A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Favipiravir, also known as T-705 or Avigan, is an experimental antiviral drug being developed by Toyama Chemical of Japan with activity against many RNA viruses. Like some other experimental antiviral drugs (T-1105 and T-1106), it is a pyrazinecarboxamide derivative. Favipiravir is active against influenza viruses, West Nile virus, yellow fever virus, foot-and-mouth disease virus as well as other flaviviruses, arenaviruses, bunyaviruses and alphaviruses. Activity against enteroviruses and Rift Valley fever virus has also been demonstrated. Synonyms: T-705; avigan; 6-Fluoro-3-hydroxypyrazine-2-carboxamide. Grade: ≥97%. CAS No. 259793-96-9. Molecular formula: C5H4FN3O2. Mole weight: 157.10.
Favipiravir
Favipiravir (T-705) is a potent viral RNA polymerase inhibitor, it is phosphoribosylated by cellular enzymes to its active form, Favipiravir-ribofuranosyl-5-triphosphate (RTP). Favipiravir-RTP inhibits the influenza viral RNA-dependent RNA polymerase ( RdRP ) activity with an IC 50 of 341 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: T-705. CAS No. 259793-96-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14768.
Favipiravir Impurity 10
Favipiravir Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6-fluoro-3-hydroxypyrazine-2-carboxylic acid. CAS No. 1079990-21-8. Molecular formula: C5H3FN2O3. Mole weight: 158.09. Catalog: APB1079990218.
Favipiravir Impurity 12
Favipiravir Impurity 12. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3,6-dichloropyrazine-2-carboxamide. CAS No. 1023813-21-9. Molecular formula: C5H3Cl2N3O. Mole weight: 192. Catalog: APB1023813219.
Favipiravir Impurity 17
Favipiravir Impurity 17. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1506611-77-3. Molecular formula: C6H6BrN3O2. Mole weight: 232.04. Catalog: APB1506611773.
Favipiravir Impurity 22
Favipiravir Impurity 22. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1257072-34-6. Molecular formula: C5HBrClN3. Mole weight: 218.44. Catalog: APB1257072346.
Favipiravir Impurity 33
Favipiravir Impurity 33. Uses: For analytical and research use. Group: Impurity standards. CAS No. 13301-04-7. Molecular formula: C6H4Br2N2O2. Mole weight: 295.92. Catalog: APB13301047.
Favipiravir Impurity 4
Favipiravir Impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1137606-74-6. Molecular formula: C17H25FN4O. Mole weight: 320.41. Catalog: APB1137606746.
Favipiravir Impurity 40
Favipiravir Impurity 40. Uses: For analytical and research use. Group: Impurity standards. CAS No. 13238-84-1. Molecular formula: C8H12N2. Mole weight: 136.2. Catalog: APB13238841.
Favolon
Favolon is a triterpene antifungal antibiotic produced by Favolaschia sp. 87129. It has anti-fungal activities such as Ascomycetes, Basidiomycetes, Oomycetes and Combinative Fungi. Molecular formula: C33H50O9. Mole weight: 590.74.
Faxeladol
Faxeladol is an opioid analgesic with a higher rate of sudden seizures than tramadol. Uses: An opioid analgesic. Synonyms: GCR9905; GCR 9905; GCR-9905; EM-906; EM 906; EM906; GRT-TA300; GRTA9906; GRTA-9906; GRTA 9906; GRTA0009906; GRTA-0009906; GRTA 0009906; Faxeladol3-((1R,2R)-2-((dimethylamino)methyl)cyclohexyl)phenol. Grade: ≥95%. CAS No. 433265-65-7. Molecular formula: C15H23NO. Mole weight: 233.36.
FaX-IN-1
FaX-IN-1 (compound 11A) is an intermediate in the preparation of FaX inhibitors and was used to study the inhibitory activity against venous thrombosis in rats [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 503614-91-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-75680.
FAZ-3532
FAZ-3532 is a G3BP inhibitor (Kd = 0.54 ?M) which binds to the NTF2L nsP3 binding pocket in G3BP1. FAZ-3532 disrupts the co-condensation of RNA, G3BP1, and caprin 1. FAZ-3532 inhibits G3BP-driven stress granule formation. FAZ-3532 can be studied as a powerful tool to probe the biology of stress granules and a promising interventions designed to modulate stress granule formation[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3036029-72-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162288.
FAZ-3780
FAZ-3780 (compound G3Ib) is an inhibitor of binding to the NTF2L domain of G3BP1/2 that binds to G3BP1 with a Kd of 0.15 ?M. FAZ-3780 targets the protein-protein interaction domain of G3BP1/2 and specifically inhibits co-condensation of G3BP1, caprin 1, and RNA in vitro[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3036029-78-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-162289.
Fazarabine
Fazarabine, also known as Kymarabine, is an orally-active pyrimidine analogue of an aza-substituted cytidine in which the ribose moiety is replaced by an arabinose sugar. Similar in action to cytarabine, fazarabine is phosphorylated by deoxycytidine kinase to a triphosphate form which competes with thymidine for incorporation into DNA; its incorporation into DNA inhibits DNA synthesis, resulting in tumor cell death and tumor necrosis. The presence of deoxycytidine kinase in a tumor is a determinant of tumor sensitivity to this drug. Synonyms: CCRIS 93; CCRIS-93; CCRIS93; NSC 281272; NSC-281272; NSC281272; Ara-AC; 5-Azacytosine arabinoside; 1-beta-D-Arabinofuranosyl-5-azacytosine. CAS No. 65886-71-7. Molecular formula: C8H12N4O5. Mole weight: 244.20.
Fazpilodemab
Fazpilodemab (BFKB8488A) is a humanized bispecific IgG1 antibody that selectively targets and activates fibroblast growth factor receptor 1c (FGFR1c) and Klotho?. Fazpilodemab can be used for the research of type 2 diabetes mellitus (T2DM) or nonalcoholic fatty liver disease (NAFLD)[1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BFKB8488A; RG-7992; RO-7040551. CAS No. 2517935-02-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99614.
FB23
FB23 is a potent and selective FTO demethylase inhibitor with IC50 of 60 nM. FB23 directly binds to FTO and selectively inhibits FTO's m6A demethylase activity. Synonyms: 2-((2,6-Dichloro-4-(3,5-dimethylisoxazol-4-yl)phenyl)amino)benzoic acid. Grade: 98%. CAS No. 2243736-35-6. Molecular formula: C18H14Cl2N2O3. Mole weight: 377.22.
FB23-2
FB23-2 is a potent and selective demethylase inhibitor with IC50 of 2.6 μM. FB23-2 directly binds to FTO and selectively inhibits FTO's m6A demethylase activity. CAS No. 2243736-45-8. Molecular formula: C18H15Cl2N3O3. Mole weight: 392.24.
FB23-2
FB23-2 is a potent and selective inhibitor of mRNA N6-methyladenosine (m6A) demethylase FTO, with an IC50 of 2.6 ?M. FB23-2 has anti-proliferation activity. FB23-2 can be used for the research of acute myeloid leukemia (AML)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2243736-45-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-127103.
FB23 inhibitor
FB23 is a potent and selective inhibitor of N6-methyladenosine (m6A) demethylase FTO (fat mass and obesity associated protein). It moderately inhibits proliferation of NB4 and MONOMAC6 cells. FB23 demonstrates its potent inhibitory impact in AML models. Uses: Designed for use in research and industrial production. Additional or Alternative Names: FB23 inhibitor; FB-23; FB 23. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2243736-35-6. Molecular formula: C18H14Cl2N2O3. Mole weight: 377.22. Purity: >98%. IUPACName: 2-[[2,6-Dichloro-4-(3,5-dimethyl-4-isoxazolyl)phenyl]amino]benzoic acid. Canonical SMILES: O=C(O)C1=CC=CC=C1NC2=C(Cl)C=C(C3=C(C)ON=C3C)C=C2Cl. Product ID: ACM2243736356. Alfa Chemistry ISO 9001:2015 Certified.
Fbl I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 55°C in a total reaction volume of 50 μl. Applications: After 2-fold overdigestion with enzyme approximately 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 100U; 500U. GT↑MKAC CAKM↓TG. Activity: 1000-2000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: An E.coli strain that carries the cloned Fbl I gene from Flavobacterium balustinum. Pack: 10 mM Tris-HCl (pH 7.5); 200 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA, and 50% glycerol. Cat No: ET-1111RE.
F-box protein FBL5 (227-255)
F-box protein FBL5 (227-255) is a peptide corresponding to residues 227-255 of F-box protein FBL5. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination.
FBPase-IN-1
FBPase-IN-1 is a potent FBPase (Fructose-1,6-bisphosphatase) inhibitor for Type 2 diabetes (T2D) study with an IC 50 of 0.22 μM. FBPase-IN-1 can reduce blood glucose levels and ameliorate glucose tolerance. FBPase-IN-1 modifies the C128 site, regulates the N125-S124-S123 allosteric pathway of FBPase and affects the catalytic activity of FBPase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 20362-54-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146725.
Fbxo3 Inhibitor, BC-1215 (N1,N2-bis(4-(Pyridin-2-yl)benzyl)ethane-1,2-diamine, F Box Only Protein 3 Inhibitor, F Box Protein 3 Inhibitor, BC1215, F Box and Leucine-rich Repeat Protein 2 Activator, Fbxl2 Activator)
A cell-permeable, bis-pyridinyl benzyl ethanamine that disrupts Fbxo3-Fbxl2 interaction and effectively prevents SCF-Fbxo3-catalyzed Fbxl2 ubiquitination, resulting in cellular Fbxl2 upregulation and thereby SCF-Fbxl2-catalyzed TRAFs (TNF Receptor-Associated Factors) ubiquitination. Effectively reduces cellular TRAFs (5 to 127uM) and prevents TRAF-mediated cytokines production from LPS-stimulated human PBMC (25uM). Shown to greatly prevent Cecal Ligation & Puncture-induced plasma cytokine elevation and substantially reduce the severity of lung inflammation post intratracheal P. aeruginosa infection in mice (100ug/mouse; i.p.) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?, Primary Target: Fbox3. US Biological Life Sciences.
Worldwide
FBXO41 protein, partial (284-297)
FBXO41 protein, partial (284-297) is a 14-aa peptide. FBXO41 is a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Synonyms: F-box only protein 41 (284-297).
FC-11 is a Tubulin inhibitor that effectively inhibits tumor growth in mice. FC-11 can also induce endoplasmic reticulum (ER) stress to generate excess reactive oxygen species (ROS), leading to mitochondrial damage, thereby promoting apoptosis in colorectal cancer (CRC) cells by targeting microtubules. FC-11 can be used in cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2417298-29-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-155068.
FC131
FC 131 is a CXCR4 antagonist with anti-HIV activity. Synonyms: FC 131; FC-131; FC131; d-Tyr-Arg-Arg-2-Nal-Gly; Cyclo[2-Nal-Gly-D-Tyr-Arg-Arg]. Grade: ≥95%. CAS No. 606968-52-9. Molecular formula: C36H47N11O6. Mole weight: 729.84.
FC 131
FC 131. Group: Biochemicals. Grades: Purified. CAS No. 606968-52-9. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
FC131 TFA
FC131 TFA is a CXCR4 antagonist, inhibits [ 125 I]-SDF-1 binding to CXCR4, with an IC 50 of 4.5 nM. Anti- HIV activity [1]. Uses: Scientific research. Group: Peptides. CAS No. 842166-42-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1104A.
FC131 TFA
FC131 TFA is a CXCR4 antagonist with anti-HIV activity. Synonyms: FC 131 TFA; FC-131 TFA. Molecular formula: C38H48F3N11O8. Mole weight: 843.85.
Fc1-dUTP
Fc1-dUTP, a ferrocene-labelled analogue, is efficiently incorporated into DNA during synthesis, including incorporation of two successive modified nucleotides. Fc1-dUTP is also a satisfactory substrate for PCR. Synonyms: 5-(3-ferrocenecarboxamidopropenyl-1) 2'-deoxyuridine 5'-triphosphate.
FC 99 hydrochloride
FC 99 hydrochloride is an inhibitor of TLR3 expression and suppresses inflammatory responses induced by a synthetic dsRNA (poly(I:C)) and by exogenous IFN-α via IRF3. It inhibits the phosphorylation levels of ERK, JNK, and p38 in varying degrees without altering the total protein. Synonyms: FC 99 hydrochloride; FC99 hydrochloride; FC-99 hydrochloride. Grade: 98%. CAS No. 2734014-73-2. Molecular formula: C15H18N2O.xHCl. Mole weight: 242.32 (free base).
FCCP
As A very potent uncoupler of oxidative phosphorylation in mitochondria, FCCP transports protons across cell membranes which disrupts ATP synthesis. Uses: A very potent uncoupler of oxidative phosphorylation in mitochondria. Synonyms: 2-[[4-(trifluoromethoxy)phenyl]hydrazinylidene]propanedinitrile. Grade: ≥98%. CAS No. 370-86-5. Molecular formula: C10H5F3N4O. Mole weight: 254.17.
FCCP
FCCP. Group: Biochemicals. Grades: Purified. CAS No. 370-86-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
FCCP
FCCP is an uncoupler of oxidative phosphorylation ( OXPHOS ) in mitochondria. FCCP induces activation of PINK1 leading to Parkin Ser65 phosphorylation [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone. CAS No. 370-86-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100410.
FCE 21424
FCE 21424 is produced by the strain of Streptomyces peucetius. Its IC50 inhibitory effect on HeLa and P388 cells was less than that of dunomycin, and its anti-P388 effect was stronger than that of dunomycin in vivo. Synonyms: 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(2R,4R,5S,6aS,8S,10R,10aS)-8-[[(1R,3S)-3-acetyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1-naphthacenyl]oxy]octahydro-2-[(2S)-2-hydroxypropyl]-4,10-dimethylpyrano[3,4-d]-1,3,6-dioxazocin-5-yl]-. Molecular formula: C38H43N3O15. Mole weight: 781.76.
FCE 24366
FCE 24366 is produced by the strain of Streptomyces peucetius. Its IC50 inhibitory effect on HeLa and P388 cells was less than that of dunomycin, and its anti-P388 effect was stronger than that of dunomycin in vivo. Synonyms: 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-[(2R,4R,5S,6aS,8S,10R,10aS)-8-[[(1R,3S)-3-acetyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1-naphthacenyl]oxy]octahydro-2-[(2S)-2-hydroxypropyl]-4,10-dimethylpyrano[3,4-d]-1,3,6-dioxazocin-5-yl]-1,3-dimethyl-. Molecular formula: C40H47N3O15. Mole weight: 809.81.
FCE 24367
FCE 24367 is produced by the strain of Streptomyces peucetius. Its IC50 inhibitory effect on HeLa and P388 cells was less than that of dunomycin, and its anti-P388 effect was stronger than that of dunomycin in vivo. Synonyms: 4,6(1H,5H)-Pyrimidinedione, 5-[(2R,4R,5R,6aS,8S,10R,10aR)-8-[[(1R,3S)-3-acetyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1-naphthacenyl]oxy]octahydro-2-[(2S)-2-hydroxypropyl]-4,10-dimethylpyrano[3,4-d]-1,3,6-dioxazocin-5-yl]dihydro-2-thioxo-. Molecular formula: C38H43N3O14S. Mole weight: 797.82.
FCE 26644
FCE 26644, also known as PNU-145156E, has been found to be a angiogenesis inhibitor that could have probable effect against solid tumours. It has already been discontined. Synonyms: PNU-145156E; PNU145156E; PNU 145156E; FCE26644; FCE-26644; FCE 26644. 7,7'-(Carbonyl-bis(imino-N-methyl-4,2-pyrrolcarbonylimino(N-methyl-4,2-pyrrol)carbonylimino))-bis(1,3-naphthalenedisulfonic acid); 1,3-Naphthalenedisulfonic acid, 7,7'-(carbonylbis(imino(1-methyl-1H-pyrrole-4,2-diyl)carb. Grade: 98%. CAS No. 154788-16-6. Molecular formula: C45H36N10Na4O17S4. Mole weight: 1209.04.
Fcla[chemiluminescence reagent]. Uses: Designed for use in research and industrial production. Additional or Alternative Names: FCLA [CHEMILUMINESCENCE REAGENT]. Product Category: Heterocyclic Organic Compound. CAS No. 131023-60-4. Molecular formula: C36H27N5O7S.Na. Mole weight: 697.701. Product ID: ACM131023604. Alfa Chemistry ISO 9001:2015 Certified.
FCNIrPic
FCNIrPic. Group: other materials. Alternative Names: (iridiuM(III)bis[5-cyano-4-fluorophenyl)pyridinato-N,C2`]picolinate). CAS No. 665005-28-7. Molecular formula: 744.69. Mole weight: C30H14F4IrN5O2. 95%+.
F (continued)
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FD 12-9
FD 12-9 is a dual inhibitor of P-gp and BCRP, with EC50s of 285 nM and 0.9 nM, respectively. It has anti-glioblastoma activity. Synonyms: Ac12Az9. CAS No. 1451741-22-2. Molecular formula: C51H47N3O11. Mole weight: 877.93.
FD223
FD223 is a potent and selective PI3Kδ inhibitor that displays high potency (IC50 = 1 nM) and good selectivity over other isoforms (IC50s of 51 nM, 29 nM and 37 nM, respectively for α, β and γ). FD223 has potential for the research of leukemia such as AML. Grade: 98%. CAS No. 2050524-24-6. Molecular formula: C17H12ClN5O2S. Mole weight: 385.83.
FD-594
FD-594 is produced by the strain of Streptomyces sp. TA-0256. It showed similar or slightly weaker cytotoxicity to adriamycin against HL-60, P388, L1210, HeLa and A549 cells, and moderate antibacterial activity against Gram-positive bacteria. Molecular formula: C47H56O20. Mole weight: 940.93.
FD-838
FD-838 is produced from the mycelia of the basidiomycete Hericium erinaceum. FD-838 inhibits the growth of two plant fungal pathogens Botrytis cinerea and Glomerella cingulata. It has anti-tumor activity. Synonyms: Azaspirofuran A; Antibiotic FD-838; (5R,8S,9R)-2-(5-Ethyl-2-furyl)-3-methyl-8-benzoyl-8-methoxy-9-hydroxy-1-oxa-7-azaspiro[4.4]nona-2-ene-4,6-dione; 1-Oxa-7-azaspiro[4.4]non-2-ene-4,6-dione, 8-benzoyl-2-(5-ethyl-2-furanyl)-9-hydroxy-8-methoxy-3-methyl-, (5S,8S,9R)-. Grade: ≥98%. CAS No. 110341-78-1. Molecular formula: C22H21NO7. Mole weight: 411.41.
FD-891
FD-891 is originally isolated from Streptomyces graminofaciiens A-8890. Its killing activity against human and mouse leukemia cells was 2 to 7 times stronger than that of Doxorubicin, and it also had the activity against Sake yeast. Synonyms: (4Z,6Z,9S,12Z,14Z,16R,17S,18S)-9-[(5S,6R,7R,8S,9S)-5,7-dihydroxy-9-methoxy-6,8-dimethyldecan-2-yl]-2,17-dihydroxy-12,14,16-trimethyl-10,19-dioxabicyclo[16.1.0]nonadeca-4,6,12,14-tetraen-11-one. CAS No. 142383-53-7. Molecular formula: C33H54O8. Mole weight: 578.77.
FD-892
It is originally isolated from FD-892. FD-892 has anti-tumor and anti-sake yeast activity, but the activity is weak. Synonyms: (3E,5E,7R,8S,9E,13E,15E,18S)-8-Hydroxy-3,5,7-trimethyl-18-[(2S)-5,7,9-trihydroxy-6,8-dimethyl-2-decanyl]oxacyclooctadeca-3,5,9,13,15-pentaen-2-one. CAS No. 145177-62-4. Molecular formula: C32H52O6. Mole weight: 532.75.
FDA
FDA. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Fluorescein diacetate. Product Category: Fluorescein Fluorophores. Appearance: White powder. CAS No. 596-09-8. Molecular formula: C24H16O7. Mole weight: 416.3. Purity: 95%+. IUPACName: (6'-acetyloxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl)acetate. Product ID: ACM596098-1. Alfa Chemistry ISO 9001:2015 Certified.
FDA-Approved Drug Library
A unique collection of 1729 FDA approved drugs for high throughput screening (HTS) and high content screening (HCS); - Bioactivity and safety confirmed by pre-clinical research evidence and clinical trials; - An effective tool for discovering new with old drugs and new drug target identification; - Covers various research areas: oncology, cardiology, anti-inflammatory, immunology, neuropsychiatry, analgesia etc- Structurally diverse, medicinally active, and cell permeable; - Rich documentation with structure, target, IC50 value and biological activity description; - NMR and HPLC/LCMS validated to ensure high purity. Uses: Scientific use. Product Category: L4200. Categories: FDA-Approved Drug Libraries.
FDA-Approved Kinase Inhibitor Library
A unique collection of 280 kinase inhibitors for specific targeting of kinases, ready for high-throughput screening and high-content screening. - All compounds have undergone preclinical studies and clinical trials, approved for marketing by FDA, EMA, PMDA, etc. , with proven biological activity and safety. - Detailed instructions, compound structures, target information, IC50 values, activity descriptions, etc. - NMR, HPLC/LCMS and other assay techniques to ensure the correct structure and high purity of the product and reduce false positives. Uses: Scientific use. Product Category: L1610. Categories: FDA-Approved Kinase Inhibitor Libraries.
FDA-Approved & Pharmacopeia Drug Library
3158 compounds from marketed drugs for high throughput screening (HTS) and high content screening (HCS); - All compounds collected in this library are drugs approved by FDA, EMA, PMDA, NMPA, etc. or included in pharmacopoeia such as USP, BP, JP, etc. ; - An effective tool for discovering new with old drugs and new drug target identification; - Covers various research areas, such as Cancer, Cardiovascular disease, Neuroscience, Immunology/Inflammation, respiratory system disease, etc. - More detailed compound information with structure, target, activity, IC50 value, and brief introduction; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1010. Categories: FDA-Approved & Pharmacopeia Drug Libraries.
FD&C Blue #1
FD&C Blue #1. Synonyms: Brilliant Blue FCF. CAS: 3844-45-9. Packing: Box.
New Jersey NJ
FDG
FDG. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Fluoresceindi-β-D-galactopyranoside. Product Category: Fluorescein Fluorophores. CAS No. 17817-20-8. Molecular formula: C32H32O15. Mole weight: 656.58. Purity: 95%+. IUPACName: 3',6'-bis[[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy]spiro[2-benzofuran-3,9'-xanthene]-1-one. Product ID: ACM17817208-1. Alfa Chemistry ISO 9001:2015 Certified.
FDGlcU
FDGlcU. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Fluoresceindi-β-D-glucuronide. Product Category: Fluorescein Fluorophores. Molecular formula: C32H28O17. Mole weight: 684.55. Purity: 95%+. Product ID: ACMA00013915. Alfa Chemistry ISO 9001:2015 Certified. Categories: FDGB Cup.
FDI 6
FDI 6 is an inhibitor of the Forkhead box protein M1 transcription factor (FOXM1) (IC50 value 22.5 μM) that suppresses FOXM1 binding to DNA. FDI6 displaces ?FOXM1 from genomic targets in MCF-7 breast cancer cells, and downregulates concomitant transcription. Synonyms: FDI-6; FDI 6; FDI6; NCGC00099374; NCGC-00099374; NCGC 00099374; 3-amino-6-thiophen-2-yl-4-trifluoromethyl-thieno[2,3-b]pyridine-2-carboxylic acid (4-fluoro-phenyl)-amide; 3-amino-N-(4-fluorophenyl)-6-(2-thienyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide; 3-amino-N-(4-fluorophenyl)-6-(thiophen-2-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide; AC1NPA9B. Grade: 99%. CAS No. 313380-27-7. Molecular formula: C19H11F4N3OS2. Mole weight: 437.43.
FDI-6 is an inhibitor of FOXM1. FDI-6 binds directly to FOXM1 protein, to displace FOXM1 from genomic targets in MCF-7 breast cancer cells, and induce concomitant transcriptional down-regulation. Uses: Scientific research. Group: Signaling pathways. CAS No. 313380-27-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112721.
FD-IN-1
FD-IN-1 is an orally bioavailable and selective inhibitor of factor D (FD) with an IC50 of 12 nM. It also inhibits factor XIa (FXIa) and Tryptase β2 with IC50s of 7.7 and 6.5 μM, respectively. Complement FD is a highly specific S1 serine protease that plays a central role in the alternative complement pathway of the innate immune system. Synonyms: Benzeneacetic acid, 2-[[3'-[(1S)-1-amino-2-hydroxyethyl][1,1'-biphenyl]-3-yl]methoxy]-; (S)-2-(2-((3'-(1-amino-2-hydroxyethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)acetic acid; [2-({3'-[(1S)-1-Amino-2-hydroxyethyl]-3-biphenylyl}methoxy)phenyl]acetic acid. Grade: ≥95%. CAS No. 1646682-14-5. Molecular formula: C23H23NO4. Mole weight: 377.43.