A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Fosinopril (SQ28555 free acid) is the ester proagent of angiotensin-converting enzyme (ACE) inhibitor with an IC50 value of 0.18 μM. Fosinopril demonstrates a non-competitive inhibition effect on ACE activity with an Ki value of 1.675 μM. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Fosinopril. Product Category: Inhibitors. Appearance: Crystalline solid. CAS No. 98048-97-6. Molecular formula: C30H46NO7P. Mole weight: 563.66. Canonical SMILES: O=C(O)[C@H]1N(C(C[P@@](CCCCC2=CC=CC=C2)(O[C@H](OC(CC)=O)C(C)C)=O)=O)C[C@H](C3CCCCC3)C1. Density: 1.173 g/cm³. Product ID: ACM98048976. Alfa Chemistry ISO 9001:2015 Certified.
Fosinoprilat
Fosinoprilat is a metabolite of Fosinopril. Fosfenopril is a potent angiotensin converting enzyme (ACE) inhibitor. Synonyms: Fosinopril sodium EP Impurity A; Fosinopril Related Compound A; Fosinopril diacid; Fosfenopril; Fosinoprilic acid. Grade: > 95%. CAS No. 95399-71-6. Molecular formula: C23H34NO5P. Mole weight: 435.50.
Fosinoprilat acyl-b-D-glucuronide
Fosinoprilat acyl-b-D-glucuronide, an esteemed biomedical compound, stands as a valuable solution for individuals grappling with hypertension and heart failure. This pharmacological entity acts as an active metabolite of Fosinopril, showcasing its prowess as an angiotensin-converting enzyme inhibitor. By judiciously impeding the angiotensin-converting enzyme's activity and dwindling the generation of angiotensin II, Fosinoprilat acyl-b-D-glucuronide splendidly fosters vasodilation and effectively curtails blood pressure. Synonyms: trans-4-Cyclohexyl-1-[[hydroxy(4-phenylbutyl)phosphinyl]acetyl]-L-proline b-D-glucopyranuronosyl ester; L-Proline, 4-cyclohexyl-1-[2-[hydroxy(4-phenylbutyl)phosphinyl]acetyl]-, β-D-glucopyranuronosyl ester, (4S)-; (4S)-4-Cyclohexyl-1-[2-[hydroxy(4-phenylbutyl)phosphinyl]acetyl]-L-proline β-D-glucopyranuronosyl ester; L-Proline, 4-cyclohexyl-1-[[hydroxy(4-phenylbutyl)phosphinyl]acetyl]-, β-D-glucopyranuronosyl ester, (4S)-; L-Proline, 4-cyclohexyl-1-[[hydroxy(4-phenylbutyl)phosphinyl]acetyl]-, β-D-glucopyranuronosyl ester, trans-. CAS No. 113411-09-9. Molecular formula: C29H42NO11P. Mole weight: 611.62.
Fosinoprilat-[d7]
Fosinoprilat-[d7] is the labelled analogue of Fosinoprilat, which is a metabolite of Fosinopril. Fosinopril is an angiotensin converting enzyme inhibitor used for the treatment of hypertension and some types of chronic heart failure. Synonyms: Fosinoprilat D7; (4S)-4-Cyclohexyl-1-[[hydroxy(4-phenylbutyl-d7)phosphinyl]acetyl]-L-proline; trans-4-Cyclohexyl-1-[[hydroxy(4-phenylbutyl-d7)phosphinyl]acetyl]-L-proline; Fosfenopril-d7; Fosinoprilic-d7 Acid; SQ 27519-d7; Fosinopril EP Impurity A-d7. Grade: >95%. CAS No. 1279220-43-7. Molecular formula: C23H27D7NO5P. Mole weight: 442.55.
Fosinoprilat disodium salt
Fosinoprilat disodium salt. Group: Biochemicals. Alternative Names: (4S) -4-Cyclohexyl-1-[2-[hydroxy (4-phenylbutyl) phosphinyl]acetyl]-L-proline disodium salt; Fosfenopril disodium salt; Fosinoprilic acid disodium salt. Grades: Highly Purified. CAS No. 95399-71-6. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C23H32NNa2O5P. US Biological Life Sciences.
Worldwide
Fosinopril-d7 sodium salt
One of the isotopic labelled salt form of Fosinopril, which has been found to be an angiotensin converting enzyme (ACE) inhibitor and could be used as antihypertensive agent. Synonyms: (4S)-4-Cyclohexyl-1-[[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-L-proline Sodium Salt-d7. Molecular formula: C30H38D7NO7P.Na. Mole weight: 592.70.
A labeled phosphinic acid containing angiotensin converting enzyme (ACE) inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Fosinopril Related Compound A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Fosinopril Related Compound B
Fosinopril Related Compound B is an impurity of Fosinopril. Fosfenopril is a potent angiotensin converting enzyme (ACE) inhibitor. Synonyms: (4S)-4-Cyclohexyl-1-[(R)-[(S)-1-hydroxy-2-methylpropoxy](4-phenylbutyl)phosphinyl]acetyl-D-proline propionate (ester), hemibarium salt, sesquihydrate. Grade: > 95%. Molecular formula: C30H45NO7P.1/2Ba.3/2H2O. Mole weight: 658.34.
Fosinopril Related Compound C
Fosinopril Related Compound C is an impurity of Fosinopril. Fosfenopril is a potent angiotensin converting enzyme (ACE) inhibitor. Synonyms: (4S)-4-Cyclohexyl-1-[(RS)-[(RS)-1-hydroxy-2-methylpropoxy](4-phenylbutyl)phosphinyl]acetyl-L-proline propionate (ester), sodium salt. Molecular formula: C30H45NNaO7P. Mole weight: 585.65.
Fosinopril Related Compound C
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Fosinopril Related Compound D
Fosinopril Related Compound D is an impurity of Fosinopril. Fosfenopril is a potent angiotensin converting enzyme (ACE) inhibitor. Synonyms: (4R)-4-Cyclohexyl-1-[(R)-[(S)-1-hydroxy-2-methylpropoxy](4-phenylbutyl)phosphinyl]acetyl-L-proline propionate (ester), sodium salt. Molecular formula: C30H45NNaO7P. Mole weight: 585.65.
Fosinopril Related Compound D
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Fosinopril Related Compound E
Fosinopril Related Compound E is an impurity of Fosinopril. Fosfenopril is a potent angiotensin converting enzyme (ACE) inhibitor. Synonyms: (4S)-4-Phenyl-1-[(R)-[(S)-1-hydroxy-2-methylpropoxy](4-phenylbutyl)phosphinyl]acetyl-L-proline propionate (ester), sodium salt. Molecular formula: C30H39NNaO7P. Mole weight: 579.61.
Fosinopril Related Compound E
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Fosinopril Related Compound F
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Fosinopril Related Compound F
Fosinopril Related Compound F is an impurity of Fosinopril. Fosfenopril is a potent angiotensin converting enzyme (ACE) inhibitor. Synonyms: (4S)-4-Cyclohexyl-1-[(R)-[(S)-1-hydroxypropoxy](4-phenylbutyl)phosphinyl]acetyl-L-proline propionate (ester), sodium salt. Molecular formula: C29H43NNaO7P. Mole weight: 571.62.
Fosinopril Related Compound G
Fosinopril Related Compound G is an impurity of Fosinopril. Fosfenopril is a potent angiotensin converting enzyme (ACE) inhibitor. Synonyms: (4-Phenylbutyl)phosphinylacetic acid, disodium salt. Molecular formula: C12H15Na2O4P. Mole weight: 300.20.
Fosinopril Related Compound G
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Fosinopril Related Compound H
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Fosinopril sodium
Fosinopril Sodium is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension and some types of chronic heart failure. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SQ28555. CAS No. 88889-14-9. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0382.
Fosinopril sodium EP Impurity B
Fosinopril sodium EP Impurity B is an impurity of Fosinopril. Fosfenopril is a potent angiotensin converting enzyme (ACE) inhibitor. Synonyms: (2RS,4RS)-4-cyclohexyl-1-[[(RS)-[(1SR)-2-methyl-1-(propanoyloxy)propoxy](4-phenylbutyl)phosphoryl]acetyl]-pyrrolidine-2-carboxylic acid. Molecular formula: C30H46NO7P. Mole weight: 563.67.
Fosinopril sodium EP Impurity C
Fosinopril sodium EP Impurity C is an impurity of Fosinopril. Fosfenopril is a potent angiotensin converting enzyme (ACE) inhibitor. Synonyms: mixture of (2S,4S)-4-cyclohexyl-1-[[(R)-[(1R)-2-methyl-1-(propanoyloxy)propoxy](4-phenylbutyl)phosphoryl]acetyl]pyrrolidine-2-carboxylic acid and (2S,4S)-4-cyclohexyl-1-[[(S)-[(1S)-2-methyl-1-(propanoyloxy)propoxy](4-phenylbutyl)phosphoryl]acetyl]pyrrolidine-2-carboxylic acid. Molecular formula: C30H46NO7P. Mole weight: 563.67.
Fosinopril sodium EP Impurity D
Fosinopril sodium EP Impurity D is an impurity of Fosinopril. Fosfenopril is a potent angiotensin converting enzyme (ACE) inhibitor. Synonyms: (2S,4R)-4-cyclohexyl-1-[[(R)-[(1S)-2-methyl-1-(propanoyloxy)propoxy](4-phenylbutyl)phosphoryl]acetyl]-pyrrolidine-2-carboxylic acid. CAS No. 1356446-78-0. Molecular formula: C30H46NO7P. Mole weight: 563.67.
Fosinopril sodium EP Impurity E
Fosinopril sodium EP Impurity E is an impurity of Fosinopril. Fosfenopril is a potent angiotensin converting enzyme (ACE) inhibitor. Synonyms: Phenyl Fosinopril; (2S,4S)-1-[[(R)-[(1S)-2-methyl-1-(propanoyloxy)propoxy]-(4-phenylbutyl)phosphoryl]acetyl]-4-phenylpyrrolidine-2-carboxylic acid. Grade: > 95%. Molecular formula: C30H40NO7P. Mole weight: 557.63.
Fosinopril sodium EP Impurity F
Fosinopril sodium EP Impurity F is an impurity of Fosinopril. Fosfenopril is a potent angiotensin converting enzyme (ACE) inhibitor. Synonyms: (2S,4S)-4-cyclohexyl-1-[[(R)-(4-phenylbutyl)[(1S)-1-(propanoyloxy)propoxy]phosphoryl]acetyl]pyrrolidine-2-carboxylic acid. Grade: > 95%. Molecular formula: C29H44NO7P. Mole weight: 549.65.
Fosinopril sodium EP Impurity H
Fosinopril sodium EP Impurity H is an impurity of Fosinopril. Fosfenopril is a potent angiotensin converting enzyme (ACE) inhibitor. Molecular formula: C30H46NO7P. Mole weight: 563.67.
Fosinopril sodium EP Impurity I
Fosinopril sodium EP Impurity I is an impurity of Fosinopril. Fosfenopril is a potent angiotensin converting enzyme (ACE) inhibitor. Synonyms: [(RS)-[(1SR)-2-methyl-1-(propanoyloxy)propoxy]-(4-phenylbutyl)phosphoryl]acetic acid; Fosinopril sodium Impurity 2. Molecular formula: C19H29O6P. Mole weight: 384.41.
Fosinopril sodium EP Impurity K
Fosinopril sodium EP Impurity K is an impurity of Fosinopril. Fosfenopril is a potent angiotensin converting enzyme (ACE) inhibitor. Synonyms: Fosinopril sodium Impurity 1. Molecular formula: C16H27NO3. Mole weight: 281.39.
Fosinopril sodium EP Impurity N
Fosinopril sodium EP Impurity N is an impurity of Fosinopril. Fosfenopril is a potent angiotensin converting enzyme (ACE) inhibitor. Synonyms: (2S,4S)-4-cyclohexyl-1-[(2S,4S)-4-cyclohexyl-1-[[(R)-[(1S)-2-methyl-1-(propanoyloxy)propoxy](4-phenylbutyl)phosphoryl]acetyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carboxylic acid. Molecular formula: C41H63N2O8P. Mole weight: 742.93.
Fosinopril sodium Impurity 3
Fosinopril sodium Impurity 3 is an impurity of Fosinopril. Fosfenopril is a potent angiotensin converting enzyme (ACE) inhibitor. Synonyms: trans-4-Cyclohexyl-1-(1,3-dioxopentyl)-L-proline. CAS No. 149760-14-5. Molecular formula: C16H25NO4. Mole weight: 295.37.
Fosinopril sodium salt
Fosinopril Sodium is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor. Synonyms: Monopril; Staril; Dynacil; Fosinil; Tenso Stop; Tensocardil; Sodium, Fosinopril; SQ 28,555; SQ 28555; SQ-28,555; SQ-28555; SQ28,555; SQ28555. Grade: >98%. CAS No. 88889-14-9. Molecular formula: C30H45NO7P·Na. Mole weight: 585.64.
A phosphinic acid containing angiotensin converting enzyme (ACE) inhibitor. Group: Biochemicals. Alternative Names: Dynacil, Elidiur, Fosinorm, Monopril, Staril, Tensozide, (4S) -4-Cyclohexyl-1-[[ (R) -[ (1S) -2-methyl-1- (1-oxopropoxy) propoxy] (4-phenylbutyl) phosphinyl]acetyl]-L-proline. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
FOSL1 degrader 1
FOSL1 degrader 1 (4) is a T-5224-PROTAC, potently degrade FOSL1 (AP-1) to suppress cancer stemness gene expression in HNSCC. FOSL1 degrader 1 (4) effectively eliminate HNSCC cancer stem cells to inhibit tumor growth through degrading FOSL1. FOSL1 degrader 1 (4) displays around 30- to 100-fold increased potency over T-5224 (Pink: T-5224 (HY-12270); Black: Linker (HY-130200); Blue: Pomalidomide (HY-10984))[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-162723.
Foslevcromakalim
Foslevcromakalim (QLS-101) is a ATP-sensitive potassium channel opener. Foslevcromakalim is the proagent used for ocular hypotensive effect [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: QLS-101. CAS No. 1802655-72-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-152847.
Foslinanib disodium
Foslinanib disodium is an anticancer compound that inhibits the formation of vasculogenic mimicking networks in C8161 and SK-MEL-28 melanoma cells at concentrations ranging from less than or equal to 5 to 10 nM. Synonyms: TRX818 Sodium; Foslinanib Sodium; CVM-1118 disodium; TRX-818 disodium; Sodium 2-(3-fluorophenyl)-6-methoxy-4-oxo-1,4-dihydroquinolin-5-yl phosphate; 4(1H)-Quinolinone, 2-(3-fluorophenyl)-6-methoxy-5-(phosphonooxy)-, sodium salt (1:2); Sodium 2-(3-fluorophenyl)-4-hydroxy-6-methoxyquinolin-5-yl phosphate. Grade: ≥95%. CAS No. 1256037-62-3. Molecular formula: C16H11FNNa2O6P. Mole weight: 409.21.
Fosmanogepix
Fosmanogepix (APX001) is a broad-spectrum agent against invasive fungal infections. Fosmanogepix (APX001) targets the conserved Gwt1 enzyme required for the localization of glycosylphosphatidylinositol-anchored mannoproteins in fungi. This inhibition prevents the appropriate localization of cell wall mannoproteins, which compromises cell wall integrity, biofilm formation, germ tube formation, and fungal growth. Fosmanogepix (APX001) can be used for invasive fungal infections research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: APX001; E1211. CAS No. 2091769-17-2. Pack Sizes: 5 mg. Product ID: HY-119726.
Fosmidomycin
Fosmidomycin is produced by the strain of Streptomyces lavendulae 8006. Fosmidomycin has anti-gram-positive and anti-gram-negative activities. Synonyms: Fosmidomycina; 3-(N-hydroxyformamido)propylphosphonic acid; FR-31564. Grade: 95%. CAS No. 66508-53-0. Molecular formula: C4H10NO5P. Mole weight: 183.10.
Fosmidomycin sodium salt
Fosmidomycin is an antimalarial and antibiotic originally isolated from culture broths of bacteria of the genus Streptomyces and has been used as an inhibitor of DOXP reductoisomerase, a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis. Synonyms: Antibiotic FR31564; FR31564; P-[3-(formylhydroxyamino)propyl]-phosphonic acid, monosodium salt; (3-(N-Hydroxyformamido)propyl)phosphonic acid sodium salt; Phosphonic acid, (3-(formylhydroxyamino)propyl)-, monosodium salt. Grade: ≥95%. CAS No. 66508-37-0. Molecular formula: C4H9NO5P.Na. Mole weight: 205.08.
Fosmidomycin sodium salt
Fosmidomycin sodium salt is a phosphonic acid antibiotic and a antimalarial agent, which is active against both Gram-negative and Gram-positive bacteria. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FR-31564. CAS No. 66508-37-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-112853.
Fosmidomycin sodium salt
Fosmidomycin sodium salt. Group: Biochemicals. Alternative Names: 3-(N-Formyl-N-hydroxyamino)propyl phosphonic acid sodium salt; FR31564. Grades: Highly Purified. CAS No. 66508-37-0. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C4H9NNaO5P. US Biological Life Sciences.
Worldwide
Fosmidomycin, Sodium Salt (3-(N-Formyl-N-hydroxyamino)propyl Phosphonic Acid, Sodium Salt, FR31564)
An antibiotic. Group: Biochemicals. Alternative Names: 3-(N-Formyl-N-hydroxyamino)propyl Phosphonic Acid, Sodium Salt, FR31564. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Fosnetupitant (Pronetupitant) a methylene phosphate proagent of Netupitant. Fosnetupitant (Pronetupitant) exhibits a pK i of 9.5 for human NK 1 receptor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Pronetupitant. CAS No. 1703748-89-3. Pack Sizes: 5 mg. Product ID: HY-17615.
Fosnetupitant
Fosnetupitant, a piperazine derivative, has been found to be a NK1 receptor antagonist that could be used in nausea and vomiting caused by chemotherapy. It was just reported a Phase II trail in Japan. Synonyms: Fosnetupitant; T672P80L2S; Fosnetupitant; Piperazinium, 4-(5-((2-(3,5-bis(trifluoromethyl)phenyl)-2-methyl-1-oxopropyl)methylamino)-4-(2-methylphenyl)-2-pyridinyl)-1-methyl-1-((phosphonooxy)methyl)-, inner salt. Grade: 98%. CAS No. 1703748-89-3. Molecular formula: C31H35F6N4O5P. Mole weight: 688.61.
Fosquidone is a water-soluble pentacyclic pyrolloquinone analogue of mitoquidone with potential antineoplastic activity. Currently, the mechansim of action of fosquidone is unknown. In vitro studies indicate that this agent does not bind to DNA or inhibit topoisomerases. Synonyms: GR 63178K; GR63178A; GR-63178A; NSC 611615; benzyl (14-methyl-8,13-dioxo-5,8,13,14-tetrahydrobenzo[5,6]isoindolo[2,1-b]isoquinolin-9-yl) hydrogen phosphate. CAS No. 114517-02-1. Molecular formula: C28H22NO6P. Mole weight: 499.46.
Fosravuconazole
Fosravuconazole is an azole antifungal agent potentially for the treatment of fungal infections, as a water-soluble prodrug of ravuconazole that is being developed by the Drugs for Neglected Diseases Initiative (DNDi). Uses: A water-soluble prodrug of ravuconazole that is being developed by the drugs for neglected diseases initiative (dndi). Synonyms: Fosravuconazole; BEF-1224; BMS-379224; E-1224; BEF1224; BMS379224; E1224.[(2R,3R)-3-[4-(4-cyanophenyl)-1,3-thiazol-2-yl]-2-(2,4-difluorophenyl)-1-(1,2,4-triazol-1-yl)butan-2-yl]oxymethyl dihydrogen phosphate. Grade: ≥98%. CAS No. 351227-64-0. Molecular formula: C23H20F2N5O5PS. Mole weight: 547.09.
Fosravuconazole
Fosravuconazole (BMS-379224), a proagent of Ravuconazole, is an orally active broad spectrum antifungal agent. Fosravuconazole can be used for candidiasis, onychomycosis and parasitemia research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-379224; E-1224. CAS No. 351227-64-0. Pack Sizes: 1 mg. Product ID: HY-16779.
Fos-related antigen 1 human
recombinant, expressed in insect cells, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
Fosribnicotinamide-d4
Fosribnicotinamide-d4 (?-Nicotinamide mononucleotide-d4) is the deuterium labeled Fosribnicotinamide. Fosribnicotinamide is a product of the nicotinamide phosphoribosyltransferase (NAMPT) reaction and a key NAD+ intermediate. The pharmacological activities of Fosribnicotinamide include its role in cellular biochemical functions, cardioprotection, diabetes, Alzheimer's disease, and complications associated with obesity[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: ?-Nicotinamide mononucleotide-d4; ?-NM-d4; NMN-d4. Pack Sizes: 1 mg. Product ID: HY-F0004S.
Fostamatinib
Fostamatinib (R788) is the oral proagent of the active compound R406 [1]. R406 is an orally available and competitive Syk/FLT3 inhibitor with a K i of 30 nM and an IC 50 of 41 nM [2]. R406 also inhibits Lyn (IC 50 =63 nM) and Lck (IC 50 =37 nM) [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R788. CAS No. 901119-35-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13038A.
Fostamatinib
Fostamatinib, a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM, strongly inhibiting Syk but not Lyn, and 5-fold less potent to Flt3. Synonyms: R788; R 788; R-788. Grade: >98%. CAS No. 901119-35-5. Molecular formula: C23H26FN6O9P. Mole weight: 580.46.
Fostamatinib Disodium
Fostamatinib Disodium (R788 Disodium) is the oral proagent of the active compound R406 [1]. R406 is an orally available and competitive Syk/FLT3 inhibitor with a K i of 30 nM and an IC 50 of 41 nM [2]. R406 also inhibits Lyn (IC 50 =63 nM) and Lck (IC 50 =37 nM) [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R788(Disodium). CAS No. 1025687-58-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13038.
Fostamatinib disodium hexahydrate
Fostamatinib disodium hexahydrate. Group: Biochemicals. Alternative Names: 6-[[5-Fluoro-2-[ (3, 4, 5-trimethoxyphenyl) amino]-4-pyrimidinyl]amino]-2, 2-dimethyl-4-[ (phosphonooxy) methyl]-2H-pyrido[3, 2-b]-1, 4-oxazin-3 (4H) -one sodium salt hydrate. Grades: Highly Purified. CAS No. 914295-16-2. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C23H36FN6Na2O15P. US Biological Life Sciences.
Worldwide
Fostamatinib sodium
R788 (Fostamatinib) disodium, a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. Phase 3. Synonyms: R935788. Code names: R788 sodium. R935788 sodium. CAS No. 1025687-58-4. Molecular formula: C23H24FN6O9P.2Na. Mole weight: 624.42.
Fosteabine
Fosteabine is an oral and prodrug cytarabine analogue. It is resistant to deoxycytidine deaminase. Synonyms: Cytarabine ocfosfate; Stearyl-ara-cmp; YNK 01; YNK-01; YNK01. CAS No. 73532-83-9. Molecular formula: C27H50N3O8P. Mole weight: 575.68.
Fostemsavir
Fostemsavir (BMS-663068) is the phosphonooxymethyl prodrug of BMS-626529. Fostemsavir (BMS-663068) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4 + T cells. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-663068. CAS No. 864953-29-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-15440A.
Fostemsavir Tris
Fostemsavir Tris (BMS-663068 (Tris)) is the phosphonooxymethyl proagent of BMS-626529. Fostemsavir Tris (BMS-663068 (Tris)) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4 + T cells. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-663068 Tris. CAS No. 864953-39-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15440B.
Fosthiazate
Fosthiazate is a broad-spectrum nematicide against various plant parasitic nematodes, including Meloidogyne spp. , Globodera spp. , and Pratylenchus spp. , through inhibiting the synthesis of acetylcholinesterase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 98886-44-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W020785.
Fostriecin
The most fully characterised member of a family of phosphate esters of a triene antibiotic; a topoisomerase II inhibitor; selective inhibition of protein phosphatase PP2A. Synonyms: (1E,7E,9E,11E)-3,6,13-trihydroxy-3-methyl-1-(6-oxo-3,6-dihydro-2H-pyran-2-yl)trideca-1,7,9,11-tetraen-4-yl dihydrogen phosphate; 2H-Pyran-2-one, 5,6-dihydro-6-[3,6,13-trihydroxy-3-methyl- 4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-, monosodiumsalt. Grade: >95% by HPLC. CAS No. 87810-56-8. Molecular formula: C19H27O9P. Mole weight: 430.39.
Fostriecin sodium salt
Fostriecin sodium salt is a protein phosphatase types 2A (PP2A) and 4 (PP4) inhibitor (IC50 = 1.5 nM and 3 nM, respectively). It also has an inhibitory effect on topoisomerase II (IC50 = 40 μM) and protein phosphatase type 1 (PP1) (IC50 = 131 μM). Fostriecin is found in Streptomyces pulveraceous. Uses: Enzyme inhibitors. Synonyms: Fostriecin Sodium; Antibiotic CI 920 sodium salt; (6R)-5,6-Dihydro-6-[(1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-2H-pyran-2-one sodium salt. Grade: ≥98% by HPLC. CAS No. 87860-39-7. Molecular formula: C19H26O9PNa. Mole weight: 452.37.