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Fmoc-selenomethionine can be introduced under standard conditions. Any selenoxide formed during synthesis can be easily reduced back to selenide by treatment with β-mercaptoethanol. Introduction of selenium can help facilitate solid phase and solution structural determination and the study of peptide-protein interactions. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-selenomethionine, N-Fmoc-L-amino-4-(methylselanyl)butanoic acid. Product Category: Amino Acids. CAS No. 1217852-49-7. Mole weight: 418.35. Product ID: ACM1217852497-1. Alfa Chemistry ISO 9001:2015 Certified.
The O-glycosidic linkage and the O-acetyl protection in this building block is stable to both piperidine and TFA , making it completely compatible with standard protocols in Fmoc solid phase peptide synthesis. Removal of the acetyl protecting groups is best carried out by treatment of the peptidyl resin with methanolic ammonia prior to cleavage. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Ser(Ac3AcNH-α-Gal)-OH, N-α-Fmoc-O-(2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-α-D-galactopyranosyl)-L-serine. Product Category: Amino Acids. CAS No. 120173-57-1. Mole weight: 656.63. Product ID: ACM120173571-1. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Ser(Ac3AcNH-α-Glc)-OH
Fmoc-Ser(Ac3AcNH-α-Glc)-OH is a glycosylated serine derivative used in the synthesis of glycopeptides. The Fmoc group protects the amino group of serine, while the attached α-glucose molecule, modified with three acetyl groups and an N-acetyl group, provides a specific glycosylation pattern. This compound is valuable in biochemical and pharmaceutical research for creating glycosylated peptides, which are important for studying protein-carbohydrate interactions, enhancing peptide stability, and improving therapeutic properties. Synonyms: N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-α-D-glucopyranosyl]-L-serine; Fmoc-Ser(GlcNAc(Ac)-α-D)-OH; (Fmoc-L-Ser(α-D-GlcNAc(Ac)3)-OH); N-Fmoc-O-(2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-α-D-glucopyranosyl)-L-serine; N-(((9H-fluoren-9-yl)methoxy)carbonyl)-O-((2S,3R,4R,5S,6R)-3-acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl)-L-serine. Grade: ≥95%. CAS No. 172325-15-4. Molecular formula: C32H36N2O13. Mole weight: 656.64.
Fmoc-Ser(Ac3AcNH-ß-Glc)-OH
The O-glycosidic linkage and the O-acetyl protection in this building block are stable to both piperidine and TFA, making it completely compatible with standard protocols in Fmoc solid phase peptide synthesis. Removal of the acetyl-protecting groups is best carried out by treatment of the peptidyl resin with methanolic ammonia prior to cleavage. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Ser(Ac3AcNH-ß-Glc)-OH, N-α-Fmoc-O-(2-Acetamido-2-deoxy-tri-O-acetyl-β-D-glucopyranosyl)-L-serine. Product Category: Amino Acids. CAS No. 160067-63-0. Molecular formula: C32H36N2O13. Mole weight: 656.63. Product ID: ACM160067630. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-ser(bzl)-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-serine phenylmethyl ester;Fmoc-Ser(Bzl)-OH. Product Category: Heterocyclic Organic Compound. CAS No. 73724-46-6. Molecular formula: C25H23NO5. Mole weight: 417.45. Product ID: ACM73724466. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Ser-OH is a serine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 73724-45-5. Pack Sizes: 100 g; 500 g. Product ID: HY-W007720.
Fmoc-Ser-OH
Useful derivative for the synthesis of phosphoserine peptides by the Fmoc SPPS global phosphorylation methodology. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Ser-OH, N-α-Fmoc-L-serine. Product Category: Amino Acids. CAS No. 73724-45-5. Mole weight: 327.33. Product ID: ACM73724455-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-hydroxypropanoic acid.
Fmoc-Ser(OtBu)-Asp(OtBu)-Tyr(OtBu)-Ser(OtBu)-OH is a protected tetrapeptide used in peptide synthesis. The Fmoc (Fluorenylmethyloxycarbonyl) group protects the N-terminus of the first serine (Ser) residue, preventing it from participating in premature reactions. The side chains of serine (Ser), aspartic acid (Asp), and tyrosine (Tyr) residues are protected by OtBu (tert-butyl) groups, which shield the hydroxyl and carboxyl groups during the synthesis process. The final Ser residue has a free carboxyl group at the C-terminus, indicated by -OH, which allows for further coupling or modifications. This peptide is designed to incorporate serine, aspartic acid, and tyrosine into peptide chains, with the protective groups ensuring precise and efficient synthesis. Synonyms: SDYS; N-((S)-2-((S)-2-((S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(tert-butoxy)propanamido)-4-(tert-butoxy)-4-oxobutanamido)-3-(4-(tert-butoxy)phenyl)propanoyl)-O-(tert-butyl)-L-serine; Fmoc-Ser(tBu)-Asp(tBu)-Tyr(tBu)-Ser(tBu)-OH. Grade: ≥97%. Molecular formula: C50H68N4O12. Mole weight: 917.11.
Fmoc-Ser(PO(OBzl)OH)-OH
An excellent building block for the preparation of phosphoserine-containing peptides by Fmoc SPPS. This derivative can be introduced using standard activation methods, such as PyBOPand TBTU. The monoprotected phosphoserine residue once incorporated is stable to piperidine. Using this reagent, even peptides containing multiple phosphorylation sites can be prepared efficiently by standard Fmoc SPPS methods. Applications of this derivative include the preparation of phospholamban , a 52 residue peptide containing both phosphoserine and phosphothreonine, and human salivary statherin, a 42 residue phosphoserine peptide ; for other examples see references.Recently, β-piperidinylalanine formation has been shown to occur during Fmoc deprotection of N-terminal Ser(PO(OBzl)OH), particularly under microwave conditions. This side reaction can be eliminated by using cyclohexylamine or DBU just for this Fmoc deprotection step. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Ser(PO(OBzl)OH)-OH, N-α-Fmoc-O-benzyl-L-phosphoserine. Product Category: Amino Acids. CAS No. 158171-14-3. Molecular formula: C25H24NO8P. Mole weight: 497.43. Product ID: ACM158171143-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[hydroxy(phenylmethoxy)phosphoryl]oxypropanoic acid.
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis.
Fmoc-Ser(tBu)-Aib-OH
Fmoc-Ser(tBu)-Aib-OH is commonly used in solid-phase peptide synthesis (SPPS) as a building block for peptide chains. CAS No. 135875-33-1. Molecular formula: C26H32N2O6. Mole weight: 468.55.
Fmoc-Ser(tBu)-Alko-PEG Resin
Wang resins are the standard supports for the preparation of peptide acids by the Fmoc batch solid phase synthesis strategy. Fmoc amino acids are pre-loaded to Wang resins so that that epimerization and dipeptide formation are minimized. Synonyms: Fmoc-Ser(tBu)-Wang-PEG Resin; N-α-(9-Fluorenylmethoxycarbonyl)-O-(t-butyl)-L-serine p-methoxybenzyl alcohol polyethyleneglycol resin.
High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities. Standard building block for introduction of serine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Ser(tBu)-OH, N-α-Fmoc-O-t.-butyl-L-serine. Product Category: Amino Acids. CAS No. 71989-33-8. Molecular formula: C22H25NO5. Mole weight: 383.44. Product ID: ACM71989338-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: DTXSID601231254.
Fmoc-Ser(tBu)-OH
Fmoc-Ser(tBu)-OH is a serine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 71989-33-8. Pack Sizes: 100 g; 500 g. Product ID: HY-W007941.
Fmoc-Ser(tBu)-OH
Fmoc-Ser(tBu)-OH. Group: Biochemicals. Alternative Names: Fmoc-O-tert-butyl-L-serine; N- (9-Fluorenyl methoxycarbonyl ) -O-tert-butyl -L-serine; Fmoc-L-Ser(tBu)-OH. Grades: Highly Purified. CAS No. 71989-33-8. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C22H25NO5. US Biological Life Sciences.
Fmoc-Ser(tBu)-Ser(psi(Me,Me)pro)-OH is a dipeptide. Uses: Scientific research. Group: Peptides. CAS No. 1000164-43-1. Pack Sizes: 250 mg; 500 mg; 1 g. Product ID: HY-P2407.
Fmoc-Ser(tBu)-Ser[Psi(Me,Me)Pro]-OH
Fmoc-Ser(tBu)-Ser[Psi(Me,Me)Pro]-OH is used as a reactant in the synthesis of peptides and proteins. Synonyms: Fmoc-Ser(tBu)-Ser[Ψ(Me,Me)Pro]-OH; (S)-3-[Nα-(9-Fluorenylmethyloxycarbonyl)-O-tert-butyl-L-serinyl]-2,2-dimethyloxazolidine-4-carboxylic acid; Fmoc-Ser(Tbu)-Ser(Psime,Mepro)-OH; (4S)-3-[(2S)-3-(tert-butoxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoyl]-2,2-dimethyl-1,3-oxazolidine-4-carboxylic acid; Fmoc-L-Ser(tBu)-L-Ser(Psi(Me,Me)pro)-OH; (S)-3-((S)-2-(((E)-((9H-fluoren-9-yl)methoxy)(hydroxy)methylene)amino)-3-(tert-butoxy)propanoyl)-2,2-dimethyloxazolidine-4-carboxylic acid. Grade: ≥ 98.5% (HPLC). CAS No. 1000164-43-1. Molecular formula: C28H34N2O7. Mole weight: 510.58.
Fmoc-Ser(tBu)-Ser[Psi(Me,Me)Pro]-OH ≥98.5% (HPLC)
Fmoc-Ser(tBu)-Ser[Psi(Me,Me)Pro]-OH ≥98.5% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 1000164-43-1. Pack Sizes: 1g, 5g, 10g. US Biological Life Sciences.
Worldwide
Fmoc-Ser(tBu)-Ser(tBu)-OH
Fmoc-Ser(tBu)-Ser(tBu)-OH is a protected dipeptide used in peptide synthesis. It features an Fmoc (Fluorenylmethyloxycarbonyl) group at the N-terminus, which protects the amino group during synthesis. Each Ser (Serine) residue is protected by a tBu (tert-butyl) group at the hydroxyl side chain, preventing unwanted side reactions. The -OH at the C-terminus indicates a free carboxyl group, allowing the dipeptide to be coupled with other amino acids. This compound is used to incorporate serine residues into peptides while maintaining the integrity of the hydroxyl groups for selective deprotection later in the synthesis process. Synonyms: N-(Fluorenylmethoxycarbonyl)-O-tert-butyl-L-seryl-O-tert-butyl-L-serine; (S)-2-((S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(tert-butoxy)propanamido)-3-(tert-butoxy)propanoic acid; L-Serine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-seryl-O-(1,1-dimethylethyl)-; L-Serine, O-(1,1-dimethylethyl)-N-[O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-seryl]-; N-(N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyl)-L-seryl)-O-(tert-butyl)-L-serine; O-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-seryl-O-(1,1-dimethylethyl)-L-serine; PSM-SS-1; SS; Fmoc-Ser(OtBu)-Ser(OtBu)-OH. Grade: ≥95%. CAS No. 110098-50-5. Molecular formula: C29H38N2O7. Mole weight: 526.62.
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis.
Fmoc-Ser(Trt)-OH
Fmoc-Ser(Trt)-OH is a serine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 111061-56-4. Pack Sizes: 5 g; 10 g. Product ID: HY-W010734.
Fmoc-Ser(Trt)-Wang Resin
Fmoc-Ser(Trt)-Wang Resin. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
Fmoc-S-ethyl-L-cysteine
Fmoc-S-ethyl-L-cysteine. Group: Biochemicals. Alternative Names: Fmoc-L-Cys(Et)-OH. Grades: Highly Purified. CAS No. 200354-34-3. Pack Sizes: 1g, 2g, 5g, 10g, 25g. US Biological Life Sciences.
Fmoc-ß-(2-pyridyl)-Ala-OH 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
FMOC-ß-ALA-OH
Standard building block for introduction of β-alanine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Additional or Alternative Names: FMOC-ß-ALA-OH, N-β-Fmoc-β-alanine. Product Category: Amino Acids. CAS No. 35737-10-1. Molecular formula: C18H17NO4. Mole weight: 311.33. Product ID: ACM35737101. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-(S,S)-[Pro-Leu]-spirolactame
Fmoc-(S,S)-[Pro-Leu]-spirolactame. Group: Biochemicals. Grades: Highly Purified. CAS No. 129605-53-4. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. US Biological Life Sciences.
Worldwide
Fmoc-(S,S)-[Pro-Leu]-spirolactame ≥97% (HPLC)
Fmoc-(S,S)-[Pro-Leu]-spirolactame ≥97% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences.
Worldwide
Fmoc-S-sulfo-L-cysteine disodium
A useful cysteine derivative for solid-phase synthesis by the Fmoc-strategy. Synonyms: Fmoc-L-Cys(SO3H)-OH disodium salt; FMOC-S-SULFO-L-CYSTEINE DISODIUM; Fmoc-S-sulfo-L-cysteine disodium salt. Grade: ≥ 99.8% (HPLC, Chiral purity). CAS No. 163558-30-3. Molecular formula: C18H15NNa2O7S2. Mole weight: 467.43.
Fmoc-S-sulfo-L-cysteine disodium 98+% (HPLC)
Fmoc-S-sulfo-L-cysteine disodium 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 163558-30-3. Pack Sizes: 1g, 5g. US Biological Life Sciences.