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The side-chain ClTrt group can be removed with 1% TFA/ 5% TIS in DCM, enabling the side-chain hydroxyl group to be selectively modified whilst the derivative is attached to the solid support during Fmoc SPPS. Uses: Fmoc solid-phase peptide synthesis. Additional or Alternative Names: Fmoc-Tyr(2-ClTrt)-OH, N-α-Fmoc-O-2-chlorotrityl-L-tyrosine. Product Category: Amino Acids. CAS No. 350241-80-4. Molecular formula: C43H34ClNO5. Mole weight: 680.2. Product ID: ACM350241804-2. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Tyr(2-ClTrt)-OH
The side-chain ClTrt group can be removed with 1% TFA/ 5% TIS in DCM, enabling the side-chain hydroxyl group to be selectively modified whilst the derivative is attached to the solid support during Fmoc SPPS. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Tyr(2-ClTrt)-OH, N-α-Fmoc-O-2-chlorotrityl-L-tyrosine. Product Category: Amino Acids. CAS No. 350241-80-4. Mole weight: 680.19. Product ID: ACM350241804-1. Alfa Chemistry ISO 9001:2015 Certified.
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis.
Fmoc-Tyr(Me)-OH
Fmoc-Tyr(Me)-OH is a tyrosine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 77128-72-4. Pack Sizes: 10 g; 25 g; 100 g. Product ID: HY-W010943.
Fmoc-Tyr(Me)-OH
Standard building block for introduction of O-methyl-tyrosine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Tyr(Me)-OH, N-α-Fmoc-O-methyl-L-tyrosine. Product Category: Amino Acids. CAS No. 77128-72-4. Molecular formula: C25H23NO5. Mole weight: 417.45. Product ID: ACM77128724. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Tyr-OH. Group: Biochemicals. Alternative Names: N-Fmoc-L-tyrosine. Grades: Highly Purified. CAS No. 92954-90-0. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C24H21NO5. US Biological Life Sciences.
Worldwide
Fmoc-Tyr-OH
Fmoc-Tyr-OH is a tyrosine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 92954-90-0. Pack Sizes: 25 g; 100 g. Product ID: HY-W009003.
Fmoc-Tyr-OH
A useful derivative for the synthesis of phosphotyrosine peptides by the global Fmoc SPPS phosphorylation methodology. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Tyr-OH, N-α-Fmoc-L-tyrosine. Product Category: Amino Acids. CAS No. 92954-90-0. Molecular formula: C24H21NO5. Mole weight: 403.43. Product ID: ACM92954900. Alfa Chemistry ISO 9001:2015 Certified. Categories: (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(4-hydroxyphenyl)propanoic acid.
Fmoc-Tyr-OH-15N
Fmoc-Tyr-OH-15N. Uses: Peptide synthesis. Additional or Alternative Names: N-(9-Fluorenylmethoxycarbonyl)-L-tyrosine-15N, L-Tyrosine-15N, N-Fmoc derivative. Product Category: Amino Acids. CAS No. 125700-34-7. Mole weight: 404.42. Canonical SMILES: OC(=O)[C@H](Cc1ccc(O)cc1)[15NH]C(=O)OCC2c3ccccc3-c4ccccc24. Product ID: ACM125700347-1. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Tyr-OH-[15N]
Fmoc-Tyr-OH-[15N]. Synonyms: N-(9-Fluorenylmethoxycarbonyl)-L-tyrosine-15N; Fmoc-Tyr-OH-15N. Grade: 97% by CP; 98% atom 15N. CAS No. 125700-34-7. Molecular formula: C24H21[15N]O5. Mole weight: 404.42.
Fmoc-tyr-ome
Fmoc-tyr-ome. Uses: Designed for use in research and industrial production. Additional or Alternative Names: FMOC-TYR-OME;METHYL D-AMINOLEVULINATE HYDROCHLORIDE. Product Category: Heterocyclic Organic Compound. CAS No. 82911-79-3. Molecular formula: C25H23NO5. Product ID: ACM82911793. Alfa Chemistry ISO 9001:2015 Certified. Categories: (S)-Methyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-hydroxyphenyl)propanoate.
A useful derivative for the synthesis of phosphotyrosine peptides by Fmoc SPPS. Pyrophosphate formation has been noted in peptides containing adjacent Tyr(PO3H2) residues. An evaluation of the optimal coupling conditions for introduction of this residue has been made. Uses: Peptide synthesis. Additional or Alternative Names: Nα-Fmoc-O-phospho-L-tyrosine, N-α-Fmoc-O-phospho-L-tyrosine. Product Category: Amino Acids. CAS No. 147762-53-6. Mole weight: 483.41. Canonical SMILES: OC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCC2c3ccccc3-c4ccccc24. Product ID: ACM147762536-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-[4-(phosphonooxy)phenyl]propanoic acid.
An excellent building block for the preparation of phosphotyrosine-containing peptides by Fmoc SPPS. This derivative can be introduced using standard activation methods, such as PyBOPand TBTU. Using this reagent, even peptides containing multiple phosphorylation sites have been prepared efficiently by standard Fmoc SPPS methods. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Tyr(PO(OBzl)OH)-OH, N-α-Fmoc-O-benzyl-L-phosphotyrosine. Product Category: Amino Acids. CAS No. 191348-16-0. Molecular formula: C31H28NO8P. Mole weight: 573.53. Product ID: ACM191348160-1. Alfa Chemistry ISO 9001:2015 Certified.
A novel derivative for the synthesis of sulfotyrosine-containing peptides by Fmoc SPPS. The sulfate neopentyl group is stable to TFA, and thus protects the sulfotyrosine residue from degradation during the cleavage reaction, but is easily cleaved post-cleavage by treatment of the peptide with aqueous ammonium acetate. Group: Biochemicals. Grades: Highly Purified. CAS No. 878408-63-0. Pack Sizes: 1g. Molecular Formula: C??H??NO?S, Enantiomeric. US Biological Life Sciences.
Worldwide
Fmoc-Tyr(SO3nP)-OH
A novel derivative for the synthesis of sulfotyrosine-containing peptides by Fmoc SPPS. The sulfate neopentyl group is stable to TFA, and thus protects the sulfotyrosine residue from degradation during the cleavage reaction, but is easily cleaved post-cleavage by treatment of the peptide with aqueous ammonium acetate. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Tyr(SO3nP)-OH, N-Fmoc-O-(2,2 dimethylpropylsulfo)-L-tyrosine. Product Category: Amino Acids. CAS No. 878408-63-0. Molecular formula: C29H31NO8S. Mole weight: 553.62. IUPACName: (2S)-3-[4-(2,2-dimethylpropoxysulfonyloxy)phenyl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid. Canonical SMILES: CC(C)(C)COS(=O)(=O)OC1=CC=C(C=C1)CC(C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24. Product ID: ACM878408630. Alfa Chemistry ISO 9001:2015 Certified. Categories: Fmoc-Tyr(SO2(ONeopentyl))-OH.
Fmoc-Tyr(tBu)-2-chlorotrityl resin
Pre-loaded resins for solid phase peptide and organic synthesis. Synonyms: Fmoc-O-tert-butyl-L-tyrosine-2-chlorotrityl resin.
Wang resins are the standard supports for the preparation of peptide acids by the Fmoc batch solid phase synthesis strategy. Fmoc amino acids are pre-loaded to Wang resins so that that epimerization and dipeptide formation are minimized. Synonyms: Fmoc-Tyr(tBu)-Wang-PEG Resin; N-α-(9-Fluorenylmethoxycarbonyl)-O-(t-butyl)-L-tyrosine p-methoxybenzyl alcohol polyethyleneglycol resin.
Fmoc-Tyr(tBu)-OH is a tyrosine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 71989-38-3. Pack Sizes: 25 g; 100 g; 500 g. Product ID: HY-W008016.
Fmoc-Tyr(tBu)-OH
Fmoc-Tyr(tBu)-OH. Group: Biochemicals. Grades: Highly Purified. CAS No. 71989-38-3. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C28H29NO5. US Biological Life Sciences.
Worldwide
Fmoc-Tyr(tBu)-OH
High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities. Standard building block for introduction of tyrosine amino-acid residues by Fmoc SPPS. Uses: Fmoc-tyr(tbu)-oh novabiochem®. cas 71989-38-3, molar mass 459.55 g/mol. Additional or Alternative Names: Fmoc-Tyr(tBu)-OH, N-α-Fmoc-O-t.-butyl-L-tyrosine. Product Category: Amino Acids. CAS No. 71989-38-3. Molecular formula: C28H29NO5. Mole weight: 459.53. Purity: Peak Area by HPLC ≥95%. Product ID: ACM71989383. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Tyr(tBu)-OH, 98%min.
Fmoc-Tyr(tBu)-OH, 98%min.. CAS No: 71989-38-3
Sarchem Laboratories New Jersey NJ
Fmoc-Tyr(tBu)-OPfp
Pre-formed pentafluorophenyl ester for coupling of tyrosine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Tyr(tBu)-OPfp, N-α-Fmoc-O-t.-butyl-L-tyrosine pentafluorophenyl ester. Product Category: Amino Acids. CAS No. 86060-93-7. Mole weight: 625.58. Product ID: ACM86060937-1. Alfa Chemistry ISO 9001:2015 Certified.
This pseudoproline dipeptide is undoubtedly the most effective and simplest to use tool for overcoming aggregation and enhancing peptide quality in Fmoc SPPS for peptide containing the Tyr-Ser dipeptide motif. It consists of a dipeptide in which the serine residue has been reversibly protected as a structure-breaking proline-like TFA-labile oxazolidine. The reason the pseudoproline residue is introduced as a dipeptide is because it avoids the need to acylate the hindered oxazolidine nitrogen. This has the added advantage of extending the peptide chain by two residues in one step. The serine residue is regenerated during the normal TFA-mediated cleavage reaction. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Tyr(tBu)-Ser(psiMe,Mepro)-OH. Product Category: Amino Acids. CAS No. 878797-09-2. Mole weight: 586.67. Product ID: ACM878797092. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Tyr(tBu)-Ser[Psi(Me,Me)Pro]-OH 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 878797-09-2. Pack Sizes: 1g, 5g, 10g. US Biological Life Sciences.
Worldwide
Fmoc-Tyr(tBu)-Thr(psiMe,Mepro)-OH
This pseudoproline dipeptide is undoubtedly the most effective and simplest to use tool for overcoming aggregation and enhancing peptide quality in Fmoc SPPS for peptide containing the Tyr-Thr dipeptide motif. It consists of a dipeptide in which the threonine residue has been reversibly protected as a structure-breaking proline-like TFA-labile oxazolidine. The reason the pseudoproline residue is introduced as a dipeptide is because it avoids the need to acylate the hindered oxazolidine nitrogen. This has the added advantage of extending the peptide chain by two residues in one step. The threonine residue is regenerated during the normal TFA-mediated cleavage reaction. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Tyr(tBu)-Thr(psiMe,Mepro)-OH. Product Category: Amino Acids. CAS No. 920519-31-9. Mole weight: 600.7. Product ID: ACM920519319-1. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Val-Ala-OH is a widely used cleavable peptide linker that can conveniently serve as a building block for the careful construction of peptide-directed therapeutics and pharmaceuticals. Its multifaceted nature holds great promise in combating a range of diseases, including but not limited to neoplastic diseases, autoimmune diseases, and potential infections. Synonyms: (S)-2-((S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-methylbutanamido)propanoic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl-L-alanine. Grade: ≥ 95%. CAS No. 150114-97-9. Molecular formula: C23H26N2O5. Mole weight: 410.46.
Fmoc-Val-Ala-Osu
Fmoc-Val-Ala-Osu. Synonyms: Fmoc Val Ala Osu. Molecular formula: C28H29N3O9. Mole weight: 551.54.
Fmoc-Val-Ala-PAB-OH
Fmoc-Val-Ala-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: Fmoc-Val-Ala-PAB; (9H-Fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate. Grade: >98.0%(HPLC)(N). CAS No. 1394238-91-5. Molecular formula: C30H33N3O5. Mole weight: 515.60.
Fmoc-Val-Ala-PAB-PNP
Fmoc-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1394238-92-6. Pack Sizes: 100 mg; 250 mg. Product ID: HY-136136.
Fmoc-Val-Alko-PEG Resin
Wang resins are the standard supports for the preparation of peptide acids by the Fmoc batch solid phase synthesis strategy. Fmoc amino acids are pre-loaded to Wang resins so that that epimerization and dipeptide formation are minimized. Synonyms: Fmoc-Val-Wang-PEG Resin; N-α-(9-Fluorenylmethoxycarbonyl)-L-valine p-methoxybenzyl alcohol polyethyleneglycol resin.
Fmoc-Val-Cit-OH
Fmoc-Val-Cit-OH. Synonyms: Fmoc Val Cit OH; (S)-2-((S)-2-((((9H-Fluoren-9-YL)methoxy)carbonyl)amino)-3-methylbutanamido)-5-ureidopentanoic acid. CAS No. 159858-21-6. Molecular formula: C26H32N4O6. Mole weight: 496.6.
Fmoc-Val-Cit-PAB
Fmoc-Val-Cit-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: Fmoc-Val-Cit-PAB-OH; L-Ornithinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-. CAS No. 159858-22-7. Molecular formula: C33H39N5O6. Mole weight: 601.70.
Fmoc-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Val-Cit-PAB-PNP has superior plasma stability comparable to that of non-cleavable linkers[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 863971-53-3. Pack Sizes: 50 mg; 100 mg; 250 mg; 1 g; 5 g; 10 g. Product ID: HY-41189.
High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities. Standard building block for introduction of valine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Val-OH, N-α-Fmoc-L-valine. Product Category: Amino Acids. CAS No. 68858-20-8. Molecular formula: C20H21NO4. Mole weight: 339.39. Product ID: ACM68858208. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Val-OH
Fmoc-Val-OH. Group: Biochemicals. Alternative Names: N- (9-Fluorenyl methoxycarbonyl ) -L-valine. Grades: Highly Purified. CAS No. 68858-20-8. Pack Sizes: 100g, 250g, 500g, 1kg, 2kg. Molecular Formula: C20H21NO4. US Biological Life Sciences.
Worldwide
FMOC-VAL-OH
FMOC-VAL-OH. CAS No: 68858-20-8
Sarchem Laboratories New Jersey NJ
Fmoc-Val-OH-1-13C
Fmoc-Val-OH-1-13C. Uses: Peptide synthesis. Additional or Alternative Names: N-(9-Fluorenylmethoxycarbonyl)-L-valine-1-13C, L-Valine-1-13C, N-Fmoc derivative. Product Category: Amino Acids. CAS No. 286460-74-0. Molecular formula: (CH3)2CHCH(NH-Fmoc)13CO2H. Mole weight: 340.38. Canonical SMILES: CC(C)[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)[13C](O)=O. Product ID: ACM286460740-2. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Val-OH-15N
Fmoc-Val-OH-15N. Uses: Peptide synthesis. Additional or Alternative Names: N-(9-Fluorenylmethoxycarbonyl)-L-valine-15N, L-Valine-15N, N-Fmoc derivative. Product Category: Amino Acids. CAS No. 125700-35-8. Molecular formula: (CH3)2CHCH(15NH-Fmoc)CO2H. Mole weight: 340.38. Canonical SMILES: CC(C)[C@H]([15NH]C(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O. Product ID: ACM125700358-1. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Val-OH-15N
98 atom % 15N. Group: Fluorescence/luminescence spectroscopy.