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| Product | Description | |
|---|---|---|
| Fozivudine tidoxil | Fozivudine tidoxil, an orally active thioether lipid-zidovudine (ZDV) conjugate with anti-HIV activity, is a reverse transcriptase inhibitor potentially for the treatment of HIV infection. Fozivudine tidoxil, a member of the NRTI family, is incorporated into the newly synthesized DNA strand during intracellular viral replication and irreversibly binds to the viral RT, thereby disrupting the reverse transcription of the virus. Synonyms: BM-211290; Fozivudine; 3'-Azido-3'-deoxy-5'-thymidylic Acid Mono(2-(decyloxy)-3-(dodecylthio)propyl) Ester; 3'-Azido-5'-O-{[2-(decyloxy)-3-(dodecylsulfanyl)propoxy](hydroxy)phosphoryl}-3'-deoxythymidine; 5'-Thymidylic acid, 3'-azido-3'-deoxy-, mono(2-(decyloxy)-3-(dodecylthio)propyl) ester. Grade: ≥95%. CAS No. 141790-23-0. Molecular formula: C35H64N5O8PS. Mole weight: 745.95. |  |
| FPA 124 | FPA 124 is an Akt/PKB inhibitor (IC50 = 100 nM) that inhibits cell proliferation in various cancer cell lines in vitro and decreases NF-κB activity and tumor load in vivo. Synonyms: FPA 124; FPA124; FPA-124; Akt Inhibitor XI; Dichloro[(2Z)-2-[(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazinecarbothioamide copper complex. CAS No. 902779-59-3. Molecular formula: C11H9Cl2CuN3O2S. Mole weight: 381.73. | |
| Fp-biotin | Fp-biotin. Synonyms: [10-[[5-[[5-[(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]pentyl]amino]-10-oxodecyl]phosphonofluoridic Acid Ethyl Ester; 10-Fluoroethoxyphosphinyl-N-biotinamidopentyldecanamide. CAS No. 259270-28-5. Molecular formula: C27H50FN4O5PS. Mole weight: 592.75. | |
| FP-biotin | FP-biotin. Group: Biochemicals. Alternative Names: [10- [ [5- [ [5- [ (3aS, 4S, 6aR) -Hexahydro-2-oxo-1H-thieno [3, 4-d] imidazol-4-yl] -1-oxopentyl] amino] pentyl] amino] -10-oxodecyl] phosphonofluoridic acid ethyl ester; 10-Fluoroethoxyphosphinyl -N-biotinamidopentyl decanamide . Grades: Highly Purified. CAS No. 259270-28-5. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C27H50FN4O5PS. US Biological Life Sciences. |  Worldwide |
| FP-Biotin. | FP-Biotin. Group: Biochemicals. Alternative Names: [10- [ [5- [ [5- [ (3aS, 4S, 6aR) -Hexahydro-2-oxo-1H-thieno [3, 4-d] imidazol-4-yl] -1-oxopentyl] amino] pentyl] amino] -10-oxodecyl] phosphonofluoridic Acid Ethyl Ester; 10-Fluoroethoxyphosphinyl -N-biotinamidopentyl decanamide . Grades: Highly Purified. CAS No. 259270-28-5. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| FP-Biotin-[d4] | FP-Biotin-[d4]. Synonyms: FP-Biotin D4. CAS No. 1219356-78-1. Molecular formula: C27H46D4FN4O5PS. Mole weight: 596.77. | |
| FPFT-2216 | FPFT-2216 is a "molecular glue" compound that degrades phosphodiesterase 6D (PDE6D), Ikaros (IKZF1) and Aiolos (IKZF3) zinc finger transcription factors, and casein kinase 1α (CK1α). Synonyms: 2,6-Piperidinedione, 3-[4-(4-methoxy-3-thienyl)-1H-1,2,3-triazol-1-yl]-. CAS No. 2367619-87-0. Molecular formula: C12H12N4O3S. Mole weight: 292.31. | |
| FPFT-2216 | FPFT-2216, a molecular glue compound, degrades phosphodiesterase 6D (PDE6D), zinc finger transcription factors Ikaros (IKZF1), Aiolos (IKZF3), and casein kinase 1? (CK1?). FPFT-2216 can be used for the research of cancer and inflammatory disease[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2367619-87-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145319. |  |
| Fpg Protein from Escherichia coli | ?90% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous glycerol solution, >20,000 units/mg protein. Group: Fluorescence/luminescence spectroscopy. |  |
| Fpg Protein from Escherichia coli, Recombinant | Fpg protein, a key enzyme in the DNA base excision repair pathway (BER), catalyses the excision of a broad spectrum of modified purines such as formamidopyrimidine (Fapy) and 8-oxoguanine (8-oxo-G). Fpg possess both DNA glycosylase activity that removes the mutated base and AP-lyase activity that releases ribose, leaving both 5'-and 3'-phosphorylated ends in the DNA. Several analytical methods based on Fpg protein activity in vitro were developed for detection and quantitation of oxidative damage to DNA mainly for FapyA, FapyG and 8-oxo-G. The fpg gene was cloned by Boiteux, et al. Fpg protein possess a zinc finger motif at its C-terminus (one zinc atom per molecule). ... Protein. Mole weight: mol wt 30.2 kDa (269 amino acids, predicted from the nucleotide sequence). Activity: >20 ,000 units/mg protein. Storage: -20°C. Form: buffered aqueous glycerol solution; Solution in 50% glycerol containing 50 mM potassium HEPES, pH 7.5, 1 mM DTT, 1 mM EDTA, and 200 mM NaCl. Source: E. coli. Species: Escherichia coli. Fapy-DNA glycosylase; deoxyribonucleate glycosidase; 2,6-diamino-4-hydroxy-5N-formamidopyrimidine-DNA glycosylase; 2,6-diamino-4-hydroxy-5 (N-methyl)formamidopyrimidine-DNA glycosylase; formamidopyrimidine-DNA glycosylase; DNA-formamidopyrimidine glycosidase; Fpg protein; DNA-formamidopyrimidine glycosylase; EC 3.2.2.23; 78783-53-6; |  |
| FPH1 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| FPH1 | FPH1 (BRD-6125) is a small molecule, which promotes expansion of iPS-derived hepatocytes. Synonyms: FPH 1; FPH-1; 2-(N-(5-Chloro-2-methylphenyl)methylsulfonamido)-N-(2,6-difluorophenyl)acetamide. Grade: >98%. CAS No. 708219-39-0. Molecular formula: C16H15ClF2N2O3S. Mole weight: 388.82. | |
| FPH2 | FPH2 is a small molecule, which promotes differentiation of iPS-derived hepatocytes. Synonyms: BRD-9424; BRD9424; BRD 9424; FPH2; FPH 2; FPH-2. Grade: >98%. CAS No. 957485-64-2. Molecular formula: C14H16ClN5O2S. Mole weight: 353.83. | |
| FPH2 | FPH2 induces of functional proliferation of primary human hepatocytes and may lead to the development of new therapeutics for liver diseases. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BRD-9424. CAS No. 957485-64-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12281. | |
| FPH2 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| FPI-1523 | FPI-1523 is a potent β-lactamase inhibitor with Kds of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. FPI-1523 also inhibits PBP2, with an IC50 of 3.2 μM. CAS No. 1452459-50-5. Molecular formula: C9H14N4O7S. Mole weight: 322.30. | |
| FPI-1523 sodium | FPI-1523 is a potent β-lactamase inhibitor with Kds of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. FPI-1523 also inhibits PBP2, with an IC50 of 3.2 μM. CAS No. 1452459-52-7. Molecular formula: C9H13N4NaO7S. Mole weight: 344.28. | |
| FPI-1602 | FPI-1602 is a β-lactamase inhibitor and shows marked antimicrobial activity against P. aeruginosa, E. coli, and Enterobacter spp. CAS No. 1452460-31-9. Molecular formula: C11H17N5O7S. Mole weight: 363.35. | |
| FPL 55712 | FPL 55712 is a leukotriene receptor antagonist that inhibits contraction of guinea pig trachealis induced by leukotrienes C4, D4, E4 and F4. Synonyms: FPL 55712; FPL55712; FPL-55712; 7-[3-(4-Acetyl-3-hydroxy-2-propylphenoxy)-2-hydroxypropoxy]-4-oxo-8-propyl-4H-1-benzopyran-2-carboxylic acid. Grade: ≥97% by HPLC. CAS No. 40785-97-5. Molecular formula: C27H30O9. Mole weight: 498.52. | |
| FPL 55712 | FPL 55712. Group: Biochemicals. Grades: Purified. CAS No. 40785-97-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| FPL-55712 | ?97% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| FPL 62064 | FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and cyclooxygenase (COX). FPL 62064 exhibits anti-inflammatory activity. Synonyms: 1H-Pyrazol-3-amine, N-(4-methoxyphenyl)-1-phenyl-; N-(4-methoxyphenyl)-1-phenyl-1H-Pyrazol-3-amine. Grade: 95%. CAS No. 103141-09-9. Molecular formula: C16H15N3O. Mole weight: 265.31. | |
| FPL64176 | FPL64176, a nondihydropyridine compound, is a potent agonist of L-type Ca 2+ channels with an EC 50 value of 16 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 120934-96-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103307. | |
| FPL 64176 | FPL 64176 is a potent L-type Ca2+ channel activator (EC50 = 16 nM) displaying 40-fold potency against Bay K 8644 as a positive inotrope in guinea pig atria. Uses: Calcium channel agonists. Synonyms: FPL-64176; FPL 64176; FPL64176; 2,5-Dimethyl-4-[2-(phenylmethyl)benzoyl]-1H-pyrrole-3-carboxylic acid methyl ester; Methyl 4-(2-benzylbenzoyl)-2,5-dimethyl-1H-pyrrole-3-carboxylate. Grade: ≥99% by HPLC. CAS No. 120934-96-5. Molecular formula: C22H21NO3. Mole weight: 347.41. | |
| FPL 64176 | FPL 64176. Group: Biochemicals. Grades: Purified. CAS No. 120934-96-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| FPL 64176 | ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| FPMINT | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| FPPQ | FPPQ is a dual-acting 5-HT3 (Ki = 0.9 nM) and 5-HT6 (Ki = 3 nM) receptor antagonist that exhibits antipsychotic and procognitive properties. CAS No. 1648745-46-3. Molecular formula: C21H19FN4O2S. Mole weight: 410.46. | |
| FPPS-IN-11 | FPPS-IN-11 is a novel allosteric non-bisphosphonate inhibitor of farnesyl pyrophosphate synthase (FPPS). Synonyms: 1-(Carboxymethyl)-1H-benzo[g]indole-2-carboxylic acid. Grade: >98%. CAS No. 1250273-31-4. Molecular formula: C15H11NO4. Mole weight: 269.25. | |
| FPQIrpic | FPQIrpic. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Iridium(III) bis(2-(2,4-difluorophenyl)quinoline)picolinate. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1621179-34-7. Molecular formula: C36H20F4IrN3O2. Mole weight: 795.11 g/mol. Product ID: ACM1621179347. Alfa Chemistry ISO 9001:2015 Certified. |  |
| FPR A14 | FPR A14 is a formyl peptide receptor (FPR) agonist that potently activates neutrophils in vitro (EC50 = 42 and 630 nM for neutrophil chemotaxis and Ca2+ mobilization, respectively). Synonyms: AG 14; AG14; AG-14; 1,3-Benzodioxolane-5-carboxylic acid 4'-benzyloxy-3'-methoxybenzylidene hydrazide. Grade: ≥99% by HPLC. CAS No. 329691-12-5. Molecular formula: C23H20N2O5. Mole weight: 404.42. | |
| FPR A14 | FPR A14. Group: Biochemicals. Grades: Purified. CAS No. 329691-12-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| FPR Agonist 43 | FPR Agonist 43 (compound 43) is a dual formyl peptide receptor 1 (FPR1) and formyl peptide receptor 2 (FPR2)/ALX agonist[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 903895-98-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19574. | |
| FPS-ZM1 | FPS-ZM1 is a high-affinity RAGE-specific blocker that inhibits amyloid-β binding to the V domain of RAGE with Ki of 25 ± 5 nM in RAGE-transfected CHO cells. It binds exclusively to RAGE and inhibits β-secretase activity and Aβ production. It also suppresses microglia activation and the neuroinflammatory response in brain. It penetrates the blood-brain barrier and binds to RAGE, thus reducing the protein levels of various cytokines. It inhibits RAGE-mediated influx of circulating Aβ40 and Aβ42 into the brain. It is not toxic to mice and can easily cross the blood-brain barrier in vivo. It might be a novel therapeutic agent to treat AD patients. Uses: Fps-zm1 might be a novel therapeutic agent to treat ad patients. Synonyms: FPS-ZM1; FPS ZM1; FPSZM1; FPS-ZM 1; FPS ZM-1; FPSZM 1; N-benzyl-4-chloro-N-cyclohexylbenzaMide; 4-Chloro-N-cyclohexyl-N-(phenylmethyl)benzamide. Grade: >98 %. CAS No. 945714-67-0. Molecular formula: C20H22ClNO. Mole weight: 327.85. | |
| FPS-ZM1 | FPS-ZM1 is a high-affinity RAGE inhibitor with a K i of 25 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 945714-67-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-19370. | |
| FPT | FPT, a 2-Aminotetralin, is an efficacious partial agonist at 5-HT 1A R , a full agonist at 5-HT 1B R and 5-HT 1D R with EC 50 s of 39.3 nM, 1.2 nM, 0.5 nM, respectively. FPT is a weak agonist at 5-HT 7 R. FPT shows in vivo efficacy as an antiepileptic in Fmr1 knockout mice and has anxiolytic-like and prosocial effects in Fmr1 knockout mice and other mouse models [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2048491-06-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-160887. | |
| FPTase, GST-Fusion, His Tag, Rat, Recombinant, E. coli | FPTase, GST-Fusion, His Tag, Rat, Recombinant, E. coli, is composed of an74 kDa ?- and 47 kDa ?-subunit. The ?-subunit is expressed as a GST-fusion construct with an N-terminal His Tag sequence. Group: Fluorescence/luminescence spectroscopy. | |
| FPTase, Rat, Recombinant, E. coli | A heterodimeric enzyme that catalyzes the transfer of a 15-carbon isoprenoid group to a variety of cellular proteins including Ras. Group: Fluorescence/luminescence spectroscopy. | |
| FPTQ | FPTQ is a potent mGluR1 antagonist and has anti-oxidant and anti-inflammatory effects in vitro and in vivo. Synonyms: 6-(1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl)quinoline. Grade: 99%. CAS No. 864863-72-9. Molecular formula: C17H12FN5. Mole weight: 305.31. | |
| FP-TZTP | FP-TZTP. Group: Biochemicals. Alternative Names: 3-[4-[(3-Fluoropropyl)thio]-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridine. Grades: Highly Purified. CAS No. 424829-90-3. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C11H16FN3S2. US Biological Life Sciences. | Worldwide |
| FQI1 | FQI1 is a Late SV40 Factor ( LSF ) inhibitor. FQI1 inhibits cell proliferation, with IC 50 s of 3, 0.79, 6.3 μM for NIH/3T3, HeLa, A549 cells. FQI1 can be used for cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 599151-35-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-124429. | |
| FQI1 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| FQI 1 | FQI 1 is a cell-permeable and reversible inhibitor of α-globin transcription factor CP2 (LSF; IC50 = 2.1 μM) and an antiproliferative. FQI 1 induces apoptosis in LSF-overexpressing cells, including Hepatocellular carcinoma (HCC cells). FQI 1 acts via inhibiting LSF-DNA binding. Uses: Antiproliferative. Synonyms: FQI 1; FQI1; FQI-1; 8-(2-ethoxyphenyl)-7,8-dihydro[1,3]dioxolo[4,5-g]quinolin-6(5H)-one; 8-(2-Ethoxy-phenyl)-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]quinolin-6-one. Grade: 99%. CAS No. 599151-35-6. Molecular formula: C18H17NO4. Mole weight: 311.33. | |
| FR054 | FR054 is an inhibitor of the Hexosamine Biosynthetic Pathway (HBP) enzyme PGM3, with a remarkable anti-breast cancer effect. FR054 induces in different breast cancer cells a dramatic decrease in cell proliferation and survival. In particular, in a model of Triple Negative Breast Cancer (TNBC) cells, MDA-MB-231, these effects are correlated to FR054-dependent reduction of both N- and O-glycosylation level that cause also a strong reduction of cancer cell adhesion and migration. Note: The correct structure for FR054 is CAS#35954-65-5 which is the 6S-isomer. Some vendors are selling wrong structure for FAR054 (the incorrect structure has CAS#10378-06-0, which is the 6R-isomer). Note this product is being supplied as ethanol solution at 100mg/mL. Uses: Designed for use in research and industrial production. Additional or Alternative Names: FR054; FR-054; FR 054. Product Category: Inhibitors. Appearance: Viscouse waxy semi-solid. CAS No. 35954-65-5. Molecular formula: C14H19NO8. Mole weight: 329.31. Purity: >98%. IUPACName: 5H-Pyrano[3,2-d]oxazole-6,7-diol, 5-[(acetyloxy)methyl]-3a,6,7,7a-tetrahydro-2-methyl-, diacetate (ester), (3aR,5R,6S,7R,7aR)-. Canonical SMILES: CC1=N[C@@]([C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](COC(C)=O)O2)([H])[C@@]2([H])O1. Product ID: ACM35954655-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| FR054 | FR054 is an inhibitor of the HBP enzyme PGM3, with a remarkable anti-breast cancer effect[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 35954-65-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-124909A. | |
| FR 110302 | This active molecular is a potent 5-lipoxygenase inhibitor which was originated by Fujisawa company for treating asthma. No-Development was reported for asthma in Japan. Synonyms: FR 110302; FR110302; FR-110302. 2,2-dibutyl-1,2,3,4-tetrahydro-5-(2-quinolinylmethoxy)-1-Naphthalenol. Grade: 98%. CAS No. 119256-94-9. Molecular formula: C28H35NO2. Mole weight: 417.58. | |
| FR 113680 | FR 113680 is a novel tripeptide substance P antagonist with NK1 receptor selectivity originated by Fujisawa for the treatment of Asthma. But no development are reported yet. Uses: Asthma. Synonyms: FR 113680; FR113680; FR-113680; Ac-Thr-trp(cho)-phe-N-mebzl. Ac-Thr-trp(cho)-phe-N-mebzl; N-acetyl-L-threonyl-1-formyl-D-tryptophyl-N-methyl-N-(phenylmethyl)-L-Phenylalaninamide. Grade: 98%. CAS No. 126088-92-4. Molecular formula: C35H39N5O6. Mole weight: 625.72. | |
| FR 121196 | FR 121196 is a potential antidementia drug originated by Fujisawa. Mechanism of Action is not undefined. FR 121196 can ameliorate the impaired memory of rat in the Morris water maze. No development was reported for Cognition disorders in Japan. Uses: Cognition disorders. Synonyms: FR 121196; FR 121196; FR 121196. N-(4-acetylpiperazin-1-yl)-4-fluorobenzenesulfonamide. Grade: 98%. CAS No. 133920-65-7. Molecular formula: C12H16FN3O3S. Mole weight: 301.34. | |
| FR122047 | FR122047 (hydrochloride) is a selective and oral active inhibitor of COX-1 with an IC 50 of 28 nM. FR122047 hydrochloride has antiplatelet, analgesic and anti-inflammatory effects in vivo [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 130717-51-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103386. | |
| FR 122047 hydrochloride | ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| FR 122047 hydrochloride | FR-122047 is a selective cyclooxygenase-1 (COX-1) inhibitor with IC50 values is 0.028μM for COX-1 and 65 μM for COX-2. FR-122047 displays 2300 fold greater selectivity towards inhibition of COX-1 over COX-2. It shows analgesic, anti-platelet and anti-inflammatory properties. No development was reported for the treatment of Pain, Rheumatoid arthritis and Thrombosis. Uses: Pain; rheumatoid arthritis; thrombosis. Synonyms: FR 122047 hydrochloride; 1-[[4,5-bis-(4-Methoxyphenyl)-2-thiazolyl]carbonyl]-4-methylpiperazine hydrochloride. Grade: >98 %. CAS No. 130717-51-0. Molecular formula: C23H25N3O3S.HCl. Mole weight: 459.99. | |
| FR 122047 hydrochloride | FR 122047 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 130717-51-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| FR122047 hydrochloride hydrate | FR122047 is a selective inhibitor of COX-1 with an IC50 value of 0.028 μM. Synonyms: 1-[[4,5-bis(4-methoxyphenyl)-2-thiazolyl]carbonyl]-4-methyl-piperazine, monohydrochloride, monohydrate. Grade: ≥98%. Molecular formula: C23H25N3O3S·HCl·H2O. Mole weight: 478. | |
| FR 139317 | FR 139317 is a selective Endothelin A receptor antagonist originated by Fujisawa. (Ki values are 1 nM and 7.3 μM at ETA and ETB subtypes respectively). No development was reported for the treatment of Cerebrovascular disorders, Coronary disorders, Diabetic nephropathies, Heart failure, Hypertension, Ischaemic heart disorders, Myocardial infarction and Renal failure. Uses: Cerebrovascular disorders; coronary disorders; diabetic nephropathies; heart failure; hypertension; ischaemic heart disorders; myocardial infarction; renal failure. Synonyms: FR 139317; FR139317; FR139317; PD 147953; PD147953; PD-147953; 2-((1-(Hexahydro-1H-azepinyl)carbonyl)amino-4-methylpentanoyl)-3-(-(1-methyl-1H-indolyl)propionyl)amino-3-(2-pyridyl)propionic acid. Grade: 98 %. CAS No. 142375-60-8. Molecular formula: C33H44N6O5. Mole weight: 604.75. | |
| FR 139317 | FR 139317. Group: Biochemicals. Grades: Purified. CAS No. 142375-60-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| FR-167356 | FR-167356, a benzofuran derivative, has been found to be an acuolar ATPase inhibitor and could probablye be useful in studies of some lytic bone diseases. Synonyms: FR-167356; FR167356; FR 167356; UNII-XF02B1HC8R. DSSTox_CID_28148; DSSTox_RID_82712; 2,6-dichloro-N-[3-(2-hydroxypropan-2-yl)-2-methyl-1-benzofuran-7-yl]benzamide. Grade: 98%. CAS No. 174185-16-1. Molecular formula: C19H17Cl2NO3. Mole weight: 378.25. | |
| FR-167653 | FR-167653 is a p38 mitogen-activated protein kinase inhibitor, which suppresses the development of endometriosis in a murine model. FR-167653 meliorates murine bleomycin-induced pulmonary fibrosis. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: FR-167653; FR 167653; FR167653. CAS No. 158876-66-5. Molecular formula: C24H20FN5O6S. Mole weight: 525.51. | |
| FR-167653 Free base | FR-167653, a pyrazolo?triazin derivative, has been found to be a cytokine inhibitor as well as P38 mitogen-activated protein kinase inhibitor and was once studied as an anticoagulant. Synonyms: FR167653; FR-167653; FR 167653; 1,?2-Ethanedione, 1-[7-(4-fluorophenyl)?-3,?4-dihydro-8-(4-pyridinyl)?pyrazolo[5,?1-c]?[1,?2,?4]?triazin-2(1H)?-yl]?-2-phenyl-. Grade: 98%. CAS No. 158876-65-4. Molecular formula: C24H18FN5O2. Mole weight: 427.43. | |
| FR-168888 | FR-168888, a guanidine compound, has been found to be a sodium hydrogen antiporter inhibitor that was once studied in myocardial ischaemia therapy. Synonyms: FR-168888; FR 168888; FR168888; Benzamide, N-(aminoiminomethyl)-3-(hydroxymethyl)-5-(1H-pyrrol-1-yl)-, methanesulfonate (1:1). Grade: 98%. CAS No. 168620-46-0. Molecular formula: C14H18N4O5S. Mole weight: 354.38. | |
| FR-168888 Free Base | The free base of FR-168888, a guanidine compound, has been found to be a sodium hydrogen antiporter inhibitor that was once studied in myocardial ischaemia therapy. Synonyms: FR-168888 free base; FR 168888 free base; FR168888 free base; SCHEMBL1388039; SCHEMBL8300855; Benzamide, N-(aminoiminomethyl)-3-(hydroxymethyl)-5-(1H-pyrrol-1-yl)-. Grade: 98%. CAS No. 168620-45-9. Molecular formula: C13H14N4O2. Mole weight: 258.28. | |
| FR 171113 | FR 171113 is a protease-activated receptor 1 (PAR1) antagonist displaying significant antiplatelet activity in vitro. It inhibits thrombin TRAP-6-induced platelet aggregation (IC50 = 2.5 μM) with no effect on coagulation time. Synonyms: FR 171113; FR171113; FR-171113; 2-[3-(4-Chlorophenyl)-2-[(2,4-dichlorobenzoyl)imino]-4-oxo-5-thiazolidinylidene]-acetic acid methyl ester. Grade: ≥98% by HPLC. CAS No. 173904-50-2. Molecular formula: C19H11Cl3N2O4S. Mole weight: 469.73. | |
| FR 171113 | FR 171113. Group: Biochemicals. Grades: Purified. CAS No. 173904-50-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| FR-171113 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| FR 179642 | FR 179642 is an impurity of Micafungin, which is an antifungal agent. Synonyms: FR-179642; FR179642; Pneumocandin M1; 1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0; 1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]-4-[(S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0; CMICA; FR 133303. Grade: ≥95%. CAS No. 168110-44-9. Molecular formula: C35H52N8O20S. Mole weight: 936.89. | |
| FR-179642 | FR-179642. Group: Biochemicals. Grades: Highly Purified. CAS No. 168110-44-9. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C35H52N8O20S. US Biological Life Sciences. | Worldwide |
| FR-179642 | FR-179642 is a cyclic peptide and an important intermediate in producing micafungin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: FR-133303; FR 133303; FR133303; FR-179642; FR 179642; FR179642; Micafungin FR-179642 impurity; Pneumocandin M1. Product Category: Others. Appearance: Solid powder. CAS No. 168110-44-9. Molecular formula: C35H52N8O20S. Mole weight: 936.9. Purity: >98%. IUPACName: 5-((1S,2S)-2-((2R,6S,9S,11R,12R,14aS,15S,16S,20S,23S,25aS)-9-amino-20-((R)-3-amino-1-hydroxy-3-oxopropyl)-2,11,12,15-tetrahydroxy-6-((R)-1-hydroxyethyl)-16-methyl-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-23-yl)-1,2-dihydroxyethyl)-2-hydroxyphenyl hydrogen sulfate. Canonical SMILES: C[C@@H](O)[C@@H]1NC(=O)[C@@H](N)C[C@@H](O)[C@@H](O)NC(=O)[C@@H]2[C@@H](O)[C@@H](C)CN2C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]3C[C@@H](O)CN3C1=O)[C@H](O)[C@@H](O)c4ccc(O)c(OS(=O)(=O)O)c4)[C@H](O)CC(=O)N. Product ID: ACM168110449. Alfa Chemistry ISO 9001:2015 Certified. | |
| FR180204 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| FR 180204 | FR 180204. Group: Biochemicals. Grades: Purified. CAS No. 865362-74-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| FR 180204 | FR 180204 is an ATP-competitive and selective ERK inhibitor. FR 180204 inhibits ERK1 and ERK2 with IC 50 s of 0.51 μM ( K i =0.31 μM) and 0.33 μM ( K i =0.14 μM), respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 865362-74-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12275. | |
| FR 180204 | FR180204 is a novel and selective inhibitor of extracellular signal-regulated kinase (ERK), which may be a potential new therapy for rheumatoid arthritis.FR180204 showed activity to inhibit ERKs (IC50 values are 0.14 and 0.31 μM for ERK2 and ERK1 respectively). Synonyms: 865362-74-9; FR 180204; FR-180204; ERK inhibitor II; 5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE; 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-2H-pyrazolo[3,4-c]pyridazin-3-amine; 4C7X7GV82C; CHEMBL259551; 1H-Pyrazolo(3,4-C)pyridazin-3-amine, 5-(2-phenylpyrazolo(1,5-a)pyridin-3-yl)-; 5-(2-Phenylpyrazolo(1,5-a)pyridin-3-yl)-2H-pyrazolo(3,4-C)pyridazin-3-amine; 5-{2-phenyl. Grade: 0.98. CAS No. 865362-74-9. Molecular formula: C9H11N5O4. Mole weight: 253.22. | |
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