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| Product | Description | |
|---|---|---|
| Fructosyl-Amino Acid Oxidase from E. coli, Recombinant | Fructosamines are formed when glucose is condensed amino group of amino acids or proteins. Fructosamine oxidases (FAOX) catalyze the oxidative deglycation of low molecular weight fructosamines. Fructosyl amino acid oxidase catalyzes the oxidation of the C-N bond linking the C1 of the fructosyl moiety and the nitrogen of the amino group of fructosyl amino acids. Group: Enzymes. Synonyms: Fructosyl-amino acid oxidase. Fructosyl-amino acid oxidase. Mole weight: ca. 45 kDa. Activity: > 4 U/mg lyophilizate. Appearance: Yellow lyophilizate. Storage: at -20°C. Source: E. coli. Species: E. coli. Fructosyl-L-amino acid : oxygen oxidoreductase; EC 1.5.3.; Fructosyl-amino acid oxidase. Cat No: DIA-409. |  |
| Fructosyl-amino acid oxidase from Microorganism | Fructosyl-amino acid oxidase from Microorganism. Group: Enzymes. Synonyms: Fructosyl-amino acid oxidase From Microorganism. Fructosyl-amino acid oxidase. Mole weight: approx. 48,000Da (by SDS-PAGE). Activity: 3.0U/mg-solid or more. Appearance: Yelowish amorphous powder,lyophilized. Source: Microorganism. Fructosyl-amino acid oxidase. Cat No: DIA-274. | |
| Fructosyl Glycine α/β Mixture (Mixture of Diastereomers) | Fructosyl Glycine is a synthetic glycoamine used in the study of glycoamine analogs and their effect on metastatic carcinoma cells. Synonyms: N-(1-Deoxy-β-D-fructopyranos-1-yl)glycine; 1-[(Carboxymethyl)amino]-1-deoxy-β-D-fructopyranose. CAS No. 60644-20-4. Molecular formula: C8H15NO7. Mole weight: 237.21. |  |
| Fructosyl-lysine | Fructosyl-lysine is an indispensable compound, holding immense value for evaluating glycation. Glycation is a fundamental process intricately linked to multifarious ailments including diabetes, alzheimer's and aging. Synonyms: Fructosyllysine; fructoselysine; Fructose lysine; epsilon-Fructoselysine; epsilon-fructosyl-L-lysine; N(6)-(1-deoxy-D-fructos-1-yl)-L-lysine; L-Lysine, N6-(1-deoxy-D-fructos-1-yl)-; 1-{[(5S)-5-amino-5-carboxypentyl]amino}-1-deoxy-D-fructose; N6-((3S,4R,5R)-3,4,5,6-tetrahydroxy-2-oxohexyl)-L-lysine; N6-(D-fructosyl)-L-lysine; epsilon-N-deoxyfructosyllysine; 1-deoxy-1-(epsilon-N-L-lysino)-D-fructose. CAS No. 21291-40-7. Molecular formula: C12H24N2O7. Mole weight: 308.33. | |
| Fructosyl-lysine | Fructosyl-lysine (Fructoselysine) is an amadori glycation product from the reaction of glucose and lysine by the Maillard reaction. Fructosyl-lysine is the precursor to glucosepane, a lysine - arginine protein cross-link that can be an indicator in diabetes detection [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Fructoselysine. CAS No. 21291-40-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129380. |  |
| Fructosyl-lysine dihydrochloride | Fructosyl-lysine (Fructoselysine) dihydrochloride is an amadori glycation product from the reaction of glucose and lysine by the Maillard reaction. Fructosyl-lysine dihydrochloride is the precursor to glucosepane, a lysine - arginine protein cross-link that can be an indicator in diabetes detection [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Fructoselysine dihydrochloride. CAS No. 96192-35-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129380A. | |
| Fructosyl-peptide Oxidase from E. coli, Recombinant | The fructosyl peptide oxidase is an enzyme that catalyzes the reaction which produces a sugar osone (an α-keto aldehyde), a peptide, and hydrogen peroxide by oxidative cleaving, in the presence of oxygen molecules, the C--N bond in the ketose derivative produced by Amadori rearrangement of glucosylamine produced by the reaction between the hemiacetal of glucose and the N-terminal amino group of a peptide. Group: Enzymes. Synonyms: Fructosyl-peptide : oxygen oxidoreductase; EC 1.5.3; Fructosyl-peptide Oxidase. Enzyme Commission Number: EC 1.5.3. Fructosyl-peptide Oxidase. Mole weight: ca. 60 kDa. Activity: > 4 U/mg lyophilizate. Stability: Stable at 37°C for at least one month. Appearance: Yellow lyophilizate. Storage: at -20°C. Source: E. coli. Species: E. coli. Fructosyl-peptide : oxygen oxidoreductase; EC 1.5.3; Fructosyl-peptide Oxidase. Cat No: DIA-410. | |
| Fructosyltransferase 68A from Bacillus subtilis, Recombinant | Levansucrase (EC 2.4.1.10) is an enzyme that catalyzes the chemical reaction: sucrose + (2,6-beta-D-fructosyl)n ? glucose + (2,6-beta-D-fructosyl)n+1. Thus, the two substrates of this enzyme are sucrose and (2,6-beta-D-fructosyl)n, whereas its two products are glucose and (2,6-beta-D-fructosyl)n+1. This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. Group: Enzymes. Synonyms: Levansucrase; EC 2.4.1.10; sucrose:2,6-beta-D-fructan 6-beta-D-fructosyltransferase; sucrose 6-fructosyltransferase; beta-2,6-fructosyltransferase; beta-2,6-fructan:D-glucose 1-fructosyltransferase. Enzyme Commission Number: EC 2.4.1.10. CAS No. 9030-17-5. Purity: >90% by SDS-PAGE. Levansucrase. Mole weight: 52.0 kDa. Storage: This enzyme is shipped at room temperature but should be stored at -20 °C. Form: 35 mM NaHepes buffer, pH 7.5, 750 mM NaCl, 200 mM imidazol, 3.5 mM CaCl2, 0.02% sodium azide and 25% (v/v) glycerol. Source: E. coli. Species: Bacillus subtilis. Levansucrase; EC 2.4.1.10; sucrose:2,6-beta-D-fructan 6-beta-D-fructosyltransferase; sucrose 6-fructosyltransferase; beta-2,6-fructosyltransferase; beta-2,6-fructan:D-glucose 1-fructosyltransferase; Fructosyltransferase 68A. Cat No: NATE-1384. | |
| fructuronate reductase | Also reduces D-tagaturonate. Group: Enzymes. Synonyms: mannonate oxidoreductase; mannonic dehydrogenase; D-mannonate dehydrogenase; D-mannonate:NAD oxidoreductase. Enzyme Commission Number: EC 1.1.1.57. CAS No. 9028-44-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0342; fructuronate reductase; EC 1.1.1.57; 9028-44-8; mannonate oxidoreductase; mannonic dehydrogenase; D-mannonate dehydrogenase; D-mannonate:NAD oxidoreductase. Cat No: EXWM-0342. | |
| Fructus Gardeniae Extract (Standard) | Fructus Gardeniae Extract (Standard). Applications: For the upset, jaundice, blood heat spit bleed at the nose, sprains, edema. Group: Others. Synonyms: Fructus Gardeniae Extract (Standard). Purity: 10%,10:1, HPLC. Appearance: Red-brown powder. Storage: 24 months with original packing under 18°C. Store in cool dry place,avoid sunlight and high temperature. Source: Rubiaceae Gardenia fruit. Fructus Gardeniae Extract (Standard) ; plant extract. Pack: 1kg, 5kg, 10kg aluminum foil vacuum bag; or 20kg, 25kg Fiber Drum. Cat No: EXTW-201. | |
| fruit bromelain | From the pineapple plant, Ananas comosus. Scarcely inhibited by chicken cystatin. Another cysteine endopeptidase, with similar action on small molecule substrates, pinguinain, is obtained from the related plant, Bromelia pinguin, but pinguinain differs from fruit bromelain in being inhibited by chicken cystatin. Group: Enzymes. Synonyms: juice bromelain; ananase; bromelase; bromelin; extranase; juice bromelain; pinase; pineapple enzyme; traumanase; fruit bromelain FA2. Enzyme Commission Number: EC 3.4.22.33. CAS No. 9001-00-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4208; fruit bromelain; EC 3.4.22.33; 9001-00-7; juice bromelain; ananase; bromelase; bromelin; extranase; juice bromelain; pinase; pineapple enzyme; traumanase; fruit bromelain FA2. Cat No: EXWM-4208. | |
| Fruit fiber mask | Fruit fiber mask. Product ID: CDC10-0635. Category: Classic Mask. Product Keywords: Cosmetic Ingredients; Cosmetic packaging material; Fruit fiber mask; CDC10-0635; Classic Mask; Wood pulp fibers. |  |
| Fruit fiber mask | Fruit fiber mask. Product ID: CDC10-0696. Category: Cosmetic Packaging Material. Product Keywords: Cosmetic Ingredients; Mask; CDC10-0696; Fruit fiber mask; Cosmetic Packaging Material;. | |
| Frunevetmab | Frunevetmab (NV-02) is a felinized anti- nerve growth factor (NGF) monoclonal antibody with a K d of 20 pM. Frunevetmab can effectively decrease osteoarthritis (OA) pain in cats [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: NV-02. CAS No. 1708936-80-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99627. | |
| Fruquintinib | Fruquintinib, also known as HMPL-013, is an orally available, small molecule inhibitor of vascular endothelial growth factor receptors (VEGFRs), with potential anti-angiogenic and antineoplastic activities. Synonyms: Fruquintinib; HMPL013; HMPL 013; HMPL-013. Grade: 98%. CAS No. 1194506-26-7. Molecular formula: C21H19N3O5. Mole weight: 393.39. | |
| Fruquintinib | Fruquintinib (HMPL-013) is a highly potent and selective VEGFR 1/2/3 inhibitor with IC 50 s of 33, 0.35, and 35 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HMPL-013. CAS No. 1194506-26-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19912. | |
| Frutinate | Frutinate. CAS No. 35206-51-0. VIGON Item # 502498. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers. |  America & Internationally |
| Frutinone A | Frutinone A. Group: Biochemicals. Alternative Names: 6H,7H-[1]Benzopyrano[4,3-b][1]benzopyran-6,7-dione. Grades: Highly Purified. CAS No. 38210-27-4. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C16H8O4. US Biological Life Sciences. |  Worldwide |
| Frutinone A | Frutinone A. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 6H,7H-[1]Benzopyrano[4,3-b][1]benzopyran-6,7-dione. Product Category: Heterocyclic Organic Compound. CAS No. 38210-27-4. Molecular formula: C16H8O4. Mole weight: 264.23. Purity: 0.96. IUPACName: chromeno[4,3-b]chromene-6,7-dione. Canonical SMILES: C1=CC=C2C(=C1)C3=C(C(=O)C4=CC=CC=C4O3)C(=O)O2. Density: 1.49g/cm³. Product ID: ACM38210274-1. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Frutonile | Frutonile. CAS No. 69300-15-8. VIGON Item # 503220. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers, peach nitrile, 2-METHYLDECANONITRILE. | America & Internationally |
| Frutonile | Frutonile. Group: Biochemicals. Alternative Names: 2-Methyldecanenitrile; 2-Cyanodecane. Grades: Highly Purified. CAS No. 69300-15-8. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C11H21N. US Biological Life Sciences. | Worldwide |
| Frys Reagent | Martensitic 400 series stainless steels. Group: Etchants. |  |
| FSBA hydrochloride | FSBA hydrochloride is a useful reagent for the affinity labeling of adenine nucleotide binding proteins and is mainly applied in the study of purified The labeling and subsequent detection of these proteins can be blocked by including an excess of MgATP, which competes with FSBA for nucleotidebinding sites [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 5'-p-Fluorosulfonylbenzoyladenosine. CAS No. 78859-42-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-123650. | |
| FSB - CAS 891180-93-1 | A fluorine analog of the amyloidophilic fluorescent probe BSB that crosses the blood-brain barrier and displays low toxicity. Group: Fluorescence/luminescence spectroscopy. |  |
| Fscpx | Fscpx. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Lopac-F-7927; HMS3261F15; FSCPX; FSCPX xanthine; 8-Cyclopentyl-N3-[3-(4-(fluorosulfonyl)benzoyloxy)propyl]-N1-propylxanthine. Product Category: Heterocyclic Organic Compound. CAS No. 156547-56-7. Molecular formula: C23H27FN4O6S. Mole weight: 506.55. Purity: 0.96. IUPACName: 3-(8-cyclopentyl-2,6-dioxo-1-propyl-7H-purin-3-yl)propyl 4-fluorosulfonylbenzoate. Product ID: ACM156547567. Alfa Chemistry ISO 9001:2015 Certified. Categories: FSSPX. | |
| FSCPX | FSCPX is a potent and selective irreversible antagonist of A 1 adenosine receptor (A 1 AR) , with low nanomolar potency for binding to the A 1 AR. FSCPX could modify the effect of NBTI, a nucleoside transport inhibitor, by reducing the interstitial adenosine level in the guinea pig atrium [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 156547-56-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116042. | |
| FSEN1 | FSEN1 is a potent and non-competitive FSP1 inhibitor with an IC50 value of 313 nM. FSEN1 triggers iron death in cancer cells by inhibiting FSP1. FSEN1 can be used in research of cancer[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 862808-01-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153629. | |
| FSG67 | FSG67 is a glycerol 3-phosphate acyltransferase (GPAT) inhibitor with an IC50 of 24 ?M[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1158383-34-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112489. | |
| FSK hydrochloride | FSK hydrochloride is fluorosulfonyloxybenzoyl-l-lysine, with a long and flexible aryl fluorosulfate-containing side chain that can reach protein sites that are difficult to reach by covalent linkage. FSK hydrochloride is a modified nanomolecule that targets the epidermal growth factor receptor (EGFR), creating a covalent binding that results in irreversible binding. FSK hydrochloride captures unknown enzyme-substrate interactions in living cells through genetically encoded chemical cross-linking, targeting residues beyond Cys, and cross-linking at the binding periphery. FSK hydrochloride enables the construction of bioreactive SuFEx systems for creating covalent bonds in different proteins in vitro and in vivo [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3033987-42-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-48999A. | |
| FSL-1 | FSL 1 is a TLR2/6 peptide agonist (also a putative TLR10 ligand) that activates NF-κB. FSL 1 induces the expression of some pro-inflammatory cytokines such as IL-8, IL-1β, CCL20 and TNF-α in vitro. Synonyms: FSL 1; FSL1; L-Phenylalanine, S-[2,3-bis[(1-oxohexadecyl)oxy]propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-; S-[2,3-Bis[(1-oxohexadecyl)oxy]propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-L-phenylalanine; FSL-1 lipoprotein, synthetic; Fibroblast-stimulating lipopeptide-1; Pam2-Cys-Gly-Asp-Pro-Lys-His-Pro-Lys-Ser-Phe-OH. Grade: ≥95%. CAS No. 322455-70-9. Molecular formula: C84H140N14O18S. Mole weight: 1666.16. | |
| FSL-1 | ?80% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| FSL-1-FLAG | Lipopeptide FSL-1, synthesized on the basis of the N-terminal structure of M. salivarium lipoprotein, can induce ICAM-1 expression on the surface of human gingival fibroblasts. In addition, it induces the production of monocyte chemoattractant protein 1, interleukin-6 (IL-6), and IL-8. It activates macrophages to produce tumor necrosis factor-alpha. Synonyms: Fibroblast Stimulating Lipopeptide 1 FLAG-tag; H-Cys((RS)-2,3-di(palmitoyloxy)-propyl)-Gly-Asp-Pro-Lys-His-Pro-Lys-Ser-Phe-Asp-Tyr-Lys-Asp-Asp-Asp-Asp-Lys-OH; L-Lysine, S-[2,3-bis[(1-oxohexadecyl)oxy]propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-L-phenylalanyl-L-α-aspartyl-L-tyrosyl-L-lysyl-L-α-aspartyl-L-α-aspartyl-L-α-aspartyl-L-α-aspartyl-. Grade: ≥95%. CAS No. 2243206-97-3. Molecular formula: C125H198N24O37S. Mole weight: 2661.15. | |
| FSL-1 TFA salt | FSL-1 is a TLR2/6 peptide agonist (also a putative TLR10 ligand) that activates NF-κB. FSL-1 induces the expression of some pro-inflammatory cytokines such as IL-8, IL-1β, CCL20 and TNF-α in vitro. Synonyms: FSL 1 TFA salt; FSL1 TFA salt; L-Phenylalanine, S-[2,3-bis[(1-oxohexadecyl)oxy]propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-, 2,2,2-trifluoroacetic acid; S-[2,3-Bis[(1-oxohexadecyl)oxy]propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-L-phenylalanine 2,2,2-trifluoroacetic acid; FSL-1 lipoprotein, synthetic TFA salt; Fibroblast-stimulating lipopeptide-1 TFA salt; Pam2-Cys-Gly-Asp-Pro-Lys-His-Pro-Lys-Ser-Phe-OH TFA. Grade: ≥95%. Molecular formula: C86H141F3N14O20S. Mole weight: 1780.18. | |
| FSLLRY-NH2 | FSLLRY-NH2 is a protease-activated receptor 2 (PAR2) inhibitor[1]. Uses: Scientific research. Group: Peptides. CAS No. 245329-02-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P1260. | |
| FSLLRY-NH2 | FSLLRY-NH2 is a selective PAR2 peptide antagonist. It reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice, also suppresses ERK activation and collagen production in isolated cardiac fibroblasts. Synonyms: [Phe1,Ser2,Tyr6]-PAR-1 (1-6) amide (human). CAS No. 245329-02-6. Molecular formula: C39H60N10O8. Mole weight: 796.97. | |
| FSLLRY-NH2 | FSLLRY-NH2. Group: Biochemicals. Grades: Purified. CAS No. 245329-02-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| FSLLRY-NH2 TFA | FSLLRY-NH2 TFA is a selective PAR2 peptide antagonist. It reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice, and also suppresses ERK activation and collagen production in isolated cardiac fibroblasts. Synonyms: H-Phe-Ser-Leu-Leu-Arg-Tyr-NH2.TFA; L-phenylalanyl-L-seryl-L-leucyl-L-leucyl-L-arginyl-L-tyrosinamide trifluoroacetic acid. Grade: ≥95%. Molecular formula: C41H61F3N10O10. Mole weight: 910.99. | |
| FSLLRY-NH2 trifluoroacetate salt | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| FSL-Tyr1 | ?90% (TLC). Group: Fluorescence/luminescence spectroscopy. | |
| FSP-1 | Anticoagulant: irreversible inhibitor of serine proteinase a-thrombine. Fluorocontaining phosphonate, identifies an inflammatory subpopulation of macrophages in the liver. Grade: 99% (NMR). Molecular formula: C17H24F6NO5PS. Mole weight: 499.40. | |
| FSP-2 | Anticoagulant: irreversible inhibitor of serine proteinase a-thrombine. Fluorocontaining phosphonate, synthetised. Grade: 99% (NMR). Molecular formula: C19H28F6NO5PS. Mole weight: 527.46. | |
| FSP-3 | Anticoagulant: irreversible inhibits serine proteinase a-thrombine. Fluorocontaining phosphonate, synthetised. Grade: 99% (NMR). Molecular formula: C19H28F6NO5PS. Mole weight: 527.46. | |
| Fsp4H I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme about 5% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. GC↑NGC CGN↓CG. Activity: 3000-5000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: An E.coli strain that carries the cloned Fsp4H I gene from Flavobacterium species 4H. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 200ug/ml BSA; 1mM DTT; 50% glycerol. Cat No: ET-1114RE. | |
| FT001 | FT001 is a potent, selective and orally effective BET Bromodomain inhibitor with antitumor activity. FT001 inhibits MYC expression with an IC50 of 0.46 μM. FT001 has an effective anti-proliferation effect on MV-4-11, showing obvious MYC mRNA inhibition both in vitro and in vivo. Synonyms: (S)-1-(4-(cyclopropanecarbonyl)-6-(4-(1,1-dioxidothiomorpholino)phenyl)-2-methyl-3,4-dihydroquinoxalin-1(2H)-yl)ethan-1-one; Ethanone, 1-[(2S)-4-(cyclopropylcarbonyl)-6-[4-(1,1-dioxido-4-thiomorpholinyl)phenyl]-3,4-dihydro-2-methyl-1(2H)-quinoxalinyl]-; FT001; FT-001; 1-[(2S)-4-(Cyclopropylcarbonyl)-6-[4-(1,1-dioxido-4-thiomorpholinyl)phenyl]-3,4-dihydro-2-methyl-1(2H)-quinoxalinyl]ethanone. Grade: ≥95%. CAS No. 1778655-51-8. Molecular formula: C25H29N3O4S. Mole weight: 467.58. | |
| FT011 | FT011 is an anti-fibrotic agent, reduces mRNA expression of collagens I and III and inhibits collagen synthesis[1]. FT011 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Asengeprast. CAS No. 1001288-58-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100495. | |
| FT113 | FT113 is a potent inhibitor of fatty acid synthase (FAS/FASN) with IC50 of 213 nM. Synonyms: FT-113; FT113. CAS No. 1630808-89-7. Molecular formula: C22H20FN3O4. Mole weight: 409.41. | |
| FT113 | FT113 is a potent and orally active fatty acid synthase (FASN) inhibitor, with an IC 50 of 213 nM for full-length recombinant human FASN enzyme. In cell-based assay, FT113 blocks FASN activity in BT474 cells (IC 50 , 90 nM). FT113 shows anti-proliferative activity, and exhibits anti-cancer activity both in vitro and in vivo [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1630808-89-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111551. | |
| FT-1518 | FT-1518 is a new generation selective, potent and oral bioavailable inhibitor of mTORC1 and mTORC2, and it shows antitumor activity. Synonyms: FT1518; NSC-802820. CAS No. 1313026-58-2. Molecular formula: C20H26N8O. Mole weight: 394.48. | |
| FT206 | FT206 is a carboxamide ubiquitin-specific protrase inhibitor. (Extracted from patent WO 2020033707 A1, example 11-1). Synonyms: NSC833745; Thieno[2,3-b]pyridine-2-carboxamide, 3-amino-N-[(2S)-6-(3,8-diazabicyclo[3.2.1]oct-3-yl)-1,2,3,4-tetrahydro-2-naphthalenyl]-6-methyl-; 3-Amino-N-[(2S)-6-(3,8-diazabicyclo[3.2.1]oct-3-yl)-1,2,3,4-tetrahydro-2-naphthalenyl]-6-methylthieno[2,3-b]pyridine-2-carboxamide. Grade: ≥98%. CAS No. 2278274-34-1. Molecular formula: C25H29N5OS. Mole weight: 447.60. | |
| FT3967385 | FT3967385 is an inhibitor of USP30 that recapitulates genetic loss of USP30 and sets the trigger for PINK1-PARKIN amplification of mitochondrial ubiquitylation. Synonyms: FT385; (R)-N-(1-cyanopyrrolidin-3-yl)-3-(2-phenoxyphenyl)-1H-pyrazole-5-carboxamide. Grade: ≥95%. Molecular formula: C21H19N5O2. Mole weight: 373.41. | |
| FT671 | FT671 is a potent and selective USP7 inhibitor with high affinity and specificity in vitro and in cells. FT671 destabilises USP7 substrates including MDM2, elevates p53 and results in transcription of p53 target genes, induction of the tumour suppressor p21, and tumour growth inhibition in mice. Synonyms: FT-671; FT 671; (S)-5-((1-(4,4-difluoro-3-(3-fluoro-1H-pyrazol-1-yl)butanoyl)-4-hydroxypiperidin-4-yl)methyl)-1-(4-fluorophenyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one. Grade: >98%. CAS No. 1959551-26-8. Molecular formula: C24H23F4N7O3. Mole weight: 533.48. | |
| FT709 | FT709 is a potent and selective USP9X inhibitor, an IC50 of 82 nM. USP9X has been linked with centrosome function, chromosome alignment during mitosis, EGF receptor degradation, chemo-sensitization, and circadian rhythms[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2413991-74-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145967. | |
| FT895 | FT895 is a potent and selective HDAC11 inhibitor with an IC50 of 3 nM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2225728-57-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-112285. | |
| FT895 | FT895 is a potent and selective inhibitor of HDAC11 with an IC50 of 3 nM. Synonyms: 1H-Isoindole-4-carboxamide, 2,3-dihydro-N-hydroxy-1,1-dimethyl-2-[5-(trifluoromethyl)-2-pyrazinyl]-; N-Hydroxy-1,1-dimethyl-2-[5-(trifluoromethyl)-2-pyrazinyl]-4-isoindolinecarboxamide; 2,3-Dihydro-N-hydroxy-1,1-dimethyl-2-[5-(trifluoromethyl)-2-pyrazinyl]-1H-isoindole-4-carboxamide; HDTK 070; FT-895; FT 895. Grade: ≥95%. CAS No. 2225728-57-2. Molecular formula: C16H15F3N4O2. Mole weight: 352.31. | |
| FTase Inhibitor I | FTase inhibitor I is a potent and selective farnesyltransferase (FTase) inhibitor with an IC50 of 21 nM, which is 30-fold higher for FTase over geranylgeranyl transferase (GGTase; IC50 = 790 nM). Synonyms: Farnesyltransferase Inhibitor I; B581; N-[(2S)-2-[[(2R)-2-amino-3-mercaptopropyl]amino]-3-methylbutyl]-L-phenylalanyl-L-methionine. Grade: ≥95%. CAS No. 149759-96-6. Molecular formula: C22H38N4O3S2. Mole weight: 470.69. | |
| FTase Inhibitor II | FTase Inhibitor II is a cell-permeable analog of farnesyl pyrophosphate (FPP) that potently inhibits FTase with an IC50 of 50-75 nM, and it does not inhibit geranylgeranyl transferase at similar concentrations (IC50 > 100 μM). FTase Inhibitor II is a possible cancer therapeutic agent. Synonyms: Farnesyltransferase Inhibitor II; FTI-II; N-[4-[[(2R)-2-amino-3-mercapto-1-oxopropyl]amino]benzoyl]-L-methionine. Grade: ≥80%. CAS No. 156707-43-6. Molecular formula: C15H21N3O4S2. Mole weight: 371.47. | |
| Ftaxilide | Ftaxilide is an antituberculosis agent used as antiseptic. Synonyms: 2-[(2,6-dimethylphenyl)carbamoyl]benzoic acidFtaxilide2',6'-Dimethylphthalanilic acidHistanorm19368-18-4Ftaxilide [INN:DCF]Ftaxilidum [INN-Latin]Ftaxilida [INN-Spanish]Phthalic 2,6-dimethylanilideUNII-7Z71845H3FMP-12-PMP 12; NSC 16112; MP12; NSC16112; MP-12; NSC-16112Phthalanil. CAS No. 19368-18-4. Molecular formula: C16H15NO3. Mole weight: 269.295. | |
| FTBMT | FTBMT is a novel and selective GPR52 agonist (EC50 = 75 nM, Emax = 122%). FTBMT displays antipsychotic and procognitive properties without causing catalepsy in rodents. Synonyms: 4-[3-[[3-Fluoro-5-(trifluoromethyl)phenyl]methyl]-5-methyl-1H-1,2,4-triazol-1-yl]-2-methylbenzamide. Grade: ≥98% by HPLC. CAS No. 1358575-02-6. Molecular formula: C19H16F4N4O. Mole weight: 392.35. | |
| FTBMT | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| FTI-2148 | FTI-2148 is a potent farnesyltransferase inhibitor with potential antitumor activity. Synonyms: FTI 2148; FTI2148; (S)-2-(5-((((1H-Imidazol-5-yl)methyl)amino)methyl)-2'-methyl-[1,1'-biphenyl]-2-ylcarboxamido)-4-(methylthio)butanoic acid. Grade: 98%. CAS No. 251577-09-0. Molecular formula: C24H28N4O3S. Mole weight: 452.57. | |
| FTI-2153 | FTI-2153 is a potent farnesyltransferase inhibitor. FTI-2153 inhibits bipolar spindle formation during mitosis independently of transformation and Ras and p53 mutation status. FTI-2153 was reported to block bipolar spindle formation and chromosome alignment and causes prometaphase accumulation during mitosis of human lung cancer cells. Synonyms: FTI 2153; FTI2153; (S)-2-[(5-{[(1H-Imidazol-4-ylmethyl)-amino]-methyl}-2''-methyl-biphenyl-2-carbonyl)-amino]-4-methylsulfanyl-butyric acid methyl ester. CAS No. 344900-92-1. Molecular formula: C25H30N4O3S. Mole weight: 466.6. | |
| FTI-249 | FTI-249 is a Farnesyltransferase inhibitor, which potently inhibited FTase (IC50 = 100-200 nM). Synonyms: FTI 249; FTI249; (S)-2-(4-(((R)-2-amino-3-mercaptopropyl)amino)benzamido)-4-(methylthio)butanoic acid. Grade: 98%. CAS No. 161721-65-9. Molecular formula: C15H23N3O3S2. Mole weight: 357.49. | |
| FTI 276 | FTI 276. Group: Biochemicals. Grades: Purified. CAS No. 1217471-51-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| FTI-276 | FTI-276 is a potent and selective farnesyltransferase inhibitor, which is also a tetrapeptide mimetic of the carboxyl terminus of K-Ras4B. FTI-276 blocked the growth in nude mice of a human lung carcinoma that expresses the two most prevalent genetic alterations in human cancers (K-Ras oncogenic mutation and deletion in the tumor suppressor gene p53). In contrast, FTI-276 did not inhibit tumor growth of a human lung carcinoma that harbors no Ras mutations. Furthermore, FTI-276 inhibited oncogenic signaling and tumor growth of NIH 3T3 cells transformed with the ras but not the raf oncogene. Synonyms: FTI276; FTI 276; (S)-2-(5-(((R)-2-amino-3-mercaptopropyl)amino)-[1,1'-biphenyl]-2-ylcarboxamido)-4-(methylthio)butanoic acid. CAS No. 170006-72-1. Molecular formula: C21H27N3O3S2. Mole weight: 433.59. | |
| FTI 276 trifluoroacetate salt | FTI 276 is a Ras CAAX peptidomimetic, a selective inhibitor of farnesyltransferase (FTase) with > 100-fold selectivity over geranylgeranyltransferase I (GGTase I) (IC50 = 0.5 and 50 nM, respectively). It exhibits an inhibitory effect on growth of human lung carcinoma expressing oncogenic K-Ras in nude mice. Synonyms: FTI 276 trifluoroacetate salt; FTI276 trifluoroacetate salt; FTI-276 trifluoroacetate salt; N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine trifluoroacetate salt. Grade: ≥95% by HPLC. CAS No. 1217471-51-6. Molecular formula: C21H27N3O3S2.C2HF3O2. Mole weight: 547.61. | |
| FTI-276 trifluoroacetate salt | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| FTI 277 | FTI 277. Group: Biochemicals. Grades: Purified. CAS No. 1217447-06-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| FTI-277 | FTI-277, a peptide mimetic of the COOH-terminal Cys-Val-Ile-Met of K-Ras4B that inhibited potently FTase in vitro (IC50 = 500 pM) and was highly selective for FTase over geranylgeranyltransferase I (GGTase I) (IC50 = 50 nM). FTI-277, the methyl ester derivative of FTI-276, was extremely potent (IC50 = 100 nM) at inhibiting H-Ras, but not the geranylgeranylated Rap1A processing in whole cells. Treatment of H-Ras oncogene-transformed NIH 3T3 cells with FTI-277 blocked recruitment to the plasma membrane and subsequent activation of the serine/threonine kinase c-Raf-1 in cells transformed by farnesylated Ras (H-RasF), but not geranylgeranylated, Ras (H-RasGG). FTI-277 induced accumulation of cytoplasmic non-farnesylated H-Ras that was able to bind Raf and form cytoplasmic Ras/Raf complexes in which Raf kinase was not activated. Furthermore, FTI-277 blocked constitutive activation of mitogen-activated protein kinase (MAPK) in H-RasF, but not H-RasGG, or Raf-transformed cells. FTI-277 also inhibited oncogenic K-Ras4B processing and constitutive activation of MAPK, but the concentrations required were 100-fold higher than those needed for H-Ras inhibition. The results demonstrate that FTI-277 blocks Ras oncogenic signaling by accumulating inactive Ras/Raf complexes in the cytoplasm, hence preventing constitutive activation of the MAPK cascade. Uses: Radiation-sensitizing agents. Synonyms: FTI-277; FTI 277; FTI277. CAS No. 170006-73-2. M | |
| FTI 277 HCl | FTI-277 inhibits Ras processing with an IC50 of 100 nM, but not the geranylgeranylated Rap1A processing in whole cells. Synonyms: FTI277 HCl; FTI 277 HCl; FTI-277 HCl. Grade: >98%. CAS No. 180977-34-8. Molecular formula: C22H30ClN3O3S2. Mole weight: 484.07. | |
| FTI-277 hydrochloride | FTI-277 hydrochloride is an inhibitor of farnesyl transferase (FTase); a highly potent Ras CAAX peptidomimetic which antagonizes both H- and K-Ras oncogenic signaling. FTI-277 hydrochloride can inhibit hepatitis delta virus (HDV) infection. Uses: Scientific research. Group: Signaling pathways. CAS No. 180977-34-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15872A. | |
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