methylsulfonamido)-N-(2,6-difluorophenyl)acetamide. Grades: >98%. CAS No. 708219-39-0. Molecular formula: C16H15ClF2N2O3S. Mole weight: 388.82. | |
| FPH2 | FPH2 induces of functional proliferation of primary human hepatocytes and may lead to the development of new therapeutics for liver diseases. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BRD-9424. CAS No. 957485-64-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12281. | |
| FPH2 | FPH2 is a small molecule, which promotes differentiation of iPS-derived hepatocytes. Synonyms: BRD-9424; BRD9424; BRD 9424; FPH2; FPH 2; FPH-2. Grades: >98%. CAS No. 957485-64-2. Molecular formula: C14H16ClN5O2S. Mole weight: 353.83. | |
| FPL 55712 | FPL 55712. Group: Biochemicals. Grades: Purified. CAS No. 40785-97-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| FPL 55712 | FPL 55712 is a leukotriene receptor antagonist that inhibits contraction of guinea pig trachealis induced by leukotrienes C4, D4, E4 and F4. Synonyms: FPL 55712; FPL55712; FPL-55712; 7-[3-(4-Acetyl-3-hydroxy-2-propylphenoxy)-2-hydroxypropoxy]-4-oxo-8-propyl-4H-1-benzopyran-2-carboxylic acid. Grades: ≥97% by HPLC. CAS No. 40785-97-5. Molecular formula: C27H30O9. Mole weight: 498.52. | |
| Fpl 64176 | Heterocyclic Organic Compound. CAS No. 120934-96-5. Molecular formula: C22H21NO3. Mole weight: 347.41. Purity: >99 %. Catalog: ACM120934965. | |
| FPL64176 | FPL64176, a nondihydropyridine compound, is a potent agonist of L-type Ca 2+ channels with an EC 50 value of 16 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 120934-96-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103307. | |
| FPL 64176 | FPL 64176. Group: Biochemicals. Grades: Purified. CAS No. 120934-96-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| FPL 64176 | FPL 64176 is a potent L-type Ca2+ channel activator (EC50 = 16 nM) displaying 40-fold potency against Bay K 8644 as a positive inotrope in guinea pig atria. Uses: Calcium channel agonists. Synonyms: FPL-64176; FPL 64176; FPL64176; 2,5-Dimethyl-4-[2-(phenylmethyl)benzoyl]-1H-pyrrole-3-carboxylic acid methyl ester; Methyl 4-(2-benzylbenzoyl)-2,5-dimethyl-1H-pyrrole-3-carboxylate. Grades: ≥99% by HPLC. CAS No. 120934-96-5. Molecular formula: C22H21NO3. Mole weight: 347.41. | |
| FPR A14 | FPR A14 is a formyl peptide receptor (FPR) agonist that potently activates neutrophils in vitro (EC50 = 42 and 630 nM for neutrophil chemotaxis and Ca2+ mobilization, respectively). Synonyms: AG 14; AG14; AG-14; 1,3-Benzodioxolane-5-carboxylic acid 4'-benzyloxy-3'-methoxybenzylidene hydrazide. Grades: ≥99% by HPLC. CAS No. 329691-12-5. Molecular formula: C23H20N2O5. Mole weight: 404.42. | |
| FPR A14 | FPR A14. Group: Biochemicals. Grades: Purified. CAS No. 329691-12-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| FPS-ZM1 | FPS-ZM1 is a high-affinity RAGE inhibitor with a K i of 25 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 945714-67-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-19370. | |
| FPS-ZM1 | FPS-ZM1 is a high-affinity RAGE-specific blocker that inhibits amyloid-β binding to the V domain of RAGE with Ki of 25 ± 5 nM in RAGE-transfected CHO cells. It binds exclusively to RAGE and inhibits β-secretase activity and Aβ production. It also suppresses microglia activation and the neuroinflammatory response in brain. It penetrates the blood-brain barrier and binds to RAGE, thus reducing the protein levels of various cytokines. It inhibits RAGE-mediated influx of circulating Aβ40 and Aβ42 into the brain. It is not toxic to mice and can easily cross the blood-brain barrier in vivo. It might be a novel therapeutic agent to treat AD patients. Uses: Fps-zm1 might be a novel therapeutic agent to treat ad patients. Synonyms: FPS-ZM1; FPS ZM1; FPSZM1; FPS-ZM 1; FPS ZM-1; FPSZM 1; N-benzyl-4-chloro-N-cyclohexylbenzaMide;4-Chloro-N-cyclohexyl-N-(phenylmethyl)benzamide. Grades: >98 %. CAS No. 945714-67-0. Molecular formula: C20H22ClNO. Mole weight: 327.85. | |
| FPT | FPT, a 2-Aminotetralin, is an efficacious partial agonist at 5-HT 1A R , a full agonist at 5-HT 1B R and 5-HT 1D R with EC 50 s of 39.3 nM, 1.2 nM, 0.5 nM, respectively. FPT is a weak agonist at 5-HT 7 R. FPT shows in vivo efficacy as an antiepileptic in Fmr1 knockout mice and has anxiolytic-like and prosocial effects in Fmr1 knockout mice and other mouse models [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2048491-06-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-160887. | |
| FP-TZTP | FP-TZTP. Group: Biochemicals. Alternative Names: 3-[4-[(3-Fluoropropyl)thio]-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridine. Grades: Highly Purified. CAS No. 424829-90-3. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C11H16FN3S2. US Biological Life Sciences. | Worldwide |
| FQI1 | FQI1 is a Late SV40 Factor ( LSF ) inhibitor. FQI1 inhibits cell proliferation, with IC 50 s of 3, 0.79, 6.3 μM for NIH/3T3, HeLa, A549 cells. FQI1 can be used for cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 599151-35-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-124429. | |
| FQI 1 | FQI 1 is a cell-permeable and reversible inhibitor of α-globin transcription factor CP2 (LSF; IC50 = 2.1 μM) and an antiproliferative. FQI 1 induces apoptosis in LSF-overexpressing cells, including Hepatocellular carcinoma (HCC cells). FQI 1 acts via inhibiting LSF-DNA binding. Uses: Antiproliferative. Synonyms: FQI 1; FQI1; FQI-1; 8-(2-ethoxyphenyl)-7,8-dihydro[1,3]dioxolo[4,5-g]quinolin-6(5H)-one; 8-(2-Ethoxy-phenyl)-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]quinolin-6-one. Grades: 99%. CAS No. 599151-35-6. Molecular formula: C18H17NO4. Mole weight: 311.33. | |
| FR 110302 | This active molecular is a potent 5-lipoxygenase inhibitor which was originated by Fujisawa company for treating asthma. No-Development was reported for asthma in Japan. Synonyms: FR 110302; FR110302; FR-110302. 2,2-dibutyl-1,2,3,4-tetrahydro-5-(2-quinolinylmethoxy)-1-Naphthalenol. Grades: 98%. CAS No. 119256-94-9. Molecular formula: C28H35NO2. Mole weight: 417.58. | |
| FR 113680 | FR 113680 is a novel tripeptide substance P antagonist with NK1 receptor selectivity originated by Fujisawa for the treatment of Asthma. But no development are reported yet. Uses: Asthma. Synonyms: FR 113680; FR113680; FR-113680; Ac-Thr-trp(cho)-phe-N-mebzl. Ac-Thr-trp(cho)-phe-N-mebzl;N-acetyl-L-threonyl-1-formyl-D-tryptophyl-N-methyl-N-(phenylmethyl)-L-Phenylalaninamide. Grades: 98%. CAS No. 126088-92-4. Molecular formula: C35H39N5O6. Mole weight: 625.72. | |
| FR 121196 | FR 121196 is a potential antidementia drug originated by Fujisawa. Mechanism of Action is not undefined. FR 121196 can ameliorate the impaired memory of rat in the Morris water maze. No development was reported for Cognition disorders in Japan. Uses: Cognition disorders. Synonyms: FR 121196; FR 121196; FR 121196. N-(4-acetylpiperazin-1-yl)-4-fluorobenzenesulfonamide. Grades: 98%. CAS No. 133920-65-7. Molecular formula: C12H16FN3O3S. Mole weight: 301.34. | |
| FR122047 | FR122047 (hydrochloride) is a selective and oral active inhibitor of COX-1 with an IC 50 of 28 nM. FR122047 hydrochloride has antiplatelet, analgesic and anti-inflammatory effects in vivo [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 130717-51-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103386. | |
| FR 122047 hydrochloride | FR 122047 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 130717-51-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| FR 122047 hydrochloride | FR-122047 is a selective cyclooxygenase-1 (COX-1) inhibitor with IC50 values is 0.028μM for COX-1 and 65 μM for COX-2. FR-122047 displays 2300 fold greater selectivity towards inhibition of COX-1 over COX-2. It shows analgesic, anti-platelet and anti-inflammatory properties. No development was reported for the treatment of Pain, Rheumatoid arthritis and Thrombosis. Uses: Pain; rheumatoid arthritis; thrombosis. Synonyms: FR 122047 hydrochloride;1-[[4,5-bis-(4-Methoxyphenyl)-2-thiazolyl]carbonyl]-4-methylpiperazine hydrochloride. Grades: >98 %. CAS No. 130717-51-0. Molecular formula: C23H25N3O3S.HCl. Mole weight: 459.99. | |
| FR122047 hydrochloride hydrate | FR122047 is a selective inhibitor of COX-1 with an IC50 value of 0.028 μM. Synonyms: 1-[[4,5-bis(4-methoxyphenyl)-2-thiazolyl]carbonyl]-4-methyl-piperazine, monohydrochloride, monohydrate. Grades: ≥98%. Molecular formula: C23H25N3O3S·HCl·H2O. Mole weight: 478. | |
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