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Faropenem is a penem in the class of beta-lactam antibiotic. Faropenem has a broad-spectrum antibacterial effect against multiple gram-positive and gram-negative microbes. Synonyms: Fropenem; (5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid. Grades: 95%. CAS No. 106560-14-9. Molecular formula: C12H15NO5S. Mole weight: 285.314.
Faropenem daloxate is useful for penem and antibiotics. Faropenem medoxomil has excellent in vitro activity against Streptococcus pneumoniae, Haemophilus influenzae and other key pathogens implicated in acute bacterial rhinosinusitis. Clinical studies have demonstrated that, in the treatment of acute bacterial rhinosinusitis in adults, 7 days of treatment with faropenem medoxomil is as clinically and bacteriologically effective as 10 days of treatment with cefuroxime axetil. One study showed faropenem medoxomil to be superior to cefuroxime axetil. Overall, the safety profile of faropenem medoxomil is similar to that of most comparators. Synonyms: Faropenem medoxil. Grades: >98%. CAS No. 141702-36-5. Molecular formula: C17H19NO8S. Mole weight: 397.4.
Faropenem Impurity 1
An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: sodium 5-(tetrahydrofuran-2-yl)thiazole-4-carboxylate. Grades: > 95%. Molecular formula: C8H8NO3S. Na. Mole weight: 198.22 22.99.
Faropenem Impurity 10
An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: (S,Z)-2-((1S,2R)-1-carboxy-2-hydroxypropyl)-5-(4-hydroxybutylidene)-2,5-dihydrothiazole-4-carboxylic acid. Grades: > 95%. Molecular formula: C12H17NO6S. Mole weight: 303.34.
Faropenem Impurity 11
An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: (R,Z)-2-((1S,2R)-1-carboxy-2-hydroxypropyl)-5-(4-hydroxybutylidene)-2,5-dihydrothiazole-4-carboxylic acid. Grades: > 95%. Molecular formula: C12H17NO6S. Mole weight: 303.34.
Faropenem Impurity 12
Faropenem Impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 153165-72-1. Molecular formula: C5H8O2S. Mole weight: 132.18. Catalog: APB153165721.
Faropenem Impurity 12
An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: (R)-3-((5-((S)-tetrahydrofuran-2-yl)thiazole-4-carbonyl)oxy)butanoic acid. Grades: > 95%. Molecular formula: C12H15NO5S. Mole weight: 285.32.
Faropenem Impurity 13
An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: 5-[(2R)?-tetrahydro-2-furanyl]?- 4-Thiazolecarboxylic acid. Grades: > 95%. CAS No. 613670-77-2. Molecular formula: C8H9NO3S. Mole weight: 199.23.
Faropenem Impurity 14
An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: 4-acetyl-2-(4-hydroxybutylidene)-5-methyl-2,5-dihydrothiophene-3-carboxylic acid. Grades: > 95%. Molecular formula: C11H14O4S. Mole weight: 242.30.
Faropenem Impurity 14
Faropenem Impurity 14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1025974-23-5. Molecular formula: C11H14O4S. Mole weight: 242.29. Catalog: APB1025974235.
Faropenem Impurity 2
An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: sodium 2-((1R,2R)-1-carboxy-2-hydroxypropyl)-5-((S)-tetrahydrofuran-2-yl)-2,3-dihydrothiazole-4-carboxylate. Grades: > 95%. Molecular formula: C12H16NO6S. Na. Mole weight: 302.33 22.99.
Faropenem Impurity 3
An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: sodium 2-((1R,2R)-1-carboxy-2-hydroxypropyl)-5-((S)-tetrahydrofuran-2-yl)-2,3-dihydrothiazole-4-carboxylate. Grades: > 95%. Molecular formula: C12H16NO6S. Na. Mole weight: 302.33 22.99.
Faropenem Impurity 4 Sodium Salt
An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: (5R,?6S)?- 4-Thia-1-azabicyclo[3.2.0]?hept-2-ene-2-carboxylic acid, 6-[(1R)?-1-hydroxyethyl]?-7-oxo-3-[(2R)?-tetrahydro-2-furanyl]?-, Sodium. Grades: > 95%. Molecular formula: C12H14NO6S. Na. Mole weight: 300.31 22.99.
Faropenem Impurity 5
An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: Faropenem dimer impurity. Grades: > 95%. Molecular formula: C24H29N2O11S2. Na. Mole weight: 585.63 22.99.
Faropenem Impurity 55
Faropenem Impurity 55. Uses: For analytical and research use. Group: Impurity standards. CAS No. 104527-11-9. Molecular formula: C13H25NO4Si. Mole weight: 287.43. Catalog: APB104527119.
Faropenem Impurity 6
An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: 4-Thia-1-azabicyclo[3.2.0]?hept-2-ene-2-carboxylic acid, 6-[(1R)?-1-hydroxyethyl]?-7-oxo-3-[(2R)?-tetrahydro-2-furanyl]?-, 2-ethyl ester, (5R,?6S)?-. Grades: > 95%. Molecular formula: C14H19NO5S. Mole weight: 313.38.
Faropenem Impurity 68
Faropenem Impurity 68. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1013911-90-4. Molecular formula: C21H35NO6SSi. Mole weight: 457.66. Catalog: APB1013911904.
Faropenem Impurity 7
An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: 4-Thia-1-azabicyclo[3.2.0]?hept-2-ene-2-carboxylic acid, 6-[1-[[ (1, ?1-dimethylethyl) ?dimethylsilyl]?oxy]?ethyl]?-7-oxo-3- (tetrahydro-2-furanyl) ?-, 2-propenyl ester, [5R-[3(S*)?, ?5α, ?6α(R*)?]?]?- (9CI). Grades: > 95%. CAS No. 120705-68-2. Molecular formula: C21H33NO5SSi. Mole weight: 439.65.
Faropenem Impurity 8
An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: 4-AA Enantiomer. Grades: > 95%. Molecular formula: C13H25NO4Si. Mole weight: 287.43.
Faropenem Impurity 9
An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: sodium (5R,6S)-6-((R)-1-(((R)-3-hydroxybutanoyl)oxy)ethyl)-7-oxo-3-((S)-tetrahydrofuran-2-yl)-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate. Grades: > 95%. Molecular formula: C16H21NO7S. Mole weight: 371.41.
Faropenem Impurity Sodium Salt
An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: (5R,?6S)?- 4-Thia-1-azabicyclo[3.2.0]?hept-2-ene-2-carboxylic acid, 6-[(1R)?-1-hydroxyethyl]?-7-oxo-3-[(2S)?-tetrahydro-2-furanyl]?-, sodium salt (1:1)?. Grades: > 95%. CAS No. 195716-77-9. Molecular formula: C12H14NO5S. Na. Mole weight: 284.31 22.99.
Faropenem intermediate
Faropenem intermediate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Bisphenol F ethoxylate (2 EO/phenol) diacrylate. Product Category: Heterocyclic Organic Compound. CAS No. 120750-67-1. Molecular formula: C18H22O6. Mole weight: 334.364. Purity: 0.96. IUPACName: ethane-1,2-diol,4-[(4-hydroxyphenyl)methyl]phenol,prop-2-enoic acid. Density: 1.15 g/mL at 25ºC(lit.). Product ID: ACM120750671. Alfa Chemistry ISO 9001:2015 Certified.
Faropenem potassium
Faropenem potassium is an orally active beta-lactam antibiotic. It is a prodrug of Faropenem and belongs to the penem group. It is resistant to some forms of extended-spectrum beta-lactamase. Synonyms: 4-Thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-7-oxo-3-(tetrahydro-2-furanyl)-, monopotassium salt, (5R-(3(R*),5-alpha,6-alpha(R*)))-;Potassium (1'R,2''R,5R,6S)-6-(1'-hydroxyethyl)-2-(2''-tetrahydrofuranyl)-penem-3-carboxylate;(5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2S)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate. Grades: >98%. CAS No. 106559-89-1. Molecular formula: C12H14KNO5S. Mole weight: 323.40.
Faropenem Related Compound 1
Faropenem Related Compound 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106560-32-1. Molecular formula: C16H29NO4SSi. Mole weight: 359.56. Catalog: APB106560321.
Faropenem Related Compound 1
An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: (2R)?- 2-Furancarbothioic acid, tetrahydro-, S-[ (2R, ?3S) ?-3-[ (1R) ?-1-[[ (1, ?1-dimethylethyl) ?dimethylsilyl]?oxy]?ethyl]?-4-oxo-2-azetidinyl] ester. Grades: > 95%. CAS No. 106560-32-1. Molecular formula: C16H29NO4SSi. Mole weight: 359.56.
Faropenem Related Compound 2
An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: (3S,?4R)?- 1-Azetidineacetic acid, 3-[ (1R) ?-1-[[ (1, ?1-dimethylethyl) ?dimethylsilyl]?oxy]?ethyl]?-α , ?2-dioxo-4-[[[ (2R) ?-tetrahydro-2-furanyl]?carbonyl]?thio]?-, 2-propen-1-yl ester. Grades: > 95%. CAS No. 429691-43-0. Molecular formula: C21H33NO7SSi. Mole weight: 471.65.
Faropenem Related Compound 3
An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: (5R,?6S)?- 4-Thia-1-azabicyclo[3.2.0]?hept-2-ene-2-carboxylic acid, 6-[ (1R) ?-1-[[ (1, ?1-dimethylethyl) ?dimethylsilyl]?oxy]?ethyl]?-7-oxo-3-[ (2R) ?-tetrahydro-2-furanyl]?-, 2-propen-1-yl ester. Grades: > 95%. CAS No. 120705-67-1. Molecular formula: C21H33NO5SSi. Mole weight: 439.65.
Faropenem Related Compound 4
Faropenem Related Compound 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106559-80-2. Molecular formula: C15H19NO5S. Mole weight: 325.38. Catalog: APB106559802.
Faropenem Related Compound 4
An impurity of Faropenem. Faropenem is an oral penem, closely related to the carbapenem class that is used for the treatment of bacterial infections. Synonyms: (5R,?6S)?- 4-Thia-1-azabicyclo[3.2.0]?hept-2-ene-2-carboxylic acid, 6-[(1R)?-1-hydroxyethyl]?-7-oxo-3-[(2R)?-tetrahydro-2-furanyl]?-, 2-propen-1-yl ester. Grades: > 95%. CAS No. 106559-80-2. Molecular formula: C15H19NO5S. Mole weight: 325.39.
Faropenem sodium
Faropenem sodium is an orally bioavailable penem antibiotic. Faropenem sodium regulates inorganic phosphate transporter Npt1. Faropenem sodium inhibits M. tuberculosis (MIC of 1.3 μg/mL) and B. anthracis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 122547-49-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-76260.
Faropenem sodium
Faropenem is an orally active beta-lactam antibiotic belonging to the penem group. Synonyms: 4-Thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-tetrahydro-2-furanyl]-, sodium salt (1:1), (5R,6S)-; 4-Thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-tetrahydro-2-furanyl]-, monosodium salt, (5R,6S)-; (5R,6S)-6-[(1R)-1-Hydroxyethyl]-7-oxo-3-[(2R)-2-tetrahydrofuryl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid sodium salt; ALP 201; 4-Thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-7-oxo-3-(tetrahydro-2-furanyl)-, monosodium salt, [5R-[3(R*),5α,6α(R*)]]-; Farom; Fropenem; Furopenem; SUN 5555; SY 5555; Wy 49605. Grades: >95%. CAS No. 122547-49-3. Molecular formula: C12H14NO5SNa. Mole weight: 307.30.
Faropenem sodium
Faropenem sodium is the first listed oral penem antibiotic in China. It has a 4-hydrofuran group attached to the 2-position of the parent nucleus of penem. Its chemical structure is relatively stable, and its basic structure is similar to β-lactam antibiotic Chemicalbook, which belongs to the non-typical β-lactam antibiotic. It has good affinity with penicillin and good β-lactamase stability, and is a national class four new drug developed in China. It has broad spectrum antibacterial activity. Synonyms: (+)-(5R, 6S)-6-[(1R)-1-Hydroxyethyl]-7-oxo-3-[(2R)-tetrahydro-2-furyl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylicacid;(5R, 6S, 8R, 2'R)-2-(2'-tetrahydrofuryl)-6-(1-hydroxyethyl)-2-penem-3-carboxylicacid;4-Thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylicacid, 6-(1-hydroxyethyl)-7-oxo-3-(tetrahydro-2-furanyl)-, [5R-[3(R*), 5α, 6Chemicalbookα(R*)]]-;4-Thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylicacid. CAS No. 106560-14-9. Product ID: PAP-0053. Molecular formula: C12H15NO5S. Category: Anti-Infectives. Product Keywords: Antibacterial, Anti-inflammatory and Antiviral Series; Faropenem sodium; PAP-0053; Anti-Infectives; C12H15NO5S; 106560-14-9. Standard: CP. Chemical Name: (5R,6S,8R,2'R)-2-(2'-tetrahydrofuryl)-6-(1-hydroxyethyl)-2-penem-3-carboxylic acid. Grade: Pharmaceutical Grade. Boiling Point: 570.2±50.0 °C(Predicted). Density: 1.56±0.1 g/cm3(Predicted). Product Description: non-typical &b
Faropenem Sodium
Faropenem Sodium. Uses: For analytical and research use. Group: Impurity standards. CAS No. 122547-49-3. Molecular formula: C12H14NNaO5S. Mole weight: 307.3. Catalog: APB122547493.
Faropenem sodium hemipentahydrate
6-[(1R)-1-Hydroxyethyl]-7-oxo-3-[(2R)-tetrahydro-2-furanyl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid monosodium salt hemipentahydrate. inhibits serotonin and noradrenaline reuptake antidepressant antimigraine therapeutic. CAS No. 106560-14-9. Product ID: 8-04330. Molecular formula: 2(C12H14NNaO5S).5(H20). Mole weight: 704.67.
Faropenem Sodium Hemipentahydrate
Useful in organic synthesis. Group: Biochemicals. Grades: Highly Purified. CAS No. 106560-14-9. Pack Sizes: 250mg, 500mg, 1g. Molecular Formula: C??H??NO?SNa 2.5H2O, Molecular Weight: 352.34. US Biological Life Sciences.
10mg Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C12H14NNaO5S. CAS No. 122547-49-3. Prepack ID 89968068-10mg. Molecular Weight 307.3. See USA prepack pricing.
Faropenem sodium Hydrate
Faropenem sodium Hydrate. Group: Biochemicals. Grades: Highly Purified. CAS No. 122547-49-3. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences.
Worldwide
Faropenem Sodium Salt, Hemipentahydrate
Faropenem Sodium Salt, Hemipentahydrate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Farrerol
Botanical Source: The leaves of Rhododendron farrerae and other Rhododendron spp., from Cyrtomium spp., Phormium tenax and Angophora spp. Group: Biochemicals. Alternative Names: CID 442396; (S)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-6,8-dimethyl-4-benzopyrone; (-)-Farrerol. Grades: Highly Purified. CAS No. 24211-30-1. Pack Sizes: 5mg. Molecular Formula: C17H16O5, Molecular Weight: 300.31. US Biological Life Sciences.
Farudodstat is an orally active and potent inhibitor of DHODH (human dihydroorotate dehydrogenase). It inhibits the proliferation of MOLM-14 and KG-1 acute myeloid leukemia (AML) cells (IC50s = 0.582 and 0.382 μM, respectively), as well as induces apoptosis in the same cells when used at concentrations of 0.5 and 1 μM. Synonyms: 2-[(3,5-difluoro-3'-methoxy-[1,1'-biphenyl]-4-yl)amino]pyridine-3-carboxylic acid; ASLAN003; 2-[(3,5-Difluoro-3'-methoxy-4-biphenylyl)amino]nicotinic Acid; 3-Pyridinecarboxylic acid, 2-[(3,5-difluoro-3'-methoxy-[1,1'-biphenyl]-4-yl)amino]-; 2-((3,5-Difluoro-3'-methoxy-[1,1'-biphenyl]-4-yl)amino)nicotinic acid; 2-[(3,5-difluoro-3'-methoxy[1,1'-biphenyl]-4-yl)amino]-3-pyridinecarboxylic acid. Grades: ≥98%. CAS No. 1035688-66-4. Molecular formula: C19H14F2N2O3. Mole weight: 356.32.
Farudodstat
Farudodstat (ASLAN003) is an orally active and potent Dihydroorotate Dehydrogenase (DHODH) inhibitor with an IC50 of 35 nM for human DHODH enzyme. Farudodstat inhibits protein synthesis via activation of AP-1 transcription factors. Farudodstat induces apoptosis and substantially prolongs survival in acute myeloid leukemia (AML) xenograft mice[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ASLAN003. CAS No. 1035688-66-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129239.
Fas-activated serine/threonine kinase
This enzyme is activated during Fas-mediated apoptosis. Following Fas ligation, the enzyme, which is constitutively phosphorylated, is dephosphorylated, and it is the dephosphorylated form that causes phosphorylation of TIA-1, a nuclear RNA-binding protein. Phosphorylation of TIA-1 precedes the onset of DNA fragmentation. Group: Enzymes. Synonyms: FAST; FASTK; STK10. Enzyme Commission Number: EC 2.7.11.8. CAS No. 170347-50-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3159; Fas-activated serine/threonine kinase; EC 2.7.11.8; 170347-50-9; FAST; FASTK; STK10. Cat No: EXWM-3159.
Fascaplysin chloride
Fascaplysin is a cell-permeable red pigment that acts as an inhibitor of cyclin D kinase 4/cyclin D1 (IC50 = 0.35 μM). It is significantly less selective for Cdk6/cyclin D1 (IC50 = 3.4 μM) and does not inhibit other Cdks and tyrosine kinases. Synonyms: NSC 622398. Grades: ≥95%. CAS No. 114719-57-2. Molecular formula: C18H11N2O·Cl. Mole weight: 306.8.
Fascaplysin, Synthetic - CAS 114719-57-2
A cell-permeable red pigment, originally isolated from marine sponge, that acts as a potent, ATP-competitive inhibitor of Cdk4/D1 (IC?? = 0.35 μM). Group: Fluorescence/luminescence spectroscopy.
Fas c-terminal tripeptide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: FAS C-TERMINAL TRIPEPTIDE;AC-SER-LEU-VAL-OH. Product Category: Heterocyclic Organic Compound. CAS No. 189109-90-8. Molecular formula: C16H29N3O6. Mole weight: 359.42. Product ID: ACM189109908. Alfa Chemistry ISO 9001:2015 Certified. Categories: Fas C- Terminal Tripeptide.
Fasedienol
Fasedienol (PH94B) is a neurochemical stimulator of the vomeronasal organ (VON). Fasedienol modulates the olfactory amygdala circuitry of fear and anxiety to alleviate symptoms of PMS and anxiety [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PH94B. CAS No. 23062-06-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145567.
Fasentin is a GLUT1 and GLUT4 inhibitor (IC50 = 68 μM). Fasentin sensitizes Fas receptor in a range of tumor cell lines (IC50 = 20 μM) via regulating the extrinsic apoptotic pathway downstream of TNF receptors but upstream of effector caspases. Synonyms: N-(4-Chloro-3-(trifluoromethyl)phenyl)-3-oxobutanamide. Grades: ≥98% by HPLC. CAS No. 392721-37-8. Molecular formula: C11H9ClF3NO2. Mole weight: 279.64.
Fas/Fc Chimera from mouse
>97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
Fasiglifam
Fasiglifam (TAK-875) is a potent, selective and orally bioavailable GPR40 agonist with EC 50 of 72 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-875. CAS No. 1000413-72-8. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10480.
FAS-IN-1
FAS-IN-1, a diazaspiro derivative, has been found to be a fatty acid synthase inhibitor that probably have potential biological usage in anticancer study. Uses: Fas-in-1 has been found to be a fatty acid synthase inhibitor that probably have potential biological usage in anticancer study. Synonyms: FAS-IN-1; FAS IN 1; CHEMBL2147032; SCHEMBL4541971; OGGOWHOQMIINAZ-UHFFFAOYSA-N; BDBM50391837; BDBM 50391837; BDBM-50391837; CS 3932; CS3932; CS-3932. Grades: 98%. CAS No. 1375105-96-6. Molecular formula: C26H27N3O4S. Mole weight: 477.58.
Inhibitor of fatty acid synthase (FAS) reducing food intake and body weight in mice. Exhibits irreversible slow-binding biphasic inactivation of FAS. Down regulates neuropeptide Y and Agouti-related protein expression. Has been proposed to activiate CPT-1 activity in liver and adipose tissue, leading to increased fatty acid oxidation and energy production. Shows significant in vivo antitumor activity in human breast cancer cells.Suppresses DNA replication and induces apoptosis. FAS inhibition by C75 leads to dramatic accumulation of the CDK inhibitor p27KIP1 from cytosol to cell nuclei. Group: Biochemicals. Alternative Names: [Trans-4-carboxy-5-octyl-3-methylene-butyrolactone]. Grades: Highly Purified. CAS No. 191282-48-1. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Fas Intracellular Domain human
>90% (SDS-PAGE), recombinant, expressed in E. coli (N-terminal histidine tagged), buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy.
Fasinumab
Fasinumab is a human monoclonal antibody to nerve growth factor (NGF). Fasinumab has been undergoing clinical trials for the treatment of osteoarthritis (OA) hip and/or knee pain. Synonyms: REGN475. CAS No. 1190239-42-9.
Fasinumab
Fasinumab (Anti-Human NGF) is a human IgG4 monoclonal antibody to nerve growth factor ( NGF ). Fasinumab can be used in acute sciatica and knee osteoarthritis (OA) studies [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1190239-42-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99195.
Fasitibant chloride hydrochloride
Fasitibant chloride is a selective nonpeptide kinin B2 receptor antagonist. Phase II clinical trials for the treatment of Osteoarthritis were discontinued. Uses: Osteoarthritis. Synonyms: MEN 16132; MEN16132; MEN-16132; (S) -4-amino-5- (4- (4- ( (2, 4-dichloro-3- ( ( (2, 4-dimethylquinolin-8-yl) oxy) methyl) phenyl) sulfonamido) tetrahydro-2H-pyran-4-carbonyl) piperazin-1-yl) -N, N, N-trimethyl-5-oxopentan-1-aminium chloride hydrochloride;1157852-02-2(Fasitibant chloride). Grades: 98%. CAS No. 869880-33-1. Molecular formula: C36H50Cl4N6O6S. Mole weight: 836.71.
Fasnall is a selective fatty acid synthase (FASN) inhibitor with an IC50 of 3.71 ?M. Fasnall induces apoptosis in HER2+ breast cancer cell lines. Fasnall shows potent anti-tumor activities[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 929978-58-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-121250.
Fasnall benzenesulfonate
Fasnall is an inhibitor of fatty acid synthase (FAS) with an IC50 value of 3.71 μM for the human recombinant enzyme. Synonyms: 5,6-Dimethyl-N-[1-(phenylmethyl)-3-pyrrolidinyl]thieno[2,3-d]pyrimidin-4-amine benzenesulfonate; N-(1-Benzylpyrrolidin-3-yl)-5,6-dimethylthieno[2,3-d] pyrimidin-4-amine benzenesulfonate. Grades: ≥98%. CAS No. 2187367-11-7. Molecular formula: C19H22N4S·C6H6O3S. Mole weight: 496.6.
Fasoracetam is a GABA receptor modulator potentially for the treatment of attention deficit hyperactivity disorder. Synonyms: (5R)-5-(piperidine-1-carbonyl)-2-pyrrolidone; (5R)-5-piperidin-1-ylcarbonylpyrrolidin-2-one. CAS No. 110958-19-5. Molecular formula: C10H16N2O2. Mole weight: 196.248.
Fasoracetam
Fasoracetam (NS 105) is the activator of metabotropic glutamate receptor ( mGluR ). Fasoracetam (NS 105) has the potential for the research of attention-deficit hyperactivity disorder (ADHD) and Alzheimer's disease (AD) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NS 105. CAS No. 110958-19-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107481.