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This "polymeric benzaldehyde" reversibly binds e.g. amines or diols. Uses: The resin has been used to prepare 2,5-disubstituted tetrahydrofurans via electrophilic rearrangement of isoxazolines produced by the [3+2] addition of nitrile oxides to resin-bound alkenes and in the synthesis of new resins for chemical ligation and cyclization of unprotected peptides. Group: Formyl polystyrene resins. Pack Sizes: 5g, 25g, 100g.
formyltetrahydrofolate deformylase
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is 10-formyltetrahydrofolate amidohydrolase. This enzyme participates in glyoxylate and dicarboxylate metabolism and one carbon pool by folate. Group: Enzymes. Enzyme Commission Number: EC 3.5.1.10. CAS No. 9025-8-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4378; formyltetrahydrofolate deformylase; EC 3.5.1.10; 9025-08-5. Cat No: EXWM-4378.
formyltetrahydrofolate dehydrogenase
This enzyme belongs to the family of oxidoreductases, to be specific those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 10-formyltetrahydrofolate:NADP+ oxidoreductase. Other names in common use include 10-formyl tetrahydrofolate:NADP oxidoreductase, 10-formyl-H2PtGlu:NADP oxidoreductase, 10-formyl-H4folate dehydrogenase, N10-formyltetrahydrofolate dehydrogenase, and 10-formyltetrahydrofolate dehydrogenase. This enzyme participates in one carbon pool by folate. Group: Enzymes. Synonyms: 10-formyl tetrahydrofolate:NADP oxidoreductase; 10-formyl-H2PtGlu:NADP oxidoreductase 10-formyl-H4folate dehydrogenase; N10-formyltetrahydrofolate dehydrogenase 10-formyltetrahydrofolate dehydrogenase. Enzyme Commission Number: EC 1.5.1.6. CAS No. 37256-25-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1533; formyltetrahydrofolate dehydrogenase; EC 1.5.1.6; 37256-25-0; 10-formyl tetrahydrofolate:NADP oxidoreductase; 10-formyl-H2PtGlu:NADP oxidoreductase 10-formyl-H4folate dehydrogenase; N10-formyltetrahydrofolate dehydrogenase 10-formyltetrahydrofolate dehydrogenase. Cat No: EXWM-1533.
Forodesine, also known as BCX-1777, is the hydrochloride salt of the synthetic high-affinity transition-state analogue forodesine. Forodesine binds preferentially to and inhibits purine nucleotide phosphorylase (PNP), resulting in the accumulation of deoxyguanosine triphosphate and the subsequent inhibition of the enzyme ribonucleoside diphosphate reductase and DNA synthesis. This agent selectively causes apoptosis in stimulated or malignant T-lymphocytes. A transition state analogue is a substrate designed to mimic the properties or the geometry of the transition state of reaction. Synonyms: Immucillin-H hydrochloride; Forodesine. Grades: 98%. CAS No. 209799-67-7. Molecular formula: C11H14N4O4. Mole weight: 266.25.
Forodesine
Forodesine (BCX-1777) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC 50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine is a potent human lymphocyte proliferation inhibitor. Forodesine could induce apoptosis in leukemic cells by increasing the dGTP levels [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BCX-1777; Immucillin-H. CAS No. 209799-67-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-16210.
FORODESINE
Forodesine (BCX-1777) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine is a potent human lymphocyte proliferation inhibitor. Forodesine could induce apoptosis in leukemic cells by increasing the dGTP levels. Group: Inhibitors. CAS No. 209799-67-7. Molecular formula: C11H14N4O4. Mole weight: 266.26. Appearance: White to Yellow Solid. Purity: 0.95. Canonical SMILES: O=C1C (NC=C2[C@@H]3N[C@H] (CO)[C@@H] (O)[C@H]3O)=C2NC=N1. Catalog: ACM209799677.
Forodesine hydrochloride
Forodesine hydrochloride (BCX-1777 hydrochloride) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC 50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine hydrochloride is a potent human lymphocyte proliferation inhibitor. Forodesine hydrochloride could induce apoptosis in leukemic cells by increasing the dGTP levels [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BCX-1777 hydrochloride; Immucillin-H hydrochloride. CAS No. 284490-13-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-16209.
Forodesine hydrochloride
Forodesine hydrochloride is the hydrochloride salt of Forodesine. Forodesine, also called as BCX-1777 or Immucillin-H, is an orally bioavailable inhibior of mammalian purine nucleoside phosphorylase (PNP). Forodesine is undergoing a phase II trial to trea. Synonyms: 7-[(2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-2-yl]-1,5-dihydropyrrolo[3,2-d]pyrimidin-4-one;hydrochloride1-(9-deazahypoxanthin-9-yl)-1,4-dideoxy-1,4-iminoribitolBCX-1777; BCX1777BCX1777forodesineImmH cpdimmucillin Himmucillin-H. CAS No. 284490-13-7. Molecular formula: C11H15ClN4O4. Mole weight: 302.715.
FORON BRILLIANT PINK E-FG
Heterocyclic Organic Compound. Alternative Names: FORON BRILLIANT PINK E-FG;C.I.Disperse Red 55;Celliton Fast Pink RYL;Kayalon Polyester Pink 2BL-E;Miketon Polyester Pink BL;Terasil Brilliant Pink FG. CAS No. 12223-36-8. Molecular formula: C16H13NO5. Purity: 0.96. IUPACName: 1-amino-4-hydroxy-2-(2-hydroxyethoxy)anthracene-9,10-dione. Canonical SMILES: C1=CC=C2C (=C1)C (=O)C3=C (C2=O)C (=C (C=C3O)OCCO)N. ECNumber: 241-819-5. Catalog: ACM12223368.
Forosamine
Forosamine is an indispensable compound crucial in the R&D of antifungal and antibacterial drugs, used for studying an array of drug-resistant fungal infections including Candida and Aspergillus, while also combatting bacterial infections instigated by Staphylococcus aureus and Streptococcus pneumoniae. Synonyms: 4-Dimethylamino-2,3,4,6-tetradeoxy-D-erythro-hexose; 2,3,4,6-tetradeoxy-4-dimethylamino-D-erythro-hexosee; Hexanal, 4-(dimethylamino)-5-hydroxy-, (4S,5R)-; Hexanal, 4-(dimethylamino)-5-hydroxy-, [R-(R*,S*)]-. Grades: ≥95%. CAS No. 18423-27-3. Molecular formula: C8H17NO2. Mole weight: 159.23.
Forskolin - Product ID: NST-10-164. Category: Terpenes. Alternative Names: (-)-Forskolin, Coleonol, Colforsin, ForsLean. Purity: 98%. Test method: HPLC. CAS No. 66575-29-9. Pack Sizes: 0,05g, 0,1g, 0,25g, 0,5g. Appearance: White powder. Molecular formula: C22H34O7. Mole weight: 410.5. Storage: +2 +8 °C.
Forskolin
Forskolin (Coleonol) is a potent adenylate cyclase activator with an IC 50 of 41 nM and an EC 50 of 0.5 μM for type I adenylyl cyclase [1]. Forskolin is also an inducer of intracellular cAMP formation [2]. Forskolin induces differentiation of various cell types and activates pregnane X receptor (PXR) and FXR [3]. Forskolin exerts a inotropic effect on the heart, and has platelet antiaggregatory and antihypertensive actions. Forskolin also induces autophagy [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Coleonol; Colforsin; HL 362. CAS No. 66575-29-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-15371.
Forskolin
Forskolin is a diterpene isolated from Coleus forskohlii, possessing vasodilating and cardiostimulatory properties. Forskolin resensitizes cell receptors by activating the enzyme adenylyl cyclase and increasing the intracellular levels of cAMP. Group: Biochemicals. Alternative Names: (3R, 4aR, 5S, 6S, 6aS, 10S, 10aR, 10bS)-5-(Acetyloxy)-3-ethenyldodecahydro-6, 10, 10b-trihydroxy-3, 4a, 7, 7, 10a-pentamethyl-1H-Naphtho[2, 1-b]pyran-1-one; (-)-Forskolin; Coleonol; Colforsin; ForsLean; HL 362; L 75-1362B; NSC 357088. Grades: Highly Purified. CAS No. 66575-29-9. Pack Sizes: 25mg. US Biological Life Sciences.
Forskolin is a naturally occurring diterpene from the Indian plant, Coleus forskohlii, that works as an activator of adenylate cyclase resulting in an increase in the intracellular concentration of cAMP. Group: Biochemicals. Grades: Highly Purified. CAS No. 66575-29-9. Pack Sizes: 50mg. US Biological Life Sciences.
Forskolin is a powerful activator of adenyklate cyclase, resulting in an increase of intracellular cAMP concentration.1,2 Activates adenylate cyclase leading to an increase in the intracellular concentration of cAMP. Widely used tool for the investigation of the role of cAMP as a second messenger with a broad range of potential therapeutic applications. Inotropic agent and vasodilator. Induces platelet aggregation. Inhibits ion channels by a mechanism that does not involve cAMP. Non-competitive inhibitor of nicotinic acetylcholine receptors. Group: Biochemicals. Grades: Highly Purified. CAS No. 66575-29-9. Pack Sizes: 10mg, 25mg, 100mg. US Biological Life Sciences.
Activates adenylate cyclase leading to an increase in the intracellular concentration of cAMP. Group: Biochemicals. Grades: Highly Purified. CAS No. 66575-29-9. Pack Sizes: 5mg. US Biological Life Sciences.
Potent, cell permeable adenylyl cyclase activator. Increases intracellular cAMP levels. Widely used tool to investigate cAMP as a second messenger. Inotropic and antihypertensive. Smooth muscle relaxant/vasodilator. Glucose transporter inhibitor. Platelet aggregation inhibitor. Stimulates lipolysis in fat cells. Non-competitive nicotinic acetylcholine receptors inhibitor. MAP kinase inhibitor. Upregulates mitochondrial uncoupling protein (UCP) mRNA levels in brown adipose tissue. Autophagy inhibitor. Hedgehog signaling inhibitor. Has antiglaucoma potential. Promotes neuronal differentiation of NSCs. Group: Biochemicals. Grades: Highly Purified. CAS No. 66575-29-9. Pack Sizes: 1mg, 5mg, 25mg, 50mg. US Biological Life Sciences.
Worldwide
Forskolin (Coleus forskohlii)
The major cell-permeable diterpene isolated from the Indian plant Coleus forskohlii. At low doses, it acts as a positive inotropic agent. At higher doses, it serves as a hypotensive and vasodilatory agent due to its actions as a smooth muscle relaxant. No major side effects are observed at effective doses. Forskolins pharmacological activities are due to its activation of adenylate cyclase (EC50 = 4uM), resulting in increased cAMP levels. The exact mechanism of forskolins positive inotropic effect is unknown but may be related to a cAMP-dependent increase in Na+ permeability that results in indirect augmentation of Ca2+ release. Inhibits MAP kinase in rat renal mesangial cells (IC50 = 25uM). Also acts as a Hh pathway antagonist. Shown to inhibit apoptosis in cerebellar granule cells and to induce apoptosis in resting human B lymphocytes. Group: Biochemicals. Grades: Highly Purified. CAS No. 66575-29-9. Pack Sizes: 5mg. US Biological Life Sciences.
The major cell-permeable diterpene isolated from the Indian plant Coleus forskohlii. At low doses, it acts as a positive inotropic agent. At higher doses, it serves as a hypotensive and vasodilatory agent due to its actions as a smooth muscle relaxant. No major side effects are observed at effective doses. Forskolins pharmacological activities are due to its activation of adenylate cyclase (EC50=4uM), resulting in increased cAMP levels. The exact mechanism of forskolins positive inotropic effect is unknown but may be related to a cAMP-dependent increase in Na+ permeability that results in indirect augmentation of Ca2+ release. Inhibits MAP kinase in rat renal mesangial cells (IC50= 25uM). Also acts as a Hh pathway antagonist. Shown to inhibit apoptosis in cerebellar granule cells and to induce apoptosis in resting human B lymphocytes. Group: Biochemicals. Grades: Highly Purified. CAS No. 66575-29-9. Pack Sizes: 10mg, 25mg. Molecular Formula: C??H??O?. US Biological Life Sciences.
Worldwide
Forskolin Hemisuccinate
Forskolin Hemisuccinate is a derivative fo Forskolin (F701800), a diterpene isolated from Coleus forskohlii, possessing vasodilating and cardiostimulatory properties. Forskolin Hemisuccinate was found to inhibit E-selectin gene transcription through a cAMP-dependent protein kinase pathway. Group: Biochemicals. Alternative Names: 1-[(3R, 4aR, 5S, 6S, 6aS, 10S, 10aR, 10bS)-3-Ethenyldodecahydro-6, 10, 10b-trihydroxy-3, 4a, 7, 7, 10a-pentamethyl-1-oxo-1H-naphtho[2, 1-b]pyran-5-yl] Ester Butanedioic Acid; 1H-Naphtho[2,1-b]pyran, Butanedioic Acid Deriv. Grades: Highly Purified. CAS No. 83797-56-2. Pack Sizes: 1mg. US Biological Life Sciences.
Forssman Antigen Pentaose is a paramount compound, serving as an invaluable instrument for the scrutiny and assessment of Forssman antigens. Tailored meticulously, it can used to study the diseases correlating with the existence of Forssman antigens, inclusive of the enigmatic Forssman syndrome. Synonyms: GalNAc-a-1,3-GalNAc-b-1,3-Gal-a-1,4-Gal-b1,4Glc. Molecular formula: C34H58N2O26. Mole weight: 910.82.
Forssman antigen triaose
Forssman antigen triaose is an invaluable compound in the realm of biomedical inquiry, standing as a pivotal catalyst in the advancement of diagnostic assays and vaccines, specifically tailored to study the intricate nature of Forssman antigen-induced ailments. Synonyms: GalNAc-a-1,3-GalNAc-b-1,3-Gal. Molecular formula: C22H38N2O16. Mole weight: 586.54.
Forsythia cyclohexanol ketone
Forsythia cyclohexanol ketone. Uses: For analytical and research use. Group: Impurity standards. CAS No. 189264-47-9. Molecular Formula: C8H10O3. Mole Weight: 154.17. Catalog: APB189264479.
Forsythia oleifera
Forsythia oleifera. Uses: For analytical and research use. Group: Impurity standards. CAS No. 487-39-8. Molecular Formula: C21H24O6. Mole Weight: 372.42. Catalog: APB487398.
Forsythin
Forsythin is purified from the fruits of Forsythia suspensa. Grades: >98%. CAS No. 96420-61-0.
Forsythoside A
Forsythoside A. Group: Biochemicals. Alternative Names: Forsythiaside. Grades: Plant Grade. CAS No. 79916-77-1. Pack Sizes: 20mg. Molecular Formula: C29H36O15, Molecular Weight: 624.586999999999. US Biological Life Sciences.
Worldwide
Forsythoside A
Cas No. 79916-77-1.
Forsythoside B
Forsythoside B. Group: Biochemicals. Grades: Plant Grade. CAS No. 81525-13-5. Pack Sizes: 20mg. Molecular Formula: C34H44O19, Molecular Weight: 756.7. US Biological Life Sciences.
Worldwide
Forsythoside E
Forsythoside E. Group: Biochemicals. Grades: Plant Grade. CAS No. 93675-88-8. Pack Sizes: 20mg. Molecular Formula: C20H30O12, Molecular Weight: 462.44. US Biological Life Sciences.
Worldwide
Forsythoside E
Forsythoside E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 93675-88-8. Molecular Formula: C20H30O12. Mole Weight: 462.45. Catalog: APB93675888.
Forsythoside G
Forsythoside G. Uses: For analytical and research use. Group: Impurity standards. CAS No. 129802-19-3. Molecular Formula: C35H46O19. Mole Weight: 770.73. Catalog: APB129802193.
Forsythoside I is a natural product isolated from forsythia suspense (thunb.) vahl, showing anti-inflammatory activities. Synonyms: Isoforsythoside A. Grades: 0.98. CAS No. 1177581-50-8. Molecular formula: C29H36O15. Mole weight: 624.59.
Fortimicin A
Produced by the strain of Micromonospora olivoasterospora, it has broad antibacterial spectrum and strong antibacterial activity, and is also effective to aminoglycoside antibiotic resistant bacteria producing 3'-phosphotransferase, 2''-nucleoside transferase, 6' and 2'-acetyltransferase. Synonyms: Astromicin; Astromicina; Astromicine; Astromicinum; Antibiotic KW-1070; 4-Amino-1-((aminoacetyl)methylamino)-1,4-dideoxy-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-beta-L-lyxo-heptopyranosyl)-6-O-methyl-L-chiro-inositol. Grades: 95%. CAS No. 55779-06-1. Molecular formula: C17H35N5O6. Mole weight: 405.49.
Fortimicin B
Produced by the strain of Micromonospora olivoasterospora, it has a weak antibacterial activity. Synonyms: Astromicin B; 4-Amino-1,4-dideoxy-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-beta-L-lyxo-heptopyranosyl)-6-O-methyl-1-(methylamino)-L-chiro-inositol. CAS No. 54783-95-8. Molecular formula: C15H32N4O5. Mole weight: 348.44.
Foward reaction buffer (10X) for P4410. Group: Molecular Biology. Alternative Names: For use with T4 polynucleotide kinase. Pack Sizes: 400ul, 2x1ml. US Biological Life Sciences.
Worldwide
Fosalvudine tidoxil
Fosalvudine tidoxil is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Fosalvudine tidoxil is a prodrug derived from Alovudine (HY-B1516). Fosalvudine tidoxil is less toxic than Alovudine and can be used for the research of HIV-1 infection. Group: Inhibitors. Alternative Names: FOSALVUDINE TIDOXIL. CAS No. 763903-67-9. Molecular formula: C35H64FN2O8PS. Mole weight: 722.935. Canonical SMILES: O=P (OC[C@H]1O[C@@H] (N (C (N2)=O)C=C (C)C2=O)C[C@@H]1F) (OCC (OCCCCCCCCCC)CSCCCCCCCCCCCC)O. Catalog: ACM763903679.
Fosamprenavir
Fosamprenavir (Amprenavir phosphate;GW 433908) is a phosphate ester proagent of the antiretroviral protease inhibitor Amprenavir, with improved solubility [1]. Anti- HIV infection [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Amprenavir phosphate; GW 433908. CAS No. 226700-79-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-78726.
Fosamprenavir
Fosamprenavir, also called as GW433908, Lexiva and Telzir, is an oral prodrug of the protease inhibitor (PI) amprenavir. Combined with other antiretroviral agents, Fosamprenavir is indicated for the treatment of patients with HIV infection, particularly those who have not previously received antiretroviral therapy. Synonyms: [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-1-phenyl-3-phosphonooxybutan-2-yl]carbamate; 3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-1-(phenylmethyl)-2-(phosphonooxy)propyl)carbamic acid C-(tetrahydro-3-furanyl) ester; fosamprenavir; 226700-81-8 (calcium) GW 433908; GW-433908; GW-908. Grades: > 95%. CAS No. 226700-79-4. Molecular formula: C25H36N3O9PS. Mole weight: 585.62.
Fosamprenavir calcium salt
Fosamprenavir calcium salt. Group: Biochemicals. Alternative Names: GW-433908G; Lexiva; Telzir. Grades: Highly Purified. CAS No. 226700-81-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C25H34CaN3O9PS. US Biological Life Sciences.
Worldwide
Fosamprenavir Calcium Salt
HIV protease inhibitor; water soluble prodrug of amprenavir. Synonyms: GW 433908G; Lexiva; GW433908G; GW-433908G. Grades: >98%. CAS No. 226700-81-8. Molecular formula: C25H34CaN3O9PS. Mole weight: 623.67.
Fosamprenavir Calcium Salt (GW-433908G, Lexiva, Telzir)
HIV protease inhibitor; water soluble prodrug of amprenavir. Group: Biochemicals. Alternative Names: GW-433908G; Lexiva; Telzir. Grades: Highly Purified. CAS No. 226700-81-8. Pack Sizes: 1mg. US Biological Life Sciences.
Fosamprenavir-d4 Calcium Salt (GW-433908G-d4, Lexiva-d4, Telzir-d4)
HIV protease inhibitor; water soluble prodrug of amprenavir. Group: Biochemicals. Alternative Names: GW-433908G-d4; Lexiva-d4; Telzir-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Fosaprepitant is a selective neurokinin-1 (NK-1) receptor antahonist. It is an antiemetic drug, which is a Aprepitant prodrug. Uses: Antiemetics. Synonyms: P-[3-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonic Acid; L 758298; [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)mor. Grades: > 95%. CAS No. 172673-20-0. Molecular formula: C23H22F7N4O6P. Mole weight: 614.42.
Fosaprepitant
Fosaprepitant. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid. CAS No. 172673-20-0. Molecular Formula: C23H22F7N4O6P. Mole Weight: 614.41. Catalog: APB172673200.
Fosaprepitant
Fosaprepitant (L-785298) is a proagent of Aprepitant (HY-10052). Fosaprepitant is a neurokinin-1 receptor antagonist, which is development for the prevention of chemotherapy-induced nausea and vomiting (CINV) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L-758298. CAS No. 172673-20-0. Pack Sizes: 1 mg. Product ID: HY-14407.
Fosaprepitant Benzyl Ester
Cas No. 889852-02-2.
Fosaprepitant Dibenzyl Ester
Fosaprepitant Dibenzyl Ester is a reactant in the synthesis of Fosaprepitant, which is a selective neurokinin-1 (NK-1) receptor antagonist used as an antiemetic drug. Synonyms: [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(Trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]-phosphonic Acid bis(Phenylmethyl) Ester; Dibenzyl Fosaprepitant; Fosaprepitant Impurity 16; Phosphonic acid, P-[3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]-, bis(phenylmethyl) ester; 2-Bis(phenylmethoxy)phosphoryl-5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-4H-1,2,4-triazol-3-one. Grades: >95%. CAS No. 265121-01-5. Molecular formula: C37H34F7N4O6P. Mole weight: 794.65.
Fosaprepitant dimeglumine
Fosaprepitant dimeglumine (MK-0517) is a proagent of Aprepitant (HY-10052). Fosaprepitant dimeglumine is a neurokinin-1 receptor antagonist, which is development for the prevention of chemotherapy-induced nausea and vomiting (CINV) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-0517; L785298. CAS No. 265121-04-8. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14407A.
Fosaprepitant Dimeglumine
Fosaprepitant is a selective neurokinin-1 (NK-1) receptor antahonist. Fosaprepitant is an antiemetic drug, a Aprepitant prodrug. Group: Biochemicals. Alternative Names: [3-[[ (2R, 3S) -2-[ (1R) -1-[3, 5-bis (trifluoromethyl) phenyl]ethoxy]-3- (4-fluorophenyl) -4-morpholinyl]methyl]-2, 5-dihydro-5-oxo-1H-1, 2, 4-triazol-1-yl]phosphonate 1-Deoxy-1-(methylamino)-D-glucitol; MK 0517. Grades: Highly Purified. CAS No. 265121-04-8. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Fosaprepitant Dimeglumine Impurity 1
Fosaprepitant Dimeglumine Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C37H57F6N6O16P. Mole Weight: 986.85. Catalog: APB08085.
Fosaprepitant Ester Impurity 11
Fosaprepitant Ester Impurity 11. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: dimethyl (3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-2,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate. Molecular Formula: C25H26F7N4O6P. Mole Weight: 642.46. Catalog: APB05964.
Fosaprepitant Impurity 1
A metabolite of Aprepitant. Synonyms: [2R-[2α(S*),3α]]-5-[[2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-Triazol-3-one. Grades: > 95%. CAS No. 170902-81-5. Molecular formula: C23H21F7N4O3. Mole weight: 534.44.
Fosaprepitant Impurity 10
Fosaprepitant Impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 502537-15-7. Molecular Formula: C21H19F6NO3. Mole Weight: 447.38. Catalog: APB502537157.
Fosaprepitant Impurity 11
Fosaprepitant Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1651828-04-4. Molecular Formula: C27H24F7NO3. Mole Weight: 543.48. Catalog: APB1651828044.
Fosaprepitant Impurity 12
Fosaprepitant Impurity 12. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C27H22F7NO2. Mole Weight: 525.47. Catalog: APB08089.