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| Product | Description | |
|---|---|---|
| FR 113680 | FR 113680 is a novel tripeptide substance P antagonist with NK1 receptor selectivity originated by Fujisawa for the treatment of Asthma. But no development are reported yet. Uses: Asthma. Synonyms: FR 113680; FR113680; FR-113680; Ac-Thr-trp(cho)-phe-N-mebzl. Ac-Thr-trp(cho)-phe-N-mebzl; N-acetyl-L-threonyl-1-formyl-D-tryptophyl-N-methyl-N-(phenylmethyl)-L-Phenylalaninamide. Grade: 98%. CAS No. 126088-92-4. Molecular formula: C35H39N5O6. Mole weight: 625.72. |  |
| FR 121196 | FR 121196 is a potential antidementia drug originated by Fujisawa. Mechanism of Action is not undefined. FR 121196 can ameliorate the impaired memory of rat in the Morris water maze. No development was reported for Cognition disorders in Japan. Uses: Cognition disorders. Synonyms: FR 121196; FR 121196; FR 121196. N-(4-acetylpiperazin-1-yl)-4-fluorobenzenesulfonamide. Grade: 98%. CAS No. 133920-65-7. Molecular formula: C12H16FN3O3S. Mole weight: 301.34. | |
| FR122047 | FR122047 (hydrochloride) is a selective and oral active inhibitor of COX-1 with an IC 50 of 28 nM. FR122047 hydrochloride has antiplatelet, analgesic and anti-inflammatory effects in vivo [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 130717-51-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103386. |  |
| FR 122047 hydrochloride | FR 122047 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 130717-51-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| FR 122047 hydrochloride | FR-122047 is a selective cyclooxygenase-1 (COX-1) inhibitor with IC50 values is 0.028μM for COX-1 and 65 μM for COX-2. FR-122047 displays 2300 fold greater selectivity towards inhibition of COX-1 over COX-2. It shows analgesic, anti-platelet and anti-inflammatory properties. No development was reported for the treatment of Pain, Rheumatoid arthritis and Thrombosis. Uses: Pain; rheumatoid arthritis; thrombosis. Synonyms: FR 122047 hydrochloride; 1-[[4,5-bis-(4-Methoxyphenyl)-2-thiazolyl]carbonyl]-4-methylpiperazine hydrochloride. Grade: >98 %. CAS No. 130717-51-0. Molecular formula: C23H25N3O3S.HCl. Mole weight: 459.99. | |
| FR 122047 hydrochloride | ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. |  |
| FR122047 hydrochloride hydrate | FR122047 is a selective inhibitor of COX-1 with an IC50 value of 0.028 μM. Synonyms: 1-[[4,5-bis(4-methoxyphenyl)-2-thiazolyl]carbonyl]-4-methyl-piperazine, monohydrochloride, monohydrate. Grade: ≥98%. Molecular formula: C23H25N3O3S·HCl·H2O. Mole weight: 478. | |
| FR 139317 | FR 139317 is a selective Endothelin A receptor antagonist originated by Fujisawa. (Ki values are 1 nM and 7.3 μM at ETA and ETB subtypes respectively). No development was reported for the treatment of Cerebrovascular disorders, Coronary disorders, Diabetic nephropathies, Heart failure, Hypertension, Ischaemic heart disorders, Myocardial infarction and Renal failure. Uses: Cerebrovascular disorders; coronary disorders; diabetic nephropathies; heart failure; hypertension; ischaemic heart disorders; myocardial infarction; renal failure. Synonyms: FR 139317; FR139317; FR139317; PD 147953; PD147953; PD-147953; 2-((1-(Hexahydro-1H-azepinyl)carbonyl)amino-4-methylpentanoyl)-3-(-(1-methyl-1H-indolyl)propionyl)amino-3-(2-pyridyl)propionic acid. Grade: 98 %. CAS No. 142375-60-8. Molecular formula: C33H44N6O5. Mole weight: 604.75. | |
| FR 139317 | FR 139317. Group: Biochemicals. Grades: Purified. CAS No. 142375-60-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| FR-167356 | FR-167356, a benzofuran derivative, has been found to be an acuolar ATPase inhibitor and could probablye be useful in studies of some lytic bone diseases. Synonyms: FR-167356; FR167356; FR 167356; UNII-XF02B1HC8R. DSSTox_CID_28148; DSSTox_RID_82712; 2,6-dichloro-N-[3-(2-hydroxypropan-2-yl)-2-methyl-1-benzofuran-7-yl]benzamide. Grade: 98%. CAS No. 174185-16-1. Molecular formula: C19H17Cl2NO3. Mole weight: 378.25. | |
| FR-167653 | FR-167653 is a p38 mitogen-activated protein kinase inhibitor, which suppresses the development of endometriosis in a murine model. FR-167653 meliorates murine bleomycin-induced pulmonary fibrosis. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: FR-167653; FR 167653; FR167653. CAS No. 158876-66-5. Molecular formula: C24H20FN5O6S. Mole weight: 525.51. | |
| FR-167653 Free base | FR-167653, a pyrazolo?triazin derivative, has been found to be a cytokine inhibitor as well as P38 mitogen-activated protein kinase inhibitor and was once studied as an anticoagulant. Synonyms: FR167653; FR-167653; FR 167653; 1,?2-Ethanedione, 1-[7-(4-fluorophenyl)?-3,?4-dihydro-8-(4-pyridinyl)?pyrazolo[5,?1-c]?[1,?2,?4]?triazin-2(1H)?-yl]?-2-phenyl-. Grade: 98%. CAS No. 158876-65-4. Molecular formula: C24H18FN5O2. Mole weight: 427.43. | |
| FR-168888 | FR-168888, a guanidine compound, has been found to be a sodium hydrogen antiporter inhibitor that was once studied in myocardial ischaemia therapy. Synonyms: FR-168888; FR 168888; FR168888; Benzamide, N-(aminoiminomethyl)-3-(hydroxymethyl)-5-(1H-pyrrol-1-yl)-, methanesulfonate (1:1). Grade: 98%. CAS No. 168620-46-0. Molecular formula: C14H18N4O5S. Mole weight: 354.38. | |
| FR-168888 Free Base | The free base of FR-168888, a guanidine compound, has been found to be a sodium hydrogen antiporter inhibitor that was once studied in myocardial ischaemia therapy. Synonyms: FR-168888 free base; FR 168888 free base; FR168888 free base; SCHEMBL1388039; SCHEMBL8300855; Benzamide, N-(aminoiminomethyl)-3-(hydroxymethyl)-5-(1H-pyrrol-1-yl)-. Grade: 98%. CAS No. 168620-45-9. Molecular formula: C13H14N4O2. Mole weight: 258.28. | |
| FR 171113 | FR 171113 is a protease-activated receptor 1 (PAR1) antagonist displaying significant antiplatelet activity in vitro. It inhibits thrombin TRAP-6-induced platelet aggregation (IC50 = 2.5 μM) with no effect on coagulation time. Synonyms: FR 171113; FR171113; FR-171113; 2-[3-(4-Chlorophenyl)-2-[(2,4-dichlorobenzoyl)imino]-4-oxo-5-thiazolidinylidene]-acetic acid methyl ester. Grade: ≥98% by HPLC. CAS No. 173904-50-2. Molecular formula: C19H11Cl3N2O4S. Mole weight: 469.73. | |
| FR 171113 | FR 171113. Group: Biochemicals. Grades: Purified. CAS No. 173904-50-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| FR-171113 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| FR 179642 | FR 179642 is an impurity of Micafungin, which is an antifungal agent. Synonyms: FR-179642; FR179642; Pneumocandin M1; 1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0; 1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]-4-[(S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0; CMICA; FR 133303. Grade: ≥95%. CAS No. 168110-44-9. Molecular formula: C35H52N8O20S. Mole weight: 936.89. | |
| FR-179642 | FR-179642 is a cyclic peptide and an important intermediate in producing micafungin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: FR-133303; FR 133303; FR133303; FR-179642; FR 179642; FR179642; Micafungin FR-179642 impurity; Pneumocandin M1. Product Category: Others. Appearance: Solid powder. CAS No. 168110-44-9. Molecular formula: C35H52N8O20S. Mole weight: 936.9. Purity: >98%. IUPACName: 5-((1S,2S)-2-((2R,6S,9S,11R,12R,14aS,15S,16S,20S,23S,25aS)-9-amino-20-((R)-3-amino-1-hydroxy-3-oxopropyl)-2,11,12,15-tetrahydroxy-6-((R)-1-hydroxyethyl)-16-methyl-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-23-yl)-1,2-dihydroxyethyl)-2-hydroxyphenyl hydrogen sulfate. Canonical SMILES: C[C@@H](O)[C@@H]1NC(=O)[C@@H](N)C[C@@H](O)[C@@H](O)NC(=O)[C@@H]2[C@@H](O)[C@@H](C)CN2C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]3C[C@@H](O)CN3C1=O)[C@H](O)[C@@H](O)c4ccc(O)c(OS(=O)(=O)O)c4)[C@H](O)CC(=O)N. Product ID: ACM168110449. Alfa Chemistry ISO 9001:2015 Certified. |  |
| FR-179642 | FR-179642. Group: Biochemicals. Grades: Highly Purified. CAS No. 168110-44-9. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C35H52N8O20S. US Biological Life Sciences. | Worldwide |
| FR180204 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| FR 180204 | FR180204 is a novel and selective inhibitor of extracellular signal-regulated kinase (ERK), which may be a potential new therapy for rheumatoid arthritis.FR180204 showed activity to inhibit ERKs (IC50 values are 0.14 and 0.31 μM for ERK2 and ERK1 respectively). Synonyms: 865362-74-9; FR 180204; FR-180204; ERK inhibitor II; 5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE; 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-2H-pyrazolo[3,4-c]pyridazin-3-amine; 4C7X7GV82C; CHEMBL259551; 1H-Pyrazolo(3,4-C)pyridazin-3-amine, 5-(2-phenylpyrazolo(1,5-a)pyridin-3-yl)-; 5-(2-Phenylpyrazolo(1,5-a)pyridin-3-yl)-2H-pyrazolo(3,4-C)pyridazin-3-amine; 5-{2-phenyl. Grade: 0.98. CAS No. 865362-74-9. Molecular formula: C9H11N5O4. Mole weight: 253.22. | |
| FR 180204 | FR 180204. Group: Biochemicals. Grades: Purified. CAS No. 865362-74-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| FR 180204 | FR 180204 is an ATP-competitive and selective ERK inhibitor. FR 180204 inhibits ERK1 and ERK2 with IC 50 s of 0.51 μM ( K i =0.31 μM) and 0.33 μM ( K i =0.14 μM), respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 865362-74-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12275. | |
| FR-181074 | FR-181074 may be a bio-active chemical to treat Male Sexual Dysfunction. Synonyms: 1-[(2-chlorophenyl)methyl]-3-(2-methylpropanoyl)-2-propylindole-6-carboxamide; FR-181074; FR181074; FR 181074; UNII-D3C5RV093V. Grade: >98%. CAS No. 184147-65-7. Molecular formula: C23H25ClN2O2. Mole weight: 396.91. | |
| FR-181157 | FR-181157, an oxazol derivative, has been found to be a prostaglandin mimetic and could have potential biological activities as a IP receptor agonist. Synonyms: FR-181157; FR 181157; FR181157; FR-181157 Free Base. (S)-FR-181157; SCHEMBL8057380; sodium; 2-[3-[[(1S)-2-(4,5-diphenyl-1,3-oxazol-2-yl)cyclohex-2-en-1-yl]methyl]phenoxy]acetate. Grade: 98%. CAS No. 171046-15-4. Molecular formula: C30H26NNaO4. Mole weight: 487.52. | |
| FR-181157 Free base | FR-181157 is an orally active prostacyclin mimetic that shows high potency and agonist efficacy at the IP receptor. Synonyms: sodium; 2-[3-[[(1S)-2-(4,5-diphenyl-1,3-oxazol-2-yl)cyclohex-2-en-1-yl]methyl]phenoxy]acetate; FR 181157; FR181157; 200433-03-0 (FR-181157 Free Base). Grade: >98%. CAS No. 200433-03-0. Molecular formula: C30H26NNaO4. Mole weight: 487.52. | |
| FR-181877 | FR-181877, an oxopyridazin derivative, has been found to be a nonprostanoid PGI2 agonist and could restrain the aggregation of human platelets induced by ADP. IC50: 0.081μM. Synonyms: FR-181877; FR 181877; FR181877. (-)-FR-181877; 2-[[(6S)-6-[(3-benzhydryl-6-oxopyridazin-1-yl)methyl]-5,6,7,8-tetrahydronaphthalen-1-yl]oxy]acetic acid. Grade: 98%. CAS No. 172936-99-1. Molecular formula: C30H28N2O4. Mole weight: 480.56. | |
| FR-182024 | FR-182024, an azabicyclo derivative, has been found to have potential activity as an anti-Helicobacter pylori agent and was once stuied against helicobacter infections. Synonyms: FR-182024; FR 182024; FR182024. 9031SV3FWE; (6R,7R)-3-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]-8-oxo-7-[(2-phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. Grade: 98%. CAS No. 179034-83-4. Molecular formula: C18H16N4O4S3. Mole weight: 448.53. | |
| FR-182877 | FR-182877 is produced by the strain of Streptomyces sp. No. 9885. It has a strong effect on rat ascites and solid tumors in vivo, and has no antibacterial activity. Molecular formula: C24H32O5. Mole weight: 400.51. | |
| FR-182980 | FR-182980, a pyridine derivative, has been found to be a sterol O-acyltransferase inhibitor and was once studied in hypercholesterolaemia. Synonyms: FR-182980; FR182980; FR 182980; 1-cycloheptyl-1-[[4-(4-fluorophenoxy)phenyl]methyl]-3-[6-methyl-2,4-bis(methylsulfanyl)pyridin-3-yl]urea. Grade: 98%. CAS No. 179054-51-4. Molecular formula: C29H34FN3O2S2. Mole weight: 539.73. | |
| FR183998 | FR183998 is a Na+/H+ exchanger inhibitor. Inhibition of the Na+/H+ exchanger improves heart and brain injuries induced by I/R. Synonyms: FR-183998. Grade: 98%. CAS No. 239440-20-1. Molecular formula: C17H19Cl2N5O2S. Mole weight: 428.34. | |
| FR-186054 | FR-186054, a pyridine derivative, has been found to be a sterol O-acyltransferase inhibitor and was once studied in hyperlipidaemia. Synonyms: FR-186054; FR 186054; FR186054; 1-benzyl-3-[6-methyl-2,4-bis(methylsulfanyl)pyridin-3-yl]-1-[[3-(1H-pyrazol-5-yl)phenyl]methyl]urea. Grade: 98%. CAS No. 179053-90-8. Molecular formula: C26H27N5OS2. Mole weight: 489.66. | |
| FR-188582 | FR-188582, with anti-inflammatory and ulcerogenic properties, is a highly selective inhibitor of COX-2 with IC50=0.017 microM. Synonyms: 3-chloro-5-(4-methylsulfonylphenyl)-1-phenylpyrazole; FR 188582; FR188582; FR-188582. Grade: >98%. CAS No. 189699-82-9. Molecular formula: C16H13ClN2O2S. Mole weight: 332.8. | |
| FR-190809 | FR-190809 is a potent and orally efficacious ACAT inhibitor potentially for the treatment of Lipoprotein Disorders. Synonyms: 1-cycloheptyl-1-[[4-(4-fluorophenoxy)phenyl]methyl]-3-[6-methyl-2,4-bis(methylsulfonyl)pyridin-3-yl]urea; FR-190809; FR 190809; FR190809.N-cycloheptyl-N-(4-(4-fluorophenoxy)-benzyl)-N'-(2,4-bis(methylsulfonyl)-6-methylpyridin-3-yl)urea. Grade: >98%. CAS No. 215589-63-2. Molecular formula: C29H34FN3O6S2. Mole weight: 603.73. | |
| FR-191512 | It is a polyphenolic compound with anti-influenza A virus effect. Synonyms: FR191512. Molecular formula: C38H38O16. Mole weight: 750.70. | |
| FR-193262 | FR-193262 is a designed prostacyclin mimetic without PG skeleton which exhibits potent PGI2 agonistic activity with good selectivity for IP receptor and bioavailability. Synonyms: FR-193262; FR 193262; FR193262; sodium; 2-[[(5R)-5-[(2R)-2-(4,5-diphenyl-1,3-oxazol-2-yl)pyrrolidin-1-yl]-5,6,7,8-tetrahydronaphthalen-1-yl]oxy]acetate; FR-193262; 187992-22-9(FR-193262); 314289-63-9 (FR-193262 Free Base). Grade: >98%. CAS No. 187992-22-9. Molecular formula: C31H29N2NaO4. Mole weight: 516.56. | |
| FR-193262 Free base | A bio-active organic chemical. Uses: A bio-active organic chemical. Synonyms: FR-193262; FR 193262; FR193262; 2-[[(5R)-5-[(2R)-2-(4,5-diphenyl-1,3-oxazol-2-yl)pyrrolidin-1-yl]-5,6,7,8-tetrahydronaphthalen-1-yl]oxy]acetic acid. Grade: ≥98%. CAS No. 314289-63-9. Molecular formula: C31H30N2O4. Mole weight: 494.59. | |
| FR-193879 | FR-193879, a cephem derivative, is an efficacious anti-Helicobacter pylori cephalosporin. Synonyms: (6R,7R)-3-[[4-(2-amino-2-oxoethyl)-1,3-thiazol-2-yl]sulfanyl]-8-oxo-7-[(2-phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; FR-193879; FR193879; FR 193879. Grade: >98%. CAS No. 194928-82-0. Molecular formula: C20H18N4O5S3. Mole weight: 490.58. | |
| FR194921 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| FR-194921 | FR-194921 is a potent, selective and orally active antagonist for central adenosine A1 receptors that displays high affinity and selectivity for the adenosine A1 receptor (Ki= 2.9 nM) and did not show species differences in binding affinity. Synonyms: 2-(1-methylpiperidin-4-yl)-6-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)pyridazin-3-one; FR-194921; FR 194921; FR194921; 2-(1-methyl-4-piperidinyl)-6-(2-phenylpyrazolo(1,5-a)pyridin-3-yl)-3(2H)-pyridazinone. Grade: >98%. CAS No. 202646-80-8. Molecular formula: C23H23N5O. Mole weight: 385.46. | |
| FR198248 | FR-198248, a new type of hydroxyl benzaldehyde compound, was isolated from the cultured broth of a fungal strain identified as Aspergillus terreus from morphological characteristics. FR-198248 exhibited anti-influenza virus activity in Madin-Darby canine kidney (MDCK) cells in vitro. Synonyms: FR-198248; 1,5,6,7-Isobenzofurantetrol, 1,3-dihydro-4-methyl-; 197316-54-4; 1-O-Demethyl-FR-202306; 6ZL0C9ER7N; 2,3,4-trihydroxy-6-(hydroxymethyl)-5-methylbenzaldehyde; 364342-83-6; UNII-6ZL0C9ER7N; SCHEMBL1527081; Q27265782. Grade: >98%. CAS No. 197316-54-4. Molecular formula: C9H10O5. Mole weight: 198.17. | |
| FR-202306 | FR-202306 is a synthetic peptide deformylase (PDF) inhibitor. Uses: Peptide deformylase (pdf) inhibitor. Synonyms: FR-202306; FR 202306; FR202306. 3-methoxy-7-methyl-1,3-dihydro-2-benzofuran-4,5,6-triol. Grade: ≥98%. CAS No. 342785-41-5. Molecular formula: C10H12O5. Mole weight: 212.20. | |
| FR-217840 | FR-217840 is a matrix metalloproteinase inhibitor. It can suppress joint destruction. FR217840 may have potential as a novel anti-rheumatic drug. Uses: Anti-rheumatic agent. Synonyms: FR-217840; FR217840; FR 217840. (2S)-1-((5-(4-fluorophenyl)-2-thienyl)sulfonyl)-N-hydroxy-4-(methylsulfonyl)-2-Piperazinecarboxamide. Grade: 98%. CAS No. 848444-16-6. Molecular formula: C16H18FN3O6S3. Mole weight: 463.52. | |
| FR-218944 | FR-218944 is a vasopressin antagonist compound. Synonyms: methanesulfonic acid; 2-methoxy-N-(2-methyl-1H-benzimidazol-4-yl)-4-(2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)benzamide; FR-218944; FR 218944; FR218944. Grade: >98%. CAS No. 233264-02-3. Molecular formula: C28H30N4O6S. Mole weight: 550.63. | |
| FR-221647 | FR-221647 is a non-nucleoside adenosine deaminase inhibitor. Synonyms: 1-(1-hydroxy-4-phenylbutan-2-yl)imidazole-4-carboxamide; FR-221647; FR 221647; FR221647. Grade: >98%. CAS No. 256461-28-6. Molecular formula: C14H17N3O2. Mole weight: 259.3. | |
| FR225659 | FR225659 is originally isolated from Helicomyces sp. No. 19353. It can suppress the gluconeogenesis induced by Glucagon in Primary hepatocytes of rats. Molecular formula: C36H42ClN7O8. Mole weight: 736.21. | |
| FR-229934 | FR-229934 is a Type 5 cyclic nucleotide phosphodiesterase inhibitor. In Feb 2008, preclinical for Erectile dysfunction in Japan was discontinued. Uses: Erectile dysfunction. Synonyms: FR-229934; FR229934; FR 229934. 1-((3,4-dichlorophenyl)methyl)-2-methyl-N-(pentylsulfonyl)-1H-Benzimidazole-6-carboxamide. Grade: 98%. CAS No. 799841-02-4. Molecular formula: C21H23Cl2N3O3S. Mole weight: 468.40. | |
| FR-234938 | FR-234938, with anti-inflammatory property, is a non-nucleoside recombinant human adenosine deaminase enzyme inhibitor. Synonyms: 1-[(3R,4S)-4-hydroxy-1-naphthalen-1-ylpentan-3-yl]imidazole-4-carboxamide; FR-234938; FR 234938; FR234938. Grade: >98%. CAS No. 256461-79-7. Molecular formula: C19H21N3O2. Mole weight: 323.39. | |
| FR-235222 | FR-235222 is an immunosuppressive substance that inhibits mammalian histone deacetylase (HDAC). It is produced by the strain of Acremonium sp. No. 27082. Synonyms: FR 235222; FR235222. Molecular formula: C30H44N4O6. Mole weight: 556.69. | |
| FR236913 | FR236913 is a compoundused in studying chronic lymphocytic leukemia (CLL) and other hematologic malignancies. This targeted therapy inhibits Bruton's tyrosine kinase (BTK) is a key enzyme in the B-cell receptor signaling pathway. By disrupting abnormal B-cell signaling, FR236913 helps control the progression of CLL. Synonyms: 1-[(2R)-4-{6-[(Benzylcarbamoyl)amino]-1H-indol-1-yl}-1-hydroxybutan-2-yl]-1H-imidazole-4-carboxamide. Molecular formula: C24H26N6O3. Mole weight: 446.5. | |
| FR 236924 | FR 236924 is a selective PKCε activator with > 7-fold selectivity over other PKC isozymes. FR 236924 promotes glutamate release via presynaptic α7 nicotinic receptors on glutamatergic terminals in vitro and enhances cognition in vivo. It has the potential for the treatment of Alzheimer disease. Synonyms: FR 236924; FR236924; FR-236924; Dcp-LA; 2-[(2-Pentylcyclopropyl)methyl]cyclopropaneoctanoic acid. Grade: ≥99% by HPLC. CAS No. 28399-31-7. Molecular formula: C20H36O2. Mole weight: 308.5. | |
| FR 236924 | FR 236924. Group: Biochemicals. Grades: Purified. CAS No. 28399-31-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| FR-245 | FR-245. Group: Polymers. CAS No. 25713-60-4. Product ID: 2,4,6-tris(2,4,6-tribromophenoxy)-1,3,5-triazine. Molecular formula: 1067.4g/mol. Mole weight: C21H6Br9N3O3. C1=C (C=C (C (=C1Br)OC2=NC (=NC (=N2)OC3=C (C=C (C=C3Br)Br)Br)OC4=C (C=C (C=C4Br)Br)Br)Br)Br. InChI=1S/C21H6Br9N3O3/c22-7-1-10 (25)16 (11 (26)2-7)34-19-31-20 (35-17-12 (27)3-8 (23)4-13 (17)28)33-21 (32-19)36-18-14 (29)5-9 (24)6-15 (18)30/h1-6H. BDFBPPCACYFGFA-UHFFFAOYSA-N. |  |
| FR252384 | FR252384 is novel potent antagonists of human neuropeptide Y-Y5 receptor (IC50= 2.3 nM). Synonyms: FR252384; FR 252384; FR-252384; 9-methyl-2-pyridin-3-yl-3,4,5,6-tetrahydrobenzo[2,3]cyclohepta[2,4-b]imidazole; Benzo[3,4]cyclohept[1,2-d]imidazole, 1,4,5,6-tetrahydro-9-methyl-2-(3-pyridinyl)-. CAS No. 447405-11-0. Molecular formula: C18H17N3. Mole weight: 275.35. | |
| FR 252921 | FR 252921 is produced by the strain of Pseudomonas fluorenscens No. 408813. It shows immunosuppressive effect in mice in vivo and in vitro, and has synergistic effect with FK-506. Molecular formula: C29H44N2O5. Mole weight: 500.67. | |
| FR-252922 | FR-252922 is produced by the strain of Pseudomonas fluorenscens No. 408813. It shows immunosuppressive effect in mice in vivo and in vitro, and has synergistic effect with FK-506. Molecular formula: C31H48N2O5. Mole weight: 528.72. | |
| FR-29038 | It is originally isolated from Nocardia uniformis subsp. tsuyamanensis. FR-29038 has anti-Bacillus, Escherichia, Klebsiella, Pseudomonas, Salmonella, Shigella and other family bacteria activities. Synonyms: Antibiotic FR 29038; BRN 3578863; O-{4-[1-Amino-2-({1-[carboxy(4-hydroxyphenyl)methyl]-2-oxoazetidin-3-yl}imino)-2-hydroxyethyl]phenyl}homoserine. CAS No. 59511-12-5. Molecular formula: C23H26N4O8. Mole weight: 486.47. | |
| FR295389 free base | FR295389 free base is a new cephalosporin. It shows effective in vitro antibacterial activity against metallo-beta-lactamase (MBL)-producers. Uses: Fr295389 free base has effective antibacterial activity. Synonyms: FR-295389 free base; FR 295389 free base; FR295389 free base; (6R,7R)-3-[[7-[3-aminopropyl(carbamimidoyl)amino]-2,3-dihydroimidazo[1,2-b]pyrazol-5-yl]methyl]-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(2-carboxypropan-2-yloxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. Grade: >98 %. CAS No. 1019207-71-6. Molecular formula: C25H33N13O7S2. Mole weight: 691.74. | |
| FR295389 sulfuric acid | FR295389 sulfuric acid is the sulfate form of FR295389, which is a new cephalosporin. It has effective in vitro antibacterial activity against metallo-beta-lactamase (MBL)-producers. Uses: Fr295389 sulfuric acid has effective antibacterial activity. Synonyms: FR-295389 sulfuric acid; FR 295389 sulfuric acid; FR295389 sulfuric acid; (6R,7R)-3-[[7-[3-aminopropyl(carbamimidoyl)amino]-2,3-dihydroimidazo[1,2-b]pyrazol-5-yl]methyl]-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(2-carboxypropan-2-yloxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sulfuric acid. Grade: >98 %. CAS No. 1019207-72-7. Molecular formula: C25H35N13O11S3. Mole weight: 789.81. | |
| FR 32863 | FR 32863 is produced by the strain of Streptomyces lavendulae 8006. FR 32863 has anti-gram-positive and anti-gram-negative activities. Synonyms: Antibiotic FR 32863; Antibiotic FR 900136; BRN 2092108; FR-32863; (E)-(3-(Formylhydroxyamino)-1-propenyl)phosphonic acid. CAS No. 66508-88-1. Molecular formula: C4H8NO5P. Mole weight: 181.08. | |
| FR-33289 | FR-33289 is produced by the strain of Streptomyces rubellomurinus subsp. indigoferus 24. FR-33289 has anti-gram-positive and anti-gram-negative activities. Synonyms: Antibiotic FR 33289; (R)-(3-(Acetylhydroxyamino)-2-hydroxypropyl)phosphonic acid. CAS No. 73240-15-0. Molecular formula: C5H12NO6P. Mole weight: 213.13. | |
| FR-62765 | FR-62765, a derivative of WF-3681, is a novel aldose reductase inhibitor. It might be a useful drug for diabetic neuropathy. Uses: Fr-62765 might be a useful drug for diabetic neuropathy. Synonyms: FR 62765; FR-62765; FR62765. 2-Furanpropanoic acid, 2,5-dihydro-4-methoxy-5-oxo-3-phenyl-, ethyl ester; FR62765; 2,5-Dihydro-4-methoxy-5-oxo-3-phenylfuran-2-propanoic acid ethyl ester; Ethyl 2,5-dihydro-4-methoxy-5-oxo-3-phenyl-2-furanpropanoate; Ethyl 3-(4-methoxy-5-oxo-3-phenyl-2H-furan-2-yl)propanoate. Grade: >98 %. CAS No. 105346-34-7. Molecular formula: C16H18O5. Mole weight: 290.31. | |
| FR-64822 | FR-64822 is a novel non-opioid antinociceptive compound. It has antinociceptive activities in a variety of assays in mice and rats. It also has a strong antinociceptive activity in the acetic acid writhing test. Uses: Fr-64822 has antinociceptive activities. Synonyms: FR 64822; FR64822; FR-64822. N-(4-Pyridylcarbamoyl)amino 1,2,3,6-tetrahydropyridine; 1-(3,6-dihydro-2H-pyridin-1-yl)-3-pyridin-4-ylurea; FR64822. Grade: >98 %. CAS No. 102671-35-2. Molecular formula: C11H14N4O. Mole weight: 218.26. | |
| FR 65814 | FR 65814 is originally isolated from Penicillum jensenii F-2883. It has a strong immunosuppressive effect, and the IC50 of inhibiting mixed lymphocyte reaction (MLR) in mice is 34 nmol/L. Synonyms: 4-(2-Methyl-3-(3-methyl-2-butenyl)oxiranyl)-1-oxaspiro(2.5)octane-5,6-diol. CAS No. 103470-60-6. Molecular formula: C15H24O4. Mole weight: 268.35. | |
| FR 66979 | FR 66979 is produced by the strain of Streptomyces sandaensis No. 6897. It has inhibitory activity against tumor cells, including leukemia P388 cells and melanoma B16 cells. Synonyms: [7,9-Dihydroxy-5-(hydroxymethyl)-1,1a,2,8,9,9a-hexahydro-3,9-epoxyazireno[2,3-c][1]benzazocin-8-yl]methyl hydrogen carbonimidate. Grade: 97%. CAS No. 102409-60-9. Molecular formula: C14H17N3O6. Mole weight: 323.30. | |
| FR 75513 | FR 75513 is a 1,1'-biphenyl-2,6-dicarboxylic acid diester compound with inhibitory activity on guinea-pig detrusor muscle contraction at electrical field stimulation in vitro. IC 50 value is 3.3 x 10(-6) g/ml. Synonyms: FR 75513; FR75513; FR-75513. 3-O-methyl 1-O-propan-2-yl 4-hydroxy-6-methyl-2-(2-nitrophenyl)benzene-1,3-dicarboxylate. Grade: 98%. CAS No. 127975-78-4. Molecular formula: C19H19NO7. Mole weight: 373.36. | |
| FR 76830 | This molecular is developed as a novel bradycardiac agent through organic synthesis. Uses: Bradycardiac agent. Synonyms: FR 76830; FR-76830; FR76830. 2-methyl-N-(4-morpholinylethyl)-4-(3-nitrophenyl)-6-phenyl- 3-Pyridinecarboxamide. Grade: 98%. CAS No. 113243-75-7. Molecular formula: C25H26N4O4. Mole weight: 446.5. | |
| FR-78844 | FR-78844 is used as a bone resorption antagonist. Uses: Fr-78844 is used as a bone resorption antagonist. Synonyms: FR 78844; FR78844; FR-78844; Disodium phenylthiocarbamoylmethylenediphosphonate; (2-(Phenylamino)-2-thioxoethylidene)bisphosphonic acid disodium salt; Disodium [2-anilino-1-[hydroxy(oxido)phosphoryl]-2-sulfanylideneethyl]-hydroxyphosphinate; FR78844; Phosphonic acid, (2-(phenylamino)-2-thioxoethylidene)bis-, disodium salt. Grade: >98%. CAS No. 112856-39-0. Molecular formula: C8H9NNa2O6P2S. Mole weight: 355.15. | |
| FR-900098 | FR-900098 is produced by the strain of Streptomyces rubellomurinus subsp. indigoferus 24. FR-900098 has anti-gram-positive and anti-gram-negative activities. Synonyms: Antibiotic FR-900098; FR 900098; BRN 2096083; 3-(N-acetyl-N-hydroxy)aminopropylphosphonic acid. Grade: >98%. CAS No. 66508-32-5. Molecular formula: C5H12NO5P. Mole weight: 197.13. | |
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